association	dataset	threshold value	standardized value
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26098
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23209
FOS	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02925
Perturb_2457_Mut_SRPK2_SRP254546	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.83727
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
OC-71-BZ81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233937
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32679
BRD-K57026098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43475
BRD-K37479727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21725
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80773
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5814
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958313
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41082
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12659
glycocholic acid-2454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15973
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39902
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64404450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06302
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.64213
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1152
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443222
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08587
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10949
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ribonucleoprotein complex biogenesis	GO Biological Process Annotations 2025	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.823
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862287
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74983
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23801
BRD-K62182950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55053
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3C8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699453
gliclazide-2870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.61227
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00450408
GSE110708_0_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12821
palmatine-4957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67626198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12794
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17414
Perturb_5156_KD_Mta2_SRP046299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.54393
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.22885
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ursodeoxycholic acid-3105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57801
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54015
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00058
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07984
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93977
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865352
BRD-K75076471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20975
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43754
5707885-6390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865316
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31414
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76271
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247422
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40635
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90035
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1388_KO_Tet1/3_ERP010627	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.3892
tanespimycin-6966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pioglitazone-7088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97265
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08587
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01389
BRD-K46065636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23366
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
metergoline-1606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cefaclor-2483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93135
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43181
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235603
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.475
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76253
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43107
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12974_KO_IGF2BP2_SRP365416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.77164
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	2.88291
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422976
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56771
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95342
SU-DHL-10	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.73186
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.10405
nucleolus	GO Cellular Component Annotations 2025	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
metamizole sodium-6030	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UIMC1	Pathway Commons Protein-Protein Interactions	1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50605
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02711
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29243
BRD-K02517738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17946
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
u698	HPA Cell Line Gene Expression Profiles	1.0	1.19821
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29875
fulvestrant-6965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_16000_KO_TP53_SRP261893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57902040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09662
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41789
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02021
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03603
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52212
calycanthine-6221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2555
IALM_LUNG	CCLE Cell Line Proteomics	1.0	2.58969
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.55779
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6127
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849509
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bisacodyl-2435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10494344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03638
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73112
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0012
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CLPP_KO_GSE40207_380_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33858
nuclear lumen	GO Cellular Component Annotations 2023	1.0	null
BT-474	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.21324
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86873
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
EP300_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51144
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03493
nucleolus	GO Cellular Component Annotations 2015	1.0	null
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43449
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3207
ZXDC_KD_GDS5070_504_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM160	Pathway Commons Protein-Protein Interactions	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1399
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27445
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6264
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24475
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.48516
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28733
cinnarizine-1558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943713
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11542
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83681
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26918
BRCA1	ENCODE Transcription Factor Targets	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.0791
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K31059261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30105
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830707
hsa-miR-4801	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6793
BCL11A	ENCODE Transcription Factor Targets	1.0	null
ASCC3	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26167
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91477
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.842525
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41584
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78015
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912249
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32372
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953934
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5284
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XG-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wortmannin-1184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08587
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5485
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56359
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03311
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33722
hsa-miR-3139	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
chr4_163542377_A_G_b38	GTEx eQTL 2025	1.0	1.2083
chloropyramine-3350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K47504528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16174
TE9	CCLE Cell Line Gene CNV Profiles	1.0	2.16071
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57792
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256722
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
speech-language disorder-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87075
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365845
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48645
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.85057
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4969
PMC7817097-abb9149_Table_S2.xlsx-293T-TET2-FLAG-Table_S2_Mass_spectrometry_results_for_endogenous_SMCHD1-FLAG_in_ES_cells_and_TET2-FLAG_in_293T_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9592
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.0524
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT55	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.40613
zardaverine-2926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.12434
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981391
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2822
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883243
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82554
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20112
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946898
TEAD4	ENCODE Transcription Factor Targets	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FYCO1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.48052
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.92692
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GMNN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00431223
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36841
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48358706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20592
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K57357304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86843
guanadrel-2575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38649
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribosome biogenesis	GO Biological Process Annotations 2025	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888232
levomepromazine-7399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A35931254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5468
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33314
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51904
acetylsalicylic acid-1629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49287
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39315
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A50E-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
angular gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0765
TNFSF13B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00733826
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0298
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7933
BRD-K45282594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07834
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56711030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18849
ribosomal large subunit biogenesis	GO Biological Process Annotations 2025	1.0	null
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45874
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879077
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11071_KO_Slc10a1_SRP174097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.14283
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pentamidine-4396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K82397896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15791
tomatidine-1754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19134
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19505
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
famprofazone-4309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
colorectal cancer cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.54915
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862287
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04816
BRD-K42582718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95533
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83122599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0611
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17963
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05436
SP4	ENCODE Transcription Factor Targets	1.0	null
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22122
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913856
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7303
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-85-ND09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219845
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09896
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC5840266-41598_2018_22384_MOESM13_ESM.xlsx-UBR7_KD_significant-Unnamed_23_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24858
Superior colliculus, optic layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32767
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17015
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38688
Perturb_2595_KD_SMURF1_SRP115428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-664-4737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533975
BRD-K48412518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76898
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39095
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845909
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852069
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77899
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933118
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cefoperazone-1627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24494475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49508
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1309
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844695
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824749
Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15605
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41413
MAZ	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32293
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
IL13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644623
BRD-K44403120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16101
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19832
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20204
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.69273
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02381
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06718
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891339
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44345
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FTC-133	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.74072
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2885
SRM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623459
CCT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15974
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67261586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09693
nimesulide-1428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56276074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08909
ALDH7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91467
ED-05-KX67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212505
pempidine-2172	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
PMC10189495-mmc10.xlsx-TCF4_wk1-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05632
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K91511557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41411
Thyroid	GTEx Tissue Gene Expression Profiles 2023	1.0	5.62671
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59566
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4357
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86688
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39824
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25202
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04711
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995299
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.388661
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828864
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873261
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
19061838-TableS7	GeneSigDB Published Gene Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78965436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84346
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39963
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28561
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932066
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18371
lincomycin-5992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56427
BRD-K61020385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52043
MYCN	ChEA Transcription Factor Targets	1.0	null
BRD-K70361311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00919
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38949
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.962246
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27805
PMC12816669-41698_2025_1236_MOESM1_ESM.pdf-863-ZNF830_ZNF830	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56079
LPCAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546876
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14987
UTP18	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.855832
neomycin-7221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ouabain-6680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825951
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.46441
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31488
9420_TUBB_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.700136
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57331
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.67584
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69864
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19471
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1623	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54252
geldanamycin-864	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19225
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	122.15
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18766
BRD-K63163033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04674
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Childhood brain stem neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29332
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90812
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22534934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46883
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33744
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228405
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29005
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0545
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16929
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51769
oxaprozin-863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49985
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15227
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0246
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25872
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81472
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-56-IR20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259874
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30884
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K09250623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41253
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A633-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.62724
TUBA1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00700568
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0356
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02465
JAZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0075257
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239072
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90984
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63031
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19915
NFF	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.76963
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1894
PAX5	ENCODE Transcription Factor Targets	1.0	null
DDX24	Pathway Commons Protein-Protein Interactions	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33860558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22121
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27981
estradiol-5955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SR-95639A-3272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10655
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11216188-peerj-12-17616-s013.pdf-88-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88908
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897148
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992854
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60312
Hyperplasia	CTD Gene-Disease Associations	1.0	1.44599
MAX	ENCODE Transcription Factor Targets	1.0	null
IRAK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562639
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48528
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18555
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04397
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05796
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00413413
SNU283	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71356
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.550804
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56958
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
preribosome binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0837
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82675
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17975
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50078
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
naltrexone-2047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
TAF1	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04516
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
piromidic acid-3335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.252684
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845082
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	3.2011
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HSF1_KD_GDS1733_753_human_HeLa cells - 4 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
tretinoin-390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0832
