association	dataset	threshold value	standardized value
ME1	CCLE Cell Line Gene CNV Profiles	1.0	1.55935
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
C4BPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508253
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.349
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NADSYN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00392746
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.676644
MAX	ENCODE Transcription Factor Targets	1.0	null
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3R5-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893828
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922194
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23243
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30347
XRN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00986824
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10738
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24116
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.43
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01869
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24064
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.66398
BRD-K11457257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01754
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64797043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53854
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19679
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2726
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04918
ACE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061697
IL1R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453064
PRTN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572166
SLC24A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078631
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08739
PMC7553775-elife-61287-supp1.xlsx-Muller_2014_DREAM_bound_genes-Genes_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35541
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69073616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20057
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904757
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11457
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40863
SNU620	DepMap CRISPR Gene Dependency	1.0	5.86333
SPP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047447
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K57169635_dacomitinib_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76803075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29553
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB1_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.75541
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.08995
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01422
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.899863
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.41485
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92421
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88996011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1745
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97931
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.084
PRF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00837291
FCGR1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492019
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44266
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51261
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88759
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.47609
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.48218
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15703
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.891762
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57228
THRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693655
RAB39A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691319
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFRSF1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00726584
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20451745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51923
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21454
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DC-43-KF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.783048
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5197
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.3408
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51581
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045503
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11513043-41525_2024_436_MOESM1_ESM.pdf-79-TGIF1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.14952
BRD-K44224150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25114
CRCGN015_MCF10A.TP53.M_24H:G18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58355
Pulmonary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
BRD-K30351863_NCGC00185090-03_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K46494135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63107
NEK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589077
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intrinsic component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918997
WB-82-EL69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200596
BRD-K85803608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35731
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41987
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K47821225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92981
SYK_druginhibition_285_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.6865
BRD-A60245366_AS-601245_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL18R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699168
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.498292
BRD-K30992744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.012
SERPINB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00474702
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835664
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.11
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10333
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40935
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10333
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.82479
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04669
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56113
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K88812218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6691
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11573
SNB75	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24565
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24267
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882886
CCDC116	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679442
143B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.892
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
L3MBTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602543
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66205
BRD-K03810133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1341
Feeding Difficulties	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.9522
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1_01_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60573
BRD-K33503286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07389
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90507
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29288
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.608263
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60726
Mitochondrial intermembrane space protein transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.64567
EGR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05751
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929414
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OPRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00864212
HMGN3	ENCODE Transcription Factor Targets	1.0	null
SRRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0112146
OCILY10	CCLE Cell Line Gene CNV Profiles	1.0	1.90133
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35412
BRD-K21416096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36063
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905207
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00789052
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4515549-NIHMS63168-supplement-3.xlsx-1B_HNF4A-reg_genes_post-treat-GeneSymbol_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76509
IL6ST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55053
PMC11513043-41525_2024_436_MOESM1_ESM.pdf-79-TGIF1_1_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4867
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-N87	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.18662
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05526
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35394
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.53033
STX1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522028
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHRND	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552995
BRD-K00744507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00666
Pyruvate decarboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44528
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00464351
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08349
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AB-21-VE32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314591
HuP-T3	GDSC Cell Line Gene Expression Profiles	1.0	1.49056
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.512
BRD-K45013226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.357
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75758
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25373
RELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00674403
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.34987
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32589
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nuclear type mitochondrial complex I deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24255
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K23299829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12117
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26722
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866603
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHL-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6108
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933913
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884779
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of metabolism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74537725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6314
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.60876
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45862
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05791
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4741
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06852
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03443
HDAC6	ENCODE Transcription Factor Targets	1.0	null
BRD-K52836380_AZD-7545-A_HT29_24.0_h_22.2_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.762
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle inner membrane	GO Cellular Component Annotations 2023	1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.84494
BRD-K28122619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16554
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17513
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TET2_KO_GDS4287_430_mouse_CMP - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAMSTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551871
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K78818514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44878
BRD-K04251837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79229
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70309
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
HB-24-GP45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320253
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2396
BRD-A70155556_NP-001236_MCF7_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51937785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3856
BRD-K55836749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14772
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26179
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46343
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AMH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588617
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1038
RUFY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509024
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12426
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92955882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17299
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02568
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42797
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34721
membrane part	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45583
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316581
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
IRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K39573478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41146
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PLA2G1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681181
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00063
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19613
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19606
BRD-K62256869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80766
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PECAPJ41CLONED2	CCLE Cell Line Gene Expression Profiles	1.0	1.36323
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-dORF6_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.9443
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32157
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.937986
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20972
KAT2B	ENCODE Transcription Factor Targets	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54149
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22878
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847823
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89935
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83116
E2F1-21310950-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16604
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12376164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63255
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042975
BRD-K54028343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67008
IZUMO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00887133
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70557
BRD-K17140735_-666_MCF7_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88625883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95818
b-lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.00455
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36881
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44772
SPATA5L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563725
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49644
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15865
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.23946
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99298
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.039107
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46725
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16549
NFE2	ENCODE Transcription Factor Targets	1.0	null
AD-50-WA90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275943
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26273412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5372
hsa-miR-3916	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00248
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEN	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.118
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661991
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-25	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97643
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUCY2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00777363
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00365713
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25608
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26493
PMC9035581-HEP4-6-1157-s002.docx-2-Supplementary_Table_S4_List_of_genes_differentially_expressed_between_FOXS1-positive_and_-negative_HCC_cell_lines_FOXS1	Rummagene Transcription Factor Associations 2026	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507086
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853169
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34454
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34002
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40546
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K31554491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50553
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16641
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33995
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67868012_PI 103 hydrochloride_NCIH508_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NLN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570366
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.627272
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91796483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17966
MYO3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0084639
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
SPTA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653939
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925869
YME1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565785
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29666
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31245
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16091
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.514896
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17766
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11748
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0553
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59464
TESPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00749384
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57242481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4793
SLR21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74713
GC-74-QF56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205977
CHD1	ChEA Transcription Factor Targets	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88657
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9614
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442559
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12488
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233962
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POM121L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481425
BRD-K18635665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53388
BRD-K97929312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33782
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30205
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39664
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947551
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55058
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856446
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21361
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VSIG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644195
BRD-K15502859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10846
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83655
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09285
BRD-K33461572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67319
BRD-K35646839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37804
SKMEL2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07633
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.47271
COR-L23	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.29086
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5974
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79752
PB-40-YB26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217012
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19755525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61609
BICR22	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51741
nb4	HPA Cell Line Gene Expression Profiles	1.0	0.993671
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14019
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22501
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35794
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02645
hsa-miR-124	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MTMR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00888148
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4742-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
2-aminoadipic 2-oxoadipic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28465
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923898
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82753
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873624
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02347
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39484
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LTA4H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579533
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62178
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916661
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31312
JUND	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05733
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35157
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16555
INSM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00804667
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00639
BRD-K32223081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87373
BRD-K68459574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02885
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893589
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999384
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76965
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.3177
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944143
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01092
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829431
CRCGN011_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03035
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221236
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30996
Perturb_17554_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K67740871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82001
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284097
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.582004
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47301
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15509
CDHR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0073088
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16924
DMS-53	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.26989
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845378
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46703028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01711
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205724
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1871
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4884
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LGR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568423
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63064
TARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747842
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17918
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21541
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865806
u2197	HPA Cell Line Gene Expression Profiles	1.0	1.30932
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02982
ELF5	ChEA Transcription Factor Targets	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIK3CD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00873277
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315126
SK-MEL-30	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65322
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_macaque_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20709
BRD-K49659981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13745
BRD-K14653235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84598
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29217
IDH3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628798
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.01803
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0463
Charcot-Marie-Tooth disease type 4K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
BRD-K49384706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25306
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03166
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.87428
Chronic progressive external ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82798
BRD-K09721867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87564
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26512
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00551
TADA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620965
BICC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829658
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46028
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.913094
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE143643,GSE143644_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11806
Perturb_2570_KD_FKBP51_DRP008309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84310612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04534
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.49973
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43743
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41436
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02191
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985476
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	DepMap CRISPR Gene Dependency	1.0	4.15777
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31433
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99298
BRD-K02337960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24941
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.388
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8786
PRKAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00340842
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234221
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ca-Ski	GDSC Cell Line Gene Expression Profiles	1.0	1.42993
PCK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00747328
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618833
IGDCC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00799866
PPP6R3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664656
MCF7_BMS-754807_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108686
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24957
BRD-K06550516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38401
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54456
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75775113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27019
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05764
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2377
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
TRPC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498574
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3493
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72291
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00842
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02944
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19784
GCIY	DepMap CRISPR Gene Dependency	1.0	2.08435
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
APOBEC3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061618
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A61825514_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570841
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.533662
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51021
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895262
KRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461347
BRD-K72317601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65991
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RD	DepMap CRISPR Gene Dependency	1.0	2.01502
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K23ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90176
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0070602
CRCGN015_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0798
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40906
CCDC85B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520652
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41347678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26654
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15302
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89786
NCIN87	DepMap CRISPR Gene Dependency	1.0	3.28546
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.25187
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
XCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467934
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969487
CRYBB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524849
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57138
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0236
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23635
H3K79me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	0.897012
Mitochondrial respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265196
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2842
BRD-A39407481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24101
PDE10A_KO_GDS4542_292_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
KCNA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00934356
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6873
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06079
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66856
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41557
PMC11321995-41556_2024_1460_MOESM2_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Unique_genes_with_exons_significantly_correlated_with_OTX2_expression_in_Group_3_and_Group_4_MB_tumors_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REH	Achilles Cell Line Gene Essentiality Profiles	1.0	2.37516
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC22A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534963
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868995
SLC9B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00949774
BRD-K24133999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08057
