association	dataset	threshold value	standardized value
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0272
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850324
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02351
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825739
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935217
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_5_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25056
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1075_KO_Il17a_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.10115
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.18026
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193282_3_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9991
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.184084
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.19083
BRD-K39179354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09126
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_downregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73105
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.880131
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29704
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	1.0	1.76949
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968891
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960576
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03406
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982362
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21588
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2689_KD_BMOR_SRP344304	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09971
Liver Diseases	CTD Gene-Disease Associations	1.0	1.23296
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.892953
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1886
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00057
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Barasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148403
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22605
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1442
BRD-K93811242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32128
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040239
BRD-K89436979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33473
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	0.978519
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.005
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58821
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4777-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71482
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10745
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69496
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35975
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.940605
nicotine_mus musculus_gpl1261_gse31004	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01955
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08067
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5213
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71933
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7313
BRD-K95537020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5968
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846797
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861999
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922286
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05563
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48538
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40292
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19453
BRD-K02914492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08734
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIH1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01844
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43322
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06745
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847727
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58913
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.7578
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01455
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917536
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64539
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28316
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6412
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.143791
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10193
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5719
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.159738
253J	DepMap CRISPR Gene Dependency	1.0	2.84738
MCF7_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156957
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912498
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.26621
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979398
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.555
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19618
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21789
BACH1	ENCODE Transcription Factor Targets	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91249
Benztropine (mesylate)_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0133769
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42248
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.117868
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MCF7_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143537
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6515
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6711
BRD-K12132610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45837
A549_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130798
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00368
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867015
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942006
TBP	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8827
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
daunorubicin-7507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27044
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56333
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843546
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
colchicine_homo sapiens_gpl3386_gds1753	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81413
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05071
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24858
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LS-411N	GDSC Cell Line Gene Expression Profiles	1.0	2.34091
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30947
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27289
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57702
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7535
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02914
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3174
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9318
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2923
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852939
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0199
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00372
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4241
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.29595
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5332_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40125
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
t30-blood-rna_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.99886
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93231
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48976
Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr4_158171481_A_G_b38	GTEx eQTL 2025	1.0	1.22819
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00804
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7417
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.957
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.68974
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87622
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00569
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.941119
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226408_2_v_3_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60774
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.471
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01021
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19492738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07122
BRD-K56437119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02875
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00016
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12947
BRD-K94277689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12066
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01713
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28076
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903875
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ribavirin-6018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90668
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874152
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32501
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9013323-13577_2022_685_MOESM7_ESM.docx-22-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.31029
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97643
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48269
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99229
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33726
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19988
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A69P-06A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.96619
LPS510	DepMap CRISPR Gene Dependency	1.0	2.58299
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_AMG-900_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139731
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29442
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14566
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41008
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886386
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.09857
ATF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05473
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47334
Brain Lower Grade Glioma_LGG_TCGA-DB-5276-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE200673,GSE200691_1_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OCILY10	CCLE Cell Line Gene CNV Profiles	1.0	1.50544
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62207
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932391
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972179
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11357
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_8012_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.51418
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.12634
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11841
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905271
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832646
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3708
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02313
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02074
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09785
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18264
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37179
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32136
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82901
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02355
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
resveratrol-2865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966254
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114447
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4318	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37801
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9923
MCF7_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108048
DLX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34453
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5613
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82882
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40702
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4663
MCF7_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134204
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12952
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888374
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38456
Acute Myeloid Leukemia_LAML_TCGA-AB-2934-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916506
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7648
CHD2	ENCODE Transcription Factor Targets	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56117
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7079
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31304
Perturb_8613_KO_Ctcf_SRP078142	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.80178
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81239
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75599
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06631
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92803
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1193	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
tubocurarine chloride-5449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1213
17699775-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17688
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.16039
GSE155777_0_v_1_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.24237
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.96352
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58913
SRF	ENCODE Transcription Factor Targets	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2255
spleen_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.848782
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.53
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.8729
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41221
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.0347
GSE250534_2_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.849251
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47892
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18643
IST-MES1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55096
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39819
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04026
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838291
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33459
OSC19	DepMap CRISPR Gene Dependency	1.0	2.85814
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22901
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0124
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35881
BRD-K35469110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11004
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16892
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
olaparib_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0155816
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56405136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47338
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30341
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06968
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33007
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.68874
hsa-miR-4423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K30220159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00819
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88862
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53221
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42546
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5719
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31034
FOXP2	ENCODE Transcription Factor Targets	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thrombosis	CTD Gene-Disease Associations	1.0	1.14954
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9808
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.45891
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.922252
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878918
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72159
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05603
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01941
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.3457
RCC 786-O cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.04565
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arrhythmogenic Right Ventricular Cardiomyopathy_Myocardial tissue_GSE4120	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37074
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
piretanide-3567	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9652
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88819
BRD-K80359388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03353
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77354
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hycanthone-5691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40023
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.98301
M140325	DepMap CRISPR Gene Dependency	1.0	3.22795
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8011_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.5229
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14194
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.530629
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45925
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
6-azathymine-4106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHA-00745360-3824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15426523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04401
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66703091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45724
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862419
hsa-miR-4273	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Perturb_15395_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05969
BRD-K12260863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12456
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25663
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4613
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3222_KO_Nhe1_SRP366933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.61559
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A689-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02087
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17492
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51919278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62184
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34553
PMC12171002-jcav16p2578s1.pdf-126-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929032
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
MZT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27631
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07781
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935552
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0814
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14185
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G8_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.59705
