association	dataset	threshold value	standardized value
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.654
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163282_0_v_5_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8524
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6317
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.937
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4583
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.93
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.364
SUV39H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85478
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.654
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5388
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17093
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153662,GSE153664_1_v_0_zeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_1_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5109
GSE162015_1_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38092
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83057
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4315
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.9459
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38236
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8226
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6064
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9822_KD_RUNX1_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.72939
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233679_5_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5374
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29384
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0945
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24527
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4884
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9207
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9137
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7704
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.3974
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7113
GSE197562_1_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.0387
GSE128730_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0081
MOSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08974
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2308
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4692
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3297
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7436
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7597
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7088
APPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13722
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3574
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4258
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3769
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.5839
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.7805
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6645
GSE193751_1_v_3_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.255
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.073
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5021
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.7003
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1738
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99433
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1718
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3185
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.851
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.5862
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0181
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.201
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14779_KO_PGRB_SRP309208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.56862
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1735
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1341
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0918
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.654
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1437
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.811
GSE149075_2_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0446
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0536
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233441_1_v_0_tnnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17819
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8776
GSE182680,GSE182683_0_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null