association dataset threshold value standardized value Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078257 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.035 SKBR3 CCLE Cell Line Gene CNV Profiles 1.0 1.70049 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4846 496100397_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.36144 DNAJC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73808 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16656 esrra_19901197_kidney_lof_mouse_gpl1261_gse16623 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.602064 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9113 posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13132 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1937 CCLE Cell Line Gene CNV Profiles 1.0 1.68529 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.27151 HO-8910 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.874 cingulate gyrus, retrosplenial part, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.91031 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TE-10 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 COLO205 DepMap CRISPR Gene Dependency 1.0 2.21372 Field CA3, stratum lucidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37434 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.809 r5 part of A5 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14786 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100393_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14098 hsa-miR-3065-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4335 inner SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32885 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03592 ZSCAN31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30356 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4689 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vascular endothelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03873 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.43408 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22097 KATO-III cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.978 Anterior cingulate area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29376 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67896 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04847 Anterior cingulate area, ventral part, 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75591 nucleus of the diagonal band, left, vertical division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31683 cuneus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01565 FOXA1 ENCODE Transcription Factor Targets 1.0 null AR-21572438-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44062 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2746 PTPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14639 GSE176008_4_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null HOP-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null overexpression GeneRIF Biological Term Annotations 1.0 null HOXD10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9488 NCIH1105 CCLE Cell Line Gene Expression Profiles 1.0 2.05428 HCC1897 CCLE Cell Line Gene CNV Profiles 1.0 1.66031 cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049864 HCC95 CCLE Cell Line Gene CNV Profiles 1.0 1.98654 PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53 Rummagene Transcription Factor Associations 2026 1.0 null 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901541 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17486 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31597 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68784 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054091 Retrosplenial area, lateral agranular part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.587 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.921817 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r4 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2861 intermediate stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07214 LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05173 JHH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.49038 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.152 urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833812 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864166 endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.159291 Hippocampal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01754 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85239 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14786 hsa-miR-4423-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null paracentral lobule, posterior part, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.15551 NCIH146 CCLE Cell Line Gene Expression Profiles 1.0 3.40793 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.35706 ZFP62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46573 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8525 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Squamous Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4462 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70477 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.60809 Oral cavity cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.351 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2107 RDES CCLE Cell Line Gene CNV Profiles -1.0 -1.34872 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3872 periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66908 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849588 Oral epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.176222 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.946476 A3KAW CCLE Cell Line Gene Expression Profiles 1.0 1.68495 artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.067111 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5807 OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.853172 Carcinoma, Signet Ring Cell DisGeNET Gene-Disease Associations 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null HOXC10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.876 SNU1033 CCLE Cell Line Gene Expression Profiles -1.0 -1.62438 Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05837 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64965 NCIN87 DepMap CRISPR Gene Dependency 1.0 5.64565 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.991502 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130401_4_v_0_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 layer 5 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59841 ZBTB22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84917 extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null mantle zone of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28718 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.980542 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21639 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4333 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.81902 RH-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72453 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5889 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 Zfp36l2_deficiency_GDS3574_153_mouse_E14.5 fetal liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.72074 layer 6 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69739 MTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23855 r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05029 occur GeneRIF Biological Term Annotations 1.0 null Nucleus x Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.41619 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070589 ZFP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79605 hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.130962 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2995 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.840165 Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.0204 REL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46616 KMM1 CCLE Cell Line Gene Expression Profiles 1.0 1.96681 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.09068 LC1SQSF CCLE Cell Line Gene CNV Profiles 1.0 1.85037 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062096 possibly GeneRIF Biological Term Annotations 1.0 null invasive GeneRIF Biological Term Annotations 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094098 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6812 Perturb_3907_KO_DUSP6_SRP229874 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Connecting tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.985 superficial stratum of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26327 SARS-BatSRBD_Day7_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.9902 PACADD188 DepMap CRISPR Gene Dependency 1.0 3.32765 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null JAK1_knockdown_160_GSE37012 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.17207 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957464 Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6628 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCCSUP CCLE Cell Line Gene Expression Profiles 1.0 2.65492 Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68894 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14443 hsa-miR-374a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.5576 H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Appendage Adenoma DisGeNET Gene-Disease Associations 1.0 null posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.826472 hsa-miR-3685 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3118 DepMap CRISPR Gene Dependency 1.0 2.05589 SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04197 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.926139 GSE158632_3_v_5_oxyquinoline_human RummaGEO Drug Perturbation Signatures 1.0 null paracentral lobule, anterior part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28789 HCC33 CCLE Cell Line Gene Expression Profiles -1.0 -2.12069 GSE138019_1_v_2_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27306 GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2945 SH10TC CCLE Cell Line Gene Expression Profiles 1.0 1.54944 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9384 Secondary motor area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26647 superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34462 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.437 MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.78252 Medial geniculate complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52076 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9405 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32476 GPX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83119 CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61051 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMUGS DepMap CRISPR Gene Dependency 1.0 2.01598 IRF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30613 r3 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06841 GSE125219,GSE125221_5_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 RCM1 DepMap CRISPR Gene Dependency 1.0 3.02313 Kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08789 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.998275 Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liminal part of r3 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47065 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5786 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44062 amygdaloid complex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949147 TAL1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH2196 CCLE Cell Line Gene CNV Profiles 1.0 1.66058 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMBIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95519 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.97573 Hair follicle outer root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.839 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.45151 Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE115542_5_v_1_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null VZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84532 Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5647 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34246 medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06325 CAOV-3 COSMIC Cell Line Gene CNV Profiles -1.0 -3.18389 LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846353 Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18501 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01123 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33045 adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.290821 LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36591 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.30239 GAMG CCLE Cell Line Gene Expression Profiles -1.0 -1.45665 SORBS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87988 C99 DepMap CRISPR Gene Dependency 1.0 2.16324 inner CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.931318 DOV13 CCLE Cell Line Gene CNV Profiles -1.0 -1.69253 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976037 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.38785 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67142 GSE158197_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8658 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9278 kidney TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96832 Renal proximal tubule epithelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.877 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.4345 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.993869 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32909 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09999 GSE158197_5_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842198 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.047 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.0272 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dbtrg05mg TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.327 A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3767 GATA4-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8393 OCIM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.63806 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915686 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07623 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68753 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83359 OCIMY7 DepMap CRISPR Gene Dependency 1.0 2.1627 UACC893 DepMap CRISPR Gene Dependency 1.0 2.06793 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.40567 intermediate stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31539 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1209 DPRX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58998 primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30098 E2F4 ENCODE Transcription Factor Targets 1.0 null TIGD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15069 r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66908 GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.37738 GSE242290_3_v_11_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hsa-miR-3672 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 U-698-M COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040373 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.055555 P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4329 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Primary somatosensory area, trunk, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21394 mantle zone of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47002 EP300 ENCODE Transcription Factor Targets 1.0 null Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 Perturb_5949_KD_PTBP1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.91843 liminal part of r4 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2692 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01856 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899776 hsa-miR-1289 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.894563 lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73794 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1633 Prelimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17486 Cystic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 NCIH661 CCLE Cell Line Gene CNV Profiles -1.0 -1.41488 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2 Rummagene Transcription Factor Associations 2026 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057816 NCIH2170 CCLE Cell Line Gene CNV Profiles -1.0 -1.40893 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869215 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.057 A_CA_04_2009_4dayMOI-10^4_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.3288 outer SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903523 CCK81 DepMap CRISPR Gene Dependency 1.0 6.25728 SKOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93502 POLR2A ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22056 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null r3 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00707 Parabrachial nucleus, medial division, external medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34462 HOXB7-26014856-BT474-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2777-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158197_6_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 5 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51735 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65278 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null RXRA-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CAL78 CCLE Cell Line Gene Expression Profiles -1.0 -1.58747 layer 6 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92269 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50551 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15433 PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE ChEA Transcription Factor Targets 2022 1.0 null JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5717 496100630_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20336 VZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910339 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.102 PDCD2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46465 ZBED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40533 GSE158197_6_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE205163,GSE205164_3_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, ventral part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09753 CAL-85-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90019 PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56961 Secondary motor area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38484 pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.183581 precentral gyrus, left, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.968448 MG63 CCLE Cell Line Gene Expression Profiles -1.0 -2.37035 ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.52547 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210101,GSE210114_4_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52736 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20764 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2022 Primary visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33047 Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 6.92483 FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2 GSE153867_6_v_4_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null SNU489 CCLE Cell Line Gene CNV Profiles -1.0 -1.89712 MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6377 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38411 Urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superficial stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05303 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32946 Inferior salivatory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26812 intermediate stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55422 Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46692 Cystic Kidney DisGeNET Gene-Disease Associations 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.839549 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.842813 HK-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.877 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.824999 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20551 GSE166315_5_v_0_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.89954 Anterior cingulate area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62787 LC-1-SQ COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 GSE165274_1_v_2_poldip2_mouse RummaGEO Gene Perturbation Signatures -1.0 null intermediate stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06795 HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7193 496100546_TCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.06634 Superior olivary complex, periolivary region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06466 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.245 signet ring cell adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2356 PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0289 NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.121 medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27101 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29648 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prelimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3014 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4372 Superior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06701 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83589 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2769 inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21399 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09133 layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1259 brain endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.351856 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57797 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02664 HS739T CCLE Cell Line Gene Expression Profiles -1.0 -1.49843 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.58771 SAS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.127 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.824999 Gastric adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0168 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.974075 neuro2a BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23084 ZNF829 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42624 BECKER CCLE Cell Line Gene CNV Profiles -1.0 -1.42299 endothelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.399871 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.953002 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43205 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17152 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.82542 superficial stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01774 Dhori Virus_48Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.47559 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.4517 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12502 MFSD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06264 Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.043 TCF7L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58384 sublayer 6a of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87185 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.7017 liminal part of r2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23386 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068967 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13093 SJRH30 CCLE Cell Line Gene CNV Profiles -1.0 -1.74323 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6054 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957464 Esophageal squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.858 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040813 Myeloblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.675 GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 MLST8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88516 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85761 periventricular stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38945 Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.98042 hsa-miR-509-3-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE210101,GSE210114_2_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1307 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.837358 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1887 Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89962 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6046 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49948 striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.949427 hsa-miR-4701-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Brain - Amygdala GTEx Tissue Gene Expression Profiles 2023 1.0 1.85763 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977769 heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.157628 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02131 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.312 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.846313 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5421 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51735 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54766 GSE125219,GSE125221_5_v_8_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06163 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.19439 GSE199606_6_v_7_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null HSDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56883 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.75 SIGM5 CCLE Cell Line Gene Expression Profiles 1.0 1.5152 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 FOXN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4589 LI7 DepMap CRISPR Gene Dependency 1.0 2.78492 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.9848 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.7975 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34657 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.5485 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6526 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17695 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI6A DepMap CRISPR Gene Dependency 1.0 3.65641 r3 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39775 Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.88939 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039903 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25479 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87343 EmrE multidrug transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.202 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.946476 SCS214 DepMap CRISPR Gene Dependency 1.0 4.5363 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27353 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68117 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35836 SNU5 CCLE Cell Line Gene Expression Profiles 1.0 2.40575 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3504 Acute Myeloid Leukemia_LAML_TCGA-AB-2853-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97738 Renal distal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.997 wwox GeneRIF Biological Term Annotations 1.0 null NCI-H1975 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.619 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4006 UMUC7 DepMap CRISPR Gene Dependency 1.0 2.00321 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null HCC1187 DepMap CRISPR Gene Dependency 1.0 2.80715 GSE157594_3_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null ZNF354C JASPAR Predicted Transcription Factor Targets 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2778 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6048 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14695 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 GSE153867_6_v_3_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4638-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.3455 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.43126 E2F7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88793 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37818 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68631 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.05883 Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05174 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4663 IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4668 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.845425 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49139 HCE4 DepMap CRISPR Gene Dependency 1.0 7.05503 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4559 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.4839 Primary visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80881 SCARF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13478 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0067 Stomach cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.175 intermediate stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17483 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null sublayer 6b of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.58929 NCI-H1648 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53 Rummagene Transcription Factor Associations 2026 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9256 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30199 Goblet cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.308 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3728 Hmgn1_KO_GDS5010_407_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53345 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.21146 mantle zone of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49799 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07025 