association dataset threshold value standardized value Gonadotrophic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.393 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.834971 SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 1.39203 small molecule binding GO Molecular Function Annotations 2015 1.0 null Opiate dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.22 tph1 GeneRIF Biological Term Annotations 1.0 null EPOP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9123 Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles 1.0 3.27063 phenol-containing compound biosynthetic process GO Biological Process Annotations 2023 1.0 null Tryptophan metabolism(Mus musculus) WikiPathways Pathways 2014 1.0 null SEMA3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75669 Hydrogen Peroxide CTD Gene-Chemical Interactions 1.0 null 5-Hydroxy-tryptophan MW Enzyme Metabolite Associations 1.0 null similarly GeneRIF Biological Term Annotations 1.0 null clathrin-coated vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.43617 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89835 PTPN23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45798 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.93687 Allergic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.667 Colonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.685 novelty GeneRIF Biological Term Annotations 1.0 null possible GeneRIF Biological Term Annotations 1.0 null Enteric muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.187 blood-brain barrier TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.642 MCF10A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.626179 KLE DepMap CRISPR Gene Dependency 1.0 4.59323 GSE149264,GSE149267_9_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIDS Susceptibility Pathways(Homo sapiens) WikiPathways Pathways 2014 1.0 null Cerebrovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.542 Substantia nigra TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.534 BRD-K52300725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26718 GTEX-XV7Q-1326-SM-4BRWM GTEx Tissue Sample Gene Expression Profiles 1.0 2.49496 GSE136232,GSE136234_0_v_1_zpbp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22001 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971195 Sepiapterin reductase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.643 Cues HuGE Navigator Gene-Phenotype Associations 1.0 null MFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07267 Perturb_4868_KO_NEUROG3_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.4475 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.915779 GJD2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00455464 Hypertension CTD Gene-Disease Associations 1.0 1.14166 CORL279 DepMap CRISPR Gene Dependency 1.0 2.39616 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.40366 Hypoparathyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 MED13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79345 GSE207582_4_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null TESK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95547 BRD-K06431647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65424 indolalkylamine biosynthetic process GO Biological Process Annotations 2015 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855082 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2638 anger-related traits GAD Gene-Disease Associations 1.0 null OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.23444 Liver cirrhosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 BRD-K26127722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20486 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.825 Brain Lower Grade Glioma_LGG_TCGA-HT-7478-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.223419 eosinophilia-myalgia syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.340906 PITX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86488 anxiety GeneRIF Biological Term Annotations 1.0 null JHH5 CCLE Cell Line Gene CNV Profiles 1.0 1.45087 KMM1 CCLE Cell Line Gene Mutation Profiles 1.0 null ZNF276 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10005 pain agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.799513 GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.10361 Perturb_8941_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.392 CP50-MEL-B COSMIC Cell Line Gene Mutation Profiles 1.0 null kinetic GeneRIF Biological Term Annotations 1.0 null CDC26 Pathway Commons Protein-Protein Interactions 1.0 null Neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.069 GTEX-NL4W-0011-R9a-SM-2I3G1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.874127 Basophil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.495 BRD-K06279388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3178 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.56003 FAM20C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87551 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null PROKR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72705 GTEX-V955-1026-SM-4JBHO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879359 PPFIA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92597 acute t cell leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.258417 Succinate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.346 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO Molecular Function Annotations 2025 1.0 null B4GAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67524 coding GeneRIF Biological Term Annotations 1.0 null urine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.234302 recessive GeneRIF Biological Term Annotations 1.0 null Dyskeratosis Congenita DisGeNET Gene-Disease Associations 1.0 null GTEX-S7SF-0626-SM-4AD4V GTEx Tissue Sample Gene Expression Profiles 1.0 1.2713 spinal column TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.558059 inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859684 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906649 airway GeneRIF Biological Term Annotations 1.0 null SLC27A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02024 Bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.544 Antisocial Personality Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Medial amygdalar nucleus, posterodorsal part, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08186 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.414 SDF4 Pathway Commons Protein-Protein Interactions 1.0 null yolk COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.246769 Fibrosis CTD Gene-Disease Associations 1.0 1.05757 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42588 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.04428 pharmacogenomic GAD High Level Gene-Disease Associations 1.0 0.305726 Conduct Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null AIFM2 Pathway Commons Protein-Protein Interactions 1.0 null small intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.797708 decreased cardiac stroke volume MPO Gene-Phenotype Associations 1.0 null GSE94011_2_v_1_pias3_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.11106 MX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10214 patch GeneRIF Biological Term Annotations 1.0 null hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058742 substance abuse DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161523 TRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48413 NKX2-5-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7458 studies GeneRIF Biological Term Annotations 1.0 null ZC3H18 Pathway Commons Protein-Protein Interactions 1.0 null Macropinocytic cup COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.536 significant GeneRIF Biological Term Annotations 1.0 null GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73036 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854256 HS706T CCLE Cell Line Gene Expression Profiles 1.0 1.41858 Preosteoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.981 tph GeneRIF Biological Term Annotations 1.0 null GTEX-PWOO-2526-SM-2S1PG GTEx Tissue Sample Gene Expression Profiles 1.0 0.829418 GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles 1.0 0.854076 Mesenteric vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Pharyngeal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.927 does GeneRIF Biological Term Annotations 1.0 null Insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.154 organonitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04518 MNAT1_Deficiency - Ablation_GDS2561_690_mouse_Heart - 4 week old GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.203 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94528 DDC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00501295 USP13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51321 POLR1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3381 GTEX-POMQ-0426-SM-3P61G GTEx Tissue Sample Gene Expression Profiles 1.0 1.44255 nuclear replication fork COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.160863 environment GeneRIF Biological Term Annotations 1.0 null Cerebrospinal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.794 Ulcerative Colitis DisGeNET Gene-Disease Associations 1.0 null GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02337 BRD-K18149487 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92818 BRD-K78007953 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07023 CRCGN017_MCF10A.WT.HP_24H:K18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.024 effects GeneRIF Biological Term Annotations 1.0 null primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.967078 catalytic GeneRIF Biological Term Annotations 1.0 null Schizophrenic Psychology HuGE Navigator Gene-Phenotype Associations 1.0 null Perturb_14229_KO_Kdm2b_SRP060647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 nicotine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.797872 Exocytic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.825 medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1562 BRD-K44932450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42337 suicide ; mood disorders GAD Gene-Disease Associations 1.0 null Adrenal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.201 Suicidal DisGeNET Gene-Disease Associations 1.0 null fibroblast-like synoviocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.178 rs6311 GeneRIF Biological Term Annotations 1.0 null abnormal blood circulation MPO Gene-Phenotype Associations 1.0 null GTEX-XAJ8-0526-SM-47JYK GTEx Tissue Sample Gene Expression Profiles 1.0 0.860291 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18353 SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.980217 GTEX-R55E-1126-SM-48FDZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.02152 BRD-K73357447 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5843 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856503 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38027 rectum_8a HPA Tissue Sample Gene Expression Profiles 1.0 1.28982 BRD-K16695519 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86233 response to stress GO Biological Process Annotations 2015 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54 LOX Pathway Commons Protein-Protein Interactions 1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22522 Central amygdaloid nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.55 GATA1_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC25A10 Pathway Commons Protein-Protein Interactions 1.0 null SW1463 CCLE Cell Line Gene Expression Profiles 1.0 1.40452 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.281 BRD-K60837711 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33425 GCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84082 GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75833 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.18 peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178145 Intestinal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.006 Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.056 GSE248045,GSE248046_6_v_1_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null brain GeneRIF Biological Term Annotations 1.0 null largest GeneRIF Biological Term Annotations 1.0 null Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.397 Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46343 abnormal serotonin level MGI Mouse Phenotype Associations 2023 1.0 null Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01276 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.38992 TMEM245 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85766 BRD-K12460934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08303 Perturb_3745_KO_Usp8_SRP301242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.373118 Ec TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.776 abnormal hormone level MPO Gene-Phenotype Associations 1.0 null mammary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36825 TRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7268 Subarachnoid space TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.789 KCNG3 Pathway Commons Protein-Protein Interactions 1.0 null Acidocalcisome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.616 GSE149903_6_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures -1.0 null CRCGN015_MCF10A.TP53.M_24H:K11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1208 BRD-K58644442 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04786 olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.654212 Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13442 Hypertension, Pulmonary CTD Gene-Disease Associations 1.0 2.88009 pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.31694 GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null stool GeneRIF Biological Term Annotations 1.0 null KYAE1 DepMap CRISPR Gene Dependency 1.0 4.12199 consistent GeneRIF Biological Term Annotations 1.0 null rett syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.324458 PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null GSE225901_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Pathological gambling DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 FERMT3 Pathway Commons Protein-Protein Interactions 1.0 null less GeneRIF Biological Term Annotations 1.0 null GALT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62708 HUT102 CCLE Cell Line Gene Mutation Profiles 1.0 null lateral geniculate body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461078 IMPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1261 Bone remodeling disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.818 ITGA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7327 FAM83F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53553 t-cell leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.13947 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50363 Perturb_12081_KO_Stat5_SRP060232 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.4235 DUSP1_KO_GDS1606_775_mouse_Spleens GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-A25184723 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08916 PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36629 SW948 DepMap CRISPR Gene Dependency 1.0 2.73107 EAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37889 ZNF626 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03619 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57175 smallintestine_4c HPA Tissue Sample Gene Expression Profiles 1.0 0.996292 higher GeneRIF Biological Term Annotations 1.0 null FOXD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27253 layer 6 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05226 GTEX-RTLS-2626-SM-46MUJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.931718 duodenum HPA Tissue Gene Expression Profiles 1.0 0.878513 ARHGAP45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27902 Cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.933 H3255 COSMIC Cell Line Gene Mutation Profiles 1.0 null parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045884 Food allergy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.168 Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Premenstrual Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null Arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.481 BRD-K55800245 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22075 Chronic fatigue syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 BRD-K81277520 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21006 DNAJB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60007 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.828515 GTEX-U3ZN-2026-SM-4DXUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.11285 ATM Pathway Commons Protein-Protein Interactions 1.0 null BRD-K94506829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09891 Colonic epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.698 GNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55178 BRD-K07770425 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88387 Vagus nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.208 anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4107 BRD-K71647210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47167 scoliosis GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1182 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.53737 t52-hippocampus_male_8w MoTrPAC Rat Endurance Exercise Training -1.0 -3.42389 GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.918025 SAOS-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null receptors GeneRIF Biological Term Annotations 1.0 null mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.841188 GTEX-XMD1-0011-R2B-SM-4AT5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30323 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.287 cannot GeneRIF Biological Term Annotations 1.0 null Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.292 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC14 CCLE Cell Line Gene Expression Profiles -1.0 -1.45639 TE5 DepMap CRISPR Gene Dependency 1.0 3.96067 Bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.975 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.21486 ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41488 provides GeneRIF Biological Term Annotations 1.0 null decreased cardiac stroke volume MGI Mouse Phenotype Associations 2023 1.0 null major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.406051 MGAT2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00597354 irritable GeneRIF Biological Term Annotations 1.0 null empirical GeneRIF Biological Term Annotations 1.0 null BRD-K52592505 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.45667 BRD-K81669067 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.72866 BRD-K12328371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22146 TOX_01_332 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.89244 rectum_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.20026 GTPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.968 Serotonergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.097 yolk granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.253653 asb GeneRIF Biological Term Annotations 1.0 null head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 superficial stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42656 PMC7461571__F2 PFOCR Pathway Figure Associations 2023 1.0 null Medial longitudinal fasciculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.01 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34281 NCI-H82 GDSC Cell Line Gene Expression Profiles 1.0 2.39148 RUNX2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K32146668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51122 Pulmonary Hypertension DisGeNET Gene-Phenotype Associations 1.0 null Superior temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.966 Signaling by NTRKs Reactome Pathways 2024 1.0 null ABCA1 Pathway Commons Protein-Protein Interactions 1.0 null DEXFENFLURAMINE DGIdb Drug Targets 2026 1.0 1.10275 r1 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19663 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4657121__F1 PFOCR Pathway Figure Associations 2024 1.0 null lateral ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.873172 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.75816 RAB42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43168 NR4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28866 GINS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31882 young GeneRIF Biological Term Annotations 1.0 null Rectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.834 chitin-based extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.675 whether GeneRIF Biological Term Annotations 1.0 null GPRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66553 ZBTB40 Pathway Commons Protein-Protein Interactions 1.0 null GSE179138_3_v_1_lama4_mouse RummaGEO Gene Perturbation Signatures 1.0 null DCLRE1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80273 smb GeneRIF Biological Term Annotations 1.0 null GTEX-VUSG-2826-SM-4KKZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.883124 Paranoid schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.222 Pharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.706 GATA2_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null correlation GeneRIF Biological Term Annotations 1.0 null Abdominal aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.8 replisome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.136307 periventricular stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.58995 TSKU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03604 BRD-K31462164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07088 Lysosomal storage disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.788 BRD-K50859531 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06013 Cell lineage map for neuronal differentiation WikiPathways Pathways 2024 1.0 null Basal forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.117 MDAMB436 CCLE Cell Line Gene Mutation Profiles 1.0 null PHLDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82281 hostile GeneRIF Biological Term Annotations 1.0 null PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951307 disease GWASdb SNP-Disease Associations 1.0 0.023637 morphine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.163317 nucleotide GeneRIF Biological Term Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.888739 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.18989 Bile duct adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.068 ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null stomach_a HPA Tissue Sample Gene Expression Profiles 1.0 0.824097 FAM210A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48161 PMC4404183__F2 PFOCR Pathway Figure Associations 2024 1.0 null BRD-K13402127 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20666 GEMIN5 Pathway Commons Protein-Protein Interactions 1.0 null adults GeneRIF Biological Term Annotations 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4957 Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ammonium ion metabolic process GO Biological Process Annotations 2015 1.0 null ACYP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09156 Alzheimer Disease DisGeNET Gene-Disease Associations 1.0 null mast cell neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.47682 Vitiligo DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 liminal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07278 asperger syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.319363 JIMT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null migraine GAD Gene-Disease Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K47582411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19438 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54434 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73689 PMC8064323__F10 PFOCR Pathway Figure Associations 2023 1.0 null BRD-K46890865 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5543 BRD-K73688688 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00025 profiles GeneRIF Biological Term Annotations 1.0 null Primary pulmonary hypoplasia_Lung Tissue_GSE1363 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.68586 Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EGFR_OE_GDS1925_167_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 6-FLUOROTRYPTOPHAN DGIdb Drug Targets 2026 1.0 1.65412 GPR158 Pathway Commons Protein-Protein Interactions 1.0 null WASHC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60736 BRD-K25982056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0478 ML-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.565 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRTFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94999 BRD-K15898103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39825 GTEX-XUYS-0426-SM-47JX3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.23204 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00129 amygdaloid complex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.910996 sequence GeneRIF Biological Term Annotations 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.860265 harm GeneRIF Biological Term Annotations 1.0 null BRD-K23075656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32903 GSE139455_7_v_6_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14336 NPIPB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81265 Lateral element COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 respiratory distress MPO Gene-Phenotype Associations 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62143 GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37269 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.16276 htr6 GeneRIF Biological Term Annotations 1.0 null mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24214 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.105 BRD-K11013450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16383 GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064748 rs1118997 GeneRIF Biological Term Annotations 1.0 null PPIP5K2 Pathway Commons Protein-Protein Interactions 1.0 null Tetrahydrobiopterin (BH4)-deficient hyperphenylalaninemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.971332 Necrosis CTD Gene-Disease Associations 1.0 1.81243 IL9 MSigDB Cancer Gene Co-expression Modules 1.0 null Perturb_8956_KO_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE152432_3_v_2_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null some GeneRIF Biological Term Annotations 1.0 null GSE228263_0_v_1_elesclomol_human RummaGEO Drug Perturbation Signatures 1.0 null HCFC2 Pathway Commons Protein-Protein Interactions 1.0 null Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null CSF1 Pathway Commons Protein-Protein Interactions 1.0 null immunodominant GeneRIF Biological Term Annotations 1.0 null BRD-K76508844 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50429 GTEX-S4P3-1826-SM-3K2AL GTEx Tissue Sample Gene Expression Profiles 1.0 1.04837 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00821 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02717 anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.21262 CENPV Pathway Commons Protein-Protein Interactions 1.0 null GSE148066,GSE157787_11_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null biliary tract cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063904 CHRDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40773 GTEX-R53T-0226-SM-48FEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10785 GSE173873_10_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null addison's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.656837 CEP55 Pathway Commons Protein-Protein Interactions 1.0 null Myenteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.364 ARMC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98147 RODATRISTAT ETHYL DGIdb Drug Targets 2026 1.0 6.6165 genotypic GeneRIF Biological Term Annotations 1.0 null inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079433 single-organism developmental process GO Biological Process Annotations 2015 1.0 null PMC9168430__F3 PFOCR Pathway Figure Associations 2024 1.0 null Neurosecretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.746 RASGRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91374 GFPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44816 GTEX-XQ8I-2126-SM-4BOOM GTEx Tissue Sample Gene Expression Profiles 1.0 1.02655 EFM-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null reduces GeneRIF Biological Term Annotations 1.0 null post GeneRIF Biological Term Annotations 1.0 null ncih727 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.05 BRD-K13265046 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05112 GTEX-XQ8I-1326-SM-4BOPV GTEx Tissue Sample Gene Expression Profiles 1.0 1.31267 trial GeneRIF Biological Term Annotations 1.0 null SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0894 allele GeneRIF Biological Term Annotations 1.0 null BRD-K72967213 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.212 CRCGN012_HEPG2_24H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.72236 depressive disorder, major; bipolar disorder GAD Gene-Disease Associations 1.0 null GTEX-T6MN-0426-SM-32PMF GTEx Tissue Sample Gene Expression Profiles 1.0 1.4549 GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01578 KALRN Pathway Commons Protein-Protein Interactions 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.830279 TGBC1TKB DepMap CRISPR Gene Dependency 1.0 2.28217 Depressed Mood DisGeNET Gene-Phenotype Associations 1.0 null PCBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2233 Kidney failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 PMC4423366__F1 PFOCR Pathway Figure Associations 2023 1.0 null ZNF329 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17551 FOXA2 ENCODE Transcription Factor Targets 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.784388 GTEX-P4PP-0426-SM-3NM9H GTEx Tissue Sample Gene Expression Profiles 1.0 2.00059 TMUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98075 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37934 intrahepatic cholangiocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.13387 polymyxin b sulfate_escherichia coli_gpl3154_gse31140 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null adrenal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.233446 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868064 Intrinsic component of synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.571 dorsolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22906 one GeneRIF Biological Term Annotations 1.0 null UGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02426 TRPM1 Pathway Commons Protein-Protein Interactions 1.0 null thus GeneRIF Biological Term Annotations 1.0 null CCDC115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20875 SMPDL3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8931 Skin Neoplasms CTD Gene-Disease Associations 1.0 1.61713 Hepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 CRCGN017_MCF10A.TP53.M_24H:N16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.184 RNF214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82647 H4C15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66766 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RPL26L1 Pathway Commons Protein-Protein Interactions 1.0 null OBSCN Pathway Commons Protein-Protein Interactions 1.0 null state GeneRIF Biological Term Annotations 1.0 null PSMD2 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 Enterocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.057 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null