association dataset threshold value standardized value SPI1 ENCODE Transcription Factor Targets 1.0 null 496100332_HIP_possible Alzheimer's disease_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.62731 CLSPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041 Brain Lower Grade Glioma_LGG_TCGA-QH-A6XA-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE231891_1_v_0_cdk8_human RummaGEO Gene Perturbation Signatures -1.0 null Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.6891 TE159T CCLE Cell Line Gene Expression Profiles 1.0 1.54117 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2327 ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0369 superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33999 PNPO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94019 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0165 SS18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.26742 GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null CDK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79561 Pseudoxanthoma elasticum DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.058 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48022 KYSE520 CCLE Cell Line Gene Expression Profiles 1.0 1.36245 LCLC97TM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.51521 r2 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0409 HCC1419 DepMap CRISPR Gene Dependency 1.0 4.15414 Nucleus of the lateral lemniscus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01504 pituitary GTEx Tissue Gene Expression Profiles -1.0 -1.17428 hsa-miR-4307 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.1102 MRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63443 MRPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77974 CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Saethre-Chotzen syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.157 CTNNB1-20460455-HCT116-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4222 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.9897 DBTRG05MG DepMap CRISPR Gene Dependency 1.0 3.40704 SETBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15779 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Non-alcoholic fatty liver disease histology (other) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14118 CHD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69641 Synaptonemal structure COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.041 496100648_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.09171 RDM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59999 hsa-miR-4760-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.313 ZBTB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48334 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1277 AKAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82477 intermediate stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23892 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3158 ALKBH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34428 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null ZMPSTE24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0245 r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36553 Lung adenocarcinoma_LUAD_TCGA-05-4434-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null INSIG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95879 Non-alcoholic fatty liver disease histology (other) GWAS Catalog SNP-Phenotype Associations 1.0 0.057619 GSE206729_4_v_0_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94585 ZBTB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14742 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0605 EHF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92793 intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20317 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66498 PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27793 VAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41042 H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11957_KO_Cnot4_SRP285155 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.28375 RAB12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38822 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59047 DPY19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70863 UOK101 CCLE Cell Line Gene CNV Profiles 1.0 1.43696 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP Rummagene Transcription Factor Associations 2026 1.0 null GSE195568_1_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12016 ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887106 Meiotic spindle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8951 MYCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46674 GSE206270_1_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8F_Het1A-GATA6_2d_5x_closed-Gene_Name_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null NCIH524 CCLE Cell Line Gene CNV Profiles -1.0 -1.73068 RFX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94713 C1RL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5375 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2963 Cholesterol dbGAP Gene-Trait Associations 1.0 0.213671 GTF2IRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19887 Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05541 PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6A-targets_down-EWSR1_FLI1-KDM6A_downregulated_targets_upon_KDM6A_knockout_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42059 brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 PIAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54088 ZNF93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7929 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54979 layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21901 PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Spermatogenic failure 23 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.412 PABPC4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29408 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18686 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.367 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05158 Frontal pole, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87833 magnocellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01917 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZKSCAN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19318 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.367 RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHU011 DepMap CRISPR Gene Dependency 1.0 3.49682 ETS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86489 GSE221327_10_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null SEZ6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19089 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21225 RNASE8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52407 DEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73116 anterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17908 MCAS CCLE Cell Line Gene CNV Profiles 1.0 1.69007 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17268_KO_Sox30_SRP139811 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE166914_1_v_2_abemaciclib_human RummaGEO Drug Perturbation Signatures -1.0 null Field CA2, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.064 BC3C CCLE Cell Line Gene Expression Profiles 1.0 1.71206 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0378 H3K27me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NR0B1 ChEA Transcription Factor Targets 1.0 null hsa-miR-383 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null KNS42 DepMap CRISPR Gene Dependency 1.0 3.15746 DPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86726 PPP2R5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32861 MAX ENCODE Transcription Factor Targets 1.0 null r1 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19586 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.0839 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.3063 CCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16061 SNU1105 DepMap CRISPR Gene Dependency 1.0 2.04533 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46018 LOXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43 ChIP_TCF3_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7659 Geniculate group, ventral thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0237 RIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64541 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892811 ATP5MC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88087 496100335_PCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.4689 IFT80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53331 TGFBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66591 Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03287 GR MotifMap Predicted Transcription Factor Targets 1.0 null PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null MRPL47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 NCIH23 CCLE Cell Line Gene Expression Profiles -1.0 -1.8983 medial basal reticular formation of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53077 m2 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33055 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.53521 496100475_TCx_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56455 ANKRD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45092 COLO775 CCLE Cell Line Gene Expression Profiles -1.0 -1.47153 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5434 LU-99A COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 TMCO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18341 NCIH2347 CCLE Cell Line Gene Expression Profiles -1.0 -1.75351 C99 DepMap CRISPR Gene Dependency 1.0 4.40139 Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.446 CCT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91454 SMYD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30658 Subiculum, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11888 