association	dataset	threshold value	standardized value
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.185675
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81406
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90009
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38179
EGR1	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06913
RUNX2	ChEA Transcription Factor Targets	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.73359
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08584
Spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917935
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
CHL1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45442
ABC1	DepMap CRISPR Gene Dependency	1.0	3.05482
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939022
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.779126
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.20107
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37195
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11726_KO_Ikka_SRP229998	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86325
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31848
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K71493640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46477
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	2.22454
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.62612
JHESOAD1	CCLE Cell Line Gene Expression Profiles	1.0	1.9877
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K59028365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81393
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16976
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61196
Weight Loss	CTD Gene-Disease Associations	1.0	1.31686
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47283018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17641
PCI15A	DepMap CRISPR Gene Dependency	1.0	2.68015
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973748
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.895871
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998037
ABCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39236
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836322
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044412
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4374
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83032
ELK1_01_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61924
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SEPTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9302
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
naftifine-7032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ChEA Transcription Factor Targets	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K36539857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31594
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84169
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06482
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908813
Nemaline myopathy 5A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65323
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12094
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38693
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64425
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03906
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80288
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K14961381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10941
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81399
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
YY1	ChEA Transcription Factor Targets	1.0	null
NFIB	ChEA Transcription Factor Targets	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Perturb_11857_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.41672
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29743
Hypertrophy	CTD Gene-Disease Associations	1.0	1.47634
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.57334
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65855
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K55742134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66614
20208059-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63081
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03084
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.556
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57886
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47859
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.53941
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32412
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9942
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981664
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55985
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00705
ZNF184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21935
OVCAR-8	GDSC Cell Line Gene Expression Profiles	1.0	2.21599
KDM4A	ENCODE Transcription Factor Targets	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88697
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8757
POU5F1	ChEA Transcription Factor Targets	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9415
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20423
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00811
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.34483
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47236
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11101
wortmannin-404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946789
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04061
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.9085
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26919
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.62415
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989672
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986397
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04243
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53176
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40893
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02896
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0653
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A67521865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57403
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90448
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21454
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887157
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K13637593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4412
piP-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8431
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73816
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
CTB-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49906
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08108
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4868
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69777
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3092
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90745
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.647
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6921
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24319929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55887
pyrroline-5-carboxylate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3882
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22164
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60587793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04406
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-A63342325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75816
PPARalpha_OE_GDS2289_244_mouse_Skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70016
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34177
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38136
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.23663
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0079
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901849
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
tocainide-4256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39053
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25745
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.04465
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05915
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2766
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08858
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.79126
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20209
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834131
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K37019305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01685
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40468
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1783
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40146
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2864
BRD-K76544773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75166
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61794
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC10260721-43657_2023_100_MOESM10_ESM.xlsx-MR_for_neuro-traits_FDR_0_05-Gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01943
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915335
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867669
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYCN	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23133
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881954
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Perturb_15835_KO_Per1/Per2_SRP315583	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.95583
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	4.03004
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acrosomal vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
AKAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11739
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66573
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908813
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.924677
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6071
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40808
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1997
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5988
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52091
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867669
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16317
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	1.0	1.71733
Lung adenocarcinoma_LUAD_TCGA-05-4417-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871367
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6482
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13719
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
regulation of sperm capacitation	GO Biological Process Annotations 2023	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861565
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11654
BRD-K84271229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02579
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966491
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
127399	DepMap CRISPR Gene Dependency	1.0	3.07308
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.22101
BRD-K69132276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48472
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366381
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7969
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55973
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38073
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057052
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03701362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08725
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10196
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38226
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.987
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.654584
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0062
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829313
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78
PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20157822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05039
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0654
BRD-K20024676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51856
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.87633
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.9414
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15958
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887783
BRD-A71666580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60424
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60747
cc95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895771
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.050845
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56744
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31747
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08629
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.439
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
GSE109285_5_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32403948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29923
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5882
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50794
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	3.21824
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.03066
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4711
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835287
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6071
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89972
BRD-K03840522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17246
NR0B1	ChEA Transcription Factor Targets	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15385
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18766
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
ESRRB	ChEA Transcription Factor Targets	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15266
BRD-K34343777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25114
raloxifene-5759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85671
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16099
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8556
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.49031
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129189
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OS252	DepMap CRISPR Gene Dependency	1.0	2.36985
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13739
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
act-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.997601
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02037
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.984948
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39318389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08904
