association	dataset	threshold value	standardized value
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.827
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25319
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19103
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
IDUA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00676922
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12091
cell part	GO Cellular Component Annotations 2015	1.0	null
infected	GeneRIF Biological Term Annotations	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8578
spread	GeneRIF Biological Term Annotations	1.0	null
DACH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00450104
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2577
b95a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6722
RPMI-8402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518199
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54809
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
open	GeneRIF Biological Term Annotations	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05801
REL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564377
BRD-K38558166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2339
Serum Total Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
CRCGN009_HEPG2_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00884
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55195
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7053
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50078
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22008
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01102
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548914
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57801
ULK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056611
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890018
COL1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004378
BRD-K05653239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15182
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76466
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26022
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07434
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62507
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51833
Digestive cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.45213
TACR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535382
PMC7165319-3896263.f6.xlsx-List_of_AA_outlier_pool-AA_outlier_pool_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59486
A-CA-04-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31364
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47087435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48214
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48312
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056608
Perturb_6688_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.76054
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919827
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15077
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577377
Syncytium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
VAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72455
BRD-K43872193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04745
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
MALME3M	DepMap CRISPR Gene Dependency	1.0	3.17697
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9241
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44284
OCI-LY-19	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
SLC52A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608985
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73052
NCIH2122	CCLE Cell Line Gene Expression Profiles	1.0	1.47406
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15957
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.14088
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
CYB5R3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751012
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98794
BRD-K74095559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16223
TE9	CCLE Cell Line Gene Expression Profiles	1.0	1.6292
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95545
LIPF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513489
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869445
CTSE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057829
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21555
kidney	HPA Tissue Protein Expression Profiles	1.0	1.56518
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847457
BRD-K19540840_saracatinib_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926081
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139735
HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
C5AR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00810183
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08313
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8676
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61388138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37612
CRCGN015_MCF10A.WT.HP_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48583
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.998885
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31565
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057997
MSTO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00686363
SCUBE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00417261
hsa-miR-4517	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
20713713-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
SK-MEL-5	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
MLKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636518
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.45983
HEL	DepMap CRISPR Gene Dependency	1.0	3.16891
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GART	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681787
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831557
SNU1033	CCLE Cell Line Gene Expression Profiles	1.0	1.38782
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02799
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1866
SOX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26238
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
MON1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00641207
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880786
LHX8_Deficiency_GDS3254_600_mouse_Newborn ovaries	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67292
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44993
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2578
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39414
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23336
hsa-miR-4778-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17462
Perturb_6697_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.80648
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20362
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.72874
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1475
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12756
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1446
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34931
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
SCN9A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00667589
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00563
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63434
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.532
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837564
LAIR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00787473
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24708
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.30133
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97145
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
NFE2L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653956
BRD-K24259871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69291
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10855
LHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763197
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22467
Perturb_16785_KD_AMIGO2_SRP369776	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K42385001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50356
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8999
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22048
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	1.39867
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
CRCGN015_MCF10A_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05468
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2517
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45086
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01579
BRD-K42960858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1138
CHEK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0103567
GSE99687_3_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58091
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864342
KP-N-YN	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
SEA domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pocket	GeneRIF Biological Term Annotations	1.0	null
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K67503471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03911
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07795
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14161
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1007
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051935
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Eca-109 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63929
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44360367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41908
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95603
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76305
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20368
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48258
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.06034
16353136-Table3	GeneSigDB Published Gene Signatures	1.0	null
SP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07507
POU2AF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00665286
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22358
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50253
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67141
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-N87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37108
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59522
SNUC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47316
BRD-K71032892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22698
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126925
SLC1A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558614
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	2.24029
hsa-miR-4778-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2444
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66628
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
because	GeneRIF Biological Term Annotations	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964373
NCIH226	DepMap CRISPR Gene Dependency	1.0	5.6604
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02202
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26468
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.954314
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85551
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76112
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14363
BRD-K95553255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08225
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cognition	GO Biological Process Annotations 2025	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57568
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22467
NMCG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53294
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2087	CCLE Cell Line Gene Expression Profiles	1.0	1.3724
COV504	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12686
pioglitazone_mus musculus_gpl2897_gse8806	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PYCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554962
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.9221
metabolic process	GO Biological Process Annotations 2015	1.0	null
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90313
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04714
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.937195
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14997
GTEX-XMK1-2626-SM-4B65R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03532
MAP3K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00420953
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14575
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K55543534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71393
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58119
EEF1AKMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88084
BRD-K06431655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19259
IGLON5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632685
CL14	CCLE Cell Line Gene CNV Profiles	1.0	1.58034
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27004
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47746
TRAF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504101
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73141
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.437
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901469
GNAI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473795
GSE193258,GSE193259_5_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44987
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0093
central medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.939637
hsa-miR-802	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98209
Lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.32
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23316
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920876
LILRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0073733
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57334
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36928
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.09705
BRD-K54639145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89728
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7932
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
PANC0213	CCLE Cell Line Gene Expression Profiles	1.0	1.56752
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38208
SULT2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00491559
RHAG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00600354
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58577
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87988
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
KCNJ8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00560755
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.39243
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1125
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.108
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041654
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48879
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.4211
CANX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00933362
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04608
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.63085
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.647
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3963
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.020068
MGP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.011021
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0193
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87143
ITK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0061869
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69505
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948111
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909024
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64307
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NHA	CCLE Cell Line Gene CNV Profiles	1.0	1.44683
GOPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7943
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68881
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29915
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24648
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
SNGM	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04946
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.307
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0338
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05961
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0189
BRD-K76252019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09519
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69737
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23207
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43695
PMC11968629-12672_2025_2184_MOESM1_ESM.pdf-5-AEBP1_AEBP1	Rummagene Transcription Factor Associations 2026	1.0	null
exhibits	GeneRIF Biological Term Annotations	1.0	null
SNU719	DepMap CRISPR Gene Dependency	1.0	2.37074
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45264
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4243
PMC9822887-41598_2022_27261_MOESM10_ESM.xlsx-HCT116_overlap_TCF7L2_CTNNB1_lo-Unnamed_1_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60865324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43414
BRD-K65182930_NVP-AUY922_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SAMSN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0073562
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IL17RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667262
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83615
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06738
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34994
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8077
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0466
NCIH1435	CCLE Cell Line Gene Expression Profiles	1.0	2.87264