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18393
BRD-K67531128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67321
Mitochondrial complex I deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
Mitochondrial electron transport chain function	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11258
SST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520754
BRD-K70533557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP17A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00855787
MORN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00887836
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63318
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18396
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91395
OE-18-ZX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221316
CRCGN017_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.845
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DNAAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067176
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory electron transport	Reactome Pathways 2024	1.0	null
BRD-K62459624_T5212475_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE101527_0_v_1_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0501
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.941876
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01593
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.881919
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85457
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893562
BRD-K19710723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22397
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358466
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SD-12-UF05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214882
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.32145
IL15RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487268
BRD-K53647637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01723
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ecsit-NDUFAF1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.214
BRD-K07881437_S1107_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4537
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89909
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16379
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K94082609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48583
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06332
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16456
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846634
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487437
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040934
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12252
Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03696
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07939054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23941
A_CA_04_2009_7dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41794
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09732
ABI3BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00832647
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21866
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84289
BRD-K18724229_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19573822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36339
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5596
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
7450_RPL23_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.549784
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14805
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM983B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79515
TE10	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18282
ACVR1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058706
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70812
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.71694
BRD-K80786583_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BF-94-CQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481472
PMC9510835-Table_2.docx-1-ZBTB34_ZBTB34	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MB-72-YK93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294387
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32085
BRD-A98283014_C3930_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885033
ALDH3B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00714832
MCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522477
IGR37_SKIN	CCLE Cell Line Proteomics	1.0	2.22122
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07898
Nuclear type mitochondrial complex I deficiency 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIP5KL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569151
BRD-K52978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47339
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A84481105_thioridazine_NCIH508_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38363
BRD-K52838863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45129
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GALNT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497103
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.506233
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolism	Reactome Pathways 2024	1.0	null
BRD-K07813434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3761
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13231
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42494
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01179
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.794
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29158
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
PRKCE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645738
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68455
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12681
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12681
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37845
CCLP1	DepMap CRISPR Gene Dependency	1.0	4.49261
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04531
STAT5A	ENCODE Transcription Factor Targets	1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851752
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931461
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.689704
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.961836
BRD-K34232791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71328
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50344
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833067
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89032
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39547688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22027
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.740402
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	1.53221
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44215
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
Perturb_6863_KO_CDK8_SRP299261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.823462
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAMB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00338375
BRD-K63997411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02897
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05153
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16392
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2048
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OXTR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00928569
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10166
SEMA3F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619617
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834849
TOV112D	DepMap CRISPR Gene Dependency	1.0	4.20018
BRD-K51003626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68931
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13511
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904757
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5892724-fj.201700693R.st1.xlsx-si-CLOCK_vs_scrambled__ZT44-Unnamed_1_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62141
BRD-K00411149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59946
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1408
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23757
Perturb_13769_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44601
r2 part of the ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17777
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39825
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.38631
BRD-K09693670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92773
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.53038
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18747
HSQ89	DepMap CRISPR Gene Dependency	1.0	3.88123
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3085
ARHGAP24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00686493
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14776
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61359
GSE67266_2_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49473
BRD-A37704979_SB-203580_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22291
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
BRD-K37940862_NCGC00185684-02_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11756
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6924
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892694
GJB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563186
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.09927
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41209
BRD-K30269093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40047
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IL13RA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492444
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6007
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31353
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64284
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myalgia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K97348029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63284
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09905
RPS27A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787268
EBF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502405
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8958
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46844
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836395
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.960684
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30467
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71801719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28042
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25383
BRD-K03829970_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA3-21867929-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39752756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79863
ATF3	ENCODE Transcription Factor Targets	1.0	null
DB-01-BR68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312104
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19426
C7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518804
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26196953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16027
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DDRGK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0065632
BRD-K16154498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98893
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Organelle inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
Detroit562	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44263
TALL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.6233
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00964
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8943
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.271
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26626
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH211	CCLE Cell Line Gene Expression Profiles	1.0	1.52355
CCKAR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385591
BRD-K48029682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91643
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8232
SNU1196	CCLE Cell Line Gene CNV Profiles	1.0	2.83667
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00449
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10204
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07416
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579635
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33131
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.113
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056153
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45056520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24487
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27184
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13803
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07618
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0972
NCI-H2869	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.10606
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8782
BRD-A89471191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73314
hsa-miR-3145-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44605
BRD-K66401298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68306
TYK-nu	GDSC Cell Line Gene Expression Profiles	1.0	1.42033
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90877053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48227
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56042
ZNF384	ENCODE Transcription Factor Targets	1.0	null
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K22683888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07952
EPLC-272H	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19911
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49701
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Succinate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01946
PDGFRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064845
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23569
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03239
MTOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470573
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47649
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19537
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.134
TSPAN13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00625559
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49473
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7493
BPIFA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567393
BRD-K69347147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10184
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.16232
AF-16-IB77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214115
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
PKN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00376
SNU466	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64728
BRD-K70322385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18467
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03374
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82376876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29352
Metallochaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23931
BRD-K86988191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36046
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60751
BRD-K07383982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0177
HOXC9	ChEA Transcription Factor Targets	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50732
CNR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.01017
BRD-K14534138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62086
MXI1	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01331
CAMK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00759216
BRD-K70949282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3733
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057222
BRD-K94992087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46608
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31351
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Impaired Exercise Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986994
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41483
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37309
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.37852
brain	GTEx Tissue Gene Expression Profiles	1.0	1.52487
Mitochondrial complex I assembly model OXPHOS system	WikiPathways Pathways 2024	1.0	null
IL17RE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643344
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40439
ENAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0042118
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996759
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
7566_RRP7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522072
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40206
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410543
NMRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00617149
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15717
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289963
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55432
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02875
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952783
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922397
GSE203158_0_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18949
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60952
PRAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770134
serine-pyruvate aminotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28742
Poisoning	CTD Gene-Disease Associations	1.0	1.16035
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17312
PRRG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00798808
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839659
Cytochrome o ubiquinol oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46278
GSE86021_1_v_3_crenolanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072262
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
P2RY4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556221
RAMP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558697
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10063
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049983
BRD-K49159670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01441
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30967
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CACNA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701927
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22878
BRD-K21312826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34286
BRD-K96417480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63765
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44748
SKG-IIIA	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-76-HU27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219464
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MUC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424013
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KOSC-2	GDSC Cell Line Gene Expression Profiles	1.0	1.73783
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972122
8759_TBX5_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.609266
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6832
BRD-K86232678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20945
Mitochondrial complex II deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Nuclear type mitochondrial complex I deficiency 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217586
DD-30-SX80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248771
FOXA1	ENCODE Transcription Factor Targets	1.0	null
SPIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00903441
BRD-K81982648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77423
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42191735_buparlisib_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98423
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
EXD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624589
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23635
1040_C1ORF131_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.854061
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.879634
SPATA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00742473
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.99497
BRD-K19166598_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63271
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31476
POU5F1	ChEA Transcription Factor Targets	1.0	null
BRD-K33697018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32508
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11747
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BTN2A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470252
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886198
INPP4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579741
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1609
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53626
BRD-K63809385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74809
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.971146
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41785
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03613
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
HEC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.20522
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847779
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65532
ELK1	ENCODE Transcription Factor Targets	1.0	null
EDNRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00922963
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2038
STAT3	ENCODE Transcription Factor Targets	1.0	null
Mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.837
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05395
BRD-K47874568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70676
GC-40-VJ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380088
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912201
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13585
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43981353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10991
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905219
Barth syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
PPP3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00719135
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07319
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48326
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00764103
SRGN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692882
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941444
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68236
BRD-K71216961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51473
Mitochondrial disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
Pulmonary artery endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48418
BRD-K92458042_NCGC00183260-01_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633636
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5131
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.7292
GTEX-X8HC-1526-SM-46MWD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857456
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13145
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LGR4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636827
BRD-K74245698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28071
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78196
BRD-K47052171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51971
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77899
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96637144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42878
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922448
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81301
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986088
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14073
BF-94-NX85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256149
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96013
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54873
BRD-K36529613_P0030_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.493794
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
IGFBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00412642
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45502
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4406
SHISAL2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00807425
GB-84-KP45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331908
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A70155556_NP-001236_PC3_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K68347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07529
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.12692
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95588139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42557
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28851
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983475
TACR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579531
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6409
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.53391
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927172
BRD-K87479423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05614
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04508
SLC50A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00773302
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43546
BRD-K97421379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46224
9482_UBA52_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.568915
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17315445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26723
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05824
BRD-K32949071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70402
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964227
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1296
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38245
POU2F2	ENCODE Transcription Factor Targets	1.0	null
BRD-K80897487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73246
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTPRCAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595826
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NADH dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.413
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ALL-PO	GDSC Cell Line Gene Expression Profiles	-1.0	-2.19441
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Easy Fatigability	DisGeNET Gene-Phenotype Associations	1.0	null
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13801
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21415
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1096
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25249
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35326
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881817
Mitochondrial DNA depletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00714
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531665
k562	HPA Cell Line Gene Expression Profiles	1.0	1.36933
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51061297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04494
MRGPRX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542595
3677_HEATR1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.731059
LRRC37A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498867
Fetal Distress	DisGeNET Gene-Disease Associations	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05812
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19985
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72784
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.959955
PCI4B	DepMap CRISPR Gene Dependency	1.0	2.26399
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38697
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971657
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.826
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10937
KANSL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00763405
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51935
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25592
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270851
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39223685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24421
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88328128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34989
BRD-K33179234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87314
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895705
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65142
ZHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00878525
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51584
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854001
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5005
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4936
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59096
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66384
EP300	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00765375
SCN10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00959386
B9D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522641
CD38	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00753324
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Increased Serum Lactate	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36162
THAP1	ENCODE Transcription Factor Targets	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968908
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD109	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0078309
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12915
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.879109
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25278
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.558977
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509628
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06727
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56341841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18531
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.68837
BRD-K51974360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.126
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CI-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71726959_N9-isoproplyolomoucine_SKM1_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226328
CILK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728415
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56929
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.94022
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13269
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17542
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44842
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12838
