association	dataset	threshold value	standardized value
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.993788
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.899456
Multiple system atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
Hereditary spherocytosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25044
ESR1	ChEA Transcription Factor Targets	1.0	null
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00081
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061917
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837439
Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29124
Parkinson disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07638
familial hyperlipidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312827
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92608
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83729
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860551
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
POLR2A	ENCODE Transcription Factor Targets	1.0	null
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26779
Intercalary meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43707
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20788
abnormality of the musculature of the neck	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
HS729	CCLE Cell Line Gene Expression Profiles	-1.0	-3.12779
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908329
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18358
GSE155087_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5794
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03541
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92041
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.46496
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TX-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.419517
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.052672
tg6	GeneRIF Biological Term Annotations	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20489
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.218
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72223
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28904
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05067
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.48463
av3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.205
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03876
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28278
kidney disease	GWASdb SNP-Disease Associations	1.0	0.848917
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03034
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GATA2	ChEA Transcription Factor Targets	1.0	null
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910884
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46021
Gait Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97315
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
Ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21541
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1669
prethalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04191
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26065
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847631
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69747
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.38521
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2051
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
Transglutaminase-like	InterPro Predicted Protein Domain Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31784
ae3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38688
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NHDF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32606
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16544
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115996
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053095
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54912
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73074
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dentate gyrus HICAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1684
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57479
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.4086
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8783
phenotype	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27146
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11094
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.816542
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45068
intermediate stratum of p3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10261
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
craniofacial dystonia	HPO Gene-Disease Associations	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212761
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31143
SW-403 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
Cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.723
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60777
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07409
cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.801974
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894834
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07463
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3158
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16096
PANC0813	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79554
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.56261
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42834
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.60412
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063166
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13802
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34021
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43479
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97216
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21719
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.94854
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5973
PMC7068927-12885_2020_6709_MOESM1_ESM.docx-2-TCF12_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71111
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
KCNC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57612
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5944
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62399
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25854
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32092
toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.617796
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99515
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Unnamed_8_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Episodic ataxia type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
vascular disease	GWASdb SNP-Disease Associations	1.0	0.080702
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81965
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.17629
dentatorubral-pallidoluysian atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.74761
mantle zone of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15154
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3519
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72964
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94765
Spinocerebellar ataxia type 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.491
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64318
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874011
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63828
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14678
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54732
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
KDM5A	ENCODE Transcription Factor Targets	1.0	null
HEC59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48754
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69067
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.752247
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76755
ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373868
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23003
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07748
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90583
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.0921
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62279
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78575
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35685
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52221
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11121
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951684
CCK81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62779
PEER	CCLE Cell Line Gene Expression Profiles	1.0	2.02333
family	GeneRIF Biological Term Annotations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054504
X-linked spinocerebellar ataxia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
skin	GTEx Tissue Gene Expression Profiles	1.0	1.92242
CAL78	DepMap CRISPR Gene Dependency	1.0	2.66886
Immunoglobulin E-set	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5583-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1239
Pernicious anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35045
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.2385
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.07709
biofilm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051641
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66704
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	2.31913
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
Mononeuritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
PLBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6722
cation binding	GO Molecular Function Annotations 2015	1.0	null
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47916
Pseudobulbar Palsy	DisGeNET Gene-Disease Associations	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08691
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15623
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11062
HPAC	CCLE Cell Line Gene Expression Profiles	1.0	1.57168
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05564
Autosomal recessive cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
SNU46	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74156
subcellular	GeneRIF Biological Term Annotations	1.0	null
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.73212
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
specific	GeneRIF Biological Term Annotations	1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZN-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.39257
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
PEX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12123
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18778
Status epilepticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
PRKRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9559
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68733
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07409
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27443
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC29A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92973
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0922
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08927
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6751
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4022
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71266
Cerebellar disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.19315
ataxia	GeneRIF Biological Term Annotations	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.959796
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61215
polyq	GeneRIF Biological Term Annotations	1.0	null
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	2.55554
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Erythroid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Hepatoma ascites cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
OACP4C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25678
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57138
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80324
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051044
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.61386
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078088
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.146
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859207
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30059
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03429
babinski sign	HPO Gene-Disease Associations	1.0	null
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25609
dementia	GWASdb SNP-Disease Associations	1.0	0.470241
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Machado-Joseph disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.903
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10318
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.643
