association	dataset	threshold value	standardized value
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57959
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65606
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
meglumine-6445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
kidney inflammation	MPO Gene-Phenotype Associations	1.0	null
H2373	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4155
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54757
BRD-K36104357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76916
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05443
clorgiline-5005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2069
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13859
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80951
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057513
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77308
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829121
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5905
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A46317335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34259
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29208
ZZZ3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05659
BL-41	GDSC Cell Line Gene Expression Profiles	1.0	1.89061
12433680-Table2	GeneSigDB Published Gene Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330824
K562_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019467
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
localized	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_9_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5851
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	GDSC Cell Line Gene Expression Profiles	1.0	1.56302
efficient	GeneRIF Biological Term Annotations	1.0	null
PR8(H1N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.07563
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36284
GSE135030_11_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16194
Sarcoplasmic reticulum lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42236
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35037
Attention function in attention deficit hyperactive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23857
fluocinonide-3414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.60649
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42893
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
DNA polymerase III, clamp loader complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.67
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.8824
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	2.30771
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
condensed chromosome	GO Cellular Component Annotations 2015	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.871435
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.47656
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43004
Polysomal ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05988
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59922784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88655
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QD-57-GT11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299652
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867935
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91526
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07075
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.21248
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956626
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.89875
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.12833
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9303
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21219
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04395
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10176
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.09259
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41251
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4828
Schizophrenia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25066
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63227
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47692
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857884
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221655
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09777
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6001
BRD-K77498991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35718
CBX3	ENCODE Transcription Factor Targets	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00251
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18181
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.640426
BRD-K43680691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18922
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	2.48187
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93162
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.524
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.990734
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835617
abnormal pancreas physiology	MPO Gene-Phenotype Associations	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.51644
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.69231
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.60849
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46445
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19725
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.069932
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.267
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74212
K562_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162861
3504_GPN3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.592213
enlarged spleen	MGI Mouse Phenotype Associations 2023	1.0	null
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390466
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02519
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.3246
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
abnormal digestive system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04142
leflunomide-6102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_Curcumin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187552
PMC10806738-mmc2.xlsx-Table_S2-Table_S2_Table_of_significantly_adjusted_p-valued_0_05_down-regulated_genes_log2FC_-1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19725
NANOG_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.601889
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02771
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58215
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dna conformation change	GO Biological Process Annotations 2015	1.0	null
Patent ductus arteriosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-K10157835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11133
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39511
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5637	CCLE Cell Line Gene Expression Profiles	1.0	1.50504
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45083
Necrosis	CTD Gene-Disease Associations	1.0	1.7544
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32018176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54707
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78824
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24213
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36659
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96794
BRD-K91615044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53906
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58205
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92176
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01715
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35207
BRD-K31720099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0273
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13298
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23949
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057184
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26253
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.988
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064077
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.564582
HOP62	DepMap CRISPR Gene Dependency	1.0	3.43673
gallamine triethiodide-2221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	2.15472
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08085
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907706
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28659
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.04924
DNA conformation change	GO Biological Process Annotations 2023	1.0	null
iii	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56561
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.25372
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17378
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2113
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34007
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02975
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18758
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52876244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29252
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02793
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	1.35284
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.04914
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931499
SNU46	CCLE Cell Line Gene CNV Profiles	1.0	1.53196
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1031
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ofloxacin-2302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zomepirac-4479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-3	GDSC Cell Line Gene Expression Profiles	1.0	1.55151
K562_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158846
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4177
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3972
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.70342
BRD-K62659610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43669
BL1074 (AURKB)	NURSA Protein Complexes	1.0	null
BRD-K45222498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21888
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41599
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028235
CAOV3	CCLE Cell Line Gene Expression Profiles	1.0	2.55459
pa317	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76379
CB-38-AW77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324664
BRD-K36764343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32938
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88315
ETS1	ChEA Transcription Factor Targets	1.0	null
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88583132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05827
Nuclear speckles	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8581
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11152
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07833
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870035
BRD-A73559168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0531
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.837581
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5258
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28287
BRD-K58932103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52221
WM1552C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K03554945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06185
ethoxyquin-3421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Salivarygland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.840384
BRD-K82130737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51584
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29269
K562_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145559
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247923
K562_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157703
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.98357
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3733_KO_Trp53_SRP296860	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.56936
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72843176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69742
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09634
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15941
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52159
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36489
BRD-K17482709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23262
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915132
BRD-K04883778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2455
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31363
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19881
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4211
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.596168
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5764
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54222
TP53	ChEA Transcription Factor Targets	1.0	null
K562_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162182
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47922
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227749
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2843
BRD-K19755525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05232
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07708
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79688948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00903
VM-CUB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL3007 (RMI1)	NURSA Protein Complexes	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0615
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.878
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.4005
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717221
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A46950333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92706
GATA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K09693670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00437
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13592
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55751
decamethonium bromide-7353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14897
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57236
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910531
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03544
JUND	ENCODE Transcription Factor Targets	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clemizole-3672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BL3390 (E2F1)	NURSA Protein Complexes	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.47661
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20202
GSE157262,GSE157268_3_v_0_ythdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5268
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930217
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842756
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosome	GO Cellular Component Annotations 2015	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841221
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40357
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.67842
5658_NFYC_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.657768
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93333
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.683249
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64706
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73314
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AARSD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K16047442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52795
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18095
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852962
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.96002
BRD-K82662168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18794
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441531
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55029
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14212
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11405
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCCPAN2_PANCREAS	CCLE Cell Line Proteomics	1.0	12.9784
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.46949
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45094
congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.458241
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
sulfadiazine-5523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1462
BRD-K82314391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3739
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18225
abnormal lymph organ size	MPO Gene-Phenotype Associations	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8331_SPC24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.597781
CBX2	ENCODE Transcription Factor Targets	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04967
wehi274.1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G3-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.884909
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924319
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976539
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VDR	ChEA Transcription Factor Targets	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.9563
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.82143
ZNF274_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908792
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01577
6291_PHF5A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.551816
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93789
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36925
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49623
BRD-A70099008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03314
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01082
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33748
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.582469
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69495
reduced female fertility	MPO Gene-Phenotype Associations	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.1974
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41498
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10427
BRD-K72549552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07482
amidopyrine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02445
K562_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213302
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09011
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25275
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07398
abnormal immune system morphology	MPO Gene-Phenotype Associations	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30808
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8899
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13861
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23484
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22702
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23369
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18523
Omega speckle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860506
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
7559_RRN3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.514636
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66054
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	3.07836
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868697
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88519
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.115
BL480 (UBE3A)	NURSA Protein Complexes	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848756
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62308
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06119
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17252
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
SARS-BatSRBD_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.87134
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977399
BRD-K19009595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02294
BRD-K67390084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5623
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926256
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18755
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54901
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82719
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
8621_SYMPK_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.527074
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12825
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.858476
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7031-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826721
9178_TOP3B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.696713
naftifine-2974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10854
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881464
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1437	DepMap CRISPR Gene Dependency	1.0	3.06858
BRD-K53221607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09219
RXRA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25484053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7364
Nucleolar ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899065
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5053
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3974
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40871
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U-266	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.08137
RXRA	ENCODE Transcription Factor Targets	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65741
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92592
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal inflammatory response	MPO Gene-Phenotype Associations	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02402
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.818222
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	3.19995
FOSL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976524
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.51976
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930217
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
dna topoisomerase type i activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978009
topoisomerase	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74998
BRD-K01329192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31358
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02825
K562	DepMap CRISPR Gene Dependency	1.0	7.06837
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71074
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58654
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88887
PISD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86754
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923909
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49954
BRD-K13844473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31303
Chromosome 15q13.3 microdeletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3737
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07921
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07758
BRD-K84241565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50794
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.82355
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17537
z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.31088
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01422
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosomes	GeneRIF Biological Term Annotations	1.0	null
BRD-K79995507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.424
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5178
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11167
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24887
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2487
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RECQL5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161161
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transcription export complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0927
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14068
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16084
SHI1	DepMap CRISPR Gene Dependency	1.0	2.0908
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219684
ZFPM1	Pathway Commons Protein-Protein Interactions	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850362
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50498
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
5699_NKX6-1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.822668
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30874
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13625
saquinavir-3549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8123
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06556
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.11219
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58794
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14132
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61869
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63026
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29377
