association dataset threshold value standardized value periventricular stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04094 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07808 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07914 abnormal vitreous body morphology IMPC Knockout Mouse Phenotypes 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59153 ES5 DepMap CRISPR Gene Dependency 1.0 3.33005 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2121 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 55.6284 KML1 DepMap CRISPR Gene Dependency 1.0 2.59113 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null C1GALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36855 GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.705 RAB40A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99315 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.966 uterus GTEx Tissue Gene Expression Profiles -1.0 -1.01383 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sirt3_21397863_brown_adipose_lof_mouse_gpl1261_gds4058 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.513372 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064811 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.939 negative regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_17309_KO_Ddx25_SRP247988 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.12389 HNF4A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3157 TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100555_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.28135 496100488_TCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5414 PLIN5_OE_GSE44192_482_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TE4 CCLE Cell Line Gene CNV Profiles -1.0 -1.47599 FAM83E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85374 Cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1084 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3143 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.51146 shell of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38991 Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27347 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36871 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.494 ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0339 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null NR2C2AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19271 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.80374 COLO800 DepMap CRISPR Gene Dependency 1.0 5.24696 UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCC010 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16652 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.951 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04106 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1531 r5 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14944 HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14914 cataract MGI Mouse Phenotype Associations 2023 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.5423 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94351 NFYA JASPAR Predicted Transcription Factor Targets 1.0 null Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64234 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5704 A101D CCLE Cell Line Gene Expression Profiles -1.0 -2.08086 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01791 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.785 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48201 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03223 SACM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15189 496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.39302 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875748 OCIMY5 DepMap CRISPR Gene Dependency 1.0 2.20915 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0045 Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4096 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17376 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874787 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17217 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30017 T47D CCLE Cell Line Gene CNV Profiles 1.0 2.11013 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07002 Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28133 C32 CCLE Cell Line Gene CNV Profiles -1.0 -1.3971 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07914 Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9692 Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21662 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.38326 Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48997 Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36513 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.64236 HS571T CCLE Cell Line Gene Expression Profiles -1.0 -2.4374 SBC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null negative regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null CHP126 CCLE Cell Line Gene CNV Profiles -1.0 -1.63818 mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63843 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.45661 DUSP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49197 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6732 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5839 CARD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75335 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.65552 NCIH2073 CCLE Cell Line Gene CNV Profiles -1.0 -1.84576 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JT-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09934 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03593 M059K CCLE Cell Line Gene Expression Profiles -1.0 -1.48204 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041039 Primary motor area, Layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65084 KE39 CCLE Cell Line Gene CNV Profiles 1.0 1.78001 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43862 hsa-miR-298 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 layer 5 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08682 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.176505 Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPR20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37241 PKMYT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56874 Retrosplenial area, lateral agranular part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39558 OVCAR8 CCLE Cell Line Gene Expression Profiles 1.0 1.96601 PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.894179 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null prdm1_00000000_e9dot5_placenta_lof_mouse_gpl6887_gse39584 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.044639 Perturb_4981_KO_Kmt2d_SRP107208 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.738 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3278 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0651 Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1942 GSE198165,GSE198166_0_v_1_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null enlarged heart MGI Mouse Phenotype Associations 2023 1.0 null Abducens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17266 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92552 regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 5 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0067 LS513 CCLE Cell Line Gene Expression Profiles 1.0 1.39969 COLO678 CCLE Cell Line Gene CNV Profiles 1.0 1.4933 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13461 FBXO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16476 breast HPA Tissue Protein Expression Profiles -1.0 -1.45661 COV362 CCLE Cell Line Gene Expression Profiles 1.0 1.70478 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00694 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null sublayer 6b of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05096 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.48717 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051987 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054373 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42129 H2595 COSMIC Cell Line Gene Mutation Profiles 1.0 null AGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95411 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040856 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855785 Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18311 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11941 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40811 CUX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9779 r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37704 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7094 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33935 Seh1-associated complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.665 MAFF ENCODE Transcription Factor Targets 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910113 Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF Rummagene Transcription Factor Associations 2026 1.0 null PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.49558 periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42434 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100377_PCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.872 striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27122 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.106033 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7643 icSARS CoV_7Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.46271 NCI-H2405 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.935199 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04491 Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.1598 r9 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13606 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9405 BRCA1_DEPLETION_GDS3791_502_human_Hela cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11748 NANOGNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45501 PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5203 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2728 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 2.31656 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72461 HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1407 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3252 CAKI2 CCLE Cell Line Gene Expression Profiles -1.0 -1.53112 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2733 negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29561 496100512_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23151 SKMM2 CCLE Cell Line Gene CNV Profiles 1.0 1.33137 Ventromedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24802 GATAD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65653 SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -1.75476 Ventral premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73543 PHGDH_KO_GDS2874_125_mouse_embryonic head tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r4 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03834 azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.07908 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20217 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null body weights and measures GAD Gene-Disease Associations 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0703 SYCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13939 SNU886 CCLE Cell Line Gene CNV Profiles -1.0 -1.68751 CAKI1 CCLE Cell Line Gene Expression Profiles -1.0 -1.70257 Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94451 Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5507 NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3396 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.912 RB1_KD_GSE50532_592_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB7_01_169 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59186 FOXP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.26343 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13224 C2BBE1 CCLE Cell Line Gene CNV Profiles 1.0 1.35255 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.38824 PATU8902 CCLE Cell Line Gene CNV Profiles 1.0 1.34209 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.27608 dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.949158 TT2609C02 CCLE Cell Line Gene Expression Profiles -1.0 -1.6735 H3K9me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0195 Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.3107 SF172 CCLE Cell Line Gene Expression Profiles 1.0 1.60759 r3 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04029 mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10702 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29561 Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21049 hsa-miR-362-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 HEL CCLE Cell Line Gene CNV Profiles 1.0 2.00162 HARA CCLE Cell Line Gene CNV Profiles 1.0 2.79488 HMBOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4699 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61925 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.868 SEMA4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34241 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.45661 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 64.0621 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.4184 D-502MG COSMIC Cell Line Gene Mutation Profiles 1.0 null negative regulation of molecular function GO Biological Process Annotations 2015 1.0 null SNU738 CCLE Cell Line Gene Expression Profiles 1.0 1.58433 SRF JASPAR Predicted Transcription Factor Targets 1.0 null C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06871 hsa-miR-4291 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 HS822T CCLE Cell Line Gene Expression Profiles -1.0 -3.30829 XBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52227 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0426 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5156 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0276 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0196 Nodulus (X), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20232 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028773 Perturb_4979_KO_Kmt2d_SRP107208 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.74613 NSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 breast GTEx Tissue Gene Expression Profiles 1.0 1.02327 HDAC6 ENCODE Transcription Factor Targets 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35806 bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.845299 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29975 Posterior parietal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42129 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64578 spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.891798 abnormal vitreous body morphology MGI Mouse Phenotype Associations 2023 1.0 null thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.13062 Parasolitary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01084 SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.672 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SF126 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null DDR1_knockdown_169_GSE39207 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.55835 spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.294274 GSE191105_0_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92898 HAPSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53655 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04061 Hepatic Cirrhosis_Liver_GSE6764 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.96158 Nucleus of the solitary tract, gelatinous part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00396 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90057 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04392 A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12314 periventricular stratum of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41505 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45091 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.8722 TTC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9452 r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18497 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14944 NCIH727 CCLE Cell Line Gene CNV Profiles 1.0 1.46449 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.847 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01084 Ventromedial hypothalamic nucleus, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29528 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Alx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.7244 PELI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72011 EFO21 CCLE Cell Line Gene Expression Profiles -1.0 -1.57098 PL4 DepMap CRISPR Gene Dependency 1.0 12.2809 Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31652 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.208 Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.525 LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4766 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62953 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70987 Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3586 PPARA_KO_GDS3748_516_mouse_Livers GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56901 HCC366 CCLE Cell Line Gene CNV Profiles 1.0 2.08475 GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null KATOIII CCLE Cell Line Gene CNV Profiles 1.0 1.63732 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052212 496100349_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.79914 AM-38 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13497 SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8858 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66245 SUPT11 CCLE Cell Line Gene Expression Profiles 1.0 1.91455 PYGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71315 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97888 hsa-miR-548d-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.1748 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.82842 NEC8 COSMIC Cell Line Gene Mutation Profiles 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04333 intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10667 KMS21BM CCLE Cell Line Gene Expression Profiles 1.0 1.85766 Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06428 PCI30 DepMap CRISPR Gene Dependency 1.0 2.93222 