association dataset threshold value standardized value Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5726 Sertoli cell-only syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76765 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.849666 SIMA CCLE Cell Line Gene CNV Profiles -1.0 -1.94979 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828403 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07448 BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5438 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65919 NCIH209 CCLE Cell Line Gene CNV Profiles 1.0 1.47669 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH510 CCLE Cell Line Gene CNV Profiles 1.0 1.5168 KLF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86836 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GRIK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49626 SOX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5078 Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.786 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879118 NT5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22265 TEX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40798 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNAJC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13568 Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0472 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1497 ZNF880 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38289 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879118 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925571 TMEM254 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91999 PPRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65122 BTBD18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71501 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21208 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47042 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3485 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null B9D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27574 GSE171179,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTFR1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39872 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null TWF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50391 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.66225 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09833 MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SPIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71769 CREB1 ENCODE Transcription Factor Targets 1.0 null 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.948 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5186 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 1.61304 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854786 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.51268 MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3208 C19orf44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13757 PIAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54088 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96605 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61227 KDM4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7052 GSE211286_1_v_5_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.048 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5264 LIG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68769 membrane LOCATE Predicted Protein Localization Annotations 1.0 null CCND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87272 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28805 GATA2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null Dlx5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2237 SERPINB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98646 ARL4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95341 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827708 TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null VMRCRCZ CCLE Cell Line Gene Expression Profiles -1.0 -1.60897 YIPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95901 GCT CCLE Cell Line Gene Expression Profiles -1.0 -2.83569 ZNF592 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58352 Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07076 CENPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62546 MAZ ENCODE Transcription Factor Targets 1.0 null Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.1525 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65549 HCC33 CCLE Cell Line Gene CNV Profiles 1.0 2.6926 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.810317 CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF274-21170338-K562-HELA ChEA Transcription Factor Targets 2022 1.0 null ZNF605 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18337 CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.16238 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.6467 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23091 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5475 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74557 BLOC1S6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91553 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15654 PRMT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01492 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF557 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56706 GNG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20211 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.45 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13647 Spermatic cord torsion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.231 FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO824 DepMap CRISPR Gene Dependency 1.0 3.38128 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -2.4742 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00267 HSFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07638 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.16253 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VO-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRCA1 ENCODE Transcription Factor Targets 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42692 UBE2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48559 Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100359_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.78752 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3434-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PURG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96995 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88083 SETD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97153 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYAE1 DepMap CRISPR Gene Dependency 1.0 5.85439 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11903 RKO CCLE Cell Line Gene Expression Profiles 1.0 1.39742 RASSF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01859 C2BBE1 CCLE Cell Line Gene CNV Profiles -1.0 -1.92131 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.891159 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9285 EHMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92291 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.899107 GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBXN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17196 ANKRD46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52542 Lung squamous cell carcinoma_LUSC_TCGA-46-3766-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917437 Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL5 DepMap CRISPR Gene Dependency 1.0 3.11489 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8356 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5057 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00991 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null YD8 DepMap CRISPR Gene Dependency 1.0 3.82081 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 CIT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03749 L363 CCLE Cell Line Gene Expression Profiles 1.0 2.55694 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988395 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.956 PMC3348545-NIHMS263168-supplement-3.pdf-40-POU3F1_POU3F1 Rummagene Transcription Factor Associations 2026 1.0 null RT112 CCLE Cell Line Gene Expression Profiles -1.0 -1.61277 UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39395 ZNF37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23222 GSE127790_4_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -1.06108 ZNF879 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26692 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15654 CCNYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61697 RNF34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28943 TMEM179B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98841 KDM5A ENCODE Transcription Factor Targets 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43728 TOMM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40986 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.7697 MFE296 DepMap CRISPR Gene Dependency 1.0 3.47482 ORAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40333 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7251 Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9534 DNTTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16287 THAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30878 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51045 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4097 NCI-H510A COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3 BFTC905 CCLE Cell Line Gene CNV Profiles 1.0 1.99743 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KIF5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925571 integral component of membrane GO Cellular Component Annotations 2015 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17875 496100348_TCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.53787 ZNF699 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45142 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71132 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.6724 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.55121 THAP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66462 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.4587 MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18171 496100541_FWM_possible Alzheimer's disease_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06519 