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU626 CCLE Cell Line Gene CNV Profiles -1.0 -1.40598 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2643 facilitate GeneRIF Biological Term Annotations 1.0 null GSE210655_3_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.91446 SKMEL30 DepMap CRISPR Gene Dependency 1.0 2.19196 cingulate cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49799 mantle zone of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30602 Colorectal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13148 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03386 hsa-miR-3134 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2732 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3739 Cortical amygdalar area, posterior part, medial zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60914 GSE138019_3_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.874683 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11274 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.8 mantle zone of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39775 C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.269 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RI1 CCLE Cell Line Gene CNV Profiles -1.0 -2.07251 Colorectal adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.01031 HOXB9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8561 NCI-H1304 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19323 TE4 CCLE Cell Line Gene Expression Profiles -1.0 -1.67498 FTH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01361 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38762 microvascular endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.196401 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79401 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14443 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.863444 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50557 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64485 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3689 HOXD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39323 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840998 ZNF215 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18187 mantle zone of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2692 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95789 U87MG CCLE Cell Line Gene Expression Profiles 1.0 1.35334 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57598 JHH2 DepMap CRISPR Gene Dependency 1.0 2.15231 intermediate stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48481 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9583 sublayer 6a of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53095 Renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66605 brain endothelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.17802 PDLIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83479 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.98803 Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21394 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061797 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915686 Signet ring cell adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.403 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68108 RAB3A_Mutation - D77G point mutation_GDS2483_697_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38557 Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SET2 DepMap CRISPR Gene Dependency 1.0 2.24156 SPTAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8119 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13231 GSE157594_0_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21352 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.0831 C1orf74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27437 blood vessel endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.172374 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.327 SMARCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29241 EPB41L5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91821 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100430_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08174 NCIH1648 CCLE Cell Line Gene CNV Profiles 1.0 1.50091 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12143 496100279_TCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.09378 GSE62292,GSE62295_2_v_0_col4a3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4046 hsa-miR-635 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GPR137 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9252 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06077 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.04547 hsa-miR-596 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16566 hsa-miR-3682-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.140752 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5344 mantle zone of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23386 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65288 superficial stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00866 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.864991 Intercalated cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.273 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0222 496100550_TCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.35732 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07792 hsa-miR-4260 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 HCC1806 CCLE Cell Line Gene Expression Profiles -1.0 -2.05061 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21123 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GRINA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37062 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70357 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.71385 SNU182 DepMap CRISPR Gene Dependency 1.0 3.9138 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51513 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09266 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3762 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF324B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38162 primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06011 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.05694 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -1.53234 human brain microvascular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.20378 PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53 Rummagene Transcription Factor Associations 2026 1.0 null VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.10642 LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09247 CLPSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61877 GSE153189_2_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1985 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.20726 496100473_TCx_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5464 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06911 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06713 carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.106668 r2 part of nucleus subcoeruleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22967 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.947996 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25315 temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3649 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03386 OCILY10 CCLE Cell Line Gene Expression Profiles 1.0 1.57952 Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80391 spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18341 Hair follicle bulge stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.058 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100667_TCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93082 IRF3 ENCODE Transcription Factor Targets 1.0 null SKOV3 DepMap CRISPR Gene Dependency 1.0 2.15768 EZH2 ENCODE Transcription Factor Targets 1.0 null SNU601 CCLE Cell Line Gene Expression Profiles -1.0 -1.63604 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.917815 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19365 hsa-miR-3667-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.297 lateral part of r3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2472 metastasis GeneRIF Biological Term Annotations 1.0 null TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43606 Kidney_CT1_Cortical Thick Ascending Limb Cell HuBMAP ASCT+B Augmented with RNA-seq Coexpression 1.0 null A_CA_04_2009_7dayMOI-10^6_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.01566 GSE157594_6_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04876 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.111077 ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33256 BMI1 ChEA Transcription Factor Targets 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54187 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TE10 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41246 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subcuneiform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.884684 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE85565_1_v_0_tcf21_human RummaGEO Gene Perturbation Signatures -1.0 null r4 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55293 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22596 496100544_PCx_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.47609 PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2137 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -2.50936 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6169 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.933087 sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.21972 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32621 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83359 intermediate part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47002 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.51027 CCDC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95118 