association dataset threshold value standardized value GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25908 ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null retromammillary area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00142 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29912 USF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47157 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.71938 RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDR1_knockdown_169_GSE39207 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.70889 SIRT3_KO_GDS4058_16_mouse_BROWN ADIPOSE TISSUE GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.909132 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16983 GSE126345_7_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84141 LOUCY CCLE Cell Line Gene CNV Profiles -1.0 -2.69286 GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null liminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4067 r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18349 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07695 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOCS3_KO_GDS3149_8_mouse_multiple cell types GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07231 blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.447687 ATP5F1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95261 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE241701_2_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KLF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.7142 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6884 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72016 EGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70671 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00923 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 0.95807 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -1.40389 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5654_KD_FLI1_SRP117628 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.283 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.922023 TSNAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06715 NCAPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1152 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38819 RNF2-27304074-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null AK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19911 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4415 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29847 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87616 NCI-H810 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.251279 Nickel levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AR ChEA Transcription Factor Targets 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59369 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.67302 superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3031 hsa-miR-4706 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null apicolateral plasma membrane GO Cellular Component Annotations 2015 1.0 null choroid coloboma HPO Gene-Disease Associations 1.0 null r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25698 CEBPB_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NIHOVCAR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.52466 RAD21 ChEA Transcription Factor Targets 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lens disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.769 Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Galactokinase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.704 GSE213650_0_v_1_everolimus_human RummaGEO Drug Perturbation Signatures -1.0 null PHLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67196 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12701 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06075 HCC2279 CCLE Cell Line Gene CNV Profiles 1.0 1.49736 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947191 Lung adenocarcinoma_LUAD_TCGA-50-8459-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87422 HUT78 CCLE Cell Line Gene CNV Profiles -1.0 -1.64007 IPO7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03271 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCN4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18705 EIF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19318 HNF4A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.194 mantle zone of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0761 NCIH2347 CCLE Cell Line Gene CNV Profiles -1.0 -1.76234 DA-49-ZD74_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.220013 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32857 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null related GeneRIF Biological Term Annotations 1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Apical part of cell COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50864 KLF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 129.035 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Eye TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.713198 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BOD1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65882 HEATR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21724 CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06386 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parabrachial nucleus, lateral division, superior lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3061 periventricular stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3734 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127790_9_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5640_KD_JQ1_SRP142503 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.305 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14947 ARNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32614 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE178907_4_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null p1 part of the substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68024 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08221 RBMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59716 YY1 ChEA Transcription Factor Targets 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0782 Fields of Forel Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69721 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YAP1-20516196-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HERPUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25873 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02559 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100354_PCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.43141 mantle zone of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10859 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20409 SMC3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00191 IDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42869 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80621 CAL78 CCLE Cell Line Gene CNV Profiles -1.0 -1.74019 Perturb_5660_KO_ID2_SRP336141 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.84083 retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.065435 all HPO Gene-Disease Associations 1.0 null stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.594451 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST JASPAR Predicted Human Transcription Factor Targets 2025 1.0 74.6664 Medial entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.707 Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73269 CTCF MotifMap Predicted Transcription Factor Targets 1.0 null PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30604 AR-22383394-PROSTATE-CANCER-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Alcohol consumption (drinks per week) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 iris coloboma HPO Gene-Disease Associations 1.0 null GSE232631_0_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE205976,GSE205978_2_v_5_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null abnormality of the posterior segment of the eye HPO Gene-Disease Associations 1.0 null CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CIBAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02099 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.62606 H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE60691_0_v_3_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963506 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.975895 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04022 Pterygium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.539 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67598 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2174 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LC1F CCLE Cell Line Gene CNV Profiles 1.0 1.65698 ATF3 ENCODE Transcription Factor Targets 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157050,GSE157051_2_v_4_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null STAT3-24763339-IMN-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null JARID2 ChEA Transcription Factor Targets 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Wolfram syndrome 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.369 dorsal part of m1A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17318 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TET1 ChEA Transcription Factor Targets 1.0 null C10orf95 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34634 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.85157 H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10617 Perturb_5658_KO_SA2_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08218 YY1-22570637-MALME-3M-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 abnormality of the iris HPO Gene-Disease Associations 1.0 null Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05319 mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22658 medial portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.939063 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 MAP1S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14979 USF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDKN2AIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04549 CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.9239 External ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.966 