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.064347
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.910934
MEL-JUSO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4847
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34539
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072486
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91975
HDAC2	ENCODE Transcription Factor Targets	1.0	null
plasma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176896
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.984342
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14239
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58305
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
vagina	HPA Tissue Protein Expression Profiles	1.0	1.70014
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
interalphainhibitor	GeneRIF Biological Term Annotations	1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36244
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48746
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844018
acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301054
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11127
PMC10493031__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
nine	GeneRIF Biological Term Annotations	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053791
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.916913
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.433772
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31841
RH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.191456
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EGFR_drugactivation_30_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.12889
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71229
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.200322
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.54962
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1234
Lambert-Eaton myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8216
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5274
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42116
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838642
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969186
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84733
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8331
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.05206
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108394
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
improved glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39898
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
sequencing	GeneRIF Biological Term Annotations	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-SOX14-sequence_name_SOX14	Rummagene Transcription Factor Associations 2026	1.0	null
LS513	CCLE Cell Line Gene Expression Profiles	1.0	1.71309
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077973
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07409
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54316
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69558
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23479
tauopathy	GWASdb SNP-Disease Associations	1.0	1.37327
who	GeneRIF Biological Term Annotations	1.0	null
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.112134
pace of progression	HPO Gene-Disease Associations	1.0	null
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36702
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0679
decreased	GeneRIF Biological Term Annotations	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95417
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36924
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TPRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.804
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81977
MTMR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29463
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2174
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47258
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
TRIM28	ChEA Transcription Factor Targets	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5048
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82138
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87035
hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	2.02168
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15583
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175873
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.213494
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7474
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
PLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52785
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78593
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
TRIM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19522
PAQR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50302
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929451
clinical modifier	HPO Gene-Disease Associations	1.0	null
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66477
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09641
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
L-Glutamine	DrugBank Drug Targets	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05846
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44802
Transglutaminase, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0601
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09842
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86704
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.959
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4566
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15643
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56815
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052181
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.1135
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54223
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dystonia	HPO Gene-Disease Associations	1.0	null
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.12157
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69154
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840587
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36749
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03007
NH12	DepMap CRISPR Gene Dependency	1.0	3.04285
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8413
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14275
PAX5	ENCODE Transcription Factor Targets	1.0	null
tg3	GeneRIF Biological Term Annotations	1.0	null
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93881
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4331
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09842
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8717
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849367
Parkinsonian disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86601
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052292
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28275
PMC12216985-41598_2025_7147_MOESM1_ESM.pdf-40-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30726
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39932
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.44822
ROS50	DepMap CRISPR Gene Dependency	1.0	3.51829
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77178
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81097
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86495
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive spinocerebellar ataxia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
PMC9386181-Table5.XLSX-BFT-Unnamed_1_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62258
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8096
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8805
IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.22
autoantibodies	GeneRIF Biological Term Annotations	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73374
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11561
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_FOXJ2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04943
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0767
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-339-RBPJ_RBPJ	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0013
UOK101	DepMap CRISPR Gene Dependency	1.0	2.43764
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3544
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
SKOV3	DepMap CRISPR Gene Dependency	1.0	2.76682
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.268
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4249
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50345
Ammonia	HMDB Metabolites of Enzymes	1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.55927
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
Amyotrophic Lateral Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048257
feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
Polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63754
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1768
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8518
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36737
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
physical disorder	GWASdb SNP-Disease Associations	1.0	0.375297
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63899
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69457
Autoimmune thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58007
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3535
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95456
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907302
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38132
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Limbic encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06749
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11021
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65949
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.20997
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14275
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93288
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79562
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07132
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97542
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14021
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45016
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6316
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826241
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949152
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29421
RH18	CCLE Cell Line Gene CNV Profiles	1.0	1.38592
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72024
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79412
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959624
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	2.4005
PMC11513043-41525_2024_436_MOESM1_ESM.pdf-79-TGIF1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36879
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4771
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.40401
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04191
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.71069
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96692
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052302
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0572
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83226
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0959
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
ZNF723	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55487
sensitivity	GeneRIF Biological Term Annotations	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
CTAGE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34157
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053295
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
NAA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15753
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928599
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive spinocerebellar ataxia 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
kb cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.470763
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.55857
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94331
incoordination	HPO Gene-Disease Associations	1.0	null
psoriasis	GWASdb SNP-Disease Associations	1.0	0.826866
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF394	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49514
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74972
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
c1528gc	GeneRIF Biological Term Annotations	1.0	null
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.63875
enabling	GeneRIF Biological Term Annotations	1.0	null
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10532
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9294