central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.942986 RET_mutant_23_GDS3319 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.71304 PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1 Rummagene Transcription Factor Associations 2026 1.0 null Renal tubule epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.136 PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 Dorsal part of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16917 Prelimbic area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28454 GSE148252_5_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null molecular layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02058 T3M4 DepMap CRISPR Gene Dependency 1.0 2.25408 PCBP1_02_137 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.16993 posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66393 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null TE441T CCLE Cell Line Gene CNV Profiles -1.0 -2.5904 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 OAW-28 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8769 H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3945 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 SLC66A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92467 BATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24479 r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90019 r4 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31705 TE14 CCLE Cell Line Gene CNV Profiles 1.0 1.34228 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907014 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55605 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05352 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.50395 hsa-miR-4519 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.90053 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.905678 BBC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44711 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11748 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071123 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.055718 Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07165 BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Field CA1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1259 LANCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17634 GSE148252_2_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41397 Dorsal peduncular area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13124 cellular_component GO Cellular Component Annotations 2015 1.0 null r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52174 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-4418 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 microvascular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.197518 Brooke-Spiegler syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.967 HCC1588 CCLE Cell Line Gene Expression Profiles -1.0 -1.67073 CAPAN1 DepMap CRISPR Gene Dependency 1.0 8.81472 HOXC11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.178 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6678 496100462_PCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27045 HH CCLE Cell Line Gene Expression Profiles 1.0 1.74407 intermediate stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91934 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34483 Geniculate group, dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50434 Clear cell renal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.9507 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054524 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.1311 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03359 Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sebocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.331 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.983857 hsa-miR-4679 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01402 TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE153867_6_v_8_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null CORL88 CCLE Cell Line Gene Expression Profiles 1.0 2.17447 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 METTL21C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65522 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71589 NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TT CCLE Cell Line Gene CNV Profiles 1.0 1.35094 mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78087 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.213 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B_SEnh-Genes_containing_RING1B_EWSR1-FLI1_superenhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1667 GSE199606_6_v_7_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9669 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62025 Isl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.6651 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75055 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83359 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.157 ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.091 496100639_TCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25785 PIGQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81825 Secondary motor area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85587 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5193 PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.84898 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.3846 FOXM1-26456572-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gastric cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.797708 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FJX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3347 Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04352 KNS-62 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06029 ISTMES2 CCLE Cell Line Gene CNV Profiles -1.0 -1.7923 attenuation GeneRIF Biological Term Annotations 1.0 null PANC0327 DepMap CRISPR Gene Dependency 1.0 7.51774 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46818 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.88327 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35481 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GRHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1731 GSE210101,GSE210114_8_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1715 r5 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17282 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsal peduncular area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40964 CAL78 DepMap CRISPR Gene Dependency 1.0 2.11258 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04566 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90143 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3407 GSE158197_2_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 6b of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01754 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45828 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.844795 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83359 globus pallidus, internal segment, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.883961 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3041 Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FUS_02_155 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.55459 MBD3L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65319 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.36329 FOXG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.274 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2407 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0395 Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14689 superficial stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41246 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57595 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52236 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.913411 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TTLL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42308 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9453 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.53361 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7651 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03986 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r5 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48357 integral component of membrane GO Cellular Component Annotations 2015 1.0 null NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83359 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064939 NO10 DepMap CRISPR Gene Dependency 1.0 3.88631 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0921 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.87655 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65548 SNU46 DepMap CRISPR Gene Dependency 1.0 3.12294 MEL270 DepMap CRISPR Gene Dependency 1.0 3.04396 gastric cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.813144 dorsal lateral geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11501 small intestine HPA Tissue Protein Expression Profiles 1.0 1.41943 intermediate stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26218 JHU029 DepMap CRISPR Gene Dependency 1.0 6.83331 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01809 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6971 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.14304 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.22726 urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0545 A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.04467 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39543 A2058 CCLE Cell Line Gene Expression Profiles -1.0 -1.58559 Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19J-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.316 GSE131680_1_v_0_macroh2a1_human RummaGEO Gene Perturbation Signatures 1.0 null eclampsia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.23082 GSE210101,GSE210114_7_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Salivary gland adenoid