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.692697 p1 part of the substantia nigra reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61025 intermediate stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2774 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.995129 RPL37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13134 GSE115542_2_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71014 inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.444115 Pituitary GTEx Tissue Gene Expression Profiles 2023 1.0 6.98697 NAGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1076 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4447 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYO1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61887 RXRA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR Rummagene Transcription Factor Associations 2026 1.0 null plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389289 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cholelithiasis DisGeNET Gene-Disease Associations 1.0 null Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.3255 MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10653 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 Aniridia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.539 ST6GAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19311 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.93236 H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25698 PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null r10 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28941 Nance-Horan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.864 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077101 JUN_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.988459 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76485 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J1-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.27943 HMGN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72818 intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03804 ELF1 ENCODE Transcription Factor Targets 1.0 null GNL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72556 H3K27me3_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COPS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76905 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33151 filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.604904 H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.549 ARPC1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0475 MTF2 ChEA Transcription Factor Targets 1.0 null Myofibrillar myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-GeneExpression_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null gamma GeneRIF Biological Term Annotations 1.0 null Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00235 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12088 coloboma HPO Gene-Disease Associations 1.0 null Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01434 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.8478 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.131714 intermediate stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17674 EFCAB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89897 GATA1 ENCODE Transcription Factor Targets 1.0 null preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.60102 lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70767 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE122215,GSE122217_5_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.894548 HCFC1 ENCODE Transcription Factor Targets 1.0 null TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.1571 Perturb_5664_KD_EWSFLI1_SRP339581 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.09133 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.5245 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5561 TOP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22237 CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56319 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00886 SYT13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46403 Diabetes Mellitus HuGE Navigator Gene-Phenotype Associations 1.0 null Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 57.5141 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29913 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26951 ATF3-27146783-CHIP-SEQ-COLON-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21646 GSE135030_8_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60394 Perturb_15107_KD_EWSR1_SRP169096 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.57474 PMC10290283-biol-2022-0622-sm3.pdf-492-FOXI2_FOXI2 Rummagene Transcription Factor Associations 2026 1.0 null Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11682 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.239007 HSPA12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37425 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NF-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 deep white layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08299 Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.20038 H2BK15ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE120612_6_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.875 SRY ChEA Transcription Factor Targets 1.0 null GSE60691_2_v_3_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.883421 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Coloboma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 GSE135030_3_v_10_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE86507,GSE86509_0_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null KLF17 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.9874 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.5155 Cognitive decline (age-related) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27444 DES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24595 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_530_KD_KLF15_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.76108 Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11661 LYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23891 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0479 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886907 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.01162 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_JARID2_20075857 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ZNF460 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 121.043 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.6197 intermediate stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28987 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null formation GeneRIF Biological Term Annotations 1.0 null Perturb_17325_KO_Dis3l2_SRP322105 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.00377 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.52612 retromammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43765 PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR Rummagene Transcription Factor Associations 2026 1.0 null abnormality of the anterior segment of the eye HPO Gene-Disease Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.564 raphe nuclei of medulla Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.865204 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2556 CAL33 CCLE Cell Line Gene CNV Profiles 1.0 1.33776 CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03197 r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65879 GSE115542_5_v_4_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null ASPC1 CCLE Cell Line Gene CNV Profiles 1.0 1.64039 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23688 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01768 RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1437 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5266 Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10859 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948411 496100335_PCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.19106 CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11757 NARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7885 USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Iris disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.352 CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.31902 ACHN CCLE Cell Line Gene CNV Profiles 1.0 1.55714 PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.63846 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07494 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20 Rummagene Transcription Factor Associations 2026 1.0 null PRPF40A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1541 Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2348 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877631 VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877322 H2AC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00805 substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.35443 Galactosemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.208 LUDLU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.32204 GSE63048_11_v_12_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54007 TET1-21451524-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19761 inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11384 Parabrachial nucleus, medial division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07307 superficial stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65579 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.717635 Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsomedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22485 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A689-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96734 RBBP5 ENCODE Transcription Factor Targets 1.0 null TXNIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65238 CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15565 intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.110817 intermediate stratum of r2BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29717 r4 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21005 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50994 CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09076 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75237 