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50104
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
Gluten allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21507
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18806
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39493
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15978
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.743226
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Spinocerebellar ataxia with axonal neuropathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.637
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.55927
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94787
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30851
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079583
Regio parietalis capitis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62743
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nrf2_deficiency_GDS3406_156_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAP4K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58107
syt14	GeneRIF Biological Term Annotations	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961274
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dizziness	GeneRIF Biological Term Annotations	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.52
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53428
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35739
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046868
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Calcium	HMDB Metabolites of Enzymes	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transglutaminase, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958592
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34957
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.419
Lung squamous cell carcinoma_LUSC_TCGA-66-2767-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905852
cellular process	GO Biological Process Annotations 2015	1.0	null
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01241
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16007
NB10	DepMap CRISPR Gene Dependency	1.0	5.02835
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Benign familial infantile epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
diseases	GeneRIF Biological Term Annotations	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.872941
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
PMC4366019-pone.0116096.s005.xlsx-Primary_positives_NOT_retested-Primary_S6P_positives_NOT_selected_for_retesting_with_the_4_individual_RNAi_used_in_the_intial_screen_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.180996
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inflammatory abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.275416
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72709
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	3.36836
way	GeneRIF Biological Term Annotations	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21507
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09641
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
prethalamic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76755
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
basal plate of p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06995
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045516
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15623
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051529
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5199
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947093
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57858
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28493
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.016
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4651
causing	GeneRIF Biological Term Annotations	1.0	null
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9889
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05818
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19948
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85933
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16707
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
L-Glutamine	HMDB Metabolites of Enzymes	1.0	null
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85415
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997016
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
kidney cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2728
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.796874
Cerebral Atrophy	DisGeNET Gene-Disease Associations	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62439
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5594
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.3314
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900775
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	9.78921
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01028
integumentary system disease	GWASdb SNP-Disease Associations	1.0	0.150953
one	GeneRIF Biological Term Annotations	1.0	null
MACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08599
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02153
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.433021
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46821
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0353
CHP-134	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46955
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67525
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12328
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18108
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11121
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.189593
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
HS746T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GRM	CCLE Cell Line Gene CNV Profiles	1.0	1.57714
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040688
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04571
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.265
affordable	GeneRIF Biological Term Annotations	1.0	null
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84112
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99651
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9234
Glutamate decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30381
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4092
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840047
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.849725
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08404
Transglutaminase, N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.115692
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26066
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3242
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.930242
GLB1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88995
Multifocal dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11561
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.44502
Cerebellar ataxia type 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
basis	GeneRIF Biological Term Annotations	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1961
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34184
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943383
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41322
prosomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19049
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.89454
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08616
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4158-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34575
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03298
NCI-H1341	COSMIC Cell Line Gene Mutation Profiles	1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18395
peptide cross-linking	GO Biological Process Annotations 2015	1.0	null
P-388D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.040465
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88344
TGFBR2_knockout_293_GSE46211	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.91306
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9934
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
FAM171A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69833
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
herpetiformis	GeneRIF Biological Term Annotations	1.0	null
decreased circulating serum albumin level	MGI Mouse Phenotype Associations 2023	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28914
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48195
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064221
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.362628
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57382
Polycythemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0469
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
Dermatitis herpetiformis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.85
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.70014
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91189
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47151
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50479
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92318
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01519
T84	CCLE Cell Line Gene Expression Profiles	1.0	1.40681
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.70014
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.093706
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19076
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7394-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18614
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7401
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21507
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10697
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.816542
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84924
stroke	GAD Gene-Disease Associations	1.0	null
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88516
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Slow Progression	DisGeNET Gene-Phenotype Associations	1.0	null
dermatitis herpetiformis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.766759
members	GeneRIF Biological Term Annotations	1.0	null
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8436
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35045
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15296
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08895
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42834
Trabecula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196849
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059686
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879387
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.167169
KML1	DepMap CRISPR Gene Dependency	1.0	10.4672
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84094
Autosomal dominant cerebellar ataxia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Aspartate carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38171
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043687
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73603
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044131
whole	GeneRIF Biological Term Annotations	1.0	null
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.800744
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
Neck Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
u-266 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.620621
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chitin-based extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.827
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21949
gluten	GeneRIF Biological Term Annotations	1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1363
SNU324	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85498
Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alzheimer's disease (cognitive decline)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
neck muscle weakness	HPO Gene-Disease Associations	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17629
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04043
intention tremor	HPO Gene-Disease Associations	1.0	null
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907838
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05067
Cerebellar ataxia type 43	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74839
Lung squamous cell carcinoma_LUSC_TCGA-94-8490-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.65525
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53423
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.456
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168349
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040944
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55482
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71178
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35685
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59131