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1373	CCLE Cell Line Gene CNV Profiles	1.0	1.7214
GTEX-TMMY-1926-SM-4DXUU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12671
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04973
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21806
HMC18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65661
ASH-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.857496
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59141
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59669
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
BRD-K48427969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21636
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06954
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10239
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
RASSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04097
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0632
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12903
ABHD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047997
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
proteolysis	GO Biological Process Annotations 2025	1.0	null
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63332
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10645
FBXL19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613627
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.03289
HHUA	DepMap CRISPR Gene Dependency	1.0	2.13926
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01328
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5397
CD46	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652066
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00736984
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67458
ZACN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00560956
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8168
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38222
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09248
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82963
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51162
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30627
NKX2-3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505757
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54706
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98763
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3776
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50286
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.08438
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4188
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1667
GSE195663_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21466
BRD-K98548675_Parthenolide_CL34_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
BRD-K66870022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19381
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04368
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29726
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23032
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.85986
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1527
SCHNEIDER-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
BRD-K53088255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34005
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5189
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841217
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53947
BRD-K20401833_N-{4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl}thiophene-2-sulfonamide_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
BRD-K86059888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01757
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.30678
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8557
BACH1	ChEA Transcription Factor Targets	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964345
BRD-K25447152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06094
METTL24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537798
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03506
Liver enzyme levels (alkaline phosphatase)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.0
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73436
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21174
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07256
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38589
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47012
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1349
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25319
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24356
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052321
LIVF001-012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28936
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31636
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0973
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37162
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55195
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0973
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51162
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85058
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933735
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.29498
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8223
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942763
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.841161
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86008
Mean Corpuscular Volume (Result)	DisGeNET Gene-Phenotype Associations	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13384
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AGXT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435351
NCI-H358 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5964
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A13082766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05801
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4B-Supplemental_Table_S4B_Differentially_expressed_genes_upon_ZFX_Knock_down_in_MCF-7_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-23a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31511
BRD-K06148621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05591
CRCGN014_HEPG2_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06592
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834213
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GTEX-WFJO-2026-SM-4LVM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34304
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90726
High Density Lipoprotein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4833
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00026
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29287
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07313
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43606
GJB7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0055639
BRD-K85865817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05656
SNU503	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07627
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38517
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49941
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.8167
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1969
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872491
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.067
CRCGN017_MCF10A.WT.HP_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2213
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16643
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60138
BRD-K75426080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27557
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8194
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825551
NDUFAF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605882
CCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594684
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29069
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45159
TFF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00783578
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
MX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00854375
nobox_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.151656
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84516
GPX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00883897
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46547
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66932
Peptidase S1A, HAT/DESC1	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K36164005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76904
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.181
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05876
BRD-K04284624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14627
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23597
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24443
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847457
BRD-K00366212_2-(2H-benzo[b][1,4]oxazin-4(3H)-yl)-N-benzyl-8-methoxyquinazolin-4-amine KUC106573N_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLCO2B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00597178
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11831
BRD-K28640166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01194
BRD-K75067815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06627
BRD-K42966513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27195
CA46	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851101
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10012
NTSR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415787
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
LAMTOR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564537
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25221
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00563
KCNS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512413
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21939
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03253
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26961
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33997
CEACAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644715
IDH3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00770128
PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
WSS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small	GeneRIF Biological Term Annotations	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952158
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949911
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964373
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
IKZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0040994
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54571
LRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525001
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85735
Melkersson-Rosenthal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.486
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25907
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32159948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09112
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7382
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34021
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Satellite fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.465
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
cephalothin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08289
DOCK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00845863
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0908
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6508
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57123
SOX9	ChEA Transcription Factor Targets	1.0	null
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3921
SNU81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85867
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061257
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41798
KCIMOH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65063
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.827
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963503
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56368
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
OC314	DepMap CRISPR Gene Dependency	1.0	3.38972
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7259
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04597
OVCAR-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43246
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14046
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865603
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29695
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853315
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4643
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64319
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16366
BRD-K23197669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04651
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1037
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0714
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18803
BRD-K13653700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2672
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71931
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00665
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43639
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14009
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63749
BTNL8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479897
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1615
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36107
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	1.46857
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81948
FERMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580027
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65611
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15235
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29929
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77235585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38191
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56298
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058029
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76695
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.73735
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85654
LDHAL6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494659
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58804
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29402
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8237
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3136
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_GSE63514_NOT_GSE7410_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10738
NCC010	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
DHH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518864
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64228
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952158
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31434
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30052
Fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.23164
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4298
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45979
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6315
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
protein metabolic process	GO Biological Process Annotations 2025	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.06708
BRD-K83567669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0909
KELLY	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38379
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20829
urokinasetype	GeneRIF Biological Term Annotations	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09767
HCC827	CCLE Cell Line Gene Expression Profiles	1.0	1.4114
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
salivary gland	HPA Tissue Gene Expression Profiles	1.0	0.941739
IKBIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00471208
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13401
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.70545
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03546
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68462
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34116
system process	GO Biological Process Annotations 2015	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62332
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53599
nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.765296
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KCNE4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682707
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.223
Posterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17735
CPNE7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523952
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48187
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2244
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26818
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6854
cavity	GeneRIF Biological Term Annotations	1.0	null
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72072
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27255
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07013
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08874
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84665
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
15833844-Table1S	GeneSigDB Published Gene Signatures	1.0	null
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74936
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.72237
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30387
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22254
Venom duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08405
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50283
BRD-K86986466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30275