ChIP_TCF3_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.257311 GSE139016_0_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14223 HOPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89516 Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0072 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null MRI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57565 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31157 CNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53423 medial part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04294 HLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21211 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06757 mantle zone of m2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56888 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2327 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53965 mantle zone of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26954 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22808 SHPRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01081 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59519 FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null IL27RA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54101 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.853771 NIHOVCAR3 DepMap CRISPR Gene Dependency 1.0 5.95989 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14543 Primary somatosensory area, nose, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48363 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1477 IGF1R_knockdown_52_GSE16684 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.63689 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r8 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12692 Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null HDLBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08907 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3874 Primary somatosensory area, barrel field, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11888 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04361 Sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.247 Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.77412 PDE6D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85547 ESR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68699 GATA1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null KMH2 CCLE Cell Line Gene CNV Profiles 1.0 2.12265 AR ChEA Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5933-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VMRCLCP CCLE Cell Line Gene Expression Profiles 1.0 1.69227 gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q8-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8876 UQCRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78244 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17536 DNAJB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4087 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49315 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFDN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 6.27682 intermediate stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08844 CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormality of reproductive system physiology GWASdb SNP-Phenotype Associations 1.0 0.331012 UNC5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83447 mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33999 Mel-18_KD_GDS2724_103_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20147 r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49315 r7 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00805 GTPBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21053 LUC7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92546 hsa-miR-4643 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Spermatogenic failure 25 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.354 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77553 PRMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12756 C19orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22936 42MGBA CCLE Cell Line Gene Expression Profiles 1.0 1.86644 intermediate stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05051 MOLP8 CCLE Cell Line Gene CNV Profiles -1.0 -1.82344 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892811 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.9089 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RTKN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15073 hepatobiliary disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 DCTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77771 Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01416 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RGL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74888 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7967 hsa-miR-466 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 CUL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72991 Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06699 496100449_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.39397 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NKX3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58826 HTT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03549 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.891642 THP1 CCLE Cell Line Gene CNV Profiles -1.0 -2.27537 ACSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.096 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null STARD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61864 A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.04846 496100323_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33511 PIK3R4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99065 Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP1CC Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vascular disease GWASdb SNP-Disease Associations 1.0 0.078755 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -1.52296 caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44235 NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -1.53149 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62743 kidney GTEx Tissue Gene Expression Profiles -1.0 -1.17428 H3K27me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1918 intermediate stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54596 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57113 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01818 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05884 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.55859 Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5471 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66596 Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1603 Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOMEZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11931 layer 6 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21901 TBC1D10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66846 SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74631 lateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47796 Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB7 DepMap CRISPR Gene Dependency 1.0 2.30917 AURKAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83564 METTL21C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65522 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.02749 Cleidocranial dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.003 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9533 NCOA2_KO_GDS5087_24_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CCND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87272 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YO-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248858_5_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.44184 NRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01107 TTC709 DepMap CRISPR Gene Dependency 1.0 2.88217 retropontine reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30251 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22885 TCEAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71737 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1792 CCLE Cell Line Gene Expression Profiles 1.0 1.53652 STEEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31272 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Pachytene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.989 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28719 HCC366 CCLE Cell Line Gene Expression Profiles 1.0 1.37472 intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34169 intermediate stratum of SePal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32486 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18686 RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.5703 PSMG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60783 Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.868 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.5317 Lung squamous cell carcinoma_LUSC_TCGA-18-3411-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68426 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.964231 hsa-miR-513b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 POU2AF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09754 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38306 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40797 ZNF852 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84741 LU99 CCLE Cell Line Gene Expression Profiles -1.0 -1.52391 DNLZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94159 ORAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58996 accessory entopeduncular nucleus (post-migratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22084 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR0B1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Linear nucleus of the