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
BRD-K55142307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0192
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32103
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10803041-elife-86204-supp2.xlsx-snRNA-seq_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03076
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29716
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02687
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204659
guanabenz-5703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60558
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
CAOV-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53875
BRD-K57894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34647
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28803
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.43455
hsa-miR-569	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27207
NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74103
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08418
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13447
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851542
TAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9444
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69905
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.64339
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94263
19797726-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00795
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.1253
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03241
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.06036
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20503
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117346
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4903
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.59285
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
flurbiprofen-6472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30329
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35753
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53853
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3341
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16589
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03152
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14239
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.17231
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4797-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	5.71539
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09404
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59391
Eye Diseases	CTD Gene-Disease Associations	1.0	1.08904
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931629
PMC7880901-NIHMS1649581-supplement-2.xlsx-DESeq_V7_1_and_3_vs_Ctrl_1to2_f-Table_S1_List_of_AR-V7-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1459
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Belinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108705
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.936434
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.975466
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128302
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
alsterpaullone-7051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.2129
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979746
ESR1_ECC-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU387	DepMap CRISPR Gene Dependency	1.0	2.45949
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34367
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.76504
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2286
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.85913
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4293
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14098
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.10521
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03997
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13192
BRD-K79228133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57625
BRD-K58208155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47024
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
daunorubicin-7525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1459
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829067
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45929
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03029
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37618
GSE203158_0_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OAW-42	GDSC Cell Line Gene Expression Profiles	1.0	1.81559
alfuzosin-3203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24925
PCI30	DepMap CRISPR Gene Dependency	1.0	3.47434
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35291
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90038
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20795
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875398
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.802
MAZ	ENCODE Transcription Factor Targets	1.0	null
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67812
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13972
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08182
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15581
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.57887
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46926
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.052
HEC251	DepMap CRISPR Gene Dependency	1.0	3.06122
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.44986
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.12254
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16775
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Penfluridol_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0143112
BRD-K52413350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14222
SPI1	ENCODE Transcription Factor Targets	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69878
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29257
Weight Gain	CTD Gene-Disease Associations	1.0	1.32015
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00399
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.15865
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1066
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48403
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2604
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27441
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03794
milrinone-3552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22957824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03778
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09205
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPMI-8866	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52734
Lenalidomide (hemihydrate)_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0315086
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5474
BRD-K41970046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54232
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47397
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2164
LXF-289	GDSC Cell Line Gene Expression Profiles	-1.0	-2.17203
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0199
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9894
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044289
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.856988
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97502
CRCGN012_HEPG2_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05646
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84443
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7648
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51047
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39702
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17096
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.775258
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60171
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49812
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57879
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08877
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4458	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51754
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6273
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27668
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0125
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.10388
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spectinomycin-2987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01185
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45883
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.46043
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11309649-medi-103-e37185-s002.xlsx-Sheet1-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20323
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3535
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5838-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939956
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50184
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15388
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23054
Sarcoma_SARC_TCGA-DX-A3UE-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01654
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22309
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8315
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4827
C3A	GDSC Cell Line Gene Expression Profiles	1.0	1.46595
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69808
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956811
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-610	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54485
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40953
acetohexamide-1870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15705
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80169
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16466
tinidazole-3813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56709
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05076
BRD-K57795803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42413
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_794_KO_Tnfaip3_SRP332632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44103530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86266
DMS-273	GDSC Cell Line Gene Expression Profiles	-1.0	-2.39723
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97643
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60392
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52699
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1425
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3017
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.40386
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0093
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52053
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33165
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37269
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017716
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845002
PMC8185471-mmc7.xlsx-DEGs-SOX15_peaks-Unnamed_2_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25678
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61159
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952996
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.1586
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04563
sirolimus-5980	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20713
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.61769
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47193
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04895
metrizamide-4156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K57507729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30388
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17371
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HUTU80	CCLE Cell Line Gene Expression Profiles	1.0	1.8559
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mesalazine-3584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10294
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937609
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832983
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3747
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.2898
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.41602
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916357
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.64332
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97901
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971675
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4217
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.992219
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8563
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06145
MYC	ENCODE Transcription Factor Targets	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.496075
Furosemide_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0172691
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.89392
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36473
BRD-K07388954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53999
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43074
BRD-K85362541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23779
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51137
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72462
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01083
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43569
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35384
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07592
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2404
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08198
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
K562_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160971
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04769
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.6702
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123699
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48866
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0752
Perturb_17908_KO_lincEvi1_SRP047452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56426
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aztreonam-2282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52762
CW2	CCLE Cell Line Gene Expression Profiles	1.0	1.58792
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.995685
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03063
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cefazolin-4708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PrPC_KO_GDS4352_359_mouse_Developing hippocampus from adults (3-mo-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87169
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12894_KD_IKZF3_SRP185722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18419
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12951693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22682
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10075
BRD-K78989575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16592
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-6562-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76515685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4223
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32946
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20288
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055704
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29948
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92372
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung Diseases	CTD Gene-Disease Associations	1.0	1.05793
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14684
Lung squamous cell carcinoma_LUSC_TCGA-52-7812-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7751
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0831
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66098
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC10985171-Table_1.xlsx-Table_S3-Table_S3_IPF_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66284
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62767
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1508
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84334
NCI-H460	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964918
chordoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3952
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872362
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17441
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.01512
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02865
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930305
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957953
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH441	CCLE Cell Line Gene CNV Profiles	1.0	1.47562
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90269
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80294
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84721
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29512
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30801
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902614
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175594
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16268
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9962
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8042
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
DENND4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95117
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.148717
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5504
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.37846
GTEX-PWN1-0726-SM-48TDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997647
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04402
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Carbidopa (monohydrate)_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0178986
GSE102870_7_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5419
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994773
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47199
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.719
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10693
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51172
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044384
A549_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110682
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862274
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6155
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23891
amikacin-6715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07347
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58047
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02863
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14308
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3879
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02858
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00066
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77178