PPARG	ChEA Transcription Factor Targets	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66644
NCI-H661	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
VERO C1008 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8994
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10007
BRD-K04798077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47428
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61192
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54896
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DU145	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63916
SIAH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502837
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07339
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60917
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHYH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559676
plasminogen	GeneRIF Biological Term Annotations	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05012
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859059
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33136
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24185
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53918
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05255
PMC12820306-41598_2025_32262_MOESM1_ESM.pdf-204-IRX2_IRX2	Rummagene Transcription Factor Associations 2026	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72746
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82563
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74267
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.294196
hsa-miR-4438	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36034
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
ZMAT3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.006658
Esophageal epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3858
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	2.165
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53867
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7822
BRD-K32648402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21141
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88823
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Salivary_Gland-ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.33582
KARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88446
trichostatin A-3791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85693
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05234
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82041
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52706
DUSP16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578271
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5733
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16747
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
TPM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606618
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
Gingival fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ARID4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50313
membrane part	GO Cellular Component Annotations 2015	1.0	null
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41588
BRD-K40175214_torin-1_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76112
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03052
LILRA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00656606
TRPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00505653
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
BRD-K16255400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24705
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47149
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70121
MCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00429872
BRD-K94516855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34314
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
P2RX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00524636
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39211770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15154
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19229
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10285
Perturb_11446_KD_TMEFF2_SRP302699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7376
BRD-K25734452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01156
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55921
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16815
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03201
CD47	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495264
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834497
SNU869	CCLE Cell Line Gene CNV Profiles	1.0	2.50489
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.08185
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.02031
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40961
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
FU97	DepMap CRISPR Gene Dependency	1.0	2.44883
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90139
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00341
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.90605
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.837931
ventral endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27175
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3489
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.34983
BRD-K63484613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11959
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.73101
serine hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-147b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
APCDD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616344
large	GeneRIF Biological Term Annotations	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25858
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38798
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45796
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0441
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35873
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.4113
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45438
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58847
CYP51A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464306
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75401
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3206
FOS	ENCODE Transcription Factor Targets	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
Trypsin-like cysteine/serine peptidase domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K91600270_NCGC00242557-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
P2RY2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00796423
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SSX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00818042
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTHFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557151
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
emerging	GeneRIF Biological Term Annotations	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498832
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45627
MERO83	DepMap CRISPR Gene Dependency	1.0	5.3353
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39068
A2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498752
FNIP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00629903
CRCGN008_HEPG2_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27015
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055485
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1889
hsa-miR-1178	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54409
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	2.42438
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7087
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.91945
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	1.91447
SKN-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40876
ESR1	ChEA Transcription Factor Targets	1.0	null
BRD-K35073835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02146
Total cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0204
HEXIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689378
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89832
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08384
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0815
GSE222829,GSE223009_0_v_1_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-28	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26524
Pallidum, ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10855
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4998
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.50872
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09859
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12864
hsa-miR-626	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914963
NMUR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586469
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93291
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83788
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44374
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26382
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6178
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36238
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64307
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
BRD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00875644
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37753
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1775
PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
HLMVEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05876
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846455
BTBD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533734
BRD-K18655724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41852
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-509-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65791
CNOT3	ChEA Transcription Factor Targets	1.0	null
JAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062712
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.26939
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37724
SALL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00426217
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47953
FNTA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0051529
GHRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664542
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5237
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.782784
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
ASIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487328
SERPINA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780324
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852983
HUPT4	DepMap CRISPR Gene Dependency	1.0	4.00007
NKX3-1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00653343
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9832
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7507
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06236
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3992
BRD-K75263760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76482
CHD1	ENCODE Transcription Factor Targets	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	6.32139
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97159
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0244
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06997
UBE2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58814
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41693
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
BRD-K69932463_AZD-8055_MCF10A_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849634
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1469
RAC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648943
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20759
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	3.98195
Middle East respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19511
DMS153	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5803
KCNJ4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523691
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68943
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64307
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3592
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3097
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9455
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51162
BRD-K85909950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08279
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09612
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35128
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MT-ATP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84965
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4368
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21915
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5432
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32673
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.42627
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34005
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.96
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08855
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27927
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08877
hsa-miR-518d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33868
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04766
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	2.81973
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0193
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49222
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tongue	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6759
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18508
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35399
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02196
CRCGN015_MCF10A.TP53.M_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01175
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tegmental field of p3 (Forel's field)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00566
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
Perturb_8779_Mut_SMARCB1_SRP223162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.15769
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56368
PMC7373278-pone.0236187.s013.xlsx-MCF7_genes_overexpressed_in_AR-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.893995
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45837
BRD-K60706752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04232
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.306
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3468
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40365
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17592
CBX7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643148
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4825
ATOH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26074
SHF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637277
BL1426 (FOXO1)	NURSA Protein Complexes	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50671
SEMA3E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632522
Bipolar Disorder_frontal cortex_GSE5388	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53686
BRD-K37140349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10537
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
CTRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646919
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.40769
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
NUCB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00720516
CNGA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00710331
GSPT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689019
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06735
GTEX-XUW1-0326-SM-4BOOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32635
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21047
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-586	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.00865
PMC12008806-mmc13.xlsx-ST12-Unnamed_37_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GJA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00686019
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961999
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10559
RNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93825
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64435
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.68851
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89923
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66872
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29435
GTEX-S3XE-1226-SM-4AD4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05109
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60826
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49858
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925041
hsa-miR-3167	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17588
FTC133	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57676
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.872395
GRHL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596376
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23301
RSRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20986
RBL1_KO_GDS1932_739_mouse_Neurospheres	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.924164
CCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594271
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.05313
KE39	DepMap CRISPR Gene Dependency	1.0	2.55837
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10401
Acute diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92916
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971563
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.00337
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7695
ICC2	DepMap CRISPR Gene Dependency	1.0	8.5636
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46178
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92048
pontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03506
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8846
