association	dataset	threshold value	standardized value
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08366
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02925
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07092
Perturb_9565_KO_Cdx2_SRP149724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60949
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33172
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.2114
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.53651
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03517
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93336
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71863
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56035
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96753
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76441
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91998
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.5313
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.69021
hsa-miR-1202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1645
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979151
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34252
C99	DepMap CRISPR Gene Dependency	1.0	2.88508
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75817
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32883
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10639
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.876772
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2212
superficial stratum of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66839
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03892
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38564
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0455
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864893
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12584
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69217
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02869
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72092
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66422
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01794
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39482
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	0.876772
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3294
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887022
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62509
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01176
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35123
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47785
hsa-miR-3653	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01833
BICR31	DepMap CRISPR Gene Dependency	1.0	2.57127
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
medial part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25126
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34724
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.05263
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14536
AR-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62421
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76681
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14515
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4584
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38565
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86374
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09874
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50583
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8621
SET2	CCLE Cell Line Gene CNV Profiles	1.0	1.38916
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91999
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09795
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10639
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71757
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11535
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30964
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70035
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03188
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46389
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78733
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31388
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23104
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64252
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
SJSA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43518
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_14659_KO_Insm1_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0656
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37002
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.34829
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.47018
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37573
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10582
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36208
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48071
H2BK120ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14136
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06729
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82477
Perturb_4969_KO_Setdb1_SRP226379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.403
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46127
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09765
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27114
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90275
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.87625
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03239
Brain Lower Grade Glioma_LGG_TCGA-DH-5143-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	3.24078
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59951
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ChEA Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73556
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87808
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2977
SPRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52003
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05802
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7611
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53302
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.54107
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09544
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93081
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29118
LHX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61447
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4290621-1471-2164-15-S9-S7-S12.xls-Sheet1-HOXD-AS1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65777
hsa-miR-4691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07911
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86635
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93941
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882751
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57637
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05976
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97591
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10319
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.936098
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	3.27915
TTC549	DepMap CRISPR Gene Dependency	1.0	2.40688
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31927
hsa-miR-4260	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63955
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.23492
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03193
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17477
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34217
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19277
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4282
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.21245
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35252
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856554
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.21245
ORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77766
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37725
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42304
hsa-miR-4513	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5278
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96038
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46492
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25562
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7935
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05298
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32056
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03188
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17752
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14127
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968352
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43489
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951981
MKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59571
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0802
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
GSE77007_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.66
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8839
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
T-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00844
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
Perturb_14685_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7267
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842861
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85758
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95349
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Immune response to anthrax vaccine	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43129
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6982
Cutaneous leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
hsa-miR-4635	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33246
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2215
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.21245
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33313
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29269
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34591
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79003
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.876772
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2476
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4804
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34445
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64307
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3657	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51777
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89804
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9185
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12347
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.07914
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12753
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07005
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26779
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86724
TC205	DepMap CRISPR Gene Dependency	1.0	3.37493
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72036
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57928
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.96871
E2F4	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10935
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20238
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7273
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86556
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00805
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854814
Perturb_9740_KO_Kcnj11_SRP279345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.75707
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49622
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04536
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70713
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59774
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00152
hsa-miR-576-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29844
NEXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19775
ZNF143	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854814
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69985
hsa-miR-4263	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22756
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7925-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25225
Perturb_1692_KO_Prmt5_SRP059561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64033
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25908
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05681
EFO27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34471
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14665
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.06526
GSE114992,GSE114993_4_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05957
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.21245
PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2878
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44274
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40502
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1113
Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28736
CHAGOK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56793
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47753
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51406
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal plate of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5582
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	2.01217
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28767
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56931
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910674
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.6904
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11981
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
EW8	DepMap CRISPR Gene Dependency	1.0	5.46493
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.20684
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.212
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83228
Interphotoreceptor matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24219
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11211
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06832
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26894
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27187
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38901
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98101
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.14426
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80039
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02665
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55776
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11363
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34847
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
TE4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88101
EZH2	ChEA Transcription Factor Targets	1.0	null
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76995
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09325
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
mantle zone of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34006
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66409
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35451
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1442_KO_Stag2_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.6964
superficial stratum of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98499
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27467
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.70333
CAPAN1	DepMap CRISPR Gene Dependency	1.0	3.17405
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80959
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52385
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891058
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92601