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4074-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40073
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07267
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.77191
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52995
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925986
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.95912
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920855
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19998
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29445
PMC6377303-NIHMS1504983-supplement-2.xlsx-AR_signature-To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PF-00539745-00-5979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15389
km3	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6247
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65112040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82741
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28047
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10295
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90888
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29908
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36713
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
GSE162276_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939444
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27035
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57758
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
0179445-0000-4292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01867
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0177
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07107
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.90788
GSE169205_0_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0438
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852283
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12692
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01184
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85741
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5975_KD_TRA2A_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.57984
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
UT7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3532
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931773
NFIC	ENCODE Transcription Factor Targets	1.0	null
HCMEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09082
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.829891
JUN	ENCODE Transcription Factor Targets	1.0	null
BRD-K17893805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02597
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12467
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
xylazine-2788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35278
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.32187
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A4EM-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07952
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36954
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.25245
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15705
tropine-3569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25459
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170349
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22767
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05076
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01098
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47909
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03839
Medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97643
sparteine-2134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_6963_OE_Med13_SRP049167	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39635
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4266
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09825
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09242
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0313
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34654
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66428
BRD-K82024598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36224
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.936838
NCI-H1755	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85087
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0118
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K02637547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19356
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01859
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38408
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.79391
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3054
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900541
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54325
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987115
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838242
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_up_VENN-442_common_elements_in_HIF1_peaks_and_HIF1_genes_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.5691
duodenum	HPA Tissue Gene Expression Profiles	1.0	0.97639
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11878
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02007
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9604
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42032
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siYAP_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77143
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2208
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14597
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72076
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051021
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6231
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83801
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15528
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13064
hsa-miR-23a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29215
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21843
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3694
CTCF	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97643
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28823
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02931
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3126-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22826
Edema	CTD Gene-Disease Associations	1.0	1.11606
Lung adenocarcinoma_LUAD_TCGA-55-6971-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03592
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891621
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67603
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5292
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07596
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_DN-Ensemble_gene_ID_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.74916
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.19041
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09401
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38695
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	2.56546
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	3.80271
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11395
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05675
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus-1148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24311
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.908722
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4805
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0597
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20826
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
trifluridine-3559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12002
MCF7_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117565
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14721
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10394
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35881
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06593
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98032
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19091
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4062
bromperidol-2872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08724
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.471
MS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.11952
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847583
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03476
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64746
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.758
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05802
fulvestrant-6165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08117
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_2187_KO_Map3k7_SRP237503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.07035
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSDMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00289
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51207
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48004
Lung squamous cell carcinoma_LUSC_TCGA-66-2766-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1376
LS180	CCLE Cell Line Gene Expression Profiles	1.0	1.38624
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29106
BRD-K72936860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13728
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11398_KD_FOXA1_SRP292689	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87761
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44197
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28306
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7075-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02783
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57673
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3253
mRNA_NR0B1_19530134	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845512
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33971
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9994
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62620616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38577
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20159
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31442
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01691
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02858
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951149
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66647
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53809
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86334
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914769
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844921
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86462
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A76905089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25583
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22907
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39892
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.9208
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960576
Perturb_3053_KO_Ndufs4_SRP055928	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.08218
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58224
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25931
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06269
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46329
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35748
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83032
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979724
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57179
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975957
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	6.16255
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
TCF3_01_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62069
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11731
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chloroplast membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843348
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3507
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Liver_GSE13440_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.23643
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08331
LS411N	CCLE Cell Line Gene Expression Profiles	1.0	2.52832
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26362
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07709
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5531
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SIMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52932858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6039
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CCK81	CCLE Cell Line Gene Expression Profiles	1.0	1.82664
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54342
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16309
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46793
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31661
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09635
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5142
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ceforanide-6751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE64642_0_v_1_sirt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07164
BRD-K46790201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20832
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34957967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01825
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.92529
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960576
hsa-miR-98	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88665
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38632
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4283
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02858
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9526
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1128
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
piperacetazine-5834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10684
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050662
BRD-K72609226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70492
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35495
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64722
RCC10RGB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52267
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78266
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01457
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61667
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78960724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09575
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_5day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69241
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24601
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83091
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28328
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82733
IGROV-1	GDSC Cell Line Gene Expression Profiles	1.0	2.08032
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14284
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18987
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63885
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884118
PMC11216188-peerj-12-17616-s013.pdf-88-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.33523
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08319
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977688
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1161
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17851
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913506
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95781
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13954
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0403
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882382
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2904
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59165
Dexmedetomidine_A-427	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0110522
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963344
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11465
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835415
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.22758
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41790019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03359
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.26267
PMC3258128-supp_gkr715_nar-02838-a-2010-File008.pdf-3-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50134
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1761
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-let-7f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2031
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.00809
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.3472
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9635
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	8.30606
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09352
SNU449	DepMap CRISPR Gene Dependency	1.0	2.42663
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	2.20602
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12854
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44993
BRD-K50053371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11841
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5598
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54761
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.61782
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13807_KD_Qki_SRP116547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCIH841	CCLE Cell Line Gene Expression Profiles	1.0	1.77969
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67984
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984966
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
A549_PHA-680632_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115181
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14319
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K03902845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72001
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01083
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6940_KO_Rbm20_SRP403612	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.6932
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.940865
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996976
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7822
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862756
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57242
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50532
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44206
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13673
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-2.26334
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08727
Necrosis	CTD Gene-Disease Associations	1.0	1.63116
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.927
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972575