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HJ-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26647 GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4378 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ACTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90997 stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.8663 CDKN2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18954 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null Medial geniculate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.769 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933496 CALM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98828 TDRD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69043 HK2 CCLE Cell Line Gene Expression Profiles 1.0 2.30675 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100488_TCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24789 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ACER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3475 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1777 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null ELOVL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54013 Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.851119 POU2AF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09754 SLC39A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69703 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979348 KLK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77323 gata4_21746915_heart_lof_mouse_gpl6246_gds3931 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.21018 Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202359_1_v_0_rbpms_mouse RummaGEO Gene Perturbation Signatures 1.0 null EEF2KMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40706 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02041 ZNF79 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96694 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14582 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.8683 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null C1orf54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93747 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84865 FYCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98122 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925571 PARP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58461 CREB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.035 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8585 COLO205 DepMap CRISPR Gene Dependency 1.0 4.51774 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9211 Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912375 TOR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81921 496100333_FWM_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86509 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus GO Cellular Component Annotations 2025 1.0 null Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.0915 SP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78782 CNDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02148 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RHOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31705 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36076 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872153 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5751 LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.03498 CLNS1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08206 RFX5 ENCODE Transcription Factor Targets 1.0 null H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TNIK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12203 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RRBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98689 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.891159 PPP2R2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20969 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DCAF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31399 ETNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33914 IL6ST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81258 NRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11476 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5075 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979348 CEBPB ENCODE Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null postcentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13913 Multiple epiphyseal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.271 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832588 SPRED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54638 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HL60 CCLE Cell Line Gene Expression Profiles 1.0 1.77181 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02756 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ERBB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02293 SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3201 CYC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16431 ALKBH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75387 PA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXD4L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.30813 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22263 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.8889 RNF146 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71855 GSE180200,GSE180201_5_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH520 CCLE Cell Line Gene CNV Profiles 1.0 1.73946 496100323_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08411 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.852668 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.121 Riley-Day syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14147 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3949 CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15946 UBTF ENCODE Transcription Factor Targets 1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27937 TBX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.52476 RCOR1 ENCODE Transcription Factor Targets 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null DDIT4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59285 PTER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77138 GSE180200,GSE180201_5_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22155 precuneus, right, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12079 KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.46863 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07076 angular gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.837062 FAM50B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66145 Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11903 GSE162892_4_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null SA1-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH69 CCLE Cell Line Gene Expression Profiles -1.0 -1.96428 ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.323963 UNC5CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55219 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.3098 ELOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06848 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP1 ChEA Transcription Factor Targets 1.0 null SLC25A30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89666 Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8473 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAP2K7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95595 GSE140092_0_v_1_socs3_mouse RummaGEO Gene Perturbation Signatures -1.0 null DETROIT562 CCLE Cell Line Gene Expression Profiles -1.0 -1.76273 kidney GTEx Tissue Gene Expression Profiles 1.0 1.24796 Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null PNPLA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14675 BNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78836 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null THP1 CCLE Cell Line Gene CNV Profiles 1.0 2.20539 CCDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15518 TCF7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05123 SNU245 CCLE Cell Line Gene CNV Profiles -1.0 -1.49342 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HMGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11614 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SKN3 DepMap CRISPR Gene Dependency 1.0 3.14143 JAR DepMap CRISPR Gene Dependency 1.0 2.00386 JHH5 CCLE Cell Line Gene CNV Profiles -1.0 -1.40413 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.59804 GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70019 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.10291 DOT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6464 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SNU81 DepMap CRISPR Gene Dependency 1.0 13.2258 ALOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85915 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.49118 Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01578 TAL1 ENCODE Transcription Factor Targets 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31387 RPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75851 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null PAOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16438 TDRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51651 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54974 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.909922 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.569 HDAC1 ENCODE Transcription Factor Targets 1.0 null CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.342 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26269 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6793 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CASC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92679 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03153 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 3.40795 ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04153 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21888 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11584 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2494 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.04972 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZNF384 ENCODE Transcription Factor Targets 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.886708 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6768 