association dataset threshold value standardized value KCTD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70334 Outer ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.053 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.613764 primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28998 APOBEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28111 NCI-H596 COSMIC Cell Line Gene Mutation Profiles 1.0 null visceral mass TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.539 GSE232223_1_v_0_letmd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Tectum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.951 496100612_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63549 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0677 Acoustic neuroma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149124,GSE149128_2_v_1_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 HDGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02554 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.63126 Peripheral vertigo DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.309 KCIMOH1 CCLE Cell Line Gene CNV Profiles 1.0 1.33681 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60349 vestibular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.75024 outer CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48544 GSE217363_4_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null fibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.567585 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09694 SNU478 CCLE Cell Line Gene CNV Profiles 1.0 1.72482 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9971 Sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.338 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4511 hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.653276 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27902 RPS6KA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41856 STARD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59099 Benign recurrent intrahepatic cholestasis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148 Neuron projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.633 Autosomal dominant nonsyndromic deafness 10 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 Septate junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.5855 SETDB1_KO_GSE40296_7_mouse_brain (telencephalon) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Alzheimer Disease HuGE Navigator Gene-Phenotype Associations 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846235 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17911 AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null abnormal nervous system physiology MPO Gene-Phenotype Associations 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21527 Autosomal dominant nonsyndromic deafness 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66865 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2776 SNU1272 CCLE Cell Line Gene CNV Profiles 1.0 1.58377 Alanine aminotransferase levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.0 Utricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.534 Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.722185 NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -1.49116 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31832 MED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08695 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11149 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2061 nervous system phenotype MPO Gene-Phenotype Associations 1.0 null SIRT4_KO_GSE56321_391_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Smooth endoplasmic reticulum cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.74 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6677 CDK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07411 ZNF408 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37063 p2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.589 Autosomal dominant nonsyndromic deafness 17 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.192 MYD88_Deficiency_GDS2650_652_mouse_LUNG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4046 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62022 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17103 Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100512_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63007 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2164 GSE180200,GSE180201_15_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null ANKRD13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33042 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.79556 ZNF133 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47282 HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.791669 LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6635 Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PDCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82919 dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00004 NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5329 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BMPR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71505 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.92007 HDL cholesterol levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.7 Syndactyly type 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72327 alphatectorin GeneRIF Biological Term Annotations 1.0 null P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 2.0509 GSE129370_0_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75662 RERFGC1B DepMap CRISPR Gene Dependency 1.0 27.5582 REC1 CCLE Cell Line Gene CNV Profiles 1.0 2.60167 mediodorsal nucleus of thalamus_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5679 496100330_PCx_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04127 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.858579 NUDHL1 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 GSE135400_1_v_0_kdm1b_human RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 22 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.46 abnormal hearing electrophysiology MPO Gene-Phenotype Associations 1.0 null ZNF248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61044 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1434 PMC4172779-13048_2014_87_MOESM1_ESM.pdf-42-HNF1B_HNF1B Rummagene Transcription Factor Associations 2026 1.0 null FEM1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21144 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9813 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3344 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.556 Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.10458 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6324 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null Autosomal recessive nonsyndromic deafness 18B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.457 CHD2 ENCODE Transcription Factor Targets 1.0 null HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -2.35526 flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243918 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.401007 TLK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54787 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83335 TUBB4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69499 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.753829 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71816 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2639 tectorial GeneRIF Biological Term Annotations 1.0 null Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.774 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.492963 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040469 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Upper tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.215 Myosin IX complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.252 Cochlear hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.049 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4843 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09694 NYNRIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44061 IWS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87039 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.19125 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.97999 apical part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.613318 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4543 RIOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49196 inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.240216 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846235 GSE150134_1_v_0_scn5a_human RummaGEO Gene Perturbation Signatures -1.0 null Usher syndrome type 1F DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 SIRT4_KO_GDS4823_505_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RPS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41909 GSE129725_4_v_0_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neuroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.234 JVM3 CCLE Cell Line Gene CNV Profiles 1.0 2.36393 Otitis interna DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14138 GSE171311_0_v_1_ellagic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.021 DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF100 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91008 BEN COSMIC Cell Line Gene Mutation Profiles 1.0 null Endolymphatic hydrops DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.098 ARID1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92579 EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4385 synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.278877 Autosomal recessive nonsyndromic deafness 86 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.349 496100349_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20425 SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.70851 decreased cochlear nerve compound action potential MPO Gene-Phenotype Associations 1.0 null LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null KIAA2026 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89814 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5901 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.93827 such GeneRIF Biological Term Annotations 1.0 null dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.84086 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.697792 SNU668 CCLE Cell Line Gene CNV Profiles 1.0 1.75551 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09694 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904761 OLIG2 ChEA Transcription Factor Targets 1.0 null Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 PMC3921136-CIN-13-2014-021-s001.pdf-199-TBX5_TBX5 Rummagene Transcription Factor Associations 2026 1.0 null CPEB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32933 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44811 SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4151 GSE92364_1_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null Autosomal recessive nonsyndromic deafness 67 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.678 Apical complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.039 CENPW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82464 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.48764 Cuticular plate COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.94 NCIH1792 CCLE Cell Line Gene Expression Profiles 1.0 1.40223 extracellular matrix COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222224 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.677 brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.251934 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1667 NCIH510 CCLE Cell Line Gene CNV Profiles 1.0 1.34444 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049937 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4607 Midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.885 Apical part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.031 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6434 HCC1897 CCLE Cell Line Gene CNV Profiles 1.0 1.55517 Genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 GSE205332_2_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.14462 GSE163809_1_v_2_sdhaf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8733 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907515 SAS COSMIC Cell Line Gene Mutation Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1633 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.7228 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.302118 STX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38742 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null IPC298 CCLE Cell Line Gene CNV Profiles 1.0 2.0588 decreased cochlear nerve compound action potential MGI Mouse Phenotype Associations 2023 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01316 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36615 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10807 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15558 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05179 Vitelline envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.532 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973271 Lipid storage disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 Synaptic ribbon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.816 termporal pattern GWASdb SNP-Phenotype Associations 1.0 0.481126 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18456 OSBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68622 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 79.1951 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36615 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.899267 SARS-CoV MA15_Day7-C57BL6_None_GSE50878 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.57027 A3KAW CCLE Cell Line Gene Expression Profiles 1.0 1.45768 properties GeneRIF Biological Term Annotations 1.0 null HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.4699 LXR-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1376 GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null RTCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04474 utricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.61111 496100374_HIP_possible Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.51819 NISCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53228 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Space motion sickness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 impaired hearing MPO Gene-Phenotype Associations 1.0 null CRTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19383 NOL4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6795 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null Sexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.761 Autosomal recessive nonsyndromic deafness 24 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214 thyroid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.661929 cochlea TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.7965 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 Inner hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.376 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_2_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null TCP10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26109 ZC3H3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31037 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31705 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.327 Stereocilia tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.381 GSE188870,GSE188871_4_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152699,GSE152723_3_v_1_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null A704 CCLE Cell Line Gene Expression Profiles 1.0 1.8954 Zona pellucida domain InterPro Predicted Protein Domain Annotations 1.0 null A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.76411 chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 4.07889 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55774 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null LDL cholesterol levels in current drinkers GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 High density lipoprotein cholesterol levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.6 NIF3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90755 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08204 GATA4_KO_GDS3486_483_mouse_jejunum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.48584 PARP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58461 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 0.966547 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.922362 GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null CNPPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52577 GSE221327_4_v_2_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null GSE247764_4_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61931 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956513 GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.546 GCT DepMap CRISPR Gene Dependency 1.0 2.16426 Zymogen granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.798 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26154 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846235 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.676172 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3849 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.023 Autosomal dominant auditory neuropathy 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15 GSE132386_2_v_0_ppara_mouse RummaGEO Gene Perturbation Signatures -1.0 null RBM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71002 extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.202684 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.46868 SYNGR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57479 Perturb_8016_KD_MIDN_SRP361845 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.18106 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2143 KARPAS299 CCLE Cell Line Gene CNV Profiles -1.0 -1.374 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.563 ATM_Deficiency_GDS1544_769_mouse_Lymph nodes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null LPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7796 SIRT1_KO_GDS3666_295_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null liver GTEx Tissue Gene Expression Profiles 1.0 1.24419 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62098 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE180200,GSE180201_5_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 NCI-H847 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.2511 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.806 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 DepMap CRISPR Gene Dependency 1.0 4.0321 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08468 GSE158632_2_v_0_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Interstitial keratitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2033 extracellular region part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.91549 SNU-398 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40475 Autosomal recessive nonsyndromic deafness 42 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.512 496100389_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6964 Autosomal recessive nonsyndromic deafness 28 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.566 GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.847 KDM4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37368 ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 91 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.521 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.9097 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840376 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.17274 FOS ENCODE Transcription Factor Targets 1.0 null abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.10345 GSE244072_4_v_6_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6986 PRSS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28828 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18689 anchored component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.46766 GSE226249_0_v_1_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.23099 496100304_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59614 apical complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.620104 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null GSE132386_1_v_0_ppara_mouse RummaGEO Gene Perturbation Signatures -1.0 null MM370 DepMap CRISPR Gene Dependency 1.0 3.11943 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4584 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052618 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96468 ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87216 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.06296 auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.3555 HS746T CCLE Cell Line Gene CNV Profiles 1.0 2.19058 CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null MONOMAC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.54696 TCF7L2-21901280-H4IIE-RAT ChEA Transcription Factor Targets 2022 1.0 null TCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1464 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31781 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7476 Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.593 DOC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81097 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2614 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.853368 GER cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.117 Lateral wall of outer hair cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.008 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.57256 GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDL cholesterol levels in current drinkers GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08468 TCF21 ChEA Transcription Factor Targets 1.0 null HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2004 RH30 CCLE Cell Line Gene CNV Profiles 1.0 1.59332 Exine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.664 Matrilin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.678 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRR35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4966 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840376 Perturb_4134_KO_Trrap_SRP198540 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.89042 ovary GTEx Tissue Gene Expression Profiles -1.0 -1.2409 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Endoplasmic reticulum cisternal network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 Autosomal dominant nonsyndromic deafness 33 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.689 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064223 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00833 FGD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96266 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16124 Supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.078 HMG20A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64166 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1525 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.29393 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.41486 Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09694 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840376 SEC22C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14506 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.26646 TMEM187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8381 X-linked nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115 Stereocilium bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.774 CTTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33109 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4868 Autosomal dominant nonsyndromic deafness 7 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 MIA-PACA-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2903 PAQR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50302 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890142 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50522 enlarged tectorial membrane MGI Mouse Phenotype Associations 2023 1.0 null Amniocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656 PPARG ChEA Transcription Factor Targets 1.0 null extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Serum alkaline phosphatase levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.42218 HAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3218 CAB39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76903 SYP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91323 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.295 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968144 posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52784 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.446 Inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.858 SNU119 CCLE Cell Line Gene CNV Profiles -1.0 -2.20303 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7645-01A-22R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU5 CCLE Cell Line Gene Expression Profiles 1.0 1.99332 U937 CCLE Cell Line Gene Expression Profiles 1.0 1.59083 Usher syndrome type 1J DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.37 probably GeneRIF Biological Term Annotations 1.0 null Autosomal dominant nonsyndromic deafness 41 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22358 MITF ChEA Transcription Factor Targets 1.0 null Enlarged vestibular aqueduct DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.711 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973271 Autosomal dominant nonsyndromic deafness 4B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.773 AARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08429 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Scent gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.735 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043086 stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.376494 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4735 DDIT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85491 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4678 EEF1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2911 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.29633 Cluster of actin-based cell projections COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.394 MCAS CCLE Cell Line Gene CNV Profiles 1.0 1.51693 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.54894 GSE171292_1_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 MISP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79202 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969765 Punctate palmoplantar keratoderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.156 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5743 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0928 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.548914 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.05071 A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.35127 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04033 NR3C1 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH524 CCLE Cell Line Gene CNV Profiles -1.0 -1.72924 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.023883 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845833 PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4444 17660535-TableS4b GeneSigDB Published Gene Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cochlear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04836 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8351 Visceral mass TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.04 VENTX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2314 496100373_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.54677 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1061 Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35514 ETS1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null E2F8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98573 GATA3-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE85565_1_v_0_tcf21_human RummaGEO Gene Perturbation Signatures -1.0 null nucleotide GeneRIF Biological Term Annotations 1.0 null GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cortical actin cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.282 CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927061 Autosomal recessive nonsyndromic deafness 84A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.526 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.338 SNU1272 CCLE Cell Line Gene Expression Profiles -1.0 -1.80272 BHMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9015 HESX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3511 outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06662 METTL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18039 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUBG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64816 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.93911 fetal membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117425 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUSP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41647 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88266 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72087 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4690-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51969 BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4422 Brain - Spinal cord (cervical c-1) GTEx Tissue Gene Expression Profiles 2023 1.0 1.51685 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74509 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.712 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1 Rummagene Transcription Factor Associations 2026 1.0 null NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null PPOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65057 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr10_112239643_G_A_b38 GTEx eQTL 2025 1.0 1.16652 PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.321 Punctate palmoplantar keratoderma type I DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.5 GSE158632_2_v_1_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SL-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917934 Wolfram syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.356 GAPDHS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46245 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904761 Autosomal dominant nonsyndromic deafness 13 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.579 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09361 NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.38126 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0993 LIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8098 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.866536 stria vascularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59124 TOV21G CCLE Cell Line Gene CNV Profiles 1.0 1.44743 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R8-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.77458 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.23661 Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.8508 proteinaceous extracellular matrix GO Cellular Component Annotations 2015 1.0 null Usher syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.873 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4988 A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.35312 IGHMBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92427 GSE216147_0_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Ensemble_gene_ID_MYC Rummagene Transcription Factor Associations 2026 1.0 null FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HMC18 CCLE Cell Line Gene CNV Profiles 1.0 1.39918 Autosomal recessive nonsyndromic deafness 16 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 ZNF598 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40169 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66323 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H2AX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96163 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040568 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210101,GSE210114_11_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874773 WDHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74242 Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.96673 Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22851 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210682_0_v_3_methadone_human RummaGEO Drug Perturbation Signatures 1.0 null NAA60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49021 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57388 Myosin XV complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.613 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11981 BT474 CCLE Cell Line Gene CNV Profiles -1.0 -2.03857 Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEG01 CCLE Cell Line Gene CNV Profiles -1.0 -1.71202 influences GeneRIF Biological Term Annotations 1.0 null GSE139975_3_v_0_rnf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Post-translational modification: synthesis of GPI-anchored proteins Reactome Pathways 2024 1.0 null Auditory vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.185 Cerebral folate receptor alpha deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.611 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840376 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9506 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null plasma membrane GO Cellular Component Annotations 2015 1.0 null JUND-26020271-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null EHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90618 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8691 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7192 SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_9752_KO_Rnf20/Rnf40_SRP228497 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.8362 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1096 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null FUBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10576 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25324 PPP1R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83196 Cogan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.629 Ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.777 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66879 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.09764 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00071 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.802385 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.5155 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26303 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55182 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4769 EXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51586 Microvillus membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.349 HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.7699 Stereocilia coupling link COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.802 Outer hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.697 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50379 