CBX8	ENCODE Transcription Factor Targets	1.0	null
BRD-K45699165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06531
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36884445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41523
regulation of cell maturation	GO Biological Process Annotations 2023	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885234
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.52259
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44519
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63911
PECAPJ49	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49871
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.155137
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41988
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5921
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074061
RAD21	ENCODE Transcription Factor Targets	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
Asthma (childhood onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5469
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.565
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.89324
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33102216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00147
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K07383982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75917
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54132
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40311
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954926
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	0.915694
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2226
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A56909893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.303
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.75531
developmental	GAD High Level Gene-Disease Associations	1.0	0.295739
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13242
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201409_1_v_6_coumarin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sperm midpiece	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cefalotin-4482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01943
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38224
20622163-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-A96537953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76564
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7326
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957156
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043952
BRD-K48756106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71923
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.78042
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976697
TUR	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62144
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
E2F1	ChEA Transcription Factor Targets	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896052
BRD-K72386335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45353
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.51214
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.220081
NRL_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41751
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26853
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85202
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93486796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18511
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ovary	HPA Tissue Gene Expression Profiles	1.0	1.14177
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955035
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25602
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67981
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.264
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.629
santonin-4531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7888
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K66675422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62891
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TP-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCI38	DepMap CRISPR Gene Dependency	1.0	2.22136
GI-1	GDSC Cell Line Gene Expression Profiles	1.0	1.58125
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
regulation of sperm capacitation	GO Biological Process Annotations 2025	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28867
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15442833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4506
ESS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52493
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.43092
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8802
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BY-01A-31R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6758
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00448
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949883
BRD-K11880555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43291
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5578
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
acrosomal vesicle	GO Cellular Component Annotations 2025	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6669
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20834
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12171
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70126
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_18608_KO_Bend2_SRP348014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3523
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27685
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36449
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15152
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93967
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83928
BRD-K76755209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9284
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.617
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.55808
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91511
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDIT4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59285
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01397
15(S)-15-methylprostaglandin E2-7489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831315
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11148
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31806
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.30269
9+2 motile cilium	GO Cellular Component Annotations 2023	1.0	null
CRCGN008_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.015
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83503
Recurrent axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10165
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22149
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959996
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41748
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07352
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8629
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
HCFC1	ENCODE Transcription Factor Targets	1.0	null
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
HSD17B4_KO_GDS3468_503_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05302
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61188
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0386
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98208
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06476
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08265
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
thoracic cancer	GWASdb SNP-Disease Associations	1.0	0.424634
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
GPI-PLD_OE_GDS2049_176_human_Hepatoma HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.175
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15503
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.316
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7247
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37881
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ncnc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84322
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67511
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
molsidomine-6325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49076
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13874
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07496
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.25653
MDAMB361	DepMap CRISPR Gene Dependency	1.0	7.19532
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07412
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.46453
RCOR1	ChEA Transcription Factor Targets	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.202142
CTCF_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K12524715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00336
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.045
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.199659
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12349
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857478
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARGC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83415
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31732
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8866
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9587
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07961
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1018
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
pentetrazol-5508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
IPC298	DepMap CRISPR Gene Dependency	1.0	3.96721
tetraethylenepentamine-574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45617
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23372
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26406
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46639
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11188
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527139
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92462
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33952
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68129
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ICC4	DepMap CRISPR Gene Dependency	1.0	6.35755
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11367
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832374
thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520435
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI8402	CCLE Cell Line Gene Expression Profiles	1.0	1.4957
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.001
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48802
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92138
B3GNT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79999
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.996
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.579753
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09493
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77138
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14366
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43262
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.67051
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887783
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8321
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.43074
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92803
SMC3	ENCODE Transcription Factor Targets	1.0	null
RB1_KD_GSE50532_641_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71716
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52503
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15846
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879245
Fanconi anemia complementation group D2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K90408478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91905
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890895
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE108084_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
CHD1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fenofibrate_homo sapiens_gpl4044_gse15494	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32859
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10515
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6339
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.20107
EHEB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SOX9	ChEA Transcription Factor Targets	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7771
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9628
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6663
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0928
GCIY	DepMap CRISPR Gene Dependency	1.0	2.02127
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1132
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3U8-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0743
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95575
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.793
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46594
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27701
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37055068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05684
NCIH2291	CCLE Cell Line Gene Expression Profiles	1.0	1.86877
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.0139
MAPK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61472
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.764927
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48053776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05678
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23905
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14318
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46498
Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49075
Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27964
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825653
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63235
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76502
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08221
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6724
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15161
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A20477000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34274
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834131
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.183
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9431
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827939
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243519
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00502
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08145
BRD-K71755056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47445
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.90285
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.83
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.94325