hsa-miR-23b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872197
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066586
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11371_KD_METTL3_SRP292228	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.95191
GSE42805,GSE42811_1_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2036
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162276_2_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06652
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52528
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.44436
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_5903_KD_DDX5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.54855
K562_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144994
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.475
BRD-K37961770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34192
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26141
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.72777
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LEF1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K44421266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01002
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14425
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870745
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7925689-41467_2021_21687_MOESM10_ESM.xlsx-A_HIF1A-Unnamed_8_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
JUN_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26285
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11066
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71273
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6751
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.20622
HEC108	CCLE Cell Line Gene Expression Profiles	1.0	1.91226
HCFC1	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.26785
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949626
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50012
hsa-miR-4715-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	4.47709
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08916
LS123	DepMap CRISPR Gene Dependency	1.0	4.75393
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Migration phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84178323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07197
BRD-A35323217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00872
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00209
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47004
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDIPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053117
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77203
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.408953
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NCIH460	CCLE Cell Line Gene Expression Profiles	1.0	2.84316
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08857
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26529
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881132
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73738
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08177
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.60577
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64305
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	1.44654
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.282284
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0489
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_DN-Gene_name_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01909
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.082
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08162
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04814
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9429
NFYA	ENCODE Transcription Factor Targets	1.0	null
Perturb_7000_KO_Acadl/Acadvl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16514
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.7021
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6748
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35257
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86576
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52754
hsa-miR-4724-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-let-7e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102132_0_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44264
hsa-let-7b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10463
BT-20	GDSC Cell Line Gene Expression Profiles	1.0	1.46769
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44163
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14316
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34599
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0523
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K17421394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42125
ELP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
CYP2D6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16358
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9759
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49008
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041745
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07155
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76656
OTS514_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0148955
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1283	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-A50287893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20105
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02929
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
BRD-K45717258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30846
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0714
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39744
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45035
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
etidronic acid-2985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94398
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01932
NFYB	ENCODE Transcription Factor Targets	1.0	null
ChIP_POU5F1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5679
GSE179002_2_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OAW42	CCLE Cell Line Gene Expression Profiles	1.0	2.32862
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11387
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00451
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65368
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087575
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69558
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98921
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847874
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.37466
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03751
KYAE1	DepMap CRISPR Gene Dependency	1.0	3.02394
sirolimus_rattus norvegicus_gpl6247_gse35048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050687
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52439
BRD-K93483334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02971
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952965
BRD-K36320220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08441
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93559
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-34-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.82701
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
Perturb_11444_KD_SLIRP_SRP069960	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6774
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9071
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35037
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886926
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11044
locus coeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02313
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96937
Dehydration_Hypothalamus_GSE3110	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.13467
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991059
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03328
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0338
UBTF	ENCODE Transcription Factor Targets	1.0	null
Perturb_3898_KO_TCF7L2_SRP314475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00003
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16164
membrane part	GO Cellular Component Annotations 2015	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18238
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5427
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959008
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26285
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K80469338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1937
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02895
ZFX_01_144	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.90106
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25529
Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.86513
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.964572
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.08786
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139218
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73927
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997565
Fetal Death	CTD Gene-Disease Associations	1.0	1.25276
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043113
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825524
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50134
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39576
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42914
zardaverine-4209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07774
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99412981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06954
GSE164726_0_v_1_phf10_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26018295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85447
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1703
bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.97296
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90349
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6948
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862359
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48608
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ar_21330406_lncap_lof_human_gpl570_gds4113	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.101007
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875469
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.75888
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21902
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1693	GDSC Cell Line Gene Expression Profiles	1.0	1.45056
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93096
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38547
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89046
Prostate adenocarcinoma_PRAD_TCGA-CH-5748-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_ZM 447439_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117972
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16495
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-GSEA_siYAPsiTAZ-SITAZ_UP__MYC_EZH2_H3K27M3BOUND_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883568
Neoplasms	CTD Gene-Disease Associations	1.0	1.43837
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-877	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31269
BRD-K11667893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22595
phenacetin-4111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20003503-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2923
Perturb_3223_KO_Nhe1_SRP366933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.38928
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.966578
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oxyphenbutazone-3582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3588
K562_YM155_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167861
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1667
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48821
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.71916
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53267
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5186
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86375
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07875
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18125
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.34915
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t30-blood-rna_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.76113
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
17699775-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.42967
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K94582731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20711
Perturb_14084_KD_FGF13_SRP114701	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.35771
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31634
hsa-miR-4653-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
khellin-1504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4180_KO_Tsc1_SRP279018	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.8839
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.941066
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08724
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Subceruleus nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.50134
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986255
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73039647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13981
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61018
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.285138
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.04543
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07817
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.601836
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3792-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral ventricle	HPA Tissue Protein Expression Profiles	1.0	1.58835
Perirenal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	9.29754
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of alar m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18426
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09184
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.088
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63189
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80682
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839141
BRD-K44121468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28159
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	3.53766
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5327
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18675
SNU719	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96678
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85791
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1376
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53289
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39048
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46254
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17218
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6216
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18733
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03406
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15613
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13485
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981258
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4077-01B-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K42333498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39354
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18438
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1648
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vomiting	CTD Gene-Disease Associations	1.0	1.14473
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC1	ENCODE Transcription Factor Targets	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944618
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9036
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829499
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3607232-mmc3.xlsx-RUNX1_targets_in_K562_and_SEM-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861096
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.02114
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02048
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971824
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28419
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944615
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981984
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995449
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831814
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.871593
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	0.876386
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11099
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12985
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900164
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81012
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05115
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13673
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	1.0	1.99581
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85367
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9815
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40102
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22025
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43234
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EGR1-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00566
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35184
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52536
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3127-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43803
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71323
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126493
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27502
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57719270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19808
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.455
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12162
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.595
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99097
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846691
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37453
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_AICAR_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170926
Perturb_14684_KO_Prkaa1/Prkaa2_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.15063
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890255
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.7767
hsa-miR-3135	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Excessive daytime sleepiness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45317
Perturb_5331_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93576
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9762
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38601