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5716
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34867
proteolysis	GO Biological Process Annotations 2023	1.0	null
ZC3H12A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554795
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18842
Peptidase S1	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25575
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830858
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871905
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1546
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993205
BRD-K78939372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05968
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74121
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11341
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74806
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01988
GSE186633_1_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.31549
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9858
KMO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00704893
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14569
FABP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424206
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63569
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08122
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65449
PRUNE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764031
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12468
GTEX-S4Q7-0926-SM-4AD5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970851
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34581
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930701
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6694
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10305
NHEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
LDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
SYNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53168
GSE161170,GSE161268_0_v_2_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
viral	GeneRIF Biological Term Annotations	1.0	null
H2BC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08968
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23461
BRD-K67727634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10549
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25466
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.233
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515256
496100279_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.80396
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19405
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23747
BRD-K82249895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70681
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81403
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.878902
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0993
sublayer 6b of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37482
MDA-PCa-2b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44622
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8197
cognition	GO Biological Process Annotations 2023	1.0	null
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55817
BRD-K50841342_PAC 1_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ICC106	DepMap CRISPR Gene Dependency	1.0	2.11027
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.361
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03449
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930618
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
NMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052941
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30876
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SF268	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovarian follicular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949133
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64444
BRD-K50596260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21729
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
GSE173169,GSE173170_0_v_1_epc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25319
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14374
C1S	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00648301
BPIFA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00622461
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15861
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.67054
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88773
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20948
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0794
NCKAP1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00611631
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.72795
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05815
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00563
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70854
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933216
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.97888
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
CUX1	ChEA Transcription Factor Targets	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02799
YD15	DepMap CRISPR Gene Dependency	1.0	2.39495
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63868
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839807
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.845564
SLC12A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564484
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Secretory progenitor cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69795
ALPK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509366
GATA3	ENCODE Transcription Factor Targets	1.0	null
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
KP1N	DepMap CRISPR Gene Dependency	1.0	2.72988
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39086
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00781223
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93614
culture	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75305
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15804
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissue	GeneRIF Biological Term Annotations	1.0	null
NPPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00563069
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52778
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27271
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928513
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13201
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13274
BRD-K67868012_PI-103_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KCNK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640605
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38675
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.86644
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95349
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33062
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052769
PMC3251736__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7628
MTMR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0088207
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867805
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26668
ADPGK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589712
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63871
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990471
CRCGN017_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4787
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73432
SNAI2_01_225	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.27942
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14816
HK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00691859
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0442
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
EPHB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540421
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49904
L428	DepMap CRISPR Gene Dependency	1.0	2.01071
LANCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00604294
OE19	CCLE Cell Line Gene CNV Profiles	1.0	1.99149
OMC-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Peritoneal dialysis fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
KCTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93172
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9457
BRD-K44100512_KIN001-043_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15909
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03107
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29086
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90375
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08239
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230382
ADCY3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673344
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45469
BRD-K72615639_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19806
hsa-miR-489	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48057
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15071
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04127
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986744
MOLM-13	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
hsa-miR-526a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAMSAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00528129
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9024
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34886
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07449
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.201084
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4523
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8113
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07046
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7487
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062709
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0017
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10602
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18262
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61802
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
KS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95357
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5635
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31234
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00923
KRR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00804717
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82121
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.571745
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0444
ATF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511623
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42239
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59187
BRD-K96405393_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31577
cognition	GO Biological Process Annotations 2015	1.0	null
BRD-K24565713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20155
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52575
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91637
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918402
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937756
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21513
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849927
Perturb_10223_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K62177026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12583
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20358
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12273
CACNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00674205
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9849
GTEX-QDT8-2526-SM-48TYX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10707
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65535
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051999
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73342
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40459
serine	GeneRIF Biological Term Annotations	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77277
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62294
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56271
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851113
PMC5487013-pone.0179613.s002.xlsx-Cluster_1-GRHL3_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55067
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37575
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907841
BRD-K46311453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11409
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54703
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51162
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56337
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	0.931247
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49531
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2443
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
DNMT3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559187
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79741
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34623
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45079
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.273
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73711
Eb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898982
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9697
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17837
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32559
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49792
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849971
BRD-K64345025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17667
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K38720323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11608
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47833
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
NLRC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511005
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84727
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25302
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16233
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K01436366_XMD-1150_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23734
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18447
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869773
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02545
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2917
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3533
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04154
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05491
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63124
BRD-K94132559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33004
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833499
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1627
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47476
hsa-miR-505	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04812
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
chr4_68439599_T_G_b38	GTEx eQTL 2025	1.0	1.492
BRD-K07160568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07507
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02132
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18069
MAGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517976
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46293
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952158
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1781
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3608
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUP160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697655
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05959
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881387
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70507
RAB23	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611813
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29726
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51339
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19934
severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.825358
lung	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Esophageal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2675
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13698
EC-GI-10	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08884
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21806
Peptidase S1, trypsin family, active site	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20976
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12299
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39308
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55125
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63355
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30598
SAEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39517
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15644
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K88135858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07129
Human - Lung v1 - L2 - Ionocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34512
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060173
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857411
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35472
HET-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29314
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26234
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69444
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6856
Mean corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
PRPF4B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603535
EVSAT	DepMap CRISPR Gene Dependency	1.0	5.41683
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-876-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.76311
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.96513
BRD-K47962810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00942
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8603