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8745 HCCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11647 ERCC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60649 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Benign paroxysmal positional vertigo DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.398 interleukin-28 receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 Autosomal recessive nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.648 E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5369 abnormal membranous labyrinth morphology MPO Gene-Phenotype Associations 1.0 null UBE2J1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24784 Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE255432_4_v_0_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066908 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.2793 CTCF ENCODE Transcription Factor Targets 1.0 null ZNF160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13897 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stereocilium bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.533309 LDL cholesterol levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8123 MROH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87035 BT20 CCLE Cell Line Gene CNV Profiles -1.0 -1.98089 elements GeneRIF Biological Term Annotations 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.78478 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM74B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7395 SIRT4_KO_GDS4823_30_mouse_hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null extracellular region part GO Cellular Component Annotations 2015 1.0 null abnormal nervous system electrophysiology MPO Gene-Phenotype Associations 1.0 null SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7536 ENDOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82452 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83634 ZNF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18285 PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1599 CCLE Cell Line Gene CNV Profiles -1.0 -2.3514 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896687 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2111 LRPPRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98526 Autosomal recessive nonsyndromic deafness 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.472 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9888 Autosomal recessive nonsyndromic deafness 79 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.157 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.49606 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0394 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063416 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041174 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041589 Autosomal dominant nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.399 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane GeneRIF Biological Term Annotations 1.0 null CLDN1_OE_GDS3510_393_human_CL1-5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null abnormal cochlear labyrinth morphology MPO Gene-Phenotype Associations 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976602 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -1.56489 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2786 SIX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91708 abnormal scala media morphology MPO Gene-Phenotype Associations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TQ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5296 DUX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5201 CLDN1_OE_GDS3510_31_human_CL1-5 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Autosomal dominant nonsyndromic deafness 22 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.426 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27364 SNU1033 CCLE Cell Line Gene Expression Profiles -1.0 -1.70524 clinical modifier GWASdb SNP-Phenotype Associations 1.0 0.358325 Erythrokeratodermia variabilis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.253 posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.893592 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.896007 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNAJC2 ChEA Transcription Factor Targets 1.0 null PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.97259 A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_1day-MOI-10^4_None_GSE37572 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.54655 Jacobsen Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.311 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7345 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870847 PPP1R1A_KO_GDS1920_708_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20375 GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.305 TMK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.995856 KCIMOH1 CCLE Cell Line Gene Expression Profiles 1.0 2.07105 extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.421604 496100634_HIP_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.05409 GSE180200,GSE180201_5_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null CHIME syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03292 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5632 FOXA2 ChEA Transcription Factor Targets 1.0 null Connexin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.864 enlarged tectorial membrane MPO Gene-Phenotype Associations 1.0 null E2F7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88793 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.888296 FAM222B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43542 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.16978 SET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8673 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.434 collagen trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.358609 Hmgn1_KO_GDS5010_407_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827786 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.68047 Vestibular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.31 Usher syndrome type 1G DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.326 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04836 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2501 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.7893 GSE152699,GSE152723_0_v_1_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1436 CCLE Cell Line Gene CNV Profiles 1.0 1.33286 MIER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92521 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.837424 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0394 Metabolic dysfunction-associated steatotic liver disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 GSE226249_2_v_1_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null CHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36837 HNF4A ChEA Transcription Factor Targets 1.0 null anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39871 membrane part GO Cellular Component Annotations 2015 1.0 null RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5536 DCLRE1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80273 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907515 496100471_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10138 GSE224556,GSE224557_6_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2BC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79144 Autosomal recessive nonsyndromic deafness 35 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.23 MYC_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null CYP51A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5432 USP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09168 abnormal hearing physiology MPO Gene-Phenotype Associations 1.0 null MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20531 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1893 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837355 NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -1.78669 Axon cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.692 C3A CCLE Cell Line Gene Expression Profiles 1.0 3.40795 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-MYC_UP_V1_UP-Gene_name_MYC Rummagene Transcription Factor Associations 2026 1.0 null amniocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.635572 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0535 ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 Hatching liquid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.515 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890142 LRRC26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03151 nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.561728 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.94897 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Duodenum Mucosa Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.892779 GAMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58247 OVCAR4 CCLE Cell Line Gene CNV Profiles 1.0 1.8425 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.412771 POLR2A ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01386 Egg coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.989 Tricellular tight junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.635 SIRT4_KO_GDS4823_22_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76946 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.644001 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00601 PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null IRAK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51212 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55796 SESN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93288 GSE226249_2_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE154337_0_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null recurrence GeneRIF Biological Term Annotations 1.0 null Scolopale cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.586 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8573 CALCOCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39741 Congenital hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF21-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PM20D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15428 SENP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0266 Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr10_112288347_T_A_b38 GTEx eQTL 2025 1.0 1.68683 Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U178 CCLE Cell Line Gene CNV Profiles -1.0 -1.33095 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.926 Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48187 Liver GTEx Tissue Gene Expression Profiles 2023 1.0 2.55369 enlarged vestibular aqueduct DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.19704 chr10_112231153_G_T_b38 GTEx eQTL 2025 1.0 1.92663 Aspartate aminotransferase levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.9 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 Plantlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.323 TCF7L2-21901280-H4IIE-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pollen wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.627 MDAMB436 CCLE Cell Line Gene CNV Profiles 1.0 1.87399 proteinaceous extracellular matrix COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5939 Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102870_7_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.441042 extracellular region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.299569 extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null GSE160373_1_v_4_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.662 Dendritic growth cone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.574 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8379 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0149 outer hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.32913 anchored component of membrane GO Cellular Component Annotations 2015 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null Usher syndrome type 2D DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.914 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fetus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07626 Auditory capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.63 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09039 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IS-01A-21R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2H5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76924 throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.261964 FLI1-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6736 Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.460401 HES4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66291 496100444_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54579 Autosomal recessive nonsyndromic deafness 48 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115 PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_UP_MYC Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904761 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7944 GP2D CCLE Cell Line Gene Expression Profiles 1.0 1.42648 abnormal cochlear nerve compound action potential MPO Gene-Phenotype Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 29 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.456 AR ChEA Transcription Factor Targets 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02774 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837969 UBE2H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58068 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904761 Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9518 anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17521 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09075 SPI1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE165274_1_v_2_poldip2_mouse RummaGEO Gene Perturbation Signatures -1.0 null YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.63569 thyroid GTEx Tissue Gene Expression Profiles 1.0 1.38145 SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14182 Autosomal recessive nonsyndromic deafness 57 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.152 9+2 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.912 Wolfram syndrome 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 Autosomal dominant nonsyndromic deafness 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.632 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.03235 adenocarcinoma GeneRIF Biological Term Annotations 1.0 null inner hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.634762 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.4125 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null RARB-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.48298 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.435 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42338 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043705 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.062665 BCL11A_01_09 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60082 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4124 abnormal distortion product otoacoustic emission MGI Mouse Phenotype Associations 2023 1.0 null OXCT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52027 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7095 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.217 Autosomal recessive nonsyndromic deafness 8 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 Cochlear duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.77 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25866 NR5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47136 Johnston's organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.291 BAG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45307 ANTKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47012 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF21-23034159-E13-GONADS-RAT ChEA Transcription Factor Targets 2022 1.0 null Vestibular labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.821 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.997148 ARL2BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67186 Middle ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.585 water vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.613764 Alanine transaminase levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 chronic fatigue syndrome GWASdb SNP-Disease Associations 1.0 0.564734 sub-surface cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.75 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vestibular sensory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.034 ACY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54119 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44726 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stereocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.765 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7487 Sensory dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.419 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040892 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9853 GSE145476_2_v_3_hopx_mouse RummaGEO Gene Perturbation Signatures 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.97627 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amnion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274394 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A7U0-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pendred Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.092 LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null WM115 CCLE Cell Line Gene CNV Profiles -1.0 -1.47728 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36615 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7627 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.0959 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00749 KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -1.8124 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null TCF7L2 ChEA Transcription Factor Targets 1.0 null GSE138672_0_v_1_rabgef1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19547 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-GC-1B COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20809 NFYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3994 NFE2L2_KO_GDS514_699_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8317 GSE226249_2_v_7_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.463905 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064281 ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19547 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48379 inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72137 GSE210101,GSE210114_7_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Cochlea TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.828 vestibular labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.74925 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2367 SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.658049 RPE1SS48 DepMap CRISPR Gene Dependency 1.0 2.8899 JHH2 CCLE Cell Line Gene Expression Profiles 1.0 2.49092 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3863 AR-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MES-SA COSMIC Cell Line Gene Mutation Profiles 1.0 null Inherited metabolic disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 GSE181959_1_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null Cell hair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.924 HIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51433 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Neuromast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.459 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36615 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3781 Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TSC22D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69558 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74411 Weissenbacher-Zweymuller syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.357 MESSA CCLE Cell Line Gene Expression Profiles 1.0 1.42632 NCI-H1975 COSMIC Cell Line Gene Mutation Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.499615 Liver disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08468 Autosomal recessive nonsyndromic deafness 30 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.063 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11655 synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.070538 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5122 H2AFZ ENCODE Transcription Factor Targets 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36364 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neuroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.27471 inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.09797 Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.585 Hypolemmal cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.743 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4583 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.256 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0651 GSE202434,GSE202438_2_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.05571 GSE149264,GSE149267_2_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4965 MDAMB415 CCLE Cell Line Gene CNV Profiles 1.0 1.71422 C10 DepMap CRISPR Gene Dependency 1.0 2.07553 RARA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.94111 absent Hensen stripe MGI Mouse Phenotype Associations 2023 1.0 null thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.284607 TCF21-23034159-E13_GONADS-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null SH3BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59085 abnormal action potential MPO Gene-Phenotype Associations 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.491 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224556,GSE224557_8_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5938 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null proteinaceous extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.321575 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00778 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41351 A1207 CCLE Cell Line Gene CNV Profiles 1.0 1.97593 Inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.459 Stereocilia tip link COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.808 Autosomal recessive nonsyndromic deafness 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.804 abnormal otoacoustic response MPO Gene-Phenotype Associations 1.0 null PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.134 MLKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83276 GSE205550,GSE205552_2_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18852 LHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96605 1221 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.066 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01308 Autosomal recessive nonsyndromic deafness 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.715 Autosomal recessive nonsyndromic deafness 49 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.488 BE2M17 DepMap CRISPR Gene Dependency 1.0 4.77691 KPNRTBM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.42382 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null acetaminophen_homo sapiens_gpl6244_gse27420 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DNAJC2-21179169-NT2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abnormal tectorial membrane morphology MGI Mouse Phenotype Associations 2023 1.0 null cochlear duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.72583 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2898 