association	dataset	threshold value	standardized value
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.04242
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.261
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03724
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paroxetine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218356
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03258
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Spotted fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE194128_1_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4507
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.558
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.60763
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56026
BPH1	DepMap CRISPR Gene Dependency	1.0	2.12502
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222331
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41465
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0991
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2398
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_10_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74357
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TC71	DepMap CRISPR Gene Dependency	1.0	4.03876
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02808
Rotigotine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
BHY	DepMap CRISPR Gene Dependency	1.0	2.03114
GSE151612_0_v_10_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCI4B	DepMap CRISPR Gene Dependency	1.0	8.67424
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OP-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3507642-1471-2164-13-355-S4.xlsx-direct_AR-repression_Cmpd30-UP-HUGO_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPrEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
Human - Tonsil - L2 - MBC derived IgG+ PC	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04301
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	2.96172
GLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1114
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7209
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66705
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.666951
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08609
JHU022	DepMap CRISPR Gene Dependency	1.0	10.6853
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89045
Boutonneuse fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8398
D542MG	DepMap CRISPR Gene Dependency	1.0	2.97504
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.74547
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7558
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6188
SR 27897	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	2.44413
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.70969
IMR32	DepMap CRISPR Gene Dependency	1.0	3.25687
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37004
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0854
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19328
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202037
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207364
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408464
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4341
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFPS	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28341
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22741
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
HA-22-CY42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227388
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.9244
NCIH661	DepMap CRISPR Gene Dependency	1.0	2.24852
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8175
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2663
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1764
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr1_95116646_T_C_b38	GTEx eQTL 2025	1.0	1.06144
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02328
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10739
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54413
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47085
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268054
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.309
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23744
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7974
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15497
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SHP77	DepMap CRISPR Gene Dependency	1.0	2.46484
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.0026
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.95
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0499
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.58454
Xia-Gibbs Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1985
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06142
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05133
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CALU6	DepMap CRISPR Gene Dependency	1.0	2.82879
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15354
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127916_1_v_2_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4927
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14769
GSE126402_1_v_6_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15877
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Erythroid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24314
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5287
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7825356-8844261.f3.docx-128-ZNF326_ZNF326	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206108_1_v_0_bhlhe22_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.4916
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397822
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04122
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.735
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217248
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237266
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03498
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Nilotinib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188854
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKNMM	DepMap CRISPR Gene Dependency	1.0	2.42736
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6174
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204771
8305C	DepMap CRISPR Gene Dependency	1.0	2.43362
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201973
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1172
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419462
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59913
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306232
GSE196962_4_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217452_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	0.768451
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.581
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13589
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52801
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110708_2_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3686
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_29_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169205_0_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6779
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ND-15-RC31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20222
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08105
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39577
10074-G5	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2393
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36804
CASKI	DepMap CRISPR Gene Dependency	1.0	2.94128
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290689
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44029
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2016
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3108
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4972
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1142
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.176
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.02334
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.82666
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135352_2_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6845
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12202
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54351
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208198
ADNP-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCM1	DepMap CRISPR Gene Dependency	1.0	6.66078
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.30798
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02293
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Human - Liver - L2 - HSC	HuBMAP Azimuth Cell Type Annotations	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4775
GSE102870_1_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7519331-pnas.1921408117.sd18.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Tic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	2.6162
GSE181959_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LCLC103H_LUNG	CCLE Cell Line Proteomics	1.0	2.83874
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249569_1_v_0_ncapd3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312442
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.2229
K562_KW-2449_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159734
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12783
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9086
A253	DepMap CRISPR Gene Dependency	1.0	3.24806
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.789303
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126402_1_v_3_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.912592
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20212
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.97632
PMC9314667-Table_1.xlsx-Regulons-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0235
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181521_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.1279
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Human - Bone Marrow - L2 - Late Erythroid	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22944
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7734
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211594
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351456
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474251
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84437
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KB-46-EJ60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251019
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_3_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0094
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-5-HEY2_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
BB-42-FF52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255989
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13627
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382009
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0952
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6087
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15188
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0832
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.7989
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.367
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203769
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
LUBIPROSTONE	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37655
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMG1	DepMap CRISPR Gene Dependency	1.0	3.53739
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0722
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22582
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.511
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
Compound-1a	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5933
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26267
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214601
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31789
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04717
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00251
GSE210885_5_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Erythroid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229783
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61893
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82291
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24896
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236072,GSE236075_2_v_1_ccr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DA-69-UN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290549
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8346
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5993
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20718
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE149075_8_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNUC5	DepMap CRISPR Gene Dependency	1.0	4.47973
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6674
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4289
FB-39-CW59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286314
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77084
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.19761
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.861
D502MG	DepMap CRISPR Gene Dependency	1.0	2.97419
VP229	DepMap CRISPR Gene Dependency	1.0	2.34489
GSE110708_0_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41831
A-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	3.5902
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27385
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0712
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241333
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351474
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56215
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214931_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s002.xlsx-MITF_DOWN_in_30kb-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17502
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07892
Tanomastat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_5_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3430588-1477-3155-10-16-S8.pdf-6-TBX15_TBX15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310566
K562_Nilotinib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158299
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
PMC11216188-peerj-12-17616-s013.pdf-16-DR1_DR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1882
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17867
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24661
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28789
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20577
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6899
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3667
AD-51-FB60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459007
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27987
GSE249098_3_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273581
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238262
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5437
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355165
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10375
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26764
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3582
Histiocytic lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5106
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7418
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPB06189	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Clozapine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08889
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102870_1_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16128