occipito-temporal gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14511
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51745
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16743
BRD-K75904236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49131
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3496
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11719
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11979
HCC38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01988
BRD-K52620056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8556
BRD-K31805261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07773
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI H322M	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844601
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.94344
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908461
CHMP2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0105178
CAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620343
Urinary metabolite levels in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	9.23979
GTEX-QCQG-1226-SM-48U23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31622
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474258
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37934
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.31842
BRD-K36237864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35605
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7475
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49205
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.880903
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98672
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828268
PRKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692314
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46012
ITGA11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00531858
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.94
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36643
GSE160442,GSE160444_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.14978
hsa-miR-450b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898163
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
MDCK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46002
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987961
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.3897
SNU-407	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14605
XBP1_01_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.74236
ANXA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529721
PDE10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00564641
SF767	CCLE Cell Line Gene Expression Profiles	1.0	2.42812
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13284
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8315
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2874
CCL8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058844
PMC7793767-Table_2.docx-1-Downregulated_genes_in_the_pancreas_of_AA_vs_controls_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97207
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72468
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44489
BRD-K67868012_PI 103 hydrochloride_NCIH508_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2403
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFCP2L1_TFCP2L1	Rummagene Transcription Factor Associations 2026	1.0	null
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40708
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70707
BRD-K48764596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48272
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6489
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29086
LNCAPCLONEFGC	DepMap CRISPR Gene Dependency	1.0	2.06277
BRD-K59539129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1248
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.59734
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64086
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58345
Medication use (HMG CoA reductase inhibitors)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70321
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18272
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7302
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52977
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304142
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14171
HOXB13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519352
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13909
Perturb_15173_KO_PTPN14_SRP167101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.42238
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.615921
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847457
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99653
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.108
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5975
CDK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00348627
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19805
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27147
AGXT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456867
CYP2S1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00615997
GATA4_KO_GDS3486_483_mouse_jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5655
BRD-K95500387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29813
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96385
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07054
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15370_KD_TP53_SRP294453	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870256
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1908
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44284
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20951
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45258
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.35376
IM-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peptidase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824695
Perturb_8749_OE_TP53_SRP131095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27572
GZMK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511867
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847457
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28837
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
BRD-K67670670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34003
hsa-miR-23c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
serine-type peptidase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3724
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
REPS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597235
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.198
BRD-K54606188_(+)-JQ1_HA1E_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PTPRC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0082034
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3592
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55213
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14705
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13886
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65433
FHIP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46976
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.704227
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K13049116_BMS-754807_NCIH508_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57763
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919697
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70026
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.34017
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36579
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046053
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3136
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01579
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10649
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73601
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41852
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54954
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869773
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
STAMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492376
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29749
BRD-K89584002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05853
CRCGN016_MCF10A.WT.HP_24H:E05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44046
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71781
ITPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00670278
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0393
UACC893	DepMap CRISPR Gene Dependency	1.0	2.3406
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7483
BRD-K40174747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61757
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29699
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41442
Ionocyte cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
CAKI1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60071
APH1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536102
BRD-K16421840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89777
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10017
PTHrP_KD_GDS1664_438_human_MDA-MB-231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00588707
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75236
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
RHOV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519132
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.948778
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5118
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57967
desc1	GeneRIF Biological Term Annotations	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21206
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
SNU1033	CCLE Cell Line Gene CNV Profiles	1.0	1.45812
ATP9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486127
LSM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507712
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
ATL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35267
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01711
BRD-K97309399_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PC-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
Perturb_13730_KD_MMR_SRP193477	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.4291
SNU175	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45583
LZTS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060857
BRD-A17831693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19917
Omk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.715458
BRD-K98856654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54439
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92965
BRD-K94452277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51626
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1828
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5063
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00951
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.09467
Perturb_11363_KD_TMEFF2_SRP302699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1846
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6654
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953822
endopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
COLO-829	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
LMTK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565714
GTEX-OHPL-2526-SM-3MJGT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18554
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10738
BRD-K59019422_ED_CSC_15_NCIH508_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LI7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38389
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.89428
MED1_OE_GDS4846_11_human_LNCaP prostate cancer cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GPR157	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448264
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN008_HEPG2_24H:A11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0388
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52755
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40122
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885092
intermediate stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
URB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00756607
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
acronycine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82652
JHOS-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37085
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15147
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97312
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89282
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01876
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3075
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
CXCR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499537
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449947
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3486
host	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09748
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966875
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
SEMA7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607363
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68822
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961013
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.66798
KDM4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14217
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0095
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15666
SW1990	DepMap CRISPR Gene Dependency	1.0	2.75181
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
NCI-H1915	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05466
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885716
BHY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52625
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15084
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75535
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19125
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51217
proteinase	GeneRIF Biological Term Annotations	1.0	null
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CALM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00460262
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33178
ETK-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50124
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06822
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.77456
NLRC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489069
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
serine-type endopeptidase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27612
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
BRD-A80213327_NSC 23766_NCIH508_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6891
CCK81	DepMap CRISPR Gene Dependency	1.0	2.6044
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08885
KP2	CCLE Cell Line Gene Expression Profiles	1.0	1.84956
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955548
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97452
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896068
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65545
BRD-K55612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31782
CMK86	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11253
KMRC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96538
LS411N	DepMap CRISPR Gene Dependency	1.0	6.86216
BRD-K05886700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.40119
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51983
LGR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00736773
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6595
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9545
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58885
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34634
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054175
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1638
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63137
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7829
LSM6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540142
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5353
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952158
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950016
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	2.51524
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K19216856_(-)-Gallocatechin gallate_EFO27_6.0_h_88.8_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85204
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5943
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.724
TRIM35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29935
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13908
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92771
U138	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.16932
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14701
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BICR78	DepMap CRISPR Gene Dependency	1.0	5.01261
diagonal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23582
BRD-K48147099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39581
16353136-Table4	GeneSigDB Published Gene Signatures	1.0	null
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01688
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6054
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0213
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834154
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22616
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02799
activate	GeneRIF Biological Term Annotations	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1854
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15943
PMC7918644-LSA-2020-00974_TableS2.xlsx-5_SAd2_BD_D-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.97211
BRD-K39757396_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15417
BRD-K14914284_NCGC00187898-02_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FetalThyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06013
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57749