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19443
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980936
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9405
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828294
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65572
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06985
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68345
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19156
BRD-K14702616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55452
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65927
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50342
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K44483161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03241
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71242
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1243
BRD-K13807637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27794
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	2.19387
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.885862
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6808
Cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K79777851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51844
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91863
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66085
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849051
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
bufexamac-5090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4600_KO_Mettl3_SRP048598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43227
TALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.53403
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30382
BRD-K92632379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0057
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24057
BRD-K31783598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11147
YY1	ENCODE Transcription Factor Targets	1.0	null
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07356
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15071
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.185675
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60221
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02535
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67387
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847208
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93067
RARA_KD_GDS4065_42_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.037928
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44121
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.292
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50950731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72011
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06369
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96646
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56272
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34636
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32645
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99484
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.038637
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.575
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
SCLC21H	CCLE Cell Line Gene CNV Profiles	1.0	1.39909
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.47634
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70426100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86429
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36151
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2024
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970047
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.183
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77338
CRX_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GB2	DepMap CRISPR Gene Dependency	1.0	2.44821
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18518
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84883
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22937
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF641	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8882
Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67303
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61929
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06249
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00193
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1045
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.045287
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.732
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.071
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21723
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00953
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-11A-01R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61071
BRD-K44426506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18214
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
BRD-K62758843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88157
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0102
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98116
GSE211744_2_v_1_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
18691415-Table5e	GeneSigDB Published Gene Signatures	1.0	null
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867659
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.754124
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844965
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0358
Perturb_15773_KO_Nmnat1_SRP324271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.64311
BRD-K30910725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.19458
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3784
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18321
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2228
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86494
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58113
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906774
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49116
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53154
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36185
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09997
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39229
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40561
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47942
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00317
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966052
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3138
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT562	DepMap CRISPR Gene Dependency	1.0	4.45798
BRD-K79982586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80168
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23784
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2353
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03298
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-A18825024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25443
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8071
oxybenzone-5410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9901
HCC202	DepMap CRISPR Gene Dependency	1.0	4.53651
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57956
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6752
BRD-K03957217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.96545
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-6720-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0184
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68183
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.109292
Perturb_5279_OE_Mnx1_ERP140947	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.4199
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2719
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12141
ZFP42	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.41
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.827
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11172604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70825
PRDM14	ChEA Transcription Factor Targets	1.0	null
nalm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
BRD-K14392619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88503
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85779
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2374
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.183
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26304
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11978
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10008
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50036850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.404
BRD-K96624721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66534
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86597
TZM-bl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21505
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04479
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1359	CCLE Cell Line Gene Expression Profiles	1.0	1.60769
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.109318
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08584
CP-320650-01-3822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.098548
CRCGN015_HEPG2_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1817
GTEX-XUZC-1826-SM-4BRVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873968
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.173892
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03035
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.07306
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K63864604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2324
BRD-K54332480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48419
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02724
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ELF1	ENCODE Transcription Factor Targets	1.0	null
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	2.22806
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1507
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11994
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73969
Satellite fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.037
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K20278539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24676
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15769121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76005
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWOO-1526-SM-48TCK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31049
BRD-A65592966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10373
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71111
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.217
Perturb_13273_KO_Spen_SRP198728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.2774
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.84401
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.202142
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9035581-HEP4-6-1157-s002.docx-2-Supplementary_Table_S4_List_of_genes_differentially_expressed_between_FOXS1-positive_and_-negative_HCC_cell_lines_FOXS1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66298
CRCGN017_MCF10A.TP53.M_24H:J02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66135
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45594
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acrosomal vesicle	GO Cellular Component Annotations 2023	1.0	null
COGN305	DepMap CRISPR Gene Dependency	1.0	2.08991
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51914
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054949
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993493
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1316
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.899
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3321
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung squamous cell carcinoma_LUSC_TCGA-22-1017-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03841
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K39046749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96082
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99825
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38936
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
tail	GeneRIF Biological Term Annotations	1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3905
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
SPI1	ENCODE Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6804
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4825
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K64425085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68204
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44389
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12719
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55964
Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41449
cancer	GWASdb SNP-Disease Associations	1.0	0.038663
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75844451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29644
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neoplasm of the breast	GWASdb SNP-Phenotype Associations	1.0	0.517014
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rotenone-5915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.17549
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17835
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5362
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18115
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
salivary gland	HPA Tissue Gene Expression Profiles	1.0	0.845109
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7517
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847835
Down Syndrome_Brain_GSE5390	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72502
PMC3470785-NIHMS377161-supplement-3.pdf-545-PLAGL1_PLAGL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9231
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13433
breast carcinoma	GWASdb SNP-Phenotype Associations	1.0	0.517014
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213112
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41511
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K86774687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24814
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11385
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14318
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64171
GTEX-XGQ4-0626-SM-4AT56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27453
TC-YIK	GDSC Cell Line Gene Expression Profiles	1.0	1.80597
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864311
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98975
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K31884664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31653
BRD-K70315531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2764
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.051
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45102