MOGGUVW DepMap CRISPR Gene Dependency 1.0 2.49672 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43663 granular layer of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19921 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TERF2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61352 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04209 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH2029 CCLE Cell Line Gene CNV Profiles 1.0 1.92905 HYAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24503 RBM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19595 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06791 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55837 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4487 SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.76067 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.03747 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.624287 PAX5 ENCODE Transcription Factor Targets 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17661 SHROOM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86217 Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNAP47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25281 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.988108 Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.29517 FOXD4L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11486 496100375_FWM_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.83033 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835731 RAB40A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99315 ZNF107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27108 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PL45 CCLE Cell Line Gene CNV Profiles -1.0 -1.61747 ZNF562 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44809 GSE131649_4_v_5_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73B-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94783 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.2886 NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33373 eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF277 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36372 SHPRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01081 ANKZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55118 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895627 496100403_TCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.50001 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68981 UQCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.401 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.6514 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35756 EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.4696 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Oligoasthenoteratozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 DMS53 CCLE Cell Line Gene Expression Profiles -1.0 -1.78141 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTEN_01_301 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59066 CEP78 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74984 Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22263 SERPINF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33778 RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TRA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34052 small intestine GTEx Tissue Gene Expression Profiles 1.0 0.858864 YY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25131 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37399 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26996 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02843 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21678 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72687 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A267-06A-21R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4331-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23452 ESS1 CCLE Cell Line Gene Expression Profiles -1.0 -1.67843 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 SRSF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95777 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21444 ATL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41825 PCI6A DepMap CRISPR Gene Dependency 1.0 2.40871 LHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29919 RAPGEFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52986 TUBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7536 PPP4R3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69155 EBF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92505 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10964 KMRC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.77268 CORL24 CCLE Cell Line Gene CNV Profiles 1.0 1.76238 SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.92237 EPOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96372 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37063 PNPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68953 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC9 DepMap CRISPR Gene Dependency 1.0 6.70699 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.78668 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.13186 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.42002 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null Ectoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.906 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59872 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.00771 TP63_01_200 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.397 OE33 CCLE Cell Line Gene CNV Profiles -1.0 -1.46481 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 ADRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63127 SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.55764 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.364 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 FOXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88783 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 1.46962 SNU685 CCLE Cell Line Gene Expression Profiles -1.0 -1.78825 Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9643 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38771 Lung squamous cell carcinoma_LUSC_TCGA-60-2711-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95078 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.996251 IMPACT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91616 Orchitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.023 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF1 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77752 BTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31316 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.25214 Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34936 znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.611256 CARNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70561 GPR120_KO_GDS4830_413_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47038 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5661 Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B6-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61376 H3K27me3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH82 CCLE Cell Line Gene Expression Profiles -1.0 -2.58137 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRMT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93588 TSC22D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69558 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63 JASPAR Predicted Transcription Factor Targets 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null CAPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06399 Lung adenocarcinoma_LUAD_TCGA-55-8621-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62316 Siphon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.964 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03889 Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100453_HIP_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.74814 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6142 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE280 DepMap CRISPR Gene Dependency 1.0 4.88085 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCAMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27164 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8399 ABCF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58469 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2563 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00015 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 GSE143994_2_v_1_ythdf1_human RummaGEO Gene Perturbation Signatures -1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16423 LRRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04695 REXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.087 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68831 BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PJ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62316 Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1963 CCLE Cell Line Gene CNV Profiles 1.0 2.36423 HNF4A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tail TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.88 HSCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18912 nucleus GO Cellular Component Annotations 2023 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.954092 Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65V-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSORS1C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99541 outer SZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928201 GSE127790_10_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6975-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80291 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUDUL1 CCLE Cell Line Gene Expression Profiles 1.0 1.84453 MZ in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.824427 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.31171 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173201_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1963 CCLE Cell Line Gene Expression Profiles 1.0 2.00291 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hoxa13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.8984 HDAC2 ENCODE Transcription Factor Targets 1.0 null PATU8988T CCLE Cell Line Gene Expression Profiles -1.0 -1.57826 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -2.17947 