negative regulation of phosphatase activity GO Biological Process Annotations 2015 1.0 null U266B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.7124 regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01592 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATOR2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.803 Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67952 NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4555 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49158 FXR MotifMap Predicted Transcription Factor Targets 1.0 null decreased prepulse inhibition MGI Mouse Phenotype Associations 2023 1.0 null mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44868 negative regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849671 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14678 biological_process GO Biological Process Annotations 2015 1.0 null EB-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25048 PPP1CA Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02037 Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11351 GATA3-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1397 Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32036 Dorsal column nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15891 GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03997 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36156 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.905716 H3K9me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null pancreas GTEx Tissue Gene Expression Profiles 1.0 1.8088 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00694 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874787 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEPG2 CCLE Cell Line Gene Expression Profiles -1.0 -1.66788 INA6 DepMap CRISPR Gene Dependency 1.0 2.05863 RIMS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36719 r2 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05343 AKT2_knockdown_44_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.76059 HS616T CCLE Cell Line Gene Expression Profiles -1.0 -1.46677 layer 4 of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12121 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82934 NCIH1573 CCLE Cell Line Gene CNV Profiles 1.0 1.7241 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.49844 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25198 negative regulation of dephosphorylation GO Biological Process Annotations 2015 1.0 null intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16046 DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17338 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.17223 Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.1579 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -2.27189 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50114 Fastigial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25443 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 regulation of phosphatase activity GO Biological Process Annotations 2015 1.0 null hsa-miR-548z TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57613 lateral part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29028 dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06628 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIC JASPAR Predicted Transcription Factor Targets 1.0 null RPMI7951 DepMap CRISPR Gene Dependency 1.0 2.13417 Perturb_5221_KO_Zfp57_SRP173610 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.97097 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6357 negative regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.54205 KMS21BM CCLE Cell Line Gene CNV Profiles 1.0 1.64655 ST486 CCLE Cell Line Gene Expression Profiles 1.0 2.52029 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.81564 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245175 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052212 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.6381 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.6523 KHM1B CCLE Cell Line Gene CNV Profiles 1.0 1.39852 RH30 CCLE Cell Line Gene Expression Profiles -1.0 -1.49526 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.83062 male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.740299 CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60829 hsa-miR-2276 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.264 spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12483 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4065 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF519 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75528 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54758 NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.70669 OCILY10 CCLE Cell Line Gene CNV Profiles -1.0 -1.4729 MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.4901 Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74973 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AKT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86097 Primary somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13278 NB7 DepMap CRISPR Gene Dependency 1.0 7.08237 RDES CCLE Cell Line Gene CNV Profiles 1.0 1.37506 hsa-miR-3180-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 FGD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35666 EGI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7858 Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.515 placenta HPA Tissue Protein Expression Profiles -1.0 -0.718945 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.874787 NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.56129 parathyroid gland HPA Tissue Protein Expression Profiles 1.0 1.54205 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3539 Ovarian mucinous neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.282 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.362 PEX11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5578 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.989377 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5761 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44912 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44918 ZNF684 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6744 Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF483 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16355 Body Weights and Measures dbGAP Gene-Trait Associations 1.0 0.190968 SUIT-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863501 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1401 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940547 AARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08429 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25214 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876637 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42744 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.707 Primary visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09211 periventricular stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05443 HUPT4 CCLE Cell Line Gene Expression Profiles -1.0 -2.11513 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6802 Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100387_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.84256 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 URGCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5021 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78062 PTK7_knockdown_185_GSE50138 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.02984 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0223 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7688 CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE176008_8_v_5_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null HSC-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17066 HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cellular_component GO Cellular Component Annotations 2015 1.0 null SNU-423 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06716 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29628 CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Inhibin B complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100342_PCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.09752 r8 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01434 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28604 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58896 H357 DepMap CRISPR Gene Dependency 1.0 4.18353 ventral premammillary nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44861 NCIH1792 CCLE Cell Line Gene Expression Profiles -1.0 -1.4677 SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2121 hsa-miR-3065-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.051305 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 43.3139 SCABER COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of molecular function GO Biological Process Annotations 2015 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.03988 nuclear membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.577999 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.41502 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847576 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053361 