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2029
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11959
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936129
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00562
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27963
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.529494
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24057
BRD-K51754677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75134
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78949
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01401
NFIB-24661679-LUNG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-3.83999
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.58479
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88094
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19737
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02717
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87234
CRX_NRL_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K83898111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44745
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9433
Lung adenocarcinoma_LUAD_TCGA-73-4668-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5715
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056832
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02184
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24057
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918586
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31344
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72135113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21971
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896655
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.554876
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5815
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988897
MBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
morphology	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26573
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40218
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05273
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12599
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.838826
BRD-K80848948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09628
BRD-A45349889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10181
EBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75615
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55453
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.80288
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.94269
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.7498
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.900321
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K29543978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33961
pi-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
GSE144500_8_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46485
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A74152721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79326
BRD-A45607610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33441
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4208652-phy2-2-e12047.pdf-7-SCMH1_SCMH1	Rummagene Transcription Factor Associations 2026	1.0	null
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	2.03718
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834131
BRD-K93219845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00387
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE214161,GSE214233_0_v_2_zmym2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.870099
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20034
CAPAN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62794
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17562
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72064
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17467
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928781
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-A36171447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16507
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76596
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
CORO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09353
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06923
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.495395
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-nu	GDSC Cell Line Gene Expression Profiles	1.0	1.59842
CRCGN008_HEPG2_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4278
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11216188-peerj-12-17616-s013.pdf-113-HMGA1_HMGA1	Rummagene Transcription Factor Associations 2026	1.0	null
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93735
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0863
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78303
BRD-K72463020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12955
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07893
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.090428
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55032
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K32881384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2051
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.41536
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77848
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.126
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0202
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54544
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68759
Perturb_17493_KO_Gpr115_SRP275685	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.09873
SLR24	DepMap CRISPR Gene Dependency	1.0	2.33023
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.10732
SPI1	ChEA Transcription Factor Targets	1.0	null
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39714
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0613
Perturb_15779_KO_Nrl_SRP009096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828664
hsa-miR-122-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K61034310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45724
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32014
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30207
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60689
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7826
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
VAV2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K34069025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03429
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01943
CRCGN015_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81174
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.14302
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.046695
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5153
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04472
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.61817
BRD-A05823365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92654
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2206
NB6	DepMap CRISPR Gene Dependency	1.0	3.10552
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.247417
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.247417
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23153
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
BRD-K07484899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87919
Perturb_1756_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.52592
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5948
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936129
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69415
BRD-K37515001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0547
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.183
T-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960607
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75469
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23234
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13295
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04194
Reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03246
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
CA46	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84643
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32495
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.019
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72012
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847742
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
BRD-K74107343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94776
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15161
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K91738126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01284
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.149213
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067954
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23894
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT29	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90084
ZNF235	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43123
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.80325
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68655
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K73126584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61257
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
copper sulfate-500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78334
SAP30	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167606
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02377
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.07945
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07413
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4735
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1613
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD3-22036565-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1016
Edema	CTD Gene-Disease Associations	1.0	1.16933
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00224
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68649
42MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97229
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885617
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.3389
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42495
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6182
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32702
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cell maturation	GO Biological Process Annotations 2025	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.616709
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-A67697194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43224
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98974
BRD-K71204648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87988
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K48593237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55714
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61644
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
BRD-A37105798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4684
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367876
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14844
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78886
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
Infertility, Female	CTD Gene-Disease Associations	1.0	1.38584
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160738
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K95007662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26742
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66715
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.303059
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066538
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13881
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
retinal disease	GWASdb SNP-Disease Associations	1.0	0.623422
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39361
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2611
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20788
hsa-miR-4506	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K77041516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07808
BRD-K55220938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33666
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Uterine carcinosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8838
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79115
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.185675
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84311
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06295
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835862
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	GTEx Tissue Gene Expression Profiles	1.0	1.05456
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3001
BRD-K56973599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43754
BRD-K16062794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35211
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K98005735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44676
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55352
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endometrial stromal sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834131
BRD-K26503698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83168
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71207
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26964
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.07057
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946118
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K48406740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55953
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17416171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77961
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74593
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKGT2	DepMap CRISPR Gene Dependency	1.0	4.82885
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8921
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86354
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26514
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01962
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59518944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66637
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27885
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9136
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061784
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39526
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824638
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58164
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24591
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24532125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1761
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