BRD-K97393725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63273
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
lateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09437
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
IHF-DNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09597
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32967
abnormal lymph node morphology	MPO Gene-Phenotype Associations	1.0	null
PMC11887674-MOL2-19-808-s003.xlsx-TCF4_interactors_in_Kelly-Unnamed_0_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09468
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963637
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050862
KP3	DepMap CRISPR Gene Dependency	1.0	2.58599
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.23011
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2396
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.94506
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ7-mel	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60513
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16079
BRD-K43714461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01371
harmol-7320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44145
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838984
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06489
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33755
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.97002
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7741
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02417
BRD-K35176035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03977
KDM5A	ENCODE Transcription Factor Targets	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34889
BRD-K68162101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20596
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90213
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21365
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIVF001-018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01705
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07816
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6542_POLR2C_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.706316
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469186
PMC11239565-uxae032_suppl_supplementary_data_s1.pdf-25-ZNF513_ZNF513	Rummagene Transcription Factor Associations 2026	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6581
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22705
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33454
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10988
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58102
Transcription export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.448
BRD-K17895004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37198
ARID3A	ENCODE Transcription Factor Targets	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22093
TCF3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75983763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72649
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11224
abnormal kidney cortex morphology	MPO Gene-Phenotype Associations	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.44132
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33542
6-bromoindirubin-3'-oxime-7048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23784
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64726
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.15852
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.07553
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157147
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88611
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
EP300	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HD-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36855
SP4	ENCODE Transcription Factor Targets	1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04961
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.30936
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.233183
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8604
OVK-18	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.83982
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13123
BRD-K64531863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54936
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140312
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dna topoisomerase activity	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.664
BRD-K69791255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84355
BRD-K04695993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7458
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17818
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995895
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65231
BRD-K36961619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19728
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02908
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46106
8218_SNRNP27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.988165
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4384
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.836847
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277278
isomerase activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_821_OE_Rspo1_SRP325709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.63416
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heliotrine-6035	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19808871-TableS3	GeneSigDB Published Gene Signatures	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27361
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280326
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12242
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8825
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
penbutolol-7476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01667
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03257
NB6	DepMap CRISPR Gene Dependency	1.0	2.49097
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2759 (MED17)	NURSA Protein Complexes	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38822
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02644
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45732260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86991
FOXA2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89333198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60851
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
IST-MES1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.08391
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03257
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.95022
CAKI1_KIDNEY	CCLE Cell Line Proteomics	1.0	2.01943
MAZ	ENCODE Transcription Factor Targets	1.0	null
EXOC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00444
BRD-K87595216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26103
BRD-K99078335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0265
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	2.08294
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30955
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.84051
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01289
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.4849
BRD-K33200274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00705
GOS3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32164
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13283
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997512
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37953
ciclacillin-4536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.36079
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39768
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83654
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dermatitis	MGI Mouse Phenotype Associations 2023	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955876
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44897
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562	CCLE Cell Line Gene CNV Profiles	1.0	2.24806
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
HCC1419	GDSC Cell Line Gene Expression Profiles	-1.0	-2.21243
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70422
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294223
CEBPB_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
abnormal renal corpuscle morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06678
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.27479
SRF	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1767
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1516
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321387
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15694916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68281
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77964
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mre11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938718
abnormal spleen morphology	MPO Gene-Phenotype Associations	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293457
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.907988
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-A64523751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50056
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.75678
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72050226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0954
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal nephron morphology	MPO Gene-Phenotype Associations	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31134
phensuximide-3521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11798
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45316
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17505
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9098426-41540_2022_225_MOESM4_ESM.xls-HCT116_NR1D1_KO-Gene_NR1D1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875543
K562_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199494
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954342
canrenoic acid-6783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85002
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38645
stomach inflammation	MGI Mouse Phenotype Associations 2023	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35526
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal female reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL8995 (CASC3)	NURSA Protein Complexes	1.0	null
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.58076
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921831
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27035
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19866
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-k562_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51681402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66804
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91944
enlarged spleen	MPO Gene-Phenotype Associations	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73001
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06913
cyproterone-4470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05223209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10774
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86553
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GE-44-AZ94_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220177
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27051
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97736
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855863
EKVX	CCLE Cell Line Gene CNV Profiles	1.0	1.52069
BRD-K13697445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45519
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02099
ramipril-6792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chromosome segregation	GO Biological Process Annotations 2015	1.0	null
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59788
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5739
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.911542
BRD-K11518913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29116
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
2122_DDX46_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.733659
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60956
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39057
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04698
cefoperazone-5424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81395
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649528
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02829
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930217
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-84-BQ58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207291
BRD-K28982281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74436
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27744
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170169
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908932
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
isoform	GeneRIF Biological Term Annotations	1.0	null
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42893
BRD-K28354175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15221
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69603
NFIC	ENCODE Transcription Factor Targets	1.0	null
ZZZ3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945688
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.084694
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73021
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23231
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37238
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kinetoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.885643
BRD-K43918582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05088
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835246
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885394
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13601
Brain Lower Grade Glioma_LGG_TCGA-R8-A6YH-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4152_KO_Chd8_SRP165973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13005
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10247
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
COLO679	CCLE Cell Line Gene CNV Profiles	1.0	2.31248
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83224
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522601
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18163
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00463
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59261663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08631
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56196
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896785
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.71926
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91098
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30835
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926642
mefloquine-6205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0241
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.347113
SF172	CCLE Cell Line Gene CNV Profiles	1.0	1.83168
LB996-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98592
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-586	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.786327
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09637
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07043
SUZ12	ENCODE Transcription Factor Targets	1.0	null
heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.698313
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843921
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49144
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4571
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K65910757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22042
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
increased inflammatory response	MGI Mouse Phenotype Associations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TD-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.96266
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
RNA polymerase II, holoenzyme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.66
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5088
TAF1	ENCODE Transcription Factor Targets	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843749
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884009
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977399
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22322
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77514
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.55124
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36933
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53409
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.700554
7648_SAP18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604714
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32687
BL2094 (MSH2)	NURSA Protein Complexes	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
corl47	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.02841
HCC70	DepMap CRISPR Gene Dependency	1.0	2.5813
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38879
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28816
abnormal lung morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7423_RPAP2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.558234
BRD-A26583774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15399
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
aneuploidy	MPO Gene-Phenotype Associations	1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44982
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28136
BRD-K16154498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01984
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20386565-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28148
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BD-15-VR68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257858
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8815
BRD-K71040831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60222
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189692
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79663
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X4-01A-51R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88984
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213706
SNU182	DepMap CRISPR Gene Dependency	1.0	4.57147
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hela	GeneRIF Biological Term Annotations	1.0	null
BRD-K14216093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1023
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994917
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35675
FLI1	ChEA Transcription Factor Targets	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31927
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03825
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.3621
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.536489
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K99522349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1159
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11726
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14623
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904236
hematopoietic system phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K63024248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00118
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985329
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49748
etynodiol-5024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.088377
single-stranded DNA-binding protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.676948
BRD-K84815485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47658
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42461
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16989
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44237
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878425
ELK4	ENCODE Transcription Factor Targets	1.0	null
5005_METTL4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.501934
verteporfin-6817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
IGR1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66615
thiostrepton-4385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00292
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51371
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898577
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443018
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.946268
ELF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10835
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-ATF2_UP_V1_DN-Ensemble_gene_ID_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
increased inflammatory response	MPO Gene-Phenotype Associations	1.0	null
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
SUDHL10	DepMap CRISPR Gene Dependency	1.0	2.65205
CAL12T	CCLE Cell Line Gene Expression Profiles	1.0	2.01061
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956288
anaphase	GeneRIF Biological Term Annotations	1.0	null
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018801
oxybenzone-5410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0036
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47715
PMC4510000-supp_gr.179044.114_Supplemental_Tables.xlsx-ST12-Unnamed_5_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21040167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1568
pyrithyldione-3482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
DNA conformation change	GO Biological Process Annotations 2025	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	3.26361
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941021
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496874
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00709
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.38876
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
k562	HPA Cell Line Gene Expression Profiles	1.0	2.71748
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58221
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.068994
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
1269_CCDC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.80274
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protects	GeneRIF Biological Term Annotations	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87803080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45727
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11974
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.71067
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.96567
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51876
AD-86-ES28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262271
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.13804
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A78T-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13226
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1067
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45458
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494953
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44725
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.81906
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.081617
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71561
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0575
EW22	DepMap CRISPR Gene Dependency	1.0	2.55438
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947786
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11198
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226513
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29533
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900885
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994101
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62205
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921716
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058362
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945909
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15285842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00884
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07195
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862607
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6505
PMC9602726__F5	PFOCR Pathway Figure Associations 2024	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00218
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
clotrimazole-3166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857737
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225573
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57739
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39158
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hexylcaine-5768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17204
BRD-K51328581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03407
6550_POLR2I_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508125
TP53-32428506-HUMAN-LIVER-HEPTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26847
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236467
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A772-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0979
