association	dataset	threshold value	standardized value
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19879
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71166
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K53748177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33305
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62905
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.74047
3123_FNBP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.529151
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9445
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949405
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20956
7169_RBM28_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.946894
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64489
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04885
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15005
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98383
PEA1	DepMap CRISPR Gene Dependency	1.0	2.93712
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17948
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	0.930999
abnormal male reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.843077
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.926336
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59214
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19455
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.12807
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
NSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65129
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654229
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
BRD-K27807043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04527
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047004
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2492
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07046
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26269
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24039
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91576
18199535-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K96778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10335
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11732233-mmc1.pdf-426-ZNF254_ZNF254	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12178937-mmc6.xlsx-L_MAFF_KDvsL_C_deg_all-gene_name_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2674
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
Microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.49652
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35011
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97147
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60992
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10186
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.48253
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68674
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
ZNF845	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96376
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
KLHDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24313
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41126
CEP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61051
microtubule	GO Cellular Component Annotations 2015	1.0	null
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05957
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885241
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59146
BRD-K23393260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01075
6219_PES1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625121
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89979
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877744
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.810433
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	0.930999
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27257
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15416
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
BRD-K13472433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39109
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865336
MKN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70492
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74732
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85768
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7631
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.40117
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLOC1S4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33878
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50886
HKA1	DepMap CRISPR Gene Dependency	1.0	2.4458
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	1.75609
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97617600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74148
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02548
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.44616
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00178
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42162
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.944664
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0107
BRD-K75904236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17096
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78856515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49862
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42071
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834591
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12609
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03785
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.46189
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966772
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cilium movement	GO Biological Process Annotations 2025	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890163
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38125
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.61843
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10243
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10194
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82577
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955128
vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.747515
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30796
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12374
Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.10527
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4634-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0672
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97888
Leber congenital amaurosis 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.82778
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.887761
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19004
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87217
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.44671
Midbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.769
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7255
UQCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77524
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37024
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34738
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947641
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00819
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NCIH2347	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03176
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97222
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.541
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67834
Perturb_6568_KO_Ywhaz_SRP056013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7174
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27615
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46276
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7402
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058909
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.23371
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74055
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83062
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.735796
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.90982
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47564
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14336
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.6755
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4102-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.384
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
cilium movement involved in cell motility	GO Biological Process Annotations 2023	1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08746
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22606
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4807-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064238
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0291
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17021
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90861
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950509
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37705
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84769
HUT78	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57786
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03698
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830036
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K21996189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65767
AGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34029
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28745
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33436
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046028
SIN3B	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35709
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
A101D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22654
BFTC-905	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63039
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1883
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17983
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.35874
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52741
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.818
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51408
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07643
SAMD14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22437
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97410356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76785
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74121
cell-substrate junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.419
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.819
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90579
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
Dorsal lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.01187
NCIH684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61707
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16652
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909328
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.935293
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15631
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGO1_02_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894118
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2366
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07387
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE254770_3_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
5023_MFN2_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.523524
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07482
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053261
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2698
BRD-K37386363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94273
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59991
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862019
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49418
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897262
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
APBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98765
HOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24202
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05408
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32589
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1147
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87207
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049322
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
18032706-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.40401
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53618
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01334
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
positively	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CREB1_01_04	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.47761
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.59274
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.768
clinical	GeneRIF Biological Term Annotations	1.0	null
EPHA7	MSigDB Cancer Gene Co-expression Modules	1.0	null
Perturb_11485_KO_Mir183_SRP107957	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.46286
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92997
FUS_02_155	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.53605
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.90466
BRD-K31204557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5064
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30381
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HTK	CCLE Cell Line Gene Expression Profiles	-1.0	-3.24738
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06526
cilium-dependent cell motility	GO Biological Process Annotations 2025	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24715
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15131
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.640803
Velocardiofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
BRD-K01367715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20193
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870291
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992038
BRD-K38831170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20443
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.880065
SAOS2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51043
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K43326597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76139
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73704
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040411
BRD-K61092554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47008
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43474
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07584
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24788
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168847
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6728
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K85292767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16203
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00942
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55374
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1111
actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0596
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20462
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938505
BRD-K75596743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2811
cell motility	GO Biological Process Annotations 2015	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.43877
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06343
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39357
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03474
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54548
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.017
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02931
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.428678
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cilium movement	GO Biological Process Annotations 2023	1.0	null
BRD-K16276539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04667
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal-hepatic-pancreatic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67467
Fibrosis	CTD Gene-Disease Associations	1.0	1.15122
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24624
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
catsper	GeneRIF Biological Term Annotations	1.0	null
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78702
SSB_02_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.10434
