association	dataset	threshold value	standardized value
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7079
nuclear inner membrane	GO Cellular Component Annotations 2025	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3881
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3866
Gordon Holmes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Ureterolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.237
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3714
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21218
Nuclear envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47804
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.02
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
Photophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.351
FAM53B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98029
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33787
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.6479
GSE199606_6_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9686
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.633
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4564
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.112
Mitochondrial cloud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.969
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60649
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.36
homologous chromosome segregation	GO Biological Process Annotations 2025	1.0	null
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.1682
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8943
Chromosomal region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.92
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1852
meiotic telomere clustering	GO Biological Process Annotations 2025	1.0	null
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0051
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Galloway-Mowat syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
Nuclear lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4068
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.039
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.75
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.959
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.633
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.16074
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6921
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.284
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE61117_0_v_1_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.255
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNA polymerase V complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.201
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3158
nuclear membrane	GO Cellular Component Annotations 2025	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.958
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.366
Nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.284
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.854
HslUV protease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.1233
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
Centrosome	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27267
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7504
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.982
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.174
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.10352
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1814
Spermatogenic failure 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.105
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6138
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0798
Nuclear matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0077
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.744
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Nurse cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.723
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.608
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57176
INSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39571
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52184
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8106
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
TSSK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03578
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_6_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2024
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2215
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
Mitotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.162
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2026
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7095
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MutSgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0121
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8634
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17401
Alpha thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
Germarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.179
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.893
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7607
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9051
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fs6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
chromosome, telomeric region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61813
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1571
Nuclear membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
llcmk2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
PMC12420540-44154_2025_254_MOESM1_ESM.xlsx-supplementary_S7-FST_PI_XPCLR_TGB_VS_ZSG_gene_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0527
Nuclear inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.056
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Nuclear envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.084
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5694
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
Dyskeratosis congenita	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9414
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.562
Nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.633
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.513
Male infertility due to acephalic spermatozoa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.335
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6506
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
Revesz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ovariole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9138
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3413
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7877
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fusome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.3213
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Alpha DNA polymerase:primase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.444
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47818
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4589
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0657
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9225
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0455
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4208
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.377
Monopolin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7771
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59669
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2051
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
LIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97447
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3916
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6403
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3014
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9156
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.89046
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2173
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00016
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3919
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4519
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.633
496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.11035
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
GSE189683_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65296
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1443
GSE199606_6_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE139455_4_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.5137
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Nuclear membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.99
Microtubule organizing center	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.183
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.077
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.885
GDPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.66328
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85855
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
Spermatogenic failure 59	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.845
Hemochromatosis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.4569
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0631
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9362
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5102
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
GSE130081,GSE130082_4_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.8407
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2525
GSE146687_2_v_3_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76622
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.091
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
PMC8298514-41467_2021_24813_MOESM22_ESM.xlsx-RELA_H3K27ac-SYMBOL_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.422
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1267
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9006
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4862
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
chromosome, telomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.367
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4339
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mitotic spindle assembly checkpoint MAD1-MAD2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6931
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.0073
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.601
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.89518
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.765
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00275
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.9644
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.01596
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2129
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5086
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2521
Bloom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Early recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8258
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0584
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.9063
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9737
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.5
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.78332
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4146
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9948
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23993
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.986
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.28
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7802
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.36
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.204
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9371
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.043
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8637
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6111
chromosome localization to nuclear envelope involved in homologous chromosome segregation	GO Biological Process Annotations 2025	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_17_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9369
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.89454
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9768
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3567
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20393
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5947
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81368
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8431
Spermatogenic failure 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7913
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5398
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
Nuclear envelope lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5916
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.412
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.633
RIMS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30722
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9044
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82255
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2025	1.0	null
496100292_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52265
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4065
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
GSE198165,GSE198166_7_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1467
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2309
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
telomere localization	GO Biological Process Annotations 2025	1.0	null
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20979
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9463
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Telomerase holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.104
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2772
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
46,XX sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3626
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61877
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.415
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5139
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85033
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
ERCC4-ERCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
Hereditary spastic paraplegia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6236
PMC12549544-mmc2.xlsx-AA_D28_VS_D42-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55007
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9716
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1111
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.2239
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.8895
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4253
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.915
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6857
Nuclear membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.257
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.5992