MAFK	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5793
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08331
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06995
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57135
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72811
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48172
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34977
K562_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153903
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43923
BRD-K72807299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68297
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058706
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985246
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
reduced female fertility	MGI Mouse Phenotype Associations 2023	1.0	null
DNA topoisomerase activity	GO Molecular Function Annotations 2025	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87812655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05868
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0446
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21354
Amyotrophic lateral sclerosis type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
A4FUK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91382
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BTK_knockout_2_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.699068
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42974
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00761
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03355
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06138
A498	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.893706
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06659
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61821542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2724
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977663
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02641
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15389388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2725
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85239
proxymetacaine-6492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24863
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02296
NANOG	ChEA Transcription Factor Targets	1.0	null
K562_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225272
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12481
Learning Disorders	CTD Gene-Disease Associations	1.0	1.04757
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27031
Polysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203775
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenacetin-4111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07825
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81152
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59427
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21036
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3448
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43798
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K79697020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37064
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	3.20759
nuclear part	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951635
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508722
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.115294
RPMI8226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9767
Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.8164
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872627
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929474
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915029
BRD-K86986621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03948
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12255
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35966
MYBL2	ChEA Transcription Factor Targets	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.1356
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35598
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892021
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13007
NCIH1755	DepMap CRISPR Gene Dependency	1.0	3.63044
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K59535072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89566
BRD-K52797126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30389
BTK_mutant_1_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.354084
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999083
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.26364
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02462
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36729
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261837
20081105-ST-1	GeneSigDB Published Gene Signatures	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8174725-ppat.1009603.s006.xlsx-neg_nsp3-ZSGvs_Untr-nsp3-ZSG_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18394
mitotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.961607
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.9474
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ND-07-WN37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211902
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
KYSE-520	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40437
BRD-K61795707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4488
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29475
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
18172295-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05933
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05928
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09976
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44688
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60913
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.05319
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77297
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tetralogy of fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.890078
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16406
abnormal immune system organ morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02411
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2723
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967743
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74653
EF-80-OD07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202464
10478_ZNF585A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525446
abnormal skin physiology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19764912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61624
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_01_18	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59094
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883183
Edema	CTD Gene-Disease Associations	1.0	1.04757
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39328339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23634
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28532
HCC1359	DepMap CRISPR Gene Dependency	1.0	4.04202
ELK1	ENCODE Transcription Factor Targets	1.0	null
BRD-K39715006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05441
4149_INTS4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.865067
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conjunctival folliculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477752
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05606
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09438
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13565
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12411
Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10295
MMS19	Pathway Commons Protein-Protein Interactions	1.0	null
dermatitis	MPO Gene-Phenotype Associations	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17616
tribenoside-3507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cognitive disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923055
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30945
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07285
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968456
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40165
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980156
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38467
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58347
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97814
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4331
BRD-K64640769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00902
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39657
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16931
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47815
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61314
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86381
BRD-K87023633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4823
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87012
EGR1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3237
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.8088
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
early reproductive senescence	MGI Mouse Phenotype Associations 2023	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89701103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3734
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12077
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09899
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33132
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.270423
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906284
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.79331
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32547
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52963
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15574
single-organism process	GO Biological Process Annotations 2015	1.0	null
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29003
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49296
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15985
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91165
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49449
BRD-K40733000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00782
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968532
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02007
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.042613
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76729384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.091
TCF7	ChEA Transcription Factor Targets	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875733
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03711
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53306
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE208226,GSE208227_2_v_1_ell3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55448
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91372
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6085
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eye Abnormalities	CTD Gene-Disease Associations	1.0	1.21663
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.87025
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31699
RNA topoisomerase activity	GO Molecular Function Annotations 2025	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.554937
BRD-A36428246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42983
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2293
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Neurological pain disorder_Dorsal Root Ganglia_GSE15041	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.38862
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975037
isotretinoin_homo sapiens_gpl8300_gds3215	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
PMC2768459-6605275x5.xls-Hoja1-Supplementary_Table_S2_Differentially_expressed_genes_within_the_ESR1-negative_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-2_E2F1-Gene_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75529374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44195
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16919185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01053
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907925
parahippocampal gyrus, right, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854576
Encysting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894324
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22308901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02266
damage	GeneRIF Biological Term Annotations	1.0	null
BRD-K77316284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11668
4153_INTS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.577612
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.827
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.49607
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chlorcyclizine-4546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914164
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28101
BRD-K75330923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.16491
Rto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159302
BRD-K33128056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34644
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.49551
bretylium tosilate-6674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13542
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
K562_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130371
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06408
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2548
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046294
BRD-K96164740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58146
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31001
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63999
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8356
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08936
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08509
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.9552
BRD-K59272984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10842
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
premature death	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97418
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thioperamide-3392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35278
TRIM24_knockout_298_GDS3087	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.08179
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.5576
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49627
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21257
K562_XAV-939_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018453
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30749
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52973
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gibberellic acid-7330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15918
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13028
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824343
LS411N_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.49954
DNA topoisomerase type I (single strand cut, ATP-independent) activity	GO Molecular Function Annotations 2025	1.0	null
levonorgestrel-3406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65734
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.59212
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05971
GATA4	ChEA Transcription Factor Targets	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	DepMap CRISPR Gene Dependency	1.0	5.73202
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24576
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35071
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.994
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6281
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826642
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13335
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.212
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42465630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71703
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40461
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2646
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35969
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17696
TEAD4_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2398 (DDB2)	NURSA Protein Complexes	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09373
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938903
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32712
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.951929
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior colliculus, external nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77246
NR3C1	ENCODE Transcription Factor Targets	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13192
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2055
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057213
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13925
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24554824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30432
K562_Alvespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016964
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
K562_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185546
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2811
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924454
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5911
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40138
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.985369
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23201
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1999
BRD-K62000282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78625
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.86785
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.04291
3572_GTF2F2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.69801
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17385
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22394
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360117
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39199
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
melatonin-6293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7728
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69922285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23023
Intestinal disaccharidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1242
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70798
BRD-K08199068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26107
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.32935
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF408	Pathway Commons Protein-Protein Interactions	1.0	null
VCAP_PROSTATE	CCLE Cell Line Proteomics	1.0	5.16
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31081052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32662
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.611995
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.82314
DNA damage response	GO Biological Process Annotations 2025	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900523
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
CUX1	ENCODE Transcription Factor Targets	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38692
BRD-K03935681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04033
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166589
w chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.37907
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97268
abnormal litter size	MPO Gene-Phenotype Associations	1.0	null
Androgen insensitivity syndrome_Fibroblast_GSE3871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.80479
BRD-K78088874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10572
8661_TAF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.667393
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23618
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929474
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324635
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69987
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97368902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50773
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36353
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834135
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.979665
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.812
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02644
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
etomidate-3519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.34341
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24227
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.270423
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25848
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05046
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12577
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947926
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900321
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53487
GATA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11892
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13525
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
Prestwick-675-7381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MacAB-TolC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
BRD-K54742099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73231
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredPeptides-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37042
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12394622-41698_2025_1096_MOESM1_ESM.docx-0-SOX2_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20440082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17327
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K42855618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0293
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42804
apramycin-7334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Micronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10108
BRD-K56783915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6056
phenelzine-4360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0603
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228403
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16562
ACC3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01182
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22683888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02692
MECOM	ChEA Transcription Factor Targets	1.0	null
MPF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BL5118 (PAK1)	NURSA Protein Complexes	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12325
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14103
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07963
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach inflammation	MPO Gene-Phenotype Associations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
BRD-A94740628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04364
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
BRD-K12531686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01019
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03597
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.462772
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049962
organelle	GO Cellular Component Annotations 2015	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.13878
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971109
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.988947
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24216
AE-02-OC25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208458
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.839015
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87481
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08317
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19608
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85668
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924249
A3KAW	DepMap CRISPR Gene Dependency	1.0	3.22745
BRD-K34695725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10858
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043811
5548_NDUFAF5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.527291
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01137
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86805
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31967
BRD-K78681155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14264
SREBF1	ENCODE Transcription Factor Targets	1.0	null
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32383
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dna metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05352
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12304
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856657
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62178
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06141
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29792
CRCGN008_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73545
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