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13016
TARDBP_02_129	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2452	DepMap CRISPR Gene Dependency	1.0	3.41138
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44195
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69379
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.21322
MKN45	DepMap CRISPR Gene Dependency	1.0	3.38828
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02632
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.43217
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64082
JMSU1	CCLE Cell Line Gene Expression Profiles	1.0	1.95727
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62304
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21243
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	2.332
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24444
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TC138	DepMap CRISPR Gene Dependency	1.0	2.21329
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.917464
GSE196540,GSE196542_4_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63806
midbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365095
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55141
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58415
TRIM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45426
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54712
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73737
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843409
BRD-K60144139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2212
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955128
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08769
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41999
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.933727
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048451
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20124
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58072
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.353
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50148
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25782
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07256
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61352
BRD-K14181473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18833
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.980217
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87102
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36185
6062_PAPOLA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506862
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
description	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.60473
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512311
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861257
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02116
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42388
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98032
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12142
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2699
PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824285
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56784
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17133
outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.51469
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92411
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405176
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887271
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.885096
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.029
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	1.60775
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02342
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909022
BRD-K00057967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23421
NCCIT	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC12178937-mmc6.xlsx-L_MAFF_KDvsL_C_deg_all-gene_id_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32718856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02064
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7308
BRD-K47001624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48378
KPNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.257
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55627
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6125
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cilium assembly	GO Biological Process Annotations 2023	1.0	null
BRD-K29420358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43001
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24445
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.6
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21284411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49857
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65268
OCIAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42986
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52418
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13407
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03196
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABARAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61522
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51643
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80795
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.75643
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15729
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20344
Perturb_17816_KO_Nr1d1_ERP120331	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79853
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral sucker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
abnormal germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K18245187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88024
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.97354
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51377
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-2.05169
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2793
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4828-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A3-KAW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43971
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70023
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06189
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.185
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
OC315	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60291
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16924
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
microtubule associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.576747
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059473
KLE	DepMap CRISPR Gene Dependency	1.0	2.07247
BRD-K61877191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93594
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MNAT1_Deficiency - Ablation_GDS2561_689_mouse_Heart - 2 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
Mesothelioma_MESO_TCGA-MQ-A6BQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871256
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.192
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20488
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
Asthenozoospermia	DisGeNET Gene-Disease Associations	1.0	null
asthenozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40328
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SBC-5	GDSC Cell Line Gene Expression Profiles	1.0	1.54359
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44938
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
abnormal mucociliary clearance	MPO Gene-Phenotype Associations	1.0	null
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.602
KDM5A	ENCODE Transcription Factor Targets	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	1.47216
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4084
etiocholanolone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02572
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053115
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5879
HUT102	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01196
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09131
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44177
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5357
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51635
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08926
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49815
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62176
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.187333
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07726
TBP	ENCODE Transcription Factor Targets	1.0	null
PMC3507169-supp_bio.20121594_bio.20121594-tableS1.pdf-17-BAZ2B_BAZ2B	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831508
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25672
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.62336
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878989
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal cilium morphology	MPO Gene-Phenotype Associations	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.61523
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.29372
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77197
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982716
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34457
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20822
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	2.33909
HER2_OE_GDS4763_331_human_MCF10A - immortalized breast epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
NCIH1435	CCLE Cell Line Gene Expression Profiles	1.0	1.75183
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25739
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811473
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34949
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44287054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27797
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.29703
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26932
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59434
abnormal tracheal ciliated epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6412
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89063
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84199
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19885
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35245
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.82452
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82697
16081686-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04501
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04134
GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K61655210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17306
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83658
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1764
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.867787
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77831
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97741
rostral group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931414
first	GeneRIF Biological Term Annotations	1.0	null
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.583
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.779
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cilium assembly	GO Biological Process Annotations 2025	1.0	null
NUDT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54411
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COR-L88	GDSC Cell Line Gene Expression Profiles	1.0	2.28897
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33313
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0137
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01911
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23452
TBP	ChEA Transcription Factor Targets	1.0	null
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32519
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01237
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41316
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60392
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57564
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846272
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
DLX5_OE_GDS4577_345_mouse_Otic vesicle derived 2B1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82681
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62299
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22063
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26762
BRD-K35288606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19668
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16484322-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
cilium movement involved in cell motility	GO Biological Process Annotations 2025	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73562260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07081
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.44763
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.56102
BRD-K79184750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9012
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28111
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25334
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24207
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
axoneme part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15723
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23122
cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_macaque_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.57298
fleroxacin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98159
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11776
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13493
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	1.37332
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPK_02_136	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.9542
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48226
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863506
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.526441
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355198
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03142
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MAP3K14	MSigDB Cancer Gene Co-expression Modules	1.0	null
SW1573	DepMap CRISPR Gene Dependency	1.0	2.01641
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.15104
cellular protein complex assembly	GO Biological Process Annotations 2015	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48778
HDAC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03246
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAPC	GDSC Cell Line Gene Expression Profiles	1.0	2.37136
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inner acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.40614
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59645
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
Epididymis disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
SYCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50365
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62666
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.994
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0977
single-organism process	GO Biological Process Annotations 2015	1.0	null
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
NCIH508	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64916
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SW962	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15428
Perturb_13166_Mut_Trp53_ERP108431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61952
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
DOV13	DepMap CRISPR Gene Dependency	1.0	2.44211
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53695
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12982
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.80582
cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01451
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954201
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20808
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63464
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41293
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73138
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
C84	DepMap CRISPR Gene Dependency	1.0	2.36304
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10287
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30555
5659_NGDN_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.03362
EZH2	ENCODE Transcription Factor Targets	1.0	null
Lung-lung ciliated cell	Tabula Sapiens Gene-Cell Associations	1.0	7.73835