cystic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.223 SCRIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82621 brain microvascular endothelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.24431 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27758 hsa-miR-4320 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KMS28BM CCLE Cell Line Gene Expression Profiles 1.0 1.7818 AR ChEA Transcription Factor Targets 1.0 null GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sweat gland benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 CLDN1_OE_GDS3510_31_human_CL1-5 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.999218 HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1406 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7601 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08694 Retrosplenial area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05948 SNU349 CCLE Cell Line Gene Expression Profiles -1.0 -1.45235 Mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902796 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.3159 hsa-miR-4434 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9268 Tongue cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.098 r2 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32265 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14645 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1789 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9132 hsa-miR-4717-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.03991 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -3.00119 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06325 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65827 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.26731 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35764 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1718 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7909 Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null GSE225656_2_v_3_tsc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11827 Cortical plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06163 CHCHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69447 D502MG DepMap CRISPR Gene Dependency 1.0 7.12615 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2746 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24451 FXYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90273 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47256 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19123 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.938491 TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.46423 A704 CCLE Cell Line Gene Expression Profiles 1.0 1.46982 GSE240386,GSE242143_1_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r5 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26001 FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null TNFAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92997 YWHAQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1702 Secondary motor area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60199 reticular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.47528 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14423 SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -2.07967 hsa-miR-4282 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2113 Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.0917 GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pre-eclampsia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.521502 External side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.559 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949147 hsa-miR-4516 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Lhx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4648 HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 2.56703 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25685 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8819 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.48205 CMAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9379 Anteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57595 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1884 KASUMI2 CCLE Cell Line Gene CNV Profiles -1.0 -2.11165 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6103 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.24442 r4 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3458 CTCF ENCODE Transcription Factor Targets 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.35 rectum HPA Tissue Protein Expression Profiles 1.0 1.41943 gastric GeneRIF Biological Term Annotations 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.875033 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6506 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4209 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24413 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39132 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.74272 SPI1 ChEA Transcription Factor Targets 1.0 null SNU503 CCLE Cell Line Gene CNV Profiles 1.0 1.95276 brain endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.321685 MAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38198 SNU1214 CCLE Cell Line Gene CNV Profiles 1.0 1.67384 PCI-30 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64965 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.52313 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1669 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8967 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8479 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054525 GATA3-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HOXD12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0312 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.63003 nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86159 r4 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38712 kato-iii cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.34315 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null BMI1-23680149-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.895294 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915686 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.96995 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.895083 Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100524_PCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.88942 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875231 BAG3 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4802-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058871 layer 4 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05671 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950286 SMCR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92235 cdkn1b_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl6246_gse27672 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.134483 Anterior cingulate area, dorsal part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04225 Tumor Progression DisGeNET Gene-Phenotype Associations 1.0 null Neoplasm Metastasis DisGeNET Gene-Phenotype Associations 1.0 null Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.369 hsa-miR-3065-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05339 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861867 r3 part of lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05303 Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07879 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35576 496100609_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63396 Neoplasm Of Skin With Adnexal Differentiation DisGeNET Gene-Disease Associations 1.0 null SARS-BatSRBD_Day2_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.68893 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRYBG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00492 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.844252 LS1034 CCLE Cell Line Gene CNV Profiles -1.0 -1.55709 hsa-miR-375 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67896 Field CA1, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17105 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8486 Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2746 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2746 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.16481 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893277 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2004 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.03482 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4727 4T1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.612 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3951 outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882608 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8964 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61938 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832309 Pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.162 OAW28 CCLE Cell Line Gene CNV Profiles 1.0 1.3515 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08994 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22097 Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JVM2 CCLE Cell Line Gene Expression Profiles 1.0 1.39633 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02686 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.228 PIK3CA_mutant_27_GDS4053 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.71482 Field CA1, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08192 Field CA1, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16134 Primary visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00715 Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33047 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68631 OAW28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32582 CAL-51 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.940557 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957464 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.834531 Mesothelioma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.679 