association	dataset	threshold value	standardized value
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33043
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76835
ZNF417	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95296
GSE126402_1_v_6_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67131822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08021
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroquinine-2767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923808
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261613
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218714
asiaticoside-3504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43258
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31965
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916228
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14000735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21279
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422845
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837729
BRD-K60272064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06247
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-dep_3dpt-SYMBOL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3206
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Plant crown	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94685203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63476
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.874415
Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74624
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.88728
valinomycin-5957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6734_KO_TOP3B_SRP345494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.44
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49854
GSE60691_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
acacetin-6044	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
5155877-6574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986274
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38286
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.24632
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08518
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880703
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19528
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.539973
BRD-K69668687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08689
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24839
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	5.90547
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.93792
GSE134608,GSE134609_2_v_6_dlx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82511
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Down_REST	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34620971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15005
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05761
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7863
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824785
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304047
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58817
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20109
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74029
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61709
COLO205	DepMap CRISPR Gene Dependency	1.0	2.19108
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.975081
BRD-K28746174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42472
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32504
MYC	ChEA Transcription Factor Targets	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74273
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22758
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21666
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.939518
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92202681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8421
BRD-A08820802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36662
OPM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61282
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918739
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bestrophinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77648
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77480803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12288
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroquinine-5789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SELENOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72902
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
BRD-K59667434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31628
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12267335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33196
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64543
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74826740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22821
6-bromoindirubin-3'-oxime-7106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESC_J1_UP_EARLY.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76395
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30373
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908426
gcc	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07855097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55838
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923381
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15489
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.28112
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98936
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826806
BRD-A64153357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21351
EHMT2_KD_GSE34925_693_human_MDA-MB231 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878537
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900653
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.27782
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08165
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041461
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13927197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75105
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7044
PMC3435504-msb201237-s2.xls-Supp_Table_4a-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900531
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845938
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05982
BRD-K83547183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85105
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67156
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5731
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47503
arcaine-4974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.874415
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.70535
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
BRD-K13016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05662
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26581
BRD-K41762421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0624
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843227
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55932
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51184
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00035
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40345
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94194
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75638
GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
molecular_function	GO Molecular Function Annotations 2015	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07859
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04404
BRD-K71194915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56281
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14291
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55866
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897911
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29646
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23941
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9446
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03952
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12543
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970744
BRD-K08974502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39738
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40128
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27643
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.35373
BRD-K03287885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.121
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0821
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
BRD-K61621331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32897
BRD-K37203382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35633
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260477
BRD-K87901124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84981
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44305
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20808
BRD-K55916310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96478
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962461
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15322
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.698309
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80559
BRD-K19699893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12967
interleukin-15 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
CTCFL	ENCODE Transcription Factor Targets	1.0	null
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14115
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17155
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85023
SMC3	ENCODE Transcription Factor Targets	1.0	null
disopyramide-7276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNPPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52577
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843095
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	2.76402
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51608
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32165
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
NCIH1703	CCLE Cell Line Gene Expression Profiles	1.0	1.57959
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7582
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.6833
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82714
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8799
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27938
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14538
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
fursultiamine-6630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53669
felodipine-6695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20181
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.844119
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13106
PDE7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91809
MXI1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
conessine-2792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02128
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17894
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
thalidomide-2258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864851
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4601
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.1129
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.30748
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5612
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.61982
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08287
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42097
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18095
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16727
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11029
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	2.00195
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-123	GDSC Cell Line Gene Expression Profiles	-1.0	-2.37862
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09613
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66496
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79407655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00968
carteolol-4176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13139
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89976
daunorubicin-7511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12662
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26852
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
progesterone-6646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92194
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5345
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98978
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462875
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07432
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3433
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04953
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942516
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02813
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prazosin-5416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64366
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.137333
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52896
CMK	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45623
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	3.91905
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prestwick-857-4980	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848417
BRD-K88437756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38215
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
flucytosine-6450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2681
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38236
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30524
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36652
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649305
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96663576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87309
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41745
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962888
COV644	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82268
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31836
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81217407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18695
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.71321
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02416
ARL5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03287
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996578
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.85957
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08297
BRD-K53401077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1036
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47378
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44833533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36615
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33508
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
BRD-K02133388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38472
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440267
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882323
fulvestrant-5565	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02031
BRD-A96183603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0969
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15326
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.21715
noscapine-5851	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01912
hsa-miR-3180	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9993
TTLL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39699
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71537757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17854
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42567
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.876414
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06567
adiphenine-7037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39282
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824672
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.636665
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1099
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K06177900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07301
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27872
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92869
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230311
Prestwick-1082-7267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40253
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70217
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317844
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217486
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BRD-K05605336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79312
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967024
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33041
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14222
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00003
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19923
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06883
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16833
YBX3_02_98	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.53797
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6779
19204204-SupplementaryTable5	GeneSigDB Published Gene Signatures	1.0	null
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45586
BRD-A43164341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03918
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.34127
testosterone-5636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K39962926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6684
glibenclamide-3163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11942
superior parietal lobule, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910617
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66153
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90705
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11063
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870265
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35967
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85605
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
(-)-isoprenaline-6833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3313
helveticoside-4327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51222
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07141
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09908
GPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11185
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09549
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99052
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91165
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30146
A2780	CCLE Cell Line Gene Expression Profiles	1.0	1.7263
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.465
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2144
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19038
metacycline-7321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K19033697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20156
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
nipecotic acid-5999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11598
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76496
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33561
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285667
NB10	DepMap CRISPR Gene Dependency	1.0	3.6654
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25068
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09267
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.502
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985796
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49704392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56933
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981961
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10439
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0645
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899167
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03278
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58796
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8231
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
mefexamide-2121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31082
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.17479
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0175
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858057
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18297
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64781
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879608
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14635
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.88281
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832194
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841164
Lung adenocarcinoma_LUAD_TCGA-55-8090-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30215
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17525
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33516
AD-54-IH37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244405
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298828
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71223
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26937
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
GRIK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49626
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00792
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57537
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890356
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1389
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09607752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89647
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97074
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76049
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gata4_21746915_heart_lof_mouse_gpl6246_gds3931	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.011578
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53374
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348142
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480127
BRD-K96778009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23436
BRD-K85909950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41339
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37482