medulla Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26882 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03409 BAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95795 SKMEL30 DepMap CRISPR Gene Dependency 1.0 3.07981 PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.34134 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WQ-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.019 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.429 Age at first sexual intercourse GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.969897 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU398 CCLE Cell Line Gene CNV Profiles 1.0 1.58346 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null sc1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.26 ChIP_NANOG_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE202434,GSE202438_10_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF532 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68862 SDR39U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52272 superficial stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24728 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81845 C1orf21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66507 SOX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46864 KIF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91861 SMARCA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01711 GSE202434,GSE202438_10_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null PDXDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5207 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null m2 part of nucleus parabrachialis pigmentosus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29333 NFKBIE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50366 Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94762 496100284_FWM_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.4432 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04611 Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.054 Pfeiffer syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.212 CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3294 RARA_KD_GDS4065_42_human_MCF-7 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ANKRD13D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33042 superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1705 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPAG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46281 ANP32D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11712 COTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49699 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantia innominata/basal nucleus, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05677 EZH2 ENCODE Transcription Factor Targets 1.0 null FGFR3_KD_GDS4454_78_human_RT112 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05957 GSE175787_11_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2555 Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null D502MG DepMap CRISPR Gene Dependency 1.0 2.72896 Arteries dbGAP Gene-Trait Associations 1.0 0.060258 intermediate stratum of m2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8408 r6 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29222 hsa-miR-192 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Synaptonemal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.048 nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11567 496100561_PCx_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01999 496100540_TCx_probable Alzheimer's disease_TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.34529 GSE175787_11_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09174 MSH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49656 L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47286 PUSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40921 superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88872 TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30294 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4973 Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38584 EBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43944 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NL-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE221327_1_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null SW948 CCLE Cell Line Gene CNV Profiles -1.0 -1.7268 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73495 cervix uteri GTEx Tissue Gene Expression Profiles 1.0 1.52357 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10162 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4075 SNU407 CCLE Cell Line Gene CNV Profiles -1.0 -1.62133 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39796 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARHGEF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21672 ChIP_MYC_19079543 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08013 Intercellular bridge COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.819 GSE235550_2_v_0_hspa9_human RummaGEO Gene Perturbation Signatures 1.0 null Cerebrospinal fluid AB1-42 levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 APBA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73436 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R4-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WSB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42476 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32743 Koelliker-Fuse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81448 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06297 Entorhinal area, medial part, dorsal zone, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29576 hsa-miR-570 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Primary somatosensory area, unassigned, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63748 VPS9D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75877 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5754 SPATC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44618 superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57167 Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.922657 ENOSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64729 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.6212 GSE248858_6_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZNF618 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.264 male reproductive system disease GWASdb SNP-Disease Associations 1.0 0.370971 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18686 ARL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76725 Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210990,GSE211030_3_v_1_kmt2d_mouse RummaGEO Gene Perturbation Signatures -1.0 null internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59325 Subiculum, dorsal part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47881 496100547_HIP_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18208 male infertility GWASdb SNP-Disease Associations 1.0 0.669951 ventrolateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30476 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04282 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.964231 PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.4 SP110 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37212 SNU16 DepMap CRISPR Gene Dependency 1.0 2.15783 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.128398 OSBPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33498 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null GLIS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62894 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38246 GSE239844_4_v_2_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6052 Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.879518 CEP41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.75812 PIGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71601 Leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.376 RIOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49196 hsa-miR-4457 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 TRIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01051 HDHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64611 SMAD4 ChEA Transcription Factor Targets 1.0 null intergeniculate leaflet Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33055 Lateral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08489 decreased fertility GWASdb SNP-Phenotype Associations 1.0 0.574011 GSE149264,GSE149267_4_v_3_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null EM2 DepMap CRISPR Gene Dependency 1.0 3.11821 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04361 disease GWASdb SNP-Disease Associations 1.0 0.027782 Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NIPSNAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22408 Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.68937 KPNRTBM1 CCLE Cell Line Gene Expression Profiles -1.0 -2.40348 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15182 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887106 Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892811 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248858_4_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null liminal alar domain of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30476 ISCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36115 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94585 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06554 superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49078 496100431_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.73394 hsa-miR-651 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 RASL11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86942 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KELLY CCLE Cell Line Gene Expression Profiles -1.0 -1.49847 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.3606 