association	dataset	threshold value	standardized value
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14302
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9146
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6749
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384265
PEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40112
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475652
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5845
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47397
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1236
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285865
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17777
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269927
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04621
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42233
Diamine N-acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.312
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735521
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4491
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3827
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WD-62-UB45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483781
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04264
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01711
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85183
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	218.705
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04343
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7211
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0145
IE-38-FB31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218705
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58018
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.725
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OVCA-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3604
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10445
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436155
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46508
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4558
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.7347
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07868
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5597
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30723
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241092
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3241
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44304
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19928
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3963
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90213
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39262
GSE140965_2_v_3_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07263
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.077
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74204
GLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0555
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67499
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48148
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31055
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270785
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0312
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3396
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225417
NCI-H322 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
CRCGN011_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2041
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.9895
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249966
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16089
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22695
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51661
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8349
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.517
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-00-EK89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349815
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60371
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.239
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22518
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.795
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72185
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77462
CRCGN015_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01541
positive regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08002
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432845
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28718
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34611
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44356
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6113
CRCGN015_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00686
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60425
actin monomer binding	GO Molecular Function Annotations 2025	1.0	null
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08706
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60469
NKX3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65747
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23313
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.181
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56314
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28364
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23107
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00972
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34365
regulation of cell motility	GO Biological Process Annotations 2025	1.0	null
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304472
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208663
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10482
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09164
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32255
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22644
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6394
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2436
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69174
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55035
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44605
Internode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2235
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23989
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314581
DE-37-JV37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300125
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.1364
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84302
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45551
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.182
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7619
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53441
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52165
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317534
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31989
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207186
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06141
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8719
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67526
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR-75-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27807
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03018
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.884861
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1823
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.527
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.6524
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4643
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56813
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263407
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357003
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3867
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249126
jvm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34715
UA-39-TN76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223618
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399819
QA-50-YO37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244155
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61471
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22255
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
XD-71-WI50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204561
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72183
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88291
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05921
CRCGN011_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75755
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08187
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0918
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20214
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43248
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.439
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0413
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2646
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.95414
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1405
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63275
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.089
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.244
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2009
HA-30-KD77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271898
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19484
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22838
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8337
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285356
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48388
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526708
interleukin-3 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.645943
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.11
HB-06-WU12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214273
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81141
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94291
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40425
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30056
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266848
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38594
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92702
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2597
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0945
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13255
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02457
AB-71-CI37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200054
ZBTB7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89482
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66838
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE204811,GSE204813_1_v_3_trim29_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272385
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203735
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65375
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45717
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240143
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8772
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4602
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38267
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06122
XC-88-ZM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276427
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.807
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49819
CXCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3662
YA-85-VH07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200776
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10862
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5154
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95254
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71168
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16912
GTPBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1727
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_4_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_11_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300009
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8966
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47043
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285692
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80593
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69029
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3109
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22978
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394398
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5832
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4035
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7061
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39851
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52868
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04705
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.20785
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4189
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48923
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678361
regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1902
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.61235
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36834
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1176
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02821
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.095
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.00689
CRCGN008_HEPG2_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3356
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02711
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9142
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.566755
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80747
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53877
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46562
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.3853
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9729
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306359
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22699
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306824
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6919
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5044
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50398
AC-44-UR36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343799
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1641
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13021
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03293
GD-46-OD81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242492
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205016
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09531
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.081
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2917
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.165
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7912
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	162.239
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2033
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27262
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.088
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.744177
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11888
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436697
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30003
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04807
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.74191
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25153
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0717
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00162
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9887
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24763
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85486
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208679
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16319
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94687
NCAPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33995
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66929
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296584
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11466
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5416
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90723
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01883
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5745
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5835
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254641
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31166
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15389
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of cell motility	GO Biological Process Annotations 2025	1.0	null
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221645
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9958
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0084
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0877
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1272
GSE202434,GSE202438_3_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318425
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4369
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401492
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7038
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16973
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48172
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301012
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72808
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60719
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02115
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400048
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478212
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36815
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4484
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476083
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13383
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208564
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
actin binding	GO Molecular Function Annotations 2025	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38753
Alevin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
BC-26-LE04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247495
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3233
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31498
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.02695
B4GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03412
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01359
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.35445
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40302
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1176
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1051
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327978
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2811
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00331
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461635
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6653
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227457
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20175
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225679
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8082
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39564
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13044
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58193
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8669
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06434
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407729
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6021
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23035
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43986
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04776
WF-85-JN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267675
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27389
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05509
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44125
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49302
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09755
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6202
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.2759
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286344
DES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26508
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.0529
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3259
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77599
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1852
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580968
LIPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06515
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74869
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20288
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.883
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1057
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58459
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71436
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.485
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13998
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08863
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8394
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7302
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.794
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66922
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209625
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949101
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5817
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.582
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4444
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68155