gastrointestinal system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.10571 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62393 GSE225656_2_v_3_tsc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60557 Interfascicular region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.895 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.698216 adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.21268 CW2 CCLE Cell Line Gene Mutation Profiles 1.0 null Hippocampus minor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.774 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.57008 TMCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81012 osteoporosis-pseudoglioma syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.952 cardiovascular system phenotype MPO Gene-Phenotype Associations 1.0 null analogue GeneRIF Biological Term Annotations 1.0 null ZNF200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36448 bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.239799 Gambling HuGE Navigator Gene-Phenotype Associations 1.0 null Bile duct disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 GTEX-S4UY-0426-SM-3K2AF GTEx Tissue Sample Gene Expression Profiles 1.0 0.838398 Sclerosteosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 GABRR1 Pathway Commons Protein-Protein Interactions 1.0 null allelic GeneRIF Biological Term Annotations 1.0 null GSE152937_12_v_7_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null Longitudinal smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.684 SPO11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12058 MT-CO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78704 HK1 Pathway Commons Protein-Protein Interactions 1.0 null TFAP2C JASPAR Predicted Transcription Factor Targets 1.0 null GSE144115_4_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.278 replication fork COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.136151 Anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 CRCGN015_HEPG2_48H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.02045 MYC Pathway Commons Protein-Protein Interactions 1.0 null Obesity HuGE Navigator Gene-Phenotype Associations 1.0 null GSE184210_0_v_3_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null BRD-K55927371 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45669 Trophoblast giant cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 configuration GeneRIF Biological Term Annotations 1.0 null Head muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.485 PMC8064323__F10 PFOCR Pathway Figure Associations 2024 1.0 null mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE132948,GSE132949_2_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.867635 turnover GeneRIF Biological Term Annotations 1.0 null treatment GeneRIF Biological Term Annotations 1.0 null primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.5183 PHIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27313 NPTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43121 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.94507 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K67508052 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13267 Amino acid metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.569 Puberty, Delayed HuGE Navigator Gene-Phenotype Associations 1.0 null Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7316 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.964183 EEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67512 Hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.052 TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC11430468-sciadv.adp2442_sm.pdf-15-SOX12_SOX12 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles 1.0 2.70164 Subcommissural organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.9 anxiety disorder GAD Gene-Disease Associations 1.0 null MPZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65865 nucleoplasm part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050275 GTEX-TMMY-1026-SM-4DXTI GTEx Tissue Sample Gene Expression Profiles 1.0 2.01495 GSE60837_2_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null liver_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.885086 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.74242 SYTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16502 lat1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.517 developmental GAD High Level Gene-Disease Associations 1.0 0.293278 psychiatric GeneRIF Biological Term Annotations 1.0 null Uterine disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5408 LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4429 premenstrual GeneRIF Biological Term Annotations 1.0 null TRIM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82309 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22001 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831094 MRPL46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56171 cholangiocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.121311 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.15052 Oxygen HMDB Metabolites of Enzymes 1.0 null KIAA0319 Pathway Commons Protein-Protein Interactions 1.0 null Guanylate cyclase complex, soluble COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.138 tolerance GeneRIF Biological Term Annotations 1.0 null BRD-K64698855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88009 BRD-K89760040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02821 smoking behavior GAD Gene-Disease Associations 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930052 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rs537 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.961 DHX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00892 epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.156373 BRD-K42650945 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57947 B-cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.198 Bile duct cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 BRD-K18623962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32706 Polycystic Ovary Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null KATNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08879 BRD-K43654313 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39109 childhoodonset GeneRIF Biological Term Annotations 1.0 null BRD-K82112239 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28138 SNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35967 severity GeneRIF Biological Term Annotations 1.0 null includes GeneRIF Biological Term Annotations 1.0 null mucosal mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262304 U-87-MG GDSC Cell Line Gene Expression Profiles -1.0 -1.63835 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.415 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.40653 neuron part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 SLC4A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03133 Pancreatic cystadenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 PALD1 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11112 BB49-HNC GDSC Cell Line Gene Expression Profiles -1.0 -2.03286 thorax TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.503533 medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85542 EXOSC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27937 Despondency DisGeNET Gene-Phenotype Associations 1.0 null SLC18B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78651 cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.744214 enterochromaffin-like cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.451 fenfluramine Guide to Pharmacology Chemical Ligands of Receptors 1.0 null submucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298524 Pancreatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146 synaptic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.40247 secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.231672 URGCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5021 BRD-K50300854 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.35297 periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58066 RDH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4565 Pancreatic islet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.121 rates GeneRIF Biological Term Annotations 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.51141 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4503 astroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06646 Stomodeum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 Colon cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.447 BUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95555 SLC9A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0468 GTEX-S7SF-0526-SM-3K2BC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25756 allergic GeneRIF Biological Term Annotations 1.0 null BRD-K30615964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22137 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null chromosomal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.051524 EOMES ChEA Transcription Factor Targets 1.0 null attention deficit hyperactivity disorder GAD Gene-Disease Associations 1.0 null BRD-K94817443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2217 BRD-K95537020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83518 GSE173873_2_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null CRCGN014_HEPG2_24H:L18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.40747 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03544 chrysin-3106 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Mastocytoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 TIMM17B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88712 CDIPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71672 MCTP2 Pathway Commons Protein-Protein Interactions 1.0 null small intestine GTEx Tissue Gene Expression Profiles 1.0 0.862338 STAMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16019 POLE LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00574312 dissorder GeneRIF Biological Term Annotations 1.0 null ZNF710 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7631 transductionlinked GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LITHIUM CATION DGIdb Drug Targets 2026 1.0 0.153872 GTEX-UPK5-1426-SM-4JBHH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03462 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PHF20 Pathway Commons Protein-Protein Interactions 1.0 null Cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.322 Severe Major Depression With Psychotic Features DisGeNET Gene-Disease Associations 1.0 null BRD-K89230185 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34457 small intestine neuroendocrine neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.05219 organelle LOCATE Predicted Protein Localization Annotations 1.0 null repeat GeneRIF Biological Term Annotations 1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15461 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.73862 rpmi8226 HPA Cell Line Gene Expression Profiles -1.0 -0.928844 BRD-K57476199 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1032 inferior frontal gyrus, orbital part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.919027 hepatopulmonary syndrome; liver cirrhosis GAD Gene-Disease Associations 1.0 null tandem GeneRIF Biological Term Annotations 1.0 null Corpus callosum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.626 ZNF771 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84775 L-erythro-tetrahydrobiopterin HMDB Metabolites of Enzymes 1.0 null CRCGN011_HEPG2_24H:K05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3113 serves GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.978856 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61016 Nucleus preopticus periventricularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 PMC9292562__F4 PFOCR Pathway Figure Associations 2024 1.0 null GSE234340_4_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 18277965-Table4b GeneSigDB Published Gene Signatures 1.0 null 16611997-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.159 Thrombophilia HuGE Navigator Gene-Phenotype Associations 1.0 null Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 CD81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2023 PMC2841835__F1 PFOCR Pathway Figure Associations 2024 1.0 null strabismus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.109751 OTUD4 Pathway Commons Protein-Protein Interactions 1.0 null CRCGN015_HEPG2_48H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.00387 CCNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.76399 s-transferase Phosphosite Textmining Biological Term Annotations 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21443 Median nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.405 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.77232 Corpus albicans TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.787 Anorexia Nervosa HuGE Navigator Gene-Phenotype Associations 1.0 null duodenum_4c HPA Tissue Sample Gene Expression Profiles 1.0 0.882081 Mammary gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.68 U138 BioGPS Cell Line Gene Expression Profiles -1.0 -0.907697 Paneth cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.712 GSE173873_10_v_3_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ureter cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.581606 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058542 HS729 CCLE Cell Line Gene CNV Profiles 1.0 1.34848 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.963335 GSE149903_0_v_7_myd88_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CH25H LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00454316 Hirschsprung's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28141 HS-68 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.615 SF539 BioGPS Cell Line Gene Expression Profiles -1.0 -0.996065 Inferior colliculus, central nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07807 primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042943 Lamina propria TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.86 Serotonergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.816 JHUEM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.50798 C1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4462 Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SPTSSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3408 PI4KA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26115 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.81371 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3174 block GeneRIF Biological Term Annotations 1.0 null PMC5591914__F1 PFOCR Pathway Figure Associations 2024 1.0 null exerts GeneRIF Biological Term Annotations 1.0 null Abdominal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.709 history GeneRIF Biological Term Annotations 1.0 null exocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061224 Floor plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.778 DYNC1H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67025 genotyped GeneRIF Biological Term Annotations 1.0 null CDC7 Kinase Library Serine Threonine Kinome Atlas 1.0 null SH2D2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14153 aaahs GeneRIF Biological Term Annotations 1.0 null BRD-K59870481 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44203 midbrain central gray TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.08899 CHRNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20512 bone GeneRIF Biological Term Annotations 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K13781734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49125 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.06616 GTEX-P4PP-1426-SM-3NM9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.21492 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Alcoholism HuGE Navigator Gene-Phenotype Associations 1.0 null Brain - Cerebellum GTEx Tissue Gene Expression Profiles 2023 1.0 6.68918 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.327 POMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39897 Heart Diseases CTD Gene-Disease Associations 1.0 1.05312 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cocaine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 Heart valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 pineal gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.247852 ICAM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28883 Pulmonary Fibrosis DisGeNET Gene-Disease Associations 1.0 null GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23314 several psychiatric disorders GAD Gene-Disease Associations 1.0 null bipolar disorder GAD Gene-Disease Associations 1.0 null primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19424 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963957 KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.0783 ZDHHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5661 H2AC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41174 MAGEB10 Pathway Commons Protein-Protein Interactions 1.0 null Bipolar Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null BRD-K05074020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2278 GATA1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CNMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02791 KCNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93312 electroconvulsive GeneRIF Biological Term Annotations 1.0 null analyses GeneRIF Biological Term Annotations 1.0 null nb88 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.923 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59571 theileriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.337608 abnormal cardiac output MPO Gene-Phenotype Associations 1.0 null connective tissue cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.698313 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980163 schizophrenia; bipolar disorder; psychoses GAD Gene-Disease Associations 1.0 null varicosity COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.388523 HT115 CCLE Cell Line Gene Mutation Profiles 1.0 null rs6313 GeneRIF Biological Term Annotations 1.0 null within GeneRIF Biological Term Annotations 1.0 null transferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065662 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88757 macroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062536 Metabolism of amino acids and derivatives Reactome Pathways 2024 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.76075 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.773 monocytic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23459 dura mater TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.2559 attempts GeneRIF Biological Term Annotations 1.0 null muscle phenotype MPO Gene-Phenotype Associations 1.0 null GSE119978,GSE180930_6_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Aromatic amino acid hydroxylase, C-terminal InterPro Predicted Protein Domain Annotations 1.0 null STOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64437 GSE160083,GSE160084_2_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null plasticity GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D9-01B-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscularis mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.697 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855082 adulthood GeneRIF Biological Term Annotations 1.0 null CDC25B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66565 drd4 GeneRIF Biological Term Annotations 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1954 BRD-K52202153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13272 agranulocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.227988 Depressive Disorder, Major HuGE Navigator Gene-Phenotype Associations 1.0 null METAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06775 cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.940495 SLC39A14 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00469152 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.830279 enlarged heart MPO Gene-Phenotype Associations 1.0 null bile duct carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.088772 influencing GeneRIF Biological Term Annotations 1.0 null hsa-miR-4483 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.117 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44766 FKBP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65219 CRCGN017_MCF10A.TP53.M_24H:O21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.48215 PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4 Rummagene Transcription Factor Associations 2026 1.0 null GSE202603_3_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures 1.0 null subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87684 Spinal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.853 ATP6V1D Pathway Commons Protein-Protein Interactions 1.0 null physiological GeneRIF Biological Term Annotations 1.0 null endocrine GeneRIF Biological Term Annotations 1.0 null PRR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88194 mood disorders GAD Gene-Disease Associations 1.0 null nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.02679 C18orf21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0916 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367 CROCC Pathway Commons Protein-Protein Interactions 1.0 null ZNF740 Pathway Commons Protein-Protein Interactions 1.0 null PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06142 PMC10535706__F8 PFOCR Pathway Figure Associations 2024 1.0 null Perturb_5387_KO_Isl1_SRP380182 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.70038 eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.700262 BRD-K25039453 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46263 pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.16148 blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054959 gestational diabetes DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.178403 BRD-K55399138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23449 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.827697 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.857889 BRD-K20331065 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25669 major and bipolar depressives GAD Gene-Disease Associations 1.0 null down syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.250311 COLGALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8327 GSK3A_KD_GDS4305_184_human_U937 acute myeloid leukemia cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.TP53.M_24H:P21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.42637 GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Posterior periventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 lewy body dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.378885 BRD-K08927194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06045 BRD-K16988512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2865 KAP1-22055183-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Visceral hump TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 Cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.56 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_9599_KO_Csnk1a1_ERP003394 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 BRD-K60437668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.29707 RFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92001 Peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.171 BL-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.646 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.18851 hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.52331 ADPGK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0636 hypothesis GeneRIF Biological Term Annotations 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20947 Human - Fetal Development - L2 - Stomach-Neuroendocrine cells HuBMAP Azimuth Cell Type Annotations 1.0 null GATA4 ChEA Transcription Factor Targets 1.0 null FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27625 GHITM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49951 TUBA4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4928 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77815 BRD-K87461415 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25811 Perturb_938_KO_Gcgr_SRP238015 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.41046 Spinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.442 PFKFB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36728 Basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.152 cingulate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.278603 SNX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34185 GTEX-Q2AH-2026-SM-2S1PX GTEx Tissue Sample Gene Expression Profiles 1.0 1.34247 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.526341 GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Invertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.655 lipoid proteinosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.400826 Fourth ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.184 DUSP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49197 GTEX-QDVN-2326-SM-2S1PF GTEx Tissue Sample Gene Expression Profiles 1.0 0.944677 aggressive GeneRIF Biological Term Annotations 1.0 null carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.289386 GDAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38578 DIRAS2 Pathway Commons Protein-Protein Interactions 1.0 null attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.8741 BRD-K89923892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39073 dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26565 Diarrhea DisGeNET Gene-Disease Associations 1.0 null Goblet cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.849 AGPAT1 Pathway Commons Protein-Protein Interactions 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61016 abnormal cardiac stroke volume MPO Gene-Phenotype Associations 1.0 null unlikely GeneRIF Biological Term Annotations 1.0 null GTEX-XPT6-2226-SM-4B66R GTEx Tissue Sample Gene Expression Profiles 1.0 0.855804 Axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.836 anterior hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242054 PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD Rummagene Transcription Factor Associations 2026 1.0 null TF1 CCLE Cell Line Gene Expression Profiles 1.0 1.34737 Colitis DisGeNET Gene-Disease Associations 1.0 null diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.824948 amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.670064 SKM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC5575491__F5 PFOCR Pathway Figure Associations 2023 1.0 null C2orf16 Pathway Commons Protein-Protein Interactions 1.0 null Autoimmune polyendocrine syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.434 GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63053 hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.419517 autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.058831 PEX26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5127 fine root TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.37087 PMC7559772__F2 PFOCR Pathway Figure Associations 2024 1.0 null Somatization DisGeNET Gene-Disease Associations 1.0 null LETMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8465 BRD-K28952606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31969 TMEM187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8381 serotonin biosynthetic process GO Biological Process Annotations 2015 1.0 null HEC108 CCLE Cell Line Gene Mutation Profiles 1.0 null SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null together GeneRIF Biological Term Annotations 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.37225 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Tendon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.517 calcium Phosphosite Textmining Biological Term Annotations 1.0 null PAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28707 GTEX-W5WG-2426-SM-4LMI6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11938 Myosin X complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.665 dendritic spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.419252 SYN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22533 nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047168 GTEX-WRHU-0726-SM-3MJFL GTEx Tissue Sample Gene Expression Profiles 1.0 1.24226 Functional Laterality HuGE Navigator Gene-Phenotype Associations 1.0 null Mood Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null primary amino compound biosynthetic process GO Biological Process Annotations 2015 1.0 null USP10 Pathway Commons Protein-Protein Interactions 1.0 null SYF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47305 GTEX-XUZC-1426-SM-4BRV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0698 THY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06086 abnormal cardiovascular system physiology MPO Gene-Phenotype Associations 1.0 null GSE133087_3_v_2_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLTP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89614 salivary gland carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.142009 AMOTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38377 fluoxetine GeneRIF Biological Term Annotations 1.0 null Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19517 autoimmune polyendocrine syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.20093 PRKACA KEA Substrates of Kinases 1.0 null ACADSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15865 concluded GeneRIF Biological Term Annotations 1.0 null GSE128099,GSE128159_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.527569 visual cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.230656 indole-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null Lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.227 REP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55643 Scoliosis, Unspecified DisGeNET Gene-Disease Associations 1.0 null SREK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66371 GSE174701_4_v_3_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Scoliosis HuGE Navigator Gene-Phenotype Associations 1.0 null populationbased GeneRIF Biological Term Annotations 1.0 null THOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11508 disequilibrium GeneRIF Biological Term Annotations 1.0 null 496100671_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.84382 Liver Neoplasms CTD Gene-Disease Associations 1.0 1.41478 locus ceruleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.35086 rbl-2h3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245491 Alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.672 HIST1H2AB Pathway Commons Protein-Protein Interactions 1.0 null E2F1_KD_GDS4094_446_mouse_Mammary tumors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Ileum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.188 updated GeneRIF Biological Term Annotations 1.0 null Bulimia HuGE Navigator Gene-Phenotype Associations 1.0 null Nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.598 HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.712047 PCBP2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZI-1126-SM-3NB1F GTEx Tissue Sample Gene Expression Profiles 1.0 1.77937 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42637 BRD-K43473008 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59653 BRD-K75293299 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.79506 ERMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.76565 OPHN1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K62892366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50692 