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31807
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44907
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828977
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15946
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25555
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87140555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00057
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07152
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76489
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936891
Filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40041
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15415
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.604981
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77234
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03173
MFE280	CCLE Cell Line Gene Expression Profiles	1.0	1.56824
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	3.78921
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31806
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10909
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.29085
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.984486
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
HES3_KO_GSE64449_186_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80952
BRD-K04508260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28585
Sperm end piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.652
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932352
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27577
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.01663
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971454
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866756
organelle assembly	GO Biological Process Annotations 2023	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83533725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6417
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61737
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.977
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.723
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07599
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855526
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43891
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58687
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3129
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55397
small intestine	HPA Tissue Gene Expression Profiles	-1.0	-0.904326
abnormal sperm physiology	MPO Gene-Phenotype Associations	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
6118_PCED1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542492
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21404
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06006
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20237
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
BRD-K72636868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8097
MDAMB231	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85874
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94394
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986758
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28969
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04823
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40315
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
TE9	DepMap CRISPR Gene Dependency	1.0	2.17587
asthenozoospermia	MPO Gene-Phenotype Associations	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00294
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23288
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.870459
Tektin	InterPro Predicted Protein Domain Annotations	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27813
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.65625
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924092
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41352
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18303
rectum	HPA Tissue Protein Expression Profiles	1.0	0.930999
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.36862
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70937
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38607
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18225
BRD-K83934572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01248
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72645
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43986
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7959
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56951
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
3872_HNRNPL_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642282
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
only	GeneRIF Biological Term Annotations	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.840977
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5180-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26383086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10413
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
SW620	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02802
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11394
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044579
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68753
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.857635
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18771
BRD-K09977699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2508
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Distal arthrogryposis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2598
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72714
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09419
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44277
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.199
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829288
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52041
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06311
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11578
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05755
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
bronchus	HPA Tissue Protein Expression Profiles	1.0	2.33909
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42539
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04332
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874906
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80393
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32131
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-410	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46926
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89582
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
motile cilium	GO Cellular Component Annotations 2015	1.0	null
WNT1	MSigDB Cancer Gene Co-expression Modules	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13271
CEBPB	ENCODE Transcription Factor Targets	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11867
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTUD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14525
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
SCC4	DepMap CRISPR Gene Dependency	1.0	2.42862
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.930999
CDK19_knockdown_148_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.08418
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21566
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-471-PAX6_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49129
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.44984
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99969
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.43508
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.36699
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
TE6	DepMap CRISPR Gene Dependency	1.0	2.61652
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.4482
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0758
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94722
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08332
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16734
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51602
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831508
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5276
BRD-K89471250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0965
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.897144
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86714
BRD-K80848948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07522
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88043
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02312
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40513
hairpin sperm flagellum	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31002
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24404
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
RNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93825
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5133
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07353
KP-N-YS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44083
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841656
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59603
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70275
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0876
Perturb_702_KD_SETDB1_SRP116954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.67806
Perturb_7898_KD_NCL_SRP337780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60384
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
BRD-K80298486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25085
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21406
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5517
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.65674
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14949
PA1	DepMap CRISPR Gene Dependency	1.0	2.07742
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K04803823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12866
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10651
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
DENND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91305
Retinitis pigmentosa 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.535
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097925
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69721
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
MXI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861951
BRD-K11643336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31154
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09111
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.071001
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42678
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.888195
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.942252
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36825
Perturb_8587_KO_Adnp_SRP063269	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.42879
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22813
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20311
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91836330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08969
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.751704
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35112
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03373
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93412
BRD-K70695911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62275
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91606
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06669
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976509
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964973
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
3776_HIST1H4A_ENST00000359907.3	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.580495
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840015
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-OTX1_OTX1	Rummagene Transcription Factor Associations 2026	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3764
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88737
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2346
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69356
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
succinate-CoA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.87764
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30024
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26224
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.1842
Her2_OE_GSE43730_683_human_MCF10A cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89876
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6192
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050843
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86919
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29066
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22108
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934273
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04197
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.913088
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21539
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01405
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29906
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75041866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27512
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	2.22328
JUND	ENCODE Transcription Factor Targets	1.0	null
abnormal respiratory motile cilium physiology	MPO Gene-Phenotype Associations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04775
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39208
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.24098
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15266
FLO1	DepMap CRISPR Gene Dependency	1.0	2.65804
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01537
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292616
A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65886
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3370-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056341
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.51
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.7981
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982643
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954201
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10348
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15456
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PTBP1_02_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24793
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
MYF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94761
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.39055
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
abnormal motile cilium physiology	MPO Gene-Phenotype Associations	1.0	null
SW780	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82347
ARNT_01_240	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64221
ACHE_OE_GDS891_241_mouse_Prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07223
BRD-K53094498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02513
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32824
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28066
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
abnormal sperm motility	MPO Gene-Phenotype Associations	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84795
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18532
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957504
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27484
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56583
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.523588
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09724
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862967
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61796560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25594
8MGBA	DepMap CRISPR Gene Dependency	1.0	2.06839
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
8738_TBL3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.551956
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.768
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outcome	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.954392
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056576
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Epididymitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
Bladder carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83675