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3942 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09372 Crouzon syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.145 Ebf2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4209 Cerebral arterial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 mRNA_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7017 Ventral part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04244 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.80191 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.4523 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.486 KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.36382 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCT15 DepMap CRISPR Gene Dependency 1.0 3.79518 HSCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18912 superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28609 EP300 ENCODE Transcription Factor Targets 1.0 null SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9828 IQSEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63768 Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA1, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03567 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.212 CCZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74446 Parabrachial nucleus, lateral division, external lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93667 PC14 CCLE Cell Line Gene Expression Profiles 1.0 1.78207 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1397 Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.008 TET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31397 KDM5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88617 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SS-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCT116 DepMap CRISPR Gene Dependency 1.0 4.87743 TMEM18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17187 TEX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40798 FGF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17104 GPSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47739 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.126 KDM4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51274 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3358 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93003 RAB32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53096 KASUMI1 CCLE Cell Line Gene CNV Profiles 1.0 1.41226 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2428 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cholesterol GAD Gene-Disease Associations 1.0 null Field CA2, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.091 SKNMC CCLE Cell Line Gene CNV Profiles -1.0 -1.53013 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null DIS3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22303 GSE256181_1_v_0_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null FN3KRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43573 PNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8152 fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34207 PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78002 SMARCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14499 uterus GTEx Tissue Gene Expression Profiles 1.0 1.26025 TO175T CCLE Cell Line Gene Expression Profiles 1.0 1.46274 ACHN CCLE Cell Line Gene Expression Profiles -1.0 -1.50407 Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28463 ELK1 JASPAR Predicted Transcription Factor Targets 1.0 null NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.37366 FAM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29615 NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -1.78737 hsa-miR-4502 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78144 CNMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02791 MCM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05066 FIGNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36137 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03409 CMAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97774 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null ANAPC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78599 Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-654-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -1.6126 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937439 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF Rummagene Transcription Factor Associations 2026 1.0 null ARL8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3537 AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53709 CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66041 ELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15238 TEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18246 HCC1937 CCLE Cell Line Gene CNV Profiles 1.0 1.52859 Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10581 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.70509 intermediate stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31111 OCUG1 DepMap CRISPR Gene Dependency 1.0 2.02219 BHLHE40 ENCODE Transcription Factor Targets 1.0 null vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16345 NACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7458 CTCF ENCODE Transcription Factor Targets 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8705 reticular formation of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.212 SUPT3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92286 NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54426 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28413 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6695 COGN305 DepMap CRISPR Gene Dependency 1.0 4.31638 HEC50B CCLE Cell Line Gene CNV Profiles -1.0 -1.8965 TEX41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95245 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 1.01655 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.212 Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.41824 PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA Rummagene Transcription Factor Associations 2026 1.0 null r5 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3088 Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0692 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.84515 Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.872196 superficial stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05677 TCF3 ChEA Transcription Factor Targets 1.0 null CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PRR35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4966 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null POLR2AphosphoS5_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39742 DENND4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57904 SEMA4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23244 ChIP_NR0B1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null intermediate stratum of 5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82613 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 MYL12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17776 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TASOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44223 SCMH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12993 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REEP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39916 ERH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11025 male infertility GWASdb SNP-Phenotype Associations 1.0 0.574011 496100321_HIP_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10863 Spinal nucleus of the trigeminal, oral part, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05825 H4 CCLE Cell Line Gene Expression Profiles 1.0 1.68881 SIGLEC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65879 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3411 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66798 NRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94459 A673 CCLE Cell Line Gene Expression Profiles 1.0 2.31026 abnormality of the genital system GWASdb SNP-Phenotype Associations 1.0 0.095165 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2024 TNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07636 MYL12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64777 intermediate (interpositus) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41351 medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0609 NCOA2_KO_GSE41558_19_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55257 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6832 ACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32837 RCOR1 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles 1.0 1.33783 TE125T CCLE Cell Line Gene Expression Profiles 1.0 1.894 periventricular stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14223 SNU478 CCLE Cell Line Gene CNV Profiles 1.0 2.00343 ALG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64845 SRC-2_Deficiency_GDS5087_270_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-10q22_1_TP63 Rummagene Transcription Factor Associations 2026 1.0 null Beare-Stevenson cutis gyrata syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.805 GMPPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74294 Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56968 IFNAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30471 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7233-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06256 DKMG CCLE Cell Line Gene CNV Profiles -1.0 -1.61117 TMEM167A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56988 ASCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05557 NCIH1436 CCLE Cell Line Gene CNV Profiles 1.0 1.60816 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2408 H3118 DepMap CRISPR Gene Dependency 1.0 2.17772 r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0666 SRC-2_KO_GDS5087_485_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937439 