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 SKPNDW DepMap CRISPR Gene Dependency 1.0 5.40144 SPIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91915 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GSE180200,GSE180201_12_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null L-methionine sulfoximine-2470 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CPXM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8771 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23064 Perturb_3298_KO_E8I_SRP144318 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Cingulate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.572 depressed suicide; suicide due to depression GAD Gene-Disease Associations 1.0 null HOXA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36501 GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures 1.0 null Intestinal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.267 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.29956 PELO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31859 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94511 substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.06774 BRD-K40735917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05713 Mushroom body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.027 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5168 depressive episode, major GAD Gene-Disease Associations 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.998508 COLO684 CCLE Cell Line Gene Expression Profiles 1.0 2.40784 cterminal GeneRIF Biological Term Annotations 1.0 null NOMO2 Pathway Commons Protein-Protein Interactions 1.0 null Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05226 endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SQRDL Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11262 nutritional deficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.098526 FUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90987 GTEX-VJYA-0226-SM-4KL1Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.66436 proteasome accessory complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.348346 DOK DepMap CRISPR Gene Dependency 1.0 7.20724 PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.80812 BRD-K84054400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.98296 modulator GeneRIF Biological Term Annotations 1.0 null negative regulation of ossification GO Biological Process Annotations 2015 1.0 null BRD-K63900355 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04236 GTEX-RWS6-0326-SM-2XCAP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889858 Androgen-Insensitivity Syndrome DisGeNET Gene-Disease Associations 1.0 null GSE232631_4_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97212 serotonin metabolic process GO Biological Process Annotations 2025 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.941207 LX1031 DGIdb Drug Targets 2026 1.0 3.30825 rs1386494 GeneRIF Biological Term Annotations 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15313 arginine Phosphosite Textmining Biological Term Annotations 1.0 null Vermiform appendix TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.976 GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869685 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.9069 root TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071905 DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45734 BRD-K33637419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17314 globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.414293 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840065 Blastema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.053 liver_a HPA Tissue Sample Gene Expression Profiles -1.0 -1.8509 UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6385 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13872 bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25858 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08162 intermediate filament cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.329837 physical GeneRIF Biological Term Annotations 1.0 null tail TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.150991 pathogenesis GeneRIF Biological Term Annotations 1.0 null Opiate Addiction DisGeNET Gene-Disease Associations 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null bone marrow cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.115714 nonresponding GeneRIF Biological Term Annotations 1.0 null primary amino compound biosynthetic process GO Biological Process Annotations 2025 1.0 null different GeneRIF Biological Term Annotations 1.0 null TDGF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65078 Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null Premenstrual Dysphoric Disorder DisGeNET Gene-Disease Associations 1.0 null Cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.323 BRD-K06355852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38045 BRD-K11113009 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06304 schizophrenia; bipolar disorder; affective disorder GAD Gene-Disease Associations 1.0 null suicide GeneRIF Biological Term Annotations 1.0 null MRPS34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54552 Interstitial cell of Cajal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 CRCGN015_MCF10A.TP53.M_24H:E07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.4055 cessation GeneRIF Biological Term Annotations 1.0 null BRD-K95822658 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3513 GTEX-PLZ6-0926-SM-3P5ZQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.992675 biological_process GO Biological Process Annotations 2015 1.0 null Sexual dysfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 chicken GeneRIF Biological Term Annotations 1.0 null CIAO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76395 progressive supranuclear palsy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.229024 Intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.614 SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.44419 BRD-K55144248 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1529 P-815 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.85712 pre-eclampsia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.285 Primary somatosensory area, upper limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73362 mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Pancreatic islet cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.112 GTEX-OHPL-0426-SM-3TW8X GTEx Tissue Sample Gene Expression Profiles 1.0 1.99285 parietal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.616586 process GeneRIF Biological Term Annotations 1.0 null subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51151 GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null dexamethasone_mus musculus_gpl339_gds2314 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF676 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38427 variable GeneRIF Biological Term Annotations 1.0 null TENC1 Pathway Commons Protein-Protein Interactions 1.0 null Completed Suicide DisGeNET Gene-Phenotype Associations 1.0 null BRD-K93203589 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.9538 GTEX-T5JW-0326-SM-4DM6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.951121 TMEM134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30439 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35172 inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.342006 Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.871 Bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.165 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94528 GSTK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57886 IDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01472 BRD-K97943226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19673 ZZEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0377 criminal GeneRIF Biological Term Annotations 1.0 null Hyperostosis DisGeNET Gene-Disease Associations 1.0 null CTV1DM DepMap CRISPR Gene Dependency 1.0 3.23975 TCEAL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55393 Spermatheca TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.318 GSE173873_1_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null ABRA Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-2110 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Recurrence HuGE Navigator Gene-Phenotype Associations 1.0 null SIRT1_KO_GDS4895_410_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Constipation DisGeNET Gene-Phenotype Associations 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.18537 Prostate adenocarcinoma_PRAD_TCGA-G9-6363-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TPT-004 DGIdb Drug Targets 2026 1.0 1.65412 Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47726 indicator GeneRIF Biological Term Annotations 1.0 null regulation of fat cell differentiation GO Biological Process Annotations 2015 1.0 null GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35853 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.590839 MCTS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80843 BRD-K94751306 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23902 Anxiety DisGeNET Gene-Disease Associations 1.0 null Thrombocytopenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.053 voltage-gated calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.033 purine-pyrimidine metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.438658 Depression DisGeNET Gene-Phenotype Associations 1.0 null immunoreactivity GeneRIF Biological Term Annotations 1.0 null Thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.559 immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.724907 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247079 Agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 CA11 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00468019 truncated GeneRIF Biological Term Annotations 1.0 null GTEX-OXRL-1826-SM-2YUMV GTEx Tissue Sample Gene Expression Profiles 1.0 1.00802 Perturb_8940_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41909 mothers GeneRIF Biological Term Annotations 1.0 null SUCLG1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-REY6-0626-SM-2TF4G GTEx Tissue Sample Gene Expression Profiles 1.0 0.928716 ties GeneRIF Biological Term Annotations 1.0 null Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47821 BRD-K19168437 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43356 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.48786 GTEX-Q2AH-0008-SM-48U2J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8526 SCML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50818 UBAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75721 Biogenic Amine Synthesis(Homo sapiens) WikiPathways Pathways 2014 1.0 null MAP1A Pathway Commons Protein-Protein Interactions 1.0 null SMTN Pathway Commons Protein-Protein Interactions 1.0 null Rheumatoid arthritis disease specific fibroblast-like synoviocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.918 variation GeneRIF Biological Term Annotations 1.0 null Nutritional deficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 cone-rod dystrophy 16 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.23 OSBPL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00918 YWHAH Hub Proteins Protein-Protein Interactions 1.0 null platelet degranulation GO Biological Process Annotations 2023 1.0 null GSS CCLE Cell Line Gene CNV Profiles 1.0 1.83382 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null C20orf57 Pathway Commons Protein-Protein Interactions 1.0 null TEX2 Pathway Commons Protein-Protein Interactions 1.0 null Brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.522 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25151 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.01723 Metabolism of amine-derived hormones Reactome Pathways 2024 1.0 null UTP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11912 impulse control disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.188632 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98576 attempters GeneRIF Biological Term Annotations 1.0 null Squamous cell carcinoma_Lung Tissue_GSE1987 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 0.397483 GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853135 CREB3L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97542 Alcohol dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.016 Forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.56 Ventral nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.15 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amrinone-2724 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18448 Nape TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656 affective GeneRIF Biological Term Annotations 1.0 null NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null CASTOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17335 non-Hodgkin lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.39554 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981449 calpha GeneRIF Biological Term Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCKDK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04994 SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67099 medullary thyroid carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195187 therapeutic GeneRIF Biological Term Annotations 1.0 null Childhood Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null Carcinoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.653 GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null vary GeneRIF Biological Term Annotations 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.60944 NPR1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S3XE-0326-SM-4AD6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.56822 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.08792 Small intestine epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.061 GTEX-P44H-0526-SM-2XCF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00521 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.74081 time GeneRIF Biological Term Annotations 1.0 null periventricular stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3153 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73385 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.922434 GTEX-WFG7-1726-SM-4LVME GTEx Tissue Sample Gene Expression Profiles 1.0 0.876494 MYO1D Pathway Commons Protein-Protein Interactions 1.0 null pulmonary artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.565232 GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8493 BRD-K49042040 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.48598 regulation of cellular process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null CNOT11 Pathway Commons Protein-Protein Interactions 1.0 null victims GeneRIF Biological Term Annotations 1.0 null RFX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.941 Cerebral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.576 HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.795352 PGAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7623 GTF3C4 Pathway Commons Protein-Protein Interactions 1.0 null th2 GeneRIF Biological Term Annotations 1.0 null Presynapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.146 microtubule cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.228819 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03779 BRD-K87712055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89845 pah GeneRIF Biological Term Annotations 1.0 null t52-hippocampus_male_4w MoTrPAC Rat Endurance Exercise Training -1.0 -3.21352 synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.708465 PRXL2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39772 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.851992 circumference GeneRIF Biological Term Annotations 1.0 null decreased serotonin level MGI Mouse Phenotype Associations 2023 1.0 null organic hydroxy compound biosynthetic process GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10054 personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.42279 carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BRD-K61973443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17481 Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null unclear GeneRIF Biological Term Annotations 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null Subesophageal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.784 Colonic epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.572 autism GAD Gene-Disease Associations 1.0 null tryptophan metabolism KEGG Pathways 1.0 null PK59 CCLE Cell Line Gene Expression Profiles 1.0 1.46537 ZNF615 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03883 periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.14355 IL16 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.575 XPNPEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79944 PMC7559772__F2 PFOCR Pathway Figure Associations 2023 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mt2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.486 Gravid adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.76 ZNF816 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22715 NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NAIP Pathway Commons Protein-Protein Interactions 1.0 null Multiple Sclerosis HuGE Navigator Gene-Phenotype Associations 1.0 null NCIH1436 CCLE Cell Line Gene Expression Profiles -1.0 -2.23379 dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01243 PFSK1 DepMap CRISPR Gene Dependency 1.0 3.58824 TCCPAN2 CCLE Cell Line Gene Expression Profiles -1.0 -1.98661 Circadian rhythm genes WikiPathways Pathways 2024 1.0 null Egg white TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.668 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.592845 markers GeneRIF Biological Term Annotations 1.0 null leukopenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.100247 response to immobilization stress GO Biological Process Annotations 2015 1.0 null Biogenic amine synthesis WikiPathways Pathways 2024 1.0 null PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPJH-0726-SM-4IHJW GTEx Tissue Sample Gene Expression Profiles 1.0 0.909663 posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868154 GTEX-T8EM-0426-SM-4DM7E GTEx Tissue Sample Gene Expression Profiles 1.0 1.377 superficial stratum of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05226 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5055 plastid-encoded plastid RNA polymerase complex A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.768 CRCGN015_HEPG2_48H:L19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.71855 Autonomic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.305 MAST4 Pathway Commons Protein-Protein Interactions 1.0 null aminocaproic acid-3122 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null Median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.91 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.616 macrocytic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.328105 GTEX-QVJO-0526-SM-447CE GTEx Tissue Sample Gene Expression Profiles 1.0 1.90773 MSTO211H CCLE Cell Line Gene Expression Profiles -1.0 -1.49265 Autoimmune disease of the nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.73 INPP4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35425 HOXB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35128 PMC7933006__F2 PFOCR Pathway Figure Associations 2024 1.0 null 6-fluorotryptophan Guide to Pharmacology Chemical Ligands of Receptors 1.0 null NUP98 Pathway Commons Protein-Protein Interactions 1.0 null STX1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34673 RB1_KD_GSE50532_641_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K43729445 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96536 Epithelial cell_Epithelium_Human CellMarker Gene-Cell Type Associations 1.0 null TELOTRISTAT ETIPRATE DGIdb Drug Targets 2026 1.0 1.65412 supporting GeneRIF Biological Term Annotations 1.0 null GSE60217_1_v_7_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null Autoimmune polyendocrine syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.354 GTEX-RWS6-0526-SM-4GIAJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.386 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.839829 GSE208435_0_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null KMRC3 CCLE Cell Line Gene Expression Profiles -1.0 -1.77518 PER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52683 Chromosomal deletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 GSE148262,GSE150691_3_v_2_hdlbp_human RummaGEO Gene Perturbation Signatures 1.0 null Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9362 GSE150669_0_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null Diphtheria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.111 Cecum cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.677 BRD-K98117883 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05264 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBXIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02043 osteoporosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.364824 GSE232631_5_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.17417 RFX7 Pathway Commons Protein-Protein Interactions 1.0 null TNKS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50383 orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34281 idiopathic GeneRIF Biological Term Annotations 1.0 null GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Adrenal gland hyperfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.077 stomach_3a HPA Tissue Sample Gene Expression Profiles 1.0 1.87505 BRD-K69093885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0562 Monocytic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.827 Folate biosynthesis KEGG Pathways 2026 1.0 null substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.19704 Lupus erythematosus DISEASES Text-mining 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Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57861 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.594 GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833271 immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.43941 spin GeneRIF Biological Term Annotations 1.0 null BRD-K71194915 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01417 inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.565666 Bipolar Disorder_Lymphocyte_GSE7036 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.1601 tardive dyskinesia GAD Gene-Disease Associations 1.0 null Atherosclerosis CTD Gene-Disease Associations 1.0 1.05015 Sudden infant death syndrome SIDS susceptibility pathways WikiPathways Pathways 2024 1.0 null astroglial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232881 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.93833 bowel dysfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.99233 BRD-K43896262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05973 TMEM59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09076 SNRPF Pathway Commons Protein-Protein Interactions 1.0 null TRRAP Pathway Commons Protein-Protein Interactions 1.0 null Postcentral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.102 Thyroid dyshormonogenesis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.61 amygdaloid complex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22906 Signaling by Receptor Tyrosine Kinases Reactome Pathways 2024 1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3018 BRD-K47348275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19008 Gastroenteritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.117 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12236 BRD-K48764596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69009 BRD-K60484506 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34517 mammary gland alveolus development GO Biological Process Annotations 2015 1.0 null SERPINH1 Pathway Commons Protein-Protein Interactions 1.0 null DTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67075 Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC4271336-13041_2014_88_MOESM6_ESM.xlsx-Genes_in_GENE_CARD_MR_or_ID-Gene_Cards_MR_and_ID_genes_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null MOG-G-UVW COSMIC Cell Line Gene Mutation Profiles 1.0 null NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dat1 GeneRIF Biological Term Annotations 1.0 null HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null r10 part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13442 offspring GeneRIF Biological Term Annotations 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3192 Calprotectin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.237 PACSIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88195 LEUTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65762 GLTSCR1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K89089981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41307 Fungal infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.187 aggression GeneRIF Biological Term Annotations 1.0 null monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047316 CNTN5 Pathway Commons Protein-Protein Interactions 1.0 null TPP1 Pathway Commons Protein-Protein Interactions 1.0 null Colon sigmoideum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.31 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null movement disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.440538 epitopes GeneRIF Biological Term Annotations 1.0 null panic GeneRIF Biological Term Annotations 1.0 null SHI1 DepMap CRISPR Gene Dependency 1.0 2.61168 nearly GeneRIF Biological Term Annotations 1.0 null Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.842 hypersensitivity GeneRIF Biological Term Annotations 1.0 null GSE152937_6_v_5_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32927 JM1 CCLE Cell Line Gene Expression Profiles 1.0 1.64478 PMC6829839-13578_2019_352_MOESM5_ESM.xlsx-Table_5-SRG_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null TMEM39B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43601 Temporomandibular Joint Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null ZBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94666 Subfornical organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.55 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.49914 vitiligo DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.316092 cingulate gyrus, parietal part, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932781 abnormal respiratory system physiology MPO Gene-Phenotype Associations 1.0 null susceptibility GeneRIF Biological Term Annotations 1.0 null htr2a GeneRIF Biological Term Annotations 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39775 ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.466928 Colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.386 GTEX-UJMC-1326-SM-4IHLS GTEx Tissue Sample Gene Expression Profiles 1.0 0.957648 spastic cerebral palsy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.23945 Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovarian disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 adolescent GeneRIF Biological Term Annotations 1.0 null APOBEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3055 amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17526 BRD-K67626198 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05083 BRD-K14309706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00568 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043158 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.452 BRD-K01699883 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05603 Malaria DisGeNET Gene-Disease Associations 1.0 null nerve plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220831 Granular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09477 posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00668 protein-dna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.066807 response to stimulus GO Biological Process Annotations 2015 1.0 null TXN Pathway Commons Protein-Protein Interactions 1.0 null somatoform disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.623751 Persistent fetal circulation syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.63 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.945656 GSE173873_4_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bacteroid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.549 uvntr GeneRIF Biological Term Annotations 1.0 null Lateral ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.52 CBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74077 neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.977104 PLA2G1B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00520417 Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.255 GSE236262_0_v_3_trim28_mouse RummaGEO Gene Perturbation Signatures 1.0 null IFI27L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53452 Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gastrointestinal system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.218 Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null han GeneRIF Biological Term Annotations 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6561 DHX58 Pathway Commons Protein-Protein Interactions 1.0 null congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.278297 GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.07951 genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.360764 FASTKD1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QEG4-1226-SM-2S1P6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27677 GSE173873_8_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null KRT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87305 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83576 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null scoliosis GAD Gene-Disease Associations 1.0 null GTEX-PWCY-0926-SM-48TD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22969 GSE148066,GSE157787_5_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K39074860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03985 BRD-K89532826 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49478 TAFAZZIN LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00524235 GTEX-XBED-1526-SM-4AT5W GTEx Tissue Sample Gene Expression Profiles 1.0 0.85189 abnormal respiration MPO Gene-Phenotype Associations 1.0 null RASSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48746 general GeneRIF Biological Term Annotations 1.0 null ADAMTS20 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K37830990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40282 abnormal heart morphology MPO Gene-Phenotype Associations 1.0 null Enteroendocrine cell_Intestinal crypt_Mouse CellMarker Gene-Cell Type Associations 1.0 null PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null GSE118794_0_v_1_zmynd8_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.63651 Mast cell neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.253 schizoaffective disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.400453 Ischemic colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.386 PMC5836539-MSB-14-e7858-s004.xlsx-MITF_target_genes-MITF_transcriptional_target_genes1_MITF Rummagene Transcription Factor Associations 2026 1.0 null cerebral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31877 tryptophan 5-monooxygenase activity GO Molecular Function Annotations 2025 1.0 null RAPGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95265 hsa-miR-320a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-NPJ8-0426-SM-2HMK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03176 BRD-K11476310 