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
MKN28	DepMap CRISPR Gene Dependency	1.0	4.0998
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	1.15178
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30711
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.686221
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
KLHL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68655
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85204
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
Perturb_6587_KO_Hira_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855526
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.726726
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999328
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.630576
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865251
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26247
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32092
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849027
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00498
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11189
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.906067
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988248
BRD-K81400584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38242
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989155
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.43508
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12589
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10322
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869924
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.908359
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.162546
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96333
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17809
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.876
18844975-Table1b	GeneSigDB Published Gene Signatures	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06038
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cilium organization	GO Biological Process Annotations 2023	1.0	null
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.86158
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11123
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2094
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.77
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25752
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1536
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
abnormal motile cilium morphology	MPO Gene-Phenotype Associations	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0112
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25792
BRD-K68823900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8121
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19862308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45281
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.746381
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.48689
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.791939
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43053
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8158
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936117
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950151
abnormal spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45785
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854046
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
NB4	CCLE Cell Line Gene Expression Profiles	1.0	2.25236
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76563
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7531
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13644
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14744
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30515
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.47795
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
2633_EN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.616938
KDM7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34307
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.76261
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
oxaliplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99802
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
5163_MPHOSPH10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570527
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
teratozoospermia	MPO Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.877103
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.66964
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.047
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4756
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.88025
Bardet-Biedl syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
GSE111660_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943565
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18214
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05464
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.29085
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07096
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.610778
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05076
BRD-K81706364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55339
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10699
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07832
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23125
BRD-K09597785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64782
adherens junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
LU-134-A	GDSC Cell Line Gene Expression Profiles	1.0	1.49136
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3163
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cilium	GO Cellular Component Annotations 2015	1.0	null
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07526
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60452
icsi	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Alevin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1601
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43547
dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.627761
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TMEM201	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67941
DMD_Deficiency_GDS2996_614_mouse_Cardiac muscles from 10.5-month (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04142
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45936
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03564
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.980217
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66115
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00283
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36412
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.39676
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50985
BRD-K43535770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17844
PMC9691391-7945884.f3.pdf-164-ENSG00000229809_ZNF688	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.044
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03168
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55896
U2904	DepMap CRISPR Gene Dependency	1.0	2.52893
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925917
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19337
abnormal tracheal ciliated epithelium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3854
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0719
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.769
DBH_KO_GDS4324_362_mouse_Embryonic heart  E10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924092
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.174125
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3781
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.735796
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36618
XPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30082
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
mRNA_FOXP1_21924763	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K14383477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12858
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11123
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77612
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.24341
T3M4	DepMap CRISPR Gene Dependency	1.0	3.07181
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.91993
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11123
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
TGIF2LX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0459
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940076
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40223
Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.48527
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55406
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K97638135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04495
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60981
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48783
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1273
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7948
BRD-K63829331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16713
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16408
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702717
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96054
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12369
6511_POGZ_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504139
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938226
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34395
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32956
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954201
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.966796
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69398
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27372
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11123
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2461
BRD-K22839533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30831
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07383
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15803
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64273
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29768655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80171
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50342
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.930999
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84001
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28904
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46966
2793_EXOSC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620914
ROS50	DepMap CRISPR Gene Dependency	1.0	2.47964
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70427
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	2.62116
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913413
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27555
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23775
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15527
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29281
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52834
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
abnormal respiratory motile cilium morphology	MPO Gene-Phenotype Associations	1.0	null
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74442
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94249
PrPC_KO_GDS4352_358_mouse_Developing hippocampus from FVB newborns (4.5-day-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.788
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
LP1	DepMap CRISPR Gene Dependency	1.0	2.10172
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.37592
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840342
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30942
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6083
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996231
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.633675
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75568
inferior temporal gyrus, right, bank of mts	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917316
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14253
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14449601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05589
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1304	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4796
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0737
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828605
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46408
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.254017
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16076
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02384
BRD-K68450812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25818
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5715
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATXN7L3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82286
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09314
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17353
nucleus	GO Cellular Component Annotations 2025	1.0	null
NFE2L2_02_174	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.26849
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
BRD-K84935903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33098
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831325
BRD-K70264850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0569
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52863
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11299
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10828
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841656
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_macaque_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7087
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01205
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73787
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52906
BRD-K73025852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37752
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27067
Axonemal microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3263
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.49296
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30687
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81335986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23327
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
Holt-Oram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.27177
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5074
DROSHA_02_145	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.83007
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0682
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIA1_KO_GSE54418_265_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.242076
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.176757
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12377
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8446
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909055
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal respiratory motile cilium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35958
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
BRD-K88369626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64241
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.806882
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53022
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59256
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.08613
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	2.10653
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01503
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12738
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21354
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77486
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K67830713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10932
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11334
since	GeneRIF Biological Term Annotations	1.0	null
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27338
A172	DepMap CRISPR Gene Dependency	1.0	2.51842
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840771
v91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214388
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96359
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.731442
BRD-K34825242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07389
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16273
ST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93631
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63739