BRD-K70566686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15052
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2441
PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98940411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38848
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	3.37433
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19884
Perturb_7804_KO_Ythdc1_SRP065329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91588
BRD-K04725393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54884
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5721
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45484
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.566
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879979
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
spiramycin-4319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13545
BRD-K77899084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20701
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43014
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972462
iloprost-496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46674
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.866321
16-phenyltetranorprostaglandin E2-7546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33156
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59039
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83823
protein kinase A signaling	GO Biological Process Annotations 2023	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86196
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84473
KG1C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70281
protein kinase A signaling	GO Biological Process Annotations 2025	1.0	null
somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214202
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19078
seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52235
BRD-K28414977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07345
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949664
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12913
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7619
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81962
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28507
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02201
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00714
clorgiline-3219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CL11	DepMap CRISPR Gene Dependency	1.0	3.40733
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.44845
Perturb_16605_KO_Bend2_SRP357909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61916
CAOV4	DepMap CRISPR Gene Dependency	1.0	9.60943
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35782
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1966
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9908
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.38014
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61149
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18611
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.66522
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14038
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6411
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24403
triamterene-7307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866648
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
GSE199541_2_v_5_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7072
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24312
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17793
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0061
MG-63	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10633
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13981
BRD-A68949340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51882
BRD-K36120694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29362
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.040435
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052958
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053215
RPAP3/R2TP/prefoldin-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.862417
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29562
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28162
18398820-table1	GeneSigDB Published Gene Signatures	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57147
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
fulvestrant-7490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11275619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19952
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5555-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNCA_KO_GDS4153_443_mouse_Striatum - 6 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1878
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RBBP5	ENCODE Transcription Factor Targets	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.7283
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30962
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10631
NCIH526	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61901
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51892
CTCF_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23393260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40219
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22155
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10112
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905349
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15161
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58417
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26793
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.50431
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31455
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95115
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.839091
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09065
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02049
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.05085
hsa-miR-4325	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K43000271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78454
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31848
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06825
Cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53889
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60722
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A253	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77062
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18532
COV434	CCLE Cell Line Gene Expression Profiles	1.0	1.62103
RKN	DepMap CRISPR Gene Dependency	1.0	3.52512
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43404
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87272
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82712
COGAR359	DepMap CRISPR Gene Dependency	1.0	5.82543
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055038
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15804_KO_Atf3_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K54751293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57166
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04214
Retrotransposon nucleocapsid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6433
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89481
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Nuclear RNA export factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNA1	MSigDB Cancer Gene Co-expression Modules	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907385
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82795
Uterine corpus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72978
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.889
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07277
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79824
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59048
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65605
BRD-K35380368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60537
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9174
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23157
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46685
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52728
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94079
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847317
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895642
RAD21_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909802
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71745
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22467
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78248
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22889
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044279
Npas4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0126
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
BRD-K61925563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00977
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18743
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15981_KO_Ewsr1_SRP164692	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.54564
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19076
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6721
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29743
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15161
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09267
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167611
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53209
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01397
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8314
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41382866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4608
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3255
BRD-K77743611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21174
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2949-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48613
BRD-A32128687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17539
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
BRD-K11636255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58366
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C8orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77473
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fertility	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91965
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882841
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04775
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27823
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.623422
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43221
Brain Lower Grade Glioma_LGG_TCGA-HT-7604-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S7-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.623422
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7372
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14326
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80859
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01295
KYSE70	DepMap CRISPR Gene Dependency	1.0	2.88489
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	0.529494
WAOSEL	DepMap CRISPR Gene Dependency	1.0	3.0184
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988286
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54937
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NCIH1666	DepMap CRISPR Gene Dependency	1.0	4.64201
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36773
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73039
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81634
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06828
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10637_KO_Sip1_SRP028877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13727
BRD-K18024110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07899
CRCGN008_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.062
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36862
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNCA_KO_GDS4153_527_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81913
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845704
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01743
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.85942
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972154
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A17902629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07618
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92379545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30909
Mitochondrial derivative	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02069
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13519
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1846
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0306
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
HNF4alpha_KO_GDS1916_168_mouse_Embryonic liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97427
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847835
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07905
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954196
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0361
Pleopod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.48665
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6002
KLF4	ChEA Transcription Factor Targets	1.0	null
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90969
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14704
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pentamidine-639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.106
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20887
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957829
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CP-319743-7491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58177
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57005
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03752
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.553627
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905662
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
fulvestrant-367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34081
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38951
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27544
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972154
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
naproxen-7146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2827
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NCIN87	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04792
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80705
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38189
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.862627
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42023
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62717
BRD-K02823077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3131
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.669