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PYHIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00852665
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61447
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CC-15-MK46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266107
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04956
DGKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542702
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP3A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565972
BRD-K26503698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52728
Paroxysmal Involuntary Eye Movements	DisGeNET Gene-Phenotype Associations	1.0	null
IGF2BP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00577402
SNX20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00795722
ZFP42	ChEA Transcription Factor Targets	1.0	null
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.106
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49644
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09115
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11121
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32082
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10158
paclitaxel_homo sapiens_gpl570_gse19136	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891846
Fumagillin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
SLC26A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866807
height	GAD Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89065
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14831
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26865
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47538
GRIN2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689453
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-5	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.81284
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864375
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05124
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.02801
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27596
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.608783
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22445
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22904
FLT4_knockdown_103_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.04487
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	2.51725
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57223
G402	DepMap CRISPR Gene Dependency	1.0	2.51973
Perturb_6862_KO_CDK19_SRP299261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77273
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30701
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982447
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33365
BRD-K58715359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18484
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05334
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76551930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48759
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78933
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08648
GALE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566601
7466_RPL36_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557199
SRY	ChEA Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
BRD-K22591777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3064
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333174
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977795
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2467
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.02503
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174635
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64082
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76911
BRD-K14394756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48478
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03504
UPCISCC040	DepMap CRISPR Gene Dependency	1.0	2.48343
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94691
BRD-K82244940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03425
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08896
MSI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628252
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.81558
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7452
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89752
7507_RPS18_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.670688
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90358
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11274
BRD-K44432556_VU0418946-2_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K86104966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33948
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044993
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993587
BRD-K08982277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06664
CD151	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00634992
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH2087	CCLE Cell Line Gene Expression Profiles	1.0	1.485
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FECH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546928
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77199
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854013
hsa-miR-4639-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
TBP	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94888615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01307
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25709301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24128
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MS4A10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526175
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51688
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3366
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14846
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17143
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18801549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2616
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2688
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17952
BRD-K17171256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08474
Perturb_7479_KO_PTEN_SRP147969	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.45672
BRD-K00675675_CL 82198 hydrochloride_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Liver_GSE13440_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07536
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88656
BRD-K31546068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05546
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12164_KD_OVOL2_SRP352292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.98842
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00327999
Vomiting	DisGeNET Gene-Phenotype Associations	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.431
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00796562
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19123
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947071
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31322
PTPN14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694557
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846408
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32079609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13178
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00995
MAPKAPK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00286189
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1603
PRR14L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00445234
ITK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00650728
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S100A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00466815
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.603
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893562
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44772
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32302
Mitochondrial inner membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55725
TMOD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507836
Hypoxia_Astrocyte_GSE4483	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.819087
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24423
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41013
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278322
8MGBA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44222
LRRC37A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00827326
KAT8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00478074
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987702
GSE134375_4_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP36L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0070962
CRLF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00688749
GSE150688_2_v_0_ursolic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32491833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69927
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17155
IGROV-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.81286
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_ACTIVATED-RING1B_EWSR1-FLI1_activated_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36176998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10426
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IL5RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506482
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83788
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04165
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92643
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71758378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33731
SLC22A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549107
AAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047665
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00734947
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.71013
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A45889380_QUINACRINE HYDROCHLORIDE_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
LB1047-RCC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.77118
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Mitochondrial Complex I Deficiency	DisGeNET Gene-Disease Associations	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
SYNM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531133
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75682
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1586_KO_Myd88_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67248
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96479
LILRB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628053
BRD-K22610244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32122
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07041
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908626
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303106
BRD-K04848570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.309
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
BRD-K23241743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06429
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968004
BRD-K24220535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65106
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84879
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07776
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15021
BRD-K86587289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40957
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00826
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47081
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A172	DepMap CRISPR Gene Dependency	1.0	3.12333
GAPDHS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00717058
BRD-K53095870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66627
PPP2R2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605209
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74653
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867578
Optic atrophy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.788
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591729
BRD-K15290974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26186
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19679
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.50188
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.346
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15083
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47587
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.9062
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210402
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYBL2	ChEA Transcription Factor Targets	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18188
BCP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64
BRD-K56895780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61812
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92496
SBC-5	GDSC Cell Line Gene Expression Profiles	1.0	1.5831
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882474
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904757
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08592
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08586
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13204
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.50554
PSG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673527
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5089_NIFK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.529994
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-46-AX49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466221
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10285
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944817
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.336239
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904757
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K16551475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31066
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857781
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLSCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456439
USF2	ENCODE Transcription Factor Targets	1.0	null
ALK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053509
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354673
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237888
SHMAC4	DepMap CRISPR Gene Dependency	1.0	2.14883
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4033
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15677
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466148
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27527
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHIA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00494896
TAF7	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03311
K562	BioGPS Cell Line Gene Expression Profiles	1.0	0.832788
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ALAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689933
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29846
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835392
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88125
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27155
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37729
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12189
BTLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00717221
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-68-ZP95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22006
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GLRA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614832
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435624
TBK1_druginhibition_188_GSE53658	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43529
PFKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00976909
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94291
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46401069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17449
BRD-K35587518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65928
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DPEP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00665997
SNU761	DepMap CRISPR Gene Dependency	1.0	2.29145
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01729
BRD-K04508260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35236
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27015
BRD-K51934291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64212
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.71158
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81029
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47354
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04661
NFYB	ENCODE Transcription Factor Targets	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17316
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42186
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66073
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K53665750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7135
NB10	DepMap CRISPR Gene Dependency	1.0	2.2793
Respiratory chain complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.362
BRD-K49656278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48811
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938502
Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16592
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56161905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25106
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49343
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15289
D423MG	DepMap CRISPR Gene Dependency	1.0	6.51853
A704	CCLE Cell Line Gene Expression Profiles	1.0	2.53131
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86768
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDXP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584566
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK2_knockdown_90_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.92485
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07475
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21068
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
JHH2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38189
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPRJ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480798
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25632
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.626558
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73787
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.47487
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00807787
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24556
BRD-K97493608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68983
SPC25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594406
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELOVL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563019
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81669067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53783
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00567
BTBD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00690387
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24795
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65458
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23984367_S1040_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.511872
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00645
BRD-K57045425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06422
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20966
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14606
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827271
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10643
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0942
BRD-K56301498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32967
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67549
REH	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.32926
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07536
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22404
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267383
NPC1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596745
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.15
BRD-K04454173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07834
BRD-K22485581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43736
NCIH209	DepMap CRISPR Gene Dependency	1.0	2.94068
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03231
TXN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585175
PTPRH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00528732
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA42-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59472
BRD-K09499853_KU 0060648 trihydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30811
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295772
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51784
Inherited metabolic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01475
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKD2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467034
BRD-K70721203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6023
ITGA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676999
NLRP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484449
HMGCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565908
BRD-K90571714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60042
BRD-K34966483_7332649_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02256
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865884
CRCGN017_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06755
BRD-K00378498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39458
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929224
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907428
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05415
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03779
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.858875
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17597811-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63761383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53091
RKO	CCLE Cell Line Gene Expression Profiles	1.0	1.48125
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9178
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24331
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4741
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952916
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04914
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.18046
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIM23 mitochondrial import inner membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.535
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1993
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03384
BRD-K05992469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40692
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439128
RKO	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.71212
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27416453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26634
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K39705203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66434
BRD-K50924315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0027
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TEF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640952
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.91885
USP28	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594816
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273227
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925002
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271681
BRD-K89328601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12472
NCI H23	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.12075
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855491
AFF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711344
BRD-K12867546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17689
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60007
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52286
OLIG2	ChEA Transcription Factor Targets	1.0	null
DUOXA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00933793
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48145
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25665
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979917
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AHI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435377
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SYPL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00793396
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72188
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.528374
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4007
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52601
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80457
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08524
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07183
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75844518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0629
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65706
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97867712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19472
CRCGN015_MCF10A.WT.HP_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11278
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234054
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.05033
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8399
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	1.35495
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12083
BRD-K75784474_NCGC00188012-01_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54037
BRD-K82284644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25603
BRD-K89364982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19551
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22473
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74989
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90083
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0122
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920483
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436114
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K10871135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67155
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4583
ZBTB16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689119
BRD-K10571700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51841
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23563
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956276
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02122
NPFFR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586186
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876623
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PBK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641766
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951508
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15236
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42735
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HC-11-RK51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202642
PABIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615056
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.501
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44664
FOXP2	ChEA Transcription Factor Targets	1.0	null
NC-01-ET52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381771
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252581
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10573
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590558
no-11	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.88235
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542335
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53672
sirolimus_rattus norvegicus_gpl6247_gse35048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00395235
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20372
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01146
MELAS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07536
HC-86-IA49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261128
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93301
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15400067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82106
BRD-K44908880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12859
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269037
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.84145
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14513
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory Insufficiency	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75909618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21579
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040887
Hypoglycemia	DisGeNET Gene-Disease Associations	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51703
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.543967
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48467
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918363
Proximal Tubulopathy	DisGeNET Gene-Phenotype Associations	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16958
KE-37	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.75666
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34785
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IL33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104168
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61956
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09952
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PRMT8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00751739
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30422
Hyper-Beta-Alaninemia	DisGeNET Gene-Phenotype Associations	1.0	null
PDE11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00911983
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K18181387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82422
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23865
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81792
SIN3A	ChEA Transcription Factor Targets	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27993
BRD-K49328571_dasatinib_MDAMB231_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58432332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02169
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87155
MK 886	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.048
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3099
BRD-K34700473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38252
BRD-K05001008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1585
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.68107
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5294
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448239
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02546
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC26A10P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521234