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95500387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67687
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05418
Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.934
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
MAX::MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4286
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70434
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6678
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11885
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95171874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67946
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26687
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
10123_ZIC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642715
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RAB3A	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96822
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8014
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04598
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44455
BRD-K97337407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54045
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874601
PMC12176927-125_2025_6424_MOESM1_ESM.pdf-23-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85068
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EKVX	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51174
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04674
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9195
Centralspindlin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96859
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
KNS42	DepMap CRISPR Gene Dependency	1.0	2.20262
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25512
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49035
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.117
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36625
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13793
BRD-K45057266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70581
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.984838
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896222
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PITX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42503
parahippocampal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925618
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66127
abnormal respiratory motile cilium physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.08942
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40378
BRD-K89806367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00439
496100509_HIP_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00453
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20853
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.33739
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12169
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.19076
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8119
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25308
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21312
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.921706
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53577657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31479
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11285
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14822
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW156	DepMap CRISPR Gene Dependency	1.0	3.06832
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87871
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male infertility	MPO Gene-Phenotype Associations	1.0	null
Perturb_1848_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54204
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.35678
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63242
correlated	GeneRIF Biological Term Annotations	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19445
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961647
SOX9	ChEA Transcription Factor Targets	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0307
AMOTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01355
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99258
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15142
BRD-K48143921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40049
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919421
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MIST1_KO_GDS1731_758_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17297
5232_MRPL49_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.791925
BRD-K89891928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.166
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	2.16929
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25102
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MED23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42893
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29065
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04336
MRPL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92775
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	0.855703
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.06027
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02541
BRD-K87261428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63954
BRD-K17239874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21909
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38097
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
SLC30A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53585
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05168
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
GID8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7728
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.58215
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77272277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28212
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.16981
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16431
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
nb4	HPA Cell Line Gene Expression Profiles	1.0	2.32519
ZNF76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99499
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32909
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15548
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09444
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954201
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210655_3_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57867
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21419
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01546
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855526
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63225
BRD-K49526793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87137
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.6667
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72521
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.346
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cell-substrate adherens junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Orchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99069
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92793
focal adhesion	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80231
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955128
primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38428
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04695
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00266
hek293	HPA Cell Line Gene Expression Profiles	1.0	0.857293
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899786
microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
H3K9me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040637
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05708
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A2BAR_Deficiency_GDS3662_520_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05535
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02286
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.88624
BRD-K32214429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09006
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RXRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.278
BRD-K21450593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17535
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35858
A427	DepMap CRISPR Gene Dependency	1.0	2.34328
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8673
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77792
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45860594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17786
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.059
abnormal sperm axoneme morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
BAG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.877007
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.723
21205295-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964558
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04105
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31559
locomotion	GO Biological Process Annotations 2015	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985356
G401	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52211
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13032
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09209
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21834
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89001
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axonemal dynein complex assembly	GO Biological Process Annotations 2015	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	2.74738
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01297
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.34961
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96174
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897262
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.35021
GP2D	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12988
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.55138
JHH1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55611
COL18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552991
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11045
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00457
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
cilium-dependent cell motility	GO Biological Process Annotations 2023	1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00397
models	GeneRIF Biological Term Annotations	1.0	null
abnormal gametes	MPO Gene-Phenotype Associations	1.0	null
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68929
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.707
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.535
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01442
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86401
Perturb_325_KD_BCAP31_SRP320890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31893
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
ABCA1_OE_GDS2303_189_mouse_LDL receptor-deficient livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAL27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5049
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93104
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82717
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8034
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33403
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55276
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40175
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00694
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12451
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02294
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
BRD-K81220870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11664
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3204
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76834
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Oral sucker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832851
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166405
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924606
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34473
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949405
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926202
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06264
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.536
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870648
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61706
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904275
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947641
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07337
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10541450-41419_2023_6165_MOESM3_ESM.xlsx-Normal-P53-STIC-Unnamed_3_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94092
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.930999
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	CCLE Cell Line Gene Expression Profiles	1.0	2.04751
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35983
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939571
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
DBH_KO_GSE33906_53_mouse_heart (E10.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05131
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28232
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.957626
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34106
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.968955
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8651
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02025
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988827
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.35211
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
BRD-K74896637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62679
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44869
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67718
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07237
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21668
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07351
Cytoplasmic microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
infertility	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893336
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.951
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26647
SRSF7_02_133	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.85798
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.86701
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5995
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K17660756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21698
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53176
SBC-1	GDSC Cell Line Gene Expression Profiles	1.0	1.90951
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54478142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01724
BRD-K10923439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93789
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
ciliary cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.6848
parameters	GeneRIF Biological Term Annotations	1.0	null
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.03296
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNGM	CCLE Cell Line Gene Expression Profiles	1.0	1.80673
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45433
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44482
A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83144
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954201
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11219023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02772
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.563
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2692
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6867
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34982
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855526
organelle	GO Cellular Component Annotations 2015	1.0	null
Optic disk drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K51858914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6359
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RAD21	ENCODE Transcription Factor Targets	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50444
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35731
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26807
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.271533
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
anchoring junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17243