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.435
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4685-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06325
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6313
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917473
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04274
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07309
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.50431
GTEX-R55G-2426-SM-2TC5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.034
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.71549
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	108.701
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1179
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.14644
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.765711
OVCAR8	CCLE Cell Line Gene Expression Profiles	1.0	1.89646
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K68495784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00339
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17217
BRD-K45058329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17107
BRD-K76147162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34238
TYKNU	CCLE Cell Line Gene Expression Profiles	1.0	1.77817
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37975
BRD-K76628522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19851
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1406
U-2-OS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A5YI-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00279
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04889
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975241
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.056369
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15266
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.773791
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05445
RBPJ	ChEA Transcription Factor Targets	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58836
CRCGN008_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14615
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.222083
all	GWASdb SNP-Phenotype Associations	1.0	0.038455
LU134A	DepMap CRISPR Gene Dependency	1.0	2.76908
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93322
BRD-K36796440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06613
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0197
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31689
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41748
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01431
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89614
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9726
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43909
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36111748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14199
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09063
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874167
chr6_35160553_G_A_b38	GTEx eQTL 2025	1.0	2.96333
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70206
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
FOXA2	ENCODE Transcription Factor Targets	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37581
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.050267
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26872
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	HPA Tissue Gene Expression Profiles	-1.0	-1.20107
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46339
HCC1143	DepMap CRISPR Gene Dependency	1.0	3.45712
BRD-K53772256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00239
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41528
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899963
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8794
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79973
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.621379
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880782
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384766
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38714
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20274
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49378
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
breast cancer	GWASdb SNP-Disease Associations	1.0	0.608756
GSE162967_5_v_6_fgf21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.4614
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16588281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55725
Testicular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
CRCGN015_MCF10A_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04787
biological_process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K60898929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10987
BRD-K73319967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18675
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68894
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01749
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364139
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3I6-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10944
testis	HPA Tissue Protein Expression Profiles	1.0	1.52259
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
male gamete generation	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07841
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4405
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	1.46177
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55229
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2163
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869682
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SNU46	DepMap CRISPR Gene Dependency	1.0	4.07107
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25701
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84943
rofecoxib-256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.35621
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.68453
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97247086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40416
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
Weight Gain	CTD Gene-Disease Associations	1.0	1.15763
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3746
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69605
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67757
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
COLO205	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3395
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fh8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31636
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22610244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99651
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.266361
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2031
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49554
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43137
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899963
Lung adenocarcinoma_LUAD_TCGA-91-6829-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65142
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K52797126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3266
NANOG-21062744-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41421
Brain Lower Grade Glioma_LGG_TCGA-DU-7011-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99262
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
IKBKG	Hub Proteins Protein-Protein Interactions	1.0	null
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14562
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8639
MYC_Activation - 4 hours_GDS2025_724_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888862
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5412
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45921
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32543
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.03859
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11721
BRD-K53443314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24924
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7162-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.176
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.954132
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
srf_17591768_igmpos_igdpos_b_cells_lof_mouse_gpl339_gds2805	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.813443
CH157MN	DepMap CRISPR Gene Dependency	1.0	3.39448
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A6UC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55216
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K75186244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35405
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36238
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13022
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40683
BRD-K75275329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60796
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
responsible	GeneRIF Biological Term Annotations	1.0	null
gamete generation	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K23241743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47652
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838831
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.922407
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4448
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875145
T-complex 11	InterPro Predicted Protein Domain Annotations	1.0	null
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.8731
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23371
eye disease	GWASdb SNP-Disease Associations	1.0	0.109318
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.704
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315135
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23725
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0065
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74407
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43215
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28494
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36361
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.47506
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06928
octreotide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13142
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1427
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72932
BRD-K35909757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30737
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
E2F6	ENCODE Transcription Factor Targets	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986323
PMC5393594__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81871
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17027
CTCF	ENCODE Transcription Factor Targets	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908813
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35382
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072974
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880391
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1068
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55453
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.59498
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04843
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875105
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.786
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35076
GPR162	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96946
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KY821	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52443
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15537
BRD-K56588599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21554
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35138
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57441129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08808
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57502
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08584
STAT3	ChEA Transcription Factor Targets	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.871657
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K20994897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.002
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.038142
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73123
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19185
GSE210655_3_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.52259
ADNP-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PF-00562151-00-5922	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2347	CCLE Cell Line Gene Expression Profiles	1.0	2.56794
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K66807670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2892
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF507	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59557
SCH	DepMap CRISPR Gene Dependency	1.0	3.31532
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29362
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01627
NCIH446	DepMap CRISPR Gene Dependency	1.0	2.20021
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23703
Liver enzyme levels (alkaline phosphatase)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1301
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03038
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
BRD-K43637338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87312
ethosuximide-7308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12913157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03942
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.589
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76768
Inflammation	CTD Gene-Disease Associations	1.0	1.45009
CRCGN010_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32634
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3948
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_02_26	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61298
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Perturb_10646_KO_Bend2_SRP348014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.23006
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2258
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869302
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98456
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.59025
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4032
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22189453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12917
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.649374
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63055
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.48919
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K65824451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19528
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40658
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26494
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989017
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3117