calcium folinate-7401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE228413_4_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34003
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80094
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07111
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MES-SA	GDSC Cell Line Gene Expression Profiles	1.0	1.47673
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15836
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62092
tacrine-6698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52806
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.0449
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72947
EGFL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09144
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04634
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01534
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26779
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661547
KCTD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07083
BRD-K62226454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92631
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83771
dicloxacillin-3307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15512
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63678
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831369
SAFB2_02_102	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.48938
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42318
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7878
dextromethorphan-5401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EPHB2_drugactivation_228_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66649
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912281
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09871160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51696
monastrol-596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17231179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72525
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6823153-NIHMS1535502-supplement-3.xlsx-LSD1_SupplData1-Supplementary_Data_1_Potential_common_target_genes_of_LSD1_and_GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46612
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876343
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27915
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54215
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9402
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40128
co-dergocrine mesilate-4152	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289789
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910046
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7562
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09457
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01389
HCC1187	DepMap CRISPR Gene Dependency	1.0	6.77303
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7036
moroxydine-6705	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17063694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22314
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2558
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23617
thiamphenicol-7274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53062
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03375
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45267
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09996
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3-hydroxy-DL-kynurenine-4681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75112
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968414
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_37_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52444
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896305
CRCGN011_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4437
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39816
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.764
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11004
estropipate-6068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34408
JAR	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14267
STAT1	ENCODE Transcription Factor Targets	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.22436
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
phenelzine-4360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trioxysalen-6078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sirolimus-5567	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1753_KO_Stag2_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3058
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34437
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09197
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56599
BRD-K01973494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30421
BRD-K93310782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01482
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412397
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chinese	GeneRIF Biological Term Annotations	1.0	null
Prestwick-1082-7027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07547
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39854
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73429
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05796
BRD-K20073772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4551
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
USF1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30957
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2338
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9292
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
phenindione-5991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nmyc_OE_GDS2406_14_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44969
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0803
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873106
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960152
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14432
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43793
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04117
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33221810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28945
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848412
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1198
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_233_KD_BRG1_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938196
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19734
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934635
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4139
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19874
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271832
SLC4A1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99603
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55003
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
RUNX2_01_62	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.14938
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.128
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.7407
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42317
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genistein-5595	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23828
BRD-K83254798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96836
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94476572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12579
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824158
hsa-miR-548a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sulfasalazine-6346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70315
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882091
insertiondeletion	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE111102,GSE111105_3_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37783
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1579
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17615
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3500769-srep00875-s3.xls-AP1-Time_0_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21549
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
karakoline-4763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28621
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57943
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5142
BRD-K94205659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15621
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84653
levomepromazine-4723	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14166
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.895586
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257593
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1962
tremorine-3196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54711
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4228
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.132
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41505
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17354
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73071
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258315
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04294
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56932
BRD-K50400833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10272
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3267
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66833
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14851
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26612
tetrahydroalstonine-2748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980654
ZNF263	ENCODE Transcription Factor Targets	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.1761
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877958
Perturb_8778_KI_SMARCB1_SRP223162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.56862
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84321
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12346
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5565-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart Defects, Congenital	HuGE Navigator Gene-Phenotype Associations	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45785
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65833
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.80217
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2567
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853334
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05013
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827115
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11969
BB-93-VT73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313923
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70087673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68741
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43891
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25266
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43056
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5456
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00646
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57853
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54532
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41436
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930789
PMC10238271-41388_2023_2678_MOESM8_ESM.pdf-3-PAX5_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40945
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1120_KD_CCND3_SRP325057	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.29414
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48022
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3795
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26233
UBTF	ENCODE Transcription Factor Targets	1.0	null
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18135
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32055
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51996
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	4.21561
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925281
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87991
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31747
STK17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16897
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824464
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6312
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pronetalol-7322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29519734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29815
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71121
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28356
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424361
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02599
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974539
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987079
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34183
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947371
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839128
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61598
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08643
BRD-K31584969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13776
6-bromoindirubin-3'-oxime-6589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.975889
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390291
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2153
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76547
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60773
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930116
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982783
igg immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.54194
hexylcaine-5768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46738
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16355
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87438
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480625
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01023
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
BRD-K92349794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70752
BRD-K01723566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29237
BRD-K26863838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03629
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87281
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7018
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962934
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.871874
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12306
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10716174-41467_2023_43919_MOESM10_ESM.xlsx-top500_STAT1_ChIPseq_ENCSR000EZ-SYMBOL_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
velnacrine-6651	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87492
hsa-miR-4770	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0741
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05422
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7697
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4647
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872612
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19424
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73729
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.68968
BRD-K76115264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19059
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
Osteopoikilosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.949161
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
E2F6	ENCODE Transcription Factor Targets	1.0	null
cyclopenthiazide-7325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HSF1_KD_GDS1733_753_human_HeLa cells - 4 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC11216188-peerj-12-17616-s011.pdf-49-CENPB_CENPB	Rummagene Transcription Factor Associations 2026	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12237
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997974
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994888
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91353
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59717
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
ampicillin-1530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19225562-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90942
snp	GeneRIF Biological Term Annotations	1.0	null
procarbazine-5452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0043
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95316
KYM1	DepMap CRISPR Gene Dependency	1.0	4.27876
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04669
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459563
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89965
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.65
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76566
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39856
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.981539
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548f	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26356
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352336
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306074
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81502
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3996
Perturb_5571_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.75686
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45698
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269149
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methocarbamol-7467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amitriptyline-5453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66416
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.45828
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825658
VEZF1_02_179	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.53605
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33491
MGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80514
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47705
hexetidine-6319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25406
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839755
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7863
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26498
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.962877
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
latamoxef-4648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97541
metrifonate-5989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51014
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45699
hsa-miR-3185	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
PMC8530322-pone.0258316.s002.xlsx-GG_776_no-AA_776_no-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29771129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85577
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47915
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90928
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874661
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976357
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96088
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F3_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
OPM2	DepMap CRISPR Gene Dependency	1.0	6.19154
acepromazine-2769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43754
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955647
STAT5_01_279	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61051
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4E-Supplemental_Table_S4E_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_MCF-7_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70429
BRD-K29784863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41172
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03309
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71047
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09757
A427	GDSC Cell Line Gene Expression Profiles	1.0	1.86215
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959928
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
epitiostanol-4788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57491
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19829
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5849_OE_Nnmt_SRP173793	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12561
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8185
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12253
kanamycin-4625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13972
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15198
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64481
MEL-745A cl. DS19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
BRD-K49698948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30176
ursodeoxycholic acid-7243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444088
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11984
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05211
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881512
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29403
BRD-K27458941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29994
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49406
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36466
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73554
FLI1	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL34	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22762
apomorphine-6683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05625
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81487
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67924
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960933
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884699
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01123
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5393
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1133
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.78672
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.962251
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21405
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08765
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65869
congenital	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.831422
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2868
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.49032
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42479
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40476
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-924	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A69P-06A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85163