SALL4	ChEA Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888062
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919145
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48056
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907942
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45817496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26621
BRD-K17549032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92757
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2055
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89714
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32845
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67354
Perturb_11247_KD_TMEM173_SRP312511	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.2007
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833697
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29592
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938409
CH-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.50144
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54719
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946894
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73863
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866526
ethoxyquin-3764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09738
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.38052
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07769
phenelzine-4360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_12061_KO_Stat5a_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74789550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78408
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122101,GSE122103_0_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62208
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31276
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.885945
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75969
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0943
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38955
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979746
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0357
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36102
Terfenadine_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0227639
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50628
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14423
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18403
amiprilose-3000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2261_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.42928
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Chloroplast outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77134
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50017
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61899
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11625
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35624
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
etoposide_mus musculus_gpl6887_gse33626	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7930_KD_ZCCHC8/ZFC3H1_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25067
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.17231
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18904
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06896
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4568
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bcor_22012066_cn_aml_lof_human_gpl570_gds4280	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.587297
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56723
BRD-K03733288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11835
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39637
GATA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42854
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86991
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	2.84173
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17632
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1972
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3378-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49901
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48832
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.34868
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8467
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07464613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7825
POU5F1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09212
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56979
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05991
vitexin-2810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6634
BRD-K19396909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04421
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31694
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55731
BRD-K70875838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11331
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2126	GDSC Cell Line Gene Expression Profiles	1.0	1.49385
Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45935
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38802
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92015
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59491389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71342
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894256
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
FOSL2	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05528
FOSL1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7902-01A-12R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54395
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964248
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6142
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCAM1	DepMap CRISPR Gene Dependency	1.0	2.66824
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98711
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A2J0-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97574
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09835
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40857
EZH2	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.680981
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6445
20559987-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69454
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.999221
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6442
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40902
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10162
BRD-K21910317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08193
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41091
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04516
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.438263
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3132	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43846
Perturb_17249_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.56895
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878344
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7307
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904721
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853345
BRD-A06471483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94513
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41307047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06303
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55425
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37081
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906851
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89494
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28720546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02623
hsa-let-7a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Medroxyprogesterone acetate_NCI-H661	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0195538
BRD-K37780492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46951
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63102
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.34381
Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142630_0_v_2_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15157
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71175
KMRC20	CCLE Cell Line Gene Expression Profiles	1.0	2.08719
Perturb_12065_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20826
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63343
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04329
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69742
BRD-K69613314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26109
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4028
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53066
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35495
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16689648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86913
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41314
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63568016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03454
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02279
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32022
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1531
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01492
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89803
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62236
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.4012
periventricular stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10545
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911428
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36133
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3649	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02377
Hyperplasia	CTD Gene-Disease Associations	1.0	1.58255
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5154
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
17683608-TableS4	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-1273d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33868
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02995
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
nucleus of Barrington	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
BRD-K66541877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00317
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32103
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	3.43758
BRD-K12067186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52946
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.34635
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7638
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18754
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34602
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.03152
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13159
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87926
CAL851	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29318
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17058
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5239
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26523
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09143
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08727
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48935
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11362_KD_METTL3_SRP292229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.04563
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27275
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58924
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36256
GSE239844_11_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39493
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22415
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1647
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13926
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841269
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMRT1-21621532-FETAL_OVARY-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24858
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.12387
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06896
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80848
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70524
RUNX3	ENCODE Transcription Factor Targets	1.0	null
HIF1A_01_87	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64293
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00943
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_1_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46534
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13089
betahistine-4956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22527
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907001
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05076
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_PRDM14_20953172	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47466
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9177
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12058
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03241
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06916
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.62219
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22462
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72462
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0682
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siTAZ_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.30277
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23134
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20594
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	3.39621
intermediate stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02161
MCF7_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151953
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88822
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.15644
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827794
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846922
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.46043
BRD-K03815046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09297
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC85B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00078
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMTOKA	DepMap CRISPR Gene Dependency	1.0	5.85726
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24159
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51352
BRD-K28700379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15525
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4087
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35474
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05086
cefalexin-5250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11409
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2674
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.99368
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17999
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17250_KO_Il17a_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.4619
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10848
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12828
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.49527
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00610900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71878
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4095
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18737
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36941
HCC1419	GDSC Cell Line Gene Expression Profiles	1.0	1.42218
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.698
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897899
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synovial sarcoma_Synovial Membrane_GSE6461	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.25821
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03572
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.13621
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21239
hsa-miR-892a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32198
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39837
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.63676
ESR1	ChEA Transcription Factor Targets	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04669
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A673	DepMap CRISPR Gene Dependency	1.0	3.05909
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24557107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21321
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943305
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17073
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29794
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34622
Perturb_12063_KO_Stat5a/Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7434
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168076
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5633
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15319
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875867
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8169
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21147
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08528
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55526
BRD-K36643302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17345
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32933
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30723
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849839
hsa-let-7c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2646
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23404
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824596
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41847
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95145
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03122
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10203
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21358
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43253
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41906
TEAD4	ENCODE Transcription Factor Targets	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41442
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07071
Hemorrhage	CTD Gene-Disease Associations	1.0	1.15156
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93196
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.56869
Perturb_16934_KD_GLI1_SRP286421	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_MAX_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6122955-elife-33947-supp2.xlsx-HNF1A_activated_survival-HNF1A-upregulated_genes_association_between_gene_expression_and_survival_in_TCGA_PAAD_tumors_-_related_to_Figure_7-figure_supplement_1A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41297
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5737
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954072
A549_AMG-900_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136443
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920243
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.138
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3695
