association	dataset	threshold value	standardized value
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5997
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3702
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7164
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.738
Phosphoglycerate kinase 1 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.49574
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3399
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28471
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4334
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastroesophageal reflux disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.01
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myocardial infarction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.534
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4064
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	15.0906
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49676
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreas disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7102
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2644
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.96
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7678
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.94
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.439
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7963
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5393
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
blood	GTEx Tissue Gene Expression Profiles	1.0	0.912911
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3643
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.566
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.1
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2128
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1069
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.567
chr2_21070134_C_T_b38	GTEx eQTL 2025	1.0	1.36747
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
LDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4209
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.413
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25125
SUM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.06607
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5013
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.534
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6154
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68709
Malignant exocrine pancreas neoplasm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Coronary artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.534
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8122
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.883
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1208
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3276
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11292
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3706
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2193
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.485
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07272
Syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
Cornelia de Lange syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Pancreatic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87542
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6958
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4904
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2377
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7893
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0085
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8237
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45392
Endocrine gland cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.734
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1604
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5265
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8812
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2675
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4758
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3998
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.534
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4271
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01794
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7718
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38513
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4859
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_5_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3515
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9019
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.867
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7972
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2148
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.148
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23744
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0242
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
Apolipoprotein B levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10458
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42918
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
GSE111247_0_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4505
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Abdominal obesity-metabolic syndrome 1	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.867
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.71549
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6083
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8547
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6122
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32449
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8006
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5481
HMMR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26678
AKR7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90455
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2401
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5056
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4242
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89838
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.94
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7658
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3349
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0469
colo824	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myocardial infarction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6121
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9787
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8807
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55048
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69841
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8322
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1461
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9197
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2515
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.465
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8948
FAM86B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20864
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1187
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70683
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0983
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38298
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7996
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4724
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5017
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3077
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8674
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7002
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7617
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.94
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3562
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3202
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4375
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10733
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.01
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2119
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8825
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51666
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4681
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11959
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5337
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1314
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6591
PMC8962202-Table2.XLSX-OCI-AML3_30min-Differentially_modulated_proteome_in_OCI-AML3_cells_treated_with_CIGB-300_peptide_during_30_min_respect_to_non-treated_cells_p-value_0_05_and_FC_1_5_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
LDL cholesterol levels in HIV infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12739
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0114
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4666
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6561
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.642
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6618
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.94
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2402
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.765
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0757
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6014
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37727
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0637
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
SW-1116 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
HCC-1954 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0888
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.382
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Activin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Depression in multiple sclerosis (pre-diagnosis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42379
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90663
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2032
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4835
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0088
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1289
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2615
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6849
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.153
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85478
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46486
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62099
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Triglyceride levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25735
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4576
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6986
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0503
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.59
GSE202434,GSE202438_7_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3559
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43112
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6589
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42013
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5685
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1423
HOXD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61483
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3217
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.362
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9112
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48169
Abdominal obesity-metabolic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.897
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
PMC10330983-ab-22-0432-Supplementary-Table-8.pdf-64-TCF12_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8677
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.433
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9012
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0114
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6815
LDL cholesterol levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91076
Rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2433
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4248
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.04
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.325
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1796
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25273
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0433
liver	GTEx Tissue Gene Expression Profiles	1.0	2.18987
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74936