cinchonidine-2772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76093
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5002
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37691
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904057
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851724
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59844
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93052
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37045
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13231
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1754
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3293
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Plasmacytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ICC3	DepMap CRISPR Gene Dependency	1.0	3.79516
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25177
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.96986
BRD-K47906308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07305
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861937
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23974
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K55399138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54493
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422777
EWSR1_KD_GDS4962_467_human_not specified	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-Unnamed_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01991250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9477
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18156
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05621
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.10877
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.132
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438437
thalidomide-5990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Annular pancreas	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78825
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09419
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12574
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16488
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12929741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2951
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85847
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10358
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
securinine-6831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53463
BRD-K19800225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0621
LY-294002-1664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3989
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4333
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48384
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
chr14_105530256_G_C_b38	GTEx eQTL 2025	1.0	1.06318
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32446
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29549246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95483
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11089
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3605
PMC10915192-ab-23-0304-Supplementary-Table-S6.pdf-68-TCF3_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71007
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041714
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284041
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10095
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24724
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22744
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of FCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02995
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996407
cyproheptadine-1521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02387
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3500769-srep00875-s3.xls-AP1-Time_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997971
chlorambucil-4523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19722
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209486
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45934
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903218
BRD-K81447429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43041
colforsin-7104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
suxibuzone-6065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17421394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89079
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methazolamide-6268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71853
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
troglitazone-5229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
trichlormethiazide-4198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic gastrinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
GSE129465_3_v_2_phf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958752
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20221
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38346
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07329
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
levonorgestrel-4730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85398
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06162
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299496
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-dep_8dpt-SYMBOL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58888361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01408
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54334
vidarabine-3445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00777
BRD-K42558179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2935
SETDB1	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30258
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931242
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40472
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27683
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60358
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55862
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IgG N-glycosylation phenotypes (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.83979
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3383
etamsylate-7335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31393518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84408
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19097
EWSR1_KD_GDS4962_469_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
bcor_22012066_cn_aml_lof_human_gpl570_gds4280	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.053905
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.720886
moxisylyte-1804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
PMC3500769-srep00875-s3.xls-AP1-Time_4_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3027
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28852
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN18	CCLE Cell Line Gene CNV Profiles	1.0	2.08155
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.91193
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50498
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1157
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
isoconazole-2218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05706
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39413
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67593
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57514
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19088
BRD-K11117868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64617
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3180-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3352
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373207
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00675
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1704_KO_Arid1a_SRP182831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87148
BRD-K01360791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6924
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.52845
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94573433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10873
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14646
BRD-K61660466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23581
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27692586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14676
BRD-K17549032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51891
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15536
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6317
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
DNAJC2	ChEA Transcription Factor Targets	1.0	null
nordihydroguaiaretic acid-524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41332
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73832
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34437
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61822
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04271
BRD-K67177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57118
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90359063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02247
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950697
TCF12	ENCODE Transcription Factor Targets	1.0	null
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
isradipine-6347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40927
AG-028671-6557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24103
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299627
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.60988
WDR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99665
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76613
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
BRD-K57586808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4458
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35881
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9825
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19551
BRD-K04531886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36999
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0737
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32854
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18229
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00309
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847878
CBX2	ENCODE Transcription Factor Targets	1.0	null
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904544
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284186
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32139
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548g	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79802
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82028
desipramine-6693	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13404
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31157
ECHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1269
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8466
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29509
G402	CCLE Cell Line Gene Expression Profiles	1.0	1.98318
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.12943
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00272
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929392
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00159
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39571490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4923
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44329
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04271
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34007
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18004
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394171
BRD-K95111937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53888
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14931
BRD-K53768630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75879
BRD-K40306365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19546
hsa-miR-1323	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88738
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04147
Perturb_1754_KO_Stag2/Runx1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.760534
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8101
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05842
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83814
tilmicosin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68565
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21023
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10069
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15432
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30013
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23234
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949346
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.4685
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01023
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30131
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.8085
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2021
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.761671
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45703
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
U87MG	DepMap CRISPR Gene Dependency	1.0	2.96343
BRD-K36095954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11042
KASUMI2	CCLE Cell Line Gene Expression Profiles	1.0	1.75887
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886087
baclofen-6313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61511
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19582
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05222
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03386
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79061
RBM14_02_03	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.80735
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58987
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00559
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32055
RUNX1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28209
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285167
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.882672
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54688
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853335
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clofilium tosylate-6830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49011
BRD-K05253426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72263
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86285108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43709
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849484
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BRD-K96510191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50516
mantle zone of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38662
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14166
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14432
OCIMY5	DepMap CRISPR Gene Dependency	1.0	9.16158
RCHACV	CCLE Cell Line Gene Expression Profiles	1.0	1.49007
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906548
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6714
JUN	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30939
torasemide-3517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46758
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200593
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AH-23848-6903	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69374
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415257
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51074
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2555
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
hydralazine-2311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14331
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	2.23623
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90972
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1268
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45855
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916931
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
BRD-K63145939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00686
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09841
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0063
POU4F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62541
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44261
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04876
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6637
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99835
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36481
BRD-K83586473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17502
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920757
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.053148
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2116
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996475
Perturb_7491_KD_MLLT3_SRP174861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839128
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976073
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350262
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6331
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95341
oxyphenbutazone-3582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36549
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
HO-1-N-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76453
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08436
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K34632780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1376
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52242
CRCGN015_MCF10A.TP53.M_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08945
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00859
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25208
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949635
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00919
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7346
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42141
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10484
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934354
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05807
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963943
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444749
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.00694
biological_process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isoxicam-7268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442921
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19059
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36967
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959971
MDA-MB-361	GDSC Cell Line Gene Expression Profiles	1.0	1.43618
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05374
BRD-K43352598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10853
quinisocaine-4791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18133
PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9255
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72026
TBL1XR1_02_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.32193
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14603
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71035
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07624
BRD-K10148216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12209
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910046
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17296
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269409
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935803
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37892
CHD7	ENCODE Transcription Factor Targets	1.0	null
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
fulvestrant-7091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20651
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421659
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91832
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07641
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06006
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12781
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96389533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34426
6-bromoindirubin-3'-oxime-6559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40286
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84528
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.836411
BRD-K13425292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67663
GSE155305_3_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6379364-41598_2018_37489_MOESM2_ESM.xlsx-Sheet2_DESeq_MSC_vs_fibroblast-DESeq_MSC_vs_fibroblast_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BHT-101	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02688
BRD-K02630367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58747
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.837013
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18074484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34623
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282494
EBF1	ENCODE Transcription Factor Targets	1.0	null
ZNF384_02_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.37851
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58709
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62384
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
icSARA deltaORF6_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47195
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7458_KO_DHX36_SRP120505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.75326
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93448
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
zalcitabine-4799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14716
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0294
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15517
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34729
Caov-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51671
BRD-K55630970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25605
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52199
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875578
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75342
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10034
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26049
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19767