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195568_3_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null H2AC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47255 CHD2 ENCODE Transcription Factor Targets 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98673 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17615 ELP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58008 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.993 HPAFII DepMap CRISPR Gene Dependency 1.0 7.50684 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC39A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34239 E2A_KO_GDS5084_401_mouse_DN2 thymocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MROH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87035 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2327 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1013 HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66612 THAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52218 Mesonephric duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.663 CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07204 NCIH1693 CCLE Cell Line Gene Expression Profiles 1.0 1.61697 INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93482 Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40699 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8517 SCMCRM2 DepMap CRISPR Gene Dependency 1.0 6.53266 RD DepMap CRISPR Gene Dependency 1.0 2.0736 BABAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23655 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intracranial arterial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 KIAA2013 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22077 ChIP_NACC1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22269 m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34277 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null CCDC77 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3101 Subparafascicular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42679 CCDC85B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0969 CBX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87273 subcuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08126 HOXA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24202 CL11 DepMap CRISPR Gene Dependency 1.0 2.43689 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.032996 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42781 Peripartum cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.035 MRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34314 ZNF34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5353 TMCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09184 rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32711 Frontal pole, cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24511 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11155 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TFEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5687 Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28476 GSE256181_1_v_3_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 AR-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null ZNF611 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27981 SCS214 DepMap CRISPR Gene Dependency 1.0 3.23517 496100467_FWM_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43898 liminal alar domain of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73544 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0465 ZNFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19589 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.567 MOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22298 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null T3M10 CCLE Cell Line Gene Expression Profiles 1.0 2.25128 GSE221327_6_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null CMPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10269 PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR Rummagene Transcription Factor Associations 2026 1.0 null LHX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84531 NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9066 Midbrain reticular nucleus, retrorubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01517 superficial stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01619 GATA1 ChEA Transcription Factor Targets 1.0 null ATG2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36048 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6273 APOBEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28111 GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null para-abducens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1449 TMPO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40155 KKU100 DepMap CRISPR Gene Dependency 1.0 4.14868 COA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0397 KIAA0232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90482 hsa-miR-4719 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05677 CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 GSE135514_8_v_3_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null ABCB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90157 FANCM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4225 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887911 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ChEA Transcription Factor Targets 1.0 null ZNF362 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46028 Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6474 Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60881 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -1.58761 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE248858_5_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90793 RNF207 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09188 HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12832 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870586 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null SUPT20H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74017 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.576437 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72283 Lateral posterior nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.091 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.7028 POU6F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18139 CUL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44457 OTULIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99736 Prostate adenocarcinoma_PRAD_TCGA-EJ-5508-01A-02R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE248858_6_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72283 NANOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10087 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90879 BHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27678 Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985588 TT2609C02 CCLE Cell Line Gene Expression Profiles 1.0 1.55017 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT549 CCLE Cell Line Gene Expression Profiles 1.0 1.39395 OVK18 CCLE Cell Line Gene CNV Profiles 1.0 1.52829 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.7813 METTL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.162 KANK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37854 RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE207433_2_v_3_crtc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NANOGNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45501 hsa-miR-4529-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 MN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97218 GSE239844_4_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4605 NR1I2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.61598 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MFN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29553 EIF5AL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60724 RWDD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45785 SNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27103 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.5037 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72513 E2A_KO_GSE43224_679_mouse_DN2 cells from WT and E2A-deficient murine fetal thymi GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01041 CD81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2023 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5532 Olfactory tubercle, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05262 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887911 PHETA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99854 TRIM52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00067 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76846 H4C6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.70545 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834134 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7781 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.913 MTSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98305 supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02873 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.056047 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIPK2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52041 MAFK ENCODE Transcription Factor Targets 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5801 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46917 Primary somatosensory area, barrel field, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.10705 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10462 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RNF144A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61713 hsa-miR-548c-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 SAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5956 FASLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10088 intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07386 NACC1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null JAG1_OE_GDS3571_40_human_endometrial stromal cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2703 MTLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58004 NCIH1666 DepMap CRISPR Gene Dependency 1.0 2.01019 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.627 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CM-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9492 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40485 BT20 CCLE Cell Line Gene CNV Profiles -1.0 -2.22609 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56618 TUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9587 RRP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21255 Accessory facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15303 NB17 DepMap CRISPR Gene Dependency 1.0 3.74464 GSE221327_4_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56888 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12236 Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZMYND19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99101 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.5926 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null AKTIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22066 hsa-miR-1265 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17536 GSE121866_1_v_3_six4_human RummaGEO Gene Perturbation Signatures 1.0 null PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3778 KCTD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70334 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null preisthmic tegmentum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33114 KLF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56818 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5568 CNOT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43729 SFXN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78337 retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08489 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.872504 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null reticular formation of basal m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.17795 Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.304 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24505 SLC2A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9788 496100400_PCx_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.91839 superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36766 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATXN2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86719 mantle zone of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04244 r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51507 ETS1 ENCODE Transcription Factor Targets 1.0 null ZNF133 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47282 KARPAS299 CCLE Cell Line Gene CNV Profiles -1.0 -1.40886 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937439 GSE182179_5_v_3_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-215 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR Rummagene Transcription Factor Associations 2026 1.0 null PHF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56336 Domain of unknown function with conserved HDNR motif InterPro Predicted Protein Domain Annotations 1.0 null Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.338 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.61715 H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-1287 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 FLT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74121 COQ4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76364 DECR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39099 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03632 ZNF783 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46874 dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.36399 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90752 TOV21G CCLE Cell Line Gene CNV Profiles 1.0 1.60728 HDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73941 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.86305 Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE218727_0_v_1_zkscan3_human RummaGEO Gene Perturbation Signatures -1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24079 Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81104 MOLM6 CCLE Cell Line Gene CNV Profiles 1.0 1.39052 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1302 PSORS1C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 ELK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8175 ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 NDRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8666 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5718 BT474 CCLE Cell Line Gene CNV Profiles -1.0 -2.54889 MCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19022 NCIH2004RT DepMap CRISPR Gene Dependency 1.0 3.17312 GSE239844_8_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 2.21798 GSE206270_2_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null PER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39762 artery disease GWASdb SNP-Disease Associations 1.0 0.109898 ZNF555 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56455 Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4XA-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07957 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC22A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0174 AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null GTF2E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58853 ZFAND2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88926 LU99 CCLE Cell Line Gene CNV Profiles 1.0 2.33815 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9195 Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 5.56691 GSE178714_1_v_4_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null ADM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18578 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61174 lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85195 Jackson-Weiss syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.555 CD248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90024 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548n TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837609 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5555-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2896 CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5493 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7311 SNU1079 DepMap CRISPR Gene Dependency 1.0 4.45027 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.6667 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MONOMAC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52585 Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9626 CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MCU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73707 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.185 tobacco use disorder GAD Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5ET-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548k TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 DU145 CCLE Cell Line Gene Expression Profiles 1.0 1.40773 sublayer 6a of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58125 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TEPSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89934 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.091518 SCLC21H CCLE Cell Line Gene Expression Profiles -1.0 -1.55891 MDAMB415 CCLE Cell Line Gene CNV Profiles 1.0 1.98978 TCF3-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3187-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28461 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20513 cell part LOCATE Predicted Protein Localization Annotations 1.0 null ZNF728 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44209 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 ES4 DepMap CRISPR Gene Dependency 1.0 6.62066 TCF3-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CTNNB1 ChEA Transcription Factor Targets 1.0 null PAX3 ChEA Transcription Factor Targets 1.0 null AKAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11739 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9846 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1861 INTS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33066 KYSE70 CCLE Cell Line Gene Expression Profiles 1.0 2.04755 PDLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14445 PROX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6782 r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57167 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17615 ENTREP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44102 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null isthmic part of the intermediate lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04272 KLF4 ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THRAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00074 PIPOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6798 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50365 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2839 PTDSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85252 MYC ChEA Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.882601 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1206 DHX32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31872 reproductive system disease GWASdb SNP-Disease Associations 1.0 0.156603 Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VWCE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84492 mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.940451 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5684-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10462 