BRD-K33098168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45538
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827655
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40268
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38517
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01984
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37854
GLYAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427558
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1538
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01999
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.30108
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00824
NCIH2009	CCLE Cell Line Gene Expression Profiles	1.0	2.05399
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60148
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938359
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3773
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08171
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5944
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72808
ENOX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569395
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.855
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.491
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
dimethadione-5668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32327
GSE128634,GSE128636_1_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OPM-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58099
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53884
FGGY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516098
Cecal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAP1LC3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00705342
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47152
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6024
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07572
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1645
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02456
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.23475
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30352
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28761
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06862
D-263MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
BRD-K12502280_TG-101348_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92985
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865209
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17536
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36716
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068072
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2312
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.26568
LB771HNC	DepMap CRISPR Gene Dependency	1.0	4.70928
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5498
PDGFRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00765023
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35713
Banded collagen fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
ASCL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456037
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52011
BRD-K91654198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03331
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
BRD-K05286676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04066
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33195
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
F5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540985
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9055
2-PMDQ	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32267
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57297
BRD-K49108064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.173
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3782
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2337
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.25696
Lung microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	2.7733
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10576
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3136
HPAFII	DepMap CRISPR Gene Dependency	1.0	3.89218
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952158
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
neurological system process	GO Biological Process Annotations 2015	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1627
SETD1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00451611
BRD-K94288726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36981
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23582
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46024
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10855
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.876225
RDH8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00591279
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05386
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07585
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25406
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67227
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27678
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17544
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27175
LMX1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657012
PID1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.005185
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32092
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0282
RYR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511927
LUDLU1	CCLE Cell Line Gene Expression Profiles	1.0	1.35652
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91053
NRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00602124
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60059
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6446
HEC151	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86275
PDCD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524786
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880042
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61262
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.79684
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23800773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79844
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0151
BRD-K96898856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11584
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07829
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06333
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07395
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46451
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	13.2916
L3MBTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603009
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9102
scopolamine-4219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06207
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980926
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87794
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871055
ACTR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054575
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-79-ZZZ3_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4938
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	1.43362
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29486
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67784
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19875
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831407
NCIH322	CCLE Cell Line Gene Expression Profiles	1.0	1.62423
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06762
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07545
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	1.0	1.51883
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42176
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56046
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951196
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24349
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KIJK	DepMap CRISPR Gene Dependency	1.0	4.7998
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05511
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838086
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-380	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50386
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98606
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-23b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12268
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95315
95D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.396
peptidase activity, acting on l-amino acid peptides	GO Molecular Function Annotations 2015	1.0	null
BRD-K21662756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42529
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88968
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.43979
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70993
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56508
SNU685	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32093
ITGA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00871315
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69657
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83518
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.848
ITGA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00710579
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13747
BRD-K52075040_-666_HT115_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30257
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05985
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8318
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02857
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70634
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7407
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990575
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8684
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43722
GRIN2D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00431149
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35472
their	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4703-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70863
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895299
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64874
LTC4S	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00755839
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4588
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60237
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13197
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.827
BRD-K72966614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33759
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12399
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
hsa-miR-520c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964373
BRD-K77908580_entinostat_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
A2BAR_Deficiency_GDS3662_520_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r3 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08593
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0361
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24488
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0008
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19875
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8827
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
Pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20219
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2696
RPL22L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682026
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32763
SLC47A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614608
znf263_19887448_helas3_lof_human_gpl6884_gse19146	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.18825
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3592
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23932
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K30310320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11542
PMC12381255-41389_2025_576_MOESM2_ESM.xlsx-Progenitor_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25902
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35527
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K17705111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06288
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93948
U-266	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5183
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69749
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860712
MTNR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00578663
8505C	DepMap CRISPR Gene Dependency	1.0	5.0235
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35864
RTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00918331
CRCGN015_MCF10A_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08524
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.444676
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
LTB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565458
BRD-K45245001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23374
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62426
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92688
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54575
BRD-K34258763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25055
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929211
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.931827
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.951454
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44455
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48032
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36728
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
CARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004875
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86222
BRD-K98757606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31791
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.239
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31428
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20717
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22063
PMC4498179-srep11671-s1.pdf-131-IRF6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902495
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7797
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.782784
proteolysis	GO Biological Process Annotations 2015	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01174
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68897
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.36204
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1178
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
tamoxifen_homo sapiens_gpl3921_gse33366	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UGT1A9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522082
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3152
PRKAG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738909
PMC3251736__F2	PFOCR Pathway Figure Associations 2023	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40693
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825352
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953788
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TPST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583835
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9193
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13274
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45691
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13202
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63235
cellular	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80609
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0537
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60304
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.827
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
CHKA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00682979
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25676
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.698647
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23677
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94933
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19979
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41677
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36372
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35197
KDM6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00400773
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3597
BRD-K92379545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45324
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75089
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837324
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40169
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890462
Low Density Lipoprotein Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
SLC30A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00753159
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
Esophageal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Calu-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33358
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67426
HDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68702
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05555
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08309
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45102
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72858
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46069
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21349
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35722
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99653
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968953
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931763
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28361
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93525
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46567
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	182.133
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3123