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02192 MIB1 Pathway Commons Protein-Protein Interactions 1.0 null basis pedunculi cerebri TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.562441 CTR9 Pathway Commons Protein-Protein Interactions 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null camkii Phosphosite Textmining Biological Term Annotations 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79538 Parathyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.921 OSBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68622 HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAP3K7 Pathway Commons Protein-Protein Interactions 1.0 null GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PLEKHH1 Pathway Commons Protein-Protein Interactions 1.0 null cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.992814 GTEX-RTLS-0326-SM-2TF6A GTEx Tissue Sample Gene Expression Profiles 1.0 0.831865 SBNO2 Pathway Commons Protein-Protein Interactions 1.0 null CRCGN017_MCF10A.TP53.M_24H:J01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4514 PRPSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.4474 KRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40218 4a-Carbinolamine tetrahydrobiopterin HMDB Metabolites of Enzymes 1.0 null smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.873603 primary motor cortex (area M1, area 4)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1182 nterminally GeneRIF Biological Term Annotations 1.0 null DPM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86726 transmitted GeneRIF Biological Term Annotations 1.0 null Personality Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null Trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 MFE296 DepMap CRISPR Gene Dependency 1.0 5.99468 Atherosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 Attention Deficit Disorder DisGeNET Gene-Disease Associations 1.0 null epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052539 liminal part of alar isthmus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04238 MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.96198 GTEX-T6MO-1926-SM-32QOJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.23261 RAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30423 Attention Deficit Disorder with Hyperactivity HuGE Navigator Gene-Phenotype Associations 1.0 null Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.069 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.6601 MTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64004 HIST1H1A Pathway Commons Protein-Protein Interactions 1.0 null Brain - Putamen (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 0.399888 lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054946 ls1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 did GeneRIF Biological Term Annotations 1.0 null adolescents GeneRIF Biological Term Annotations 1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 generalized anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.538118 Labial gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.73 Oligospermia CTD Gene-Disease Associations 1.0 1.11843 pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.363393 organic acid metabolic process GO Biological Process Annotations 2015 1.0 null superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20274 RNF167 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47629 neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.41087 cellular metabolic process GO Biological Process Annotations 2015 1.0 null Allergic contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115 specifically GeneRIF Biological Term Annotations 1.0 null PRKCDBP Pathway Commons Protein-Protein Interactions 1.0 null Mammary epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.364 Endocrine pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.121 relationship GeneRIF Biological Term Annotations 1.0 null GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15362 Tcof1_KD_GDS998_155_mouse_neuroblastoma N1E-115 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null presence GeneRIF Biological Term Annotations 1.0 null Insulinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.162 KOPN8 CCLE Cell Line Gene Mutation Profiles 1.0 null Perturb_3340_KO_Cns4_SRP310440 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.35587 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.794181 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.7077 deviation GeneRIF Biological Term Annotations 1.0 null mediate GeneRIF Biological Term Annotations 1.0 null Dendritic spine neck COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.822 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.929363 Central Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null BRD-K96416345 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02352 maturity-onset diabetes of the young DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 A673 DepMap CRISPR Gene Dependency 1.0 2.87446 autoimmune disease of endocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.608494 linkage GeneRIF Biological Term Annotations 1.0 null GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.24945 inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04295 EIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2619 Neurodevelopmental disorder with eye movement abnormalities and ataxia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.581 promoter GeneRIF Biological Term Annotations 1.0 null HBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60802 MRPL14 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29501 OSC19 DepMap CRISPR Gene Dependency 1.0 6.31814 Collagenous colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 ZNF420 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4481 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.42774 Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.416 priming GeneRIF Biological Term Annotations 1.0 null PIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68974 confirm GeneRIF Biological Term Annotations 1.0 null mastocytoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.89562 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61579 Parietal trophoblast giant cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.685 PRMT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04765 axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.965512 central gray substance of midbrain, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.883014 Autism DisGeNET Gene-Disease Associations 1.0 null japanese GeneRIF Biological Term Annotations 1.0 null Tryptophan 5-monooxygenase InterPro Predicted Protein Domain Annotations 1.0 null PMC9052432-szac008_suppl_supplementary_table_s4.docx-2-SOX2_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null traumatic GeneRIF Biological Term Annotations 1.0 null organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048609 BRD-K28923989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00466 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.08476 subject GeneRIF Biological Term Annotations 1.0 null tympanum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.252261 NMCG1 CCLE Cell Line Gene Expression Profiles 1.0 1.55283 Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33367 modulation GeneRIF Biological Term Annotations 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10228 schizophrenic GeneRIF Biological Term Annotations 1.0 null reported GeneRIF Biological Term Annotations 1.0 null Degenerative Polyarthritis DisGeNET Gene-Disease Associations 1.0 null TMEM8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42162 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.572 MDA-MB-330 COSMIC Cell Line Gene Mutation Profiles 1.0 null controls GeneRIF Biological Term Annotations 1.0 null level GeneRIF Biological Term Annotations 1.0 null L-type voltage-gated calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.032 basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.89409 FAM171B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38803 blood vessel endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.261284 Dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.87 GTEX-UJHI-0226-SM-4IHJL GTEx Tissue Sample Gene Expression Profiles 1.0 1.712 Sympathetic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.434 mdd GeneRIF Biological Term Annotations 1.0 null BRD-K65602491 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30468 Parasympathetic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.239 caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274394 BRD-K17675814 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02947 Temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.256 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10056 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.29764 circadian rhythm GO Biological Process Annotations 2015 1.0 null layer 5 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23738 plexiform layer of TuPal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02173 Thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.510418 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75492 C1orf52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51266 TTLL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86828 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-R55G-0008-SM-48FEX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.876649 disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.626888 avoidance GeneRIF Biological Term Annotations 1.0 null Umbilical artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.889 Large_Intestine-intestinal enteroendocrine cell Tabula Sapiens Gene-Cell Associations 1.0 5.14344 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.73214 making GeneRIF Biological Term Annotations 1.0 null GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05349 SEC11C Pathway Commons Protein-Protein Interactions 1.0 null BRD-K00191683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46728 regulation of ossification GO Biological Process Annotations 2015 1.0 null epithalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CRCGN015_HEPG2_48H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.46735 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20399 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.776909 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07019 nicotine dependence; smoking initiation GAD Gene-Disease Associations 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.34229 major depressive disorder GAD Gene-Disease Associations 1.0 null BRD-K23342427 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34494 CMTM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01934 cardiovascular GAD High Level Gene-Disease Associations 1.0 0.293278 ITPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22684 BRD-K90255725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17466 KIF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.234 GTEX-NPJ8-0011-R4a-SM-2HML3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84302 APP Pathway Commons Protein-Protein Interactions 1.0 null pituitary GeneRIF Biological Term Annotations 1.0 null CREB3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70125 ATP5MC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58589 corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.8672 his452tyr GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ8-2226-SM-3TW8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09667 NSUN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02265 Nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.855 Presynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.734 abnormal heartbeat MPO Gene-Phenotype Associations 1.0 null TFB2M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.79776 BRD-K47098496 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13802 APUD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.5 ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839703 thp1 HPA Cell Line Gene Expression Profiles 1.0 0.941442 GSE184210_0_v_1_glucagon_mouse RummaGEO Drug Perturbation Signatures -1.0 null EHHADH Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null psychosis GAD Gene-Disease Associations 1.0 null increased heart rate MGI Mouse Phenotype Associations 2023 1.0 null abnormal breathing pattern MPO Gene-Phenotype Associations 1.0 null BRD-K49847771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2084 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.1559 Dermal dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.879 Asthma, allergic_Bronchial epithelium_GSE3004 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.07953 B4GALT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69238 CITALOPRAM DGIdb Drug Targets 2026 1.0 0.435296 maoa GeneRIF Biological Term Annotations 1.0 null Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.9643 CCNJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31669 GTEX-OIZI-0526-SM-2XCEG GTEx Tissue Sample Gene Expression Profiles 1.0 1.12736 choroid plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274045 BRD-K65875972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30713 BRD-K11804865 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.2151 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.975 glia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.332661 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0041 Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.517 Chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 schizophrenia GeneRIF Biological Term Annotations 1.0 null Mammary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.405 COLO-824 COSMIC Cell Line Gene Mutation Profiles 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Liver Diseases CTD Gene-Disease Associations 1.0 1.23424 Perinatal necrotizing enterocolitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 bile duct cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.082036 finnish GeneRIF Biological Term Annotations 1.0 null NET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05836 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84297 PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null borderline personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.3952 plastid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.229176 mood GeneRIF Biological Term Annotations 1.0 null PLEKHB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48207 vulnerability GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Archenteron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -1.9496 AHNAK2 Pathway Commons Protein-Protein Interactions 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_8942_KO_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Dopaminergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.026 Muscular coat TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.41 Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57175 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18834 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08041 BHLHE40 ENCODE Transcription Factor Targets 1.0 null Central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.77 BRD-K48541282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00961 posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838636 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4999 Serotonin and melatonin biosynthesis Reactome Pathways 2024 1.0 null Integral component of synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.65 superficial layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61735 stress GeneRIF Biological Term Annotations 1.0 null remission GeneRIF Biological Term Annotations 1.0 null GTEX-S4UY-0826-SM-4AD4Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.920232 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837628 Intestinal wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.611 differed GeneRIF Biological Term Annotations 1.0 null ChIP_YY1_21170310 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ITGAL Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5273-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eating GeneRIF Biological Term Annotations 1.0 null Rheumatic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0751 Tetrahydrobiopterin DrugBank Drug Targets 1.0 null HT COSMIC Cell Line Gene Mutation Profiles 1.0 null Fatigue DisGeNET Gene-Phenotype Associations 1.0 null BRD-K28522188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10617 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.105 ZCCHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00722 differentially GeneRIF Biological Term Annotations 1.0 null Midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.331 Pregnancy Complications HuGE Navigator Gene-Phenotype Associations 1.0 null UBA1 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44685 BRD-K21196859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37325 Antisocial Behavior DisGeNET Gene-Phenotype Associations 1.0 null Organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.29 forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ibs GeneRIF Biological Term Annotations 1.0 null reports GeneRIF Biological Term Annotations 1.0 null GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10815 Carcinoma Of Bladder DisGeNET Gene-Disease Associations 1.0 null Tumor Progression DisGeNET Gene-Phenotype Associations 1.0 null homeostasis/metabolism phenotype MPO Gene-Phenotype Associations 1.0 null Ovarian Failure, Premature HuGE Navigator Gene-Phenotype Associations 1.0 null LS123 DepMap CRISPR Gene Dependency 1.0 5.19438 borderline GeneRIF Biological Term Annotations 1.0 null Pellagra DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.096 Type 2 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.066 hydroxylase Phosphosite Textmining Biological Term Annotations 1.0 null chemdependency GAD High Level Gene-Disease Associations 1.0 0.326393 Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0862 Anteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29468 CRCGN015_HEPG2_48H:P06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.78449 MIOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54914 Substance-Related Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00933 GSE242167_1_v_2_cd40_mouse RummaGEO Gene Perturbation Signatures 1.0 null Panic Disorder DisGeNET Gene-Disease Associations 1.0 null Juvenile rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 LRP1B Pathway Commons Protein-Protein Interactions 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.191 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.501 PRICKLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62038 mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.225229 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00933 organic hydroxy compound metabolic process GO Biological Process Annotations 2015 1.0 null Chromosome Aberrations CTD Gene-Disease Associations 1.0 1.39924 Uterus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.998263 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null domains GeneRIF Biological Term Annotations 1.0 null MYORG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74921 duality GeneRIF Biological Term Annotations 1.0 null cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.826942 serine-tRNA ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.983 GSE148066,GSE157787_9_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Phobic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.502 Perturb_8953_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Glucose homeostasis traits GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.61549 GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles 1.0 1.0531 Mesenteric lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.235 BRD-K44078665 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76892 Osteoarthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 BRD-K82781769 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04989 Perturb_4866_KO_HES1_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 STK38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97623 ring GeneRIF Biological Term Annotations 1.0 null CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.835352 HOXA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23977 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.186355 GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.04346 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07041 agoraphobia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.248905 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 0.925646 AKT1_knockout_212_GSE39699 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.45363 BPTF Pathway Commons Protein-Protein Interactions 1.0 null GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null tested GeneRIF Biological Term Annotations 1.0 null Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.645 FLOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06219 m86 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.523 CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56081 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71896 pituitary GTEx Tissue Gene Expression Profiles 1.0 0.967942 DDX25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74553 autoimmune polyendocrine syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.03072 epididymis HPA Tissue Protein Expression Profiles -1.0 -0.873603 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910446 Steatohepatitis DisGeNET Gene-Disease Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K90460185 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21537 Glutamatergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.246 PMC4951461__F2 PFOCR Pathway Figure Associations 2024 1.0 null SHSYSY+RA BioGPS Cell Line Gene Expression Profiles -1.0 -1.11619 Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null separated GeneRIF Biological Term Annotations 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.35676 ELMSAN1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K34377350 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05343 Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.35463 Sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.118 BRD-K45503385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.38612 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW954 DepMap CRISPR Gene Dependency 1.0 2.97264 PFKFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30655 FBXO41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03853 hepg2 HPA Cell Line Gene Expression Profiles 1.0 1.23657 Perturb_1427_OE_Mir335_ERP106848 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.46734 axon part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.957352 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SLC8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5781 PLAT LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00531798 arterial smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.581618 SLC36A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46821 CYBA Pathway Commons Protein-Protein Interactions 1.0 null BRD-K10189430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42485 GTEX-Q2AH-0326-SM-48U1K GTEx Tissue Sample Gene Expression Profiles 1.0 1.08378 BRD-K64860662 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.00033 superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22193 sert GeneRIF Biological Term Annotations 1.0 null BRD-K41135617 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08212 Parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.506 Retinoblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 Thrombosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.338 carry GeneRIF Biological Term Annotations 1.0 null support GeneRIF Biological Term Annotations 1.0 null colonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.856497 imidazoleglycerol-phosphate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.5 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53299 Mucosal mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.676 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.812 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.728563 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO Molecular Function Annotations 2023 1.0 null premenstrual tension DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.550522 Gastric gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.408 PITX2 Pathway Commons Protein-Protein Interactions 1.0 null Cholinergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.986 Hyperprolactinemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 Heroin Dependence DisGeNET Gene-Disease Associations 1.0 null DPP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6784 BRD-K44916315 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00427 Nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.329 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22075 GSE96641_3_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null anteroventral part of alar thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3512 GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.842833 BRD-K24308170 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.09245 metronidazole-4023 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056328 neither GeneRIF Biological Term Annotations 1.0 null Diseases in Twins HuGE Navigator Gene-Phenotype Associations 1.0 null PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55G-0626-SM-48FDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.26865 CRCGN015_HEPG2_48H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.30129 FXR MotifMap Predicted Transcription Factor Targets 1.0 null BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2971 FGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57037 heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null MOTN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52518 Curcumin CTD Gene-Chemical Interactions 1.0 null NMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54015 Biogenic Amine Synthesis(Mus musculus) WikiPathways Pathways 2014 1.0 null superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69111 Protocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.088 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.739 case GeneRIF Biological Term Annotations 1.0 null PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPJH-0626-SM-4IHJN GTEx Tissue Sample Gene Expression Profiles 1.0 0.974967 BRD-K74705119 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46136 bone resorption disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.35892 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.248554 simultaneously GeneRIF Biological Term Annotations 1.0 null BRD-K63887881 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.99099 GSE188870,GSE188871_0_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K35945596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10796 LCLC97TM1 DepMap CRISPR Gene Dependency 1.0 5.24312 Arteriosclerosis DisGeNET Gene-Disease Associations 1.0 null CSKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52496 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07807 MUC5AC Pathway Commons Protein-Protein Interactions 1.0 null cas1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.522 BRD-K62983405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47396 ZNF234 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20234 Lewy neurite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.665 Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.34 BeWo cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.675 BRD-K47650707 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24554 C2CD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54619 GTEX-XUJ4-0326-SM-4BOP9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73057 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PLOD2 Pathway Commons Protein-Protein Interactions 1.0 null Drug dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.5 UBXN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54147 Gastric antrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.481 been GeneRIF Biological Term Annotations 1.0 null Abomasum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.562 peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.279659 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.872 stability GeneRIF Biological Term Annotations 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06266 Bicellular tight junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.281 GTEX-O5YV-0006-SM-2I5GX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87444 APEH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41587 organonitrogen compound biosynthetic process GO Biological Process Annotations 2015 1.0 null Autoimmune disease of endocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388 GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.967753 CCDC88A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02362 Interstitial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.466 KPNA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34635 impulsive behavior GAD Gene-Disease Associations 1.0 null 496100417_HIP_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15383 BRD-K80568112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9189 Fibrosis, Liver DisGeNET Gene-Disease Associations 1.0 null CRCGN009_HEPG2_24H:A18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.252 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.31331 Anorexia nervosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.382 E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3552 MRPL14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26972 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.74789 abnormal homeostasis MPO Gene-Phenotype Associations 1.0 null prefrontal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.05853 Perturb_14552_KO_Abcc8_ERP018163 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 somatic anxiety GAD Gene-Disease Associations 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.851304 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897001 CORL51 CCLE Cell Line Gene Expression Profiles -1.0 -1.60171 GATA1 ChEA Transcription Factor Targets 1.0 null Perturb_14667_KO_Sirt3_SRP277814 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.076924 thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.160948 PMC4951461__F2 PFOCR Pathway Figure Associations 2023 1.0 null t52-hippocampus_male_1w MoTrPAC Rat Endurance Exercise Training -1.0 -3.52539 BRD-K74015591 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2228 EGFL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26567 selfstimulatory GeneRIF Biological Term Annotations 1.0 null TC-YIK GDSC Cell Line Gene Expression Profiles 1.0 1.93356 SNUC2A CCLE Cell Line Gene Mutation Profiles 1.0 null CERS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49463 Collagen type XI trimer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.798 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC12A5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00595038 GATA1_G1E-ER4_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07507 PHF6 Pathway Commons Protein-Protein Interactions 1.0 null Bone resorption disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.847 GSE148692,GSE148695_7_v_6_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null UQCRFS1 Pathway Commons Protein-Protein Interactions 1.0 null Enteroendocrine cell_Stomach_Human CellMarker Gene-Cell Type Associations 1.0 null Colon ascendens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.005 