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981705 KHDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57491 NFKBIZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64551 HEPG2 CCLE Cell Line Gene Expression Profiles 1.0 2.24998 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.071 HT55 DepMap CRISPR Gene Dependency 1.0 2.90713 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SKNMC CCLE Cell Line Gene CNV Profiles -1.0 -1.42846 AIFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54051 FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MED13L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47573 soft body part TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461852 Lysosomal storage disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 Autosomal dominant nonsyndromic deafness 65 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.445 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.6408 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98821 GSE188870,GSE188871_4_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.7879 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.943547 BT549 CCLE Cell Line Gene CNV Profiles -1.0 -1.34038 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9765 Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LDLRAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54042 ZNF43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20004 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.56491 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP8 CCLE Cell Line Gene CNV Profiles -1.0 -1.74301 EVSAT DepMap CRISPR Gene Dependency 1.0 4.44103 Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8142 hair-cell stereocilium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.963 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.70123 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16124 Water vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.103 ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06414 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC4 CCLE Cell Line Gene Expression Profiles 1.0 2.33069 MSMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36099 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.49839 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24961 WWC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76183 TAF6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.286 MAPK8IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01134 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.9248 ZBTB7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73625 17660535-TableS4c GeneSigDB Published Gene Signatures 1.0 null HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910936 Autosomal recessive nonsyndromic deafness 113 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.554 hypoparathyroidism-deafness-renal disease syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.497 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.02829 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 63 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9204 Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9316 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.86082 GSE226249_5_v_7_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.10864 neurological GAD High Level Gene-Disease Associations 1.0 0.293278 betatectorin GeneRIF Biological Term Annotations 1.0 null ZNF771 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84775 ELOVL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15086 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.67923 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72087 actin-based cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.285 SERPINB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19324 order GeneRIF Biological Term Annotations 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.032217 FSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95183 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30802 autosomal dominant nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.44869 Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.69621 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stria vascularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.144 FAM53B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98029 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.852525 RAD51AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89282 VMRCRCW CCLE Cell Line Gene Expression Profiles 1.0 1.40985 sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.15496 Modiolus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.066 ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00632 Rootlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.545 UBAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75721 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042574 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.5534 KLF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86836 ESET-19884257-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Thyroid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2712 chronic GWASdb SNP-Phenotype Associations 1.0 0.481126 Usher syndrome type 1D DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.023 KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.42487 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29788 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.80462 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Usher syndrome type 1C DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.629 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3289 ORAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40333 NB7 DepMap CRISPR Gene Dependency 1.0 2.09297 abnormal cochlear frequency tuning MPO Gene-Phenotype Associations 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07393 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC12008806-mmc13.xlsx-ST12-Unnamed_36_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.985031 PMC7898758-40168_2020_994_MOESM4_ESM.xls-STAT1_target_genes-Gene_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null 496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13801 stereocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.551012 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69157 HOXA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21519 USH2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.063 PSIP1_02_99 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.6477 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 102 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.349 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 1.86247 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6041 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03898 colorectal GeneRIF Biological Term Annotations 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.0773 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8591 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0977 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41907 Bony labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.489 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.67152 ZNF343 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92054 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.668413 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null enhanced cochlear frequency tuning MGI Mouse Phenotype Associations 2023 1.0 null Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.779 IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.51705 GSE166004_3_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXP2 ChEA Transcription Factor Targets 1.0 null Autosomal recessive nonsyndromic deafness 23 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.465 Dlx5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.6453 Muenke Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.398 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.498048 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4075 TCFL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68842 INF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09865 single GeneRIF Biological Term Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80N-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226249_0_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null UQCR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66002 GSE221327_5_v_2_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null GSE221327_4_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null CBFbeta_Deficiency_GDS3577_557_mouse_Regulatory T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910068 CREB1_01_194 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.47364 HTRA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.507 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043366 voltage-gated potassium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.9 abnormal ear morphology MPO Gene-Phenotype Associations 1.0 null POMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39897 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.55043 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04033 ceacam16 GeneRIF Biological Term Annotations 1.0 null Autosomal recessive nonsyndromic deafness 74 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 abnormal distortion product otoacoustic emission MPO Gene-Phenotype Associations 1.0 null LIN37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35285 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.938916 PDCD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.0363 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.964522 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.84226 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.903172 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20022 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0394 KM12 CCLE Cell Line Gene Expression Profiles 1.0 1.67657 KLF15_Deficiency_GDS2687_649_mouse_Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5336 GSE94011_0_v_3_pias3_mouse RummaGEO Gene Perturbation Signatures -1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE167956_1_v_0_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1053 Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226249_0_v_7_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4906 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.36309 GSE183271_1_v_0_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.212271 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 109.085 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40268 phycobiont TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.385896 Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.40976 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.106 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.288668 abnormal tectorial membrane marginal band morphology MGI Mouse Phenotype Associations 2023 1.0 null microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.167125 abnormal tectorial membrane striated-sheet matrix morphology MGI Mouse Phenotype Associations 2023 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF334 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7893 Kidney Chromophobe_KICH_TCGA-KM-8442-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Clouston syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32443 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.35038 PRECLH CCLE Cell Line Gene Expression Profiles -1.0 -1.50581 CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56081 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.75129 FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Labyrinthine zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.588 chr10_112286647_T_G_b38 GTEx eQTL 2025 1.0 2.15294 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.962261 