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70833
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.46188
MSTO211H	DepMap CRISPR Gene Dependency	1.0	4.71366
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	11.1542
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6788
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
TXNDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41144
TMEM102	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96744
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
Thyroid gland adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09118
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04321
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73841
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0714
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02882
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.54021
MM160113	DepMap CRISPR Gene Dependency	1.0	5.49219
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25502
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01871
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2601
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43245
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11378
PHF8	ENCODE Transcription Factor Targets	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.876772
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58596
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48502
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07681
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60822
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07049
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824833
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
PMC9314667-Table_1.xlsx-Regulons-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06926
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VK-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63763
hsa-miR-199b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61918
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.186
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1393_KO_Rad9_SRP214104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.31046
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39086
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32181
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06658
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07507
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68542
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53228
RGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83904
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.91193
basal plate of p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24452
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNRC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84361
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05265
RGL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45747
ESR1	ENCODE Transcription Factor Targets	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05937
hsa-miR-653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35122
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17983
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51535
SNU1544	DepMap CRISPR Gene Dependency	1.0	7.42047
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895151
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60558
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40718
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1283	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77075
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08735
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05667
SOX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72425
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838837
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24013
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93644
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSC39	DepMap CRISPR Gene Dependency	1.0	2.1943
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39445
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2253
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41611
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945997
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31203
abnormality of the hair	GWASdb SNP-Phenotype Associations	1.0	0.268831
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858801
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00088
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81476
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0558
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.11119
GET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91424
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43193
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88365
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01551
JUND	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886821
OSC19	DepMap CRISPR Gene Dependency	1.0	2.67022
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60548
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29846
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.118
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30392
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_14674_Mut_GCK_SRP089943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.0607
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11357
PMC9052432-szac008_suppl_supplementary_table_s1.docx-11-POU3F1_1_POU3F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05869
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2377
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20238
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.76017
SAP30	ENCODE Transcription Factor Targets	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14227
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DACT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15857
Perturb_6829_KD_CDK11_SRP156201	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.7007
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5511
MFE296	DepMap CRISPR Gene Dependency	1.0	2.33419
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04512
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04764
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07992
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09325
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893338
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7804
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_5387_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.35328
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18655
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25373
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69776
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64373
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.889952
hsa-miR-4723-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74845
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856707
mantle zone of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25222
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1745_KO_Tet2/Tet3_SRP063091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.1765
GSE135400_1_v_0_kdm1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.11646
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34606
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NCIH441	DepMap CRISPR Gene Dependency	1.0	4.14387
GAPDHS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46245
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42892
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45747
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5896
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0547
GSE180200,GSE180201_12_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35904
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3871
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40154
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07941
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46127
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3059
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65849
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08922
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03188
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0204
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42542
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06728
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94251
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.912024
brain	GTEx Tissue Gene Expression Profiles	1.0	0.838512
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42839
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_14796_OE_Mycn_SRP094656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.42912
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03833
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01843
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.3126
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.12429
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25041
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86538
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886821
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26441
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58298
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14335
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32132
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.5303
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09343
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877665
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45842
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30832
ROS50	DepMap CRISPR Gene Dependency	1.0	2.58708
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835998
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.090112
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13439
TINAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92033
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46127
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028646
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84187
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20923
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6183
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04874
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54727
Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
MARCKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27275
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82734
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	2.12375
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45314
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40E-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9608
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90909
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13192
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8653
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35839
PMC7791134__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34889
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31733
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3462
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46127
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
CCC5	DepMap CRISPR Gene Dependency	1.0	5.95843
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3843
EP300	ENCODE Transcription Factor Targets	1.0	null
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34492
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20238
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64825
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	0.910596
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028669
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35346
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3443
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17626
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16042
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.24781
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43227
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868433
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.43
TSPAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96924
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREBRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96022
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	2.18987
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63873
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81S-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32535
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96271
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10639
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24311
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876945
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94588
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51661
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10728
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59215
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23641
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08822
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62402
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68327
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89857
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849923
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95037
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879609
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.6254
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02669
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3101
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63412
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03699
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58306
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CYB5RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39249
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213219_2_v_3_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.54132
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00439
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7662-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pretectal tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57468
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3736
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25985
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86423
hsa-miR-1290	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
Cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12765
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126402_1_v_6_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17548
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
ETFDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18966
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28258
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.21245
Central nervous system tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36878
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896361
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873764
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
496100310_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07533
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30582
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.846975
hsa-miR-2115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46453
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47233
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5367-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.5093
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1786
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08096
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48332
Perturb_1753_KO_Stag2_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5098
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941857
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00804
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30757
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13613