KYSE270	CCLE Cell Line Gene Expression Profiles	1.0	1.46775
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82249895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24287
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08749
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25787
intermediate stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16733
piperacetazine-3574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7737
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
SIN3A	ChEA Transcription Factor Targets	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826149
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972105
colecalciferol-6656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29A-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840797
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.860702
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968729
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91583
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222168
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68944
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18859
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76489
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27803
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.884491
BRD-K68731395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42852
BRD-K21470524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09868
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80208
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246103
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0193
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01399
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.00408
PPARD	ChEA Transcription Factor Targets	1.0	null
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93812
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hel	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26818
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51434
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985796
intermediate stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15225
LS-411N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61065
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35733
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90294
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01634
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.78254
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05726
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18728
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950252
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994956
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7144
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6685
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880785
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200446_0_v_3_srsf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
butoconazole-6288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440363
CTCF	ENCODE Transcription Factor Targets	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84916
PFSK1	DepMap CRISPR Gene Dependency	1.0	6.92053
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81472
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87085
CRCGN016_MCF10A.TP53.M_24H:C15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43273
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17696
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27777
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475477
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13939
AG-013608-5944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10716174-41467_2023_43919_MOESM10_ESM.xlsx-top500_STAT1_ChIPseq_ENCSR000EZ-ENSEMBL_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
NUMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53373
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K65561930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17889
ciclosporin-3267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Subthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34466
ANAPC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37539
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.887783
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69447
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31473
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28512
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58894
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12246
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87037
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36963
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639444
Perturb_14840_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.19379
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.859866
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.949143
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15027
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924129
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22021
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
phthalylsulfathiazole-4653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gallamine triethiodide-6215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08884
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48118
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851062
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36379
SK-MEL-24	GDSC Cell Line Gene Expression Profiles	1.0	1.54425
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13073
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.653911
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45218
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.70446
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38414
BRD-K75100119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44408
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970144
BRD-K09017160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00001
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63663
MCIXC	DepMap CRISPR Gene Dependency	1.0	3.4117
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5461
primidone-6723	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58025
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30929
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66224
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0496
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19183365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16441
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97572
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.41949
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23153
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A240-01A-32R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7818
BRD-K04143779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32407
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4430-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43787
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848795
BRD-K52468958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8901
metrizamide-3255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30964193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28439
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60238
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46502
SARS-CoV_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65805
dorsolateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60994
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.46689
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75704
methacholine chloride-5773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.0425
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05453
VIPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18466
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-5239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EWSR1_KD_GDS4962_468_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.78341
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040664
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.954556
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1565
zardaverine-4209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264573
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35489
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69113
PWWP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60301
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896688
acebutolol-4976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82738
BRD-K44613656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18041
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37159
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19129
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0319
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6528
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09309
GSE146865,GSE146866_4_v_3_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.989521
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71977
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54578
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
pregnenolone-4802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30899
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46457
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03918
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50673
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78243
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
ZNF384	ENCODE Transcription Factor Targets	1.0	null
19204204-SupplementaryTable1	GeneSigDB Published Gene Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08776
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835295
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40494
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 5 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15736
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04185
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19404
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41443
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	0.989858
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27788
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41167
BRD-K99078335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55688
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50475
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23033
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825314
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65844
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17589
cefadroxil-4161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58291
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE139455_4_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-MB-A8JL-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44816
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25429
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10876
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898453
BT483	CCLE Cell Line Gene CNV Profiles	1.0	1.35307
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890571
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858907
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09837
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43794
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977591
SARS-CoV MA15_Day4-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.35303
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57922
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24945
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20225
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06862
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51552
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836992
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32885
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96629
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12089
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930858
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16833
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8093
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900531
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38347
BRD-K18142082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12532
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.19424
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63217
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27117
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39014
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26249
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06704
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3408
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.2419
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221998
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71754
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24891
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.659738
Perturb_11395_KD_YAP1_SRP333272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.0326
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7634
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
ELK1	ENCODE Transcription Factor Targets	1.0	null
BRD-K64823749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25798
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
theophylline-3326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
haloperidol-1539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Perturb_6447_OE|KD_EGFR|TRIM24_SRP100743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05793
BRD-K75807957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26712
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56493
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845975
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM1	DepMap CRISPR Gene Dependency	1.0	2.35245
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74473
a431	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15654
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74963
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22746
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76222
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6276
decitabine-920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
loxapine-1516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25533
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898675
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04876
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91078
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.248
Perturb_9486_KO|KD_Prdm16|Appbp2_SRP359770	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.69881
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7680_KD_UPF1_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34909
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962165
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03328
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5251
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39182
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17741
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16513
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245625
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47932
BRD-K59049030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01532
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913053
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43397
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34342
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02005
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
S-propranolol-3523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7431
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09518
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28704
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27111500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25576
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26002
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26013
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69154
acebutolol-6631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE220287_2_v_1_mef2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16652
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88195
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74304
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18572
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.968902
BRD-K03512847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21348
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14662
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996475
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33577
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87164
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57537
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BRD-K24271020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15453
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1269
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48839
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910506
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51519
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44003352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96411
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07076
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19187
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924588
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.26231
BRD-K18352607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04882
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0588
REST	ChEA Transcription Factor Targets	1.0	null
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08664
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68933
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874598
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51934
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864758
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7006
SCA1_Knock-in_GDS1756_233_mouse_Forebrain tissue - 4 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51226
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16468
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4629-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71723
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19867
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20552
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29947
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16989
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.41229
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07534
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442857
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00916
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6341
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01243
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07783
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41583
ifosfamide-5805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-143	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A204	GDSC Cell Line Gene Expression Profiles	1.0	1.8558
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409916
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50587
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0479
mebhydrolin-4795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54262
BRD-K19652835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0545
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1756
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65964
BRD-K32146668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59237
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87128
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86217
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45203
PMC7843730__F2	PFOCR Pathway Figure Associations 2024	1.0	null
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43479
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39059
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cotinine-4650	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.352
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500742
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883491
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05220907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80352
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21781
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925335
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_4_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40276
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3259
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5842
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF772	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67023
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13683
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08843
genistein-1660	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459495
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DY-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12821
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-0.969415
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25658
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02996
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09147
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51267
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28405
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.998477
BRD-K27656392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15262
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUM159PT	DepMap CRISPR Gene Dependency	1.0	3.13181
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17129
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04091
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A47428621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88236
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30725
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77715
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862999
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961836
HOXB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37088
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32475
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72189
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.910046
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47431
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
CRCGN017_MCF10A.WT.HP_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73765
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12749