bladder GTEx Tissue Gene Expression Profiles -1.0 -1.01383 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8456 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ECC4 DepMap CRISPR Gene Dependency 1.0 3.19852 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.4066 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.572 KNS81 DepMap CRISPR Gene Dependency 1.0 4.52399 496100628_FWM_dementia_TBI_77_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40309 sublayer 6a of OCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0903 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05763 abnormality of cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.193759 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.49229 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.6046 duodenum HPA Tissue Protein Expression Profiles 1.0 1.54205 SCH DepMap CRISPR Gene Dependency 1.0 2.20293 Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74498 biological regulation GO Biological Process Annotations 2015 1.0 null CACO2 CCLE Cell Line Gene CNV Profiles 1.0 1.36835 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15203 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937561 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2134 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null HS870T CCLE Cell Line Gene Expression Profiles 1.0 2.24169 NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47489 small spleen MGI Mouse Phenotype Associations 2023 1.0 null PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL Rummagene Transcription Factor Associations 2026 1.0 null Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 central part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08334 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3372-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41366 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041929 SW948 COSMIC Cell Line Gene Mutation Profiles 1.0 null appendix HPA Tissue Protein Expression Profiles 1.0 0.878931 Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 integral component of membrane GO Cellular Component Annotations 2015 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21238 ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1155 ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18311 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9238 spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.910093 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.34632 hsa-miR-548aa TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92552 NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.78705 Anteromedial nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07999 terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03101 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.386179 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4695 GFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94978 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.64569 Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1231 periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13932 hsa-miR-4690-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 ETV3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9205 Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6882 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.51686 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4205 negative regulation of metabolic process GO Biological Process Annotations 2015 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1566 PGM2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47571 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67151 abnormality of transition element cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.275957 TOLEDO CCLE Cell Line Gene Expression Profiles 1.0 1.54158 cell part LOCATE Predicted Protein Localization Annotations 1.0 null chr11_123837329_A_G_b38 GTEx eQTL 2025 1.0 6.36502 dorsomedial nucleus, terminal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30522 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05429 Bed nuclei of the stria terminalis, anterior division, ventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05181 Type 1 diabetes mellitus_Thymic epithelial cell_GSE11 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.00788 Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5565 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 dorsolateral SC part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0697 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29765 LCLC103H CCLE Cell Line Gene CNV Profiles -1.0 -2.11426 U2904 DepMap CRISPR Gene Dependency 1.0 2.26123 regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31484 envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.10081 ETV5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5525 r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25885 Acute pyelonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29561 Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12505 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03279 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8971 r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13788 Primary motor area, Layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02328 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937561 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17217 Oleic acid (18:1n-9) levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 SUDHL5 CCLE Cell Line Gene CNV Profiles -1.0 -1.33854 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04491 enlarged heart IMPC Knockout Mouse Phenotypes 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057405 m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05763 496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.97777 regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null hsa-miR-3619-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 CERK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13949 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04976 496100566_FWM_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.54954 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null C8166 DepMap CRISPR Gene Dependency 1.0 2.99786 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.0301 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5816 GLYR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46262 small heart IMPC Knockout Mouse Phenotypes 1.0 null NCIH526 CCLE Cell Line Gene CNV Profiles 1.0 2.24777 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21254 BICR10 DepMap CRISPR Gene Dependency 1.0 4.72723 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041067 SHP-77 COSMIC Cell Line Gene Mutation Profiles 1.0 null BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25214 TNNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13726 Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19351 layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46742 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16302 U87MG CCLE Cell Line Gene Expression Profiles -1.0 -1.86144 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53921 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45091 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.97079 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1089 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3793 basolateral amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10654 abnormal freezing behavior MGI Mouse Phenotype Associations 2023 1.0 null CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.165 r9 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60906 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70706 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7763 Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95453 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048613 HCC2998 DepMap CRISPR Gene Dependency 1.0 13.8164 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.792 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5 Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52463 intermediate stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07145 medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6646 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11941 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9685 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHSA0011 COSMIC Cell Line Gene Mutation Profiles 1.0 null PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7531 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.2181 spleen HPA Tissue Protein Expression Profiles -1.0 -0.718945 Perturb_5143_KO_Ring1B_ERP008873 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.7641 Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14641 PFEIFFER CCLE Cell Line Gene Expression Profiles 1.0 1.77712 Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44586 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0863 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47702 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCO2 DepMap CRISPR Gene Dependency 1.0 2.55821 periventricular stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01402 