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31571 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01651 CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37153 glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.330295 microphthalmia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.06522 OAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25221 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14947 THOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49087 WDR48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42549 TATDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22374 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050935 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02366 GSE135030_3_v_9_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09507 EYA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03561 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAD21_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.259929 MFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72398 ZNF384 ENCODE Transcription Factor Targets 1.0 null CEBPB_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null closely GeneRIF Biological Term Annotations 1.0 null HEC50B CCLE Cell Line Gene CNV Profiles 1.0 1.78414 Cataract 11 multiple types DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.92 HDAC2 ENCODE Transcription Factor Targets 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27738 H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-96 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00836 subcuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01728 CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18398 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.42649 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PRKRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16283 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC0327 CCLE Cell Line Gene CNV Profiles -1.0 -1.36284 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lens TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.841608 mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.69493 PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100379_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17294 RGS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16398 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23833 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02557 Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.649 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60145 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_545_KD_CT_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.1666 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03277 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26469 intermediate stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29912 BRI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44594 KARPAS299 CCLE Cell Line Gene CNV Profiles 1.0 2.01828 Blood Pressure dbGAP Gene-Trait Associations 1.0 0.062132 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040908 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12013 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15904 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.8715 emx2_20962046_e10dot5_urogenital_epithelium_lof_mouse_gpl1261_gds3173 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.83938 Lens epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.382 PKN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1893 periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34147 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5656_KD_CT_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.04695 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null demonstrate GeneRIF Biological Term Annotations 1.0 null ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00937 abnormality of the fundus HPO Gene-Disease Associations 1.0 null Corneal edema DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29894 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5421 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13621 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.909132 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Stickler syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.039 ZNF501 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01097 Orbital area, ventrolateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03075 Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 100.861 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10895 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5630_KD_EWSFLI1_SRP340258 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.51127 Perturb_531_KD_NKX22_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.9547 plasma membrane region GO Cellular Component Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.53921 ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null ZBED4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 129.503 SIN3A ENCODE Transcription Factor Targets 1.0 null r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08375 ZNF449 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.6651 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41977 Lung adenocarcinoma_LUAD_TCGA-55-6979-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VAMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31868 CBX2-27304074-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18509 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.145 USF1 ENCODE Transcription Factor Targets 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE213632_1_v_5_acod1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51739 496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63519 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.00513 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877631 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10896 membrane GO Cellular Component Annotations 2015 1.0 null Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF888 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71679 Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1723 CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893063 Renal tubular transport disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.284 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08022 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27794 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.97001 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08065 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A704 CCLE Cell Line Gene CNV Profiles 1.0 1.53123 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90271 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3819 tmem235 GeneRIF Biological Term Annotations 1.0 null MOLM16 CCLE Cell Line Gene CNV Profiles -1.0 -1.54121 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Perturb_5633_KD_BRD4_SRP142503 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.45203 Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2639 Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16981 RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5632_KD_JQ1_SRP142503 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.212 lateral hypothalamic area, anterior region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38304 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50362 PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.97713 Perturb_546_KD_EF1_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 JMSU1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 RTL8C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1215 E2F8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4271 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13739 Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 CHD2 ENCODE Transcription Factor Targets 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60419 ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3972 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1 ChEA Transcription Factor Targets 1.0 null Phosphomannomutase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.479 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840465 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32857 Subgeniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20511 Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04443 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZC3H13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13866 GSE168807_6_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39171 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE224556,GSE224557_6_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1-25302145-T-LYMPHOCYTE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3098 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null basal nucleus of meynert, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54211 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1046 RTN4R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55911 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.358 TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ovum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975159 SMARCA4 ChEA Transcription Factor Targets 1.0 null SNAI2_01_225 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 9.85785 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null APLN_KO_GDS3228_601_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCIY CCLE Cell Line Gene CNV Profiles 1.0 1.39743 GSE188869,GSE188871_2_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null Medial habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE115542_5_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRPF38B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62085 Cataract DisGeNET Gene-Disease Associations 1.0 null FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 76.8792 Adventurousness GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.887387 ventral paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10697 Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal eye morphology HPO Gene-Disease Associations 1.0 null lateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0761 Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15468 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210885_0_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10653 