naftidrofuryl-5287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40538
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33239
2633_EN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.551968
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03999
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906415
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986726
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238813
early reproductive senescence	MPO Gene-Phenotype Associations	1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362994
MIB1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98617
NRF1	ENCODE Transcription Factor Targets	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	0.851917
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
LCAM1	DepMap CRISPR Gene Dependency	1.0	2.21884
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02396
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244129
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal endocrine pancreas morphology	MPO Gene-Phenotype Associations	1.0	null
Ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.6
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.980472
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22557
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79871
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854674
TBX5	ChEA Transcription Factor Targets	1.0	null
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
K562_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152701
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10886
RNF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15964
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
8662_TAF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.505488
POU2F2	ENCODE Transcription Factor Targets	1.0	null
BRD-K02671211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1859
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.049
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5271
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23756
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-2.31023
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835617
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993601
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19148
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bergenin-7224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84678
NR4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6118
SMN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73654
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284534
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52634
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824372
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46697
skimmianine-5766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.35268
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40685792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.404
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20191
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14545
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20723
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20733942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04126
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01381
BRD-K34721572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07342
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026202
TRIM28_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16914
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827624
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rixosome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09581
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10584
Cerebrooculofacioskeletal syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82521339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54271
BRD-K59542165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37477
TIS granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72
BRD-K94014790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02117
abnormal meiosis	MPO Gene-Phenotype Associations	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950867
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chromosome 22q11.2 microduplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.903256
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24711
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9581
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052166
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
survival	GeneRIF Biological Term Annotations	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49743
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.41246
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34193
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.640087
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.43883
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24566
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hydroxyzine-5006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87982677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28728
PMC3226433-1756-8935-4-20-S1.XLS-Table_S5_Miz-1_KD_gene_exp_chan-Genes_up-regulated_in_Miz-1_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057073
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	1.47428
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24452
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83571
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01295
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.464742
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264404
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12881
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03717
NCIH1693	CCLE Cell Line Gene CNV Profiles	-1.0	-2.53223
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1275
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25701
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
3502_GPN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.536927
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17505
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12366
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tetralogy of Fallot	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208912
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88315
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02979
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43820045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6879
Atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25109
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52747
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
16207250-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0321
PAX5	ENCODE Transcription Factor Targets	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50936
DNA topoisomerase, type IA, domain 2	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29149
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.80686
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31797
BV-173	GDSC Cell Line Gene Expression Profiles	1.0	1.53084
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7456
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.224492
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55858
Velocardiofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75626008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12786
DNA topoisomerase, type IA, core domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.629
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84033
MDAMB157_BREAST	CCLE Cell Line Proteomics	1.0	2.42399
SNU620	DepMap CRISPR Gene Dependency	1.0	4.90578
SETDB1	ENCODE Transcription Factor Targets	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.35345
BRD-K44061011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84037
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54449
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07595
4939_MED17_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.630751
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99574
HPBALL	CCLE Cell Line Gene Expression Profiles	1.0	1.44209
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965981
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217352
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73101
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lidoflazine-6278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36476
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88518
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24068
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cefmetazole-7222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37615
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57077
OE33_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.34552
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) (MMHCC)_GSE1025	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.4156
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5072
nitrendipine-5405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930217
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal respiratory system morphology	MPO Gene-Phenotype Associations	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48608
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27429
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52535
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35215
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865668
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21521
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.5781
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.225557
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857138
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51515
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01081
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60911
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39369
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950901
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enalapril-7026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
levetiracetam_rattus norvegicus_gpl1355_brainstem_gds1864	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09286
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23312
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0741
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827473
Homologous recombination	KEGG Pathways 2026	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924454
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.2013
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20965
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.092
poly(a) rna binding	GO Molecular Function Annotations 2015	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8486
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30471
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.68497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5432-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92344227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44949
MYBL2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-633	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K03995743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12596
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34067
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04043
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.17629
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06786
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00727
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16987
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95485
JQ007 (MSH6)	NURSA Protein Complexes	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03195
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058553
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889822
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46577
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	3.0229
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01006
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13469
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31117
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69273
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894736
DNA topoisomerase, type IA, central region, subdomain 2	InterPro Predicted Protein Domain Annotations	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955834
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.83336
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56868
BRD-K02833343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04616
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02749
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT	CCLE Cell Line Gene Expression Profiles	1.0	1.58905
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06042
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47732
cortical renal glomerulopathies	MPO Gene-Phenotype Associations	1.0	null
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912957
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14262397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12087
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92736
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07307589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03761
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10333
PMC11321995-41556_2024_1460_MOESM2_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Unique_genes_with_exons_significantly_correlated_with_OTX2_expression_in_Group_3_and_Group_4_MB_tumors_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Toprim domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K41700289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54511
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3376
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56018
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.09646
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.549
BL697 (CC2D1A)	NURSA Protein Complexes	1.0	null
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_10262_KO_Esrrg_SRP119935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.413
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS633T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23378
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30629
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal cell morphology	MPO Gene-Phenotype Associations	1.0	null
TAL1_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54867
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0567
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826425
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33912
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2192
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25276
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32169
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCNA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.64523
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
BRD-K89515752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36414
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5302
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859603
1929_CTDP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.559723
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8718
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890955
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857886
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34001
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410949
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.04733
DNA topoisomerase, type IA	InterPro Predicted Protein Domain Annotations	1.0	null
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34004
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13877
Spinocerebellar ataxia with axonal neuropathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852035
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91944
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.3811
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858379
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gastric	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.861559
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04675
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48344
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51646
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21062
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507681
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10584
PATU8988T_PANCREAS	CCLE Cell Line Proteomics	1.0	3.10753
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6923
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IE-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05047
BRD-K76114475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06793
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.4102
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.1631
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03257
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840651
abnormal kidney physiology	MPO Gene-Phenotype Associations	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.1
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.267267
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
12941840-Table1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10072
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Gene Expression Profiles	1.0	1.33181
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24255
BRD-K06392309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46593
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56058
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16358
PMC11947124-41419_2025_7562_MOESM1_ESM.docx-119-ZNF84_ZNF84	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G8-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12787
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45297
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90926
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00041
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153219
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965464
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	2.08659
CEBPB	ENCODE Transcription Factor Targets	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBLN5	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23218
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.47158
nordihydroguaiaretic acid-524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873889
abnormal male meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10221
Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2245
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17651
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
BRD-K63504496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3354
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03166
ChIP_SMAD1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74824
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54456
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248763
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09105
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00178
ZEB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868989
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827218
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354328
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.50988
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50133
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
region	GeneRIF Biological Term Annotations	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF__SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930052
DNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87643
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805813
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.34711
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.09307
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870681
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92917
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.99175
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60172
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
RPMI-8226	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56526
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6897
Weight Loss	CTD Gene-Disease Associations	1.0	1.51835
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41047
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34142
transcription	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185977
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836104
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9207
copper sulfate-500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59436
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-dORF6_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.15708
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25158
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Fragile X Syndrome	DisGeNET Gene-Disease Associations	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61666
hydrastine hydrochloride-6011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905539
BRD-K32205799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25545
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32412
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64567
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983415
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59309
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.065267
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K66416915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39912
PDK1_knockout_80_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.09472
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00459
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228709
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dna topological change	GO Biological Process Annotations 2015	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00607
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23409
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8766
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64592
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5979
BRD-K96417480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50465
HS751T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30115
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05494
NGP	DepMap CRISPR Gene Dependency	1.0	2.21582
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Endodeoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.48
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831541
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33496
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4577
beta	GeneRIF Biological Term Annotations	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.366929
Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSG	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2128
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.617679
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
carbinoxamine-6786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
647-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2113
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86676
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSS131R	DepMap CRISPR Gene Dependency	1.0	3.4793
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976524
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97470305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64853
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84038
BRD-K57502201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17246
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39727
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34110797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00546
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716463
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33015
ATF3	ENCODE Transcription Factor Targets	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52292
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03257
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58606
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear splicing speckle	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57003
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
memantine-4017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29784863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27302
K562_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156586
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24471810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71866
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.14965
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325301
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A89237309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30615
HT55	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52117
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.41436
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8369
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14255
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80102
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8245
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52778
PSMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08351
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.6507
