association	dataset	threshold value	standardized value
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.921199
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80069
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.84027
REST	ENCODE Transcription Factor Targets	1.0	null
HEC265	CCLE Cell Line Gene CNV Profiles	1.0	2.525
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07318
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835711
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GT-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39148
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041377
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19354
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952508
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0441
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17252
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897081
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.32524
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07507
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.460506
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.784
TCF3	ChEA Transcription Factor Targets	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910902
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27716
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877704
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.87335
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20514
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA polymerase binding	GO Molecular Function Annotations 2025	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.13
CTCF	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43334
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9768
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16346
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
PMC10794847-mmc6.xlsx-PIAS1_KD_up-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91916
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymph_Node-cd141-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.106361
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
CAL78	DepMap CRISPR Gene Dependency	1.0	6.06911
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893384
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860418
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.489151
KP2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.211514
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23865
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00238
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224652
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.45459
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.89835
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT11	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23856
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100102_4_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16928
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14454
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62395
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.524
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902926
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45896
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.43068
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.144
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-1.08562
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Colo-205 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59519
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2853
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218675
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.885
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87769
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22696
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.64537
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15566
MET_knockout_251_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.84131
MELHO	DepMap CRISPR Gene Dependency	1.0	2.58137
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231720,GSE231724_3_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89107
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61938
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16239
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892251
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60705
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.551686
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83956
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46094
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272544
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.48849
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
MET_knockout_247_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.14343
mineral metabolism disease	GWASdb SNP-Disease Associations	1.0	0.430311
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92846
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_immune_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUPT3	CCLE Cell Line Gene Mutation Profiles	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.09
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.42143
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54535
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07039
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64194
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
PMC10087102-LSA-2023-02054_TableS5.xlsx-Sheet_1_-_Supplementary_Table_6-Supplementary_Table_6_PITA_filtered_output_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0664
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HSC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58499
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.462
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982664
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OSBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68622
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.33079
SW-1116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36571
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926531
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.52015
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39571
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.44759
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS934T	CCLE Cell Line Gene Mutation Profiles	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15523
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.836482
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24862
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895846
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917626
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836477
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
OPM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.1993
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93132
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW-48 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18566
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10874
SLR25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8553
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22719
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8488
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1341
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04109
SNU1196	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06512
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247146
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.49094
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
carbohydrate metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45992
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09985
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6331
hsa-miR-3945	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.77431
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55911
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0531
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
hsa-miR-4517	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8556
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
PHYKPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79277
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13306
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.9355
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.393694
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35976
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8938
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.844647
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30068
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848805
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08688
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68953
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40885
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7023
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38975
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879338
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.062987
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11926
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10673
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950096
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03256
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30868
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29802
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63287
PWR-1E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.829654
colonic disease	GWASdb SNP-Disease Associations	1.0	0.953745
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
megacolon	GWASdb SNP-Disease Associations	1.0	0.953745
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU175	CCLE Cell Line Gene Mutation Profiles	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22081
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882817
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.9419
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.11677
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901139
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052165
OCUG1	DepMap CRISPR Gene Dependency	1.0	5.14039
GSE158285_0_v_1_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01391
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.511281
PMC11462941-CAS-115-2947-s001.pdf-136-HES1_HES1	Rummagene Transcription Factor Associations 2026	1.0	null
YKG1	DepMap CRISPR Gene Dependency	1.0	2.42061
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04949
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45923
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0063
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899737
KDM4A	ENCODE Transcription Factor Targets	1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK59	CCLE Cell Line Gene Mutation Profiles	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0029
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9302
PMC7825356-8844261.f3.docx-48-IKZF5_IKZF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31919
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6768
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15098
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.919744
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19336
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
SIN3B	ChEA Transcription Factor Targets	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210625
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64461
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72537
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39392
EN	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	1.0	1.60161
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0033
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47553
short attention span	GWASdb SNP-Phenotype Associations	1.0	0.904931
PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868063
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.3235
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
TC32	DepMap CRISPR Gene Dependency	1.0	7.61387
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.26359
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03493
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2723
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38566
RNA polymerase binding	GO Molecular Function Annotations 2023	1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35206
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55988
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6877
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58317
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41939
BV173	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92112
WM115	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42478
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19687
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17114
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96839
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1009
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