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5323-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proportions	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_6_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78127
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
FAM136A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19352
spinocerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31624
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.70014
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12863
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.12737
RUNX1_01_344	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.63275
Torticollis	DisGeNET Gene-Phenotype Associations	1.0	null
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
appear	GeneRIF Biological Term Annotations	1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907838
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057492
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6744
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.82278
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60651
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02524
wholeexome	GeneRIF Biological Term Annotations	1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5122
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926526
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13741
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18894
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11139
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102572
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935744
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45047
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11121
perilemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56322
lend	GeneRIF Biological Term Annotations	1.0	null
tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539793
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63011
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orofacial cleft	GWASdb SNP-Disease Associations	1.0	0.700141
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
MAFK	ENCODE Transcription Factor Targets	1.0	null
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
spinocerebellar ataxia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907302
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.385
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097703
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32909
Spinocerebellar ataxia type 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53019
SVBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72303
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18772
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168101
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.56879
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047967
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.093238
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11965
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09549
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844148
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMARCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98444
tegmental field of p3 (Forel's field)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18038
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32589
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.66413
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0858
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
ELF1	ENCODE Transcription Factor Targets	1.0	null
SYCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50365
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393374
MAP3K12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62414
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06047
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053899
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.729762
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
CADM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75142
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.930019
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14246
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77711
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18247
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052652
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71919
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20271
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140305
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62066
neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.318407
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spinocerebellar ataxia type 26	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.472
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.7565
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84484
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086223
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61001
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101323
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Cerebellar ataxia type 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
Autoimmune epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53538
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.29439
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112175
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1992
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18561
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.653
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12146
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.234225
OCILY19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72027
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91231
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067442
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
A673	DepMap CRISPR Gene Dependency	1.0	2.39281
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16179
mantle zone of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03062
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	2.03076
GSE95771_0_v_2_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884681
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
genome	GeneRIF Biological Term Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35538
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14386
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09886
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01654
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852811
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950097
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878552
large	GeneRIF Biological Term Annotations	1.0	null
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
gba2	GeneRIF Biological Term Annotations	1.0	null
FFAR4_KO_GDS4811_507_mouse_adipose	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0265
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1135
TP53	ChEA Transcription Factor Targets	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066875
metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
RUNX3	ENCODE Transcription Factor Targets	1.0	null
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15583
transglutaminase	GeneRIF Biological Term Annotations	1.0	null
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55207
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00958
HYAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24503
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.10639
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054619
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25152
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91561
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995485
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997016
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01361
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16635
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tremor	HPO Gene-Disease Associations	1.0	null
finding	GeneRIF Biological Term Annotations	1.0	null
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74353
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64378
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1263
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
transferase activity, transferring acyl groups	GO Molecular Function Annotations 2015	1.0	null
Spinocerebellar ataxia type 31	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
showed	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32507
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97059
JHOS4	DepMap CRISPR Gene Dependency	1.0	2.17628
Myofibrillar myopathy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27076
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958543
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38611
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62654
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.43233
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054374
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.52
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30218
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ktp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699853
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859207
notion	GeneRIF Biological Term Annotations	1.0	null
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
PMC11513043-41525_2024_436_MOESM1_ESM.pdf-79-TGIF1_1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
dentatorubral-pallidoluysian atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.939
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52885
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53387
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19869
RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057278
serve	GeneRIF Biological Term Annotations	1.0	null
OSTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0957
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
ICC2	DepMap CRISPR Gene Dependency	1.0	4.93831
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02676
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113556
Cerebellar Dysmetria	DisGeNET Gene-Phenotype Associations	1.0	null
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27657
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25764
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.016
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2995
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21582
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.279
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.53515
TC32	CCLE Cell Line Gene Expression Profiles	1.0	2.02681
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06848
Abnormality Of The Orbital Region	DisGeNET Gene-Phenotype Associations	1.0	null
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.103
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9305
slow progression	HPO Gene-Disease Associations	1.0	null
Spinocerebellar ataxia	ClinVar Gene-Phenotype Associations 2025	1.0	null
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81825
antibodies	GeneRIF Biological Term Annotations	1.0	null
mantle zone of p3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7802
Cerebellar Degeneration	DisGeNET Gene-Disease Associations	1.0	null
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.63617
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28594
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	2.83749
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
distribution	GeneRIF Biological Term Annotations	1.0	null
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04191
abnormality of the head	HPO Gene-Disease Associations	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
basal plate of p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76755
investigate	GeneRIF Biological Term Annotations	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50674
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060451
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1707
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040821
marker	GeneRIF Biological Term Annotations	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09641
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21719
Hyperekplexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Parenchyma of thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901605
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
against	GeneRIF Biological Term Annotations	1.0	null
targeted	GeneRIF Biological Term Annotations	1.0	null
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13382
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29407
vitro	GeneRIF Biological Term Annotations	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06613
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8314
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.707941
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
Progressive supranuclear palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51116
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51452