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8069_KD_SFPQ_SRP281189 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.56524 DMAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15273 BEND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79365 PC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 NCI-H1876 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 NCIH2170 CCLE Cell Line Gene Expression Profiles -1.0 -2.14039 CACO2 CCLE Cell Line Gene CNV Profiles -1.0 -1.65884 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98484 FLOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29663 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC26A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18956 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58656 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866347 HNF4A ChEA Transcription Factor Targets 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.91091 PMC6063960-41598_2018_29472_MOESM5_ESM.xlsx-lightcyan_module_HF-DMRTB1_DMRTB1 Rummagene Transcription Factor Associations 2026 1.0 null inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14654 Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88016 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08498 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16926 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KIF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.234 ECGI10 CCLE Cell Line Gene CNV Profiles -1.0 -1.39361 ZNF33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01079 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2433 FBXO33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06775 OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.7367 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.93991 CHMP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37451 BAIAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.301 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.67405 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.53963 GUCA1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81151 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07896 bp86 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.336 496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.39858 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.850262 LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TMEM184B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17871 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936285 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.454 PEO4 DepMap CRISPR Gene Dependency 1.0 2.08527 Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6822 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE89767_2_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77809 ERF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42486 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979348 SERPINB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19324 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3313 Hepatopancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SEC24D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74631 EKVX CCLE Cell Line Gene CNV Profiles 1.0 1.39373 ZBTB45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17395 RBM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54489 PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0201 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8297 NKX6-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02165 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37153 GATA2-21666600-HMVEC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE149264,GSE149267_9_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.920509 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HM-01A-12R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1067 GATA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08335 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.25654 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.5633 CAVIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13457 GSE127790_10_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.875542 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.949709 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCAI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84631 PRORP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84699 SCHNEIDER-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.947 COR-L88 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.82625 RBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47228 ZNF260 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67873 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0348 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02007 CTCF ENCODE Transcription Factor Targets 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.74654 GNPDA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57553 Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS-273 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 ADNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46339 ZNF274 ChEA Transcription Factor Targets 1.0 null CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.24354 inferior frontal gyrus, opercular part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.830186 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 FBLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21975 DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 1.5575 MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.71696 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.62483 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4327-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.90439 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3264 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865215 ZNF761 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22225 COLO-741 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHU022 DepMap CRISPR Gene Dependency 1.0 3.56622 HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07076 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21352 MAP3K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22324 CHST6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53428 496100633_TCx_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.52161 PRMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12756 Intercalated nucleus of amygdala Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934063 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF786 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48806 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975303 KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -2.08275 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CD151 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07706 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5591 YWHAQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1702 PHACTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47187 TEKTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02369 HYCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49202 HNF4G ENCODE Transcription Factor Targets 1.0 null ZNF497 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92643 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OE19 CCLE Cell Line Gene Expression Profiles -1.0 -3.06387 DHX36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56982 PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null ANO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7162 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9619 A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.37561 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22155 ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73636 SDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36863 FANCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59459 BRMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06098 ACSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61999 EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRC_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 cell part GO Cellular Component Annotations 2015 1.0 null TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.17765 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.883912 ZNF785 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27319 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.74778 MSLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63673 PNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8152 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.981133 SARS-BatSRBD_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.67909 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH226 DepMap CRISPR Gene Dependency 1.0 2.46309 TMK1 DepMap CRISPR Gene Dependency 1.0 9.78534 H2AFZ ENCODE Transcription Factor Targets 1.0 null PDZD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8817 SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.29366 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893671 Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THUMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46398 TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30294 WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.7758 ELP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84454 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.666 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3778 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.585 Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03477 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null PRKCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5802 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.0169 IZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.857375 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978492 Vesicoureteral reflux DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 ZNF488 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80461 RIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18347 TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HES3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64922 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9362 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3721 TM9SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34906 intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66817 BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GYG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51791 