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.963
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K88625883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73702
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252919
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00868
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21832
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50376
Lung adenocarcinoma_LUAD_TCGA-44-6777-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25082
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33288
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K27236794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34268
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957287
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02761
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869189
levocabastine-7249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27109474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3794
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32053
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56833
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70347
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.58461
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43
Perturb_15872_KO_SMARCA4_SRP293781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.62583
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.29657
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90447
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841839
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36212
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07839
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42828
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64989
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
c8166	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64727
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
DU-4475	GDSC Cell Line Gene Expression Profiles	1.0	1.88767
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
SCC4	DepMap CRISPR Gene Dependency	1.0	3.32824
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PACSIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76371
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45011
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50587
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75397
BRD-K88831197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05072
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25667
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39805
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73241
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890757
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.03793
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62297
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML3-CLOSEST_GENE_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cobalt chloride-454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49219
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0466
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
GSE136311_1_v_0_lyz2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45276
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
hsa-miR-3064-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03367
Perturb_5559_KO_Wdr26_SRP212064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80397
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54064
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921107
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834471
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93891
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.56886
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909685
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.49425
P31-FUJ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51716
BRD-K84246050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15082
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99945
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
LOUNH91	CCLE Cell Line Gene Expression Profiles	1.0	2.45593
Perturb_5056_OE_MERVL_SRP161512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.0709
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82707
BRD-K04108962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96478
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11218
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.735
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10327
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87476
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.623422
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.121858
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95841
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.266361
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.83159
GTEX-Q734-1426-SM-48TZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91575
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08622
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947926
NANOG	ChEA Transcription Factor Targets	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41233
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.13599
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00731
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10879
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67696
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NANOG-21062744-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186397
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06499
reproductive process	GO Biological Process Annotations 2015	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
CL40	CCLE Cell Line Gene Expression Profiles	1.0	3.40787
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
BRD-K88080911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0858
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02769
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89912
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.00545
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40425
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76746
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09378
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16479784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37979
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.46508
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01601
CL11	CCLE Cell Line Gene Expression Profiles	1.0	2.12313
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08584
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.109292
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63395
metformin-3	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17800788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35153
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12171
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64746
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05915
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35661
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77751431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18514
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13268
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00338
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NELFE	ENCODE Transcription Factor Targets	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18246
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03932
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092979
Perturb_666_KD_Ddx5_SRP034716	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.61183
VDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73972
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16369
ferulic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30342
BRD-K50210179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87363
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.569
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49571
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02049
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12955
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
height	GAD Gene-Disease Associations	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863523
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24057
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08977
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF5	ChEA Transcription Factor Targets	1.0	null
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90104
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2214
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24459
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6236
CREM	ChEA Transcription Factor Targets	1.0	null
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46736
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30218
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.411
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11338
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17443
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A08759443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.997
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6524
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfapyridine-6101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898665
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72632
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66919
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.35375
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15161
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49542
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7554-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79515
motility	GeneRIF Biological Term Annotations	1.0	null
cf2th	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.529494
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65142
CRCGN016_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02422
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4576
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40253
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61212
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K81160595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34421
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79295
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.0919
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2151
Prostasome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.89449
sirolimus-402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79833963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33992
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29305
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.47892
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50397
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7438
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K65112040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09997
HLE	CCLE Cell Line Gene Expression Profiles	1.0	1.38605
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLF1	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
CRCGN014_HEPG2_3H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06801
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82695
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19901
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
SU8686	DepMap CRISPR Gene Dependency	1.0	2.82959
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03204
BRD-K71040278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3188
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27213
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01943
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29595
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.965063
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1632
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47213
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976216
thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.640833
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09702
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08584
KP3	DepMap CRISPR Gene Dependency	1.0	2.95161
ATF3	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43119
SIN3A	ENCODE Transcription Factor Targets	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.529494
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919925
MYOG	ENCODE Transcription Factor Targets	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21238
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974548
BRD-K00377328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12346
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4405-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.03084
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39267096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08061
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42605
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06812
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.84142
COLO-824	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43277
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50469
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49771
hsa-miR-892b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82732
BRD-K30963311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58497
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07068
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.55808
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15045
PMC10315050-12920_2023_1588_MOESM2_ESM.pdf-30-ZSCAN23_ZSCAN23	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08605
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08722
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13649
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.98197
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12931
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.529494
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08483
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	2.01691
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7163
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05769
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05669
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95406
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6301
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15456
BRD-U28903152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84173
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74093
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
hybridoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719524
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60313
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69221
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K65626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43121
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.73674
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45657
BRD-A05883068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98928
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28233