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.942438
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859207
Parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49162
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41268
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61522
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61248
OVMIU	DepMap CRISPR Gene Dependency	1.0	5.84197
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1194
Postaxial acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
skin disease	GWASdb SNP-Disease Associations	1.0	0.183319
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7392
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
F2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89496
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Immunoglobulin alpha deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
Miller Fisher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.09
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15859
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050994
action tremor	HPO Gene-Disease Associations	1.0	null
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83288
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58859
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive spinocerebellar ataxia 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053441
bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060183
increased susceptibility to bacterial infection	MGI Mouse Phenotype Associations 2023	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69597
superficial stratum of p3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36873
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00448
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.465
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38693
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01655
ZNF768	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74425
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	2.30448
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896578
HDAC6	ENCODE Transcription Factor Targets	1.0	null
functional motor problems	HPO Gene-Disease Associations	1.0	null
lm12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612401
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MYC	ChEA Transcription Factor Targets	1.0	null
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35346
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942432
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00871
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13775
Spinocerebellar ataxia 35	ClinVar Gene-Phenotype Associations	1.0	null
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897448
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08019
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37159
increased lean body mass	MGI Mouse Phenotype Associations 2023	1.0	null
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
DGKZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03253
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051641
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
missense	GeneRIF Biological Term Annotations	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907942
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10483
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982031
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.896827
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.536183
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
SW1990	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.791
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
Difficulty Walking	DisGeNET Gene-Phenotype Associations	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61597
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041013
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29413
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354455
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168101
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55393
POU5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71788
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04711
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6228
Yellow bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00074
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11941
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863495
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05191
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55621
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95593
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238406
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06019
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16102
Hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
Cerebellar Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37518
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68196
LARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24247
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87289
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42762
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044225
mRNA_SUZ12_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04171
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4374
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96846
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20279
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900273
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6189
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24388
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
Brain Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77351
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0079
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.016
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.55656
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH5	DepMap CRISPR Gene Dependency	1.0	3.79777
merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512564
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
NCIH441	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40432
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.58403
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40923
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92783
AMOTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01355
HSQ89	DepMap CRISPR Gene Dependency	1.0	2.08282
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.33
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863023
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997016
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6952-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
TCFL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68842
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12502
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997016
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88083
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87484
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78205
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75025
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.67381
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
PC14	CCLE Cell Line Gene Expression Profiles	1.0	1.55493
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084902
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10453
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8314-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormal Coordination	DisGeNET Gene-Phenotype Associations	1.0	null
Biotinidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5896
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
exhibited	GeneRIF Biological Term Annotations	1.0	null
TE-671 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042324
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863023
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25506
xiiia	GeneRIF Biological Term Annotations	1.0	null
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60448
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.15324
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
PRDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04936
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68864
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.90684
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IST-SL2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of coordination	HPO Gene-Disease Associations	1.0	null
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272649
Choreatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648532
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144965
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.261648
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27624
onset	HPO Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903108
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0013
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71069
Progressive Cerebellar Ataxia	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gait disturbance	HPO Gene-Disease Associations	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885673
Synaptic vesicle, resting pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
glutendependent	GeneRIF Biological Term Annotations	1.0	null
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75117
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1032
Myofibrillar myopathy 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
NCI-H69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78012
neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408592
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19595
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09156
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
Colleterial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25716
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
Action Tremor	DisGeNET Gene-Phenotype Associations	1.0	null
BL2317 (CDK5RAP2)	NURSA Protein Complexes	1.0	null
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28047
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09776
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05349
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59729
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46976
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07967
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
C84	DepMap CRISPR Gene Dependency	1.0	2.97176
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21748
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38322
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70747
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.971
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041033
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.757465
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33267
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
cas1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Spinocerebellar Ataxia	DisGeNET Gene-Disease Associations	1.0	null
spinocerebellar	GeneRIF Biological Term Annotations	1.0	null
Cerebellar ataxia type 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11996
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64415
ZDHHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075594
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1756
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.89111
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.137662
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32933
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10686
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11278
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Dysmetric Saccades	DisGeNET Gene-Phenotype Associations	1.0	null
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86994
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
TEAD4	ENCODE Transcription Factor Targets	1.0	null
abnormality of skin physiology	GWASdb SNP-Phenotype Associations	1.0	0.275416
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52002
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79696
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pair	GeneRIF Biological Term Annotations	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.086692
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0751
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50695
Autoimmune hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46874
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
OAW-28	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54462
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26319
subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535438
EJM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58886
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21063
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02518
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977354
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00442
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.093238
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95362