KIAA1586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68564 Intestinal pseudo-obstruction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.94112 Pluteus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.85 PRDM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50306 PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-MXD1_MXD1 Rummagene Transcription Factor Associations 2026 1.0 null ADNP Pathway Commons Protein-Protein Interactions 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01238 DARS1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00708734 ITPR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50531 heroid GeneRIF Biological Term Annotations 1.0 null GSE119978,GSE180930_2_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.26127 preoptic area TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.801876 bipolar GeneRIF Biological Term Annotations 1.0 null PCDHGC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49595 RRP1B Pathway Commons Protein-Protein Interactions 1.0 null Impulse control disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.354 clinical GeneRIF Biological Term Annotations 1.0 null NCIH358 CCLE Cell Line Gene Expression Profiles -1.0 -2.36798 GTEX-OHPM-0726-SM-3LK7A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38415 GSE249714_0_v_1_anxa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null rectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.394953 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836417 PAPOLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59217 tryptophan 5-monooxygenase activity GO Molecular Function Annotations 2015 1.0 null ATP6V1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16424 BRD-K37803976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00456 MAP3K1 Pathway Commons Protein-Protein Interactions 1.0 null Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 BRD-K02927989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.93717 ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.75787 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.756191 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.94736 mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07154 Villous trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.771 Gall bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.191 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072428 GTEX-PLZ5-0626-SM-2I5F8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914908 Immune System Diseases CTD Gene-Disease Associations 1.0 1.22145 lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84297 Chronic mucocutaneous candidiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60459 Personality Assessment HuGE Navigator Gene-Phenotype Associations 1.0 null METTL21A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2918 GTEX-O5YW-0426-SM-3MJHJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.04495 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.617133 SRC_overexpression_276_GSE37428 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.5239 BRD-K67998155 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31651 hela HPA Cell Line Gene Expression Profiles -1.0 -1.45501 DNPEP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38313 Umbilical vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.933 GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 0.915729 bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15852 dysphoric GeneRIF Biological Term Annotations 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48394 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245175 cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null PMC9515494__F8 PFOCR Pathway Figure Associations 2024 1.0 null scores GeneRIF Biological Term Annotations 1.0 null NGDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13877 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03537 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 GTEX-QVUS-0426-SM-48FE3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13945 PMC4417587__F1 PFOCR Pathway Figure Associations 2024 1.0 null heroin dependence GAD Gene-Disease Associations 1.0 null 7,8-Dihydro-L-Biopterin DrugBank Drug Targets 1.0 null MKL1 Pathway Commons Protein-Protein Interactions 1.0 null substantia nigra TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.13324 PMC7922079__F4 PFOCR Pathway Figure Associations 2024 1.0 null Major Depressive Disorder DisGeNET Gene-Disease Associations 1.0 null TCEAL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03628 adolescent-onset antisocial behavior GAD Gene-Disease Associations 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10228 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2659 Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phenylketonuria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.986007 Gastric fundus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.877 5-Hydroxytryptamine biosynthesis PANTHER Pathways 1.0 null TGIF2LY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75684 PRKCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73376 Irritable bowel syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.745 GTEX-PLZ6-0326-SM-3P61J GTEx Tissue Sample Gene Expression Profiles 1.0 2.10819 MFSD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9754 TMEM35A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47544 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A817-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17247 H1-7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99308 RNF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37225 Social phobia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.963542 NOM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37864 PMC5918594__F4 PFOCR Pathway Figure Associations 2024 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09359 acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.35082 curve GeneRIF Biological Term Annotations 1.0 null suggests GeneRIF Biological Term Annotations 1.0 null COX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85333 LN-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 ODAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86476 casecontrol GeneRIF Biological Term Annotations 1.0 null synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.732422 ACBD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73878 TMEM254 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91999 Extrinsic asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.022 Perturb_7989_KO_Dnmt3a_ERP107953 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.40001 TMEM14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85943 FOSL2 Pathway Commons Protein-Protein Interactions 1.0 null DUS4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59294 TADA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83335 BRD-K05841284 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23423 amygdala GeneRIF Biological Term Annotations 1.0 null GTEX-PSDG-0526-SM-2S1OH GTEx Tissue Sample Gene Expression Profiles 1.0 0.853398 BH4-deficient hyperphenylalaninemia A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.434 Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04722 CALD1 Pathway Commons Protein-Protein Interactions 1.0 null Nuclear Events (kinase and transcription factor activation) Reactome Pathways 2024 1.0 null POLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59349 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Chromosome Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null Neonate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.432 MUC3A Pathway Commons Protein-Protein Interactions 1.0 null Diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.441 GTEX-OHPL-3026-SM-3MJGS GTEx Tissue Sample Gene Expression Profiles 1.0 1.30976 primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34281 their GeneRIF Biological Term Annotations 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.6561 PDCD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71534 GAP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78409 Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 ZNF738 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.74262 leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056109 chordoid glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.532314 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22001 CFLAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26602 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.266203 dentate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.336336 asphyxia neonatorum DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.74883 BRD-K39709957 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2765 YWHAZ Pathway Commons Protein-Protein Interactions 1.0 null GIGYF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09578 Dorsal striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.1 GTEX-S32W-1926-SM-4AD63 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26019 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04455 Psychomotor Agitation HuGE Navigator Gene-Phenotype Associations 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.84824 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056314 ILDR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00526706 PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1 Rummagene Transcription Factor Associations 2026 1.0 null Brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.741 Neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.719 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33318 ZBTB18 Pathway Commons Protein-Protein Interactions 1.0 null mRNA_MYOD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Intestinal obstruction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 dms454 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.983 RHOQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70372 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.957722 Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.617 Tetrachlorodibenzodioxin CTD Gene-Chemical Interactions 1.0 null Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.1465 good GeneRIF Biological Term Annotations 1.0 null frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.51855 BRD-K85813125 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52434 Tooth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 Heterotrimeric G-protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.96 GTEX-OOBJ-0326-SM-33HBO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909516 BRD-K53224741 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10172 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.20447 GSE133691_2_v_0_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null SLC2A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9788 Disease Models, Animal HuGE Navigator Gene-Phenotype Associations 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855298 tph2 GeneRIF Biological Term Annotations 1.0 null RNASEH2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11713 bl-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224645 YBEY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6745 Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.57 attempt GeneRIF Biological Term Annotations 1.0 null BRD-K50330857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0086 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB11FIP5 Pathway Commons Protein-Protein Interactions 1.0 null increased heart rate MPO Gene-Phenotype Associations 1.0 null BRD-K78816149 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03304 PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF Rummagene Transcription Factor Associations 2026 1.0 null Colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.352 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30039 PXR (PXR:RXR) MotifMap Predicted Transcription Factor Targets 1.0 null Synaptic cleft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.128 Serotonergic synapse KEGG Pathways 2026 1.0 null BRD-K31503053 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17166 Ulcerative colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.066 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25008 Somatoform disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.491 dysplasias GeneRIF Biological Term Annotations 1.0 null pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.15384 BRD-K49005954 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.51204 behavior/neurological phenotype MPO Gene-Phenotype Associations 1.0 null GTEX-XMD1-0011-R10A-SM-4AT4A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960638 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19867 learning disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.300173 C1orf109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20626 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.527569 alcohol dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.01849 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24922 musical aptitude GAD Gene-Disease Associations 1.0 null duodenal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.604904 ventral nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289226 RING1B-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.788033 Systemic mycosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.219 GTEX-Q2AG-0926-SM-48U1Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.94192 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.46826 ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17508 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00424 Enteroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.494 PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null report GeneRIF Biological Term Annotations 1.0 null mantle zone of IC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13442 Brain Lower Grade Glioma_LGG_TCGA-FG-6689-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.924623 sudden infant death syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2495 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19995 RELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32824 multiple system atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.03704 BRD-K29903249 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.92541 GSE229973_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.915574 BRD-K96968070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10106 SETX Pathway Commons Protein-Protein Interactions 1.0 null COLO684 DepMap CRISPR Gene Dependency 1.0 4.21178 GSE143955_1_v_0_ripk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00499 Tripartite attachment complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.668 CENPJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62373 parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.94577 involvement GeneRIF Biological Term Annotations 1.0 null BRD-K42091424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15097 CRCGN011_HEPG2_24H:F03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.123 vagina HPA Tissue Protein Expression Profiles -1.0 -0.873603 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944065 KLF10 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3617 Decision Making HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Pyloric region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.548 chromosome GeneRIF Biological Term Annotations 1.0 null inversely GeneRIF Biological Term Annotations 1.0 null 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.51048 SNU-C4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.875 GTF2IRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19887 larynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.100465 CCIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85855 ALG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1806 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0403 alcoholism GAD Gene-Disease Associations 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.768197 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048819 Microscopic colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.915 VPS25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90708 Trypanosomiasis DisGeNET Gene-Disease Associations 1.0 null GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19166 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3191 BRD-K46703028 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88524 TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.27205 UBA52 Pathway Commons Protein-Protein Interactions 1.0 null LHX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03187 inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062652 taiwan GeneRIF Biological Term Annotations 1.0 null regulated exocytosis GO Biological Process Annotations 2025 1.0 null GSE173873_8_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null syndromerelated GeneRIF Biological Term Annotations 1.0 null BRD-K87167435 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67213 ERRFI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34785 disorders GeneRIF Biological Term Annotations 1.0 null mood disorder GAD Gene-Disease Associations 1.0 null GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946719 PMC3437946__F8 PFOCR Pathway Figure Associations 2023 1.0 null BRD-K76175734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.93723 Diverticulitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 GTEX-RWSA-0526-SM-2XCBC GTEx Tissue Sample Gene Expression Profiles 1.0 0.881989 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NHLH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48031 TMEM109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36795 Chemical colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.076 tobacco use disorder GAD Gene-Disease Associations 1.0 null external cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18997 Serotonin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.879 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.7859 orbital frontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868025 Dyspepsia DisGeNET Gene-Phenotype Associations 1.0 null ZHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77541 MCAS COSMIC Cell Line Gene Mutation Profiles 1.0 null link GeneRIF Biological Term Annotations 1.0 null BRD-K44260904 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.03315 constipation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.99908 Transmembrane transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.175 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null psychosis schizophrenia GAD Gene-Disease Associations 1.0 null PMC7922079__F4 PFOCR Pathway Figure Associations 2023 1.0 null GATA1-19941827-MEL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.48047 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null Idiopathic scoliosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.542 alzheimer's disease; aggressive behavior GAD Gene-Disease Associations 1.0 null ZNF781 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87941 BRD-K78315404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.23673 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.0 RBM10 Pathway Commons Protein-Protein Interactions 1.0 null epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055515 ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.057399 Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84266 ECC10 CCLE Cell Line Gene Expression Profiles 1.0 2.24638 hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.673917 taiwanese GeneRIF Biological Term Annotations 1.0 null dyspepsia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.390769 Primary hyperaldosteronism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 GTEX-OOBK-0425-SM-3LK5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.43321 RHOXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87233 hypothalamicpituitaryadrenal GeneRIF Biological Term Annotations 1.0 null Allergic asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 result GeneRIF Biological Term Annotations 1.0 null Coelomic fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.187 SLC25A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76046 suicidal behavior GAD Gene-Disease Associations 1.0 null Beta Thalassemia DisGeNET Gene-Disease Associations 1.0 null BRD-K16403365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26247 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3442 BAHCC1 Pathway Commons Protein-Protein Interactions 1.0 null USP48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57371 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837655 proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.289199 Gestational Diabetes DisGeNET Gene-Phenotype Associations 1.0 null QGP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.336 lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.382131 BRD-K12343830 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19614 PNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60036 CRCGN017_MCF10A.WT.HP_24H:E10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.662 Ischemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.577 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1288 Asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.561 Interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.976 Schizophrenia CTD Gene-Disease Associations 1.0 2.88009 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Borderline Personality Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Perturb_8952_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 displayed GeneRIF Biological Term Annotations 1.0 null HBEGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31434 Perturb_10311_KO_Dkk3_SRP067265 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.34246 attention GeneRIF Biological Term Annotations 1.0 null hypothalamic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30342 CRCGN017_MCF10A.TP53.M_24H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.05252 DU145 CCLE Cell Line Gene Mutation Profiles 1.0 null window GeneRIF Biological Term Annotations 1.0 null GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30246 BRD-K05535086 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4883 neuroleptics GeneRIF Biological Term Annotations 1.0 null Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.0486 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Anterior cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.479 maltreated GeneRIF Biological Term Annotations 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 1.40288 mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null JIMT-1 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 REM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14913 positive regulation of developmental process GO Biological Process Annotations 2015 1.0 null Bowel dysfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.482 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02162 colonrectum_b HPA Tissue Sample Gene Expression Profiles 1.0 1.14995 RBMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10183 negative regulation of biological process GO Biological Process Annotations 2015 1.0 null TAOK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65264 BRD-K21990363 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07325 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.964 BRD-K67399222 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.88899 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054313 respect GeneRIF Biological Term Annotations 1.0 null CLK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69113 GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870278 CD200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55404 Enteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.358 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.20751 GTEX-S4Z8-0626-SM-4AD6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.65063 peripeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18356 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74622 PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Table_S6_Overlap_of_differentially_expressed_genes_in_Tg_HSP_EWS-FLI1_embryos_and_human_EWS-FLI1_signature_from_Smith_et_al_2006_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GSE152937_12_v_1_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88401 GLRB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00486542 GLO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89491 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948669 predisposing GeneRIF Biological Term Annotations 1.0 null RPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16886 Schizoaffective disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.312 intron GeneRIF Biological Term Annotations 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.894346 BRD-K25312635 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27892 SYNE1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1355 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE173873_2_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null LBX2 Pathway Commons Protein-Protein Interactions 1.0 null Cytotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.901 thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.087685 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.32377 TUBA4A Pathway Commons Protein-Protein Interactions 1.0 null Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4172 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48225 GTEX-PX3G-0426-SM-48U1C GTEx Tissue Sample Gene Expression Profiles 1.0 2.25693 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -1.2527 Carotid body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.912 GSE49929,GSE49931_1_v_0_irf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GATA2_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Self-Injurious Behavior DisGeNET Gene-Phenotype Associations 1.0 null SMARCA5 Pathway Commons Protein-Protein Interactions 1.0 null Head TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.738 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null L2HGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43993 regions GeneRIF Biological Term Annotations 1.0 null GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34352 BRD-K38510068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33642 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.831547 Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.888 CRCGN016_MCF10A.TP53.M_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.3046 Perturb_13143_KO_Tug1_SRP176442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.71232 JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.72708 adjustment disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.518805 SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7969 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8875876__F4 PFOCR Pathway Figure Associations 2024 1.0 null PIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75997 GSE210885_2_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Schizophrenia 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 ARH77 DepMap CRISPR Gene Dependency 1.0 5.00192 modified GeneRIF Biological Term Annotations 1.0 null RRM1 Pathway Commons Protein-Protein Interactions 1.0 null Seizures CTD Gene-Disease Associations 1.0 1.40092 NAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.76978 Gastroparesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.46 RPL35A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55306 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.683 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.856402 rs1805054 GeneRIF Biological Term Annotations 1.0 null Heart valve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.096 GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null culture medium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.860942 Organum vasculosum laminae terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.597 DPPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67047 THP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.914 MPPE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47935 hydroxylase1 GeneRIF Biological Term Annotations 1.0 null GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90679 part GeneRIF Biological Term Annotations 1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 0.884859 PMC9450187__F1 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-WH7G-0426-SM-3NMBJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828996 GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70117 fourth ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.386273 ZNF579 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60098 CDC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39605 Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Chronic kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.900112 Cognition Disorders CTD Gene-Disease Associations 1.0 1.25899 stomach GeneRIF Biological Term Annotations 1.0 null AJAP1 Pathway Commons Protein-Protein Interactions 1.0 null Personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.182 Depressive Disorder CTD Gene-Disease Associations 1.0 1.20427 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.979684 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.183 GSE234289_3_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null participates GeneRIF Biological Term Annotations 1.0 null GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30879 Bulimia nervosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.332 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.53481 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.698475 nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.76157 female reproductive endometrioid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.607714 snps GeneRIF Biological Term Annotations 1.0 null PCPA Guide to Pharmacology Chemical Ligands of Receptors 1.0 null Influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 more GeneRIF Biological Term Annotations 1.0 null FUT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05464 ORAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40333 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8315 ENOSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64729 Functional diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 ZNF10 MSigDB Cancer Gene Co-expression Modules 1.0 null ATG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98114 EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 135.933 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.07529 respiratory distress MGI Mouse Phenotype Associations 2023 1.0 null BRD-K32782599 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59567 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79549 Childhood Pineoblastoma DisGeNET Gene-Disease Associations 1.0 null carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052735 RPS6KA3 Hub Proteins Protein-Protein Interactions 1.0 null Adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.141 Inferior frontal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.734 SLC1A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9803 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -2.70794 ventrolateral part of isA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04238 tpq GeneRIF Biological Term Annotations 1.0 null cofactor GeneRIF Biological Term Annotations 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PWWP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62611 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.479702 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6403 neurofilament cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.264215 BRD-K95588139 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42489 TAF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.81763 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1831 basal forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221521 TNFRSF18 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15697 Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57175 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 associations GeneRIF Biological Term Annotations 1.0 null scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.968955 IMMT Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20409 TRIM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57568 Colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.354 UBE2Z CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44656 Familial hypertryptophanemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.185 BRD-K22246901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55283 GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.824013 GM2493 BioGPS Cell Line Gene Expression Profiles 1.0 0.982626 adhd GeneRIF Biological Term Annotations 1.0 null abnormal heart left ventricle pressure MPO Gene-Phenotype Associations 1.0 null KATNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04548 PMC7593679__F1 PFOCR Pathway Figure Associations 2023 1.0 null BRD-K21412601 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16344 female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.177029 gut TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.492963 avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01025 EPC1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173873_10_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-K01225799 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02575 Neurosecretory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.723 PMC6829839-13578_2019_352_MOESM2_ESM.xlsx-Table_2-SRG_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null RAVER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07952 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00344 medulla oblongata TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.2238 reproduction GAD High Level Gene-Disease Associations 1.0 0.298214 GSE205163,GSE205164_5_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null SHISA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4056 GSE171292_1_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures 1.0 null GPR141 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00551634 CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Suprachiasmatic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.487 TRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49529 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02252 duodenum_4b HPA Tissue Sample Gene Expression Profiles 1.0 0.96392 hek293 HPA Cell Line Gene Expression Profiles 1.0 1.1982 PRSS27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07224 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.089242 self-harm behavior GAD Gene-Disease Associations 1.0 null specificity GeneRIF Biological Term Annotations 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral tuberal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 Stress, Psychological HuGE Navigator Gene-Phenotype Associations 1.0 null BRD-K58643762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07765 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64062 vagus nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.404039 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 BL1012 (ZHX1) NURSA Protein Complexes 1.0 null marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.097052 Aorta Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.85212 Hypertension HuGE Navigator Gene-Phenotype Associations 1.0 null CRCGN015_HEPG2_48H:H01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.73479 NPY1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05518 catalytic activity GO Molecular Function Annotations 2015 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 2.88983 Pulmonary artery endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.461 GSE131649_4_v_10_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.330213 Systemic lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.552 quercetin-2499 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36261 BRD-K00620786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49094 striatum GeneRIF Biological Term Annotations 1.0 null CRCGN015_HEPG2_48H:K07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.08863 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.91301 anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057101 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 biosynthesis GeneRIF Biological Term Annotations 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15461 Amino acid metabolism WikiPathways Pathways 2024 1.0 null DNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94586 Thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.838 FU-OV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PLIN5_OE_GSE44192_482_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.905235 panic disorder GAD Gene-Disease Associations 1.0 null SF126 GDSC Cell Line Gene Expression Profiles -1.0 -2.08739 SAOS2 CCLE Cell Line Gene Mutation Profiles 1.0 null gf95 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.527 RNF125 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14727 CRCGN015_HEPG2_48H:I10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.88882 Type 1 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 Secretory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.459 GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00845 BRD-K54650634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45598 NCIN87 DepMap CRISPR Gene Dependency 1.0 5.15725 platelet degranulation GO Biological Process Annotations 2025 1.0 null non-neuronal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 HDL cholesterol GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 GTEX-PLZ4-2726-SM-3P61A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885221 trend GeneRIF Biological Term Annotations 1.0 null Biliary tract cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 differentiates GeneRIF Biological Term Annotations 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866838 PRKAR1B Pathway Commons Protein-Protein Interactions 1.0 null DRAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63368 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28972 metaanalysis GeneRIF Biological Term Annotations 1.0 null LIMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64428 compared GeneRIF Biological Term Annotations 1.0 null smallintestine_4d HPA Tissue Sample Gene Expression Profiles 1.0 1.05356 Catecholaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.234 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.286 GSE119978,GSE180930_6_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ZRANB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39771 Kidney Neoplasm DisGeNET Gene-Disease Associations 1.0 null PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null CACNA1G Pathway Commons Protein-Protein Interactions 1.0 null Cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.445 Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.497 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polymorphic GeneRIF Biological Term Annotations 1.0 null GTEX-X5EB-1626-SM-4E3IV GTEx Tissue Sample Gene Expression Profiles 1.0 1.0982 plastid-encoded plastid rna polymerase complex a COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.601487 Depressive Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null CYB5D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96507 Perturb_12058_KO_Stat5a/Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.833642 subjects GeneRIF Biological Term Annotations 1.0 null GTEX-XMK1-1726-SM-4B64Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.946439 likely GeneRIF Biological Term Annotations 1.0 null abnormal muscle contractility MPO Gene-Phenotype Associations 1.0 null linked GeneRIF Biological Term Annotations 1.0 null method GeneRIF Biological Term Annotations 1.0 null sex GeneRIF Biological Term Annotations 1.0 null Tetrahydrobiopterin HMDB Metabolites of Enzymes 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01275 serotonin-activated cation-selective channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.839 betathalassemia GeneRIF Biological Term Annotations 1.0 null GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873092 BRD-K53797069 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56918 substrate GeneRIF Biological Term Annotations 1.0 null histamine-gated chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.42 neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.162505 GTEX-VUSG-0726-SM-3GIK1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31554 contributing GeneRIF Biological Term Annotations 1.0 null limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.79347 PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT Rummagene Transcription Factor Associations 2026 1.0 null negative regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null DNMBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66608 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.55 TCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78903 Asi complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.206 GSE149903_0_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nuclear aryl hydrocarbon receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.612 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.1809 located GeneRIF Biological Term Annotations 1.0 null probability GeneRIF Biological Term Annotations 1.0 null Coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 RDES CCLE Cell Line Gene Expression Profiles 1.0 1.38611 Anterior cingulate area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0894 Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.413 Hypodermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.446 SKM1 CCLE Cell Line Gene Mutation Profiles 1.0 null nausea GAD Gene-Disease Associations 1.0 null tyrosine GeneRIF Biological Term Annotations 1.0 null NCIH2342 CCLE Cell Line Gene Mutation Profiles 1.0 null BRD-K36709933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.57319 BRD-K88936403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00316 Paranoid Schizophrenia DisGeNET Gene-Disease Associations 1.0 null FBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02571 FN1 Pathway Commons Protein-Protein Interactions 1.0 null Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.11905 GTEX-XMD1-0011-R3B-SM-4AT5R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861012 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65253 caucasian GeneRIF Biological Term Annotations 1.0 null ZNF358 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30203 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4467 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.892037 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.607 serve GeneRIF Biological Term Annotations 1.0 null CRCGN015_HEPG2_48H:F01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.3556 KCNMB2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00547707 Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.1311 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.08473 GTEX-V1D1-2626-SM-4JBJH GTEx Tissue Sample Gene Expression Profiles 1.0 0.989543 BRD-K73395020_-666_MCF7_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SKN3 DepMap CRISPR Gene Dependency 1.0 4.5792 OSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30401 frequencies GeneRIF Biological Term Annotations 1.0 null BRD-K59670689 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81585 respiratory system phenotype MPO Gene-Phenotype Associations 1.0 null Glial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.622 LIN28B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22623 CRCGN015_MCF10A.TP53.M_24H:O22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.04455 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.787105 Middle Insomnia DisGeNET Gene-Disease Associations 1.0 null SLC41A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62337 frequency GeneRIF Biological Term Annotations 1.0 null seeking GeneRIF Biological Term Annotations 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.254 uropygial gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.305001 Stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.02 PTPN21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53794 attributed GeneRIF Biological Term Annotations 1.0 null CRCGN015_HEPG2_48H:J16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.91124 hypertension GeneRIF Biological Term Annotations 1.0 null PMC3437946__F8 PFOCR Pathway Figure Associations 2024 1.0 null HNRNPF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14907 hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090085 Aromatic L-amino acid decarboxylase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.353 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96958 GTEX-U3ZN-2126-SM-4DXU1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859694 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SDHA Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QV44-2226-SM-447A3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18204 BRD-K73075421 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80173 group GeneRIF Biological Term Annotations 1.0 null GATA1-19941827-MEL-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null TIAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21924 CBX8 ENCODE Transcription Factor Targets 1.0 null GSE92434_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pulmonary artery endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.47 CFL1 Pathway Commons Protein-Protein Interactions 1.0 null SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 TMEM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.678 refractive error DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.083633 Midbrain reticular nucleus, retrorubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18356 Pars tuberalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.741 plastid-encoded plastid RNA polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.73 PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null MAST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4084 none GeneRIF Biological Term Annotations 1.0 null Communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.45 intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.752492 neuron projection GO Cellular Component Annotations 2015 1.0 null Hartnup disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 CRCGN014_HEPG2_3H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.53742 Post-Traumatic Stress Disorder DisGeNET Gene-Disease Associations 1.0 null NSMCE4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28146 Adrenal medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.745 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal muscle physiology MPO Gene-Phenotype Associations 1.0 null THEM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13044 KMT2A Pathway Commons Protein-Protein Interactions 1.0 null Placenta disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.096 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76507 GTEX-Q734-0326-SM-48U15 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42426 control GeneRIF Biological Term Annotations 1.0 null ATP13A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36777 Bulimia Nervosa HuGE Navigator Gene-Phenotype Associations 1.0 null GATA4-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.473 BRD-K97067262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10644 CCR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4579 bound GeneRIF Biological Term Annotations 1.0 null clopidol LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37501 Orbital area, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45754 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DHX40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0255 Esophageal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 LP533401 DGIdb Drug Targets 2026 1.0 3.30825 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50931 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null intermediate stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09477 confer GeneRIF Biological Term Annotations 1.0 null superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.4986 MAATS1 Pathway Commons Protein-Protein Interactions 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100520_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06627 FJX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3347 KYSE220 DepMap CRISPR Gene Dependency 1.0 3.63104 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null UBA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51266 BRD-K93941597 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34188 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31686 Osteoporosis DisGeNET Gene-Disease Associations 1.0 null Lipid storage disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.799 SKMEL2 DepMap CRISPR Gene Dependency 1.0 2.97029 Excretory canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.797 Fatty Liver DisGeNET Gene-Disease Associations 1.0 null Conduct disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.606 GTEX-TKQ1-1226-SM-4GICJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.925111 primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79421 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23862 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912982 LHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96605 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06551 Interstitial lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.137 dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.860311 TMEM50A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14279 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26702 diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 HADHB Pathway Commons Protein-Protein Interactions 1.0 null Diarrhea DisGeNET Gene-Phenotype Associations 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE90754_0_v_1_foxo1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CSAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86409 GSE155567_3_v_0_cd33_human RummaGEO Gene Perturbation Signatures 1.0 null layer 3 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14649 HCN channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.769 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.530028 connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.054063 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854256 DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 anatomical structure development GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hippocampal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21658 SMC3 ENCODE Transcription Factor Targets 1.0 null Cervix - Ectocervix GTEx Tissue Gene Expression Profiles 2023 1.0 1.32109 Adolescent Psychology HuGE Navigator Gene-Phenotype Associations 1.0 null MRPL51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93358 GSE139239_1_v_5_ddr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Small_Intestine-intestinal enteroendocrine cell Tabula Sapiens Gene-Cell Associations 1.0 3.11649 cellular process GO Biological Process Annotations 2015 1.0 null GTEX-PWOO-0826-SM-48TCL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01684 CYP2U1 Pathway Commons Protein-Protein Interactions 1.0 null C1QTNF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76628 RBFA Pathway Commons Protein-Protein Interactions 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.869 PIWIL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29146 HLA-DOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84828 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.82219 Tectum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.546 PRKAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07362 BRD-K52225720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42353 PPA2 Pathway Commons Protein-Protein Interactions 1.0 null lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38184 positive GeneRIF Biological Term Annotations 1.0 null principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29309 Electroconvulsive Therapy HuGE Navigator Gene-Phenotype Associations 1.0 null monoamine GeneRIF Biological Term Annotations 1.0 null SAPROPTERIN DGIdb Drug Targets 2026 1.0 1.65412 structure GeneRIF Biological Term Annotations 1.0 null HAUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48106 samples GeneRIF Biological Term Annotations 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02923 BRD-K49903196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12281 Synoviocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.125 effect GeneRIF Biological Term Annotations 1.0 null GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49624 MRPS36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37929 KLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32364 Obsessive-Compulsive Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null VCAM1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00654328 RPS27L Pathway Commons Protein-Protein Interactions 1.0 null colonrectum_a HPA Tissue Sample Gene Expression Profiles 1.0 0.87049 Pineal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.441 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.207 Bacterial biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.967 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K35124958 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32983 HOXA10 Pathway Commons Protein-Protein Interactions 1.0 null Medulla oblongata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.401 GSE235066_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null BRD-K23591737 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58914 ZSWIM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05762 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23459 Cognition Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-QEG5-1226-SM-447AR GTEx Tissue Sample Gene Expression Profiles 1.0 1.32766 GTEX-RUSQ-0526-SM-2TF72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10938 GSE119978,GSE180930_6_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null CDON CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58217 BRD-K60076175 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24444 depressive GeneRIF Biological Term Annotations 1.0 null CAPZA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.75392 ELOVL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91424 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GNRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79704 against GeneRIF Biological Term Annotations 1.0 null Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.829 p1Lim part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4513 ARFGAP1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K04714488 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1459 TEX264 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16149 Neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.25 insomnia GeneRIF Biological Term Annotations 1.0 null five GeneRIF Biological Term Annotations 1.0 null c1019g GeneRIF Biological Term Annotations 1.0 null bipolar disorder; depression GAD Gene-Disease Associations 1.0 null neuron spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.405193 illness GeneRIF Biological Term Annotations 1.0 null dkk1 GeneRIF Biological Term Annotations 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null α-propyldopacetamide Guide to Pharmacology Chemical Ligands of Receptors 1.0 null Midbrain central gray TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.532 dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60525 LN443 CCLE Cell Line Gene CNV Profiles 1.0 1.3394 Metabolism Reactome Pathways 2014 1.0 null GMEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.49397 obsessivecompulsive GeneRIF Biological Term Annotations 1.0 null ILF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76655 four GeneRIF Biological Term Annotations 1.0 null Panic Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DENND6B Pathway Commons Protein-Protein Interactions 1.0 null Dense core granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.534 zona incerta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242983 mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null DUSP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51126 Nail disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 RIOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38206 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15026 predict GeneRIF Biological Term Annotations 1.0 null BRD-K13697445 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22006 NPTX2 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05759 ZNF154 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48778 GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06567 BRD-K30628727 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22756 Gastric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.558 Creativeness HuGE Navigator Gene-Phenotype Associations 1.0 null mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K54285478 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47661 monocytic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.130289 GSE162892_3_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null sleep disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.14102 midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.30909 Impulsive Behavior DisGeNET Gene-Phenotype Associations 1.0 null BRD-K52634604 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03785 BRD-K25954314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15963 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5616 NCIH226 DepMap CRISPR Gene Dependency 1.0 3.90027 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08549 Tendon sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.571 abnormal serotonin level MPO Gene-Phenotype Associations 1.0 null ALVA31 BioGPS Cell Line Gene Expression Profiles 1.0 1.35196 Nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.164 abnormal cardiac muscle contractility MPO Gene-Phenotype Associations 1.0 null GTEX-NL3H-0008-SM-4E3HU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22486 IL1B Pathway Commons Protein-Protein Interactions 1.0 null PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-MXD1_MXD1 Rummagene Transcription Factor Associations 2026 1.0 null FRMPD4 Pathway Commons Protein-Protein Interactions 1.0 null Respiratory chain complex II COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.349 GSE149903_5_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null binding GO Molecular Function Annotations 2015 1.0 null GTEX-TMMY-0726-SM-33HBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.85493 modulating GeneRIF Biological Term Annotations 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59638 beckwith-wiedemann syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.31029 BRD-K17040651 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08407 sclerosing GeneRIF Biological Term Annotations 1.0 null Placental membrane TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.012 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.802 Nuclear membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.708 DMS-53 GDSC Cell Line Gene Expression Profiles 1.0 1.72315 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.864734 Scleroderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.481 LHX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60777 sliding GeneRIF Biological Term Annotations 1.0 null Gut epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.89 httlpr GeneRIF Biological Term Annotations 1.0 null NUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7888 BRD-K99412981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28782 Tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.681 geneenvironment GeneRIF Biological Term Annotations 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GLRX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87308 NCIH69 CCLE Cell Line Gene Expression Profiles 1.0 2.08592 neonatal period electroclinical syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.367779 astrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23781 DDRGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.471 Carcinoma CTD Gene-Disease Associations 1.0 1.3903 mastocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.23473 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19021 BRD-K45811188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07559 L-929 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.866 Necrotizing Enterocolitis In Fetus Or Newborn DisGeNET Gene-Disease Associations 1.0 null ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -1.62641 Dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.52 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.17026 ASGR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00638243 Midbody COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.468 endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048646 X-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 GSDMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02334 subarachnoid space TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.735559 GTEX-P44H-1026-SM-3NM96 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21222 SSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78645 Metabolic dysfunction-associated steatohepatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Submucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.949 indicated GeneRIF Biological Term Annotations 1.0 null dystonia, DOPA-responsive DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.042862 BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8346 behaviors GeneRIF Biological Term Annotations 1.0 null GTEX-WRHU-1326-SM-4E3K7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.98117 SPACA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.758 t52-hippocampus_male_2w MoTrPAC Rat Endurance Exercise Training -1.0 -3.66255 NCI-H226Br cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.961 Somatodendritic compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.873 Mitral valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.282 GNG11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47662 Migraine Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Fe2+ HMDB Metabolites of Enzymes 1.0 null PMC7534062__F8 PFOCR Pathway Figure Associations 2023 1.0 null psych GAD High Level Gene-Disease Associations 1.0 0.655953 melanocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214388 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14519 Contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 TNFAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92997 orand GeneRIF Biological Term Annotations 1.0 null Curli COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.969 PCDHB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43023 GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.981799 PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Basomedial amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03214 CYB5R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38376 