septopallidal core nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43228 kidney GTEx Tissue Gene Expression Profiles 1.0 2.18987 SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9645 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mantle zone of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47065 COR-L279 COSMIC Cell Line Gene Mutation Profiles 1.0 null orbital frontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07668 QIMR-WIL COSMIC Cell Line Gene Mutation Profiles 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907014 DB CCLE Cell Line Gene CNV Profiles 1.0 2.25978 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null NCIH2029 CCLE Cell Line Gene Expression Profiles 1.0 1.6923 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.980972 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hsa-miR-4781-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 hsa-miR-501-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.928587 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 1.45212 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2703 pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02666 ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.183581 ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2355 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30633 layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28685 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240386,GSE242143_8_v_4_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE235644_1_v_0_fasn_mouse RummaGEO Gene Perturbation Signatures 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.919683 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.087 SETDB1 ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tmem207 GeneRIF Biological Term Annotations 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ABC1 CCLE Cell Line Gene CNV Profiles 1.0 1.47295 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -2.09045 Oral squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.308 NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.63126 Periosteal osteogenic sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.138 mantle zone of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24134 intermediate stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18962 layer 3 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09394 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53584 microvascular endothelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.05809 Sebaceous gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.033 RBM25_02_166 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.39232 RUSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62171 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00948 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130864_0_v_1_tincr_mouse RummaGEO Gene Perturbation Signatures 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0597 PRSS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28828 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -1.55154 GSE109285_3_v_2_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8596 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957464 P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Spinal nucleus of the trigeminal, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2998 Secondary Malignant Neoplasm Of Lymph Node DisGeNET Gene-Disease Associations 1.0 null NR3C1 ChEA Transcription Factor Targets 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 hsa-miR-4638-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Kidney_CT1_Cortical Thick Ascending Limb Cell HuBMAP ASCT+B Annotations 1.0 null SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91286 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7841 lung GTEx Tissue Gene Expression Profiles 1.0 0.970203 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07001 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07623 Spiradenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.607 SNU899 CCLE Cell Line Gene CNV Profiles 1.0 1.53604 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6834 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1578 PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null occipital cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30837 PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.49657 FOXP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.721 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97738 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.39159 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.85288 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35951 GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles -1.0 -2.32734 STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.13046 Cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02977 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.96241 PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00866 Renal Cyst DisGeNET Gene-Phenotype Associations 1.0 null superficial stratum of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21338 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.1552 hsa-miR-374b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837929 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9386 NB5 DepMap CRISPR Gene Dependency 1.0 2.15349 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.840366 DOTC24510 DepMap CRISPR Gene Dependency 1.0 2.2178 FOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.734 RUNX1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ISTMEL1 DepMap CRISPR Gene Dependency 1.0 3.12583 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03386 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21122 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.956674 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.6026 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89787 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46877 AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7036 Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.8384 PPARD_KO_GDS4320_619_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07072 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.69511 mantle zone of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24668 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5144 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 GSE158632_3_v_4_oxyquinoline_human RummaGEO Drug Perturbation Signatures 1.0 null GSE153443_1_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE207978_1_v_0_rai1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.353 GSE157594_5_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16656 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84048 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69968 Mucinous adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.514 RERFGC1B DepMap CRISPR Gene Dependency 1.0 4.3587 anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.94631 ANKRD16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85327 Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03435 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831658 A_CA_04_2009_7dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.64715 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.857512 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4782 Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 duodenum HPA Tissue Protein Expression Profiles 1.0 1.41943 r4 part of lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07072 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903771 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7653 PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA Rummagene Transcription Factor Associations 2026 1.0 null ICC4 DepMap CRISPR Gene Dependency 1.0 3.09813 PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null CAV1_Deficiency_GDS3551_559_mouse_Hearts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26413 vascular endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.171806 496100377_PCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54832 FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null signetring GeneRIF Biological Term Annotations 1.0 null 496100564_TCx_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30675 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60868 outer SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19294 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13045 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.331 ATP1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96586 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43029 A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.82309 brain cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.540188 Rectal adenocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.724 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null lm7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.701 496100336_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.56003 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, lateral agranular part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54787 TUBB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7536 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00337 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15738 superficial stratum of OCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30602 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02521 Apocrine sweat gland neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intergeniculate leaflet of the lateral geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62787 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12502 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31857 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.8815 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05313 IBA57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38436 cell part LOCATE Predicted Protein Localization Annotations 1.0 null EMC-BAC-1 COSMIC Cell Line Gene CNV Profiles -1.0 -3.18389 