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218034
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07971
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12601
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15308
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32698
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
dna	GeneRIF Biological Term Annotations	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08568
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.55927
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04879
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tuberculosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043058
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Autism	DisGeNET Gene-Disease Associations	1.0	null
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09584
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12601
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.25691
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.04387
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14522
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874011
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050989
thalamic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06574
exome	GeneRIF Biological Term Annotations	1.0	null
B cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14639
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40836
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65998
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RVH421SKINFV1	DepMap CRISPR Gene Dependency	1.0	3.77813
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17179
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5078
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
Prepulse inhibition of the startle response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56519
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dysarthria	HPO Gene-Disease Associations	1.0	null
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950382
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39472
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49674
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44102
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Episodic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.84852
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive spinocerebellar ataxia 27	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
tgm6	GeneRIF Biological Term Annotations	1.0	null
Extratemporal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14844
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsal tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03062
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.171
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87806
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.496939
deletion	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867788
8305C	CCLE Cell Line Gene CNV Profiles	1.0	1.4623
AKT1_OE_GDS2308_498_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.046495
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
SEC24D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74631
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
binding	GO Molecular Function Annotations 2015	1.0	null
intermediate part of isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15154
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77855
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92356
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2198
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32
prosomere 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81779
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05417
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9241
NCIH838	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79956
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.90481
comprehensive	GeneRIF Biological Term Annotations	1.0	null
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5389
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34592
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.8684
Gluten Intolerance	DisGeNET Gene-Disease Associations	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1536
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17876
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306805
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32589
Encephalomyelitis	DisGeNET Gene-Disease Associations	1.0	null
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91561
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75065
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
neurodegenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61877
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
Wheat allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06574
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46675
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85802
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80321
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282837
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
JURL-MK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298524
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
Centronuclear myopathy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77509
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71709
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08568
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
dorsolateral (non-cerebellar) part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1528
protein-glutamine gamma-glutamyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mononeuritis multiplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
PRKCZ_KO_GDS4310_293_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0651
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
Ciliary transition fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8436
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28899
RUNX1	ChEA Transcription Factor Targets	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77738
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45372
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
PIGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77893
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
GPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70503
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47804
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052202
Babinski Reflex	DisGeNET Gene-Phenotype Associations	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27085
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62657
transferase activity	GO Molecular Function Annotations 2015	1.0	null
Spastic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05393
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19566
NCIH2085	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47806
Lung squamous cell carcinoma_LUSC_TCGA-60-2722-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5578
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05553
globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125137
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23219
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0508
DOV13	DepMap CRISPR Gene Dependency	1.0	5.82579
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10261
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054449
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DMS273	CCLE Cell Line Gene Expression Profiles	1.0	1.78542
tissue	GeneRIF Biological Term Annotations	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35685
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
Lung squamous cell carcinoma_LUSC_TCGA-85-7698-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063588
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.343
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.42577
persistence of hyaloid vascular system	MGI Mouse Phenotype Associations 2023	1.0	null
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04081
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.140305
SYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66835
identify	GeneRIF Biological Term Annotations	1.0	null
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40929
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98238
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4646
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42505
sensitive	GeneRIF Biological Term Annotations	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907838
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840868
CHL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84859
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35934
dermatitis	GeneRIF Biological Term Annotations	1.0	null
HT1197	CCLE Cell Line Gene CNV Profiles	1.0	2.19909
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961785
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
stability	GeneRIF Biological Term Annotations	1.0	null
ABC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
bc96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
Vascular parkinsonism	ClinVar Gene-Phenotype Associations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adult onset	HPO Gene-Disease Associations	1.0	null
Carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97043
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07545
Spastic ataxia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14907
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37732
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841649
cerebellar atrophy	HPO Gene-Disease Associations	1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49712
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052303
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959772
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932649
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00717
Promyelocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9286
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35343
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
BCL11A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Progressive Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2182
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
GSE104022_3_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KBTBD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53929
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48398
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1024
Spinocerebellar ataxia type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23332
KPNYS	DepMap CRISPR Gene Dependency	1.0	6.62363
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47168
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56127
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79226
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03051
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
disease	GWASdb SNP-Disease Associations	1.0	0.042281
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
Dysarthria	DisGeNET Gene-Disease Associations	1.0	null
IGFBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82788
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99627
Purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47356
TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2581
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
l5178yr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14925
Sensory peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
Multiple Sclerosis, Secondary Progressive	DisGeNET Gene-Disease Associations	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0508
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hair medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
APBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.934546
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8436
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
genetic	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE510	CCLE Cell Line Gene Expression Profiles	1.0	1.39949
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45173
LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
responses	GeneRIF Biological Term Annotations	1.0	null
generalized abnormality of skin	GWASdb SNP-Phenotype Associations	1.0	0.150203
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	1.65954
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863495
PSN1	CCLE Cell Line Gene CNV Profiles	1.0	1.54906
Cerebellar ataxia type 47	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03447
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3688
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08568
Multiple Sclerosis, Relapsing-Remitting	DisGeNET Gene-Disease Associations	1.0	null
lingual-facial-buccal dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138081
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44688
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27624
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054412
cosegregation	GeneRIF Biological Term Annotations	1.0	null
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38643