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U1-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null External female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.918 stable GeneRIF Biological Term Annotations 1.0 null GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03027 changes GeneRIF Biological Term Annotations 1.0 null intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70721 CRCGN017_MCF10A.TP53.M_24H:K23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.3427 inversion GeneRIF Biological Term Annotations 1.0 null psychoses GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PARP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58461 Epithelioma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.2752 Toxic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.634 PMC5479833__F4 PFOCR Pathway Figure Associations 2023 1.0 null GTEX-OHPM-0426-SM-3TW8V GTEx Tissue Sample Gene Expression Profiles 1.0 1.60094 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.13216 BTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05649 Infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.896 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00309 GTEX-R53T-0826-SM-48FCP GTEx Tissue Sample Gene Expression Profiles 1.0 1.55983 Cytosolic aryl hydrocarbon receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.862 aggressive behavior GAD Gene-Disease Associations 1.0 null GCH1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.487 Retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 catalytic complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.056522 MTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4573 GTEX-WH7G-0626-SM-4LVMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.64435 Irritable Bowel Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null SNU899 CCLE Cell Line Gene Mutation Profiles 1.0 null ZNF583 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74211 enzymes GeneRIF Biological Term Annotations 1.0 null MRPS21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91872 Dental Enamel Hypoplasia DisGeNET Gene-Disease Associations 1.0 null epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.08723 BRD-K68540120 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47949 GTEX-X4EO-0126-SM-3P5YN GTEx Tissue Sample Gene Expression Profiles 1.0 0.920767 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.97733 GTEX-QXCU-0926-SM-48FEP GTEx Tissue Sample Gene Expression Profiles 1.0 2.42314 Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.504 Perturb_8949_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.71693 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4489 nearby GeneRIF Biological Term Annotations 1.0 null BRD-K22139757 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14805 GSE188870,GSE188871_4_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_12141_KO_Lgals9_ERP122370 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60085 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.499042 CCNH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00350121 Transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.799 Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Left colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.883 cell part LOCATE Predicted Protein Localization Annotations 1.0 null ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5957 combined GeneRIF Biological Term Annotations 1.0 null BHLHA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53181 GATA3-21878914-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BRD-K61984373 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13974 Junctional zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.768 mRNA_ATF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null WASF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.60941 GTEX-S33H-0726-SM-4AD6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.49698 HLCS LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00545472 myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.087241 GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23795 rn-46a cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.13811 synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.503099 Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29501 CTTNBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69921 Supportive connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.378 Axon hillock COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.53 Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.23904 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null conduct disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.562946 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.505944 SPSB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53727 GTEX-RN64-0526-SM-2TC5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.0925 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.39105 Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.19344 PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT Rummagene Transcription Factor Associations 2026 1.0 null GSE144120_3_v_1_plcg2_human RummaGEO Gene Perturbation Signatures 1.0 null DYNLRB1 Pathway Commons Protein-Protein Interactions 1.0 null Autistic Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Melancholic depression DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.739 GTEX-PW2O-0426-SM-48TCC GTEx Tissue Sample Gene Expression Profiles 1.0 2.21907 cellular biogenic amine metabolic process GO Biological Process Annotations 2015 1.0 null CLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15946 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08922 ileum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.364886 CRCGN017_MCF10A.WT.HP_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.61815 CLSTN1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QXCU-1926-SM-48FE4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07067 Narcolepsy HuGE Navigator Gene-Phenotype Associations 1.0 null Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40787 PMC11732233-mmc1.pdf-24-PRDM2_PRDM2 Rummagene Transcription Factor Associations 2026 1.0 null estrone-3071 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hypoparathyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.29118 Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Antennal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 GTEX-WY7C-2826-SM-3NB3Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.0877 properties GeneRIF Biological Term Annotations 1.0 null BRD-K93032100 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02587 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.076489 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912982 KCNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0265 trait GeneRIF Biological Term Annotations 1.0 null well GeneRIF Biological Term Annotations 1.0 null BRD-K16879434 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06866 BRD-K85972696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18227 hyperopia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.106617 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.9768 amine metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K43775480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76109 FN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82375 tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06382 EIF2AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17494 PMC4147234__F1 PFOCR Pathway Figure Associations 2023 1.0 null SLC16A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16747 ETV6 Pathway Commons Protein-Protein Interactions 1.0 null Megacolon DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.264 lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.984477 lateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32797 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null therapy GeneRIF Biological Term Annotations 1.0 null UMC-11 GDSC Cell Line Gene Expression Profiles 1.0 2.13708 antisocial GeneRIF Biological Term Annotations 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2215 AKT_UP_MTOR_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Proboscis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.587 carcinoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.926764 MAX Pathway Commons Protein-Protein Interactions 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22906 ECC12 GDSC Cell Line Gene Expression Profiles 1.0 1.41914 MATN4 Pathway Commons Protein-Protein Interactions 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11584 Crypt TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.956 AR ChEA Transcription Factor Targets 1.0 null BRD-K80483148 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26387 CRCGN009_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6203 GSE232631_5_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 17009876-tableS1a GeneSigDB Published Gene Signatures 1.0 null temporomandibular joint disorders GAD Gene-Disease Associations 1.0 null TMEM104 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94861 nuclear replisome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.16298 Perturb_17144_OE_Xbp1_ERP110244 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.88318 Arteriosclerotic cardiovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 PSMA3 Pathway Commons Protein-Protein Interactions 1.0 null QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 TUT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49551 Locus ceruleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.582 BRD-K04367224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12873 MOGGUVW CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-WFG8-1826-SM-4LVM4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1434 layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28018 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.639 Nerve plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.963 SAP30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91125 peer GeneRIF Biological Term Annotations 1.0 null YJU2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65728 showed GeneRIF Biological Term Annotations 1.0 null SENP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0266 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.907825 Intestinal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.632 provide GeneRIF Biological Term Annotations 1.0 null Dorsal nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.538 FLNA Pathway Commons Protein-Protein Interactions 1.0 null EHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47316 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.965383 NKX2-5-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059029 Neuropsychological Tests HuGE Navigator Gene-Phenotype Associations 1.0 null NFIL3 Pathway Commons Protein-Protein Interactions 1.0 null MAP7D1 Pathway Commons Protein-Protein Interactions 1.0 null CYRIA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00529102 disorder GeneRIF Biological Term Annotations 1.0 null RPS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22492 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.625319 GSE214685_0_v_1_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null Brain capillary endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.64 SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 describe GeneRIF Biological Term Annotations 1.0 null psi2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.511 connecting stalk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.102514 CRCGN015_HEPG2_48H:G05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.76654 Pulmonary artery smooth muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.511 htr5a GeneRIF Biological Term Annotations 1.0 null Epididymal white adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.991 Cystic fibrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 IL17RC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60218 KYSE450 CCLE Cell Line Gene Expression Profiles 1.0 1.61492 angular gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.965012 normal variation GAD Gene-Disease Associations 1.0 null LGALS1 Pathway Commons Protein-Protein Interactions 1.0 null HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.14942 Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pars compacta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274744 Cancellous bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.301 PMC8144624-41598_2021_90212_MOESM2_ESM.xlsx-6_hrs_ps_LPS-merged_Gene_ID_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Area postrema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.987 PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null TUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56784 spastic quadriplegia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.430017 Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.339 GTEX-WFG7-0926-SM-4LMK7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.86249 Gastrointestinal endocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.498 SOGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68817 KBTBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92002 variations GeneRIF Biological Term Annotations 1.0 null BRD-K80198069 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32568 FANCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61137 GM97 BioGPS Cell Line Gene Expression Profiles 1.0 2.13966 H2AC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48173 GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null dexamethasone_mus musculus_gpl339_gse2342 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null 12869505-Table2 GeneSigDB Published Gene Signatures 1.0 null Cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.312 crystal GeneRIF Biological Term Annotations 1.0 null anterior GeneRIF Biological Term Annotations 1.0 null SLITRK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68817 UBL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5852 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4579 ABCB1 Pathway Commons Protein-Protein Interactions 1.0 null Axillary Web Syndrome DisGeNET Gene-Disease Associations 1.0 null SOX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06752 SCH DepMap CRISPR Gene Dependency 1.0 8.60626 Generalized anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.556 prerubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05569 nucleoside GeneRIF Biological Term Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42778 Metabolism of amino acids and derivatives Reactome Pathways 2014 1.0 null thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.096801 Pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.731 Perturb_15790_KO_Il19_SRP356176 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.74312 CDKN2AIPNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51918 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.50323 healthy GeneRIF Biological Term Annotations 1.0 null fibre tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.189548 ARHGAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89471 rectum HPA Tissue Protein Expression Profiles 1.0 1.6514 BRD-K56916066 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70696 Perturb_3818_KO_Tnfrsf1a_SRP126581 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.28941 ATP8B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61696 C10orf88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23445 icSARS-Cov_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.58923 PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841536 Fibromyalgia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.463149 Sapropterin HMDB Metabolites of Enzymes 1.0 null cefalonium-2921 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PHETA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99854 BRD-K81665173 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46558 Schizophrenia DisGeNET Gene-Disease Associations 1.0 null LIMS1 Pathway Commons Protein-Protein Interactions 1.0 null mastocytoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.15806 Type 1 diabetes mellitus 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 T-tubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.079 Mild cognitive impairment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 BUB1 Pathway Commons Protein-Protein Interactions 1.0 null astroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.263327 ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.82708 Mental Depression DisGeNET Gene-Disease Associations 1.0 null neuronal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.169197 PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61332 Systemic scleroderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 RBCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01482 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4848 Pancreatic alpha cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.556 bipolar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298524 SRF-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null system GeneRIF Biological Term Annotations 1.0 null amygdaloid complex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03117 organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Psychotic Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null USP36 Pathway Commons Protein-Protein Interactions 1.0 null BRL-3A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.964 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.350452 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6669 intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33618 alters GeneRIF Biological Term Annotations 1.0 null Homicidal DisGeNET Gene-Phenotype Associations 1.0 null genotype GeneRIF Biological Term Annotations 1.0 null Antral mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.393 BRD-K39247583 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15255 kleine-levin syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.505356 characteristics GeneRIF Biological Term Annotations 1.0 null Synovium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.574 PRR11 Pathway Commons Protein-Protein Interactions 1.0 null MYH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16761 Gastrointestinal smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.693 CCRF-CEM COSMIC Cell Line Gene Mutation Profiles 1.0 null RAD50 Pathway Commons Protein-Protein Interactions 1.0 null Sleeplessness DisGeNET Gene-Phenotype Associations 1.0 null GTEX-NL3H-0011-R1a-SM-48TDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16635 hsa-miR-3173-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HTRA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64328 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02717 Rheumatoid arthritis disease specific synovial fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.747 mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41317 ZNF354B Pathway Commons Protein-Protein Interactions 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5569 GGTLC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63979 CROCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85634 smoking GAD Gene-Disease Associations 1.0 null GTEX-N7MT-1426-SM-3LK5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.07805 GSE155305_3_v_0_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null eating disorders GAD Gene-Disease Associations 1.0 null studied GeneRIF Biological Term Annotations 1.0 null CDK5RAP2 Pathway Commons Protein-Protein Interactions 1.0 null STK36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96753 Cholangiocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 NCIH82 CCLE Cell Line Gene Expression Profiles 1.0 1.90628 SGOL2 Pathway Commons Protein-Protein Interactions 1.0 null CIRBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.18925 TMEM179B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98841 cell projection GO Cellular Component Annotations 2015 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828984 PRKACA Hub Proteins Protein-Protein Interactions 1.0 null SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.36639 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE162892_3_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null serotonergic GeneRIF Biological Term Annotations 1.0 null FOXJ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82081 Intestinal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.863 cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null indolalkylamine metabolic process GO Biological Process Annotations 2015 1.0 null neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.875329 dorsolateral (non-cerebellar) part of isA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10584 oral cavity cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.07788 Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.504 Schizophrenia, Paranoid HuGE Navigator Gene-Phenotype Associations 1.0 null DDX47 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K94409042 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39375 Muscle cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.177 adrenal medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.310059 GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10583 Cecum mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.406315 Chronic obstructive pulmonary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 severe GeneRIF Biological Term Annotations 1.0 null PMC5575491__F5 PFOCR Pathway Figure Associations 2024 1.0 null hsa-miR-3929 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE118617,GSE118619_2_v_3_foxp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null I-kappaB/NF-kappaB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.631 BRD-K01083922 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37059 THAP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76982 POLG Pathway Commons Protein-Protein Interactions 1.0 null Parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.18 common GeneRIF Biological Term Annotations 1.0 null NOMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35034 NRD1 Pathway Commons Protein-Protein Interactions 1.0 null FBXL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06321 SRSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31979 superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44685 bone remodeling GO Biological Process Annotations 2015 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null haplotype GeneRIF Biological Term Annotations 1.0 null periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09688 intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60935 Fetal Death CTD Gene-Disease Associations 1.0 1.15593 GTEX-NL3H-0011-R5a-SM-2I3GB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.142 amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41832 BRD-K52232548 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05613 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.974 ACACB Pathway Commons Protein-Protein Interactions 1.0 null BRWD1 Pathway Commons Protein-Protein Interactions 1.0 null except GeneRIF Biological Term Annotations 1.0 null Enteroendocrine cell_Colon_Mouse CellMarker Gene-Cell Type Associations 1.0 null tongue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.463013 SACS Pathway Commons Protein-Protein Interactions 1.0 null area postrema TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.469987 GSE100316_7_v_1_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null Vitamin D sensitive calcium signaling in depression WikiPathways Pathways 2024 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU423 CCLE Cell Line Gene Expression Profiles -1.0 -2.01384 CUEDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17697 NGF-stimulated transcription Reactome Pathways 2024 1.0 null ADD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27825 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34063 BRD-K28107038 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22683 Melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.763 require GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67312 Signaling by NTRK1 (TRKA) Reactome Pathways 2024 1.0 null Integrin alpha4-beta7 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.701 neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 SAMD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19323 Sensory dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.439 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9947 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06142 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.50008 Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.277 GCIY CCLE Cell Line Gene CNV Profiles 1.0 1.52103 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.583 nervous GeneRIF Biological Term Annotations 1.0 null GTEX-WHWD-0426-SM-3LK83 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13405 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.199 GSE168401_1_v_0_harmine_human RummaGEO Drug Perturbation Signatures 1.0 null somatoform GeneRIF Biological Term Annotations 1.0 null OGA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00651633 BRD-K53050301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43894 impaired muscle contractility MPO Gene-Phenotype Associations 1.0 null GTEX-VJYA-1026-SM-4KL21 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45086 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Midbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.426 Tetrahydrobiopterin MW Enzyme Metabolite Associations 1.0 null obsessive-compulsive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.089 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.231527 BRD-K25675728 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27316 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26462 ZNF660 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34856 mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.895861 Abdominal Symptom DisGeNET Gene-Phenotype Associations 1.0 null PMC4417587__F1 PFOCR Pathway Figure Associations 2023 1.0 null KARS Pathway Commons Protein-Protein Interactions 1.0 null statistically GeneRIF Biological Term Annotations 1.0 null Pars compacta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.968 Fetal Growth Retardation DisGeNET Gene-Phenotype Associations 1.0 null GTEX-QMRM-1226-SM-447C6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.872596 PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.877668 GSE139239_2_v_6_ddr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.607 catecholaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.881204 Stomach cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 Hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.202 Primary pulmonary hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895839 BRD-K42789863 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61538 modulated GeneRIF Biological Term Annotations 1.0 null t52-hippocampus_consensus MoTrPAC Rat Endurance Exercise Training 1.0 3.11371 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null when GeneRIF Biological Term Annotations 1.0 null cutaneous mastocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.42937 GSE147662_3_v_5_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole CTD Gene-Chemical Interactions 1.0 null elderly GeneRIF Biological Term Annotations 1.0 null LCAT MSigDB Cancer Gene Co-expression Modules 1.0 null Universal_Human_Reference Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.01811 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54434 ANXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66846 Penis_Foreskin_Melanocyte_Primary_Cells_skin01 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -2.49741 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26565 Amino Acid metabolism(Mus musculus) WikiPathways Pathways 2014 1.0 null PLA2G4A Pathway Commons Protein-Protein Interactions 1.0 null TMEM106A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18725 Psoriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 there GeneRIF Biological Term Annotations 1.0 null K2 COSMIC Cell Line Gene Mutation Profiles 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53036 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1182 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.42516 Mastocytoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.119 Dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.285 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79322 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.367 BRD-K30727702 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58347 autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.739488 Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24041 leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.820026 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CBFB Pathway Commons Protein-Protein Interactions 1.0 null Motoneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.911 USP48 Pathway Commons Protein-Protein Interactions 1.0 null HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.78518 dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04852 GTEX-WCDI-0426-SM-4GIAL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01585 GTEX-S3XE-0226-SM-4AD6I GTEx Tissue Sample Gene Expression Profiles 1.0 0.903556 GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77876 POLR3A Pathway Commons Protein-Protein Interactions 1.0 null RIDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5089 visceral GeneRIF Biological Term Annotations 1.0 null GTEX-U3ZN-0526-SM-4DXTH GTEx Tissue Sample Gene Expression Profiles 1.0 1.8387 heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.395331 BRD-K40809590 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.65549 Duodenal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.42 oxidase GeneRIF Biological Term Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colonic GeneRIF Biological Term Annotations 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24486 CDV3 Pathway Commons Protein-Protein Interactions 1.0 null SNX19 Pathway Commons Protein-Protein Interactions 1.0 null other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.833642 Pain disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 Plasma membrane bounded cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.293 TRMT112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10901 ZNF511 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66951 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00289 Colon transversum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.711 Neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null lymphoblastoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061452 DYNC2I1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28198 Sleep disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.607 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35172 regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15819 regional GeneRIF Biological Term Annotations 1.0 null YIPF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82207 PMC2753863__F1 PFOCR Pathway Figure Associations 2024 1.0 null breast HPA Tissue Protein Expression Profiles -1.0 -0.873603 GTEX-XBED-0726-SM-4GIAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.14819 Perturb_17345_KO_E4bp4_SRP165985 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SUDHL10 CCLE Cell Line Gene Expression Profiles 1.0 1.37948 Aromatic amino acid hydroxylase InterPro Predicted Protein Domain Annotations 1.0 null Adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Caput epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.54 piebaldism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.32774 