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-47-ZNF326_ZNF326	Rummagene Transcription Factor Associations 2026	1.0	null
Palmitic acid (16:0) levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3087
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.536353
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UTP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0297
CA-42-YI34_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22974
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05434
CHEMBL1348080	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206784_2_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01585
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488676
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442473
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390617
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ethiprole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6389
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ro 28-1675	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1071
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3685
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.58516
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Tozasertib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177589
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0126
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180468_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1057
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.61111
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58072
Eltrombopag	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AU565_BREAST	CCLE Cell Line Proteomics	1.0	8.33941
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223554
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2461
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1478
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00048
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8874
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39751
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE204832_0_v_1_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7821
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SB 699551	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
HMB-Val-Ser-Leu-VE	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.61
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26451
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stearic acid (18:0) levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7699
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8617
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14135
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_3_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-13_CD7_CD1a_DEG-DEG_L2FC_1_0_FDR_0_05_REL	Rummagene Transcription Factor Associations 2026	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6277
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200433
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202893
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203056
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
chr1_95241661_C_T_b38	GTEx eQTL 2025	1.0	2.62255
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46335
KYSE220	DepMap CRISPR Gene Dependency	1.0	6.0392
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_5_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.907
UMI-77	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220906
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
HEY	DepMap CRISPR Gene Dependency	1.0	2.61948
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320966
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4060771-170289.f1.pdf-336-IRX4_IRX4	Rummagene Transcription Factor Associations 2026	1.0	null
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.355
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35362
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71551
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7519331-pnas.1921408117.sd11.xlsx-ERM_OMM_DualBiotinylated_APEXSq-Ensembl_Gene_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Caffeine consumption from coffee	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17236
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4619
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatic stellate cell_Liver_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8773
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.79702
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10334
COGN305	DepMap CRISPR Gene Dependency	1.0	4.69995
Gilles de la Tourette syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4256
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154658
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247230_0_v_1_anp32b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4179
PMC11960529-mmc4.xlsx-Atrial_LHX2_KOoverCT-gene_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23884
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425466
GSE166536_0_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OSC20	DepMap CRISPR Gene Dependency	1.0	3.04595
STK869906	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.47
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116894_1_v_0_tle3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231891_3_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bipolar disorder (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8002
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20901
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48507
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_1_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	4.13225
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	2.42092
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2442
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312464
K562_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141086
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373925
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5743
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE191015_1_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKNAS_AUTONOMIC_GANGLIA	CCLE Cell Line Proteomics	1.0	8.75057
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RH41_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	4.26507
SNU119_OVARY	CCLE Cell Line Proteomics	1.0	2.48769
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UDP-N-acetylglucosamine transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2028
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9853
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7651
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04317
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18941
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-f_CEBPA_DEGs-Gene_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470172
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38454
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1155
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_2_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20074
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04833
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	2.10861
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120489
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02199
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2344
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.30182
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.60843
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64414
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26507
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-61-OO16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234676
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265002
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7853
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.43413
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.183
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
Adverse response to drug	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
GSE139948_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102870_5_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epidermal lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48521
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157233_1_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403454
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Flavopiridol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.65
GSE88819_6_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CALU1	DepMap CRISPR Gene Dependency	1.0	2.16931
AB-71-CI37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220786
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221844
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239213
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44131
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209582_1_v_0_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354658
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71296
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-01-UN23_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271315
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.54985
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93156_1_v_0_idelalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PC3_PROSTATE	CCLE Cell Line Proteomics	1.0	2.62118
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57999
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
YWHAG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26239
chr1_95200088_G_A_b38	GTEx eQTL 2025	1.0	3.17484
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10653
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465185
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS729	DepMap CRISPR Gene Dependency	1.0	2.27788
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277673
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69262
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0079
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18328
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48737
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0849
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202676
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200919
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24431
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65993
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sertoli cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03434
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186280_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34041
chr1_95237888_G_T_b38	GTEx eQTL 2025	1.0	6.21848
LB771HNC	DepMap CRISPR Gene Dependency	1.0	3.07019
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Quebec platelet disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RC-74-NK42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232791
PMC9046280-41467_2022_29963_MOESM8_ESM.xlsx-Supplementary_Fig_4B-Genes_annotated_to_enhancers_bound_by_ASCL1_ChIP_and_lost_expression_in_42D_K_D_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-468-ENSG00000143033_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	8.59336
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8258
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-41-TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5136
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207059
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04376
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43217
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.8479
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17349
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11408861-mmc2.pdf-11-TFCP2_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49488
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-19-MTF2_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.19598
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.2938
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-58-PW17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239179
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49043
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2851
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301504
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33169
J-774 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284311
A498_KIDNEY	CCLE Cell Line Proteomics	1.0	2.28387
BCX 1470	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU685_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	2.49495
AC-85-MR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228573
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3857
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6275
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207914_2_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AR-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0686
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.523
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264526
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3967
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
VMCUB1	DepMap CRISPR Gene Dependency	1.0	2.06979
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149075_2_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156166
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05841
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1209
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
chr1_95133037_A_C_b38	GTEx eQTL 2025	1.0	1.01252
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	3.78263
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18031
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353215
42MGBA	DepMap CRISPR Gene Dependency	1.0	2.17772
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10921
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63859
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21143
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183143
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5489
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-87-EI21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214705
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0639
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45567
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5384
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11649
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6188
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_10_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11245
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237791
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9474
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438884
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CIAPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00344
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx SmallIntestine 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.10097
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7121
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18645
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20978
HNRNPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5496
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01813
Verbal declarative memory	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
Prucalopride	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
PMC11091074-41419_2024_6684_MOESM1_ESM.pdf-4-ZNF493_ZNF493	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143_BREAST	CCLE Cell Line Proteomics	1.0	3.89262
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34228
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6928
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.80101
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212775
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE157594_3_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017134
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28359
CAL78	DepMap CRISPR Gene Dependency	1.0	2.12849
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1106
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304971
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null