Lung adenocarcinoma_LUAD_TCGA-55-6980-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_547_KO_SA1_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.18201 TBX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71099 STAT3-18555785-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null apical plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 SOCS3_KO_GDS3149_297_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837411 MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2181 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CDCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39502 CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27936 abnormality of the globe HPO Gene-Disease Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.00547 H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEPG2 CCLE Cell Line Gene CNV Profiles 1.0 1.7775 Lens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.724 SOX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74141 ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23355 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SARS-CoV_0Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.45023 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66563 MXI1 ENCODE Transcription Factor Targets 1.0 null frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.85164 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DCTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.84371 MCM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05066 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12312 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Parabrachial nucleus, medial division, external medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16168 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null channel GeneRIF Biological Term Annotations 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54642 CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82758 periventricular stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40716 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null CENPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72022 CTBP2-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF148 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 150.779 periventricular stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09447 496100555_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.54633 KDM4C_natural variation_GSE41040_588_human_fibroblasts fron neonatal foreskin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PLPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02244 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86683 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null eye TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTF2H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42045 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.762 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KCNK17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23422 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pretectal nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09376 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14798 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5621 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.87596 HMGB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80898 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null ChIP_MTF2_20144788 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null mammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43238 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100431_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.52955 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.909866 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR Rummagene Transcription Factor Associations 2026 1.0 null Chronotype GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16848 ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51022 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62P-01A-32R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLGAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18473 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888298 pituitary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.857643 ETS1 ENCODE Transcription Factor Targets 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autoimmune thyroiditis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 CEBPB_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27206 PCLAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09126 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57883 CHD7 ENCODE Transcription Factor Targets 1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8747 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34513 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral IC periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07536 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A8BX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH810 CCLE Cell Line Gene CNV Profiles 1.0 2.55063 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65763 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15216 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.398962 TOP2B-26459242-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8749 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PL-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948411 Cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.663 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14138 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.874346 CTCF_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null reproductive system phenotype MGI Mouse Phenotype Associations 2023 1.0 null Lens cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.855 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19298 mantle zone of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25736 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.09538 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.72891 planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.842588 Gigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01889 AUTS2-25519132-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0159 lens disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.27911 Apical plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CAMK2G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87096 DANG CCLE Cell Line Gene CNV Profiles 1.0 1.40804 PABPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08699 H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14613 TMEM249 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92875 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888298 H4K91ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Axenfeld-Rieger syndrome type 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.659 intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67112 mantle zone of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43765 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS27 CCLE Cell Line Gene CNV Profiles -1.0 -2.79724 Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05784 MSH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38963 NCIH1693 CCLE Cell Line Gene CNV Profiles 1.0 1.92708 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100315_TCx_no dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65922 JARID2-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100592_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.78463 STAT3-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157929 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12941 GATA3-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0388 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75706 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862799 CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null voltage GeneRIF Biological Term Annotations 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34117 HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.80721 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.76199 Plasma membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26681 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4798 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.50637 PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04324 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.7619 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the eye HPO Gene-Disease Associations 1.0 null H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70643 HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.45983 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fetal Lung Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.39029 SUZ12-16625203-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE107505_0_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.0019 496100456_TCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42406 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.448346 PARD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73163 GSE199606_5_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE127790_13_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50948 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78188 GSE115542_2_v_4_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null RBP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3048 SFXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0501 NCIH2141 CCLE Cell Line Gene CNV Profiles 1.0 2.25511 Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40388 Perturb_1834_KO_Ogt_SRP250299 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RING1B-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86683 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88324 Glaucoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 DKMG CCLE Cell Line Gene CNV Profiles -1.0 -2.16343 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53069 Lens epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.735 LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 PMC11202056__F8 PFOCR Pathway Figure Associations 2024 1.0 null nucleus incertus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24553 MYC ENCODE Transcription Factor Targets 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.17894 