Lung adenocarcinoma_LUAD_TCGA-55-8091-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252288
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7543_KD_HSF1_SRP275505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469151
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31297909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27387
BRD-K55795421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3198
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81258
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374368
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6174
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914735
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72391
0179445-0000-4758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11085
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
polymyxin b sulfate_escherichia coli_gpl3154_gse31140	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88777
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21439
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nocodazole-2239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
CRCGN013_HEPG2_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13003
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4589
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.1519
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26049
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12484
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.603991
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40524
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46206
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931898
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95652
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939339
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37378
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10008
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00064
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63267
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92106
HT144	DepMap CRISPR Gene Dependency	1.0	2.96776
BRD-K46924722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29734
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.972091
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0001
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876661
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13624
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CWR22-Rv1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
D502MG	DepMap CRISPR Gene Dependency	1.0	3.23744
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69175
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98389
EGR1	ENCODE Transcription Factor Targets	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38109
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25208
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897638
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1579
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13018
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
capsaicin-4612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05433
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559027
HCFC1	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.135
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960867
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14636
spleen	HPA Tissue Gene Expression Profiles	1.0	1.14304
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55557
BRD-K02881560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34174
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
BRD-K36003376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56293
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93735
BRD-K04785821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59599
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76131
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.61694
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98887
ESR1	ChEA Transcription Factor Targets	1.0	null
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95797
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42904
aconitine-7149	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87593103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22958
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84115
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14547
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Somatomotor areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12501
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09908
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930789
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46738
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20488
BRD-K18173053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63373
eldeline-4306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200926
BRD-K04470135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6102
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
methotrexate-5419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859637
azathioprine-5627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06637
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42995
brain	HPA Tissue Gene Expression Profiles	1.0	1.30253
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5707885-6438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50815029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27715
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21442
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17795
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29198
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827161
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832173
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18147
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.09768
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318342
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19874
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00474
Perturb_17033_KD_Nr3c1_SRP149816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.76981
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02442
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4715
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.05124
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARA deltaORF6_36Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.50853
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84135
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17758
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
liminal part of r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38619
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75456
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14104
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07584
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01459
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912776
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82539
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8896
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06183
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09332
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256202
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853394
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.82414
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08673
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439333
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13021
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.39124
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	0.942162
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33454318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29107
GNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29999
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5456
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BRD-K40103182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32405
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30939
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61166
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55261
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48034
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3749
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223947
BRD-K91818277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02869
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14911
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08249
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54699
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855815
terguride-6459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gentamicin-5883	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.19962
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345324
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22291
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1285
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8062
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	0.857094
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
SARS-dORF6_84Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84344
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
iopanoic acid-6348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04693
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11151
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.132
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47445
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28082
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89985
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84504
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24408
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66589
hsa-miR-1273f	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
SKMM2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.77228
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15183
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57168
IgM B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66786
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.96833
BRD-K48749255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28768
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18543
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888059
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3005
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31953
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402892
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.11677
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
oxamniquine-4006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
norethisterone-5055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.948306
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895671
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50194
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872169
sodium phenylbutyrate-407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12739
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46698
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
CRCGN008_HEPG2_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1803
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60875
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20639
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chenodeoxycholic acid-7310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50006
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18472
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84455
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47006
BRD-K03352270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3546
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.76266
BRD-K86155400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46042
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gibberellic acid-7330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A84764193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06469
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0272
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3508
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33549
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70161
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.98407
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13223
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977224
E2F4	ENCODE Transcription Factor Targets	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12951
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00835
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25717
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74545
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-dep_3dpt-ENSEMBL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22175
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM20C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7491
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66727
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5891
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973615
A3-KAW	GDSC Cell Line Gene Expression Profiles	1.0	1.45215
MEIS1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50004365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03219
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
prilocaine-4284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LU-134-A	GDSC Cell Line Gene Expression Profiles	1.0	1.57779
CRCGN012_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00188
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72642
NABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51428
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38828
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3853
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548e	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
BRD-K01899298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3125
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K11671824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34828
BRD-K99125195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34509
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
SC-560-6870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200506
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39931
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05668
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS12BM	CCLE Cell Line Gene Expression Profiles	1.0	2.65161
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74429
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31794
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69424
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
CRCGN015_MCF10A.TP53.M_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03685
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.86621
doxazosin-6642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17145
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
BRD-K39153737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92341
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65165
BRD-K35324337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59526
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5186-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
BRD-K01311880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07543
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54593730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16731
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11683
emetine-4243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23313
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92997
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93853
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923808
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39065
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33949
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
MAFK	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.02535
BRD-K99446825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36193
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29729
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66214118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93711
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15617
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22011
A172	DepMap CRISPR Gene Dependency	1.0	3.29178
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	1.53688
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23907
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
diclofenamide-6686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81805
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78471
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.21919
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7001
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39483
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07809
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1042
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21781
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33934
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
MELJUSO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63143
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clomipramine-6825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21006
BRD-K27049948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15951
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979459
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40356
metrifonate-1797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49019
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.132
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPC-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22461
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0023
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disulfiram-2215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66085
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91683
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.074
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-5908	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929457
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96655
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87542
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27182
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFPAC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43999
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309435
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8498
PMC3371315-NIHMS350140-supplement-8.xls-MCF7-T47D-SK-453_Down_MCF7-T47D-Supplementary_Table_1_ER-positive_FOXA1_signature_Genes_decreased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89321
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60067
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESC_V6.5_UP_EARLY.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03329
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01944
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39692099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26185
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21691
MAX	ENCODE Transcription Factor Targets	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10526
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
semustine-7487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESC_J1_UP_LATE.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32525
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45201
tolbutamide-3886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32758
RBBP5	ENCODE Transcription Factor Targets	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271924
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43755
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25954314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31515
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77569
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884666
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845003
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levonorgestrel-3708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82602
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30146
flavoxate-6326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37672
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1441
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenformin-3725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34383
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04644
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1835
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450892
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293797
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67967
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53805
BRD-K88583132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19325
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12968
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12293
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41082
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
SKNDZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3597
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4645
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04876
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81913
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06974027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5586
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HEPG2	CCLE Cell Line Gene Expression Profiles	1.0	1.74802
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02304
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840797
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22291
FLI1	ChEA Transcription Factor Targets	1.0	null
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
RAD23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77097
BRD-K14414396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21801
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831776
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5153
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895759
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.5015
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06028
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.81403
MTA3	ENCODE Transcription Factor Targets	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27126
southern	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33657
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93485
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833892
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18303
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969558
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48345
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308738