SULT2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503925
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Small Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
BRD-K57643011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32023
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cefixime-4390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23022
CRCGN015_HEPG2_48H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96322
hsa-miR-4731-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.669633
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268326
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2653
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32379
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1346
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01803
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small-subunit processome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.325
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	1.92241
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53046
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894609
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.475
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-28-GJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272406
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843984
BRD-K31721388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12014
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1867
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0331
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tanespimycin-6978	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91798
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04629
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.32637
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2485
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23529
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36493118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69186
naphazoline-1966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996031
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45621617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2458
pentamidine-2834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56285
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62686
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0626-SM-3NMD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889244
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27741
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867687
MAP1LC3B	Hub Proteins Protein-Protein Interactions	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSC735380	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
GSE180468_2_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937354
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21444
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841233
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978605
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835204
BRD-K96377358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06768
Childhood brain stem glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31395
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983286
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86634
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9272
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K60389305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3342
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17933
Lung adenocarcinoma_LUAD_TCGA-78-7145-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05465626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18534
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0113
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55816
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4409
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464054
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37534
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28504
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00698
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02067
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70408
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35004
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRINP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38988
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12262
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44777
phentolamine-1138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
citalopram-4555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.545
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03823
flumequine-5104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01572
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trifluridine-7176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
naphazoline-1466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-ddORF6_96Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76961
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25137
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30214
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31728
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K23870105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36513
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62916
GSE81193_0_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45629
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.81983
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06674
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950108
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298233
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13207
Nuclear RNA export factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.354
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884924
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56463
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54578
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0644
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30352
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A89441445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09386
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68856
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08333
HCC1500	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.59781
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Box H/ACA snoRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43192646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05886
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72185
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
terconazole-2484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36481
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etamivan-2879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36945
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RB_P107_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.0288
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28997
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.064761
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.57953
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2685
BRD-K69808609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12768
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CADO-ES1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11763
fenspiride-1422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16037
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10892
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.08055
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912932
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78138
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.581547
fulvestrant-7495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chlorphenesin-1432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.34405
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26564
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430777
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50468
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14192
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.035544
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9742
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11844807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81311
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38386
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24314
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56839
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66724
6-benzylaminopurine-4748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4239
CRCGN014_HEPG2_3H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59504
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72239
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42908
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09657
trifluoperazine-1165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844352
COLO829_SKIN	CCLE Cell Line Proteomics	1.0	14.7075
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3749
lovastatin-2494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20991
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49992
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP188	Pathway Commons Protein-Protein Interactions	1.0	null
XPO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00859688
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19915
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.551
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A31576716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.303
paclitaxel-2043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_176_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.46089
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27364
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90544
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976472
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USP9X	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571547
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.899731
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933418
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35573
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00743566
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06767
SK-PN-DW	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03406
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87071
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_11_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K70380532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09622
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASSF5	Pathway Commons Protein-Protein Interactions	1.0	null
CASS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620059
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03622
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ED-43-XF39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23577
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51435
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.995783
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29825
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6966
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2368
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15439
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35981
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.62963
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
beta-escin-6050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.15843
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73274
BRD-K96969336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58934
T84	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.21746
GSE180468_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09579
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1655
BRD-K77119472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12632
naftifine-2974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K73357010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08551
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45622
CURI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
BB-62-MS83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239581
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69745
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945918
Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1B	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11683
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0853
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3942
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.15258
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10474
trichostatin A-6886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FA-92-JL46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239218
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50504
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28124
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921022
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06698399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34608
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95475
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08821
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86634
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00388237
etanidazole-6072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.702813
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47756270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00964
Perturb_13439_KD_Myb_SRP119047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17165
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27152
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.12713
thioproperazine-1390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04863
BRD-K31204557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63729
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28058
protein binding	GO Molecular Function Annotations 2015	1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07399
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30378
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9222
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962224
acepromazine-2769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02437
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0227
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
dihydroergocristine-7034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU449	CCLE Cell Line Gene Expression Profiles	-1.0	-2.45311
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43261169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02842
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08984
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66299
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44648112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36042
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SB-202190-7054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABI3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644033
BRD-K52532740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31758
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114992,GSE114993_1_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830547
PSMB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00623953
GLDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15267
BRD-K73227372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29199
proscillaridin-2920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04192
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848637
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845827
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12012
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NES-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03553
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.16634
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20461
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20929
BRD-K57575504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03513
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
azlocillin-5788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0319
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36793
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3686	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29204
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63808
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.041732
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17708
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21045
MEC1	CCLE Cell Line Gene Expression Profiles	1.0	2.45027
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17553_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
EF-99-HJ48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289431
HUH28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62007
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A34492468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19095
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.52743
IFNA14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00384486
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48389518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10396
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15205
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08258
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8593586-mmc2.xlsx-LIN28A_interactome-Unnamed_1_LIN28A	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.252
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16541
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39561
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243779
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.89237
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
dipivefrine-1752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28906
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52906
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46413
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27534
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932674
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Las1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
halcinonide-6040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51707293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44505
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937354
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19644
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57650037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0523
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90928
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40287
BRD-K62852603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78248
G6PC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546514
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03777
BRD-K64132098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02557
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isopropamide iodide-3461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CB-32-EI69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26403
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.48
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	223.389
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32137
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840038
TRIM28	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68398
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901104
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC12260418-pnas.2425984122.sd02.xlsx-TEAD1_6fraction_test_result-Unnamed_3_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
OUMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58109
BRD-K60886324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13795
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.69615
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05164
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64174
NCIH441	CCLE Cell Line Gene CNV Profiles	1.0	1.49746
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0397
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38522
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931138
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.118806
BRD-K43992442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39106
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99656
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12651
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13755
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894835
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6966
MCC	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K24226959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98404
PMC8160578-JCB_202009147_TableS4.xlsx-MYBL2_targets-Genes_n_532_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
PIP4K2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00666953
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78969
(-)-MK-801-5003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9596
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824609
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906479
CCNT2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90139
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11305
BRD-K67042874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29895
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45757
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910139
Perturb_1176_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52358
CEBPD	ENCODE Transcription Factor Targets	1.0	null
geldanamycin-6946	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853559
KMS18	CCLE Cell Line Gene Expression Profiles	1.0	1.39711
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57354
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE114992,GSE114993_8_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4538_KO_Mtf2_SRP103933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.78293
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37785
co-dergocrine mesilate-2136	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9012
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOL6	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922429
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15814
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01618
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A64153357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05728
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37679
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900174
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83171
preribosome, small subunit precursor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.998
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16617
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75693
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.51528
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49423
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05787
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850227
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09187
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
finasteride-2206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01161
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22662
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.52933
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGROV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28523
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63623
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26277
ETS1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
acetylsalicylsalicylic acid-6778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92806245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22915
Perturb_2747_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
genistein-1073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.59757
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37942
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59409
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51192
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72215