496100502_TCx_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.69393 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.832292 YD8 CCLE Cell Line Gene CNV Profiles 1.0 1.66566 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100650_TCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6702 TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF705D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79553 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39924 SMC3 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69778 EARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00867 Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WTX_OE_GDS4802_34_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NEFH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44261 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null ISCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36115 CUX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68696 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02041 496100530_FWM_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08213 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45215 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null DLD1 CCLE Cell Line Gene Expression Profiles 1.0 1.44153 intracellular part GO Cellular Component Annotations 2015 1.0 null OVCAR4 CCLE Cell Line Gene Expression Profiles -1.0 -1.90966 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835731 496100667_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.14237 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12703 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null UAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62178 EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12962 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0079 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8 ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCIRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60988 PITPNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79533 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SF126 DepMap CRISPR Gene Dependency 1.0 3.0214 TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.80169 AMER1_OE_GDS4802_549_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.91147 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF491 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11643 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.967625 NH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.89269 DTYMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83299 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QC-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41751 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.934124 KIJK CCLE Cell Line Gene Expression Profiles 1.0 2.28688 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31387 TBP ENCODE Transcription Factor Targets 1.0 null GATA3-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25396 lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854067 HSPB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76502 Brain Lower Grade Glioma_LGG_TCGA-P5-A72X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null SOCS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80192 A_CA_04_2009_4dayMOI-10^4_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.53756 Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59283 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32396 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9365 GATA2-21666600-HMVEC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5081 Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 XPO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07526 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 PCI30 DepMap CRISPR Gene Dependency 1.0 2.25809 ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6699 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3125 PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null Egg coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.761 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RAB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60698 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.856815 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23933 Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07198 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null breast GTEx Tissue Gene Expression Profiles 1.0 1.66707 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59955 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46853 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0707 HIF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09506 CD320 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99887 A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.76183 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.839433 FOXF2 JASPAR Predicted Transcription Factor Targets 1.0 null SNUC1 CCLE Cell Line Gene Expression Profiles 1.0 2.14009 TMEM92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7817 MTA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73974 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2476 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.964106 CSDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57874 FOS_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX39A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.5781 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.764 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null HCCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11647 DNMT3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80589 CAL851 CCLE Cell Line Gene Expression Profiles -1.0 -1.68126 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.02058 SF539 DepMap CRISPR Gene Dependency 1.0 2.22385 EW1 DepMap CRISPR Gene Dependency 1.0 8.54993 ZNF516 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27076 PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1 Rummagene Transcription Factor Associations 2026 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.598 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2023 Axonemal microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.823 GATA6-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FBXW4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43182 GSE146894_3_v_8_hira_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16926 CKMT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88018 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null p3u1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.347 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6273 TIAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21924 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.00513 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF274-21170338-K562_HELA_HEPG2_GM12878-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RAB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60581 hsa-miR-4643 TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.872 HOXA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57349 JUND_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null THP-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 PNRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09139 SNGM CCLE Cell Line Gene Expression Profiles -1.0 -1.55345 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73707 WDR5-24793694-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2221 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 ZNF212 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75776 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.12545 Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2810 COSMIC Cell Line Gene Mutation Profiles 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.24839 HTR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57928 TGFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39417 PCGF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03756 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6023 FIGLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63014 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6156 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM127 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75062 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.92869 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1546 GRHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0032 GOTO COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 TSSK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98452 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37705 VMRCLCP CCLE Cell Line Gene CNV Profiles 1.0 1.58124 PNMA6F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66796 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SETD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75208 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11903 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A84U-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88365 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4282 HASPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68982 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48348 Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5133 EW8 CCLE Cell Line Gene Expression Profiles 1.0 1.41221 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.52998 Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42071 TE441T CCLE Cell Line Gene CNV Profiles -1.0 -3.05183 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09833 SP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.932272 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XG-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2029 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 OTUD7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8295 SRF JASPAR Predicted Transcription Factor Targets 1.0 null NYAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54851 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.932879 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835731 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4169-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNUC1 DepMap CRISPR Gene Dependency 1.0 2.3009 ZNF24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19706 Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.827708 NR2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88045 