BRD-K48143921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26258
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04239
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2478
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14904
mantle zone of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03087
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.886616
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01553
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424817
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41574
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.685539
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2819_OE_ADHFE1_SRP073667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.1505
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15532
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02993
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357291
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03131
chlorambucil-4345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.08621
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859137
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3711
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0828
BRD-K19133474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00864
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1982
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07034
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27692
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37712
MDAMB453	DepMap CRISPR Gene Dependency	1.0	3.3206
benzathine benzylpenicillin-7359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33302
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62923
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40145790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43235
esculin-6310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958343
BRD-K95864593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56949
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890119
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05871
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839947
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84524
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alvespimycin-5573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47862
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
GSE253579_1_v_0_sectm1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
M07E	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75474
aminophenazone-6818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.02933
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12387
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862856
ciclacillin-4358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955615
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863347
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62883
BRD-K37271110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3625
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82643
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
PAAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88394
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13588
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.590074
Perturb_4868_KO_NEUROG3_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15326
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00542
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81416
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00425
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
18338247-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24819
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15376
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42374
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
simvastatin-3340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30625
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05446
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
CEBPD	ENCODE Transcription Factor Targets	1.0	null
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77284
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942189
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20313
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16852
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66146
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.17734
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2548
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1022
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35842
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26516
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GFI1_KO_GDS4204_147_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.55799
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10159
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
PML	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72783
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1527
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51231
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum	HPA Tissue Gene Expression Profiles	-1.0	-1.79785
CRCGN017_MCF10A.TP53.M_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2935
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79596
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26332
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15697
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
estrone-6448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380824
MEG01	CCLE Cell Line Gene Expression Profiles	1.0	1.94884
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66486
luteolin-6658	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.257
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.1921
UBB_KO_GDS3906_492_mouse_Testis -  14 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2030	CCLE Cell Line Gene Expression Profiles	1.0	2.40667
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286563
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.46233
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4908
Perturb_9484_KO_Tcf7/Lef1_SRP251706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.24989
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13796
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930549
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
zomepirac-6815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18944654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40817
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26253
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29852
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_167_KO_Itgb3_SRP305656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.82643
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972827
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	3.16534
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10414
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.34092
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09785
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875237
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6299
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87930002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19828
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.865159
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259708
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.728
KMS11	DepMap CRISPR Gene Dependency	1.0	11.5516
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0828
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.43106
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43654
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351233
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-dep_8dpt-ENSEMBL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63261
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02637850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32208
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29564
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301071
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826373
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468084
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28841
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70652938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7589
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
BRD-K42877297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81731
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06616
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983407
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26123
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19103
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22273
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.85187
NAXE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59537
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98873
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00574
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95526
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260883
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
betulin-3513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-ddORF6_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62929
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63077
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83002
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08836
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25205
BRD-K08759542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24727
RCOR1_02_204	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85197
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35298
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44233
hsa-miR-544b	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36987
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31183
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8493
BRD-K06507315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1881
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17751
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829269
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	2.78343
carbamazepine-919	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4635
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24103
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.41306
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4123
PMC7339813-Supplementary_Data2.docx-37-PRRX1_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
PCED1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70995
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09735
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02114
SETDB1-19884257-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56987307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00566
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849344
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18152
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
benzocaine-4808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RU-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19912
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73071
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.685539
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MGST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5133
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48694
luteolin-3379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFM19	CCLE Cell Line Gene Expression Profiles	1.0	2.14472
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15399
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77483143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06511
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08679
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07545
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24355
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1694	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
haloperidol-1244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
BRD-K87472370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21225
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0023
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81012
viomycin-7036	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00589
periventricular stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60944
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201217_3_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09215
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suloctidil-6675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40982
cyproterone-6806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.962251
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	GDSC Cell Line Gene Expression Profiles	1.0	1.74396
BRD-K04731905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57689
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07111
Perturb_8329_KD_FTO_SRP125734	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2559
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.47855
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935424
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02924
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36016
Perturb_1707_KD_Rad21_SRP132608	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	0.972894
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916112
quipazine-2782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dexamethasone-5797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50296
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_5_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amphotericin B-5404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.32126
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872853
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32603
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963726
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15692
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05744
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3621
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98491
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51984
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE193541_0_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
rectum_8d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08096
BRD-K05970499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45313
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18764
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NGFRAP1	Hub Proteins Protein-Protein Interactions	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23085
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12387
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-0.898269
dilazep-3665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849578
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67215
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.3249
BRD-A73635700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08011
tracazolate-7339	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46883
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436173
BRD-K17893805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31862
colchicine-644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02547
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
hydrocotarnine-2765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94621
rotenone-5943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78284
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.267
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2883
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07901
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.889391
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16967
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.872135
BRD-K57045425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64766
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17568
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54772
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3607-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840797
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
BRD-K69914820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11465
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03749
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1437	CCLE Cell Line Gene CNV Profiles	1.0	1.34112
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18229
GSE244072_10_v_7_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
clopamide-3220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16306_KD_FOXM1_SRP238685	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72006
BRD-K12034365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53561
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64148
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05385
frontal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03039
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967788
BRD-K11643336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75534
hydroxyzine-1524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5004
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4449
securinine-4493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58077750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01073
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vinblastine-7517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3196	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCIH1581	CCLE Cell Line Gene CNV Profiles	1.0	1.5242
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9724
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D4REFED48h_750_AR--Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
erastin-6417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56706
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08533
OPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47038
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47478
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21874
cellular_component	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
urapidil-6696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26098
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6845
BRD-K23017938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03923
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.836
levopropoxyphene-3543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN010_HEPG2_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02923
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07495
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.4883
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50566
CRCGN013_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37612
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02105
BRD-K18768614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07636
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20011
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845932
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289687
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47718
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A43B-01A-81R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5117
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0034
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917091
Perturb_4193_KO_Mbnl1_SRP057123	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.17794
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902205
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27902
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891774
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635574
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64999
BRD-K73952959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07018
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957421
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965191
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4527
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19955
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
Perturb_2089_OE_hTR_SRP179030	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50534
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14166
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06477
BRD-K44481920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00032
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12955
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930789
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66325
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00276
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61238
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
there	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1108
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343356
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.44023
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80921
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63025
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9179
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910811
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.57123
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.88253
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17159
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36984
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73886
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997852
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NCO2	DepMap CRISPR Gene Dependency	1.0	4.13544
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886099
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36466
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42792
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27621
ethionamide-4593	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86659
TAF7	ENCODE Transcription Factor Targets	1.0	null
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268208
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06835
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3105
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
D542MG	DepMap CRISPR Gene Dependency	1.0	4.14447
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN014_HEPG2_3H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02968
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27426
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71344
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40349
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03898
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36678
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1507
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3323
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18516