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.887106 BICR6 CCLE Cell Line Gene Expression Profiles -1.0 -1.52145 REST ChEA Transcription Factor Targets 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.13766 Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPL1 CCLE Cell Line Gene Expression Profiles -1.0 -1.74693 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.31746 PLBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6722 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9815 SLC4A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05895 ROS50 DepMap CRISPR Gene Dependency 1.0 2.21757 SKNSH DepMap CRISPR Gene Dependency 1.0 4.11912 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Schizophrenia DisGeNET Gene-Disease Associations 1.0 null GSE131649_4_v_11_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 NCI-H1781 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95468 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.308 MLX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5288 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55457 Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKRD61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09969 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09372 liver GTEx Tissue Gene Expression Profiles -1.0 -1.17428 intermediate stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20898 SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15462 A-CA-04-2009(H1N1)_30Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.58333 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles 1.0 1.80859 ASNSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66937 GSE202434,GSE202438_10_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0378 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6103 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CQ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSIP1_Deficiency_GDS2883_633_human_T-cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CENPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05935 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18686 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9318 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS934T CCLE Cell Line Gene Expression Profiles 1.0 1.4223 Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTPBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39327 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NCIN87 DepMap CRISPR Gene Dependency 1.0 2.62418 NCIH838 CCLE Cell Line Gene Expression Profiles 1.0 2.87292 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508 superficial stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19449 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.0616 reproductive system phenotype MGI Mouse Phenotype Associations 2023 1.0 null PMC9724253-12920_2022_1407_MOESM1_ESM.pdf-188-TET2_TET2 Rummagene Transcription Factor Associations 2026 1.0 null NCIH1651 CCLE Cell Line Gene CNV Profiles -1.0 -2.88808 NCIH358 CCLE Cell Line Gene Expression Profiles -1.0 -1.96989 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46637 VSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25278 LIN7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22085 BCKDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82006 all GWASdb SNP-Phenotype Associations 1.0 0.033408 IRF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22513 TEAD4 ChEA Transcription Factor Targets 1.0 null ZIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0904 superficial stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12364 GSE221327_5_v_0_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19857 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.964231 Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IALM CCLE Cell Line Gene Expression Profiles 1.0 1.4238 Pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.332 lateral part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26954 PDCD6IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34597 Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07738 Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 73.6066 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95994 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE121824,GSE121826_0_v_8_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null SNUPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90527 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 2.59987 RAB40AL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.38029 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49543 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.058758 GLUD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77879 BATF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94435 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.853984 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47047 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.867802 ZNF84 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46727 ventrolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73544 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.5771 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE280 DepMap CRISPR Gene Dependency 1.0 6.23409 TMK1 DepMap CRISPR Gene Dependency 1.0 2.85314 icSARS CoV_30Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.67023 arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.231169 PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83658 1321N1 CCLE Cell Line Gene Expression Profiles 1.0 1.53109 NCIH1435 CCLE Cell Line Gene CNV Profiles 1.0 1.83796 YD38 DepMap CRISPR Gene Dependency 1.0 2.04432 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.321 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.08328 Parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23338 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61006 GSE248858_4_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures 1.0 null NFIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09165 mantle zone of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28591 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.57836 FBLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5269 intermediate stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0052 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937439 SLC39A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89271 LENG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37492 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09943 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.292362 CREB1-23762244-HIPPOCAMPUS-RAT ChEA Transcription Factor Binding Site Profiles 1.0 null BPGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62144 Primary somatosensory area, unassigned, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02854 GSE135439_0_v_1_pax5_human RummaGEO Gene Perturbation Signatures 1.0 null SCN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42733 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMSB15A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01922 ChIP_DMAP1_20946988 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null KIF21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45203 dorsolateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1433 GSE112962,GSE112963_2_v_1_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null TE5 CCLE Cell Line Gene Expression Profiles 1.0 1.6665 digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.13417 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF773 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29087 ERCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44698 Prostate adenocarcinoma_PRAD_TCGA-EJ-5527-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE232631_4_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Field CA1, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03005 Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03425 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.292362 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86065 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79943 DNAJB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21288 TEX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19889 496100521_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38273 NCIH2228 CCLE Cell Line Gene Expression Profiles 1.0 2.20047 GSE166914_1_v_0_abemaciclib_human RummaGEO Drug Perturbation Signatures -1.0 null MAPK14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6292 DLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24545 Intracranial berry aneurysm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.592 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8221 medial parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23892 MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03693 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arteriovenous malformations of the brain DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.289 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -3.59596 H2AFZ ENCODE Transcription Factor Targets 1.0 null subpretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78575 JUND_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82375 HCT116 CCLE Cell Line Gene CNV Profiles 1.0 1.49012 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77553 KMS21BM CCLE Cell Line Gene CNV Profiles -1.0 -1.97827 RSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24679 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5555 SLC29A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38643 STYXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93348 MKN7 CCLE Cell Line Gene Expression Profiles 1.0 2.79013 Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1397 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17764 lateral parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16878 NACC1 ChEA Transcription Factor Targets 1.0 null HOXD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12742 