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01949
laudanosine-2890	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22827
CRCGN017_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14321
nicergoline-2220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metformin-1816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
15-delta prostaglandin J2-1656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.28953
ZEB1	ENCODE Transcription Factor Targets	1.0	null
EGFR_drugactivation_19_GDS2146	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.02681
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6709
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6098
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15996
pseudopelletierine-1774	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926962
BRD-K82637883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24338
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09864
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33084
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04304
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36822
GSE134375_4_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46949676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06938
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1416
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12704
BRD-K42968343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13376
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29219
Acute Myeloid Leukemia_LAML_TCGA-AB-2853-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850619
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78331
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893844
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.852
BRD-K44004565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2824
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.831719
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24863
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86019
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874454
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73343
BRD-K68605096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25045
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_5_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48035513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26627
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3985
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74041
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25813
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22865
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45711
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42223
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0847
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89594
BRD-K99404845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83532
EBF1	ENCODE Transcription Factor Targets	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28379
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18264
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50259
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61691
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.915823
sulfamethoxypyridazine-4733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14884
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4565
ASGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536477
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76104
Perturb_3772_KD_BEGAIN_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K80381603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7379
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09286
corbadrine-2710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Eukaryotic translation initiation factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.226
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.91179
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
rosiglitazone-1071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12704
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHU-011	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.02659
NMuMg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_0_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
5248896-838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0293
raubasine-2898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66977
BRD-K64567246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40945
BRD-K88977610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68282
PMC5998130-41467_2018_4619_MOESM7_ESM.xlsx-specificity_NCOA3-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941971
Prestwick-685-3683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27563
MB-32-LQ97_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240737
BRD-K95121261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68641
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987346
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.826984
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2485
BRD-K37544873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22961
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57489406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64222
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67D-01A-31R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3875
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89249
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-34-TG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214154
GSE135350_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32195266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38079
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85957
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.891897
SIN3B	ChEA Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60524
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.83141
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18629365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19497
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19851
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05068
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06226
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07805
ELK4	ENCODE Transcription Factor Targets	1.0	null
HCT-15	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.55237
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35302
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250504
BRD-K60719499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21166
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22895
ZXDC1_KD_GSE45417_686_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61502
Perturb_14662_KO_Ogt_SRP198294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925075
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23035
16479545-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88847
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.970418
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921768
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.68094
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17279
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41584
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85484
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32000549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03834
A549_Ellagic acid_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144862
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1416
DU145	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.86029
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73535
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028064
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22694513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26706
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29495
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar Disorder_frontal cortex_GSE5388	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.62495
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34406
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15656
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96454
BRD-K42849858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20098
Left middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_65_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.0269
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21865
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09021
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3148
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53336
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847611
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19395
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03215
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K75746738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01054
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
prilocaine-4749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleolus	GO Cellular Component Annotations 2023	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86634
BRD-K50053371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24262
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50972
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6325
todralazine-1841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
1,4-chrysenequinone-7139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.00722
GBAS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859445
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80746
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83456
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13757
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2953
BRD-K32269272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16355
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67477
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21781
BRD-K11506071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01809
sulfasalazine-2882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UACC-893	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.46443
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242585
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06169
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857622
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41158
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24405
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4742
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22429
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839059
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skimmianine-6242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17152303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26817
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91593159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63622
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.56969
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1_BRD9-Nearest_Ensembl_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43622
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K71141540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28407
Lung adenocarcinoma_LUAD_TCGA-38-4629-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470855
BRD-K10358320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9678
MYC	ENCODE Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08946
Perturb_2746_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12705
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842864
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6898
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858715
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20605
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6241
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43815
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857841
OUMS23	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72905
TEK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053553
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.037483
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03247
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30157
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3329
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES7	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.88631
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40791
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346647
JEKO-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99156
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00750938
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75216
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08065
18535662-TableS2d	GeneSigDB Published Gene Signatures	1.0	null
PMC10534007-Table_2.xlsx-S2_overlap_MSC_down_B_V-395_common_elements_in_VM-CUB1_MSC_down_and_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42225
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37451
SNU182	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64916
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
amrinone-3465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fluticasone-2928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978748
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899804
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64821
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.89041
bergenin-3467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PRKCI	Pathway Commons Protein-Protein Interactions	1.0	null
scriptaid-6896	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30962012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2346
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48737
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.023644
NCI H23	BioGPS Cell Line Gene Expression Profiles	1.0	0.86208
BRD-K73494324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22242
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03847
90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.906
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04737
BRD-K41306114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80673
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17034
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87458
ribonucleoprotein complex biogenesis	GO Biological Process Annotations 2023	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55449
fipexide-1560	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54081441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75825
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60606
NCI-H2347	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.98974
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19779
BRD-K42814713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72101
meclozine-5607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49418
rimexolone-5092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
appendix	HPA Tissue Gene Expression Profiles	1.0	1.2028
DHX40	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137144_4_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-6910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amikacin-1618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65187
Perturb_10190_KD_AES_SRP073721	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48974
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26748243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37196
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929495
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-0.854409
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04622
Perturb_1182_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.1645
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17056
scopoletin-3131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
FOXA1	ENCODE Transcription Factor Targets	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.08868
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922512
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12704
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hexestrol-6252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K46095779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7845
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90852
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0518
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.16954
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34979
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03247
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56711
BRD-K90349877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00172
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21079
DL-PPMP-1121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40996
selegiline-2826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883912
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5792454-mmc2.xlsx-Table_S5-Table_S5_Genes_up_or_down_regulated_in_murine_Hoxa9_IRX3_leukemias_versus_Hoxa9_MTV_leukemias_Gene_Ontology_annotations_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR4	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11007
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12848
phenyl-aminosalicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03379
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17947
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC2A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055959
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14804
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20162
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48615
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03227
CRCGN016_MCF10A.TP53.M_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0211
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12964
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880131
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470953
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90978
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KU1919_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.34745
NCIH1385	CCLE Cell Line Gene Expression Profiles	-1.0	-3.98953
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87264606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49649
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39751
praziquantel-1572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cisplatin_dictyostelium discoideum_gpl5382_gse8287	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05064
epirizole-5995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5989
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11056
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clenbuterol-1613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.91439
trichostatin A-3114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06295
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31868
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829391
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33968
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19557
midecamycin-1943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0701
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04134
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KO-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49102
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6594
FMR1_KD_GDS4759_333_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24352
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934566
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23275
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868598
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	256.514
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28386
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1187	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55362
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K27945483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08484
Integral component of peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.777
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37679
BRD-K03901181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11519
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
noretynodrel-1860	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46978
Prestwick-674-4738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51399
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26655
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.769
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81387
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.28257
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229228
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869304
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1902
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NU-DUL-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.79514
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28079
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79159
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08759
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61304
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anabasine-6774	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vidarabine-3445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1553
HUPT3_PANCREAS	CCLE Cell Line Proteomics	1.0	2.19803
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9498
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19335
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08991
BRD-K59606563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54933
BRD-K44086628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98939
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
BRD-K37989903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95666
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55329
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13269
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.43252
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68087668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94731
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05081
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6433-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP1LC3A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86835
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867296
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65008
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849899
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859028
STK3	Pathway Commons Protein-Protein Interactions	1.0	null
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49371
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94635
E2F4	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13318
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886348
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10201
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20252
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15213
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00813
alimemazine-3478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03704
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90429
HT1080_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	2.71429
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981461
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922429
minaprine-1968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55738
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866758
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54925224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12815
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1787
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58757
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_1900_KO_Nr1h3/Nr1h2_SRP043965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.97358
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03387
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08364
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03922
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.844163
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3962
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAP1LC3B	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.357