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58582
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75182
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13903
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36486
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4838
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01456
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30301
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94307
TBP	ENCODE Transcription Factor Targets	1.0	null
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34591
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.00686
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
TOP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35777
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	8.47433
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHLA90	DepMap CRISPR Gene Dependency	1.0	2.86997
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1713
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34021
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7147
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25369
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
quetiapine_mus musculus_gpl1261_gse45229	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38503
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09935
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30278
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.876772
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824492
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845147
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5678_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
hypoparathyroidism-deafness-renal disease syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35062
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37946
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
ZNF708_01_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.87549
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11971
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03406
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906358
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2658
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33946
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04698
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22167
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67323
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11643
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.96094
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25953
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14018
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43233
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54858
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14021
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
alopecia	GWASdb SNP-Disease Associations	1.0	0.769078
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48357
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50629
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937981
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52428
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86358
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78201
testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0091
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15775_OE_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.46396
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60954
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
PMC11091074-41419_2024_6684_MOESM1_ESM.pdf-4-ZNF493_ZNF493	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33156
L-363	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9052432-szac008_suppl_supplementary_table_s1.docx-11-POU3F1_POU3F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.94085
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17322
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825818
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	4.0263
icSARS CoV_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.07275
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44178
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4017
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10863267-12864_2024_10083_MOESM1_ESM.pdf-39-FEZF2_FEZF2	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0805
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32116
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887053
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
cone-rod dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
hsa-miR-1273c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886821
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51063
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARHGDIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65534
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79001
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1061_KO_Esr1_SRP087718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.54708
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63955
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.799
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49616
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10569
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00844
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06635
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14171
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.7617
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75348
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84461
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61391
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95495
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56095
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934439
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04874
COGN305	DepMap CRISPR Gene Dependency	1.0	4.97694
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38993
CEBPB	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-935	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82992
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16585
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20615
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DENR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43861
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26058
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44287
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62527
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06237
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26298
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996427
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91428
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30211
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97968
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9685
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53603
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52848
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
PMC3526356-supp_jem.20121387_JEM_20121387_sm.pdf-41-TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53388
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53565
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03133
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44561
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44423
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37062
preisthmic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06237
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941093
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29759
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.876772
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0664
CYREN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89022
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14464
ATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67878
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825818
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
beta-TC6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
mantle zone of AHy	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66906
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06237
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22295
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83518
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91934
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05298
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08019
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12753
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48874
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45142
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16467
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.2734
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59963
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70543
intermediate part of isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33897
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COGN278	DepMap CRISPR Gene Dependency	1.0	3.51851
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.6635
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
chr9_32724186_G_A_b38	GTEx eQTL 2025	1.0	4.19025
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
membrane part	GO Cellular Component Annotations 2015	1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18529
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8836
H4	DepMap CRISPR Gene Dependency	1.0	4.093
disease	GWASdb SNP-Disease Associations	1.0	0.024655
Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
H3K9me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.876772
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3143	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1275
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2323
integumentary system disease	GWASdb SNP-Disease Associations	1.0	0.146224
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.82119
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00844
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30626
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.098
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3685	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21547
vitamin c_mus musculus_gpl6246_gse19377	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05025
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69265
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1202
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39558
MXI1	ENCODE Transcription Factor Targets	1.0	null
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.51265
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NSMCE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33054
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02189
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38691
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61288
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1744
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0348
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47184
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43247
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16163
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75201
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20238
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957832
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86719
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79622
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36117
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.33465
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39295
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22205
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75107
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81634
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69418
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38959
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RETREG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93384
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5393
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	2.02529
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2893
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-586	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56951
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01865
LB2241-RCC	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06337
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20728
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1301
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17752
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14863
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
Perturb_7880_KD_INTS11_SRP266190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.25392
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21692
GABPA	ENCODE Transcription Factor Targets	1.0	null
TMEM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70171
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.04029
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	223.793
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951981
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93395
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77463
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.49122
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941647
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96428
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96225
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836525
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neurodegeneration with brain iron accumulation 2a	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10693
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81063
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20238
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987628
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867703
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873813
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4660	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.47375
Perturb_7459_KD_ICE1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.021
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.211
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.962
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	0.876772
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50524
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33501
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9482
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5744
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12604
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.974
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10589
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.989054
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85665
RIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5089
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08902
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79322
Mitochondrial isocitrate dehydrogenase complex (NAD+)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61475
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87942
Ectoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834969
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10639
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1300_KO_Foxp1_SRP158103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.95624
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3748
hypotrichosis	GWASdb SNP-Disease Associations	1.0	0.451302
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13159
LIPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85294
p1 part of the substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39332
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25341
SHMAC5	DepMap CRISPR Gene Dependency	1.0	2.16501
Perturb_3041_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0852
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