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19769
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7483
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00776
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28274
2558_EIF4A1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.515871
DPP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671614
BRD-K65182930_NVP-AUY922_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665966
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBFOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00920216
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34311186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40745
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203272
BRD-K60850201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49808
1774_COPG1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.82215
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
OR5B21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00787953
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.007763
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880189
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04741
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PROM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00968465
BFTC-909	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54511
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hepatomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
CD84	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00783542
CRCGN015_MCF10A.WT.HP_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55508
BRD-K69031148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19827
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055959
BRD-K28488100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16325
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839659
BRD-K50140147_HY-10192_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65622
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34409
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89854
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902443
Respiratory chain complex III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.752
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K35960502_NICLOSAMIDE_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28521
BRD-K93486666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23607
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08105
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94875
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.889124
nadh dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.711908
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79358
BRD-K96624721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42334
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825871
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21074
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69099
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31279
WD-62-UB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202524
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.30702
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70028
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RASGRP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584889
SLC22A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566012
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03992
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP140	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647759
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
BRD-K46877890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84822
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14058
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.053292
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
1198_CASC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.6836
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00551
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
LCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00444023
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48874
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16278
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09261379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00717
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.342
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03478
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42436189_AZ20_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06256
C8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588749
BRD-K97257286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38701
BRD-K51577368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95747
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19724398_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Poor Head Control	DisGeNET Gene-Phenotype Associations	1.0	null
EW-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.66068
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22356
MAFK	ENCODE Transcription Factor Targets	1.0	null
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.836
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
2124_DDX47_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.543244
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OE19	CCLE Cell Line Gene CNV Profiles	1.0	1.36665
BRD-K96069147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07276
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81535
KP-1N	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.00317
BRD-K43126701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02739
EFM19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61173
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.59785
CCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640398
SBNO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497804
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11782435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4654
WD-62-UB45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20994
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.900781
CCND3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00297826
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971659
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32923
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97583
BRD-K24369860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61684
CD37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00441806
PPARD	ChEA Transcription Factor Targets	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86287
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96133
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45859834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20296
BRD-K39715006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28408
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41256
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49289
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85217
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5808
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH838	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.44187
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75583553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27318
BRD-K89333198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24029
BRD-K72721410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33715
FA-43-XS35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247081
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901409
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.49339
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92579
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329299
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
BRD-K65182930_NVP-AUY922_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SSP25	DepMap CRISPR Gene Dependency	1.0	3.15457
7438_RPL14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.874625
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47337
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39598
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SPINK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00725123
TLR9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00780103
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87069
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAS1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.02435
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.358
CD248	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647539
CHRNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508351
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.92915
Paralytic squint	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38704
Respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.978
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9210_TPP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.611485
SETBP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553665
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056715
HARA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8254
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K51320582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34116
BRD-K31081052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9251
CRCGN015_HEPG2_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1238
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51267
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70473
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06874
PAX5	ENCODE Transcription Factor Targets	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31201
BRD-K11674021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1457
RELA	ENCODE Transcription Factor Targets	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1798
KARPAS422	CCLE Cell Line Gene CNV Profiles	1.0	1.86733
BRD-K54247106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1344
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67562
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.22121
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842902
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62511698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06503
mitochondrial membrane	GO Cellular Component Annotations 2023	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17388
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.506477
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71738
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17661
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9642
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32423
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947394
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NAGPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610429
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-27a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
LN229	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8315
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921139
JD-70-IC84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24442
LE-33-GL18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274062
PYCARD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627347
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4578
FAAH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601834
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.2417
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21907
EB-66-IH06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306546
STK869906	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211777
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23699
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02729
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BDH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00392634
CCL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512617
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169859
Mitochondrial outer membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18886
BRD-K10241968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36954
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.972798
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17542
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041022
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM175	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605868
BRD-K75990394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37472
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMG1	DepMap CRISPR Gene Dependency	1.0	2.27276
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RGS13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574636
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EXT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044235
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262444
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17228
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32895
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3294
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0528
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13116
CUX1	ENCODE Transcription Factor Targets	1.0	null
BRD-K71944493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67734
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16088
BRD-K30649484_4-(aminomethyl)benzenesulfonamide_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VB-89-RG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484267
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.43261
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84019
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZXDC1_KD_GSE45417_686_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50435
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68818
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Zileuton_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165719
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24629
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328439
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49926
GABPA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3908	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.94272
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51017127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64492
NCIH1915	CCLE Cell Line Gene Expression Profiles	1.0	3.25702
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05135707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81699
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50725
TD-69-UA90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263361
BRD-K20069402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40505
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857797
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40953
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73534
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19278
DCST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515981
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20733942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45732
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64425085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36608
BRD-K26866198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64951
CD-26-MB82_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406331
BRD-K40175214_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-935	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980901
BRD-K12260399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76932
BRD-A77467113_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDGFRB_knockdown_114_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.93105
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250649
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0458
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312611
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528024
17533364-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K60456515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24517
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40828
BRD-K72687327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41092
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56438
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HuCCT1	GDSC Cell Line Gene Expression Profiles	1.0	1.49941
BRD-K17113870_Lovastatin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K15389388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04816
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524575
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29104
CRCGN015_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41625
Lung squamous cell carcinoma_LUSC_TCGA-66-2789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72347
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31948
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49943
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.802
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05432
BRD-K85525164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51666
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.36869
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29408413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19378
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28465
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KP4	DepMap CRISPR Gene Dependency	1.0	3.70981
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912566
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47242
SYK_DEPLETION_GDS3609_36_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.97943
B4GALNT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603746
POLE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00778523
GB1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33472
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30918
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69753
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361753
BRD-K75981085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58682
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919646
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11656
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.767816
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOXL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00374391
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GAS7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00533493
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922266
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73187
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966091
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33585
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253006
BRD-K06219419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39768
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.27813
HCC1500_BREAST	CCLE Cell Line Proteomics	1.0	5.0534
BRD-K07550833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12556
OCIM1	CCLE Cell Line Gene CNV Profiles	1.0	2.15544
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049983
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236363
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30051
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BRD-K68060538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67914
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71799778_BML-259_U937_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83947
Leukodystrophy	DisGeNET Gene-Disease Associations	1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02759
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872114
BRD-K31994521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50809
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9181
BRD-K72519034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22295
MXRA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0100263
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256951
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929414
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.517803
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63252
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.33842
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
9449_TXNDC12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.565245
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7657662__F2	PFOCR Pathway Figure Associations 2023	1.0	null
SAMD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473173
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDHA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00574385
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527741
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
EW1	DepMap CRISPR Gene Dependency	1.0	7.04955
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.846783
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13514097_S1120_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PITPNM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00641189
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41795
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.774597
BRD-K15876355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7947
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
5748_NOP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.591965
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07011
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13305
BRD-K42809349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13983
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.3486
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90782
BRD-K69718434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53992
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-17-WP43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59129
GSK3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575802
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
b-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1589
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39739
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38715
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50816
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55144248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03095
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95712112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53899
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977755
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3125	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC9746874-DataSheet1.PDF-43-TERF1_TERF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A43640821_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40315
BFTC909	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03617
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3963
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44433
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63455
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825736
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2379
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.857982
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32858
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1119
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.3245
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963577
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55698
BRD-K39489370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26778
BRD-K03262163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12949
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.86082
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37507671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16999
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890681
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SPTBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00776433
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62979
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27634
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45838
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42338
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2F1-21310950-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24372
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54281
BRD-K05837079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90081
TRIM28	ENCODE Transcription Factor Targets	1.0	null
SW1990	CCLE Cell Line Gene Expression Profiles	1.0	1.57692
E2F4	ChEA Transcription Factor Targets	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01961
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15174
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937619
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.704458
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00846
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46688
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891179
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540246
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33094
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dihydrolipoyl dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A69196860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29842
BRD-K55853030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55253
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908723
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	2.15797
BRD-K15019832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93547
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988168
BRD-K75738997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56534
BRD-K60587793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05261
BRD-K39649774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2329
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85028
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	3.08766
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2649
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5454
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31091
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32698
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.578388
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.427
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14019014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25753
BRD-K11282060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74638
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993652
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55609
VAMP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623202
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04318
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98046
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48874
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08775
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KARPAS-422	GDSC Cell Line Gene Expression Profiles	1.0	1.62391
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.13616
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42257
2114_DDX27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.516159
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909483
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20058
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3033
mitochondrial inner membrane	GO Cellular Component Annotations 2025	1.0	null
ABTB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602605
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517291
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29895
Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80803211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71037
HCC1599	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56455
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926407
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
CPT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542999
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
769P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43552
NCI-H2795	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.90176
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62504
BRD-K12184916_-666_MCF7_24.0_h_0.63_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCAPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00819422
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_GSK1070916_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127843
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7597
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03946
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88363
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.44823
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905164
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KCNJ5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526302
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.929402
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UNC93B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495479
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20525
BRD-K44908610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06237
CRCGN015_MCF10A.TP53.M_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0112
PML	ENCODE Transcription Factor Targets	1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDE3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00802514
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22455
HCE4	DepMap CRISPR Gene Dependency	1.0	4.14273
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833749
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-3.05607
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05261
ZNF276	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627596
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2264
RCOR3	ChEA Transcription Factor Targets	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HSD17B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0107448
PLAGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00885275
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18769
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11292
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2189
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040817
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OE19	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
PL4	DepMap CRISPR Gene Dependency	1.0	8.1923
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.495
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49491
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13968
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40332193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32968
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82852523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52593
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	3.83865
BRD-K06320746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44231
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21102
Sengers syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66285
BRD-K56411643_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_macaque_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60862683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82783
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Focal T2 Hyperintense Brainstem Lesion	DisGeNET Gene-Phenotype Associations	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20811