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149264,GSE149267_4_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null EB2 CCLE Cell Line Gene Expression Profiles 1.0 1.38744 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.849025 EZH2 ENCODE Transcription Factor Targets 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5185 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11903 inferior frontal gyrus, orbital part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.875042 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.65262 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1092 CCLE Cell Line Gene CNV Profiles 1.0 1.88371 NCI-H1963 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 NPIPA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79092 DMS153 CCLE Cell Line Gene CNV Profiles 1.0 1.55492 CNNM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19852 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.9954 FAM91A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63405 DDX3Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62084 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.6196 NACA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78296 KIF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09943 LS1034 CCLE Cell Line Gene CNV Profiles -1.0 -1.46101 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17661 CHMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28634 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49508 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29582 Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00374 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7578 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09102 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.834883 SMAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07061 H2BC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32958 YES1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1592 MTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60048 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Hoxd13 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.9808 ECE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62606 TRIO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88726 icSARS-Cov_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63695 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.934804 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79667 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878376 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978492 SAP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6787 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15304 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.31354 A-Vietnam-1203_CIP048_RG3-2004(H5N1)_24Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.44198 H3118 DepMap CRISPR Gene Dependency 1.0 7.29174 agranular insular cortex (area Iag) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.918119 EGR1 ENCODE Transcription Factor Targets 1.0 null LARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30735 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83S-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null ERG_01_17 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.72247 cell part LOCATE Predicted Protein Localization Annotations 1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2245 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01558 PTEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77463 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.98468 Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89323 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6601 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09744 KDM5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29246 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21397 SP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890227 GRHPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64351 FZR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22105 SCH DepMap CRISPR Gene Dependency 1.0 6.52046 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04274 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07076 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31512 SBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80218 LS123 DepMap CRISPR Gene Dependency 1.0 4.20487 Kidney Chromophobe_KICH_TCGA-KO-8403-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46766 CHD1 ENCODE Transcription Factor Targets 1.0 null 496100396_HIP_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42125 Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55988 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.857977 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20187 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38792 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17571 MOGGUVW CCLE Cell Line Gene Expression Profiles -1.0 -1.61033 Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC17A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45532 HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.602534 MDAMB468 CCLE Cell Line Gene CNV Profiles 1.0 1.37373 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0354 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06111 NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3644 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45128 SOX12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8557 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF836 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66064 GSE180200,GSE180201_5_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37441 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GLI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42927 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4332-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF852 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84741 IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84385 RAP2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8752 SOX2-22085726-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50835 HLCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92098 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased circulating fructosamine level MGI Mouse Phenotype Associations 2023 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.2819 APIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73086 Perturb_5955_KD_RBMX_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.95434 HNF4A ENCODE Transcription Factor Targets 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.87182 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 OLFML2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90726 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.63828 HT1376 CCLE Cell Line Gene CNV Profiles 1.0 1.42986 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4548 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5886 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.99 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86908 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72059 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null GSE157960_2_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18177 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0611 NMRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62739 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00443 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84481 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.071 GSE155567_2_v_0_cd33_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4848-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162892_4_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1184 CCLE Cell Line Gene CNV Profiles 1.0 1.67438 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3771 TCEAL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03628 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.14759 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71641 LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01925 SLC1A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9803 MTARC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78623 ZNF283 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9703 NCI-H520 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6079 CAL-148 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE127790_6_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GADD45GIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35177 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93414 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27085 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.997 Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895363 CUX1 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03702 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A633-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99301 Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8953 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1958 CL34 CCLE Cell Line Gene Expression Profiles -1.0 -1.69106 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null long insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.907561 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835731 MON DepMap CRISPR Gene Dependency 1.0 2.67865 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8695 LUDLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.41366 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3313 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17661 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978492 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.1667 VMRCLCD DepMap CRISPR Gene Dependency 1.0 2.38695 F11R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0751 TTLL12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71007 Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF512B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60523 Sarcoma_SARC_TCGA-VT-A80G-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.492 ZNF169 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12441 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ITGB3BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09375 FOS ENCODE Transcription Factor Targets 1.0 null parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.87986 GRAMD1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.73452 