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830036
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.95541
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32018
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01708
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048953
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051918
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70642
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.572128
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.363
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.978877
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02248
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59701
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66804
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77105
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26356
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052532
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00988
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54606
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM19	DepMap CRISPR Gene Dependency	1.0	2.63944
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	3.4884
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.03641
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826229
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77605
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19005
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14155
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896026
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05124
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19055
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91339
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67163
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97284
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881297
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929153
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0227
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5127
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10673
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06769
CPSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.853477
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1502
BRD-K79627231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15896
Congenital contractural arachnodactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.96269
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16876
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33301
Perturb_17674_OE_PGRB_SRP252069	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87527
GTEX-SNOS-1726-SM-32PLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.6461
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Pharyngeal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61032
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64086
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64137
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.470406
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02529
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922213
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27914
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98873
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04819
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18138
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.244962
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891353
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K37203945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10062
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35736
BRD-K29060081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01064
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3869
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842549
sperm motility	GO Biological Process Annotations 2015	1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner dynein arm assembly	GO Biological Process Annotations 2015	1.0	null
abnormal mucociliary clearance	MGI Mouse Phenotype Associations 2023	1.0	null
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
Brachydactyly type C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966772
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
sperm	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32264
Microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0579
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.3394
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36365
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38714
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47084
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00243
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMSB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94139
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97411
BRD-K82048228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05927
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18744
CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08865
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.087
MERO41	DepMap CRISPR Gene Dependency	1.0	2.53438
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47766
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K86630280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16089
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.346
BRD-K74632893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69159
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	1.65907
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Radial spoke stalk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17628
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.47905
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40447
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15416
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04775
IL9	MSigDB Cancer Gene Co-expression Modules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5159-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01503
PECAPJ49	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46291
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89315
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal male germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.29085
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969393
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.337
cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.158835
Perturb_15705_KO_Rnf20_SRP304263	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.36967
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44876
HL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88946
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11095
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36269
cellular macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
Phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.67
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16271
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41316
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74397
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4011
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02125
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7857
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BRD-K63663384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78052
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	3.16798
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56273
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98133
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03564
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
cell-substrate junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
S117	DepMap CRISPR Gene Dependency	1.0	2.47481
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.22505
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Perturb_6588_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.6532
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81667
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
BRD-K71221636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16964
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73321
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
BRD-K41324679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01739
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02369
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03601
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15131
BRD-K54861624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05101
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nizatidin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56438
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69136
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0153
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947641
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20788
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterus-ciliated epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.806814
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3686
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916626
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43404
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76072
BRD-K89062214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73289
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4347
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69735
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23412
abnormal trachea morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.162763
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12149
abnormal sperm axoneme morphology	MPO Gene-Phenotype Associations	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75595810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0104
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1514
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84574
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19554
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834394
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14613
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70558234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01696
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17628
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23006
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70661
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844371
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11804
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
Male infertility due to acephalic spermatozoa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.513
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.214
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3959
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87709
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27793
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12046
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77551
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22495
Spermatogenic failure 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.775
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11472
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
OS252	DepMap CRISPR Gene Dependency	1.0	2.68192
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2037
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16196
BRD-K31479060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34317
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829279
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9295
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34069
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99953
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34421
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14315
BRD-K44052748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25847
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9736
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12392
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.548513
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04158
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74953
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51812
Perturb_9482_KO_Stat5_SRP144233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.91299
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65483
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841656
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3263
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.496
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564035
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24748087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08528
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53356
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47773
abnormal respiratory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2181
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167915
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44164
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28783
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bronchiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61813
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885904
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5623
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39897
GSE142684_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Focal adhesion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11931
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05621
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	2.40698
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92639644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10784
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37224
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27402
BRD-K40776502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51139
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	0.991446
CORL47	DepMap CRISPR Gene Dependency	1.0	2.84684
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50119
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18516
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.507977
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gill raker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.047
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12163
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6463
Sensory dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17143
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45587
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.2
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56519
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887826
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.41447
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53773
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09226
STAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31086
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
HEC251	CCLE Cell Line Gene Expression Profiles	1.0	1.47537
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5192
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29648
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.29085
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.57252
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55276
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71861
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05987
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982271
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74478
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40946
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24288
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.10753
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.327581
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K36347292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49984
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25502
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49703
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09757
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80739863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05257
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59115
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.00124
4842_MAPRE3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.517314
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45928
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85975
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38516
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44932450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26051
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1605