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100516
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63247
CASP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484444
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47428
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35726
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8658
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17258
GJA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00411762
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7319
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07435
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91072
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5113
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.67
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4QS-0626-SM-3NMD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08268
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.844675
TWIST1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00706124
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0893
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.8
BRD-K76904668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1873
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
BRD-K16929626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23243
BRD-K13901498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78509
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82503
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_up-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97257
HEY	DepMap CRISPR Gene Dependency	1.0	2.44993
NELFA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00692403
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883904
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920876
CELA2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696202
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39625
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41302
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32626
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9821
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.065
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890311
single-organism process	GO Biological Process Annotations 2015	1.0	null
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15866
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SLC10A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623504
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57123
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947362
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08867
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37098
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20254
ISTMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45878
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
CHD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00649028
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46759
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17193
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K20987582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47541
BRD-K83475223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36239
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MEL270	DepMap CRISPR Gene Dependency	1.0	4.09038
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17159
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04229
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93613
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0514
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54822
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78809
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24097
PPP1R14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17225
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0465
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3427
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942003
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17505
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4727
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15333
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47687
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.45733
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51681
BRD-K23817660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73283
proteases	GeneRIF Biological Term Annotations	1.0	null
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03905
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66633
Lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
BRD-K86953192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1997
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19956
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18703
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00187
BRD-K64890080_BI-2536_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11374
ZNF646	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71735
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98125
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34719
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0534
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41091
HDAC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488959
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37342
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53353
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19507
GTEX-WFJO-0826-SM-4LVM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38225
BRD-K02458594_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9399
UBLC1	CCLE Cell Line Gene Expression Profiles	1.0	1.8204
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17772
clathrin-coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
ZNF692	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96087
Esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35832
BRD-K34604755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55571
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94197
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91399
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55239
BRD-K76892938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26383
HEATR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03234
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01764
pralidoxim	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62868
BRD-K57758244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06761
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
BCAP31	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557901
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24052
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46686
hsa-miR-4782-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04304
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35751
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03949
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839807
KYSE-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837232
BRD-K00337317_NU-7441_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51593
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33766
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63443
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	1.48556
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918992
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01031
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12086
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55936
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51617
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11113
BRD-K20807411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70631
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32558
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9542
BRD-K36168475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10256
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LOUCY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98184
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00093
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35057
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7108
viruses	GeneRIF Biological Term Annotations	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4803
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974924
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53126
ZGPAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612197
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889272
mspl	GeneRIF Biological Term Annotations	1.0	null
CUBN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00967523
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91803
trypsinlike	GeneRIF Biological Term Annotations	1.0	null
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18736
RUBCNL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00953272
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41302
IRGM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00770502
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.973847
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32073
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.05173
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-568	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60146
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41127
BRD-K31342827_GF-109203X_SNUC4_6.0_h_12.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30297
BRD-K24639784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15613
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18432
IRAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12919
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06132
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15216
MANSC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00678698
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0423
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9456
hsa-miR-4450	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN013_HEPG2_24H:B09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13589
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19989
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89789
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55195
thrombinlike	GeneRIF Biological Term Annotations	1.0	null
NCI-H82	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A55913614_Primaquine diphosphate_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64438
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08424
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22898
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29086
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871148
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60151
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64376
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29798
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60322
GLUD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062073
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250932
PTGER4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00947202
KNS-81-FD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40945
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08497
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LPAR5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582577
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12753
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6689_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.66967
ticlopidine-4074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K38046923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22945
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2441
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887907
s3s4	GeneRIF Biological Term Annotations	1.0	null
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.06091
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53836
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02484
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13747
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25512
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68431
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1065
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978252
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79048
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
Phycobilisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34578
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15957
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62442
NFYA_01_288	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.04924
ATAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474456
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11374
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1952
HCT116	DepMap CRISPR Gene Dependency	1.0	3.50914
BRD-K99338550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58484
TOR4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27911
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17355
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33598
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14325
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31129
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K98790311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02352
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FGF14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00694616
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
NAGPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763865
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49347
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13366
demonstrates	GeneRIF Biological Term Annotations	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4354
RCOR1	ChEA Transcription Factor Targets	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27053
METAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00413335
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05404
BRD-K01436366_XMD-1150_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.846118
TUBG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687002
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.867
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
accept	GeneRIF Biological Term Annotations	1.0	null
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871055
Severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54742
BRD-K64165176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33601
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25319
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96723
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04975
ACAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604879
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24228
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30406
BRD-K26872015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68707
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887806
hydrophobic	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.223
hsa-miR-519c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89068
Perturb_14557_OE_ZEB1_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.67547
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88463
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939836
ROS-50	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
OACP4C	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50327
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.70557
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23811
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043865
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31162
TE4	CCLE Cell Line Gene Expression Profiles	1.0	1.56082
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10855
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08049
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20625
mantle zone of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23582
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	2.07494
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36449
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13294
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.4699
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74823
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12726
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82795
Clathrin vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18559
GSE140651,GSE140653_3_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7882
Human - Lung v1 - L1 - Ionocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11267
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30947
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45589
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24856
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NME6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616726
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67787
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51331
BRD-K54595160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19838
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-FRA1_DN_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71538
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22465
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78319
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75598
LRRC8C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00954645
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50155
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76239
MCUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75065
L1CAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00698596
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.47
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06128
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32941
ZRANB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08218
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901189
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29382
TUBA4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00489667
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45818
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.746798
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65344