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.073242
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17284527-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.17962
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0813
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42396
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78962
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
PEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75753
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cerebellar ataxia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
IGROV1	DepMap CRISPR Gene Dependency	1.0	3.51164
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90961
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04597
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57364
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCC78	DepMap CRISPR Gene Dependency	1.0	2.03344
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75013
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63917
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44955
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059872
PMC6084392-oncotarget-09-30253-s006.xls-geneset1-TF-miRNA-net-NRL_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
cellular_component	GO Cellular Component Annotations 2015	1.0	null
multiple myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180104
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61496
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79287
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053583
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gluten Sensitivity	DisGeNET Gene-Disease Associations	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	3.24933
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.093443
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106602
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	2.89277
kinetic tremor	HPO Gene-Disease Associations	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.085699
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
Autosomal dominant cerebellar ataxia	ClinVar Gene-Phenotype Associations 2025	1.0	null
JHH2	DepMap CRISPR Gene Dependency	1.0	3.40103
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.816542
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12083
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
Friedreich ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
inner CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934728
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924544
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03196
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18395
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09748
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13847
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65884
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856282
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33114
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849044
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50217
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.4664
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.37327
NCIH2170	CCLE Cell Line Gene Expression Profiles	1.0	1.44885
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45884
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111743
Lobopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Celiac Disease	DisGeNET Gene-Disease Associations	1.0	null
Methyl coenzyme M reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
transferase activity, transferring amino-acyl groups	GO Molecular Function Annotations 2015	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
THY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06086
choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238108
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.55927
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
spinocerebellar degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.29964
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.73633
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057362
cell part	GO Cellular Component Annotations 2015	1.0	null
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20004
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pyrroline-5-carboxylate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997016
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurodegenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97902
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931677
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K029AX	DepMap CRISPR Gene Dependency	1.0	3.38163
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08616
Actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.871
Hereditary ataxia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16199
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11561
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27443
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4535
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5127
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
all	HPO Gene-Disease Associations	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Axonal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60162
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2053
Stiff-Person syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
L-1210 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
Theca externa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
focal dystonia	HPO Gene-Disease Associations	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1967
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39957
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	4.74125
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.14226
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044972
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74096
AKT1_OE_GDS2308_499_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95653
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53538
Immunoglobulin-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autoimmune	GeneRIF Biological Term Annotations	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3517
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3439
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949152
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SUIT2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53527
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
AKT1_Activation - 6 week induction_GDS2308_718_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53538
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15274
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
alar plate of p3 (alar prethalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04191
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39924
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
C3A	CCLE Cell Line Gene CNV Profiles	1.0	1.34575
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43237
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85229
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5391
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20954
X-linked cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
spinocerebellar degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cofilin-actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
defined	GeneRIF Biological Term Annotations	1.0	null
Alzheimer's disease (cognitive decline)	GWAS Catalog SNP-Phenotype Associations	1.0	0.389385
Boucher-Neuhauser syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44878
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01305
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14692
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31892
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87733
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66988
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07113
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27443
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04239
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21719
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.55927
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17551
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
Mononeuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
technologies	GeneRIF Biological Term Annotations	1.0	null
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83384
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2984
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17794
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAXE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85341
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4892-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85855
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6159
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39121
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75576
PMAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90098
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0085
all	GeneRIF Biological Term Annotations	1.0	null
ano10	GeneRIF Biological Term Annotations	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21079
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05212
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12017
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07808
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
abnormality of the neck	HPO Gene-Disease Associations	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15106
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37437
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2314
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27975
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09641
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28351
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83135
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65873
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07409
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61482
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27624
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.662742
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61766
PAX6	ChEA Transcription Factor Targets	1.0	null
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21507
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
Polyneuropathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18039
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28151
Intranuclear rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72336
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26761
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93218
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80038
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04711
Cardiac Arrest	DisGeNET Gene-Disease Associations	1.0	null
brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.690293
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
muscle weakness	HPO Gene-Disease Associations	1.0	null
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Centronuclear myopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
SOX2	ChEA Transcription Factor Targets	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12402
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.84991
Cerebellar Purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.816
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
torticollis	HPO Gene-Disease Associations	1.0	null
laminin-6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.776909
analyzed	GeneRIF Biological Term Annotations	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BE2-M17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
superficial stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15623
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0135
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
Hemidystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97295
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44878
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64922
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.825268
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05136
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Field CA2, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04571
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2641
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46313
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11204
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092585
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90722
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
oral cleft	GWASdb SNP-Phenotype Associations	1.0	0.60143
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.56006
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.593072
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
BACE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45814
RBBP5	ENCODE Transcription Factor Targets	1.0	null
myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155692
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
stroke	GWASdb SNP-Phenotype Associations	1.0	0.608869
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
biological_process	GO Biological Process Annotations 2015	1.0	null
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21748
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27146
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13815
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
PATU8988S	CCLE Cell Line Gene Expression Profiles	1.0	1.81205
credence	GeneRIF Biological Term Annotations	1.0	null
diencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24132
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97902
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8547
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17887
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30242
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053869
psoriasis	GWASdb SNP-Phenotype Associations	1.0	0.721729
CMK115	DepMap CRISPR Gene Dependency	1.0	2.77731
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Genital chamber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4719
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.2931
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55352
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNYN	DepMap CRISPR Gene Dependency	1.0	3.90072
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3858
cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.817565
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042562
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055761
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.675
CWC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61678
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907209
tg88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.526
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30301
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.37604
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
illustrates	GeneRIF Biological Term Annotations	1.0	null
bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824013
TMEM205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98597
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98974
rapid	GeneRIF Biological Term Annotations	1.0	null
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
Stroke	dbGAP Gene-Trait Associations	1.0	0.084686
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.97806
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43968
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.49566
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248203
Cerebellar Ataxia	HuGE Navigator Gene-Phenotype Associations	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.20668
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
OSRC2	CCLE Cell Line Gene CNV Profiles	1.0	1.64412
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
D502MG	DepMap CRISPR Gene Dependency	1.0	2.28546
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08608
AN3CA	CCLE Cell Line Gene Expression Profiles	1.0	1.75661
CTCF	ENCODE Transcription Factor Targets	1.0	null
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6496
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20075
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89248
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01591
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98719
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76755
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
ARO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15074
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23221
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54147
head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.81983
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
intracellular part	GO Cellular Component Annotations 2015	1.0	null
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44095
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19869
abnormality of the mouth	GWASdb SNP-Phenotype Associations	1.0	0.148467
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17247
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	0.883754
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14218
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13935
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.170666
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05314
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52878
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02113
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.958135
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0701
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907302
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14098
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921756
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59729
Ataxia	DisGeNET Gene-Disease Associations	1.0	null
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Mononeuritis of upper limb and mononeuritis multiplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12234
colon	HPA Tissue Protein Expression Profiles	-1.0	-0.816542
HTC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78183
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	1.19958
NB6	DepMap CRISPR Gene Dependency	1.0	6.57005
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46144
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.315212
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68733
LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
causative	GeneRIF Biological Term Annotations	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21507
GSE173201_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.606333
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34914
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF827	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75965
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
neurological	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12418
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89743
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
Autosomal recessive spinocerebellar ataxia 31	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Protein-glutamine gamma-glutamyltransferase, eukaryota	InterPro Predicted Protein Domain Annotations	1.0	null
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
NB69	DepMap CRISPR Gene Dependency	1.0	2.1397
gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378748
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.634349
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
artery disease	GWASdb SNP-Disease Associations	1.0	0.112518
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0085
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.62674
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65888
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6957
gluteninduced	GeneRIF Biological Term Annotations	1.0	null
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4742
Neuromuscular junction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6751
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Multiple carboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11971
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052134
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19049
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
Methane monooxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4634-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.040263
ZSCAN26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10153
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09011
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82998
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3194
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ataxia	HPO Gene-Disease Associations	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067771
subgroup	GeneRIF Biological Term Annotations	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.057262
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874011
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888745
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72292
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.139485
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.17827
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062366
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12012
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5308
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077871
MCAS	CCLE Cell Line Gene Expression Profiles	1.0	1.58308
abnormality of movement	HPO Gene-Disease Associations	1.0	null
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89666
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27312
GSE207853_2_v_0_mafg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98237
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
COX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25957
Tripartite ATP-independent periplasmic transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01377
Brockmann body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.485505
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.1709
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86625
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.825
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837088
Nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
Guillain-Barre syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14471
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
Autoimmune neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55468
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.10068
L3MBTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78113
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55554
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
mRNA cleavage stimulating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74206
KARPAS422	DepMap CRISPR Gene Dependency	1.0	2.56165
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49014
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4 neuroglioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91683
OSC-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Moderate Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52822
PPARD	ChEA Transcription Factor Targets	1.0	null
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05985
Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.90816
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63136
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53425
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0886
spinocerebellar ataxia 35	OMIM Gene-Disease Associations	1.0	null
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04994
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9306
Autoimmune disease of peripheral nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7722
dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112123
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
NCIH23	CCLE Cell Line Gene Expression Profiles	1.0	1.69823
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09535
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46264
sperm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091259
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7997-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.47621
difficulty walking	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13111
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5654
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
Cerebellar Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11121
mutants	GeneRIF Biological Term Annotations	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874011
affected	GeneRIF Biological Term Annotations	1.0	null
gamma-glutamyl transpeptidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
SPI1	ENCODE Transcription Factor Targets	1.0	null
hyperreflexia	HPO Gene-Disease Associations	1.0	null
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58551
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55221
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.55712
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.254
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04617
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837439
cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.510728
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30501
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2182
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07582
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.85185
neurological speech impairment	HPO Gene-Disease Associations	1.0	null
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42327
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.054
Multiple Sclerosis, Primary Progressive	DisGeNET Gene-Disease Associations	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054824
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48986
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33087
Inherited Acute Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744