Perturb_16482_KO_Irf6_SRP173804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82022
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.76528
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9404
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
Sperm connecting piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27495
BRD-K78009480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.46801
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941081
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43786
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49097
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
BRD-K92613860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1908
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
nes	HPA Cell Line Gene Expression Profiles	1.0	1.31525
PCI38	DepMap CRISPR Gene Dependency	1.0	2.46099
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20986
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4217
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13381
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51482
Protein phosphatase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
HT1080	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6839
medrysone-2544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81605
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78465
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23395
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09628
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6387
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.93448
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82003
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
JJN3	DepMap CRISPR Gene Dependency	1.0	2.21186
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K09078201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70757
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20549
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	1.3795
GFI1B	ChEA Transcription Factor Targets	1.0	null
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46728
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.592
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35693
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.17511
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3866
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12699_KO_Ezh2_SRP222765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.40791
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979989
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18621
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9177
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36014
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72964
leflunomide-5884	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell projection	GO Cellular Component Annotations 2015	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1873
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10379
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70976
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76266
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968508
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88108
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2903
BL1021 (FAM184B)	NURSA Protein Complexes	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
murine	GeneRIF Biological Term Annotations	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
KNS81	DepMap CRISPR Gene Dependency	1.0	2.77855
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97866
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621449
BRD-K51298794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35228
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874217
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07109
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44319
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50898
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65074
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37111
BRD-K02788568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39393
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33971
BRD-K28997108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20623
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16507
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45639
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
hsa-miR-4290	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20696
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37464
PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4f-NOL9_KD_downreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.23335
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992214
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.27453
pathology	GeneRIF Biological Term Annotations	1.0	null
cell projection organization	GO Biological Process Annotations 2015	1.0	null
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90059
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82005
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.00865
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890644
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88786
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
motility	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24676
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
4955_MED4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.563193
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14775
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.09442
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77023196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52534
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45445
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K62979806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37236
BRD-K67096634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06053
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902841
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40774
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.84315
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_AAM-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91183
shikonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27366
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19425
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947641
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
measurements	GeneRIF Biological Term Annotations	1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49996
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85829
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91481
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24948
H3K36me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897097
flumethasone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14907
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22583
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.106
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0789
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14904
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.535
KP-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45771
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44323
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99308
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04739
BRD-K02403042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43749
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74489
ATXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15631
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63027
BRD-K84846130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15732
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40629
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27703
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61464
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883071
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.845083
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST-SL2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55558
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881757
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00985
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	2.0449
Perturb_13151_KO_Atxn7l3_SRP269420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.90304
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51232
DV90	CCLE Cell Line Gene Expression Profiles	1.0	2.74985
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18779
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BIN67	DepMap CRISPR Gene Dependency	1.0	2.38359
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57568
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02898
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334865
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05447
Perturb_13457_OE_Smn1_SRP366489	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.50513
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872868
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58197
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.076
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5781
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47275
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15073
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	2.93266
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45337
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986683
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44699
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1159
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.136745
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989855
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.701
Mitotic spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01496
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15393
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36395
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847033
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.496
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11547
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15291_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.80887
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20245846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36517
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32844
BRD-K17339982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36261
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.936
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42289
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.2533
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.60841
BRD-K35429561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42943
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911127
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54462
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3959
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40878
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82259
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4906
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631527
BRD-K47690679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27124
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09371
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.563
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40402
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05012
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524966
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74393
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.13781
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17526
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59735
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03564
MWP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02654
BICR16	DepMap CRISPR Gene Dependency	1.0	2.64884
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76896
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41812
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.934
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944712
BRD-K89476673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26808
BRD-K18332967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15643
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992948
PMC2665242-gkp077_nar-02582-s-2008-File009.xls-Supple_Table3_CTCF-Unnamed_4_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15622
10795_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.566678
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01658
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30726
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932487
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8837
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1498
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
NCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93274
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907819
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86489
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63869
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07638
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4448
NFYA_01_355	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64144
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78805
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837421
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66112
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
cilium organization	GO Biological Process Annotations 2025	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_upregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K73635724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92704
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17222
ZDHHC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29469
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41457
REST	ENCODE Transcription Factor Targets	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74415
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14636
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07882
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3332
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59778
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71944
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09078
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10733
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969263
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2066
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960339
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2796
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54366
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963202
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
BRD-K76960042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63784
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21296
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49496
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85944
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40146
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54042
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.29085
Perturb_13713_KO_ASXL2_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.98284
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
SNU46	DepMap CRISPR Gene Dependency	1.0	2.62154
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26761
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30557
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.45612
linked	GeneRIF Biological Term Annotations	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.21672
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.916115
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0528
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10498
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
protein complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18765
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897262
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836603
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05348
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
BRD-K35407043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14563
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13356
TP53	ChEA Transcription Factor Targets	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934617
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.47427
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
ciliary part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K96945047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61248
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.405
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40912