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41536
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU46	CCLE Cell Line Gene Expression Profiles	1.0	2.02241
RAD21	ENCODE Transcription Factor Targets	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.52036
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3281
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16673
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K32906083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31587
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7712
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13523
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K79748783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24766
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.439
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39889
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02564
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05998
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56103
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1597
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64245731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72268
BRD-K76351135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45046
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51925
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.925369
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863706
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25836
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11566
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66298
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FAM96B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33594
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34044
C-75-6399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40081
abnormal cell nucleus morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867639
GSE159937_2_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76263570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42626
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0251
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40255
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906382
EP300_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06233
BRD-K85908443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36755
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825214
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
SMAD1	ChEA Transcription Factor Targets	1.0	null
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45704
ERBB2_knockdown_231_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.39437
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88826
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7681
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal pancreas morphology	MPO Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89981
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04952
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxolamine-4969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K85951787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44811
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40745
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830663
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27051
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2519
TK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59432
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
PPARD	ChEA Transcription Factor Targets	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112995,GSE132079_1_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7173_RBM39_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.528985
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5129
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06188
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14256
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904961
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
4217_ISY1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.728401
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thrombocytopenia-absent radius syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
NURF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
CENPF	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043051
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DiaA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
haloperidol-1144	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338775
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pilus tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9941
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.21919
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63_01_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59476
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50467
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UPF2	Pathway Commons Protein-Protein Interactions	1.0	null
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942786
fragile x syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.642221
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08469
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_5_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03711
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39362
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916049
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48258
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2429 (NCOA4)	NURSA Protein Complexes	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53249
skin inflammation	MPO Gene-Phenotype Associations	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953679
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19221
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
propranolol-5358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1733
A498	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79737
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126794
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15281
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GF-35-IT27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235996
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22093
MCAS	CCLE Cell Line Gene Expression Profiles	1.0	1.49584
KRTAP4-12	Pathway Commons Protein-Protein Interactions	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298905
TAL1	ChEA Transcription Factor Targets	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12412
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95213130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22336
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.81274
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14179
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8343
SMN-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02925
Autism	DisGeNET Gene-Disease Associations	1.0	null
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
TAF7	ENCODE Transcription Factor Targets	1.0	null
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47269
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57077
SNU81	DepMap CRISPR Gene Dependency	1.0	2.79235
BRD-K86638309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7164
trimethobenzamide-4100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pempidine-3832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35858
TAL1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933148
NMB	DepMap CRISPR Gene Dependency	1.0	2.62671
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943253
HNF4A	ChEA Transcription Factor Targets	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.68861
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormal renal glomerulus morphology	MPO Gene-Phenotype Associations	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NP5	DepMap CRISPR Gene Dependency	1.0	2.7665
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0357
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57501
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66905
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amiodarone-3296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09842
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.914108
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
SNRPB	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13715_KO_ASXL3_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.82141
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.583615
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826089
7527_RPS5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.62476
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04137
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18224
KDM4A	ENCODE Transcription Factor Targets	1.0	null
BRD-K14417813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65309
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CP-320650-01-4560	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KA-37-GD83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374593
Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas inflammation	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K63493628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08009
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
pancreatic islet hyperplasia	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22312
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1942
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.04488
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OD-96-OP94_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2561
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15462
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20327
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07943
BRD-K43535770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27021
Inflammation	CTD Gene-Disease Associations	1.0	1.15089
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73479560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90192
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0656
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.894
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73739802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17037
CTV1DM	DepMap CRISPR Gene Dependency	1.0	4.75953
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56815
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.19045
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70189
HEC59	DepMap CRISPR Gene Dependency	1.0	2.47258
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68303333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13324
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13768
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.57178
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903484
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43044
core	GeneRIF Biological Term Annotations	1.0	null
Cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11176
pancreas inflammation	MPO Gene-Phenotype Associations	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76350099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69441
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47071
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K14795621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68194
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38645
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulatory	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999443
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13137
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92807
Perturb_10127_Mut_MYB_SRP080924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97933
LS	DepMap CRISPR Gene Dependency	1.0	2.37658
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02284
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47285
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75103
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.018
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58588
skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.493354
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10162
KMH2	CCLE Cell Line Gene CNV Profiles	1.0	1.7102
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10168_KO_TOP2A_SRP297586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.64195
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617739
SP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K24719325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07164
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04921
SRF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7970325__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isocorydine-2780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus	GeneRIF Biological Term Annotations	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88315
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4787
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15861
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942038
BRD-K45713337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67656
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55603
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dna binding	GO Molecular Function Annotations 2015	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881177
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE188721_3_v_1_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.15647
glomerulonephritis	MPO Gene-Phenotype Associations	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8888
GSE215351,GSE215794_7_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79183
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1313
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842322
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05924
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987421
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2943-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31584
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01423
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03251
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
premature aging	MPO Gene-Phenotype Associations	1.0	null
BRD-K04044480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06169
BRD-K61439686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58686
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254217
P4E6	DepMap CRISPR Gene Dependency	1.0	2.16295
BRD-K77403813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37082
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.79803
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991126
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K85917058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51549
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31898
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899006
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.916226
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-1126-SM-3P613	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03369
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.83574
BL6398 (BCAR3)	NURSA Protein Complexes	1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57587
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6548_POLR2G_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.06069
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14455
BRD-K75679095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06065
BRD-K12397820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01659
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925082
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833434
BRD-K24977393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05724
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33469
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4602270__F6	PFOCR Pathway Figure Associations 2023	1.0	null
assessing	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4664
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062558
IRF4	ENCODE Transcription Factor Targets	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.027
BRD-K56149020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10308
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32712
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.02671
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13146924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20505
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleic acid conformation isomerase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946042
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261398
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03792
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.093
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878233
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46586
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00605
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01258
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931928
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.43844
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	1.0	1.38881
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01432
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16256
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41604824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50565
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158635
element	GeneRIF Biological Term Annotations	1.0	null
BRD-K00797068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29849
BRD-K51054674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11561
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36154
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA replication preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
beta-escin-4544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03937
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27774
chromosome organization	GO Biological Process Annotations 2015	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23792
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091427
NOS1	DepMap CRISPR Gene Dependency	1.0	2.69919
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3832
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900207
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01856
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0395
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41748
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30531
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25982
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09215
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99574
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.537794
Bloom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07738
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.69154
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.18242
ASH2L	ChEA Transcription Factor Targets	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.6626
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039565
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65139
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32131
cinchonine-2789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
carisoprodol-4955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-2426-SM-3MJHL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90534
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21525
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947436
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11501
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64982
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85564
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19786
carteolol-3276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36875
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326067
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
DNA topoisomerase III-beta-TDRD3 complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16072
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218188
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PMC6930440-jcav11p0520s3.xlsx-CG_vs_MI-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216141
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32093
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
exon-exon junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15009
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24976
BRD-K42671829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04574
CREB1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
BRD-K47467075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45115
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17573
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
BRD-K20199304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09216
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04891
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01147
Atrophy	CTD Gene-Disease Associations	1.0	1.38213
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46299
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13364
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30046
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.2664
2235_DKC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.578382
nucleus	GO Cellular Component Annotations 2025	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23434
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51614
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19184
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16189
FOS	ENCODE Transcription Factor Targets	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17954
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303386
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57639176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50868
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHT-101	GDSC Cell Line Gene Expression Profiles	-1.0	-2.34878
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.61055
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
miconazole-6615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945793
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5806898-pbio.2004411.s003.xlsx-MR_plot_data-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
JVE127	DepMap CRISPR Gene Dependency	1.0	2.25296
PMC4602270__F6	PFOCR Pathway Figure Associations 2024	1.0	null
PMC7782698-41467_2020_20367_MOESM9_ESM.xlsx-Student_s_t-test_BP1_ILK_GFP-Gene_names_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BL5061 (POLH)	NURSA Protein Complexes	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9837_WDR70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.568597
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.327
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
BL5166 (CDKN2A)	NURSA Protein Complexes	1.0	null
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979083
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10458
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.560816
K562_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184726
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22167
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39253
palmatine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46672
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01634
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94877
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900467
BRD-K76628294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42228
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938959
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.52987
MDA-MB-415	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LIVF001-013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97172
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28247
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03856
BRD-K71758378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34693
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844092
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49379
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03825
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-1.32482
BRD-K53752646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56372
4945_MED22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.515893
nes	HPA Cell Line Gene Expression Profiles	1.0	1.02228
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Dowregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862921
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.988448
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	2.32468
PRC2_EDD_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18446
BRD-K16093370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18125
Kidney rhabdoid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
NCI-H292	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58049
K562_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175706
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suramin sodium-7529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
almotriptan	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56713
BRD-K40565784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19838
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34867
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27491
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42098
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326453
EW-13	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69537