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.68706 ARHGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22357 intermediate stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04444 Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93312 liver disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.064973 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892811 induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10303 intermediate stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.212 MYC-19079543-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null TPD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01025 BEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36886 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0498 Entorhinal area, medial part, dorsal zone, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51734 EVA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85231 GSE135514_2_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF614 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 PPIP5K1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71387 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.3438 Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1393 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.985953 HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.43014 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7047 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7795 Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM210B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97157 cerebellar nuclei of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07894 NALM16 DepMap CRISPR Gene Dependency 1.0 2.9323 IMR32 DepMap CRISPR Gene Dependency 1.0 2.18794 Symplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.902 496100356_TCx_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18417 SSC4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29846 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35903 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.56224 SNU668 CCLE Cell Line Gene CNV Profiles 1.0 2.09801 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null PPP2R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93935 DNASE1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56096 GNA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69803 COX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33278 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_28_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16878 FTC133 CCLE Cell Line Gene Expression Profiles 1.0 1.96361 Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01378 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1637 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE71468,GSE76476_0_v_1_rbfox1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE211286_7_v_5_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE135514_8_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null RERE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21655 SHF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69478 Brain Lower Grade Glioma_LGG_TCGA-DB-A64S-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10303 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22885 COLO684 DepMap CRISPR Gene Dependency 1.0 2.22952 r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31054 ZSCAN5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53968 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01867 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.873677 ZNF684 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20179 PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1236 NCIH727 CCLE Cell Line Gene Expression Profiles -1.0 -1.70012 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975249 KYAE1 DepMap CRISPR Gene Dependency 1.0 4.32875 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38515 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MANBAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17159 TTLL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86828 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29253 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2423 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11155 APEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46298 Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34632 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10462 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59005 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7433 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 NUDT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2198 abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.231169 GSE139016_3_v_2_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.694 PYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02779 paraventricular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09631 KIFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50637 Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8F_Het1A-GATA6_2d_5x_closed-Nearest_Ensembl_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14268 CDV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48622 SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -2.51251 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.045797 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59826 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.90772 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3818 mantle zone of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30534 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92794 GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53777 GRHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2013 GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.694 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937439 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09712 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22885 GSE235550_1_v_0_hspa9_human RummaGEO Gene Perturbation Signatures 1.0 null ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RVH421 DepMap CRISPR Gene Dependency 1.0 2.59068 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1953 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5355 septopallidal core nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54371 paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88176 ZMYM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80734 Field CA1, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01216 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.873677 ZNF605 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18337 Brain Lower Grade Glioma_LGG_TCGA-DU-7019-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC36A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46821 KLF7_KO_GDS2069_68_mouse_olfactory epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP1R1A_KO_GDS1920_708_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54463 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.16147 layer 5 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12856 MECP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.602 rostral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41825 CRTC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17029 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16936 Field CA1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03425 arteries GAD Gene-Disease Associations 1.0 null adult retina HPM Cell Type and Tissue Protein Expression Profiles -1.0 -0.999801 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7878 paralemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.41464 r5 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85821 KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.8411 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null coronary artery disease GWASdb SNP-Disease Associations 1.0 0.672656 HDAC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STYX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78211 E2A_Deficiency_GDS5084_271_mouse_DN2 thymocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SIPA1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62621 SCH DepMap CRISPR Gene Dependency 1.0 2.69736 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -1.57538 deltaEF1 MotifMap Predicted Transcription Factor Targets 1.0 null ERBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5018 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.5441 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null MANEAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89617 infertility GWASdb SNP-Phenotype Associations 1.0 0.574011 496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.62962 MAP3K4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49255 MALME3M DepMap CRISPR Gene Dependency 1.0 5.60913 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 PSENEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0363 Intracranial aneurysm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26354 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE84462,GSE84762_0_v_7_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.4 reticular formation of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00469 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.03308 NANOG ChEA Transcription Factor Targets 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71415 FOXB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21957 GSE250089_0_v_3_epcam_human RummaGEO Gene Perturbation Signatures -1.0 null medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45834 WM115 CCLE Cell Line Gene CNV Profiles -1.0 -1.49641 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30533 anterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29109 Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27462 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9457 CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7582