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49728
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400305
BRD-K18245187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02989
KASUMI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62414
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
NFIC	ENCODE Transcription Factor Targets	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
NSC-625987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51405
cisapride-5305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24891
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873517
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45698
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16833
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20242
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34595
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.91249
estradiol-2653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRPC4AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2479
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56136
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3119
BRD-K00610900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02736
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
GSE228413_2_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31222955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08306
BRD-K77627909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06631
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46734
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haloperidol-5638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208722_0_v_1_mkrn3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36449
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67824
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1127
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.656758
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65356
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971635
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00935
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
(-)-MK-801-6657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64204
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
people	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STOCK1N-28457-6906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
18757322-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979141
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.356
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.053
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.90745
GSE184475_1_v_0_il21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95002
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29184
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848144
PNU-0293363-6573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.37561
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42701
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74893
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82899
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226599
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naftifine-3536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12824706-BLOOD_BLD-2025-028441-mmc3.xlsx-Fig4B_genes_inc_expr_NRF1-gene_name_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05401
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.680572
membrane part	GO Cellular Component Annotations 2015	1.0	null
nefopam-4752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27901
ROS50	DepMap CRISPR Gene Dependency	1.0	7.40308
GSE151612_0_v_10_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03659510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11676
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71063
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2292
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81643
BRD-K00907050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16215
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8839
estradiol-1666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K22002184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31887
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0033
fendiline-3190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
tetryzoline-6069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95652
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927013
naproxen-1706	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826205
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46378
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86312
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38156
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866197
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223127
BRD-K69471644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12057
NCIH510	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05885
70Z/3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867257
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1138
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
oxyphenbutazone-6844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45642123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04652
naftopidil-7331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41107
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50072
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51924
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13687
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40045
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48419
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51387
lycorine-4365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
greater	GeneRIF Biological Term Annotations	1.0	null
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983192
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71977
BRD-K70936779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06802
coralyne-5418	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337489
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559213
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07545
HSD17B10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86083
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66939340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21014
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0895
NCI-H810	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54001
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5126
pralidoxime-5383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279836
BRD-K79370456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7257
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0738
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926454
15-delta prostaglandin J2-5228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE617T	CCLE Cell Line Gene Expression Profiles	1.0	1.35271
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99363
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.64386
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78699
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19926
MFE280	CCLE Cell Line Gene Expression Profiles	1.0	1.35223
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.456751
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04202
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4628
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48623
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heliotrine-3717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32885
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04654
BRD-K74114857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12784
metacycline-4143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02114
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF438	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21356
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79144
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50135
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00493
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382396
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40499
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
BRD-K82202634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03275
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.20353
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50413
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.46069
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827688
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38675
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gut microbiota (bacterial taxa, rank normal transformation method)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92435
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50999
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29906
Perturb_17205_KO_miR17/miR20a/miR92a1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39941
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.08753
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37468
thioridazine-4454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26108750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37566
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05014
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919143
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12779
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00165
BRD-K11566857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12
hsa-miR-4290	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52656
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04521
NECAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60317
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919289
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43386
SETDB1-19884257-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07665396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01774
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.52079
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17488
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850954
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34925
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52235
HNRNPAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35582
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36737
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832758
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211141
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08816
vinburnine-7154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01137
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.19542
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.69165
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14298
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
CPEB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67631
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05256
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5824
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30254
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4454
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCFL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68842
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32289
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09966
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09653
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52068
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57784254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01116
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09261
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36835
immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.5149
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21344
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57874
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00713
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30756
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.9916
HS695T	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
heart	GeneRIF Biological Term Annotations	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923808
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00612
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06791
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56273
EPHA4_drugactivation_229_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65599
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80177
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
harmol-6022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35908
EGFR_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16589
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	0.99547
MYC	ENCODE Transcription Factor Targets	1.0	null
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208072
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
loperamide-4672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884075
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00047
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823982
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327241
flecainide-3937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91286
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985608
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76706127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04031
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65086
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23191
rectum_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
SRY	ChEA Transcription Factor Targets	1.0	null
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04452
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50091
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10865
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13271
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00567
ciclosporin-261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11154
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19773
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06027
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36444
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ergocalciferol-6746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18127
occipito-temporal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892211
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06258
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830929
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17412_KO_Kat7_SRP346205	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17224
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19703
BRD-K21449711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15524
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44327
naftidrofuryl-6687	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0026
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.38316
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID4_KO_GDS4178_620_mouse_Splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15355
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
estradiol-5205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10701104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23014
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839755
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844765
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826788
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91467755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25823
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.418
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2002
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283791
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18942
LIVF001-018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08659
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3744
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844517
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887683
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ZNF419	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47005
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13137
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879844
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04796
BRD-K70428675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04003
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833244
HDAC2	ENCODE Transcription Factor Targets	1.0	null
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71812
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23743
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
WM115	CCLE Cell Line Gene Expression Profiles	1.0	1.36963
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
BRD-K92941354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44611
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00798
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
reticular formation of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16733
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36638
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.41132
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951148
hsa-miR-548o	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.93914
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70468140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85057
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46379
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18289
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831167
16-phenyltetranorprostaglandin E2-7541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19325444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44731
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36294
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-297-ARID5B_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5378
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.79052
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85115
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47579
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04386
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23524
genotype	GeneRIF Biological Term Annotations	1.0	null
oxprenolol-3568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13236
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.888823
BRD-K67403750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50617
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37988
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4B_BATF3_upreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32734
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2173
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49979
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
PMC8298514-41467_2021_24813_MOESM22_ESM.xlsx-ZEB1_H3K27ac-SYMBOL_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31568
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78938
BRD-K24523560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35213
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
wortmannin-5240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50737
JAK2_knockdown_192_GSE54645	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.15294
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53652
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05635
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77037
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900531
PHF8	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAPDHS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46245
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37742
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60114
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926878
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03112
BRCA1	ENCODE Transcription Factor Targets	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216181
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32434
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248694
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35471
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35433
OSC-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
hsa-miR-4708-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
NONO_02_93	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.37109
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.67455
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.19155
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86677
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02309
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827695
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970109
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09573
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45684
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33677
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15940717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06015
BRD-K88948585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44773
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18728
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229558
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32033
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.0805
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976046
SF268	CCLE Cell Line Gene CNV Profiles	1.0	1.39894
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935076
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3895
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08458
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44208
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46185
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17808
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848806
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08292
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02777
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970744
ciclacillin-3882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX5	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36729
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92187
BRD-K79829201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54979
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11713
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06886
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24794
CAL62	CCLE Cell Line Gene Expression Profiles	1.0	1.43614
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33964
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376867
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.46627
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3613
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901049
FOXM1	ENCODE Transcription Factor Targets	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00807