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 2.04055 SOX13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8719 SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -2.59674 NOLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81065 THTPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6788 Lung squamous cell carcinoma_LUSC_TCGA-46-6025-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 8305C CCLE Cell Line Gene Expression Profiles -1.0 -1.82838 layer 5 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00269 intermediate stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08257 MFE-280 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null COPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00017 layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05506 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0028 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.67253 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46786 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.957464 Kidney TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hsa-miR-4729 TargetScan Predicted Conserved microRNA Targets 1.0 0.127531 GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null ANKRD13B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67755 Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM253 DepMap CRISPR Gene Dependency 1.0 2.73783 lateral part of r4B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02084 CAV1_KO_GDS3551_366_mouse_mouse heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NFYA JASPAR Predicted Transcription Factor Targets 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW403 DepMap CRISPR Gene Dependency 1.0 3.9293 Photosensitive epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.594 PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05123 r3 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18962 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.25 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.70278 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32692 CTV1DM DepMap CRISPR Gene Dependency 1.0 4.05279 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08835 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Retrosplenial area, dorsal part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36901 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9019 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00929 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.5164 layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00419 NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54678 RT112 DepMap CRISPR Gene Dependency 1.0 3.17719 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.8421 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-2467-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null A388 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38381 vascular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.181031 primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927521 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Anterior cingulate area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.49924 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69046 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832309 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3532 CLDN1_OE_GDS3510_393_human_CL1-5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 5.65536 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFO21 CCLE Cell Line Gene CNV Profiles 1.0 2.28056 epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086205 HL60 CCLE Cell Line Gene Expression Profiles 1.0 1.84699 PARP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21377 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-412 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.101358 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.78129 lateral hypothalamic area, anterior region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18131 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9202 SNU475 CCLE Cell Line Gene CNV Profiles -1.0 -1.40153 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null gastric cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.170806 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9963 arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28006 KNS62 CCLE Cell Line Gene CNV Profiles 1.0 1.40714 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040043 NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 1.50467 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70888 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915686 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.829025 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69397 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE148252_5_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE240386,GSE242143_1_v_4_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05123 liminal part of the r5 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24188 A431 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.832309 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.929 superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00777 r5 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05123 KYSE-180 COSMIC Cell Line Gene CNV Profiles 1.0 2.08066 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.861088 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36628 HTK CCLE Cell Line Gene Expression Profiles -1.0 -2.69337 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02151 RBM34_02_141 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.70044 core of nucleus accumbens Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.982291 KMS20 CCLE Cell Line Gene Expression Profiles 1.0 1.68114 PR cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.508 CAOV3 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 Henles loop TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.799 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-642b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.860108 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93263 HOXC13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0503 AM38 CCLE Cell Line Gene Expression Profiles 1.0 1.49544 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.8094 GSE202284,GSE202289_3_v_4_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5431 PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null colo680n TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.176 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907014 temporal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34809 IRF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17794 HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0282 primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03188 mediodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.917933 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19233 GSE210885_3_v_7_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.969287 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06201 496100297_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.93521 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1858 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64485 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37873 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.962802 Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Renal carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 CIPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05607 superficial stratum of CCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49799 Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3094 Anterior cingulate area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70168 H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tongue cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.862 C32 DepMap CRISPR Gene Dependency 1.0 2.2483 stomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.347038 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 87.4277 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81293 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19323 Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null F36P CCLE Cell Line Gene Expression Profiles 1.0 2.19591 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956545 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5917 Polycystic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2438 inferior temporal gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.848817 GSE145639_7_v_4_adar_human RummaGEO Gene Perturbation Signatures 1.0 null superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.44138 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-509-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22299 H2AFZ ENCODE Transcription Factor Targets 1.0 null PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null ZFP37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48938 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.358 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15384 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.1385 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42953 Renal artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.66 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07786 GATA3_01_347 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60622 retromammillary area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08351 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null EPOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96372 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56256 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.8088 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.947297 DDRGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.471 dorsal pallium/isocortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09744 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSTA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3277 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null