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30033
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56537
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931629
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76204
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168847
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886969
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80997
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.997
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30177
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81082
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	2.13902
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-HOXD4-Unnamed_7_HOXD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.293637
ZXDB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51905
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06189
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50448
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446807
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048953
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2878
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.111
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71764
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37844
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11705
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46336
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8314
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.535
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43815
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20300634-T2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58958
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871462
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.216
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.96405
BRD-K10048365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01995
protein complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33537
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41245
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.09608
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67255
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73775
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47588
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.68716
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.632669
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07729
nucleus	GO Cellular Component Annotations 2023	1.0	null
BRD-K63887881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04455
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09163
Vitellarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86706
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.742
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
suxibuzone-2503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878223
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40562
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28102
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9732
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.799276
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	3.02712
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.469
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31643
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879053
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10475
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24725
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13941
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34804
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841322
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hereditary neuropathy with liability to pressure palsies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19879
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25776
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17628
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38785
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059498
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12412
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17674
G402	DepMap CRISPR Gene Dependency	1.0	2.99558
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8805
abnormal cilium physiology	MPO Gene-Phenotype Associations	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.89078
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17873
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71816
hairpin sperm flagellum	MPO Gene-Phenotype Associations	1.0	null
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44816
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90416
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870518
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92409
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.369747
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.65063
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55471
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6946
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24097
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
TIA1_KO_GSE54418_266_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1268
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50858
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292436
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13476
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46439376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30653
Mastigoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04635
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
ECC12	GDSC Cell Line Gene Expression Profiles	1.0	2.39177
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91449
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32097
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855526
BRD-K96322674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00269
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Perturb_12701_KO_Anxa5_SRP379319	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52527
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17628
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79279
BRD-K71612465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29649
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
available	GeneRIF Biological Term Annotations	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844659
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sperm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080992
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormal sperm flagellum morphology	MPO Gene-Phenotype Associations	1.0	null
betamethasone-6728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.012
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	1.23069
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87164
BRD-K28953184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43873
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57375
mRNA_YY1_22210892	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1187	DepMap CRISPR Gene Dependency	1.0	3.23638
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179985
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.576
axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45478
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
BRD-K05357297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56175
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.719932
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830036
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.904791
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18102
Ovarian cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939797
HCC2429	DepMap CRISPR Gene Dependency	1.0	2.33501
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.546
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518465
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
capsaicin-3034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07247
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-NR4A2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28133
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.425726
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66173
Anchoring junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
BRD-K92460921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55913
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24698
NCI-H720	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09981
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
BRD-K61050695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7254
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93847
Acute Myeloid Leukemia_LAML_TCGA-AB-2991-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914163
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11123
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827321
BRD-K36228696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3357
NCO2	CCLE Cell Line Gene Expression Profiles	1.0	1.68319
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87008
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.1254
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68828
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29852
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.136
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.94318
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0545
Ovotestis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84945
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42208
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95184
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872512
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94546
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18535
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1226
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07575
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71861
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
BRD-K48914099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67691
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32656
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49059
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71452126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33426
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59417
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11086
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K16436767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64215
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle assembly	GO Biological Process Annotations 2025	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863268
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
ATM_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.109
VCAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82125
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2272
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K21579116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21301
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949981
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855129
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58687
127399	DepMap CRISPR Gene Dependency	1.0	2.61441
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.6
10803_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540932
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6183
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80124
PMC2665242-gkp077_nar-02582-s-2008-File009.xls-Supple_Table3_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72991
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02681
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93448
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910224
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77976
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21067
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21008
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63805
BRD-K02987495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11157
axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.51694
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39635
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.939451
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2411
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.06036
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5695
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943423
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.51164
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09255
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899134
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0421
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.73559
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17928
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01621
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10763
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.195
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3961
BRD-K29309835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4413
nucleus	GO Cellular Component Annotations 2015	1.0	null
BRD-K34382498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06728
BRD-K43284834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15021
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.08868
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tektin	GeneRIF Biological Term Annotations	1.0	null
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44451
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.10264
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71893
SNU626	DepMap CRISPR Gene Dependency	1.0	3.10467
BRD-K91361836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2999
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85153
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_24_AAM-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16298
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56816
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16999
SKMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13368
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73587
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06658
BRD-K59913416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91979
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897018
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
PMC11055867-41598_2024_60205_MOESM1_ESM.pdf-18-ESRRG_ESRRG	Rummagene Transcription Factor Associations 2026	1.0	null
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4824
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02089
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
RDES	CCLE Cell Line Gene Expression Profiles	1.0	1.89587
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
BRD-K06148713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02784
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05487
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16822
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
BRD-K08629159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02944
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6175_OE_Zeb1_SRP187711	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.86459
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990811
Perturb_13167_KO_Trp53_ERP108431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.67411
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57535
TYKNU	CCLE Cell Line Gene CNV Profiles	1.0	1.50088
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978967
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32438
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64863
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71861
SALL4	ChEA Transcription Factor Targets	1.0	null
Flemming body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12377
BRD-K53814023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12233
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53046
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68842
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15387
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
GSE187005_3_v_4_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.91405
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.511
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7727
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14051
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23766
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07783
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11384
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917255
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.072
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25566
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79498