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null OVSAHO CCLE Cell Line Gene CNV Profiles -1.0 -1.96808 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.4049 Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51409 cerebellum HPA Tissue Protein Expression Profiles -1.0 -0.936792 SNU-61 COSMIC Cell Line Gene Mutation Profiles 1.0 null Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.42364 periventricular stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14981 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2271 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 2.71777 nuclear envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.377354 EW7 DepMap CRISPR Gene Dependency 1.0 3.27969 lateral preoptic area, PO1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06098 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041773 male infertility MGI Mouse Phenotype Associations 2023 1.0 null Primary motor area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49344 intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14871 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21904 JDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18501 P12ICHIKAWA CCLE Cell Line Gene Expression Profiles 1.0 3.39522 A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.74449 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19225 KICSTOR complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.103 YAPC CCLE Cell Line Gene CNV Profiles 1.0 1.42173 CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-761 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 PATU8988T DepMap CRISPR Gene Dependency 1.0 4.23839 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07336 periventricular stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60957 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11874 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.27746 BDCM CCLE Cell Line Gene Expression Profiles 1.0 1.45026 SNU475 CCLE Cell Line Gene Expression Profiles -1.0 -2.42544 ICC3 DepMap CRISPR Gene Dependency 1.0 2.47332 superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18311 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2671 Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0459 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00694 stomach HPA Tissue Protein Expression Profiles 1.0 0.878931 Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07825 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.5157 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49158 NCI-H727 COSMIC Cell Line Gene CNV Profiles 1.0 2.15316 Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17217 GSE131377_4_v_2_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 4 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0426 r9 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31401 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09769 cerebellar nuclei of CbV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29437 Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.888 all GWASdb SNP-Phenotype Associations 1.0 0.028749 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11874 Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal heart morphology IMPC Knockout Mouse Phenotypes 1.0 null SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7825 PMP-22/EMP/MP20/Claudin superfamily InterPro Predicted Protein Domain Annotations 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60829 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848084 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2134 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14678 mantle zone of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01402 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4722 COLO205 DepMap CRISPR Gene Dependency 1.0 4.37491 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.307 CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null vagina HPA Tissue Protein Expression Profiles -1.0 -1.45661 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.7282 Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of iron homeostasis GWASdb SNP-Phenotype Associations 1.0 0.726078 abnormal freezing behavior IMPC Knockout Mouse Phenotypes 1.0 null Primary somatosensory area, unassigned, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76398 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.121672 MOV10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80999 WDR91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.56371 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.13145 regulation of cellular process GO Biological Process Annotations 2015 1.0 null ISTMEL1 DepMap CRISPR Gene Dependency 1.0 10.0551 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253578 496100314_HIP_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61904 organelle envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.109351 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23937 HT CCLE Cell Line Gene CNV Profiles -1.0 -1.66544 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.9018 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4502 OTX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12773 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2244 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56964 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.36939 LHFPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12934 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.257 TAL1 ENCODE Transcription Factor Targets 1.0 null ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1826 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.6829 ACTL6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99393 r7 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1884 Cardiomyopathy, Dilated_Myocardial tissue_GSE3586 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.61329 PPP1R1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10454 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03223 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.92613 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00733 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.974689 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848084 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51883 Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43636 RHJT DepMap CRISPR Gene Dependency 1.0 2.70461 GSE206870,GSE206872_3_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045427 endomembrane system COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.207794 KMRC2 CCLE Cell Line Gene Expression Profiles -1.0 -2.62687 regulation of dephosphorylation GO Biological Process Annotations 2015 1.0 null Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4379 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.405935 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25071 Protein phosphatase inhibitor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.791 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3985 layer 4 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0447 SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14138 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 medial (fastigial) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29311 HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94451 ventrolateral part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52799 FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86586 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.406 small spleen IMPC Knockout Mouse Phenotypes 1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67151 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.0741 CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06625 TE159T CCLE Cell Line Gene Expression Profiles -1.0 -1.76311 abnormality of ion homeostasis GWASdb SNP-Phenotype Associations 1.0 0.193759 abnormal heart morphology MGI Mouse Phenotype Associations 2023 1.0 null CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -0.718945 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.226 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.882 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41829 superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07716 TM9SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69191 mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18346 SW837 CCLE Cell Line Gene CNV Profiles 1.0 1.38878 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.25 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.37317 hsa-miR-214 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 regulation of hydrolase activity GO Biological Process Annotations 2015 1.0 null SKNSH DepMap CRISPR Gene Dependency 1.0 11.9746 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21895 bed nucleus of the external capsule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43335 Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2547 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98304 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16302 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847576 HT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09184 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.4444 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.14171 