H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3036 ZNF573 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22942 lateral part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02023 mantle zone of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14661 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06386 Hmgn1_KO_GDS5010_405_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30185 TMEM140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57333 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ChIP_SUZ12_16625203 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Habenular trigone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE160246_0_v_1_cpeb4_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMARCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10765 ATXN7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0299 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null furan CTD Gene-Chemical Interactions 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6009 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Childhood type dermatomyositis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 aplasia/hypoplasia affecting the eye HPO Gene-Disease Associations 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null sirolimus_homo sapiens_gpl2895_gse16944 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.61011 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Anterior segment dysgenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.625 KLF1 ChEA Transcription Factor Targets 1.0 null CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19902 Perturb_5569_KD_SIX2_SRP254559 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 DEDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10432 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34147 smooth muscle HPA Tissue Protein Expression Profiles 1.0 1.17617 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2135 hyperferritinemia-cataract syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.863 Orbital area, lateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10371 anterodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.968393 USF2 ENCODE Transcription Factor Targets 1.0 null RAD21_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02559 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199606_5_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 TBP ENCODE Transcription Factor Targets 1.0 null P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10522 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73361 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.893875 USF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10859 MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Peters anomaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.282 Principal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.72 r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12145 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28457 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.5559 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28214 PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_16_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal motor nucleus of the vagus nerve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17832 TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.42023 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27794 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893063 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.258 ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24553 Perturb_5655_KO_STAG2_SRP151746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.38785 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41751 RAD21-21589869-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESCRT III complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.879 HT1376 CCLE Cell Line Gene CNV Profiles 1.0 2.07567 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06528 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127790_5_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null retinal coloboma HPO Gene-Disease Associations 1.0 null NUP153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7736 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endoplasmic reticulum LOCATE Predicted Protein Localization Annotations 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAP29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44655 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.863165 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06528 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM106A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18725 CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE213650_0_v_2_everolimus_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72712 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.27753 ALKAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80256 Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A3OU-01A-31R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42082 H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4579 superficial stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42811 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9191 CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.45362 Sublaterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0784 H2AFZ ENCODE Transcription Factor Targets 1.0 null Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.634 PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77724 CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM174C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30264 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054962 family GeneRIF Biological Term Annotations 1.0 null CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02559 Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9833 periventricular stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0769 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Renal tubule epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.554 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948411 intermediate stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34479 superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78 RNF2-27304074-CHIP-SEQ-NSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_541_OE_EWS/FLI_SRP168620 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.81492 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100479_FWM_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.21763 CEBPB_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8330021-13058_2021_1455_MOESM8_ESM.xlsx-MSC_HEATMAP-Unnamed_0_MSC Rummagene Transcription Factor Associations 2026 1.0 null membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.182422 OSR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7613 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.8036 WDR91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.02898 BIRC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08755 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.954237 Lens nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.055 GATA3-21867929-TH1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59472 RCOR1 ENCODE Transcription Factor Targets 1.0 null NDUFB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47722 FOXA2 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.356705 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10653 perifornical nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00601 m2 part of substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.93878 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.99628 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13393 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autoimmune disease of endocrine system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2 Rummagene Transcription Factor Associations 2026 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25409 CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.3137 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6136 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A772-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221061 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39997 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.27955 DCAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57585 CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.58324 Supramammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64027 GSE113817_0_v_1_bach1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_555_KD_PHF2_SRP277893 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.2218 BRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05357 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.44818 ZRANB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54555 RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chorioretinal coloboma HPO Gene-Disease Associations 1.0 null 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11766 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intracranial aneurysm GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960274 GSE173873_1_v_3_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mammalian GeneRIF Biological Term Annotations 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24943 Type 2 diabetes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13577 Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42158 EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNAPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36092 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053155 mantle zone of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17318 Cataract 32 multiple types DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.001 Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACOT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34843 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.98751 sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE122215,GSE122217_0_v_4_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-1271 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ST-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.909 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07827 intermediate stratum of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21095 NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 65.368 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE247084,GSE247087_0_v_1_cdyl_human RummaGEO Gene Perturbation Signatures -1.0 null mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null EXD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51924 CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null globe disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.717232 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null XPO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01347 Posterior polar cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.095 intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7368 TAF1 ENCODE Transcription Factor Targets 1.0 null ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null PRNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38449 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1195 CCLE Cell Line Gene CNV Profiles 1.0 2.31142 CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145915_3_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03413 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.03925 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044436 Cholecystolithiasis DisGeNET Gene-Disease Associations 1.0 null mantle zone of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17052 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.890507 Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37996 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36695 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.952848 r2 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25409 intermediate stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33656 Lateral entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.738 SMAD2/3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLA2G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08561 GSE146156_2_v_3_tagap_mouse RummaGEO Gene Perturbation Signatures -1.0 null temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06566 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null lens epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.978917 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05537 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28434 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0609 PMP-22/EMP/MP20/Claudin superfamily InterPro Predicted Protein Domain Annotations 1.0 null phycobiont TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.604502 OLIG2-26023283-AINV15-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.752 USP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29235 Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28646 Renal glycosuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.011 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE193588_1_v_0_pax3_mouse RummaGEO Gene Perturbation Signatures 1.0 null cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.62885 CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2737 CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACSBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83241 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.894507 GSE157050,GSE157051_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78P-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retromammillary area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33553 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.142141 VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04926 MAZ ENCODE Transcription Factor Targets 1.0 null MRPL20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65801 Perturb_1975_KO_Ogt_SRP250299 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 KLHL17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38064 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null LSM12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35001 BHLHE40 ENCODE Transcription Factor Targets 1.0 null layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00886 epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4487 MOSPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1224 Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.76098 Habenular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.674 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substantia nigra compacta, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35594 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18509 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87218 Lens TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06906 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.3308 abnormality of the uvea HPO Gene-Disease Associations 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null phenotypic abnormality HPO Gene-Disease Associations 1.0 null Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44395 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08221 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07231 NCI-H1155 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.617 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17585 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.49691 medial parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34273 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7529 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2642 H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21734 testis HPA Tissue Protein Expression Profiles 1.0 0.724977 b69 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.235 APH1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02895 Axenfeld-Rieger syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 PLEKHH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5711 STMN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10275 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null H4C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17355 GSE143847_2_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96183 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958879 Intramolecular phosphotransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.479 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2405 CCLE Cell Line Gene CNV Profiles 1.0 1.45414 Perturb_5661_KO_ID2_SRP336141 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51022 Senile cataract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10522 SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null EJM CCLE Cell Line Gene CNV Profiles 1.0 1.84985 SIRT3_KO_GDS4058_454_mouse_BROWN ADIPOSE TISSUE GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.845116 PIGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77893 Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043583 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chorioretinal abnormality HPO Gene-Disease Associations 1.0 null liminal part of the r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25782 Septal area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.714 TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36645 H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR3D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.91454 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MNX1-26342078-MIN6-4N-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.0756 GSE249098_1_v_2_mthfd1l_human RummaGEO Gene Perturbation Signatures 1.0 null LANCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15569 Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41182 JUN_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948411 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17899 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842204 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22852 periventricular stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1226 periventricular stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14518 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37064 GSE239578_0_v_6_cxadr_mouse RummaGEO Gene Perturbation Signatures -1.0 null NDUFA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81253 membrane region GO Cellular Component Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947191 REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Vital Capacity DisGeNET Gene-Phenotype Associations 1.0 null GRWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41109 Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05274 GSE205976,GSE205978_3_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70707 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66248 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3185 CA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22418 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.33163 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ZNF282 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8161 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FXR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48405 GSE210885_5_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21525 NCIH1048 CCLE Cell Line Gene CNV Profiles -1.0 -2.2696 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895628 dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.74104 GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cuneiform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.983715 lateral part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17498 ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69973 membrane part GO Cellular Component Annotations 2015 1.0 null central gray substance of midbrain, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969414 KASUMI1 CCLE Cell Line Gene CNV Profiles -1.0 -1.88277 PTCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36076 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02559 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02559 r10 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83728 USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3479_KO_Mcph1_SRP401970 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.67005 r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57751 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gap junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.896 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35013 dependent GeneRIF Biological Term Annotations 1.0 null fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314409 hsa-miR-4683 