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67546
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04624
PIGL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470278
BRD-K93260425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59723
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98441254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12293
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93482
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61786
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00519
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34278
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79568
nuclear lumen	GO Cellular Component Annotations 2025	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4683	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964319
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IKZF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_12324_KD_PHF20L1_SRP188318	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.707
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78606
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20898
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
etamivan-7260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tolazoline-1500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53746
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00632
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.50958
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939723
BRD-A07407288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24184
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969542
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34654
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29325
NTRK3_drugactivation_67_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81484
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83375
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12175
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18298
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87080232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39932
BRD-K95479169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91643
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08489
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69038251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73638
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909425
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9709
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41584
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
GSE223008_11_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03506285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07655
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27829
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47747
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03637
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02522
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.02821
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97328
RFX5	ENCODE Transcription Factor Targets	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11535
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46484
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71672
Cardiomyopathy, Dilated_Myocardial tissue_GSE3586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66859
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Nucleoli	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2705
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15053
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07689
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981789
betonicine-6063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3802
KB-72-ID36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272712
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNB75	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.862894
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K21595913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53475
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-888	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0913
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1148
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.6527
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7100-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20368781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33794
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49497
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18371
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22078
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14187
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863288
molsidomine-2862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58456
BRD-K56107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07236
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186483_6_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24271
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliary neurotrophic factor receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88164
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13145
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.57125
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14124
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30288
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10289
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55446
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17683608-TableS5	GeneSigDB Published Gene Signatures	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21276
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78755361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96059
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72407
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01994
KYSE140	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21115
NCI-H2803	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.28445
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39913853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04459
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64028
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heptaminol-7313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65023
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEK 293T	BioGPS Cell Line Gene Expression Profiles	1.0	1.43312
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959804
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20885
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33948
LY9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512256
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23145
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06411
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16029
fulvestrant-367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23234
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protoveratrine A-2800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.95735
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36071
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49724
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69437108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2143
AD-40-WB93_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216893
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7948
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20845
BRD-K77354700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41411
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7836-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37516
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11651
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914783
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868325
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897898
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19258
BRD-K72484719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36778
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20697
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10098
lobelanidine-2897	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236656
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5088
amitriptyline-1865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.25725
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54373
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13161
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3386
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.40214
SK-MEL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.87531
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9854
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K27864398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39456
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05384
chr4_163519591_T_A_b38	GTEx eQTL 2025	1.0	5.20143
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00608
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mewo	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.26769
organelle part	GO Cellular Component Annotations 2015	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
biotin-3289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03543
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02193
bretylium tosilate-6674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841403
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09485
Lung adenocarcinoma_LUAD_TCGA-69-7760-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74651253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30787
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831257
CSMD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635183
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82165
meticrane-1792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDX1	JASPAR Predicted Transcription Factor Targets	1.0	null
0198306-0000-7064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
15-delta prostaglandin J2-1231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18129
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30165
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911273
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nuclear part	LOCATE Curated Protein Localization Annotations	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58113140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10687
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4293	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
galantamine-4772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74677971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22569
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965828
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Preribosome	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13492
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237113
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01213
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BIRC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506561
POU5F1	ChEA Transcription Factor Targets	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79928
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22259
CAOV4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95556
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMBR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00766771
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18642
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77854
trazodone-7452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16345
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50363
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
F0447-0125-6424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35429
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17806
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954517
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926006
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45328
HCC1395	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.02704
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52211
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903345
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0673
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.965695
BRD-K96768352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3741
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04336
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33212
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03319
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.052
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
nucleus	GO Cellular Component Annotations 2025	1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25364
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65346
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02428
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.845
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937354
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2466
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
brompheniramine-3271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
(-)-catechin-1101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.19451
MAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09317
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24281
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57601
HeLa cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.856885
ribosomal large subunit biogenesis	GO Biological Process Annotations 2023	1.0	null
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34601
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.189
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87428
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1898
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.118806
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3574
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.70326
PMC12830621-41467_2025_67611_MOESM11_ESM.xlsx-Sheet1-Suppl_Data-9_Common_differentially_up-regulated_genes_in_high_vs_low_Mecom_MECOM_mouse_KME_AML_cells_and_human_AML_from_4_public_databases_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
HLF	CCLE Cell Line Gene Expression Profiles	1.0	1.79761
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.515
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68358
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04224
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873504
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42424
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998201
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62402
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04739
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13644
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44035
MCC	Pathway Commons Protein-Protein Interactions	1.0	null
CLPP_KO_GSE40207_396_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
wortmannin-869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04336
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05773
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93788
EC-GI-10	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.90739
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64208
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
canrenoic acid-2065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
propafenone-2871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34683
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
mianserin-2231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
etofenamate-2907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMT2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518282
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976909
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956205
MRPL45	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02436
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
articaine-3138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fulvestrant-1663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulate gyrus, frontal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.956681
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01808
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1677
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.465
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90139
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27121
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35302
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13904
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3025
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07822
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21638
HS936T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49101
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_177_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79485
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYLK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588603
salbutamol-7376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67123
BRD-K35788497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20708
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QC-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23852
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3541
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19768
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16964
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19752
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-116-ESX1_ESX1	Rummagene Transcription Factor Associations 2026	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.926715
BRD-K59445060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82384
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37573
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990269
sirolimus-1080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16789
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.49508
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
BRD-K37269981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95461
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.947135
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07321
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06218
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26446
gabexate-4804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27323347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1725
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830063
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9999
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27449
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35595
hsa-miR-127-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03818
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253693
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05231
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.968554
16424041-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9647
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956151
KDM5B	ChEA Transcription Factor Targets	1.0	null
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14824
DANG	CCLE Cell Line Gene Expression Profiles	1.0	2.17486
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30948
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853163
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34216
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81715
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1973
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6682
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-0940-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0506
tanespimycin-1166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TIE1_knockdown_107_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.58133
methyldopa-3234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BTNL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00724809
CEBPB_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00005
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00794
GCSAML	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523167
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993247
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251806
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77493
GTEX-XXEK-1226-SM-4BRUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910047
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1_BRD9-Gene_Name_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	187.181
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112760,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905702
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28565
Nuclear pore linkers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827139
BRD-K49745983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01108
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54856
BRD-K20745677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43307
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1354
Inflammation	CTD Gene-Disease Associations	1.0	1.52489
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8519
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.69465
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02249
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RQC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.288
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30214
propidium iodide-6104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09735
BRD-K57821544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23366
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
monorden-5952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXD4L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.005019
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28555
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5499-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01213
BRD-K51490423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08485
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3088
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05831
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75502
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36581
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12704
BRD-K30121969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00991
Prestwick-1084-6125	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-2526-SM-3MJGT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983366
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960919
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057217
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857859
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4581
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08932
PMC12260418-pnas.2425984122.sd01.xlsx-TEAD4_6fraction_test_result-Unnamed_3_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05806
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45539
colliculus superior	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00981
HDQP1_BREAST	CCLE Cell Line Proteomics	1.0	4.56569
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01972
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20107
bisacodyl-5677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.80628
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21539
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
tanespimycin-5586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1385
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TD-01A-51R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03682
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2511
alvespimycin-1154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857707
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892022
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4664
hsa-miR-891b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K32485819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25636
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62369
BRD-K92239253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01795
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WW-01A-22R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18476
BRD-K27726273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0461