MICOS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35993
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.945238
AGMAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508782
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07809
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MPIG6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496797
BRD-K07281036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3964
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82394273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15403
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7168
deferasirox_homo sapiens_gpl570_gds3558	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00624964
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890305
7444_RPL19_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.519165
BRD-K43889095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09204
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_NCIH508_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DD-61-DY35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263724
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76542
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940373
BRD-K50477983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69328
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04716
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1298
UF-98-OM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243071
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
TD-69-UA90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340367
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4746
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
Geleophysic dysplasia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47239
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046051
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78761
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10563
DA-17-XI26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218258
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3877
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942138
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.21984
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853852
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03938
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841199
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01646
7569_RRS1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503618
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29571884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26698
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CLU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00532734
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231959
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846748
BRD-K56595246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63241
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIGLEC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00950117
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03562
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33062
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.42893
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89236
Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7312
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81949
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833046
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67846
GSE184892_4_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20883
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859487
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.2402
NCI-H28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54862
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1908
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.73572
NEK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556083
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0571
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42164
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81627
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98276754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10283
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHOV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00506624
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46259
8166_SMG5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.578508
vorinostat_homo sapiens_gpl10558_gse35242	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLAIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660654
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0058
BRD-K01577807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6696
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07366
STRADA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561478
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.48717
DSG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519043
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial metabolism disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K39016838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26381
Hypertrophic Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48064
COV362	CCLE Cell Line Gene CNV Profiles	1.0	1.65744
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81117
SNU761	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06048
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9840_KD_AF10_SRP134072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47324
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
BICR22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37522
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24008
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07277
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85453
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92365
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RVH-421	GDSC Cell Line Gene Expression Profiles	1.0	2.05869
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905219
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18086
BRD-K44004565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45926
ONECUT1	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08613
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3111
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.54275
IL18BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0076421
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32303
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0795
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0091
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1477
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04369
BRD-K47049026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21683
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0833
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sideroblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71277
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26017
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987394
OLFM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629674
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
LMO2-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25534
BRD-K08533345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1466
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09693
BRD-K14863829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16776
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55465
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
CDH5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556196
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34694
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7128
Perturb_7447_OE_MIR941_SRP096893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.66651
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85119
BRD-K15931098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27061
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tRNA methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K01754882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34019
ERBIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591985
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.06974
BRD-K24167233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49614
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833616
BRD-K65182930_NVP-AUY922_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32553
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08355771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51552
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1385
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
SIPA1L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00735726
BRD-K11566857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37466
Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CDK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00620244
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33743
MTA3	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34355
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23735
MITF	ChEA Transcription Factor Targets	1.0	null
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04809
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.977623
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12875
LIG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721523
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35127
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05066
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86103
KDM5D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372611
BRD-K81318113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67623
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295669
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56195
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59205024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2862
BRD-K31747470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43723
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2349
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00967
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38553
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
PPP6C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00889694
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491558
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.900221
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.747
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.23821
Brain Lower Grade Glioma_LGG_TCGA-DB-A64S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47901
BRD-K44975377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69141
BRD-K59182232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0642
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05745
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
BRD-K57972271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89267
mantle zone of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30131
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0613
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996502
SAMD9L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00752051
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36377
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5335
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318644
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79475
BRD-K84874502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16821
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95278
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993136
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54861
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15995
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
6219_PES1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.521474
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630838
a2780cis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6766
BRD-K49630153_NCGC00183226-01_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866703
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84646
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1083
GSE150634_1_v_0_cd28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830703
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42085
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
biotin-responsive basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Type 2 diabetes mellitus_Endocrine Pancreas - Islet Cell of Langerhans - Beta Cell (MMHCC)_GSE6428	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52127
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88173
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
143B	DepMap CRISPR Gene Dependency	1.0	4.78516
Mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.838
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04751
BRD-K07530355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05362
7466_RPL36_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.62367
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00568
THEMIS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582169
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5969
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.686913
3871_HNRNPL_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.506832
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356507
Pontocerebellar hypoplasia type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883481
BRD-K46526566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21508
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13285
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64332
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92803
HuP-T4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.30066
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10857
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.27524
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22914
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38279
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02271
BRD-A19500257_geldanamycin_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K84956158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14636
DHODH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540539
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4408
SK-UT-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.65151
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67181
Flp-In-T-REx cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.29232
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71494
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866182
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48496
ICOSLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00990744
KRTAP5-8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00436625
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49362
ChIP_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K55489373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55164
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEP89	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057788
PC-3_[JPC-3]	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.91733
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.65314
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00695345
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11064
U031	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.72279
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5705
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.26818
KLF4	ChEA Transcription Factor Targets	1.0	null
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12327
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NPRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00433812
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00377908
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872631
Perturb_3263_KD_DDIT3_SRP335446	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.54512
Fumarate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57565
BRD-K71251432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17385
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.509
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Mitochondrial complex I deficiency	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21327356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56215
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72519
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44015
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04648
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16159
BRD-A55408860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39957
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7476_RPL6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625258
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72417
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26171
MIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
KRT12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00755478
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54931539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24989
BRD-K05118964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48014
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8993_TMEM126B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.936618
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.993652
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8825_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
IL17RB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548085
FRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607145
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Mitochondrial DNA depletion syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
BRD-K92712671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26318
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227329
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10216
7432_RPL10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.509947
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6199
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00485452
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14014
BRD-K95160020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19809
Acute Myeloid Leukemia_LAML_TCGA-AB-2819-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06723
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99308
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KNS-42	GDSC Cell Line Gene Expression Profiles	1.0	1.42663
ep16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.33191
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608287
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08574
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200066
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890515
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9627
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894403
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877485
BRD-K54236126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37613
BRD-K47164766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2172
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45716
SARS-CoV_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.32998
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.69679
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844116
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303432
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K76450447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82676
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M9-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39726
SNU761	CCLE Cell Line Gene Expression Profiles	-1.0	-2.99338
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1302
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF396	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02837
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00699316
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.39012
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04841
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.3885
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.801419
CRCGN014_HEPG2_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01541
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GE-25-DQ65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231373
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13539
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20036
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88017
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48935217_S1364_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58852
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18756
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
COQ6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501923
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42787
3-methylglutaconic aciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52733
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62336
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7788
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perrault syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.8847
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11145
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU1919	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72649
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84422
BRD-K67014046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93904
BRD-K95615652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40817
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858771
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03835
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23536
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33551950_R2146_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.968228
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43711
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.675541
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.406
OAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00627836
RAD51B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0043226
SPINK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434999
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833142
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95937143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58658
BRD-K71007902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32165
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.20809
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01766
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868699
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	2.12803
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661624
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1049
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14618
7478_RPL7L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.730707
mitochondrial inner membrane	GO Cellular Component Annotations 2023	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10052
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09951
BE-42-IC00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262466
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02366
PPARG	ChEA Transcription Factor Targets	1.0	null
TGFB1I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00744086
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RBBP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00972806
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977987
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50193
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63154
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72034681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04916
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19537
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8377
BRD-K55256232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51138
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MSTO-211H	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.66291
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TFEB	ChEA Transcription Factor Targets	1.0	null
BRD-K87465930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41508
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.52368
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02655
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912568
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914017
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10983
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.106
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06072
CFPAC1_PANCREAS	CCLE Cell Line Proteomics	1.0	2.65507
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K02625776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25547
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67103
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ACE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00768742
TMEM216	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058306
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-77-QQ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274955
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GRIA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665775
BRD-K22298558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36224
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850125
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29178
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
HuP-T3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.3258
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RYR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764331
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.809
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.06722
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893798
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.33725
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86944
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30502
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78246
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K24977393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27548
Poor Eye Contact	DisGeNET Gene-Phenotype Associations	1.0	null
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.5752
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
4064_IGF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.557674
BMI1	ChEA Transcription Factor Targets	1.0	null
BRD-K83115645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68317
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43324262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4303
Aerobic respiration and respiratory electron transport	Reactome Pathways 2024	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07220430_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CC-70-BD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307185
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60807
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
Basal ganglia calcification	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
ZFP42-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65378
BRD-K62492257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14507
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371121
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991494
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17835
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33467
BRD-K11476310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30661
HCC44	DepMap CRISPR Gene Dependency	1.0	2.70412
GALK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509395
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865848
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6494
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05026
BRD-K43456755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05619
CRCGN015_MCF10A_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23741
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS-174T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898785
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.88437
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.802833
BRD-K50046044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32944
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6023
CDC25C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632918
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937097
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879455
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59436
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82168
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982021
RD_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	2.93927
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854423
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.7037
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21768
BRD-K77535986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01484
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.83376
BRD-K94325918_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75618633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30392
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31223
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42061
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11433
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21387
BFTC909	CCLE Cell Line Gene Expression Profiles	-1.0	-2.86963
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K62621376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18468
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76812105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40043
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50706
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37337
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6543
BRD-K23533429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28457
MECP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558571
SLC5A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664188
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49145
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19543
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0039714
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6601
ADARB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00663321
BRD-K74317118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62336
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67085
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24957
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965202
BRD-K92991072_PAC 1_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36078
CHD2	ENCODE Transcription Factor Targets	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297311
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3011
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14228
oxidoreductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084512
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976205
BRD-K78431006_HY-50878_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12175
NGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055853
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902513
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923296