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE201239_6_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUBB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46571 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.68572 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46947 PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null apical part of cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5294 GSE235596_0_v_1_pikfyve_mouse RummaGEO Gene Perturbation Signatures 1.0 null substantia nigra compacta, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54089 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.902892 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.176024 CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01332 SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -2.02038 CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15904 calcium GeneRIF Biological Term Annotations 1.0 null CHMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23912 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06625 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.1467 isthmus proper Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02769 ARID3A ENCODE Transcription Factor Targets 1.0 null intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70707 CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIPRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85972 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18509 ZNF862 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50297 SLBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12062 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.893063 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.285316 METTL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1077 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968528 RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ING3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02213 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 ALG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64317 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217974 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63538 PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07443 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55743 dorsolateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10048 r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22051 Kna TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.802 GSE197686,GSE197688_2_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33983 SOX9-26525672-CHIP-SEQ-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39499 SUZ12-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CDC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40484 Perturb_552_KD_EWSR1/EWSR1FLI1_SRP273158 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.7749 ZNF213 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.0844 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81568 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JARID2-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null IL17RB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09518 CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50752 GFI1_KO_GDS4204_147_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960274 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88895 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03341 gyrus rectus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0719 ACAD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03574 SDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16979 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null HLE-B3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.148 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54323 PRIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16406 CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76551 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8485 GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null 496100468_PCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.70235 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.008629 Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16701 JUN ENCODE Transcription Factor Targets 1.0 null apical plasma membrane GO Cellular Component Annotations 2015 1.0 null GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29717 Uveal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.043 CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1961 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29868 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.60436 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06204 GATA2 ChEA Transcription Factor Targets 1.0 null apicolateral plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null frontal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.910582 Optic atrophy 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.3816 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9181 ZNF831 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03744 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.76711 Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area, ventrolateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02186 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10653 Gall bladder epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.606 mantle zone of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02023 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60199 KLF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22028 ACIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36991 HRH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13004 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3741 H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56228 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE211286_1_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null EBF1 ENCODE Transcription Factor Targets 1.0 null tmem114 GeneRIF Biological Term Annotations 1.0 null SPHK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.686 SAP30 ENCODE Transcription Factor Targets 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13005 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_537_KD_MYBL2_SRP161768 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Rectum adenocarcinoma_READ_TCGA-DC-6683-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932455 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null HNF4G JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9057 VASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72807 ChIP_SUZ12_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE86507,GSE86509_0_v_1_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.300682 dorsolateral TG part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41855 GATA1-19941827-MEL-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06386 CANX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23596 abnormality of the choroid HPO Gene-Disease Associations 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1 MotifMap Predicted Transcription Factor Targets 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74272 Wolfram syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.13 Perturb_14225_KO_Tcf12_SRP392331 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.33765 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13042 RFX5 ENCODE Transcription Factor Targets 1.0 null CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06386 JAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16874 RAD21_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SMNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12947 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050935 Deprivation amblyopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 Microphthalmia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.867 PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Subceruleus nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06531 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6897 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null members GeneRIF Biological Term Annotations 1.0 null ZNF135 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.4124 YAP1 ChEA Transcription Factor Targets 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.918341 GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.958879 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lens TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888298 CEBPB_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.99156 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100574_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28447 STAT1 ENCODE Transcription Factor Targets 1.0 null TLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66118 ATF3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 YY1-22570637-MALME-3M-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22564 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2BK20ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DPCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10621 Medullary reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33684 RPP25L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5441 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100500_PCx_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.64564 CAKI2 CCLE Cell Line Gene CNV Profiles 1.0 1.55622 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.39211 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.33163 VCAP CCLE Cell Line Gene CNV Profiles -1.0 -1.6235 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CAPZB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50344 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16054 PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF Rummagene Transcription Factor Associations 2026 1.0 null Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.556 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.83968 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.9541 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205976,GSE205978_2_v_4_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null REST ChEA Transcription Factor Targets 1.0 null ZNF524 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2386 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29175 