Ctf18 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0115
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23606
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73459389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19665
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.42012
BRD-K97562463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38934
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IST-MES1	GDSC Cell Line Gene Expression Profiles	-1.0	-3.11569
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57115
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887311
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.370944
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.622967
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cyclizine-2880	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16695519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2358
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21971
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88692
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle organization	GO Biological Process Annotations 2015	1.0	null
KARPAS299	DepMap CRISPR Gene Dependency	1.0	3.03158
pentoxifylline-2127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34033
abnormal chromosome number	MPO Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200006
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7632
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
prognosis	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18286
GSE198165,GSE198166_8_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNA repair	GO Biological Process Annotations 2025	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56302
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3336_GEMIN5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.651894
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02822
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89174
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03903
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511969
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19387
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96721
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01109
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04761
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194548
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enlarged submandibular lymph nodes	MPO Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01191
D542MG	DepMap CRISPR Gene Dependency	1.0	2.7253
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26084
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1214
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.261
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47062
BRD-K21579116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3251
isoforms	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10635891-mmc2.docx-1-ZNF318_ZNF318	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55618
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO775	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35786
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969319
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.996069
ES4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
8793_TCP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.603801
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212753
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08753
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98435
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29088
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94291
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95465
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898495
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBC801 ()	NURSA Protein Complexes	1.0	null
benzathine benzylpenicillin-4140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
6542_POLR2C_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.75518
PMC6451636-NIHMS79910-supplement-Supplementary_table_1.xlsx-MAF_1_not_in_control_exomes-Gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2882
K562_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015814
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	2.5915
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9078
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90108753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76057
BRD-K67572910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12553
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10135449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00592
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02502
NCI-H524	GDSC Cell Line Gene Expression Profiles	1.0	1.74701
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79092
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27085
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.776909
NCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.47169
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05559
Chromosome 22q11.2 deletion syndrome, distal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
nfe2l2_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.203468
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184625
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.98122
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888798
BRD-K56057104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98147
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.98062
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00427
BRD-K87939000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24863
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78928
BRD-K74056311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53079
USF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31474
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.539908
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09437
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
metacycline-2901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26431
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13574
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28938
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0706
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
TAF15-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41717398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32563
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19906
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1143	CCLE Cell Line Gene Expression Profiles	1.0	1.38868
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EW-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27484
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18125
5732_NOL10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.508985
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97225
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869315
PC3	DepMap CRISPR Gene Dependency	1.0	6.22965
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67715154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26785
Submandibular lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12966
SMAD4	ChEA Transcription Factor Targets	1.0	null
BRD-K18888894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13686
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01557
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3403
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.87861
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Renal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03733
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30159
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00686
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cinchophen	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23825
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5689
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05969
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.53483
SPI1	ENCODE Transcription Factor Targets	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.07447
renal/urinary system inflammation	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9258
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.833
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875733
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890213
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07663
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.21248
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70261
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Translation repressor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
thiamazole-4550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70564
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76155
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.11675
cobalt chloride-379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88069191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24631
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02133
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55831
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53111
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX2_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96974
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46625
pivmecillinam-7312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21257
translocations	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74365
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
cytoplasm	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27012
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.26265
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13874
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08996
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Huh-7.5.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
MEF2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57186
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00007
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07429
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835617
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38159
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052051
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80472
LC1SQSF	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48718
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60877
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48414
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00768
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17385
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26392
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
prilocaine-2352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8322
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	3.67269
2795_EXOSC8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506019
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A59683007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26128
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78841
BL6687 (ASH1L)	NURSA Protein Complexes	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06498
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6392
KDM5B	ChEA Transcription Factor Targets	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.03506
Messenger ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30553
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal submandibular lymph node morphology	MPO Gene-Phenotype Associations	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23525
Li-Fraumeni syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
BRD-K60483981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95011
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96854
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14638
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31857
6-benzylaminopurine-3726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K26402831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34338
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07677
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851207
RPMI-7951	GDSC Cell Line Gene Expression Profiles	-1.0	-2.4746
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
11906190-Table2a-1	GeneSigDB Published Gene Signatures	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10013
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70096
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNA packaging complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18998
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934297
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13898
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982432
abnormal gland physiology	MPO Gene-Phenotype Associations	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7398
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81197
nifenazone-2285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
DNA topological change	GO Biological Process Annotations 2025	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48826
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83919
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19002
K562_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167156
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6247
FOSL1	ENCODE Transcription Factor Targets	1.0	null
DNA topoisomerase, type IA, central region, subdomain 1	InterPro Predicted Protein Domain Annotations	1.0	null
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07997
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA_high-signal_selected_bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.259
BRD-K71644199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37439
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22194
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858506
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33538
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063158
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03125
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39362
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64977
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2922
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942109
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06113
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34177
Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78813
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
7833_SF3A2_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502025
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08065
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4126
STAT1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862895
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867273
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360534
CBC2142 (ESCO1)	NURSA Protein Complexes	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83016
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00794
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74534
brompheniramine-3271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00041
binding	GO Molecular Function Annotations 2015	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0801
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041391
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10328
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913079
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964766
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.94641
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49273
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.137097
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
PMC7817097-abb9149_Table_S2.xlsx-293T-TET2-FLAG-Table_S2_Mass_spectrometry_results_for_endogenous_SMCHD1-FLAG_in_ES_cells_and_TET2-FLAG_in_293T_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
Palatine uvula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48414
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13876
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3215
MKN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5542
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
rna binding	GO Molecular Function Annotations 2015	1.0	null
SREBF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870486
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960074
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTF2B	ENCODE Transcription Factor Targets	1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.3613
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975335
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pheneticillin-6105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
glomerulonephritis	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K14756138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08896
Holliday junction resolvase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.283
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.347
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52833964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0281
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05487
BRD-K77697725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51916
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.01025
EKVX	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.54163
azathioprine-5262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
6541_POLR2B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.573969
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
chromosomal	GeneRIF Biological Term Annotations	1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422734
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61579
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.236819
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63082
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65457
riluzole-4689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
frequency	GeneRIF Biological Term Annotations	1.0	null
breast	GeneRIF Biological Term Annotations	1.0	null
Generalized seizures_Brain_GSE6614	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.58732
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840201
SNU-182	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
15744745-Table2b	GeneSigDB Published Gene Signatures	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56045
BRD-K76664579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19729
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17442
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190434
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.53527
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.601
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
6537_POLR1D_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525209
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05251
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58519
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29771129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43917
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53086
GSE217378_1_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640854
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65632
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936063
abnormal salivary gland morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_5152_KD_Ell3_SRP013333	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.11849
mephentermine-4707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23371
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860859
BRD-K63864310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12243
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877927
abnormal pancreatic islet size	MPO Gene-Phenotype Associations	1.0	null
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81831
metacetamol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03842
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HES1_01_266	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.6241
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00691
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71193
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.955923
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04745
18786252-TableS1	GeneSigDB Published Gene Signatures	1.0	null
enlarged pancreatic islets	MPO Gene-Phenotype Associations	1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17102
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378008
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-ChIP_and_HES4_UP_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15202679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38791
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isthmic part of mesencephalic trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00695
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69753
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02259
CHD1	ENCODE Transcription Factor Targets	1.0	null
useful	GeneRIF Biological Term Annotations	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.53619
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874969
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26983
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.26825
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased litter size	MGI Mouse Phenotype Associations 2023	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.07996
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3834
DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249742
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3347
artery disease	GWASdb SNP-Disease Associations	1.0	0.098077
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5806
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96034
etilefrine-7350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1703
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.888414
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07974
memantine-4135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29441
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10055234-media-3.xlsx-ZCCHC17_KD_DSGs_637-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNA binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12145
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977399
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal digestive system physiology	MPO Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.41122
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07706
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0006
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aneuploidy	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72488
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06049
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11112
SUM1315MO2	DepMap CRISPR Gene Dependency	1.0	3.4565
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897021
BRD-K06220918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11618
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.051091
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956661
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.43083
methylcrotonoyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.271
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Response to selective serotonin reuptake inhibitors in depression	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08246
BRD-K79568363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47172
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_21-Supplementary_Table_21_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_TCGA_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Caov-3	GDSC Cell Line Gene Expression Profiles	1.0	2.18128
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04836
ESRRA	ENCODE Transcription Factor Targets	1.0	null
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23247
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64093
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-3.xlsx-shared_downregulated-Genes_downregulated_in_the_absence_of_FOXO3_in_GSCs_and_aged_NSCs_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
BRD-K58066822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18906
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-dORF6_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.24807
Perturb_8639_KO_Fndc5_SRP319261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.9373
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96032
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1B	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07522
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868627
K562_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151797
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3542
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.14263
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35801
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinocerebellar ataxia with axonal neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.5065
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1513
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18791
BRD-K17040651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37616
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7841
Juvenile Myoclonic Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30945
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20815
BRD-K55852567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41846
BRD-K87080934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05821