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10142
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25195
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10914
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trichostatin A-1535	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33752
BRD-K85821470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38665
Perturb_10198_KD_FIP1L1_SRP251753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428064
5869_NUDT21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.598217
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81794
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56913
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15554
BRD-K52254237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30232
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26211
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20364
POFUT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604056
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deptropine-5118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77237686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01151
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840902
TAF7	ENCODE Transcription Factor Targets	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
repaglinide-3558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57818
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.12434
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-KDM5B-Unnamed_3_KDM5B	Rummagene Transcription Factor Associations 2026	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33611
GSE151782_4_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.91798
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06735
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.475
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2879
hsa-miR-4633-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954718
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14829
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
acetazolamide-1850	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16068
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908412
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08587
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pentolonium-2305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_67_KO_Rnf114_SRP301146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06524
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38248167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11302
spiradoline-3818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clofilium tosylate-6830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5318969-bjc2016426x3.xlsx-Sheet1-Supplementary_Table_S2_55_additional_PAX8-interacting_genes_from_the_Ingenuity_Target_Explorer_PAX8	Rummagene Transcription Factor Associations 2026	1.0	null
3-nitropropionic acid-6407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996597
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51148
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93267
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
Ralfinamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42275
GSE223008_9_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58538
tropine-6264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974175
CRCGN015_HEPG2_48H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87409
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883459
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-708	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21246
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87902
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52568
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diprophylline-1853	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.21537
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50056
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6541
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03288
BRD-K00793226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0235
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8487
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4SV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828408
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K92312193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09145
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06905
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24899
levamisole-1410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39495
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32079
BRD-K61451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61946
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7752
BRD-K68002543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34706
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.966391
BRD-K35491869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11031
CRCGN017_MCF10A.TP53.M_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24475
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20972
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4176
TP63	ChEA Transcription Factor Targets	1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ricinine-2505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82201
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52642
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ChEA Transcription Factor Targets	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-2.80222
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37652
BRD-K52075209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08819
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93502
BRD-K84606053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81382
GSE110708_2_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03194507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06978
Lung adenocarcinoma_LUAD_TCGA-64-1680-01A-02R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18823
STK4	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60446
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13525
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0867
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09787
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15952
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957774
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165334_3_v_1_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86857
monensin-1105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028047
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.59877
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.04292
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56732
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42258
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4196
639V	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67339
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31472
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17526
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05549
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0293
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	1.52553
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00173
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MSI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056877
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7035
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845633
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17917_KO_Shank2_SRP314506	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19699
atropine oxide-1370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67272
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28521
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31026
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.092
daudi	HPA Cell Line Gene Expression Profiles	1.0	0.923286
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
liver	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.30586
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8514
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ouabain-5026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24433
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.38467
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484595
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38726
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.835434
cyclizine-2880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932844
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73261251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66427
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15663
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FTC238	CCLE Cell Line Gene Expression Profiles	1.0	1.59683
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901446
NUFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
RRM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501863
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951449
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78958
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12742
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0643
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0264
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20422
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37693
CA-31-EV03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26734
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06915
BRD-K23204256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60161
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16973
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06767
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6851
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28212
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2759-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855801
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62888534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10873
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49026
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17532
tretinoin-1152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K35799753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2976
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethambutol-1481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4435
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-4710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.59026
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18627
BRD-K56778317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01051
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15969
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15438
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46782
BRD-K91799761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69377
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983601
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01537
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936887
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73589
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62717
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29043
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.855222
appendix	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44614
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3638
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.44198
lymecycline-2953	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998723
hsa-miR-28-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE98579_0_v_1_tfam_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01681
tretinoin_mus musculus_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
scopolamine N-oxide-1415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30399
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4	ENCODE Transcription Factor Targets	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diffuse midline glioma, H3 K27M-mutant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
hel	HPA Cell Line Gene Expression Profiles	1.0	2.06288
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21998
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824233
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32014
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71165
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80733946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44475
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48086
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842472
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40046
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
helveticoside-3851	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10154
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04882
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVOL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557116
epivincamine-6838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20023
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12543
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849953
chr4_163511210_T_C_b38	GTEx eQTL 2025	1.0	7.06859
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15894
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Histone mutated tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48144
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23314
BRD-K62621376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00739
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991729
PMC6336197-NIHMS1515792-supplement-Table_S1.xlsx-Differentially_exp_d_genes-Supplemental_Table_S1_ICGS_identified_2_368_genes_that_are_differentially_expressed_between_CMP_MEP_MKP_and_ERP_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11886_KO_Akap1_SRP316337	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33301
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844657
clemizole-2301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210228
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42805
fluphenazine-2697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16111
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
piP-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.13012
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03886
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2818	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.10384
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62358
myosmine-4759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2105
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.844395
GSE239844_8_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3804
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871764
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-01-ET52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233336
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963616
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122101,GSE122103_0_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_7_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.7785
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06398
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10559
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00167
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
naproxen-1869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01106
oxymetazoline-1431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93831
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54123736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85004
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	1.0	2.36641
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7476
GSE124410_2_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
BRD-K80921954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6838
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19518
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03756
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17181
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7919
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25138450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11389
Lung squamous cell carcinoma_LUSC_TCGA-18-3415-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51264
EOL1	CCLE Cell Line Gene Expression Profiles	1.0	1.57517
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05623
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85937
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.69612
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11794
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90665
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01763
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21019
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BL6644 (EPS15L1)	NURSA Protein Complexes	1.0	null
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0633
BRD-K97624648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15469
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10217
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79383
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49207
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40056
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62547690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89723
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.44472
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCILY10	CCLE Cell Line Gene CNV Profiles	1.0	1.47495
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02519
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67813189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70381
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33926
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55115
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
levamisole-7450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00545
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860419
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39971
BRD-K00950228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62906
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917487
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17219
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6624
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.87349
BRD-K21771537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42558
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878986
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3663
fulvestrant-1146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832674
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978605
ATXN2L	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17917
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Small cell lung carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.26205
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23884
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
picotamide-6787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11318
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43685
BRD-K69780027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06211
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15914
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35692
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86634
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1359	CCLE Cell Line Gene Expression Profiles	1.0	1.52887
SGK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00390966
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2935	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69475
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38123
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
PF-00562151-00-5959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alverine-1426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
monobenzone-3054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.42549
CCL4L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515036
GSE186483_1_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08525
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
indometacin-7409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dicycloverine-1983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viomycin-7036	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25185
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K38557431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98792
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38978
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43007
D-392MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.65212
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891866
BRD-K18783332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08777
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09775
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12942_KO_YBX1_SRP321707	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.70658
CYBA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507857
BRD-K96384208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45996
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.016
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ajmaline-2899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37267
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.314
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.47792
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.07199
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
alpha-estradiol-6930	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20891
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642852
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59795
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.38623
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1297
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954769
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79972
BRD-K71737889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90484
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35444
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ALKBH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34428
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2191
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914919
ACE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550781
BRD-K37356599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09467
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20841
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59125
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18493
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03338
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08775
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90248
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14923
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00381531
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892115
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K43053725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00561
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53772256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91749
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42398
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cyanocobalamin-4395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31997
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8786
BRD-K02987495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71232
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06254
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.697
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Ktp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992519
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72415
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14287
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08939
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12517
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
EFM-19	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.49865
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18855
NRF1	ENCODE Transcription Factor Targets	1.0	null
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung cancer	GWASdb SNP-Disease Associations	1.0	0.512886
Perturb_17554_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.33473