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100390_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23387 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null SACM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15189 H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73982 HINFP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9278 MAFK ENCODE Transcription Factor Targets 1.0 null plasma membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.007697 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Cortical collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.661 KP3 CCLE Cell Line Gene CNV Profiles 1.0 1.35298 USP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73945 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46093 ETS1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46351 WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5621 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11661 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPB_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.40764 CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09397 EZH2_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935581 PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.881242 Congenital Cataract DisGeNET Gene-Disease Associations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10751 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FAM234A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54867 MRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63443 H3K4me1_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PRPF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3625 CTCF_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.36369 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8765 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE122215,GSE122217_5_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null cataract GeneRIF Biological Term Annotations 1.0 null EVPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15378 TAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47461 USP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05165 SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null subunit GeneRIF Biological Term Annotations 1.0 null navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0682 GLIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.4269 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886907 RAD21 ENCODE Transcription Factor Targets 1.0 null abnormality of the retina HPO Gene-Disease Associations 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.41613 respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HPBALL CCLE Cell Line Gene CNV Profiles -1.0 -2.13581 GSE152050,GSE152052_1_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02691 PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Tfcp2l1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.6992 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69471 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EIF4G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1064 Midbrain reticular nucleus, retrorubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7729 POP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30632 MZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.6831 TT2609C02 CCLE Cell Line Gene CNV Profiles -1.0 -1.65715 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86008 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1531 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.947191 496100611_FWM_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.58962 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -6.15339 Perturb_5659_KO_SA2_SRP201842 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2345 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE86507,GSE86509_4_v_1_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null AFG3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06256 CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Primary visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01728 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17282_KO_Hsf5_SRP345601 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.8576 superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.35443 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37112 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lens fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.854 FOXA1_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NADSYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28437 WDR13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27299 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null periventricular stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07231 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXD4L6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02358 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2266 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LC1SQSF CCLE Cell Line Gene CNV Profiles 1.0 1.34699 mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.907216 CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null triangular septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06456 NRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10382 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ICAM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18447 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975159 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6691 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IC-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Posterior hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.974 TEAD4 ENCODE Transcription Factor Targets 1.0 null TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2546 CHST15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03994 r10 part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37248 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23802 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GDAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57156 PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null GLIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.9139 episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12941 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041428 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.975159 CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13233 lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01522 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23655 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.09433 cellular_component GO Cellular Component Annotations 2015 1.0 null PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-ENSEMBL_AR Rummagene Transcription Factor Associations 2026 1.0 null Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04606 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null P68-20966046-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6366 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63W-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF619 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15193 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rhombomere 10 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08336 CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA4-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.356705 DDX60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29904 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null Sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_5653_KD_EWSR1_SRP117628 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.39165 GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59615 ATF3_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null cochlear nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0311 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872986 PAFAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82456 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41P-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERGIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13886 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB361 CCLE Cell Line Gene CNV Profiles 1.0 1.47592 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZBTB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00786 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RNF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52634 LAGE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66501 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ILK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59819 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Parabrachial nucleus, lateral division, central lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28337 ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.8381 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDCK-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.992 r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30407 CTCF_SK-N-SH_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13068 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96403 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TM6SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65668 isthmic part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07307 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66936 RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.9185 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CORL24 CCLE Cell Line Gene CNV Profiles -1.0 -1.4228 FOXA1 ENCODE Transcription Factor Targets 1.0 null 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86658 Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35539 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4472 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 r2 part of nucleus subcoeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47266 Takayasu arteritis GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02236 CPSF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1067 Glucosidase II complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.953 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7274 496100570_HIP_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.73064 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45823 r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16795