macrophage cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63452
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.645362
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12573
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29676
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20542
mp4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36225
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.663911
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33214
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9383
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41041
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPS510	DepMap CRISPR Gene Dependency	1.0	3.52538
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52203
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230755
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989457
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.601861
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981399
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63848
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19339
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882005
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88724
Pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44188
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487886
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826749
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24934
HEC151	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59384
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066766
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3306
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830788
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16784
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.934599
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37814
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28302
substance dependence	GWASdb SNP-Disease Associations	1.0	0.226391
Perturb_65_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7825
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378931
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23579
hsa-miR-494	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0023
OCILY19	CCLE Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16805
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43223
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220906
S117	DepMap CRISPR Gene Dependency	1.0	3.21528
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840887
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8488
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95822
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02537
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62946
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917626
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870221
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902044
ZR7530	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67613
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59569
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.94884
plasma	GeneRIF Biological Term Annotations	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.484
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53579
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16112
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.20079
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.58149
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53436
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.93209
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45203
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.17985
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02081
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.046422
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07142
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3783
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43763
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898644
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23731
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215132_1_v_3_ptpn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52247
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37728
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32995
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952774
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13041
KALS1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22903
Perturb_16507_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908797
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32056
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
UOK101	CCLE Cell Line Gene CNV Profiles	1.0	1.3377
HEL9217	DepMap CRISPR Gene Dependency	1.0	5.04245
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.542179
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22569
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05873
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.972214
brain disease	GWASdb SNP-Disease Associations	1.0	0.542435
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02633
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07204
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0564
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26926
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03175
CCC5	DepMap CRISPR Gene Dependency	1.0	4.59606
OLIG2	ChEA Transcription Factor Targets	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.81883
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.773
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16465
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.355
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913748
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4197
GSE174383_6_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49173
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.17475
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964222
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMO1	CCLE Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25043
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.934599
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847993
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060796
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3774
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.22991
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860895
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848051
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1724
PSS008	DepMap CRISPR Gene Dependency	1.0	3.2931
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.156893
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16926
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adiponectin	GeneRIF Biological Term Annotations	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
3-methylcrotonyl-CoA carboxylase complex, mitochondrial	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835711
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07344
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36059
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	229.834
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
CTCF-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC2218	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.0293
BL457 (TCERG1)	NURSA Protein Complexes	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4193
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294223
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.62772
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16251
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00468
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
162 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47788
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947834
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073616
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.20153
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066343
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42039
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56799
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.899772
MJ	CCLE Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937115
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.00752
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13041
hsa-miR-299-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16554
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65241
PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6A-targets_down-EWSR1_FLI1-KDM6A_downregulated_targets_upon_KDM6A_knockout_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31583
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day1-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47788
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044519
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887286
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.405582
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09395
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72872
ASPC1	DepMap CRISPR Gene Dependency	1.0	6.11817
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
FMNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33753
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9765
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2533
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.05989
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045949
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.060706
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nanog_KD_GDS1824_134_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
SNU-398	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060569
Bosch-Boonstra-Schaaf optic atrophy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11325
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02338
Testicular leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66875
Perturb_4151_KO_Csmd3_SRP343147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.7788
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988583
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071542
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01892
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03421
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896611
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
SNU398	CCLE Cell Line Gene CNV Profiles	1.0	1.442
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	2.486
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59942
CEBPB	ENCODE Transcription Factor Targets	1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71963
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76485
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKN	DepMap CRISPR Gene Dependency	1.0	3.69685
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03066
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85181
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34401
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39577
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881527
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23146
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
Perturb_15069_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0728
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986523
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059612
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.84289
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869712
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	206.106
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38362
ECGI10	CCLE Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41437
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26138
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.936148
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17671
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58912
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1838	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7315
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06303
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
nucleus	GO Cellular Component Annotations 2023	1.0	null
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20068
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
LC1F	CCLE Cell Line Gene Mutation Profiles	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
icSARS CoV_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00346
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25022
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01378
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45735
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.928855
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26434
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08447
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.8492
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.56838
Subrhabdomeral cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05545
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17303