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868057
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212389
GAMG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.96134
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888222
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76796
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0359
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830703
Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09393
BRD-K37892442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18636
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87539
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_46_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837249
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
ZBTB7B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049017
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.58405
Tacrolimus	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.82
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49976
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09282
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3844
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01001
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27249
HNF4A	ChEA Transcription Factor Targets	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45472595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04495
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76166
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990263
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892694
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08789
NIP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04506
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984288
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95294904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79343
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7594
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
BRD-K28360340_TW 37_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00078
Perturb_8012_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.49494
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43202
BRD-K28354175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44086
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35296094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25554
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944465
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
VSTM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643628
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NC-01-ET52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301693
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34546
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940946
BRD-K02180800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20647
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23635
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54837058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47824
Blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7444
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07411
USF1	ENCODE Transcription Factor Targets	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60052
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46623
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33414
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55995
ASH2L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606043
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08985
Astrocytoma_CNS - Brain (MMHCC)_GSE4290	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.42826
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
BRD-K67661742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64664
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20961
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867142
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222516
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45838
ZR7530	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69021
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00352
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17489
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01785
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43222
mitochondrial respiratory chain complex I assembly	GO Biological Process Annotations 2023	1.0	null
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24116
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08958
hsa-miR-615-3p	MiRTarBase microRNA Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30711
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500062
EB-09-OC36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677347
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.643242
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12866
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.93421
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59188100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39857
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01673
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49059
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37998
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10913
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
ADAM19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00768408
TCF12	ENCODE Transcription Factor Targets	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16921
EPHA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473836
LYPD6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00841135
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041239
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACSL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469996
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09882
HMPOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
BRD-K19435356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4688
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60124
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042044
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2557
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49267
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03504
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69293
Perturb_11621_KD_DCAMKL3_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.404
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K87107091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01724
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30084
REL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569456
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04095
BRD-K28140275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03296
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496261
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.06411
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18746
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10429
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POPDC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00659044
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24411
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33398
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_12_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03304013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50598
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16931
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78169765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31963
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.66776
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23185
NCIH661	DepMap CRISPR Gene Dependency	1.0	3.36352
Wolff-Parkinson-White syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96596828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2956
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987363
BRD-K99387963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70275
EW-13	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.88795
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10496
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.03371
RELA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00392631
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260234
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.59754
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	2.48764
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874057
RPMI2650	DepMap CRISPR Gene Dependency	1.0	2.20087
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11369
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RL952	DepMap CRISPR Gene Dependency	1.0	2.48451
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_4_FDC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3274
BRD-K56783915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67156
BRD-K73695595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42253
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65789952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27226
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.10296
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04998
H3K79me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894221
PMC9883165-41375_2022_1744_MOESM4_ESM.xlsx-CEBP_gene_module-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35960502_NICLOSAMIDE_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01822
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923016
ARH77	DepMap CRISPR Gene Dependency	1.0	2.80794
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14833_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11308
BCATc-In2	DeepCoverMOA Drug Mechanisms of Action	1.0	0.32
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.988
YY1	ChEA Transcription Factor Targets	1.0	null
RMGI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69262
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04712
BF-26-MB27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20216
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894271
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
Paresis	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_1769_OE_miR125a_SRP282869	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01999
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
u266	HPA Cell Line Gene Expression Profiles	-1.0	-1.72194
SLF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00765472
7499_RPS11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.581047
SDS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563564
NB10	GDSC Cell Line Gene Expression Profiles	-1.0	-2.46844
BRD-A46317335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61919
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.51551
MYCN	ChEA Transcription Factor Targets	1.0	null
DNMT3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00434533
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37055
BRD-K82397896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28317
NB13	DepMap CRISPR Gene Dependency	1.0	2.34123
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.9496
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04298
BRD-K40887375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9553
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30679
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87742870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56196
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.60184
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65791
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69355244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74193
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884316
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38579
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIM1863 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03833
NB5	GDSC Cell Line Gene Expression Profiles	1.0	1.62638
APAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603233
BRD-K64055724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33182
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54825
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NNT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00250813
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832531
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.047
GSE244072_2_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARIH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055923
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908764
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ID4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00887448
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03547
ETS1	ENCODE Transcription Factor Targets	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0966
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94326
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25289
BRD-K18268126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40379
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19397
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830703
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	3.29191
B4GALT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575761
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74842791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20853
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980322
Perturb_2747_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
FOXP2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861534
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5329-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL1RAPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00905285
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDUL1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01761
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.774
BRD-K46890865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3924
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51267
BRD-K91615044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51534
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897921
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5834
SARS-BatSRBD_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82276
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.0991
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17714
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05455
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31096
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94326
BRD-K41517267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23813
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32406588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02619
GSE134375_3_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM6A-18722178-U937-AND-SAOS2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81473043_-666_MCF7_24.0_h_0.35_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593388
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
APBB1IP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00903337
CTSL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005147
CCR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576897
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935452
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27723
Diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DA-10-HD17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207139
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.59429
ADGRE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560709
mitochondrial membrane	GO Cellular Component Annotations 2015	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31032
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35924
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GE-63-WI86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360296
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36709
CRCGN011_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2911
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87496
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20047
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366222
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7978
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64203
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liminal part of r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30068
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02449
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56677
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0134
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85834
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.049954
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04271
BRD-K71726959_N9-isoproplyolomoucine_PL21_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07939
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
PLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0086816
NADH dehydrogenase complex assembly	GO Biological Process Annotations 2025	1.0	null
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06066
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARHGAP30	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0104316
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41859756_-666_AGS_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH3A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00670466
7585_RTF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.620059
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	4.57728
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6534_POLR1B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.588883
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73014869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5656
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43344
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HGC27	DepMap CRISPR Gene Dependency	1.0	2.41427
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03656
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84203638_4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-(4-methylpyridin-2-yl)butanamide_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.86522
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0564
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HE-43-BS90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308916
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66169
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8401
DUSP16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554962
BRD-K16406336_METHYLENE BLUE_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44772
SUIT2	CCLE Cell Line Gene Expression Profiles	1.0	1.50267
BRD-K31197843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51793
Protein of unknown function DUF1370, TMEM126	InterPro Predicted Protein Domain Annotations	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19684
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41429
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02763
BRD-K20755323_-666_NCIH508_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957082
BRD-K21367867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33396
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09648
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.8634
BRD-K16940345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28865
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9489
ZNF217	ChEA Transcription Factor Targets	1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22308901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23456
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IL26	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00651444
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.04157
cyclosporine_homo sapiens_gpl4133_gse25200	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K25649596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38558
CRCGN017_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7347
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08738
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.890627
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7657662__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61957
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8339
PRSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495021
BRD-K98251998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03369
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264178
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30131
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-18-NB46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262184
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20913
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
MYOD1	ENCODE Transcription Factor Targets	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	6.0548
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2642
JHOS-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44281
SP4	ENCODE Transcription Factor Targets	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05814
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAOS2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05236
LRRTM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00826207
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091159
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92539
NCI-H2171	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36198571_WAY 170523_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5979-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76258
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01016
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933174
BRD-K86240647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28843
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987568
Succinobucol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.78
KDM1A	ENCODE Transcription Factor Targets	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24673
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25236
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834088
decreased susceptibility to diet-induced obesity	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6522
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06911
BRD-K11581306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16326
BRD-K74305673_IMD 0354_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DHCR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647487
OFD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00550402
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18273
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01859
LY86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0056687
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.02878
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08239
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43959
BRD-K49865102_PD-0325901_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ILK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548982
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
BRD-K45112293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23192
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0343
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88156
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K10925833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04135
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07725
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44426506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53693
BRD-K08359838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45821
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30204
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08414
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10494
cytochrome-c oxidase deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.398
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841199
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87374
BRD-K41859756_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12585103-pbio.3003444.s013.xlsx-List_of_genes_for_GO_analysis-List_of_genes_undergoing_significant_MXE_upon_PRMT5_KD_under_hypoxia_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36514
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841085
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235704
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44025
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864351
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.60181
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2141
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypothalamus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.55804
BRAF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0114069
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057403
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.74138
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58174
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00455623
BRD-K71427375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06872
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	2.69127
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0577
ABCG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525788
SV2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605991
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46689
CD302	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528677
PSG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00707404
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24312
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.976699
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
COV644	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12874
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31971
BRD-K99452971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13416
BRD-K74908937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2199
Combined oxidative phosphorylation deficiency 27	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
PHF8	ENCODE Transcription Factor Targets	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41702
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14795
BRD-K10634221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08942
P2RX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00640205
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27496
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.53084
VSIG10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066586
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03528
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928279
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1313
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.01568
PSMA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697155
ChaGo-K-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61612
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl96_gds2324	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989688
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45456
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1264_KO_Mll4_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36121
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV JFH-1_48Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.40798
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62217
Prostate adenocarcinoma_PRAD_TCGA-G9-6499-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF217	ENCODE Transcription Factor Targets	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Increased Csf Lactate	DisGeNET Gene-Phenotype Associations	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4673	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
BRD-K31348453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05671
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03853
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
LMNB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514609
BRD-K47271260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26256
7449_RPL23A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.526195
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06143
BRD-K54351451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32552
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-506	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848198
CRCGN017_MCF10A.WT.HP_24H:E09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61175
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10272
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67856
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06319
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00430847
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.1294
BRD-K29745629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65013
BRD-K43316594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17692
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70385
BCL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00983572
WC-59-RG09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.51295
BRD-K41102088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0169
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02068
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UNG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636397
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LD-00-HM58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444863
IRF3	ENCODE Transcription Factor Targets	1.0	null
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95196255_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW620	BioGPS Cell Line Gene Expression Profiles	1.0	1.99376
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28914
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K12866026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15411
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFKP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067926
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K92344227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22414
WHSC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K43926323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24471
NCIH196	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22752
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203197
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828315
hsa-miR-4645-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K43206373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05607
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842673
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35048
BRD-K03063480_PF-477736_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544052
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22720379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62944
BRD-K68953461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48607
SNU1079	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5667
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12531686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08051
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40255344_EI-215_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523818
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40115
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04494
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40565784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61157
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31003