K562_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149017
adolescence-adult electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69088
DU145	DepMap CRISPR Gene Dependency	1.0	2.58408
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21488
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0676
X31(H3N2)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10984
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84292
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37058
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974409
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22615
JUN	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74537725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71339
PMC11947124-41419_2025_7562_MOESM1_ESM.docx-119-ENSG00000198040_ZNF84	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6873-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancuronium bromide-7329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09345
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826964
CEBPD	ENCODE Transcription Factor Targets	1.0	null
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
metaphase	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830532
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2424
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91954
SIN3A	ENCODE Transcription Factor Targets	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.888095
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43786
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10212
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.81639
TFEB	ChEA Transcription Factor Targets	1.0	null
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76723
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60689
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44108
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Up_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73402542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76769
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73297
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41548770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6363
TEAD4_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55501
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.9772
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
withaferin A-4554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81541
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25125
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246071
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.719965
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68178
mebendazole-3671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940101
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78313
BL2786 (PSMC5)	NURSA Protein Complexes	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885221
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3909
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2808
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22349
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MJ-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10260_KO_Esrrg_SRP119935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.58284
20937356-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.08761
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93017276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24808
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear exosome targeting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.314089
FB-56-SR65_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202426
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845753
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41392
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05679
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62141
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267833
BRD-K19829092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16832
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376831
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30945
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67992
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
sirolimus_homo sapiens_gpl8300_gds3603	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22829
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.64743
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.10548
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831515
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926244
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23958
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889878
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951083
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4579
GATA3	ENCODE Transcription Factor Targets	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833454
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852292
enlarged submandibular lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
independent	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979888
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-15-YU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219739
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70376
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63408
BRD-K53443165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6958
CRCGN014_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18652
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637656
CHAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15658
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38297
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51140037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3443
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.95906
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
EGR1	ENCODE Transcription Factor Targets	1.0	null
ISTMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57516
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32687
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82985
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36488
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04682
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6066
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45172
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03257
6549_POLR2H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16351
SB-228357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05047
BRD-K45472595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1285
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2052	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82636
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.34035
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.81436
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20525
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62418
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36623
sex chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.638861
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29471
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958056
Disease of mental health	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0656
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25867
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2088
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02828
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95941120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35469
CHIC2	Pathway Commons Protein-Protein Interactions	1.0	null
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984473
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13523
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FXR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47391428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74981
HMC18	DepMap CRISPR Gene Dependency	1.0	3.28816
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10702
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45892
cefazolin-2564	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07706
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06417
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981951
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35242
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894882
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10444
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5072
CORL23	DepMap CRISPR Gene Dependency	1.0	2.35172
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06519744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16386
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840485
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03121
gm00639	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A96536816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27205
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00982
ZNF263	ENCODE Transcription Factor Targets	1.0	null
HCC2218_BREAST	CCLE Cell Line Proteomics	1.0	2.90007
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83834
dorsolateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73241
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33614
FOSL2	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3183
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
aminoglutethimide-7463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78674
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907393
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831524
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90009
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46637
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19027
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12225
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20649
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06435
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.01587
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.93368
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.192
enlarged axillary lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.977044
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201995
K562	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02329600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30056
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FLI1	ENCODE Transcription Factor Targets	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41866
CMG complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
6548_POLR2G_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.542064
SOX2-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20414
corl279	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78981
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05182
AD-86-ES28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402891
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63270352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71458
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924454
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0605
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847051
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06572
NUP210	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06454
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34528
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11679
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49361
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02768
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894999
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57778
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11921
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27389
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7998
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4918
Autosomal dominant microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
protein binding	GO Molecular Function Annotations 2015	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04614
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VI-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99513
bufexamac-5090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919234
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.573
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40513
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904325
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05605
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623183
NFATC1	ENCODE Transcription Factor Targets	1.0	null
TGW	GDSC Cell Line Gene Expression Profiles	1.0	2.18499
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57684
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24822
K562_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168737
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36432
STAT1	ENCODE Transcription Factor Targets	1.0	null
K562_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168027
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.98359
BRD-K67905771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19818
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04649
premature death	MPO Gene-Phenotype Associations	1.0	null
FOSL1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CJM	CCLE Cell Line Gene Expression Profiles	1.0	1.4792
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24337237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39284
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S0-EE-Y6Y9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264193
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.863
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16278
BRD-K34169251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5429
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-12T	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50411
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02663
daunorubicin-7511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042261
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55293
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31646
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957174
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21226
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal hematopoietic system morphology/development	MPO Gene-Phenotype Associations	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DNA topoisomerase, type IA, DNA-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
abnormal male meiosis	MPO Gene-Phenotype Associations	1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1168
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11672
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13868
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42692
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936777
Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29101
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282483
BRD-K71538933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31488
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30307
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028253
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T5-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250059
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94744
BRD-K83276573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86853
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210150_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174655
Perturb_13439_KD_Myb_SRP119047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
3916_HOXC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.50172
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951332
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94439911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11078
iiibeta	GeneRIF Biological Term Annotations	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71575663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22673
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37949
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K24220535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24542
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253908
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840209
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.04794
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Iniparib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158438
positive	GeneRIF Biological Term Annotations	1.0	null
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	0.494133
BRD-K66110520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0334
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K10288935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27536
predictor	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.05015
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903058
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93223
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
SNU182	CCLE Cell Line Gene Expression Profiles	1.0	1.63496
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913417
mephenesin-3675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.51
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5639
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00073
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10921
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76467
OACM5-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.08391
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIGF_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a72	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_DDR_Genes_NOT_HNSCCHNSCC_DDP_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11989
abnormal lung morphology	MPO Gene-Phenotype Associations	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03026
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57168
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375106
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47307
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
9962_ZBED2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.620709
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02986
BRD-K88179337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32147
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39485
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348745
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60724
BRD-K30977850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56553
DNA recombination	GO Biological Process Annotations 2025	1.0	null
CAL-12T	GDSC Cell Line Gene Expression Profiles	1.0	2.87071
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77375
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328055
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02144
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7235
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44616
col7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07974
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_TMP195_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185725
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09633
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847069
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Aicardi-Goutieres syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Juvenile myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0424
adult ovary	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.00561
DNA topoisomerase III-beta-TDRD3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.244
HCMV_24Hour_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70384
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68473
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44641066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72809
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.729018
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89414
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4731
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K27858225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12156
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60454544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2175
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18904
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9011
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91897530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20718
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385166
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765314
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972169
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	3.04549
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343469
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126621,GSE126920_1_v_4_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90603
BRD-K48406740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44624
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4463
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930217
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850464
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92338
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1382
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18423
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	0.917047
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.24786
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99095
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33261
K562_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189246
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88146
abnormal axillary lymph node morphology	MPO Gene-Phenotype Associations	1.0	null
QGP1_PANCREAS	CCLE Cell Line Proteomics	1.0	5.60186
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43625
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07631
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5375
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940235
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41322
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14132
CHD8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
against	GeneRIF Biological Term Annotations	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40011
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased litter size	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.64186
BRD-K41189799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01969
fursultiamine-6630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9932
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09203354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27686
KBM-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
4957_MED7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.602345
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600819
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89832
SIX5	ENCODE Transcription Factor Targets	1.0	null
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060342
BB-93-VT73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.78561
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09055
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42031
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59335919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69237
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14034
RBBP5	ENCODE Transcription Factor Targets	1.0	null
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04742
germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.749579
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	1.0	1.08479
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04123
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13929
abnormal spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15583
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT4	CCLE Cell Line Gene Expression Profiles	1.0	1.69659
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3315
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A47428621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15395
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16288011-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K89364982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55365
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.889299
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91274
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00631
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ST486	GDSC Cell Line Gene Expression Profiles	1.0	1.45924
A-CA-04-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.25343
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0835
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06818
cyclic adenosine monophosphate-3531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607123
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26431
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89562
BRD-K74091626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34449
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rolitetracycline-6731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32425
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59462
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213142
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63131
dna	GeneRIF Biological Term Annotations	1.0	null
altretamine-6467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.41436
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.02396