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.103581
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842853
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83541
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04257
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14996
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01895
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0411
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52975
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.729
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1703
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00462
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82989
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04442
GATA2	ENCODE Transcription Factor Targets	1.0	null
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIHOVCAR3	CCLE Cell Line Gene Mutation Profiles	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882102
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875604
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OACM5-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859839
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.962761
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28413
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82573
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908212
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03709
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07653
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye-corneal epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	8.45572
PMC12081695-41598_2025_1907_MOESM1_ESM.pdf-3-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52392
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216528
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09519
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12739
Attention Deficit Disorder with Hyperactivity	HuGE Navigator Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06496
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41678
FU97	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80826
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SALL4-18804426-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.41677
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4902
RCOR3	ChEA Transcription Factor Targets	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02105
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19494
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07193
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982273
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
SMARCA4	ChEA Transcription Factor Targets	1.0	null
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052044
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933415
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28533
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.835044
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
TP53	ChEA Transcription Factor Targets	1.0	null
MIR34_OE_GDS2755_645_human_HCT116 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
USF2	ENCODE Transcription Factor Targets	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.887753
BL1683 (BUB1)	NURSA Protein Complexes	1.0	null
Otitis Media	HuGE Navigator Gene-Phenotype Associations	1.0	null
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47395
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6123
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.38727
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20466
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77099
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIP5X	DepMap CRISPR Gene Dependency	1.0	5.78776
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.44772
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06908
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8839
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.850477
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
NCIH2227	CCLE Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.554318
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC827	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00124
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841734
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35681
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94713
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
neurod1_17630985_pineal_gland_lof_mouse_gpl1261_gds3000	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.050633
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07653
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32479
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49555
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79568
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-448	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57356
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93882
pd5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54962
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16003
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8536
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5559
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47228
RBBP5	ENCODE Transcription Factor Targets	1.0	null
FMR1_KD_GDS4759_333_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
FD-59-TC81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418055
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42981
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919285
hsa-miR-638	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57327
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6009
RPMI8226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62794
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989919
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.13964
HS936T	DepMap CRISPR Gene Dependency	1.0	2.57644
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RCHACV	CCLE Cell Line Gene Expression Profiles	1.0	1.48352
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
Perturb_16895_KI_Htt_SRP250656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59842
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07961
lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.342739
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31638
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253248
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
Mo-T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909606
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44698
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91039
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883094
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10587
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45434
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08392
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.924
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882021
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82104
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856119
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35815
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74863
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898992
hsa-miR-338-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6258
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
Prostate-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0531806
BT20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4606
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05556
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32883
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.070206
CL34	CCLE Cell Line Gene Mutation Profiles	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831064
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7866-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12027
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08975
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982584
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.831065
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.7196
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	215.321
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970318
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.37
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.8223
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
adhd	GAD Gene-Disease Associations	1.0	null
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0521
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55928
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4572
VMCUB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61775
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06315
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284268
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39535
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.89218
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.752335
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39611
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.268154
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16384
hyperactivity	GWASdb SNP-Phenotype Associations	1.0	0.904931
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3032
SW156	DepMap CRISPR Gene Dependency	1.0	2.83047
GSE246716_0_v_1_trappc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3142
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912864
Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37039
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07405
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257882
RGPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34455
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14235_KO_Tet1_SRP237910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.42762
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66118
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982027
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81423
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47284
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4181_KO_Foxp1_SRP107214	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.07732
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.3571
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93338
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11609
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.083
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19766
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
PMC7940623-41467_2021_21725_MOESM11_ESM.xlsx-Extended_data_table_9_regulons-POU4F1_extended_POU4F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67152
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883835
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10762
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13306
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42178
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856323
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
septopallidal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52118
697	CCLE Cell Line Gene Expression Profiles	1.0	1.6979
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10482
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.083783
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VO-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.888
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20016
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.248948
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235324
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
PLB985	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08971
Tympanic membrane disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24073
RBMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10183
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3629
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894058
Rosacea symptom severity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.61758
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89635
GSE173873_0_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89045
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90057
hsa-miR-512-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.551425
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08699
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01612
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4235
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMRC20	CCLE Cell Line Gene Mutation Profiles	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74975
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01847
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34541
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18725
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880285
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683103
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26656
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.71
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57663
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48976
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65792