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29455
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19826
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37889
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10914
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16999
GNG11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511764
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fluocinonide-3414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08501
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8828
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65332
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826246
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23926
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19228
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A14098586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5236
PIP5K1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617761
BRD-K31093279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30675
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01998
Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
etofylline-1409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trifluoperazine-5442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16618
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70738
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	2.50763
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.47244
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23048
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67289
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39286
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.9392
IFRD2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-366-ZNF618_ZNF618	Rummagene Transcription Factor Associations 2026	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45092891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07783
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228627
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25092
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836691
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5531
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.987479
BRD-K88670720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69363
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79954583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68988
NUP62	Pathway Commons Protein-Protein Interactions	1.0	null
clidinium bromide-3476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74475
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.951991
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
trapidil-3136	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50392
HLE	CCLE Cell Line Gene Expression Profiles	1.0	2.00636
JUN	ENCODE Transcription Factor Targets	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831576
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89888
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30825
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21951
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6816
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15806
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39566424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12515
BRD-A03764094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11929
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58456
BRD-K18864235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1495
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nalidixic acid-7367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06552
BRD-K46293468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34947
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824198
CRCGN017_MCF10A.WT.HP_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9926
helveticoside-3945	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00817
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232791
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9467
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217246
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YTHDF1	Pathway Commons Protein-Protein Interactions	1.0	null
16424041-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10218
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13448
RRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00816969
prochlorperazine-1156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901234
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
tetracaine-7473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76431854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99057
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27198
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831256
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3032
E2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25794
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08331
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6451017-41598_2019_42107_MOESM11_ESM.xlsx-all_MYCN_as_effector_lincRNAs-mRNA_genes_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.58
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trimethadione-2486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
8963_TMA16_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.804689
Pilomyxoid astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
hydrochlorothiazide-1906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.539493
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98703
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03919
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7558
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20168
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49099
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67242
COQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35163
PLTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537027
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11118
pirenzepine-2234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.75855
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74091
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4984
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874225
BRD-K68574010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0585
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22106
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30702
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04436
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrastine hydrochloride-6011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.2648
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1134
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41139
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37626
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878341
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39078753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10026
sirolimus-1162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.83535
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41241300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90945
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.092877
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51247
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15852
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78007
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37575
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05644
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23035
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12545
BRD-K07020302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96589
BRD-K79048835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01292
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02937
Perturb_1594_KO_Rpl23a_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.46024
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05508
Lung squamous cell carcinoma_LUSC_TCGA-52-7812-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17176016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41986
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24729
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2191
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Trolox C-2883	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41514
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951003
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
TEAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497434
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894773
dipyridamole-5617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62971
hsa-miR-3689e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8901
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220635
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11495
BRD-K05185748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00891
RELT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533238
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9179
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954817
IPMK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465206
NME7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461242
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
zalcitabine-2932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KGN	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.66162
PMC11814113-41467_2024_55326_MOESM3_ESM.xlsx-BP_Dorsalgia_GTExQTL_loci_MR-Unnamed_12_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09633
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50111
pipenzolate bromide-4484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72647169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02344
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72385
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.984092
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8607
BRD-K20847739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00776
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.93045
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03604
BRD-K99048639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5807
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36486
fulvestrant-1076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114992,GSE114993_1_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8877
BRD-K08730634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67383
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00071
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27624
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.51219
BRD-K13074426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44768
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.35855
GSE200159_1_v_0_setd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0867
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19657
CLNS1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87324
REST	ENCODE Transcription Factor Targets	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33995
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23966
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74976
Ribonuclease MRP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
PMC10199266-mmc2.xlsx-RUNX1-DEGs-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-691-2813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20034
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10048
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4021
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dactinomycin_mus musculus_gpl1261_wild type_gds2456	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1713
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13393
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35493
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836733
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.77446
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885934
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94574
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15887
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29803
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72661
MOLM-13	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.43481
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892908
BRD-K22633587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29968
BRD-K47754225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36155
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35863
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19794
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00292
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.08396
KCNJ6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613295
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33635
pargyline-7016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K86630280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47168
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
valproic acid-1020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96618
sparteine-4391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3529
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
BRD-K52424224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39245
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A5ND-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64904523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68781
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05143
NCI-H322M	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.05964
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989547
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906872
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57517
BRD-K85532500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55982
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78781
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.975183
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837328
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16265
small intestine	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05414181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.584
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23375
molecular_function	GO Molecular Function Annotations 2015	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	-1.0	-2.69085
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33075
BRD-K77032979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52307
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36796
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	1.05807
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07933
BRD-K55562948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51608
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15924535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41608
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10935
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18997
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51454923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79451
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998203
APP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K69269415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23955
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30863464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79019
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15543_KD_Map3k7/Chd1_SRP201304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.47375
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.08597
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05252
acetylsalicylic acid-1042	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18631401-TableS3	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3871
esculin-5411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226515
Rix1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1113
BRD-K44643967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2246
BRD-K78813464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45378
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17441
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18629
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918888
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.44182
BRD-K59571728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40399
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247823
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82682
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0473
WDR36	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135350_2_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38303
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10384_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.05473
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
R-atenolol-2496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0834
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12204
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleolus	LOCATE Curated Protein Localization Annotations	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858301
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33219
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30143
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46951445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67938
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08978
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4778-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856178
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30884
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2304
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11497
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15482
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44006
BRD-K04005364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37038
TTC30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08722
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4386
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18855
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882884
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.91685
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.341
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829479
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15053
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06169
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.62292
BRD-K97318603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01028
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01475
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1883_KO_Ogt_SRP250299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34793
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55581069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43724
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00343
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1056
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lanatoside C-3852	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.13963
fulvestrant-5926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.867251
BRD-K44921612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39984
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857803
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925522
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942052
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14971
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24705
THAP1	ENCODE Transcription Factor Targets	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K65399214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30498
FOXP3	ChEA Transcription Factor Targets	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92748
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78696
BRD-K36197756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0241
BRD-K74663731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6505
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843627
amiloride-1970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.87542
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8306
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54538111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38387
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56502
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
2633_EN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.577533
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11583
CRCGN016_MCF10A.TP53.M_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51818
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08223
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
daunorubicin-7511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3889
BRD-K25846934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47958
hsa-miR-298	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PAX8	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11525
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82763
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23033
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15716
Prostate adenocarcinoma_PRAD_TCGA-G9-6332-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835163
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17349
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1711
dipivefrine-7124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24233
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41022
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965806
BRD-K73995655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24234
valproic acid-1163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.946844
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-FOXM1_targets-Genes_n_696_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944174
PBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10191
BRD-K83645749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41974
BRD-K54939987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72732
BRD-K37379978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16622
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5299
cefalexin-5615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12642
HCC-202	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.95461
CRCGN015_MCF10A.TP53.M_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1185
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93598
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34807
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67379
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53065
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33469
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10212
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3929
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0153
BRD-K28467941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21228
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glycopyrronium bromide-7386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.980635
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-4237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38212
skin	GTEx Tissue Gene Expression Profiles	1.0	0.885906
hsa-miR-3591-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
amantadine-3280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RELA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3373
SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18191
BRD-K77832645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50409
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0123
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43416
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9073
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21785
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6539
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
CRCGN009_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06534
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40264914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08879
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03845
BRD-K47461610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70307
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20966
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58751
lanatoside C-6048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K43106305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07436