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15662
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42341
UF-14-LK87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282385
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55642
p3h3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32364
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.251
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34781
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6906
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6678
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62064
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1266
PC-80-LV29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360575
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16963
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581127
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.2206
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383892
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43701
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71096
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388528
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8745
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32991
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27208
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0461
ZNF641	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36374
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6137
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.104
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.629333
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29399
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02685
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	256.814
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.623
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53843
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.46927
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59484
SNX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31117
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64336
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36859
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5437
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1596
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16834
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4794
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27391
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0966
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26394
Blood plasma	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11492
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.35698
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03931
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IF-08-GY16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334298
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04006
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1635
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.27975
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.502
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.2314
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.133
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65414
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29178
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05065
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214478
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09538
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.208
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20376
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06317
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22808
CRCGN015_MCF10A.WT.HP_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13047
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3726
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74829
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98661
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.629023
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1597
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13156
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91031
GSC cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09483
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4659
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.016
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205337
ST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50014
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34075
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02959
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44927
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6071
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29688
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268326
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.6121
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.83467
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46678
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5711
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4205
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09819
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6532
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7622
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406795
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7641
lb4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251824
CRCGN016_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15152
C3orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14982
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.2511
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379961
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0908
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307108
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271712
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4709
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00262
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26815
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8079
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51912
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2948
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84325
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7856
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38685
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45342
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64147
PPP1R15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39962
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214467
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8394
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7888
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15227
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48075
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70037
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4647
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27763
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2739
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18499
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.42205
CE-03-YQ91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352669
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58873
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17388
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26582
GSE120612_4_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0376
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03169
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8758
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0989
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467577
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4385
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.554
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.6908
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6267
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	182.389
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54529
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5827
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35932
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3862
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17435
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26355
CRCGN015_MCF10A_48H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02464
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311633
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0813
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60137
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COX6B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23339
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25321
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919406
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64495
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7634
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47033
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.0213
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14636
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80527
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.4662
CRCGN016_MCF10A.WT.HP_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0972
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54776
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47371
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48956
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43829
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343503
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78349
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77059
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16946
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08523
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.31805
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69177
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66883
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5557
Occipital pole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386192
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36798
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30605
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214698
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3238
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.949994
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360607
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00798
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69291
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7623
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.478
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07092
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400193
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FB-32-PY27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211334
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42233
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07696
lb24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9466
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316593
Blood platelet	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464489
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240228
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466786
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32366
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.8136
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0315
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30081
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7066
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31347
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2039
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45164
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	264.962
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.3411
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22458
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32087
TMEM129	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82161
Nuclear RNA export factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.195
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.773
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6354
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409073
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220651
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CaSki cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244015
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83227
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415797
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94872
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.978
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427266
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0824
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51474
FAM117B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.458
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366765
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82927
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44776
GSE160442,GSE160444_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30902
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64223
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3607
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84018
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.965
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3119
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53796
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2132
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0992
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	213.043
ED-71-GA72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296579
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	305.57
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.111
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0652
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245602
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.48621
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4313
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3642
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	320.0
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55046
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2373
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41889
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18105
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437478
CRCGN013_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08865
COPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59555
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5048
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59245
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.312
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03801
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.597
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221951
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.307
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4112
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5753
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4444
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.2845
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3741
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20005
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.888
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42549
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55985
EF-80-OD07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245263
HGC-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24475
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98925
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216312
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3862
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232213
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7678
RWPE-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8664
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211041
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6984
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47296
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8971
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
CRCGN015_MCF10A_48H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04905
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36683
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23606
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.832695
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43446
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07373
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426011
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.0879
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8465
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204117
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5233
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.2416
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.387
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49422
OE-84-HO42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.294806
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254979
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331842
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7345
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7721
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286083
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82676
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15643
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6831
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
GD-69-KC91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347553
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1962
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3559
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1444
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206151
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5207
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38665
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85185
CRCGN012_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1921
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310847
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82199
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30109
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.806166
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52745
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0944
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3127
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70313
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9008
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8575
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270269
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47429
S0-EE-Y79N_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236346
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44006
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72286
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15237
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4801
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19862
DC-43-KF54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249698
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.62
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45105
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80978
CRCGN015_MCF10A.WT.HP_24H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06792
CRCGN011_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79705
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214768
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.105
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0539
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25367
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
PMC9691391-7945884.f3.pdf-89-ENSG00000175727_MLXIP	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1395
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37004
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651496
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52652
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3101
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42285
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12685
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8818
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621868
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1774
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82669
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33267
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69768
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24901
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39784
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65213
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.811
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38517
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17191
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677481
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484256
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07187
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4546
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2441
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.924
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84769
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5514
CRCGN015_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23451
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58828
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19063
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.58675
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16663
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339254
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28584
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9961
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17962
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242053
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76218
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66196
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.60529
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null