abnormal hair quantity	GWASdb SNP-Phenotype Associations	1.0	0.386013
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96392
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30099
NNAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.8069
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_8514_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30023
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4339
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0194
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.2758
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22784
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42776
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
MCMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64259
CHD7	ENCODE Transcription Factor Targets	1.0	null
Autosomal dominant nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.396
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.67519
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884015
mantle zone of p2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29593
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22246
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.876772
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898267
SNU1066	DepMap CRISPR Gene Dependency	1.0	2.27222
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027434
MORCPR	DepMap CRISPR Gene Dependency	1.0	2.28575
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47934
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27008
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
Isocitrate dehydrogenase complex (NAD+)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19387
TAF1	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32693
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3038
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91831
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7791134__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9423
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31408
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87953
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898866
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911777
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.3951
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963037
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93585
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04315
abnormality of skin adnexa	GWASdb SNP-Phenotype Associations	1.0	0.268831
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.395
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27398
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7433
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
werirb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Leukocoria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88611
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17068
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44635
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.47974
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61433
TDRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98516
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13273
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.9726
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16248
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01865
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896106
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Lung adenocarcinoma_LUAD_TCGA-55-8302-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28912
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71108
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18217
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00593
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05802
Lung adenocarcinoma_LUAD_TCGA-99-8028-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90003
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37053
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38733
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37888
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23604
TBPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94226
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.47261
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00628
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77711
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19815
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.12706
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04531
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81708
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90492
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
basal plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40691
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916125
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03464
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43353
hsa-miR-2355-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42525
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921805
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7618
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08787
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91481
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.093
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858311
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69595
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09935
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.32471
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55157
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856213
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30485
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52167
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7447
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05548
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.912716
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5248
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897851
Pancreatic adenocarcinoma_PAAD_TCGA-F2-7273-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36898
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78922
hsa-miR-4470	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1493
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95978
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32832
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28329
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02748
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05588
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0433
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.71
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.29391
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77788
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55283
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835998
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.792
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19421
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09704
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5136
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43625
BRSK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35871
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8588
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87683
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25459
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1239
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38894
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69299
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16541
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28202
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58645
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50593
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34457
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63393
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55287
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_8513_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8218
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58339
GATA2	ENCODE Transcription Factor Targets	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868051
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14374
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39655
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943883
Lung adenocarcinoma_LUAD_TCGA-38-4629-01A-02R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90016
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
m1 (rostral) midbrain tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4115
CORL279	DepMap CRISPR Gene Dependency	1.0	3.50484
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55319
C9orf72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85933
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5716
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43571
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969921
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963037
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04286
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05471
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87305
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15954
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65962
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45527
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23596
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8133
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6662
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B6-01A-21R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74739
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7622
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55287
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71165
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83062
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03039
endometrium	HPA Tissue Gene Expression Profiles	1.0	1.79925
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864465
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01967
ZNF705A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56583
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864708
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67673
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
prosomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25222
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13024
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01487
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.8115
KDM4A	ENCODE Transcription Factor Targets	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34031
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42067
TIMM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35715
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17752
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39841
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43615
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835314
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37635
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57939
H357	DepMap CRISPR Gene Dependency	1.0	2.48657
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881815
CTBP2	ENCODE Transcription Factor Targets	1.0	null
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06481
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
KE37	DepMap CRISPR Gene Dependency	1.0	2.28004
hsa-miR-1184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIHA	DepMap CRISPR Gene Dependency	1.0	2.84065
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59598
hypothalamic amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66772
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74122
TEAD4	ENCODE Transcription Factor Targets	1.0	null
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24C-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26102
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923944
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.67782
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47717
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62219
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	2.53364
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1051
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alopecia	GWASdb SNP-Phenotype Associations	1.0	0.666327
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.854926
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04168
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43233
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36743
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90549
E2F6	ENCODE Transcription Factor Targets	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835998
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81016
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970965
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42416
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39947
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.790592
CENPVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57608
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Postsynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11458
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05972
Neuropathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.554
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10075
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN3_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36859
RCHY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60952
MPV17L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67019
ESR1_ECC-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4646-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.2373
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06382
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05586
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
Differentiated thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.1688
Perturb_2934_KO_Msi2_SRP051590	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.59211
Perturb_4427_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.11035
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31411
ZNF436	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94366
Perturb_13045_KO_Tmem259_SRP195618	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.85226
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.00114
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54506
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16541
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87839
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4470	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930554
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56601
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.17954
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01123
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
hsa-miR-199a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95875
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37865
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0286
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.828
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.859
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973565
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44879
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4390-01A-02R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89321
DLX5_Deficiency_GDS4443_355_mouse_E10 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18956
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18012
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23011
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0779
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29796
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57051
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-550b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1667
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.21387
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74646
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07683