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K06846146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36609
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01107
LS-123	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76565
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.047354
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972371
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46159
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901463
BRD-K71808107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12331
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11103
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35537
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15649
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3508
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7315
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73072
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.61883
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5357
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144823
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PCI-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine body mixed cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62042
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15776_OE_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.44233
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25135
Lung adenocarcinoma_LUAD_TCGA-44-8117-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00714
APEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46298
LAMTOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51372
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874585
ZFP42-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26634627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0223
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36764343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22909
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3508
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9001
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28583
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866135
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01873
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6954-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21855
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.33589
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46745
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857631
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K68459574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23265
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86826
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41076
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43694
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
sperm flagellum	GO Cellular Component Annotations 2023	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
ezetimibe_mus musculus_gpl2995_gse39813	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.55353
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.121
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5721
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01425
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38966
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955035
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051371
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2347	GDSC Cell Line Gene Expression Profiles	1.0	2.24585
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905154
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41532
ZNF784	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96256
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72388
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88536
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.18463
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5393594__F4	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18343
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09505
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83689
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51426
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2211
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85741
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81485
Neoplasms	CTD Gene-Disease Associations	1.0	1.02225
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10219
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
C99	DepMap CRISPR Gene Dependency	1.0	2.29354
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51604
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.98
tanespimycin-432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.98499
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14055
BRD-K87722624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06274
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68582
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
BRD-K00793226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13741
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923991
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12931
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.116
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27229
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977656
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.61323
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71965
sperm	GeneRIF Biological Term Annotations	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-AsPC1_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68552
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33956
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826929
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
albendazole-oxide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02313
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS53	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94868
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29097
GTEX-X3Y1-0926-SM-3P5YT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69522
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868807
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1123
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30854
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K86149851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17899
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90924
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
Infertility, Male	CTD Gene-Disease Associations	1.0	1.26359
BRD-K37619154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21166
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967393
BRD-K49467822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06003
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.16035
BRD-K62263376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08768
BRD-A14484404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08816
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23924
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81137
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03761
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.090428
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.080473
PAX5	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18755
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02231
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44984
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899963
496100430_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.10423
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0957
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897651
CCC5	DepMap CRISPR Gene Dependency	1.0	2.0425
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.71615
ZC3H11A_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30173809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50954
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41924
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905066
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.434
PANC1005	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97019
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44005
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.188
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.09751
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6666-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50148
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21936026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09743
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52848
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23934
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY-294002-401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE201882,GSE201883_3_v_4_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6481
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3175
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98521
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04692
SIHA	DepMap CRISPR Gene Dependency	1.0	2.3967
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31848
HS695T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95971
BRD-A55722685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54463
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.077826
BRD-K72255288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22867
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22302
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144500_8_v_11_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5676
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1464
BRD-K27971671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51767
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71699
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.566
BRD-K65564503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8724
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1562
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04846
RCBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49272
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
sulfamethoxypyridazine-2550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HKA1	DepMap CRISPR Gene Dependency	1.0	3.49921
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32434
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71093375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58949
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
PMC11443809-12967_2024_5663_MOESM3_ESM.pdf-82-ZNF174_ZNF174	Rummagene Transcription Factor Associations 2026	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29562
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.61271
JURKAT	CCLE Cell Line Gene Expression Profiles	1.0	1.46923
NFIB-24661679-E16.5 LUNG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69022
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09409
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-2.87118
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872819
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23867157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05813
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.839
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.227397
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7228
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6594
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99101
CRCGN011_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31165
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
Pitcher	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
disease	GWASdb SNP-Disease Associations	1.0	0.036908
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1412
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88348
DLD1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.88021
BRD-K87995704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19891
496100449_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3235
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16046
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98354
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12403
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22194
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
alfuzosin-5605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75678
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03454
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0316
BRD-K35852282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56308
NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27525
Perturb_15741_KO_Nr2e3_SRP086591	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.271
sperm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124952
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8895
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5959
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2023	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Tertiary granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86094
FOXA1	ENCODE Transcription Factor Targets	1.0	null
HCC2157	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
TT2609C02	DepMap CRISPR Gene Dependency	1.0	2.06072
IPC298	CCLE Cell Line Gene Expression Profiles	1.0	1.40974
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36517
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31557
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67865
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the breast	GWASdb SNP-Phenotype Associations	1.0	0.366404
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45646
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69803
alclometasone-6094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19684
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96244
Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1834
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05256
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65513
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039713
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39243
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61065
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05099
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	0.891223
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38828
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1186
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78362
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09645
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07357
BRD-K22608982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12566
Eht	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
Prestwick-920-5056	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48691513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90414
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.979
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TEAD2_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.68584
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963859
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
EVSAT	DepMap CRISPR Gene Dependency	1.0	4.70961