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0644
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19764
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042579
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	3.87056
abnormality of ion homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.223565
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03472
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7832
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25033
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.40478
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10357
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847637
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96217
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59371
SARS-CoV MA15_Day1-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.16659
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UMRC7	DepMap CRISPR Gene Dependency	1.0	3.37061
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1355
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54834
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46009
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.16644
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PANC0327	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22993
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834883
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4909
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
hsa-miR-4714-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989267
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.04719
inflammation	GeneRIF Biological Term Annotations	1.0	null
AGS	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10888
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80579
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306691
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7085
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918316
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
AU565	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50391
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6445
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6373
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.04846
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10908
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894615
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186647,GSE217288_2_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiomyopathy, Dilated_Myocardial tissue_GSE3586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31318
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23914
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993095
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360424
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847121
CH157MN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.89807
A673	CCLE Cell Line Gene Expression Profiles	1.0	1.62074
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16707
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
GSE173873_1_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926658
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08304
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71472
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18429
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
detroit551	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.835074
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08639
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4298
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952508
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891295
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26652
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.27
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34842
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25513
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31387
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.907
NCIH660	CCLE Cell Line Gene Expression Profiles	1.0	1.57303
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.6072
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1805
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.295992
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06887
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03948
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12462385-gaaf046_supplementary_data.pdf-3-NEUROD6_NEUROD6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.26992
PMC4791243-oncotarget-06-43452-s006.xlsx-Supplementary_table_S5-Supplementary_table_S5_Differentially_expressed_genes_in_TP53_mutant_versus_TP53_wild_type_cell_lines_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60988
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.76459
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953939
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68558
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942263
kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06079
decreased fasting circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06614
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830298
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54819
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19327
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5172
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842252
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8296
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.5831
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84082
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891699
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899385
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.6047
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06757
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27196
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-430-ZBTB32_ZBTB32	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3797
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03257
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939279
superior frontal gyrus, left, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834432
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
modulator	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872689
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSTB_KO_GSE47516_132_mouse_granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68406
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06607
hsa-miR-510	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
SNU601	DepMap CRISPR Gene Dependency	1.0	2.47933
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.1104
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.4172
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.55146
GSE174383_4_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23245
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061133
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96961
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59201
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2071
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01071
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.54875
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54884
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273071
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4578
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.6053
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.56835
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24398
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92937
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89262
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28605
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03966
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04049
CTCF-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21272
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
NCIH82	CCLE Cell Line Gene Expression Profiles	-1.0	-2.74342
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08836
COGN305	DepMap CRISPR Gene Dependency	1.0	6.86265
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81436
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.59783
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01479
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1701
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58965
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00699
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.8207
OCI-LY-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.0558
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39406
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39664
ZNF471	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49761
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979068
KNS81	DepMap CRISPR Gene Dependency	1.0	4.7517
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04043
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.33079
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84167
hsa-miR-4311	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02458
hsa-miR-216a	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52126
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00141
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39392
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD3-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.322273
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44452
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901223
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03604
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25731
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307879
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04322
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16959
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54301
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.195995
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943302
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08807
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.24831
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982584
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938722
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28962
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21165
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052414
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01584
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0545
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18963
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951742
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3975
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847637
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.10761
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02212
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085396
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34315
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24841
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057791
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LOVO	CCLE Cell Line Gene Mutation Profiles	1.0	null
ESO51	DepMap CRISPR Gene Dependency	1.0	3.64651
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71298
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
attention deficit hyperactivity disorder	GWASdb SNP-Disease Associations	1.0	1.03112
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	219.338
AR	ChEA Transcription Factor Targets	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40997
WASHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38145
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29222
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28639
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	2.08118
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.83383
Perturb_17750_KO_Nurr1/Th1_SRP017560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67903
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12108
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	233.242
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_0_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	dbGAP Gene-Trait Associations	1.0	0.356676
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906497
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22768
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17292
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868045
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04548
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.17137
EGR1	ChEA Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01749
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1651	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72306
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057974
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82512
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15906
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74899
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9475
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042211