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.65954
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860285
Psychotic disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.875818
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03334
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962128
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92292
BRD-K21753319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64985
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.610417
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29605
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972057
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91734
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07164
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56671
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18163
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kmoe2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03366
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.00256
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.24433
GABPA	ENCODE Transcription Factor Targets	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859325
essential	GeneRIF Biological Term Annotations	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59517185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37055
BALL-1	GDSC Cell Line Gene Expression Profiles	1.0	1.79551
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050862
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21466
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Core mediator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
BL4938 (TRIM56)	NURSA Protein Complexes	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01189
sertaconazole-4475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15282657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78875
Cytoplasmic stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.66
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.07381
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSC3	DepMap CRISPR Gene Dependency	1.0	3.16958
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
artemisinin-7247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5964
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.6563
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amantadine-3280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886803
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42188
GTEX-P78B-2526-SM-3P5ZY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06998
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11383
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09431
ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.835198
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17187
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07486
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25207
benzathine benzylpenicillin-7359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.68891
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50389
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937674
MEF2A	ENCODE Transcription Factor Targets	1.0	null
K562_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170182
BRD-K58892587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30084
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0835
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K70148257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53449
BRD-K45537529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46605
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.71723
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10522
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37368
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52081
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319582
0317956-0000-4331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826089
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83926
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33748
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.21162
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14048
BL5036 (CHD8)	NURSA Protein Complexes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleosomal methylation activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
Hyperplasia	CTD Gene-Disease Associations	1.0	1.2208
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04502
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85777
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2013
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53559
abnormal spleen size	MPO Gene-Phenotype Associations	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.079
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.56733
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52176
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32071
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54494
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A204	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56612
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU478	DepMap CRISPR Gene Dependency	1.0	4.53025
BRD-K85633971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54743
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.244
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.60951
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9491
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82229
GRN	Pathway Commons Protein-Protein Interactions	1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18859
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924454
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23822
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20266
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8132
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3617
BRD-K87532481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75173
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61857
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reduces	GeneRIF Biological Term Annotations	1.0	null
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.39963
NALM19	CCLE Cell Line Gene Expression Profiles	1.0	1.40373
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.36486
BRD-K36726853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63069
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44312
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19155
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84038
Ribonuclease H2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
K562_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175401
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8653_TAF12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.651217
PHF8	ENCODE Transcription Factor Targets	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06775
SW954	DepMap CRISPR Gene Dependency	1.0	2.4545
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43238
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fanconi anemia pathway	KEGG Pathways 2026	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.11655
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56189
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16162
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18968
JB-60-JM38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203392
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1022
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
SKMM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43278
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43429
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PEO-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01837
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958953
BRD-K26399271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.61912
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bambuterol-7239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12787
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41482
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6493-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933713
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29605
6801_PRPF4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.26313
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05859
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27011
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875733
BRD-K01263144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33636
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10767
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11413
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883856
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
5074_MIIP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.587917
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05178
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882923
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835617
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10301055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53025
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22985
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.628
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27811
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prosopagnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
marker	GeneRIF Biological Term Annotations	1.0	null
ZM-226600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25781
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.83916
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal peripheral lymph node morphology	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859777
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05279
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
abnormal pancreatic islet morphology	MPO Gene-Phenotype Associations	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13832
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K10513366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58655
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.938634
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27237
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21158
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.968
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06496
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10126
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74558
15604209-Table2b	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84428
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04606
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01267
BRD-K36737730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4425
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894374
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Myocardial Infarction	dbGAP Gene-Trait Associations	1.0	0.017447
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-8117-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10371
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Slx1-Slx4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01778
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
abnormal kidney morphology	MGI Mouse Phenotype Associations 2023	1.0	null
K562_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169692
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.531062
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165753
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946806
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88317
BRD-K98455041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66791
reduced fertility	MPO Gene-Phenotype Associations	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041856
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40944
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970674
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03659
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
benzethonium chloride-7207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.18685
chr22_21978690_G_C_b38	GTEx eQTL 2025	1.0	1.05253
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
PML	ENCODE Transcription Factor Targets	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.586562
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7023
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34699
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234114
niflumic acid-7430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNA topological change	GO Biological Process Annotations 2023	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39657
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3536
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.975991
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929177
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.901383
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64942
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10717
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38173
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreatic islet hyperplasia	MGI Mouse Phenotype Associations 2023	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01277
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05622
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14623
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68884
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9031
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87888
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
FA-92-JL46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226507
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983699
BRD-K04462989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06097
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52234
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.986157
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47218
SPI1	ChEA Transcription Factor Targets	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12418
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984473
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23734
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26738
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70148902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86674
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Protocadherin-mediated cell adhesion and signaling	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39309
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29313
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07267
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29516
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6627
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12233
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K85500722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31736
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78824
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37808
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43268
SREBF2	ENCODE Transcription Factor Targets	1.0	null
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.73003
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23925
BCL3	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48414
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331706
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56384677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05157
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397234
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.698276
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42589
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04419
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87432
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
enlarged axillary lymph nodes	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03486
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871636
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.649848
KASUMI6	CCLE Cell Line Gene Expression Profiles	1.0	1.48758
TCF4	ChEA Transcription Factor Targets	1.0	null
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1155
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-ATF2_UP_V1_DN-Gene_name_ATF2	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-57-AZ77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254795
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842352
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
BL3918 (PPP1CA)	NURSA Protein Complexes	1.0	null
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.935
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9228
ZNF274	ENCODE Transcription Factor Targets	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824697
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92394
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51738
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal salivary gland morphology	MPO Gene-Phenotype Associations	1.0	null
quinpirole-3539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23404017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78267
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893435
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862732
cefazolin-3426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
4152_INTS7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.03884
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19986
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06493
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928604
methoxsalen-6661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LPS6	DepMap CRISPR Gene Dependency	1.0	3.31439
trioxysalen-6078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41251
STAT5A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87044635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11242
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34388
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47848
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89641
SNU626	DepMap CRISPR Gene Dependency	1.0	3.09569
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH838	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83086
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
estrone-4993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56942203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16719
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266988
BL9641 (TDRD3)	NURSA Protein Complexes	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17505
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13929
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39642
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16237
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5433
HN	CCLE Cell Line Gene CNV Profiles	1.0	1.36203
8680_TANGO6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.788913
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858783
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272014
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040421
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34004
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861511
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K07336866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35558
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.90458
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09793
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.434
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29404
PMC12721900-jci-136-187998-s161.xlsx-Flag-ETS1_vs_vector-Gene_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596994
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992852
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44586
SOX2	ChEA Transcription Factor Targets	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11295
Ruijs-Aalfs syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2372
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826992
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tocainide-4838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	6.61475
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.781821
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K-562	COSMIC Cell Line Gene CNV Profiles	1.0	2.09628
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944905
TEAD4	ENCODE Transcription Factor Targets	1.0	null
K562_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014939
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04952
deferoxamine-3417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56357490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01757
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24556
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18509
memantine-7354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
promotes	GeneRIF Biological Term Annotations	1.0	null
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.74165
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rothmund-Thomson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
BRD-K09131889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1561
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.994931
MET_knockout_250_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77839
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039764
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04294
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44444
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16756
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K97962579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42209
4994_METTL16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513389
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68171
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.94328
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59171
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC2A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79373
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25091
DNA topoisomerase, type IA, central	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34768
DNA topoisomerase, type IA, active site	InterPro Predicted Protein Domain Annotations	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6264
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69715817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62063
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45056
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08662
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84768
Kinetoplastid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24723
adrenosterone-5464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42943
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27515
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_proteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23456
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0921
BRD-K14732209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54193
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lb4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
FAM96A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8883456__F6	PFOCR Pathway Figure Associations 2024	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11373
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43969
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24946605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6229
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBGCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24887
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17449
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4872
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
IA-27-CK10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259903
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17074
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30591
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830585
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRC-MELG	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.08391
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72519034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59824
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27599
SRF	ChEA Transcription Factor Targets	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04416
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227837
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.793547
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	2.32884
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68558
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997455
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937906
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19372
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923861
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0536
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64278
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.30792
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11116
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08446
DJM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
myocardial infarction	GAD Gene-Disease Associations	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.6452
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37368
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45609
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00376
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52559
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null