GSE210885_2_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 25 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.387 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.16978 ZIC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73269 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973271 SACS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94904 higher GeneRIF Biological Term Annotations 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89972 saccule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.599273 Steatotic liver disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.656 SNAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55154 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3962 PPARG-20887899-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.8747 FAM89B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7983 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null Cochlear labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.158 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null STN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66008 DKMG CCLE Cell Line Gene CNV Profiles -1.0 -1.63029 SNU520 CCLE Cell Line Gene Expression Profiles -1.0 -1.47169 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9419 ZNF205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12763 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3199 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.6672 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.916156 Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.743 polymorphism GeneRIF Biological Term Annotations 1.0 null Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.652 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.72743 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.928573 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40324 GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 39 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.197 KLF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41124 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08043 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.832121 CUL4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.45047 SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Usher syndrome type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09805 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907515 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14457 midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.093312 SOX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5078 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950646 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.566 HS936T CCLE Cell Line Gene Expression Profiles 1.0 1.52288 Lower tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.271 other GeneRIF Biological Term Annotations 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6644 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4697 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33804 MZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26474 RMND5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71812 KP2 CCLE Cell Line Gene Expression Profiles -1.0 -1.80948 Stomach GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.55682 PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null POU5F1-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59472 DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null JHU-011 COSMIC Cell Line Gene Mutation Profiles 1.0 null ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Downstream_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null Minor Salivary Gland GTEx Tissue Gene Expression Profiles 2023 1.0 1.68966 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UGT3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4249 ARMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66715 Brain Lower Grade Glioma_LGG_TCGA-DU-6408-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Autosomal recessive nonsyndromic deafness 12 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.78 Hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.625 Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null Myosin VI complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.501 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75587 GAK COSMIC Cell Line Gene Mutation Profiles 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04836 SREBF1 ChEA Transcription Factor Targets 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963177 U266B1 CCLE Cell Line Gene Expression Profiles 1.0 1.47944 filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.385896 Columnar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.261 NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0791 Zona pellucida domain, conserved site InterPro Predicted Protein Domain Annotations 1.0 null outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.977371 TT2609C02 CCLE Cell Line Gene Expression Profiles -1.0 -1.57878 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01913 GSE226249_0_v_6_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null TDRD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57512 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 form GeneRIF Biological Term Annotations 1.0 null PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null KLF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27464 hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.50669 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adipose - Visceral (Omentum) GTEx Tissue Gene Expression Profiles 2023 1.0 3.24492 abnormality of immune serum protein physiology GWASdb SNP-Phenotype Associations 1.0 0.69439 Autosomal recessive nonsyndromic deafness 36 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.59 FOXA2-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNPNAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14977 Autosomal recessive nonsyndromic deafness 21 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.14 Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.102876 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14647 Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RDH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32214 Microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.364 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.0245 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ribbon synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.501 U138MG CCLE Cell Line Gene Expression Profiles -1.0 -1.64814 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 8305C CCLE Cell Line Gene Expression Profiles -1.0 -1.50435 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03164 Hyperplasia CTD Gene-Disease Associations 1.0 1.09963 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.930367 syndrome GWASdb SNP-Disease Associations 1.0 0.342736 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38889 Exocytic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.535 496100385_TCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46109 TNFSF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81752 MAML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24835 Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Unconventional myosin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.377 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03335 Stereocilium tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.672 abnormal ear physiology MPO Gene-Phenotype Associations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I4-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846235 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.955895 NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.62155 Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07159 Metabolism of proteins Reactome Pathways 2024 1.0 null Small Intestine - Terminal Ileum GTEx Tissue Gene Expression Profiles 2023 1.0 2.8993 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures 1.0 null AP2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82695 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149124,GSE149128_2_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4849 ITGA7_OE_GDS3209_142_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.889 MDAMB361 DepMap CRISPR Gene Dependency 1.0 3.20201 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.348 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stickler syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1297 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SFR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78699 FOXA2-19822575-HEPG2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.231206 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.03375 Brain - Cortex GTEx Tissue Gene Expression Profiles 2023 1.0 2.38088 EFF-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.521 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78631 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8794 Smad4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.058 Cochlear ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.023 NUP35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31839 phospholipid-translocating ATPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.754 OVK18 CCLE Cell Line Gene CNV Profiles 1.0 1.33187 FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null PATU8988S DepMap CRISPR Gene Dependency 1.0 2.92797 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.32 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.32371 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054414 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3602 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer I of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42709 GSE171269_1_v_0_pioglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null abnormal inner ear morphology MPO Gene-Phenotype Associations 1.0 null physical GeneRIF Biological Term Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04389 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACN COSMIC Cell Line Gene Mutation Profiles 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0394 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07977 COLO205 DepMap CRISPR Gene Dependency 1.0 2.60858 REP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55643 FTSJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06946 Nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.743 OS-RC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.05894 Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1077 CCLE Cell Line Gene Expression Profiles -1.0 -2.1196 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.500761 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular matrix part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.318579 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.886497 Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.866536 MSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32543 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PRKCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49644 CCNO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13765 hearing/vestibular/ear phenotype MPO Gene-Phenotype Associations 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8687 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPE1SS6 DepMap CRISPR Gene Dependency 1.0 2.44424 MECP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.602 SW1116 CCLE Cell Line Gene Expression Profiles 1.0 1.89517 GSE221327_1_v_2_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ultraconserved GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Auditory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 Diabetic Neuropathy_Sciatic Nerve_GSE11343 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.6732 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.18762 