hsa-miR-4329	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.544
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
ChIP_CTCF_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE200839,GSE233826_3_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995608
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.752335
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37727
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847637
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955312
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84642
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05962
SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LCAM1	DepMap CRISPR Gene Dependency	1.0	2.37754
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42354
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922176
SMAD3	ChEA Transcription Factor Targets	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.628889
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64179
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4183
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17606
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08461
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05646
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WQ-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.16209
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833784
WM2664	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4737
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46722
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Insulin-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39593
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604904
obesity	GeneRIF Biological Term Annotations	1.0	null
NCIH1963	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840321
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
diabetes	GeneRIF Biological Term Annotations	1.0	null
middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.805213
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35856
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.68957
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
HCT15	CCLE Cell Line Gene Mutation Profiles	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833219
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MERO83	DepMap CRISPR Gene Dependency	1.0	2.33796
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.05032
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65493
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HHV-8_72Hour_18587055_GSE6489	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.1681
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.68241
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19245
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02338
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	2.23661
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0081
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39384
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05197
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986321
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925802
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44362
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.02971
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865399
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0498
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08807
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984576
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08473
WW domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
Response to (pegylated) interferon in HBeAg-negative hepatitis B	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914966
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51212
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11483
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42108
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.396
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24003
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00462
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067985
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59074
SCC-25 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.095512
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09412
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.135957
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08045
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15232
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511005
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	1.65105
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084008
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858426
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TLX1_TLX1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35592
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.20692
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06037
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03704
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer in ever smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84124
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Villous adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.369654
E2F6	ENCODE Transcription Factor Targets	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041286
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66118
BCP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46613
hsa-miR-769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952581
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39622
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
OUMS23	DepMap CRISPR Gene Dependency	1.0	2.32649
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12188
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.998601
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.2586
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96405
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.330164
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.248712
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40828
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65087
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC1005	DepMap CRISPR Gene Dependency	1.0	5.2904
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
HH	CCLE Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8256-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061907
COV644	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01333
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0676
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04427
Diseases in Twins	HuGE Navigator Gene-Phenotype Associations	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intestinal disease	GWASdb SNP-Disease Associations	1.0	0.319682
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981235
TE14	CCLE Cell Line Gene CNV Profiles	1.0	1.67817
UMUC6	DepMap CRISPR Gene Dependency	1.0	3.40351
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.67912
GSE173873_12_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961692
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.8372
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88606
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47721
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8947
GATA3	ENCODE Transcription Factor Targets	1.0	null
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39872
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72376
Periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913079
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56686
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79763
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4974
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25244
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.62077
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899696
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3619
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08822
NALM6	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.148337
MITF	ChEA Transcription Factor Targets	1.0	null
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50679
JUN	ENCODE Transcription Factor Targets	1.0	null
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070687
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80952
PAX3	ChEA Transcription Factor Targets	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933349
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TOV21G	CCLE Cell Line Gene CNV Profiles	1.0	1.45717
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	224.284
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01995
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04955
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.83462
superior frontal gyrus, right, medial bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29064
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.186657
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40561
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05601
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.626
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00429
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74122
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852172
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03426
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19272
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52977
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Carotid intima media thickness x smoking interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.73558
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82357
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45335
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76627
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31833
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24158
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSTB_KO_GDS5091_23_mouse_cerebellar granule	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.71597
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38277
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.986241
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JM1	DepMap CRISPR Gene Dependency	1.0	4.84692
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.60634
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14434
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH838	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.3527
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71953
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918086
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969954
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00462
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08822
Cisplatin-induced hearing loss in childhood cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02056
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09954
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15567
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	2.18417
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23216
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43359
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6638
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00242
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28775
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70566
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.80321
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.911276
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22123
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4475	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TE15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69541
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214202
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22356
SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64841
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.56835
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864649
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09156
PTEN_KD_GDS2958_100_human_HCC827 - NON-SMALL CELL LUNG carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7751
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39046
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3892
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864519
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RAB39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86868
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11578
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48408
type 2 diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52184
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7222
GSE137914_2_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6451
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.131
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.783679
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.82726
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43213
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.18
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880686