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983347
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16058
salsolinol-2791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04652643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52389
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97643
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20639
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19735
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28074
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98025
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72333
BRD-K27881453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58789
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9872
MG63	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
PMC12612227-41523_2025_836_MOESM1_ESM.pdf-207-ZNF880_ZNF880	Rummagene Transcription Factor Associations 2026	1.0	null
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9167
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.858531
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
59M	DepMap CRISPR Gene Dependency	1.0	4.63494
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31051
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19083
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7467-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7EL-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01055
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0173
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12391
tretinoin-991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73283
COLO-824	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60424
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
PMC5259899-13287_2016_455_MOESM2_ESM.xlsx-Down-regulated-Supplementary_Table_S2_Down-reguated_genes_expression_in_MESP1_negative_cells_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85353
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE216757_0_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02261
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88562
MASP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00638652
BRD-K01651394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42478
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21062
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08054
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10236
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11255
MYD88_Deficiency_GDS2650_652_mouse_LUNG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC12021535-CPH4-15-e70011-s001.xlsx-S21-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38915
THAP1	ENCODE Transcription Factor Targets	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983065
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63448
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23919
BRD-K23553911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90248
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76682
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00771
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51603
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34833
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10501
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0116
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88059
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921533
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMSYM	DepMap CRISPR Gene Dependency	1.0	2.0145
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98829
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24622
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LJI308_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0208219
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2414
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28808
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04018
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2036_KO_Nrf2_SRP408559	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.0798
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.915826
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01703
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860619
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93806
hsa-miR-3921	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36628
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0845
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49094605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37421
GSE252857_2_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51567
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24445
MJ	DepMap CRISPR Gene Dependency	1.0	2.65648
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75183
hsa-miR-561	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36437
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168123
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21637
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32645
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32263
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03689
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.12971
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38324
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46239950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.082
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEG-01	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41575
pronetalol-4104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91581
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44408
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_11401_KD_ECI2_SRP066238	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.838
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12923
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89803
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	4.30945
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867954
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1459
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7502
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69192
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987978
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25523
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968891
HIF1A_01_86	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61672
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.11388
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31951
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79749
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38272
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141513
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06027
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06509
EDN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00329954
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73056
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93096
Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4976
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73893
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A06327019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48346
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7486-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928399
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.40968
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06056
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73677
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92977
PMC6122955-elife-33947-supp2.xlsx-HNF1A_activated_bound_survival-HNF1A-upregulated_and_-bound_genes_association_between_gene_expression_and_survival_in_TCGA_PAAD_tumors_-_related_to_Figure_7E_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09294
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835049
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4944
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0176
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08577
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16382
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
CRCGN015_MCF10A.TP53.M_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0527
MM127	DepMap CRISPR Gene Dependency	1.0	2.07386
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28463
PMC7468443-Data_Sheet_5.xlsx-PolyIC_6h_over_LPS_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4059
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.068
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
diperodon-4498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11948
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12687
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38123
hsa-miR-205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02858
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33173
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887807
BRD-K15940717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93657
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40545
clopamide-3220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936482
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0146
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3920-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45103
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965632
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.062
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52915
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Raf-1_OE_GDS1925_166_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04006
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
Perturb_7118_KO_Prkcd/Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43108
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51157416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2098
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38261
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958747
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28025
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36632
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88638
SETDB1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06552
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89863
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54517
hsa-miR-4766-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_11361_KD_METTL3_SRP292229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.12453
hsa-miR-4480	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64664
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42613
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12274
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00641
BRD-K16862492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07955
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936686
Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.36203
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069253
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27661
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12321
chlorpromazine-997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7746
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42094
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30644
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39744
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.4862
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1695
propafenone-2871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17932
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
piromidic acid-2996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.5675
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.33523
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846477
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K27554804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04591
oxantel-5338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.010415
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03939
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56381552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59794
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.161
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16862
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-487-TFCP2L1_TFCP2L1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94487
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10813
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.970551
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26283
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1782
NANOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852298
Perturb_5989_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
15869706-TableS2	GeneSigDB Published Gene Signatures	1.0	null
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5573
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05895
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23912
hsa-miR-1269b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0932
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A08191729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78792
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.67569
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17297
BRD-K79709959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00421
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64834
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96874
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27458
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23471
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44207
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31536290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76452
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.895354
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836097
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02092
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29298
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045052
RCOR1	ENCODE Transcription Factor Targets	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16459
MBD4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18666
MCF7_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182754
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19701
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36521
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27592
cefsulodin-2988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32228
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887972
RT-112	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53887
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0971
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8663
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918297
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etynodiol-6479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2255
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06883
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3686
ML1	CCLE Cell Line Gene Expression Profiles	1.0	1.37028
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13639
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09396
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841582
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1862
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19752998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2106
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	3.13024
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09534
NR1H3	ChEA Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8877
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_69_KD_SMARCB1_SRP280151	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7344
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23459
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.75305
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.65244
hsa-miR-1303	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Infertility, Female	CTD Gene-Disease Associations	1.0	1.42401
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.40557
Vestibular nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63839
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01055
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59501
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A21891180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23369
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98582
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60402
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Zfp36l2_deficiency_GDS3574_153_mouse_E14.5 fetal liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10814
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4688
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46114
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS422	CCLE Cell Line Gene CNV Profiles	1.0	1.40847
HMGN3	ENCODE Transcription Factor Targets	1.0	null
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03036
Perturb_4672_KO_Taf3_SRP007832	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6718
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.2161
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04026
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17071
PMC12830621-41467_2025_67611_MOESM11_ESM.xlsx-Sheet1-Suppl_Data-9_Common_differentially_up-regulated_genes_in_high_vs_low_Mecom_MECOM_mouse_KME_AML_cells_and_human_AML_from_4_public_databases_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
Chordoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35055
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888888
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64016
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81823
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939186
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	1.37966
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1213
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.259
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15098
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059991
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6183
roxarsone-3511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871357
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02307
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37227
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33365
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53181
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2505
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08558
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3053
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48693
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6256
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919308
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.618
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09054
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42995703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30078
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47058
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841267
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31497
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.46595
Perturb_5968_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.79211
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75578
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Endometrial Neoplasms	CTD Gene-Disease Associations	1.0	1.15089
PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_POU5F1_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94346447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13641
BRD-K35717699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58822
GSE126621,GSE126920_1_v_4_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLIN5_OE_GSE44192_482_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988546
BAY-598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13763
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Naproxen_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.021887
Sarcoma_SARC_TCGA-IE-A4EI-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54727
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62625
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02775
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.471609
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
G402	DepMap CRISPR Gene Dependency	1.0	5.19244
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88552
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69251
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02599
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K05789358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4588
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863077
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.08726
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32469
hsa-miR-3143	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2039
ARID3A	ENCODE Transcription Factor Targets	1.0	null
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07232
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23282
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18994
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25611
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08724
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.94883
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5025
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3128
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77354
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46929
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833655
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08149
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02212
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74252
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27666
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
BRD-K08308527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08091
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CREB1	ENCODE Transcription Factor Targets	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28238
levobunolol-3015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6959
RFX5	ENCODE Transcription Factor Targets	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.700377
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06738
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49178
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Toc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51097
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75578
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21829
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5513
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.47348
CRCGN015_MCF10A.WT.HP_24H:K15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01235
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52222
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09232
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943748
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5914
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88455
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23368
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52065
Brain Lower Grade Glioma_LGG_TCGA-DB-A64U-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6411
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19857
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-136	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01727
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91721
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.37961
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08149
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36286
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3853
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17666_KO_Smad2/Smad3_SRP137054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.65686
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92371
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09113
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10953
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852468
ornidazole-5064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
calcium folinate-3442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37584671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00542
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92544
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98888
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1712
Hyaline inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0678
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886253
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929779
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15292
HT1197	DepMap CRISPR Gene Dependency	1.0	4.60963
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7245
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP3	CCLE Cell Line Gene Expression Profiles	1.0	1.67076
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3183
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9652
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06497
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5145
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33856
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOBOX	JASPAR Predicted Transcription Factor Targets	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9458
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00991
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44239
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25636
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37075
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39235
PMC6122955-elife-33947-supp2.xlsx-NY8_v_NY15_DE_Bru-seq-HNF1A-regulated_genes_Bru-seq_after_shRNA_in_NY8_or_NY15_cells_-_related_to_Figure_7A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06706
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23355
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24507
CHD1	ENCODE Transcription Factor Targets	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23897
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54725
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32759631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63996
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07521
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76736
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chloroplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54727
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05424
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07291
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01639528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60205
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12321
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29717
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab10_KDM5C-KD-up-DKD-rescued-Table_10_Up-regulated_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31562
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K69269694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03329
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211267_1_v_0_trim21_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.17464
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927298
BRD-K16643911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70085
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66904
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31634
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07091
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.841027
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51172
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907508
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960488
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76613
Notochordal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24325
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51047
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11772
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4242
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61819
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134785
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910759
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269867
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40981
HNF4G	ENCODE Transcription Factor Targets	1.0	null
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
hsa-let-7i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7993
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2631
BRD-K65257143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35874
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38372
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71597
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Multiple Myeloma	CTD Gene-Disease Associations	1.0	1.11639
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45387
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21964
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
Perturb_1451_KO_Akirin2_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34901
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057242
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922875
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6453
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10078
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CFL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057533
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843553
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29234
DMRT1-21621532-FETAL-OVARY	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	3.90785
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2456
Protein of unknown function DUF1632, TMEM144	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49047
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28483
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21547
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14735
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4777-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4500	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03243
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07116
Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41736
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8419
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23625
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92008
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15107
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51913
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39412
hsa-miR-1269	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K52259096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09776
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86375
NR2F2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17987
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18647
GSE186810,GSE186813_3_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4305
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95409124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89603
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88026
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13009
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18814
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1765
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25905
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48268
BRD-K33400588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43453
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7192
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966544
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12538
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21038
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06238
trastuzumab_homo sapiens_gpl570_gse15043	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23905
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02363
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15496
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16166195-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42263
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0199
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04184
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17492
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46042
PMC9170821-JCMM-26-3183-s001.xlsx-Macro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49755
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64583
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08276
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29327
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67955
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00168
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15032
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913017
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940646
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977505
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14315
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18871
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93806
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
MFE296	DepMap CRISPR Gene Dependency	1.0	3.45431
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11659
GSE243199_1_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5336_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.64964
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61819
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A673	CCLE Cell Line Gene CNV Profiles	1.0	1.79016
GSE239898,GSE239899_1_v_0_hiltonol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.10907
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.471609
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35975
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31442
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27163
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	3.42742
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41221
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7149
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80391
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45307
Dot1l_DELETION_GDS4295_426_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 3 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36286
chr4_158147172_A_G_b38	GTEx eQTL 2025	1.0	1.70136
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.826639
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.95124
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.213322
Poisoning	CTD Gene-Disease Associations	1.0	1.05163
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060251
liminal part of alar r1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31442
hsa-miR-586	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3715
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.009
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30994
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38673
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02858
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5325-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6909
HCC2998	DepMap CRISPR Gene Dependency	1.0	4.40224
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MERO14	DepMap CRISPR Gene Dependency	1.0	3.81982
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29862
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51514
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Macro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41046
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.67912
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843541
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21613
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80641
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46627
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17916
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845603
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6446
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pain	CTD Gene-Disease Associations	1.0	1.02746
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69742
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.29072
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02212
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.1485
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0046
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10463
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Enterocyte progenitor cell_Small intestine_Human	CellMarker Gene-Cell Type Associations	1.0	null
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40293
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883568
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.852147
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98588
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.03419
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05644
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lidocaine (hydrochloride)_HEC-1-A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00833041
Fatty Liver	CTD Gene-Disease Associations	1.0	1.55206
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	-1.0	-0.928972
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01243
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943946
ZNF263	ENCODE Transcription Factor Targets	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.16446
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08272
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55425
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16164
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58195
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70069
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.05423
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3421
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22361
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15992638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27089
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12455
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52461
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12739
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9739
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70992
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9395
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955157
citalopram-4377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04573
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29679
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1552
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75783