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3874 Autosomal dominant nonsyndromic deafness 25 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null OVOL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42741 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.36699 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051866 basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10355 abnormal tectorial membrane morphology MPO Gene-Phenotype Associations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CG-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29617 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13175 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.963177 supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.648938 cell part GO Cellular Component Annotations 2015 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.286 MLLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94874 MIS18BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08338 spiral organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.75024 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHCHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77288 MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.727 BRPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44622 JUN-26020271-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures -1.0 null Vestibular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.821 Vestibular hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.75 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052547 PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1 Rummagene Transcription Factor Associations 2026 1.0 null enhanced cochlear frequency tuning MPO Gene-Phenotype Associations 1.0 null MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.916156 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.90177 Autosomal recessive nonsyndromic deafness 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.866 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7883 ISTMES2 CCLE Cell Line Gene CNV Profiles -1.0 -1.33403 STAT3 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tympanum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.054 nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.36074 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hepatobiliary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7060-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null icSARS CoV_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.778489 Palmoplantar keratosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39924 Calyx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.22 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33423 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052582 Autosomal recessive nonsyndromic deafness 93 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.332 Total cholesterol levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.922185 cellular_component GO Cellular Component Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP2-21765815-NEURO2A-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.171785 Semicircular canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.928 CLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92089 ACSBG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79752 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.337 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PK59 CCLE Cell Line Gene CNV Profiles 1.0 1.95002 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31084 abnormal cochlea morphology MPO Gene-Phenotype Associations 1.0 null SUM149PT DepMap CRISPR Gene Dependency 1.0 2.21452 PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null Lateral part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.751 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LRRC58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94224 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.839304 HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.582645 TEAD4-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null structures GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMILIN complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.517 PFAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94744 Saccule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.035 Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67655 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7201 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37575 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.06111 ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0168 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77973 Post-translational protein modification Reactome Pathways 2024 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 77 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.231 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SREBP1-19666523-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE180200,GSE180201_12_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null RERFGC1B CCLE Cell Line Gene CNV Profiles 1.0 3.24327 KANK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48995 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.146 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.46645 GSE132759_4_v_5_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.97981 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07751 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.9627 TRIM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35081 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927061 impaired hearing MGI Mouse Phenotype Associations 2023 1.0 null Townes-Brocks syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.339 liver HPA Tissue Gene Expression Profiles 1.0 1.52243 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904761 TRMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93359 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7964 AR-19668381-PC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZSCAN22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79973 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.918 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7752 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16124 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.942 extracellular matrix GO Cellular Component Annotations 2015 1.0 null Meniere's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.004 HLA-C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97213 inner ear vestibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.335 MLLT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68751 PGAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57155 MBD3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05735 HPAC CCLE Cell Line Gene CNV Profiles 1.0 1.46168 RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84391 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3571 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Secretory granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.534 PLOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68781 cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.885355 Ubisch body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.516 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null HSFX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22766 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4405 Triglyceride levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.3 SUM159PT DepMap CRISPR Gene Dependency 1.0 3.5194 olfactory tubercle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895569 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.811 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.231 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Spiral organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.765 ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55007 NCIH2141 CCLE Cell Line Gene Expression Profiles -1.0 -2.01165 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8009 OCILY3 CCLE Cell Line Gene Expression Profiles 1.0 1.44139 Relapsing polychondritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7498 GSE221327_1_v_11_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3103 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7262 GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null RKO-E6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2267 MXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45704 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.419 GSE155800_1_v_0_imatinib_human RummaGEO Drug Perturbation Signatures -1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.18067 extracellular region LOCATE Curated Protein Localization Annotations 1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6385 HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.429 Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1475 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.6018 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.513 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00778 DNAJC2-21179169-NT2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 deferoxamine_homo sapiens_gpl13497_gse30774 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null THP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.98385 Triglyceride levels in current drinkers GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 Inner ear vestibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.378 AGS COSMIC Cell Line Gene Mutation Profiles 1.0 null POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2346 VMRCLCD CCLE Cell Line Gene Expression Profiles -1.0 -3.38921 Autosomal recessive nonsyndromic deafness 61 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.297 SETBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15779 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7478 GOLGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56514 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.893592 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null HCT116 CCLE Cell Line Gene CNV Profiles 1.0 1.46899 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90183 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15158 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55344 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.736 PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13 Rummagene Transcription Factor Associations 2026 1.0 null inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15413 NFI-21473784-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SW756 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-157 COSMIC Cell Line Gene Mutation Profiles 1.0 null thyroid gland HPA Tissue Gene Expression Profiles 1.0 1.30296 NET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93778 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.857439 496100446_TCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.746 HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2325 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22682 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.653 EB1 CCLE Cell Line Gene Expression Profiles 1.0 1.69267 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836075 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4207 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3037 foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.448355 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kinocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.912 Cell surface COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE146072_0_v_1_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.73424 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86585 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5669 Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31851 GSE160373_6_v_4_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null