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00422
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885659
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53209
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49875
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC15	CCLE Cell Line Gene CNV Profiles	1.0	1.78995
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349771
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42465
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45156
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825905
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	249.155
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051745
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04656
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03298
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06511
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tympanosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Coronary atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02914
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO775	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53766
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9172
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81716
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02914
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53324
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100455
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3826
SUZ12	ENCODE Transcription Factor Targets	1.0	null
adult testis	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17203
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70927
GSE214685_0_v_1_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
iron metabolism disease	GWASdb SNP-Disease Associations	1.0	1.14463
RDES	CCLE Cell Line Gene Expression Profiles	1.0	2.10234
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.46304
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21336
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76761
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2241
attention deficit hyperactivity disorder	GWASdb SNP-Phenotype Associations	1.0	0.904931
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.14097
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37728
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.8768
SNU201	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85493
ESR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65575
GP2D	CCLE Cell Line Gene Mutation Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65493
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colorectal Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24541
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29527
BFTC909	DepMap CRISPR Gene Dependency	1.0	3.71591
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165435
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.55518
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
LbetaT2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5965
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911055
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE148321,GSE169423_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49058
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07612
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0549
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	5.05227
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305322
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	2.20914
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234163
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.5729
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13892
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28359
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08233
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26636
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19663
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68263
MRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68575
MTF2	ChEA Transcription Factor Targets	1.0	null
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34239
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949829
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10058
developmental disorder of mental health	GWASdb SNP-Disease Associations	1.0	0.160005
abnormality of movement	GWASdb SNP-Phenotype Associations	1.0	0.32887
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44502
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34974
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73204
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088515
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81121
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94023
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45092
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.5267
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.453
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68981
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51074
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08444
Perturb_6587_KO_Hira_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966571
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5924
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39393
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93246
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62712
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.066974
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13419
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.038
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3482
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901095
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868891
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35789
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851084
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16901
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.234
Prostate adenocarcinoma_PRAD_TCGA-G9-6494-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18074
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.62349
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Increased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	284.538
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04611
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47104
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	2.09362
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
methylcrotonoyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
diabetes mellitus	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50148
OVK18	CCLE Cell Line Gene CNV Profiles	1.0	1.40457
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
hirschsprung's disease	GWASdb SNP-Disease Associations	1.0	0.953745
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52293
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.0386
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.722
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.39086
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30824
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20091
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.394491
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98149
BACH1	ENCODE Transcription Factor Targets	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_28_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.7592
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976497
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940094
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.858922
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293483
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.69025
hsa-miR-4734	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61243
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65824
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3325
ovary	HPA Tissue Gene Expression Profiles	1.0	1.09832
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064869
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52728
MCAS	CCLE Cell Line Gene CNV Profiles	1.0	1.49295
BD-22-KS33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21588
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	189.932
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66377
VMRCLCD	CCLE Cell Line Gene Mutation Profiles	1.0	null
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45112
TET1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835013
311 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
EHEB	CCLE Cell Line Gene Mutation Profiles	1.0	null
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
Perturb_15786_KO_Tbr1_SRP128068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84654
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01527
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28294
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65057
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04563
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
LU-99A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988428
depression	GWASdb SNP-Phenotype Associations	1.0	0.393867
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
17880687-TableS3	GeneSigDB Published Gene Signatures	1.0	null
OVSAHO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93755
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.23435
abnormality of the cerebral subcortex	GWASdb SNP-Phenotype Associations	1.0	0.354179
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96839
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47325
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82691
JVE015	DepMap CRISPR Gene Dependency	1.0	3.53528
380 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69641
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29658
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93483
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06438
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26524
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04427
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
THNSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0051
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH929	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59224
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835711
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57361
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19375
disease	GWASdb SNP-Disease Associations	1.0	0.052634
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.033357
CTCF	ChEA Transcription Factor Targets	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.773174
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
HS698T	CCLE Cell Line Gene Mutation Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08822
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90186
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04851
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60075
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01721
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49044
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15109
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.31305
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25806
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4309
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6076
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.28088
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20444
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20868
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
KASUMI2	CCLE Cell Line Gene Expression Profiles	1.0	2.02458
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70808
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54823
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.0471
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17671
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08639
ACTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075788
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
chr10_131170138_T_C_b38	GTEx eQTL 2025	1.0	4.88063
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0771
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52187
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843096
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14453
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.985076
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22886
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29927
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09686
GSE231799_2_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9128
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.95174
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39045
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37607
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.69404
FF domain	InterPro Predicted Protein Domain Annotations	1.0	null
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72336
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.8404
mood disorder	GWASdb SNP-Disease Associations	1.0	0.345932