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35847
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444462
NIPSNAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85112460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12391
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.42565
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49424866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07079
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70566
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54252
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6956
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07753
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80075
PANC0403_PANCREAS	CCLE Cell Line Proteomics	1.0	2.24187
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.049
Perturb_6506_KO_PTEN_SRP299373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33337
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71718
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37969
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919299
POU2F2	ENCODE Transcription Factor Targets	1.0	null
mefenamic acid-5109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206225
LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
fluphenazine-5597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844302
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trichostatin A-2137	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63201
clozapine-1009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2819-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944412
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76927
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33921
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.68359
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.5251
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5647
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01854
troleandomycin-1965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15886
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.404
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28826
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	2.13285
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17353
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hycanthone-5691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL8108 (RAD54L2)	NURSA Protein Complexes	1.0	null
MMAc-SF	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.74015
7-aminocephalosporanic acid-3258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66963756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52745
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5354
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25021
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09972656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02935
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
PDK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503722
BRD-K03730976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89739
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
propafenone-1722	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32293
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
netilmicin-7302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BATF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923794
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.49731
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24352
Perturb_1100_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6861
Perturb_1650_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.57632
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24173
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995299
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877421
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76927
BRD-K04791118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00688
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383882
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22135
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.90695
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP214	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10672_KO_Gata2_SRP212686	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.09811
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.875079
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19865
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51228600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0766
GSE247862,GSE247863_4_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01096
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841986
HEC6_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	2.69531
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.856797
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89905
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48927
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888742
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.508
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71779
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.899091
CDK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520346
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2728
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14758
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68272
SARS-CoV MA15_Day2_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99468
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Avagacestat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125156
enoxacin-4655	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LAMTOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866089
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09568
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11118
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18389
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01155
KMS21BM	CCLE Cell Line Gene Expression Profiles	1.0	1.81627
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52189
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826142
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM133	BioGPS Cell Line Gene Expression Profiles	1.0	1.75965
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50761
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11242342-jcav15p4513s1.pdf-23-GABPA_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65705295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56282
estradiol_homo sapiens_gpl571_gds4063	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NDUFA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414574
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19809
tanespimycin-1643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acenocoumarol-1394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06733
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51521
BRD-K62979806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10006
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07316
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4584
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.035985
QE-48-NG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245147
prednicarbate-5544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29744
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874426
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52826
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83529
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55598155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98767
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73169
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.99267
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.231974
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26232
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31877
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19014
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13723
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.437766
RELA_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17968
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49288
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1079
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84975
Translation machinery-associated protein 16	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K29328556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31475
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6741
CRCGN015_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00589
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7021759-41467_2020_14682_MOESM8_ESM.xlsx-Upregulated_Genes-Table_S5_Upregulated_genes_in_MYCN_amplified_neuroblastoma_relative_to_non-amplified_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
furaltadone-3838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09224
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11362
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04397
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39982
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28697
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-561	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2373	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.16306
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08418
doxycycline-1113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-CH2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.38039
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26123
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-51-PY60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27453
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07635
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08697
AKR1C4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589168
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
crotamiton-3050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549576
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899208
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03658
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56839
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01301
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910774
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30516
phenanthridinone-1115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K63803358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09323
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47643
GSE49929,GSE49931_1_v_0_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9718
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00502
Ovarian mucinous neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
preribosome binding	GO Molecular Function Annotations 2023	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-1.29931
troleandomycin-1465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
prazosin-826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23629
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965704
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1973
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	2.64942
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86004
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34881
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10083
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24215
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.18435
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.6807
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amiprilose-3339	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
PMC10189495-mmc7.xlsx-TCF4_wk1-gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35076
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28111
Alcohol poisoning_Pancreas_GSE3311	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.987735
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91656
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32102
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
guanabenz-2045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AB-84-PK04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293576
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61758
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.962202
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.22072
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07736
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.733
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
dacarbazine-6816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K09721398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51093
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70858
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82442
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12654
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.76676
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant-5202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31923
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910346
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2963-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71216
capsaicin-3372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41551
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56113
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4250-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fluocinonide-4314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-1221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21948
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.997481
GNL2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
5255229-833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32635
PMC10025425-mmc3.xlsx-ADNP_WH-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578752
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23501
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46566
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24567
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84173
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864171
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22118
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09027
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.51114
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.317557
Uterine adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.528611
CRCGN016_MCF10A.TP53.M_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20566
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
conessine-2135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72580121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47377
hsa-miR-217	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834499
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06403
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-562	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58825
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.80108
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71062
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22293
FOSL2	ENCODE Transcription Factor Targets	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938394
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32379
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13576
hsa-miR-3689b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.18972
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11772
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15214
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_TIP60_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17825
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36878
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4886
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212053
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71726
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10262
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13831
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10151
DU145	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75047
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epilepsy_lymphoblast_GSE7486	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.7089
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02056
BRD-K61052964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76017
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13248
convolamine-1779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480151
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92003
SPI1	ENCODE Transcription Factor Targets	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3323
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06549
BRD-K05154886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72062
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828152
fulvestrant-5235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COV362	CCLE Cell Line Gene Expression Profiles	1.0	3.37398
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22238
withaferin A-4554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332057
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19347
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A7TX-01A-33R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.39806
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929514
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_0_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940793
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84794
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10424
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96347
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1768
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9256
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41724
opm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
ELK1	ENCODE Transcription Factor Targets	1.0	null
valproic acid-348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1838	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.18985
BRD-A38359809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17198
GSE114992,GSE114993_4_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22988729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13086
Superior colliculus, motor related, intermediate gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03171
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10313
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0381
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29985
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01999
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910021
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67246
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56708
heptaminol-6015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57014767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59901
Intrinsic component of peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.745
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K41674016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1099
KRI1	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenindione-2868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
trichostatin A-2330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34256721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01911
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845659
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886867
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45499
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HAUS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0043
ethaverine-3037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CF-91-JY05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309407
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ribosome biogenesis	GO Biological Process Annotations 2023	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07635
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05572
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47399
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74641
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K96379403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21195
astemizole-2211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0331
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22316
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eucatropine-3416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36912
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0787
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16067
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978605
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81706
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12765
BRD-K92791036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93822
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27335
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48943
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KDM5A	ChEA Transcription Factor Targets	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16968
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35016
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25688
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30143
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41663
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15350548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47176
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33879
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54602
riboflavin-4485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37542
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8986
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.53983
HCFC1	ENCODE Transcription Factor Targets	1.0	null
fusidic acid-1293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hl60	HPA Cell Line Gene Expression Profiles	1.0	1.1611
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20741
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57059449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07601
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1292
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K78816149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31711
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
N-acetyl-L-leucine-6462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K00363054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67623
tolnaftate-2001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKBKG	Hub Proteins Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.28303
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
menadione-2439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chicago Sky Blue 6B-3266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16118
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52713598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55531
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37713
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4X2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79688
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85779
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8963_TMA16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.671951
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44298652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41662
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36308
KS-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.25355
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64353470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07506
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
valproic acid-989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880657
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971408
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20754
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.37154
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41584
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42511
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41964
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0886
organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31363
CTCF	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37454185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56616