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOCS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0116967
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22159
ASAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00969992
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35292
SLC12A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508191
INSRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606881
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59237
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15666
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32994
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67726
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05863
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28334
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	3.19013
BRD-K60557007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45401
IL1RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622464
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918876
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03215
BRD-K58041870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34269
RYR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00465307
intermediate stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05538
BRD-K70791360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.721
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K52194153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19534
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0295
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40686
Increased Serum Pyruvate	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58325
VDAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606617
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19806
CASP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475085
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37335
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.599
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06349
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.202
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
EZH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475709
BRD-K89931949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72839
U343	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03622
SP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36927
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01353
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04704
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
brachyolmia-amelogenesis imperfecta syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52401
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.491
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.62685
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55008
CPVL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585455
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.476037
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02578
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979099
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01106
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5401
BRD-K52319351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30759
BRD-A29734477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08617
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30989
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92345
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.922373
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4251
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71177
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.102
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11008
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02204
Decreased Activity Of Mitochondrial Complex I	DisGeNET Gene-Phenotype Associations	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T47D	GDSC Cell Line Gene Expression Profiles	1.0	1.64388
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356864
Sepsis_Hepatic Tissue_GSE1781	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.07799
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27648
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897152
SMAD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0146126
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840489
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31272
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36209
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329125
DETROIT562	CCLE Cell Line Gene Expression Profiles	1.0	1.56803
Lung squamous cell carcinoma_LUSC_TCGA-66-2778-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.582068
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57204
C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568046
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812931
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52063
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232306
WD-62-UB45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27858
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29515
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380832
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73027631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08243
Respiratory chain complex IV	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09285
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30613
NCIH23_LUNG	CCLE Cell Line Proteomics	1.0	9.71567
SGPL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00458072
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911942
HEC1A	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32534
MCF7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24192
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00463
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42455
BRD-K60781525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37171
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BRD-K46376359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63884
BRD-K77207661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53708
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46322281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34034
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26606
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36881
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00383243
SOCS6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00817215
BRD-K44497547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30084
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872401
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90811
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9685
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95875837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36081
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14379
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251332
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.997397
CD300LG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645625
Developmental and epileptic encephalopathy 39	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMARCA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00775762
GSE154577_6_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252108
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00358691
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75243062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82833
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1763
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15541
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378495
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48709
RNF2-27304074-CHIP-SEQ-NSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BF-94-CQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277555
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53274037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13123
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kearns-Sayre syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM6A-18722178-U937_AND_SAOS2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01351858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60635
JHOS2	CCLE Cell Line Gene Expression Profiles	1.0	1.90699
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18572
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905074
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61738
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0092
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18348
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Early myoclonic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26163290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03246
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00385891
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966091
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13623
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35292
BRD-K37276417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46082
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47715
SCH	DepMap CRISPR Gene Dependency	1.0	4.21143
BRD-K95653016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84958
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297832
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46469
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68008
POU5F1-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14111
APOBEC3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00846493
NCI-H1836	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54859
GP5D	DepMap CRISPR Gene Dependency	1.0	2.10263
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7574
Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56309946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27578
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11406
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55727377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05253
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4742
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BronchialEpithelialCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.958839
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24138
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40173
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
NIPBL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0111341
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.883575
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879032
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-5	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.1974
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28567
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLHDC7B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00489043
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00748799
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903272
ZNF263	ENCODE Transcription Factor Targets	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985511
CXCR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704844
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LU-65	GDSC Cell Line Gene Expression Profiles	-1.0	-2.50703
SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.7201
BRD-K41604824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39289
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC18A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523258
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2672
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91025
BRD-K47409867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0166
mitochondrial respiratory chain complex assembly	GO Biological Process Annotations 2025	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96648
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27623
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10288935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24301
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.68867
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.608953
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OE33	GDSC Cell Line Gene Expression Profiles	1.0	3.46034
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257408
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.881726
BRD-K72651085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68546
CRCGN017_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16854
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218844
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76005
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-16-XW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245102
ARID3A	ENCODE Transcription Factor Targets	1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991917
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16855
GATA2	ENCODE Transcription Factor Targets	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
SKG-IIIa	GDSC Cell Line Gene Expression Profiles	1.0	1.56194
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09167
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216201
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92166
LRRC8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00822788
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057759
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58017
PKLR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00738304
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890764
Pallor	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848954
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BLTP3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477506
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919163
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14719
mitochondrial chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174911
BRD-K59087082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43192
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40515
CKMT1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476752
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14788
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3165
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9063
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.784
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08259
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427613
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33119
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ART1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542029
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
786O	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32396
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16253
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06871
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51175
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77496
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865476
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36322
PTGER3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00788088
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06174863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26925
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38045
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674442
BRD-K60830482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24958
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83069
BRD-A94740628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53813
ANKRD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00549595
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964001
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02752
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Harel-Yoon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
SIN3B	ChEA Transcription Factor Targets	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07829
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42163
HD-18-YL30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208601
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66367
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878011
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
7525_RPS3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533757
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38729
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.8857
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1928
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.42711
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.016
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7868
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53532
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08775
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
HCLS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00476861
mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K34414758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31615
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64422
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35468
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636505
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7539-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333321
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53748
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7051
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44214
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14795
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2828
BRD-K15322427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48572
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963058
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67578
TAPBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548428
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spondyloepiphyseal dysplasia Maroteaux type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842927
JC-63-BE61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256732
TNKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511141
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313795
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Magnesium chelatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.586777
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mitochondrial respiratory chain complex I assembly	GO Biological Process Annotations 2025	1.0	null
Sarcoma_SARC_TCGA-MB-A5YA-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-514b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10040_ZCCHC9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.517614
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.03746
GTF2B	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00683
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39269
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.600383
BRD-K78122587_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73610817_NCGC00183371-01_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABRG3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00906451
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834506
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588548
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ISG20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557226
eRF1 methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.962
BRD-K64268886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23115
BRD-K42191735_buparlisib_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82495
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.852172
CLCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00745143
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62336
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39062
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870034
SPATA33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00647863
Lung squamous cell carcinoma_LUSC_TCGA-66-2771-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC3874167-supp_gkt849_Supplement_Table_S1.xls-DREAM_-_TSS_clearly_affiliated-Gene_name_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acidosis, Lactic	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08788
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841713
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19688
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5101
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
vascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37162
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408872
FLAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671319
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2751
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894825
ZXDC_KD_GDS5070_504_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ADIPOR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00676732
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15541
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858428
MDAMB415	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12542
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94337
Pearson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
GPR143	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00767003
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52589
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254806
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09263
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11634
cytoplasmic chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174087
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01382
Dentin sensitivity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49087
BPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00839624
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.313145
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3464
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.50958
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ANGPTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00729023
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81932943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19487
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06444
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
NUGGC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00829938
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
SMOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00806536
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09415
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IL11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0102116
HCC1500	CCLE Cell Line Gene Expression Profiles	1.0	1.57988
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44415466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85236
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHI3L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00866421
Mitochondrial complex I deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.455
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02535
BRD-K80761625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26547
PECAPJ41CLONED2	CCLE Cell Line Gene CNV Profiles	1.0	1.73822
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041226
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41511
PMEPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00810178
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
Perturb_17553_KD_MYC_SRP358852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.31148
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0441
BRD-K82910696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25799
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_28_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34072
SIN3A_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.30144
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953101
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190555,GSE190557_2_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7693-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02949
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10229
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08761
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38074
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.39641
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4569
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96261
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933937
4935_MED14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.546283
BRD-A79768653_sirolimus_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4967
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
BRD-K24143478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40251
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937619
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1243	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
LCP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588778
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07045
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424387
CCDC158	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00913091
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25081
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07536
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852788
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.541
S117	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56433
BRD-K99749624_linifanib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.4185
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
chlorambucil_homo sapiens_gpl570_gds2970	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BXPC3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26837
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ChEA Transcription Factor Targets	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00527
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400136
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09177
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89692698_-666_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K16943897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65953
vitamin c_homo sapiens_gpl6884_gse16590	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mitochondrial part	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07251
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29987
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01359
BRD-K70935154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36177
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40E-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.90676
BRD-K44692299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.378
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68605
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64838
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39191
USP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0070069
BRD-K11696795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11336
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55286
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00929152
Hypothalamus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58174
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.67843
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	7.85796
RBBP5	ENCODE Transcription Factor Targets	1.0	null
RKO	DepMap CRISPR Gene Dependency	1.0	2.36661
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41025
BRD-K78297750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20144
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36072
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59931
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AXIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486999
NCIH1838	CCLE Cell Line Gene Expression Profiles	1.0	1.58875
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.638205
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834434
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIGLEC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00915663
E2F4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19039785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47695
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.55817
A-CA-04-2009(H1N1)_48Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.30629
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IFNGR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593369
BRD-K89701103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78688
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GJB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514545
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4159-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-1080	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.35991
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07206
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13241
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487572
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GD-46-OD81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284451
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611222
BRD-K67902591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21036
BRD-K01754917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95509
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04648
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19547
Organic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
BRD-K95591068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27645
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857679
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76509
NR2F2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18133
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68405
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862728
ADORA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00645169
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15703
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953446
BRD-K63462027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23107
BRD-K41172555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14984
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.449
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPTX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533069
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40739
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45954
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27864
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08479
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04648
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17835
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866152
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970547
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52131
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08996
Leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.402
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32738
IGF1R-20145208-DFB-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879538
MAZ	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892583
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07359
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GAMG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75053
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67103
LYVE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00761705