hsa-miR-224	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
intermediate stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51406
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1084
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3411
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.29504
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6713
BFTC905	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13055
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60566
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64066
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Macula lutea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKN3	DepMap CRISPR Gene Dependency	1.0	2.00217
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56132
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16248
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.246
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932729
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40722
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64144
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4275
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932871
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12584
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02294
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	77.6819
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.885046
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38611
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57273
RAD21	ENCODE Transcription Factor Targets	1.0	null
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49183
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4589
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.87688
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63935
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20795
hsa-miR-4782-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43665
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-193a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TXNL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16932
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.9986
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76135
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897851
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999222
RNF2	ChEA Transcription Factor Targets	1.0	null
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28544
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30544
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.468
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92898
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
Perturb_10338_KO_Nos3_SRP286435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53533
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50991
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96998
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98112
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84992
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12133
Perturb_1060_Mut_Esr1_SRP087718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7431
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40252
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67922
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94398
Apraxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36264
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9938
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23684
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61153
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67619
mantle zone of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20004
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPMI8402	CCLE Cell Line Gene CNV Profiles	1.0	1.47476
gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.062846
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0881
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-651	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0537
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07281
MERO82	DepMap CRISPR Gene Dependency	1.0	5.2762
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11462
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.41103
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14307
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08769
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS695T	DepMap CRISPR Gene Dependency	1.0	2.11116
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86187
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94011
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8225
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.55687
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2366
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.48974
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66905
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21519
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4157
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.86568
hsa-miR-579	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
hsa-miR-378g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33261
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5158
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.567
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23986
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18647
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	1.33897
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34492
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN4_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20228
CTCF	ENCODE Transcription Factor Targets	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898866
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.4102
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42283
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83116
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19992
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.40688
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94061
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5745
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06196
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3831
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7447
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00196
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.28298
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2718
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93456
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60268
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85483
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04203
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09764
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ARPE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28111
SNU213	CCLE Cell Line Gene CNV Profiles	-1.0	-2.93106
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07045
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77974
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860798
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61822
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34945
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2026
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30584
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84345
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05129
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32639
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52986
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908732
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74475
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45699
MEC1	DepMap CRISPR Gene Dependency	1.0	3.17994
USF2	ENCODE Transcription Factor Targets	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22635
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39808
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03276
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20786
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03077
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38288
Thyroid gland follicular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18974
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43192
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05835
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09042
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4436b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39847
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888238
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.2351
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12712
superficial stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71977
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.299
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.0051
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97056
ARPC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14833
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25839
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43479
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MHHCALL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54194
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0523
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.05
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
PSS008	DepMap CRISPR Gene Dependency	1.0	2.5661
HLA-DRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62541
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.1078
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48386
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14251
GSE203131_0_v_1_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74091
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.53877
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7389-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06075
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9298
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.6358
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
hsa-miR-380	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.591
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.25534
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82137
hsa-miR-145	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04074
Perturb_15566_KD_YAP1_SRP333272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.09304
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20321
EZH2	ENCODE Transcription Factor Targets	1.0	null
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4274
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46625
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36957
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28332
JURL-MK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.62313
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25712
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31366
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9156
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9613
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.4961
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37864
thalamic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24452
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71488
PANC0213	CCLE Cell Line Gene CNV Profiles	1.0	1.49016
TXNDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01372
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46435
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	4.37872
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19283
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930554
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18676
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17349
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09864
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.7433
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4444
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42464
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14136
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06541
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898866
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872366
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97456
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85154
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43191
Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1273	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.938409
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37019
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02091
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81775
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.757
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6736
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27069
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42081
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32324
hair disease	GWASdb SNP-Disease Associations	1.0	0.384598
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03951
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7181
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52444
hsa-miR-1249	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91251
superficial stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97404
Pars tuberalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.425
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05337
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95929
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04394
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34542
DDX31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28995
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.876772
RFXANK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37208
Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17819
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31154
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24072
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14727
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6031
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11837
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60459
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6396
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05937
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17635
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15757
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59119
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07179
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54424
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11093
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68934
HUPT3	DepMap CRISPR Gene Dependency	1.0	2.40628
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22665
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91003
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963037
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23977
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62012
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75679
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
Bipolar cell_Retina_Human	CellMarker Gene-Cell Type Associations	1.0	null
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06481
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25083
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11852
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
NCIH727	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30627
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23456
Perturb_1418_OE_Suv39h1_SRP150158	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08187
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71545
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89694
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832554
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2HX-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101239_3_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38211
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21228
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5392
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52444