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48672
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50668
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62024
BRD-K46162352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0301
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.0877
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935282
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ramifenazone-6097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06394
Sarcoma_SARC_TCGA-IW-A3M4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95495
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04851
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8426
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.36926
hsa-miR-3123	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.36989
KYSE270	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06602
chloropyramine-4414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68202226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58097
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22321
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28763
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83394
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08224
BRD-K54141134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16077
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1422
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.247
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943051
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77281
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67336
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.52194
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.08619
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22972
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86593
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.46862
BRD-K58892587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60122
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28776
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110802_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29822
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01045
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82972
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49435
hsa-miR-425	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KARPAS422	CCLE Cell Line Gene CNV Profiles	1.0	1.49265
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01141
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20115
NR2F2	ENCODE Transcription Factor Targets	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61279
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4856
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.21759
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEDD4L	Pathway Commons Protein-Protein Interactions	1.0	null
cefalonium-2921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.10734
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HIST2H2AA4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22748
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05613
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47579
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839438
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFO27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56921
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.927007
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898616
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1432
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7575
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6724
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66482
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKHEP1_LIVER	CCLE Cell Line Proteomics	1.0	2.09614
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4286
PMC12721900-jci-136-187998-s161.xlsx-Flag-ETS1_vs_vector-Gene_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78239
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.239
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15209
MAX_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03732
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896866
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14623
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915455
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0773
trichostatin A-2523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59634
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39853
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12964
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28314
NCI-H146	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44385
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tanespimycin-1167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trichostatin A-1212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21284411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85787
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967439
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28972
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44002
BRD-K44309337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57065
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8958
BRD-K04877855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20487
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100598_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15604
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2759
BRD-K63025696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63682
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60453579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74413
PPP1R10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10404
SLCO1B3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506861
BRD-K80176886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52825
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43894
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53105
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.961056
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933925
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14942
BRD-K58791506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31995
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907221
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06903
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1871
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24528
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26934
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44648
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46271
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832543
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928307
Prestwick-692-4424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08737
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42471
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23958
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5738
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86889
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NLS-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02288
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brompheniramine-1335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10872
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	-1.0	-1.00125
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8105
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855528
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7588-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.36184
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70097
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-7136	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5893-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02833343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14112
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.232
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15222
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ergocalciferol-3304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06094
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38421
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04863
cefotetan-4116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE60691_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.346
GSE148066,GSE157787_2_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89471250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11708
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LU65	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52796
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31461
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38917
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458522
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22796
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_6_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9529
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53251
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18168
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.64891
tranylcypromine-5996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615752
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5898
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35688
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21767
BRD-K12913157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60849
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NTRK2_drugactivation_66_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81484
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85367
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01231
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49534
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32257
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47277
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4446
SIRNA_EIF4GI	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VDR	ChEA Transcription Factor Targets	1.0	null
hsa-miR-92a-3p	MiRTarBase microRNA Targets	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19309
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978605
BRD-K28276275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03679
Lung squamous cell carcinoma_LUSC_TCGA-66-2782-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00562
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941044
piperacetazine-7191	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.631
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897409
CMK115	CCLE Cell Line Gene Expression Profiles	1.0	1.53014
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13812
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0067
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56802
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11614
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54143
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00450666
GSE218060_7_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54478142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02739
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30646
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11153
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42318
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.35731
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05483
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869262
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71286
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45723
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870268
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82524
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88832
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76927
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50927
BRD-K97332312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40357
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68136
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62264
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14087001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31655
FAF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54371
BRD-K73443280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67422
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19505
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8141032-NIHMS1694738-supplement-Supplementary_Table_1.xls-MYC_BAF155_BRG1-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07933
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59891
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.85845
NME9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056718
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00806
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218060_5_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfafurazole-1603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1529
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07783
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26192
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25006
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20161
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92178
BRD-K43029808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07806
chlorpromazine-1158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDIK1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570781
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99772
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986592
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04854
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Noc4p-Nop14p complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.006
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92036
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23872
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.031
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01009
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12134
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82345
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5185
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03665
BRD-K53953065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14296
HNF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04481
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-Curated_GSEA_gene_sets-TAL1_SANDA_ET_AL_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06237
BRD-K37634338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88828
resveratrol-1715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_WT-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid-6173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827962
Prestwick-1085-3554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K27320944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.942
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4856
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232911
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29527
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22337
TE-6	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.38679
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22978
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_2_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ceforanide-3309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
palmatine-2138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21447
BCKDK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	1.0	0.916372
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
perphenazine-4637	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A59449038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35254
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74860368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85652
nordihydroguaiaretic acid-1164	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281168
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.8467
CRCGN015_MCF10A.WT.HP_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52655
FUNDC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936608
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49529
PMC3371315-NIHMS350140-supplement-11.xls-MCF7-T47D-SK-453_Up_SK-453_xls-Supplementary_Table_4_ER-negative_FOXA1_signature_Genes_increased_only_in_MB-453_and_SKBR3_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01229
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_184_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.26878
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7049
OUMS23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9852
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76296
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11656
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
methacholine chloride-3452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7164
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.70335
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78076
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03911
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.61353
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19085
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04178
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79184
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27825
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00794
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61427
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35668
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H748	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.71734
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07852
alpha-estradiol-1151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995299
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26059
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-11-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224517
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07802
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66593
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.112
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02261
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977593
trichostatin A-4483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46756
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88012
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06879
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09606
GPC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540049
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1897
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50291
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
tcf12_20154672_cd4pos_cd8pos_thymocytes_thymus_lof_mouse_gpl6246_gse19923	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.009381
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44064
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07006
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.18791
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.40481
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79781106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39191
BRD-K55728478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2225
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1119
minocycline-1135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55762
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37465
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAY-10397-7087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78639
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM2313	BioGPS Cell Line Gene Expression Profiles	1.0	1.59322
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910155
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857209
CRCGN015_MCF10A.TP53.M_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04832
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.62911
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haloperidol-2039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933771
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978605
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28876
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47799
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3689f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K21866464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28209
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3599
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35352
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pirenperone-4679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.82663
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pentetic acid-5629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41709602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.87072
BCB000040-7493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0288
GSE148066,GSE157787_3_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03542
BRD-K06718330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28663
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33676
tetraethylenepentamine-412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42726
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Box H/ACA RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89155
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47058
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01138
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992624
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02099
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PABPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00732187
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77941
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPAP2	Pathway Commons Protein-Protein Interactions	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850793
HT-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.33452
glycopyrronium bromide-4709	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04325
tomatidine-7166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35063
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05621
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHA-00846566E-7086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62607
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02291
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33243
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gibberellic acid-2910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68338
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926842
BRD-A87494167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01958
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.01625
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HSF1_KD_GDS1733_750_human_HeLa cells - 0 Hour	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EM2	CCLE Cell Line Gene Expression Profiles	1.0	1.72425
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057585
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.843533
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08173
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42722
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8220302-mmc2.xlsx-Enriched_in_PPAR_activation-T_Gene_names_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43761
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56931
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01474
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924646
hsa-miR-543	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
diclofenac-7215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1S	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18078
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99529
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939261
hsa-miR-3689a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K84062787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50107
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SG-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54863
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50827
fulvestrant-7091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05825
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92848
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null