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35246
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.28942
BRD-K49847771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09483
CTCF	ENCODE Transcription Factor Targets	1.0	null
CD8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585618
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06898
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202671
7504_RPS15_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.681812
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44177822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01523
7510_RPS20_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50676
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NICN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00939214
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926175
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
AMIGO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483447
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03651
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01273
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68162101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09347
tRNA (m2G10) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72503
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41387
SUGP2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
P2RY11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669497
AGS	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41606
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92712225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17257
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00453
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64517075_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UACC257_SKIN	CCLE Cell Line Proteomics	1.0	2.67668
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74056311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70926
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6588
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04202
SMC3	ENCODE Transcription Factor Targets	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.739886
ZFP36L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728273
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96164740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46863
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2493
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.837
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZM-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00730935
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356612
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13654
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.02949
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95485901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37548
TWF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621659
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.02705
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962477
BRD-A12894472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4766
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2168
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5720_NMT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.567359
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12195
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BC-84-BQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263139
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13793
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425711
BRD-K87779720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25015
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.04734
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39695412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46518
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46311
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02456
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201335
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRTAP4-11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601323
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38381
H2AC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590831
EZH2_DEPLETION_GDS2445_117_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UPCISCC154	DepMap CRISPR Gene Dependency	1.0	2.43025
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3619
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89013
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216325
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.830707
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03035
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842015
BRD-K06475437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62823
BRD-K27372445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46058
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12717
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0231
Intrinsic component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18262761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39888
BRD-K54025526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00173
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54721
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68229
BRD-K22481359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11949
BRD-K80807286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47207
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FB-85-ND09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267961
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RMG-I	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.24095
NB7	DepMap CRISPR Gene Dependency	1.0	9.34614
BRD-K32882942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68468
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319304
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05122615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30636
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.51226
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86362
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04302
BRD-K57516590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71836
mitochondrial respiratory chain complex assembly	GO Biological Process Annotations 2023	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10526
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16402
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06936
CRO-AP2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59007
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23543737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16982
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	2.69767
PMF1-BGLAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00726068
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00756612
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38452
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18396
ME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00342301
RCBTB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534783
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43214
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUPT3	CCLE Cell Line Gene Expression Profiles	1.0	1.99122
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04021
ZNF141	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00462831
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627351
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59319
BRD-K82399478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15836
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914148
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00769158
PRKAA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850932
BRD-K60905563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92615
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K88478877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41355
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.06377
18667080-TableS2	GeneSigDB Published Gene Signatures	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.84684
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.924
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830217
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAMK1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553851
Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244903
BRD-K87803080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64005
BRD-K87640319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59501
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12189
NCIN87_STOMACH	CCLE Cell Line Proteomics	1.0	5.10998
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
BRD-K94273044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37136
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06347
BRD-K99462197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36574
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
SUPT7L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00601968
CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KCNA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498835
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.13135
BRD-K24025166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31737
BRD-K56283394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78182
BRD-K70584304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24839
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	CCLE Cell Line Gene Expression Profiles	1.0	1.44784
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	-1.0	-0.847488
SPI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566744
EPHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00747489
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56991
Perturb_7787_KD_SART1_SRP044298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZPBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565786
BRD-K73319509_-666_NCIH508_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19351829-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.93523
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28377
BRD-K54964687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70835
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL7C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0094881
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45598
decreased susceptibility to induced morbidity/mortality	MGI Mouse Phenotype Associations 2023	1.0	null
PAQR7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00940354
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.50844
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BF-94-CQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476416
C1GALT1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596351
A_CA_04_2009_7dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91908
BRD-K48255349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05996
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97931
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13968
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08448
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08958
PATU8988T	CCLE Cell Line Gene Expression Profiles	1.0	1.39404
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48827
lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K05068331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07541
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.556252
SPI1	ChEA Transcription Factor Targets	1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673863
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98522669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04703
Complex I biogenesis	Reactome Pathways 2024	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.562243
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639101
KCNE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00869996
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0804
KDM6A	ChEA Transcription Factor Targets	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40754
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08478
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MSTO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00844213
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.666386
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03506
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887304
SNU61	CCLE Cell Line Gene Expression Profiles	1.0	1.40454
BRD-K11113009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36726
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565257
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00888
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97617
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920721
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	2.01673
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38981
PMC4954754-elife-15550-fig3-figsupp1-data1.xlsx-HSF1_Genes-Unnamed_18_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4279
KCNK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00768784
NB4	CCLE Cell Line Gene Expression Profiles	1.0	1.49598
KAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657912
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A56909893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8777
BRD-K90103010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85271
CRCGN015_MCF10A.WT.HP_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1336
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839166
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969747
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406685
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77214
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626542
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.612532
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9026
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18244
GATA2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K44430448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6904
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02213
REST	ChEA Transcription Factor Targets	1.0	null
ATXN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715773
Familial hyperinsulinemic hypoglycemia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89089981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55831
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K56334280_S1367_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.56451
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.22995
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0406
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83875224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10255
JMJD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701428
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217339
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4988
BRD-K42671261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16488
SIN3A	ENCODE Transcription Factor Targets	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53688
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.51081
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.862
SARS-CoV NSP16_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.543
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68692
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932479
NME3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00628543
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30614
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03796
C2BBE1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27087
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1423
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47614
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19551
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940405
NOL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00752792
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00352
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.091369
BRD-K49391713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38408
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_ATF1-gene_ATF1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07033
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08386
BRD-K04196669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12584
CD180	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00762034
decitabine_homo sapiens_gpl571_gse29077	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35412
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14513
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19766
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424519
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29053
6862_PSMC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.625693
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04399
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851272
BRD-K09473191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17238
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
CAL-33	GDSC Cell Line Gene Expression Profiles	-1.0	-2.04075
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257052
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00466121
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8185
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20259
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39232
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937619
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54332342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30264
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923171
BRD-K58140298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26044
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES	ChEA Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00431
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67341
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PL18	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.36169
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54149
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54955
BRD-K78904317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03212
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.763879
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04865
BRD-K91397206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04769
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.77845
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44693
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K82638914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.007
19096012-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61389
SIPA1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062078
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056824
SLC16A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646745
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CHRNA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714266
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09885
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.737
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892694
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848265
ALOX5AP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756908
HSPA1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0078647
TBX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465084
BRD-K78385490_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.42922
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.00898
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7145
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16924
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.27403
NARP syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alpers-Huttenlocher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
SSTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535442
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03833
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940212
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00704
BRD-K67572910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31259
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00493
BRD-K12306640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14113
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05538
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A73635700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12342
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43236
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980797
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040969
Integral component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
BRD-K52210941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31497
697	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29495
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.41257
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05957
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68604
EML4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619319
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919849
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16207381-Table1Sa	GeneSigDB Published Gene Signatures	1.0	null
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6859
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16488
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80832
INS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00658554
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03207
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:J08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2235
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.63484
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04378630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90805
BF-26-MB27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273341
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14043
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day4_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7988
RDX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505856
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55945
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843841
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OE33	CCLE Cell Line Gene Expression Profiles	1.0	1.7631
blood vessel	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NTRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720912
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34788
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972487
hsa-miR-27b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCI-H596	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.45783
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82021299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02937
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NADH dehydrogenase complex assembly	GO Biological Process Annotations 2023	1.0	null
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253073
ZNF143	ENCODE Transcription Factor Targets	1.0	null
MYBPC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541873
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27968
BRD-K47030799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23673
HL60	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63686
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1416
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atherosclerosis_Aorta Smooth Muscle Tissue_GSE1560	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.74119
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832187
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99498722_S1176_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38559
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26494
BRD-K16686330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04033
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16123
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.21076
TMEM33	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00815652
MDAMB436	CCLE Cell Line Gene Expression Profiles	1.0	1.36033
TE5	DepMap CRISPR Gene Dependency	1.0	2.64846
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20046
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13877
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30427
C32_SKIN	CCLE Cell Line Proteomics	1.0	2.93084
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09477
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29274
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00736
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986818
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01154
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00426
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284915
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K89935890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37229
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85589
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APOBEC3G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681646
SLC7A14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584322
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05561
BCAS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477634
BRD-K47980183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62448
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24196
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.44379
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26527
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91148
BRD-K01292756_Pimozide_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MOLT-16	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.42027
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
HDAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710327
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.93014
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01753
NUP160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00834287
3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
BICR6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44602
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59318
SAP30	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63012
CD300LB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526114
Lethargy	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38093
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14176
BMX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0121421
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.19175
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32065
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54964
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.54283
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NLRC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518802
CA-60-LK14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352085
BRD-K72843176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43224
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852317
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.106
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Mitochondrial encephalomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.817
OF-37-IT01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207165
UBTF	ENCODE Transcription Factor Targets	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.579876
GSE202434,GSE202438_3_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16734
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05876
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58295
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FI-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81522725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40283
BRD-K56285711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25555
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23022
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03359
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1196	CCLE Cell Line Gene Expression Profiles	1.0	1.41
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01747
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15366
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05048
PMC9883165-41375_2022_1744_MOESM4_ESM.xlsx-CEBP_gene_module-CEBP_gene_module_with_gene_expression_data_and_ChIP_target_status_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07277
mantle zone of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11065
B-lymphocyte cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELK4	ENCODE Transcription Factor Targets	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0662
VNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00690137
BRD-K90762344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72715
KIT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0137376
SMKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00850887
BRD-K25645002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11167
BRD-K47988839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12056
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abnormal Mitochondria In Muscle Tissue	DisGeNET Gene-Disease Associations	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02197
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4006
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08909
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872631
BRD-K92356505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00155
EOL1	DepMap CRISPR Gene Dependency	1.0	6.00507
RAB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03809
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45819372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0988
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87532481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77076
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18473
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48467
medial part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11008
CRCGN016_MCF10A.TP53.M_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01742
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845923
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04359
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40685
BRD-K16879434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16873
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.91044
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.98565
BRD-K38417094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.139
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18159
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40805
BRD-K32879108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46334
SLC22A18	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546217
BRD-K46561246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03548
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.49623
BRD-K41548770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87358
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01788
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25317
ABCB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504574
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
QD-39-YV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375293
i-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19817
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K19009595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18714
D-392MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-5.23662