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8246 ANGEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95186 PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIP4K2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.555 COLO-668 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 SCARB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89102 RAB32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53096 GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX7_OE_GDS3300_123_human_HESC (CA1 and CA2) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H748 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872153 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.056 MAFF ENCODE Transcription Factor Targets 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IH-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC2A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9788 PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 LASP1NB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80581 SOHLH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51278 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978492 NUDT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58209 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2 ChEA Transcription Factor Targets 1.0 null APPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87836 Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.025 MAPK13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61472 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTLL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47942 JUN_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.971 PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SIPA1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62621 CRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12061 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06177 FAAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20576 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07524 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.68054 CORL88 CCLE Cell Line Gene CNV Profiles 1.0 1.81839 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23406 NRSN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07431 MTHFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89327 ZNF671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42833 ZNF517 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43137 MHHCALL3 CCLE Cell Line Gene Expression Profiles 1.0 1.54828 Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 1.94968 KE97 CCLE Cell Line Gene Expression Profiles 1.0 1.65801 NUFIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35494 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HSF1_01_155 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.8701 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.4249 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6335 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17661 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1429 inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.971206 ATIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56334 Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987578 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 LIPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85294 Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17661 medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16183 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21238 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5 decreased circulating fructosamine level IMPC Knockout Mouse Phenotypes 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.23 AQP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68371 Perturb_15979_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.7798 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.068 centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25954 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.53269 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PROSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78656 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06569 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tail muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.192 Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARH77 DepMap CRISPR Gene Dependency 1.0 3.33178 PPP2R5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32861 CAPAN1 DepMap CRISPR Gene Dependency 1.0 11.671 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2419 Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3647 STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80056 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.978492 Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRFN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56189 PANC0504 CCLE Cell Line Gene Expression Profiles -1.0 -2.07331 HCC-33 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCM6 CCLE Cell Line Gene Expression Profiles 1.0 1.61638 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB415 CCLE Cell Line Gene Expression Profiles 1.0 1.36507 NCI-H250 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896475 Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BFTC-905 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15654 ZNRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50761 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1336 NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 1.49578 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RASSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17322 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.6917 TRPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51952 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF790 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54608 intracellular organelle GO Cellular Component Annotations 2015 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6145-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCaRG_OE_GDS2426_711_human_HEK293 kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TestisLeydigCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.16116 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55154 SCARF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13478 IMR32 CCLE Cell Line Gene CNV Profiles -1.0 -2.41117 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GAREM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7601 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRDX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72195 BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.0563 KYSE220 DepMap CRISPR Gene Dependency 1.0 6.87321 STX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 ZNF205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08363 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.9898 Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.541 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100332_HIP_possible Alzheimer's disease_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18351 JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86281 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11903 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TRIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92216 HJURP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30918 DMS273 CCLE Cell Line Gene CNV Profiles 1.0 2.09876 HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 1.42979 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PNMA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48356 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87681 hsa-miR-2117 TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 ETF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68219 TPRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42388 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6793 hsa-miR-875-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 nucleus GO Cellular Component Annotations 2015 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0103 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.35898 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX Rummagene Transcription Factor Associations 2026 1.0 null VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.856695 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HNF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36517 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03859 Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3516 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4849-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6994 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10385841__F5 PFOCR Pathway Figure Associations 2024 1.0 null A_CA_04_2009_4dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.91091 KLE DepMap CRISPR Gene Dependency 1.0 2.41814 PHF5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60161 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7187 Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54371 RRAGC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89341 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4701-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C8orf82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35718 PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Interacting_Gene_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null NCBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08643 FOS JASPAR Predicted Transcription Factor Targets 1.0 null SMCO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70044 KU1919 CCLE Cell Line Gene Expression Profiles -1.0 -1.77482 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2381 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.7301 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 2.8347 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.898034 FAM171B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38803 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.983292 OPLAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65888 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.86 B4GALT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51999 ZIC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12611 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8881 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE149264,GSE149267_2_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56081 TESK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97193