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.049105
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91998
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935046
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.937211
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36059
TOV21G	CCLE Cell Line Gene Mutation Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63402
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32802
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112995,GSE132079_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5843
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08167
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04842
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20313
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32166
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827784
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.049409
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830816
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.105902
colonic mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534647
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.3079
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37888
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
CL11	DepMap CRISPR Gene Dependency	1.0	6.15629
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00327
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-363	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.221321
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH441	Achilles Cell Line Gene Essentiality Profiles	1.0	1.42467
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06064
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.051341
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS675T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72966
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04278
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73669
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09746
Prostate adenocarcinoma_PRAD_TCGA-VP-A87H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2121
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Temperament	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31113
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06908
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84842
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35976
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05604
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08293
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23874
TOV112D	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99348
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47395
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42162
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19073
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16876
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.34916
16391795-Table3	GeneSigDB Published Gene Signatures	1.0	null
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31642
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34074
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31622
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.97182
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IJ-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
RUNX2	ChEA Transcription Factor Targets	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.59466
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.715
SNU1105	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3344
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855448
LNCAPCLONEFGC	CCLE Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Digestive cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.76374
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46874
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37655
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52118
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02537
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	2.39423
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20442
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.66953
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02587
WM1799	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1623	CCLE Cell Line Gene Mutation Profiles	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.054
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.116213
Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.954642
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12586
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32272
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58529
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2904
U343	Achilles Cell Line Gene Essentiality Profiles	1.0	2.6263
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TPBG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59531
ELK1_01_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60927
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45833
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824131
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45678
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860849
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAPAN2	CCLE Cell Line Gene Mutation Profiles	1.0	null
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20934
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40481
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92562_1_v_0_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260017
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17377
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.320318
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32875
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.40978
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2009
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59791
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0634
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.480716
LMSU	CCLE Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lack of perseverance	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35281
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.045
CAPAN-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13455
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949553
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50691
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06142
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04377
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071215
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05928
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
MAFK	ENCODE Transcription Factor Targets	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.079
Learning Disorders	CTD Gene-Disease Associations	1.0	1.30727
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73173
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07059
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0935
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4827
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79085
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25102
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37831
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59519
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13306
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08822
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.48321
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCT116	Achilles Cell Line Gene Essentiality Profiles	1.0	1.6584
abnormality of cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.223565
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41889
specific developmental disorder	GWASdb SNP-Disease Associations	1.0	0.190709
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32663
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847637
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_up-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12343
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12938
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02425
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	390.952
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041045
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043912
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.053
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11609
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05136
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.534439
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053094
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
CHD2	ENCODE Transcription Factor Targets	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45335
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.22488
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948904
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79088
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01703
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91484
COLO-824	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70232
nephroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.383708
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.893034
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754091
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79108
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26243
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91921
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829159
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17292
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18591
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.448064
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051804
MCF7	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	0.951005
TTC642	DepMap CRISPR Gene Dependency	1.0	2.88211
HINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80654
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74188
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30226
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5967
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4167_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the cerebral white matter	GWASdb SNP-Phenotype Associations	1.0	0.462491
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214382,GSE214383_3_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26993
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6789
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31357
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09164
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00242
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235398
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68371
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864976
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03348
abnormality of the large intestine	GWASdb SNP-Phenotype Associations	1.0	0.840142
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19457
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
LC1SQSF	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19901
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16508_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05018
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.872458
Leukemia, Adult T Cell_Blood monocyte_GSE10789	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48749
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL456 (TCERG1)	NURSA Protein Complexes	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.554791
Type II spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7219-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2704
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25022
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15416
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.78707
HCC70	DepMap CRISPR Gene Dependency	1.0	3.23739
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5898
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06607
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-1272	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36642
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.54393
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basolateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28853
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11514
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53425
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31556
COLO320	CCLE Cell Line Gene Mutation Profiles	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34415
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PL4	DepMap CRISPR Gene Dependency	1.0	3.48718
HT55	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	3.27863
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.75944
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.872427
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219826
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of iron homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.00059
abnormality of transition element cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.311139