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94979
BRD-K37850190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38792
BRD-K74656131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03835
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829387
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59998
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06342
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970744
SNCA_KO_GDS4153_529_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K08929846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01263
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15752
trichostatin A-3872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25815
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54614
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47984
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02733
sertaconazole-6811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.12987
BRD-K70941721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04906
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923808
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2846
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01064
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07283
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13589
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39215
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11516
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
HCC70	DepMap CRISPR Gene Dependency	1.0	4.23938
MAZ	ENCODE Transcription Factor Targets	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41358
dexamethasone_mus musculus_gpl5137_gse10900	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1137
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982973
GSE136591_0_v_1_akap11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04951
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25794
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36465
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
mafenide-5079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.24275
16643655-1300GenesList	GeneSigDB Published Gene Signatures	1.0	null
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60214
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59702
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.907504
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02451
BRD-K12959846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05491
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10944
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.022
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380263
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.816665
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14166
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40424
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27915
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59898
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10176883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29143
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GB1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.62234
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molindone-4784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
troleandomycin-1465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
icSARS CoV_60Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.864912
BRD-K60729758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46682
Perturb_12096_KD_Tsc22d1_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39436
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97851
RBE	DepMap CRISPR Gene Dependency	1.0	3.71685
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14558
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10769
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77528
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13924
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01431
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379387
BRD-K60837711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76212
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253951
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5211
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9207
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838519
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10438
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29196
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248874_1_v_0_pcdh9_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.475
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67744
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838519
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3369
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34399
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
gossypol-3740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.52919
sitosterol-7332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50234
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18095
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP4K2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35204
A375	CCLE Cell Line Gene Expression Profiles	1.0	1.57985
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918644
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890571
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59472
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07111
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Isolated growth hormone deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
pyrithyldione-7153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02816
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.71745
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
sulconazole-6652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49185
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	2.26953
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.555
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69924
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-11_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469076
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.39044
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7337
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82976
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54744
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.48311
EHMT2_KD_GDS4800_315_human_MDA-MB231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02109
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22102
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15278
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
moxonidine-7343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16177
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53975
BRD-K56354139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11455
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
reserpine-3341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
azaperone-3573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6218
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70897
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86941
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21465
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1287
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67993
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94408
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10843
BRD-K53774433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40533
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54008
Hypertrophy	CTD Gene-Disease Associations	1.0	1.19933
Perturb_4595_KD_Trp53_SRP372551	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
HMGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207381
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869214
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3926
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06361
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12532
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
valproic acid-347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05796
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.60622
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923498
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.071057
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
EWSR1_KD_GDS4962_466_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48148
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_2_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48629186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49851
HDAC6	ENCODE Transcription Factor Targets	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839128
BICR16	CCLE Cell Line Gene CNV Profiles	1.0	2.10781
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83322
BRD-K26543702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1029
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10799
BRD-K42455150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05721
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852343
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.04398
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00756
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14207
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999536
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840899
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17959
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967809
dropropizine-5106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382127
estrone-6647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chlorambucil-3788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02793
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.7534
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2481
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313474
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61437
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16213
PMC3435504-msb201237-s2.xls-Supp_Table_4a-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11269634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16726
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9319
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87268
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05871
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SYK_knockdown_280_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53614
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26401
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.4678
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15465
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
BRD-K54639145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25643
BRD-K98586629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16427
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86992
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
5707885-6390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09419
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0944
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37312
BRD-K27680690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68089
BRD-K79199168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01545
PRKACB_knockdown_91_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76787
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27477
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13833
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22223
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6217
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996975
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02546
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54819
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
melatonin-3293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TTNPB-223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-165-LBX2_LBX2	Rummagene Transcription Factor Associations 2026	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.894902
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00645
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11022
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30584
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83783925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38629
pyrimethamine-4779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05967
SOD2_KO_GDS1080_128_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1587
BRD-K15269548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19044
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00338
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83439
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22181
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05534
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19671
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488149
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55035
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23198
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06315
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04329
SNU-C1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.9194
BRD-K84013239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56501
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93935
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02221
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14807
BL1039 (RCOR1)	NURSA Protein Complexes	1.0	null
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
monobenzone-6713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26758344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3665
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47752
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22094
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
r2 part of the ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15141
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41107
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01839
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5512
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857713
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7626
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14842
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61044
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56395
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
fluphenazine-5597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881596
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monorden-5579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970109
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89159
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10481024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04161
CAV3_Deficiency_GDS3552_558_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1667
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25115
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97371
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95245
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SETDB1_19884257	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.85815
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21439
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944129
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3605
BRD-K12003101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36748
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985194
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82347
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02763
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04995
BRD-K41389177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.98145
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41147
BRD-K18368161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11052
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44524
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71945
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00174
BRD-K10276373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13524
penbutolol-3534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44699
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301597
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07625
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
zardaverine-4793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56907
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.849299
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63375777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09055
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16297
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31446
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350227
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59396
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12484
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10015
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.00768
lycorine-6051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86704
BRD-K99022424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37221
TBP	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30153
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885113
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K94014790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63595
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29836
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830837
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35881
iopromide-6842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34377350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61737
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528449
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02673
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51195
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48386
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59848
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46221
BRD-K00853706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72776
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317194
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13602
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16381
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74808
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36423
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05017
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287257
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219569
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942566
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62708569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05232
hsa-miR-4324	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4411
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21904
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12616
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.898942
PADI4	ChEA Transcription Factor Targets	1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
cisplatin_dictyostelium discoideum_gpl5382_gse8287	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24649
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839947
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40495
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48611
rottlerin-914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93164
BRD-K38189757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18156
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22229548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22224
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5772
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05871
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
MEC1	DepMap CRISPR Gene Dependency	1.0	3.3923
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06391
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
BRD-K98695520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07035
BRD-K76611906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23736
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907342
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940749
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cloperastine-4732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
imipenem-2873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23989
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02065
ofloxacin-7372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32384
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03882
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32577
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	1.81835
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10897
BRD-K26217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41062
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20536
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29549
dimenhydrinate-6352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5636
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03352392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85799
ZNF383	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74839
hydrochlorothiazide-4970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34306
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54553
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19575490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63708
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32094
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87142
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827703
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50315
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSK3B_KD_GDS4305_183_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16131
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928526
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89447678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90408
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12787
PMC11216188-peerj-12-17616-s011.pdf-49-CENPB_1_CENPB	Rummagene Transcription Factor Associations 2026	1.0	null
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03472
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33126
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29236
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26283
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11303
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836573
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18296
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991898
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27653895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00853
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93584