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064422
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945953
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11408861-mmc2.pdf-11-TFCP2_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00437
HCoV-EMC2012_3Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.54272
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151119_2_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8369
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.01143
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0882
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935611
Heart Diseases	CTD Gene-Disease Associations	1.0	1.03976
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49108
NOS1	DepMap CRISPR Gene Dependency	1.0	2.26448
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827743
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skin	HPA Tissue Protein Expression Profiles	-1.0	-1.32077
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06804
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.582
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1361
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63104
17150101-TableS1g	GeneSigDB Published Gene Signatures	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22475
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28425
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00591
GTEX-NFK9-1226-SM-3LK79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993108
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
WAOSEL	DepMap CRISPR Gene Dependency	1.0	4.21248
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906562
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.40052
FOSL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41384
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86044
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13131
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40645
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13784
NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.30812
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10605_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.9156
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09235
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35788
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01687
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03127
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97732
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36394
GSE89569_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anabasine-6774	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14216
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06658
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842517
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13553
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77661
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	2.04845
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891504
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65442
E2F6	ENCODE Transcription Factor Targets	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08704
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5542-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42061
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40867
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51938
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04661
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
FGFR1HighNME5- epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01496
BRD-K15739647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00155
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15255
ozagrel-2942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44959
BRD-K85475457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06097
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4721_KO_Setd5_SRP117752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.38706
CRCGN014_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21519
DU145	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89642
SKNMM	DepMap CRISPR Gene Dependency	1.0	2.05104
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.30383
MYB	ENCODE Transcription Factor Targets	1.0	null
BRD-K16432886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46597
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMG-I	GDSC Cell Line Gene Expression Profiles	1.0	1.64539
BRD-K31230200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00241
GTEX-XUW1-1326-SM-4BOO1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825148
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70183
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_2_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	4.40502
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93668
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.367
STAT5A	ChEA Transcription Factor Targets	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04432
MET_knockout_247_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.66013
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.94896
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.565
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1147
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17251_KO_Il17ra_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.27285
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71767
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28078
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.69384
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887807
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41310621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05151
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14726
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
difenidol-2374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4981
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856627
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3707
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07835
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16775
H413	DepMap CRISPR Gene Dependency	1.0	3.82906
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2007
MCF7_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134109
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31442
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11113
EGR1	ChEA Transcription Factor Targets	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31812
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09803
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.94353
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H661	GDSC Cell Line Gene Expression Profiles	1.0	2.02589
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58224
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lobelanidine-2897	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88524
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
LU65	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57645
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACHN	GDSC Cell Line Gene Expression Profiles	1.0	1.97992
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.39685
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07326
hsa-miR-2117	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959453
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896336
BRD-K16633334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15512
5253409-961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2277
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841269
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28354
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52729
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60219
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40206099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22682
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18502
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58913
PMC8752721-42003_2021_2991_MOESM4_ESM.xlsx-Fig3_E2F2-gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
LIN7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94483
Perturb_7002_KO_Acadl/Acadvl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29334
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15279
methoxsalen-5007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7787
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07516
Brain Lower Grade Glioma_LGG_TCGA-HW-7495-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbamazepine-1847	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.01868
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5934
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02428
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8056-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70885
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5243
lateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08319
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849807
SNU119	CCLE Cell Line Gene Expression Profiles	1.0	1.37871
Perturb_12062_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11864
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.49618
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80169
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45284
Perturb_14865_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.9753
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5964
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832483
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03382
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64203
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03182
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82956
sox4_16636670_acc3_lof_human_gpl96_gds2193	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.541473
JHOM2B	CCLE Cell Line Gene Expression Profiles	1.0	1.49172
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49345
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2938
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.24
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935315
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2126
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45742
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919631
Occipital pole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80399
BXPC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76582
Prostate adenocarcinoma_PRAD_TCGA-EJ-5497-01A-02R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040293
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01906
BRD-K34595206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61485
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27946
GSE143782_6_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34054
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21427
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.702
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29321
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897505
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14684
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862207
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02504
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.835087
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212523
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997379
BRD-K73497584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12453
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10162
proglumide-2363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0591
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28367
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961429
PML	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.00164
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850832
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21601
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05604
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06607
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014413
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8142
BRD-K05070188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38061
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37458
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137914_2_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0465
Venous Thrombosis	CTD Gene-Disease Associations	1.0	1.09471
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65222
BRD-K31589685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66709
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.501396
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04395
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11093744-41592_2024_2172_MOESM3_ESM.xlsx-ELP-genes_NR5A1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62049
probucol-4666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1118
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.976135
FIZZ2_KO_GDS4902_408_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32609
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	3.01703
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1987
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58268
BRD-K28135985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38462
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980783
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953429
PSS131R	DepMap CRISPR Gene Dependency	1.0	5.43846
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937928
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868042
JVE015	DepMap CRISPR Gene Dependency	1.0	2.68842
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11465
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
pyrimethamine-1474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923046
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909898
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28189
NCIH1838	CCLE Cell Line Gene Expression Profiles	1.0	1.63394
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991673
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06207
AG-013608-6395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42378
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
notochordal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3952
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
ATP5F1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02017
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870157
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252857_2_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18895
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82657
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21324
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54716
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0668936
GTF2B	ENCODE Transcription Factor Targets	1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25445
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.068
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14116
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2805-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39644
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82788
HCC2998	GDSC Cell Line Gene Expression Profiles	1.0	1.82772
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08667
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05043
Memory Disorders	CTD Gene-Disease Associations	1.0	1.23616
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39193
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17581
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15163
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21583
hsa-let-7d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
spiramycin-3419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25611
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21911
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29469
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06157545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08783
Perturb_12234_KD_STAT3_SRP081918	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.2676
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.69952
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05408
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1761
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12652
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80981
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.44927
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28541
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946512
capan2	HPA Cell Line Gene Expression Profiles	1.0	1.09602
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19638
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22869
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07985
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26422
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27009
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1L0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.610305
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35154
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904372
RAD21	ChEA Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15906
GJC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049176
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49265
lm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
pargyline-7016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
L-428	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72246
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1974
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
foliosidine-6057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.97296
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
t30-blood-rna_male_2w	MoTrPAC Rat Endurance Exercise Training	1.0	1.79237
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6578
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2683
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831177
BRD-K19225848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15781
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.08369
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83959
PMC6122955-elife-33947-supp2.xlsx-NY8_and_NY15_HNF1A_binding-HNF1A_binding_status_for_genes_differentially_expressed_in_NY8_and_NY15_cells_-_related_to_Figure_7B_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11553
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14731
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16005
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.921773
luteolin-3379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11865
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97433
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17034
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850015
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.867766
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844428
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03573
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
gibberellic acid-2910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43274
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35092
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09862
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9971
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01275
Perturb_6999_KO_Acadl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.9626