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63745
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07839
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59522
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17719
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56546
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46807
ARIH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457803
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5991
promote	GeneRIF Biological Term Annotations	1.0	null
EFM19	DepMap CRISPR Gene Dependency	1.0	2.9938
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1129
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58929
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19253
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	1.0	1.67474
serine-type peptidase activity	GO Molecular Function Annotations 2025	1.0	null
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34204
GSE145639_7_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.08438
C9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597101
CAL29	CCLE Cell Line Gene Expression Profiles	1.0	1.73619
MBD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00565768
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15957
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69023
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
BRD-K78288885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34731
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20835
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76918
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2804
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
CORL311	DepMap CRISPR Gene Dependency	1.0	2.1015
MM485	DepMap CRISPR Gene Dependency	1.0	6.83763
B3GAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561231
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31832
SKN	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848632
NALCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479202
LTB4R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516445
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24921
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29383
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7812
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56171
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4949
CFHR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00585931
GI1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3352
BRD-K97183783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17456
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27678
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05876
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976655
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309335
BRD-K26140483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02657
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2619
coronaviruses	GeneRIF Biological Term Annotations	1.0	null
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.26568
KCNH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00941932
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.841161
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S100A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538748
GALC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495221
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9862
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91697
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09907
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MHHCALL3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69794
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41343
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27381
Coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46302
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940091
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80707
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09047
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040473
Pulmonary microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.3301
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55195
RB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16563
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.86468
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35975
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90269
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.4321
CYCS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0102943
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51432
SLC13A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606476
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.909253
fold	GeneRIF Biological Term Annotations	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K79604175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3185
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09607
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841616
BCAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00819975
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3536
BRD-K49875070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5881
GSE202434,GSE202438_15_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01765
BRD-K29379469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42399
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46136
CRCGN008_HEPG2_24H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03165
CRCGN015_MCF10A_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06969
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.412
EHMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00441802
BRD-K11700411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56741
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881036
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059413
serine-type peptidase activity	GO Molecular Function Annotations 2015	1.0	null
influenza	GeneRIF Biological Term Annotations	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.09828
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
RFX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.103
NCIH3255	CCLE Cell Line Gene Expression Profiles	1.0	2.20926
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063928
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
GTEX-XUJ4-1626-SM-4BONV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74088
ERO1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00649398
PRKAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536328
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51945
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66131
BRD-K36209664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03521
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47269
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68549
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2559
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24856
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25557
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1944
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0394
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1606
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4897
GTEX-RWS6-1726-SM-47JXP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0899
hsa-miR-519b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.558
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59441
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16973
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22345
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63827
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4858
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.548
ARHGDIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65534
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23349
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35311
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08063
BRD-K50387473_XMD-892_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16827
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32737
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57418
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
Checkpoint clamp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13266
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72854
THY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702885
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.96828
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0656
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904269
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963786
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4087
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.36
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50522
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05888
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14314
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.434
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0475
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.827
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1246
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.73057
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55783
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57751
Perturb_8688_KD_FAT1_SRP358313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.13419
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25738
BRD-K89122173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35788
GSE178714_5_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27489
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
CRCGN016_MCF10A.WT.HP_24H:D21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29148
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42195
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41988
RHOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00404199
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.026
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08198
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052071
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.108
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05961
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5796
rhombomere 8	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01718
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89997
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67363
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11374
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997178
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75401
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78622
Apolipoprotein B levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.0
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0321
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39584
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39374
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.30369
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9287
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05764
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29915
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNNC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00677036
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32771
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10388
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31234
SEC14L4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00498748
ADH1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587462
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29301
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31124
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64341
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30136
NCIH1869	CCLE Cell Line Gene Expression Profiles	1.0	1.87904
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11374
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06477
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.13311
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	1.55182
DETROIT562	DepMap CRISPR Gene Dependency	1.0	3.11336
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.53759
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
Perturb_12529_KD_STAT3_SRP081918	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4572
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13542
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8554
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34259
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20657
CMK	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829639
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.54709
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31987
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41202
C1orf210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45569
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Peptidase S1A, chymotrypsin-type	InterPro Predicted Protein Domain Annotations	1.0	null
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24073
LRRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614741
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5613
PCK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065102
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
BRD-K69466030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1641
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47356
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial derivative	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.70939
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06625
BRD-K68546494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45301
GJA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508309
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22591
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77853
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981377
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41202
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
Perturb_15480_OE_ERG_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.2241
BRD-K88568253_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1796
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35122
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44366
BRD-K02646507_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MBD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421114
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23359
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
hsa-miR-1273e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60148
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
hsa-miR-2054	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SUCLG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673943
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94211
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58562
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57798
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13614
IGR-37	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.46155
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20362
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1627
BRD-K18620798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38592
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87324885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48653
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.841161
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69878
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39426
BRD-K08817808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89618
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-142-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00094
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16802067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32509
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29868
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3156
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8459
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34418
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.4774
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83001
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.265494
cSARS Bat SRBD_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.28091
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55853
SCLY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578508
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.12771
SHMAC5	DepMap CRISPR Gene Dependency	1.0	4.17558
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4143
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6404
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0537
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89838
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-1.08438
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.06097
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6287
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059715
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50362
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5325
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62868
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49962
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36967
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92667
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09076
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.095
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18725
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952156
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75336
BRD-K83426111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10776
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898163
residues	GeneRIF Biological Term Annotations	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883722
BRD-K90382497_GW-843682X_HEPG2_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-1244	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Tonsil	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CAV3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00579578
SEC14L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738953
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null