GSE206870,GSE206872_4_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Asthma_Epithelial Cell_GSE4302 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.06421 KLF5_KO_GDS3509_553_mouse_ES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13224 Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58687 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -3.21044 membrane LOCATE Predicted Protein Localization Annotations 1.0 null cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5705 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848084 SMC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24677 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37748 HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910113 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36513 intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25803 layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15238 HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -1.86844 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -0.718945 Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2778 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8255 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25071 NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary somatosensory area, barrel field Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1029 intermediate stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08356 Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37785 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12152 r7 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01909 periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13642 PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -1.45946 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849671 Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0318 Posterior parietal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05264 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0052 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.47711 SHI1 DepMap CRISPR Gene Dependency 1.0 4.60769 FEV JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4755 mineral metabolism disease GWASdb SNP-Disease Associations 1.0 0.392942 POLR2A ENCODE Transcription Factor Targets 1.0 null SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04491 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844229 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855785 LDB1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.039 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12891 ME1 CCLE Cell Line Gene CNV Profiles 1.0 2.00032 Arid3b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.5188 Serum uric acid levels in response to allopurinol in gout GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35893 SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847576 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30239 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50997 OCIMY7 CCLE Cell Line Gene CNV Profiles 1.0 1.38124 MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.50011 PCGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99894 E2F6 JASPAR Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRMT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62194 MEWO CCLE Cell Line Gene CNV Profiles -1.0 -1.33542 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04392 iron metabolism disease GWASdb SNP-Disease Associations 1.0 0.831584 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.6855 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Somatosensory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10471 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26153 ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.900008 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4383 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74973 NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null male infertility IMPC Knockout Mouse Phenotypes 1.0 null TIMM8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.052724 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 hsa-miR-409-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hsa-miR-548ac TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEP164 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93729 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42434 Primary motor area, Layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27347 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02916 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876637 JVM2 CCLE Cell Line Gene Expression Profiles 1.0 1.7864 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.432991 regulation of metabolic process GO Biological Process Annotations 2015 1.0 null periventricular stratum of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18801 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.02131 pancreas HPA Tissue Protein Expression Profiles -1.0 -0.718945 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95332 Secondary motor area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84171 EZH2 ENCODE Transcription Factor Targets 1.0 null negative regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99498 PFKP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91596 NB1 DepMap CRISPR Gene Dependency 1.0 2.17413 TRIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88835 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910113 peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38991 DU4475 DepMap CRISPR Gene Dependency 1.0 2.52209 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.665 JHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98064 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.6281 HS751T CCLE Cell Line Gene Expression Profiles 1.0 1.67611 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.01383 RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00844 cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01561 hsa-miR-587 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30226 small heart MGI Mouse Phenotype Associations 2023 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63076 WM983B CCLE Cell Line Gene CNV Profiles -1.0 -2.57584 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0556 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CS1 COSMIC Cell Line Gene Mutation Profiles 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12184 regulation of biological process GO Biological Process Annotations 2015 1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAB15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17886 DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64652 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.9399 decreased prepulse inhibition IMPC Knockout Mouse Phenotypes 1.0 null RIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06445 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58462 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30226 Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23221 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.7193 layer 5 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01307 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.0 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17217 Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42744 GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3307 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09769 PL18 COSMIC Cell Line Gene CNV Profiles -1.0 -3.24687 496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45033 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4661 Septic Shock_Whole blood_GSE9692 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.40159 Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.6369 A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.73332 SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -2.06002 primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274814 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPR162 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96946 IRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95357 membrane part GO Cellular Component Annotations 2015 1.0 null SK-LU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null LCLC-103H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39424 disease GWASdb SNP-Disease Associations 1.0 0.024829 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052454 small intestine HPA Tissue Protein Expression Profiles 1.0 1.54205 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59102 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41248 cataract IMPC Knockout Mouse Phenotypes 1.0 null Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47702 kidney GTEx Tissue Gene Expression Profiles -1.0 -1.01383 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.8818 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.471 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 2.24831 NUDT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2198 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07914 KYSE450 CCLE Cell Line Gene CNV Profiles -1.0 -2.00221 Inhibin A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.802 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.1889