PMC3921136-CIN-13-2014-021-s001.pdf-199-TBX5_TBX5	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14091
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.01633
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863057
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6131
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04316
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1155
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969126
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04411
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4220_KO_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.12753
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of forebrain morphology	GWASdb SNP-Phenotype Associations	1.0	0.228323
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02931
GSE173873_5_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02382
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041286
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055909
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations	1.0	0.085234
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990425
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10574
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045472
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42029
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041758
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.36926
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
OC316	CCLE Cell Line Gene Mutation Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49735
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31115
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIA1_KO_GSE54418_260_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03604
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	1.37439
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63254
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01995
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14212_KO_Sp8/Sp8_SRP095936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_15983_KO_Larp7_SRP189392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19494
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2687
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20387
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04948
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5071
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
key	GeneRIF Biological Term Annotations	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862757
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200238
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.972241
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08243
IRX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09264
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885861
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44114
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.998119
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hamartoma	DisGeNET Gene-Disease Associations	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.49142
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14976
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52749
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.470375
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2533
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
MFE296	CCLE Cell Line Gene Mutation Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04275
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33945
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8275
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80312
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34737
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77733
MM1S	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.45835
WA-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.06088
Lung adenocarcinoma_LUAD_TCGA-99-8032-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897131
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85605
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1667
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973026
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38221
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.916
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU407	CCLE Cell Line Gene Mutation Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895846
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
YAMATO	DepMap CRISPR Gene Dependency	1.0	5.46747
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13672
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94968
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.144823
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06138
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.101449
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2846
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
HEC59	CCLE Cell Line Gene Mutation Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0509
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835476
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857728
LI7	CCLE Cell Line Gene Mutation Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.983409
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68095
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85349
HT144	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56109
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AKT1_OE_GDS2308_508_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SKMEL3	CCLE Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07505
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93835
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97333
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49237
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.83188
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.97704
CTBP2	ENCODE Transcription Factor Targets	1.0	null
ACSS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2007
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0591
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75458
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08062
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052677
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6077
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1195
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05928
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050445
Perturb_8658_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25274
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12147
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00686
paraseptal subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3892
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874409
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01574
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07681
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	231.037
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33194
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37669
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS18	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09914
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.452962
ZNF143	ENCODE Transcription Factor Targets	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847179
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01995
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30162
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13974
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051142
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.990897
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58548
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416256
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.988393
Colo-320 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.42322
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VI-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12012
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.45807
abnormality of the cerebrum	GWASdb SNP-Phenotype Associations	1.0	0.228323
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07821
Perturb_5022_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGF1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.389
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
EZH2	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31612
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7426
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.46304
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.14607
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92927
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	2.28051
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76279
glucose metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166544
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.123
decreased fasting circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
HRT18	CCLE Cell Line Gene Mutation Profiles	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS746T	CCLE Cell Line Gene CNV Profiles	1.0	2.01046
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38845
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62525
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04468
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288427
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1304
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08821
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14873
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231355
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46868
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941071
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00712
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824078
GSE173873_2_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.77718
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52424
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28358
diabetes mellitus, type 2	GAD Gene-Disease Associations	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38473
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr10_131100412_T_C_b38	GTEx eQTL 2025	1.0	1.0566
KYSE140	CCLE Cell Line Gene Mutation Profiles	1.0	null
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KNS42	CCLE Cell Line Gene Expression Profiles	1.0	1.43086
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4711-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93519
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16442
Obesity	DisGeNET Gene-Disease Associations	1.0	null
ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166544
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25131
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.822979
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7918644-LSA-2020-00974_TableS2.xlsx-1_SABd1_B_D-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54436
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
Internal secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
superior frontal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859552
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964707
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44364
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27433
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70353
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.86223
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07312
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NB1	DepMap CRISPR Gene Dependency	1.0	5.07544
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.527676
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0345
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80248
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1877
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE173873_5_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99143
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16937
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37371
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92609
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69132
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.557
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042242
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	3.40825
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
GSE173873_5_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00942
OCUM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216325
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09825
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
HCT116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40643
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24325
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31444
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12374
CEP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08577
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	7.81582
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830423
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27551
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15666