mRNA_TCEA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.631 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59609 Oxyntic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.188 tissue remodeling GO Biological Process Annotations 2015 1.0 null Gonadal sheath cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.95 antidepressant GeneRIF Biological Term Annotations 1.0 null SH3D19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3123 SNU1040 CCLE Cell Line Gene CNV Profiles -1.0 -1.4034 mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02863 TDG Pathway Commons Protein-Protein Interactions 1.0 null Coronavirus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 tumours GeneRIF Biological Term Annotations 1.0 null TEAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79216 comorbid GeneRIF Biological Term Annotations 1.0 null striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903816 FOSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06316 BRD-K53816426 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07955 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9871 Alcohol Use Disorder DisGeNET Gene-Disease Associations 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880066 ZNF492 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43989 CDC42EP1 Pathway Commons Protein-Protein Interactions 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null roles GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ8-0011-R2a-SM-2TC6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10068 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1396 Gut granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.877 Globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.035 indole-containing compound biosynthetic process GO Biological Process Annotations 2023 1.0 null viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.164786 carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.082218 Parathyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 CUX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68696 GSE119978,GSE180930_0_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null htr1b GeneRIF Biological Term Annotations 1.0 null dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37175 neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.319863 Matrilin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.3 Umbilical cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.402 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC7933006__F2 PFOCR Pathway Figure Associations 2023 1.0 null PMC10253150__F7 PFOCR Pathway Figure Associations 2024 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null LOXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43 SNU478 CCLE Cell Line Gene Expression Profiles -1.0 -1.86908 GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40916 SIPA1L3 Pathway Commons Protein-Protein Interactions 1.0 null ZNF831 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65867 primary metabolic process GO Biological Process Annotations 2015 1.0 null DYNC1LI1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K17659275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08406 single-organism process GO Biological Process Annotations 2015 1.0 null BRD-K62612761 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85167 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.24626 BRD-K90480740 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0498 MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null childhood GeneRIF Biological Term Annotations 1.0 null BRD-K99525048 LINCS L1000 CMAP Chemical Perturbation 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1.0 null altered GeneRIF Biological Term Annotations 1.0 null VPS45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99373 neuronal cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.745929 ZNF106 Pathway Commons Protein-Protein Interactions 1.0 null Α-PROPYLDOPACETAMIDE DGIdb Drug Targets 2026 1.0 1.10275 Cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.093 AKAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7566 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.286 POLR1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88402 Heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.582 PMC7593679__F1 PFOCR Pathway Figure Associations 2024 1.0 null Caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.177 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null liver_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.22533 Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SYS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42172 Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30953 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null PDLIM4 Pathway Commons Protein-Protein Interactions 1.0 null Medial septum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.723 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9836 GTEX-S95S-0226-SM-4B656 GTEx Tissue Sample Gene Expression Profiles 1.0 2.0095 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29799 SWSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87919 PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-MXD1_MXD1 Rummagene Transcription Factor Associations 2026 1.0 null dna replication factor a complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.165463 BRD-K41172555 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19077 date GeneRIF Biological Term Annotations 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.030752 JUN Pathway Commons Protein-Protein Interactions 1.0 null CDKN2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28864 SIVA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29925 GSE149880_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Generalized Anxiety Disorder DisGeNET Gene-Disease Associations 1.0 null short GeneRIF Biological Term Annotations 1.0 null GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05588 BRD-K67522096 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26411 NDST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05848 periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18589 Lymphocytic colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.836 GATA4-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K50498614 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35255 HCT116 DepMap CRISPR Gene Dependency 1.0 2.61582 Deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.249 WDTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52389 inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.18368 GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01191 Sclerosis HuGE Navigator Gene-Phenotype Associations 1.0 null C4A Pathway Commons Protein-Protein Interactions 1.0 null PIGQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81825 Depression DisGeNET Gene-Disease Associations 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Nausea HuGE Navigator Gene-Phenotype Associations 1.0 null MKN1 CCLE Cell Line Gene Expression Profiles -1.0 -2.06766 HOXB5 Pathway Commons Protein-Protein Interactions 1.0 null Disease Susceptibility HuGE Navigator Gene-Phenotype Associations 1.0 null first GeneRIF Biological Term Annotations 1.0 null marrow GeneRIF Biological Term Annotations 1.0 null BRD-K01125214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02083 abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 rare GeneRIF Biological Term Annotations 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 BRD-K71537579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13386 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.835 LHCGR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00788815 BRD-K21635266 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05577 GTEX-QDT8-0326-SM-32PL1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884158 Weight Gain HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-XUW1-1126-SM-4BONZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.57983 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.975782 weight gain GAD Gene-Disease Associations 1.0 null GTEX-XUJ4-0626-SM-4BOOO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972781 inclusion body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.211587 GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Chitosan CTD Gene-Chemical Interactions 1.0 null GTEX-PLZ5-0426-SM-3P612 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40468 hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36302 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCOR2 Pathway Commons Protein-Protein Interactions 1.0 null nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.083954 behavior GeneRIF Biological Term Annotations 1.0 null ethnic GeneRIF Biological Term Annotations 1.0 null lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.163111 anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1194 Edema HuGE Navigator Gene-Phenotype Associations 1.0 null TNPO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71068 GTEX-O5YW-0326-SM-2I5EI GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 NCIH1869 CCLE Cell Line Gene CNV Profiles -1.0 -1.37601 hsa-miR-4429 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Vitelline envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.551 Gastrointestinal allergy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.167 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.737 BRD-K66734120 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12509 COVID-19 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 GLB1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88995 Large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.391 BRD-K28057105 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.52549 BRD-K37203382 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22643 Psychological Tests HuGE Navigator Gene-Phenotype Associations 1.0 null female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.052032 BRD-K60905563 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0786 BRD-K34445094 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01991 acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.223 KREMEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25335 pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.862228 SMYD4 Pathway Commons Protein-Protein Interactions 1.0 null CRCGN015_HEPG2_48H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.1142 ST6GALNAC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45971 cerebellar cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.508242 Hyperinsulinism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.233 functional gastric disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.461639 cyclic-amp-dependent-protein-kinases Phosphosite Textmining Biological Term Annotations 1.0 null Peripheral nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.431 POP4 Pathway Commons Protein-Protein Interactions 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01581 heterosis GeneRIF Biological Term Annotations 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79371 reuniens nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01616 GCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06079 XF-498 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.585 enteric nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.527928 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51176 Colon muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.494 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1954 CPNE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50773 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.36 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 cuneiform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24138 INSM1 Pathway Commons Protein-Protein Interactions 1.0 null Eating disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.805 Female pudendum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.921 GTEX-QMRM-0626-SM-447BQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.57719 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78222 ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.176389 DMS153 CCLE Cell Line Gene Expression Profiles 1.0 1.97138 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-O5YV-0626-SM-3LK64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13558 Mucous gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.83 regulated GeneRIF Biological Term Annotations 1.0 null ALPK3 Pathway Commons Protein-Protein Interactions 1.0 null Pseudohermaphroditism DisGeNET Gene-Disease Associations 1.0 null Pineoblastoma DisGeNET Gene-Disease Associations 1.0 null Water HMDB Metabolites of Enzymes 1.0 null MM77 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10078 all GeneRIF Biological Term Annotations 1.0 null Apical junction complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.306 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.04031 Hypodermal seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.723 GSE65617_0_v_4_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null essential GeneRIF Biological Term Annotations 1.0 null ADF cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.642 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FANCM Pathway Commons Protein-Protein Interactions 1.0 null LRP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36652 GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles 1.0 1.05743 bone marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085774 BRD-K45380779 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31919 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Anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.445 acute GeneRIF Biological Term Annotations 1.0 null ABCA9 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-POYW-1126-SM-48TCI GTEx Tissue Sample Gene Expression Profiles 1.0 1.0272 Schizophrenia HuGE Navigator Gene-Phenotype Associations 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.611625 GTEX-RU1J-0326-SM-46MUM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826065 andor GeneRIF Biological Term Annotations 1.0 null Calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.998 KYSE70 CCLE Cell Line Gene CNV Profiles 1.0 1.49074 TCF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17339 risk-taking behavior in a gambling task GAD Gene-Disease Associations 1.0 null GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles 1.0 1.05101 glutathione-transferase Phosphosite 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PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 myc_00000000_e13dot5_heart_lof_mouse_gpl4865_gse7162 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.087531 RALGAPA1 Pathway Commons Protein-Protein Interactions 1.0 null CEP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61051 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26996 Bladder Neoplasm DisGeNET Gene-Disease Associations 1.0 null GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null Gastritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.208 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05334 PMC4439562__F1 PFOCR Pathway Figure Associations 2023 1.0 null OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.13273 BRD-K50712773 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54562 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null wernicke-korsakoff syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.717232 Mental Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null calcium-calmodulin-dependent-protein-kinases Phosphosite Textmining Biological Term Annotations 1.0 null most GeneRIF Biological Term Annotations 1.0 null GTEX-S32W-2426-SM-2XCAT GTEx Tissue Sample Gene Expression Profiles 1.0 0.933297 bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042489 Harderian gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.527 BRD-K07534805 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22714 GTEX-WFON-0526-SM-4LVLY GTEx Tissue Sample Gene Expression Profiles 1.0 1.24961 intestinal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.568424 NCI-H2196 GDSC Cell Line Gene Expression Profiles 1.0 2.6663 AHNAK Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XGQ4-1326-SM-4GIDU GTEx Tissue Sample Gene Expression Profiles 1.0 1.21511 THOC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00538 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Syp1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.668 BRD-K39624517 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29757 epithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052618 Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.701 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.87 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61807 negatively GeneRIF Biological Term Annotations 1.0 null pericellular basket COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.197662 ileocecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.377996 BRD-K08504955 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21485 detected GeneRIF Biological Term Annotations 1.0 null duodenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.267102 KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.56185 signal GeneRIF Biological Term Annotations 1.0 null Nuclear inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.968 PMC2753863__F1 PFOCR Pathway Figure Associations 2023 1.0 null PMC4439562__F1 PFOCR Pathway Figure Associations 2024 1.0 null thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.234225 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 plateletderived GeneRIF Biological Term Annotations 1.0 null Human - Fetal Development - L1 - Neuroendocrine cells HuBMAP Azimuth Cell Type Annotations 1.0 null 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10636 GTEX-QDVN-0226-SM-48TZ9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.954304 BRD-K52136059 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35354 HERPUD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30907 blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.887133 IgG4-related disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.383 EVSAT CCLE Cell Line Gene CNV Profiles 1.0 1.44458 PGRMC1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00356053 Vasculature-smooth muscle cell Tabula Sapiens Gene-Cell Associations 1.0 12.8583 decreased cardiac muscle contractility MPO Gene-Phenotype Associations 1.0 null adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.765711 leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060534 Adenohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.212 Brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.688 depressive disorder, major; bipolar disorder; affective psychoses GAD Gene-Disease Associations 1.0 null Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.42238 NCI-H2029 GDSC Cell Line Gene Expression Profiles 1.0 2.58022 nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06803 alzheimers GeneRIF Biological Term Annotations 1.0 null APEX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68043 Hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.567 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17234 endogenous depression DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.160761 HEL9217 DepMap CRISPR Gene Dependency 1.0 3.49869 Ventral globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.725 GK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71186 ADAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93869 pain disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.273664 metabolic GAD High Level Gene-Disease Associations 1.0 0.295739 basophilic leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.183067 GTEX-T6MN-1126-SM-4DM71 GTEx Tissue Sample Gene Expression Profiles 1.0 3.60143 nterminal GeneRIF Biological Term Annotations 1.0 null arterial endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220152 marfan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.224196 Tryptophan MW Enzyme Metabolite Associations 1.0 null endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220152 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypertension GAD Gene-Disease Associations 1.0 null PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6 Rummagene Transcription Factor Associations 2026 1.0 null addiction GeneRIF Biological Term Annotations 1.0 null ATP11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41444 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.873603 RICTOR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52878 BRD-K17850764 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00691 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.685 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.529618 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.826831 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87293 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27093 Neuroendocrine tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.621 C1orf35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33945 orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36975 macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214202 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.393 Sinusoidal trophoblast giant cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.537 GTEX-SIU7-1626-SM-4BRUK GTEx Tissue Sample Gene Expression Profiles 1.0 1.31768 SOX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53983 BTN2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36976 REST ChEA Transcription Factor Targets 1.0 null Mucus layer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.924 RALBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53416 tests GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZH-1326-SM-3NB1H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31295 DPEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63158 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.49032 PADI2 Pathway Commons Protein-Protein Interactions 1.0 null CDC42BPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81017 BRD-K92701606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26142 molecular_function GO Molecular Function Annotations 2015 1.0 null PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null CLC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00587456 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1963 behaviour GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.935969 Unipolar Depression DisGeNET Gene-Disease Associations 1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4225 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34281 CD74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36201 SUCNR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00524881 molecular layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28752 CRCGN013_HEPG2_24H:O06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.58122 nondiabetic GeneRIF Biological Term Annotations 1.0 null violent GeneRIF Biological Term Annotations 1.0 null Pulmonary Arterial Hypertension DisGeNET Gene-Disease Associations 1.0 null NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27625 BRD-K45799338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5328 comt GeneRIF Biological Term Annotations 1.0 null horsetail-astral microtubule array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.037 germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062783 presented GeneRIF Biological Term Annotations 1.0 null duodenum GeneRIF Biological Term Annotations 1.0 null HMGN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54632 Hindgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.126 Peyer's gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 hypersensitivity reaction disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.32774 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.11477 Alcohol use disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.524 NCI-H1299 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K62650632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02905 NCOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68926 meninx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.096632 juvenile TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.753297 PMC4657121__F1 PFOCR Pathway Figure Associations 2023 1.0 null decisionmaking GeneRIF Biological Term Annotations 1.0 null spike TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.327896 RPS21 Pathway Commons Protein-Protein Interactions 1.0 null DYRK1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48869 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.96865 CUTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00712 nuclear chromosome part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063933 depressive disorder, major GAD Gene-Disease Associations 1.0 null rostral interstitial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20956 PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.774004 CCDC136 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53744 reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.22454 Prefrontal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.135 CTDSPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93333 MFHAS1 Pathway Commons Protein-Protein Interactions 1.0 null Preoptic area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.567 rhythmic process GO Biological Process Annotations 2015 1.0 null GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3344 EDARADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95107 BRD-K74114857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00183 Potocki-Shaffer syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nipple TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.689 GTEX-UPJH-0926-SM-4IHKA GTEx Tissue Sample Gene Expression Profiles 1.0 1.56804 Arcuate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.786 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.38821 mantle zone of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07433 carotid body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.516891 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.282 neversmokers GeneRIF Biological Term Annotations 1.0 null Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.087 aai GeneRIF Biological Term Annotations 1.0 null TRMT44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72621 Benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.356 BRD-K61796560 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66831 CASP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13087 GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33016 SW1783 CCLE Cell Line Gene Expression Profiles -1.0 -3.25044 Telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.332 soft tissue HPA Tissue Protein Expression Profiles -1.0 -2.69367 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cuticle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.515 GTEX-NPJ8-0526-SM-3MJHN GTEx Tissue Sample Gene Expression Profiles 1.0 0.977059 EMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2395 Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11839199-CPR-58-e13746-s001.docx-2-CEBPA_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null PMC5479833__F4 PFOCR Pathway Figure Associations 2024 1.0 null postpartum GeneRIF Biological Term Annotations 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TMEM69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57438 transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.134341 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02278 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 1.40035 Placenta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.388 HT-115 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.471 KIAA2026 Pathway Commons Protein-Protein Interactions 1.0 null Hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.185 thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076224 dendritic GeneRIF Biological Term Annotations 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7564 Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.984 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null interstitial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245491 serotonin GeneRIF Biological Term Annotations 1.0 null Carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ABCD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09711 16611997-Table2 GeneSigDB Published Gene Signatures 1.0 null normal GeneRIF Biological Term Annotations 1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7433 Diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.523 PMC8440935__F4 PFOCR Pathway Figure Associations 2024 1.0 null DAPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43076 GTEX-S4Q7-0826-SM-4AD5E GTEx Tissue Sample Gene Expression Profiles 1.0 1.2442 GSE152050,GSE152052_1_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE60217_1_v_9_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null PML Pathway Commons Protein-Protein Interactions 1.0 null relief GeneRIF Biological Term Annotations 1.0 null muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.338177 decreased cardiac output MGI Mouse Phenotype Associations 2023 1.0 null Perturb_10327_KO_Anxa1_SRP377197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.49435 Heterochromatin domain COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.005 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01111 controlled GeneRIF Biological Term Annotations 1.0 null Learning disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.022 Varicosity COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.292 BCS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86374 towards GeneRIF Biological Term Annotations 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RORA_RORA Rummagene Transcription Factor Associations 2026 1.0 null Aryl hydrocarbon receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.812 MFE280 DepMap CRISPR Gene Dependency 1.0 3.33828 BRD-K62698674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21369 polymorphisms GeneRIF Biological Term Annotations 1.0 null artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.682287 BRD-K67390061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.59146 GTEX-UJMC-0626-SM-4IHJQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.5587 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975028 mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077315 IFI35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4339 CRCGN017_MCF10A.TP53.M_24H:L22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.22019 GTEX-S7SE-0526-SM-2XCD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19773 Bronchopulmonary Dysplasia DisGeNET Gene-Disease Associations 1.0 null phobic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.217352 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.373 Memory Disorders CTD Gene-Disease Associations 1.0 1.49045 ZNF586 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K32718856 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.98042 PATU8988T CCLE Cell Line Gene Expression Profiles -1.0 -1.73449 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21552 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.417718 PMC12748338-12672_2025_4052_MOESM1_ESM.docx-0-SIX3_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_HEPG2_48H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.97794 fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.256902 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076642 central GeneRIF Biological Term Annotations 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6826 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3174 BRD-K35560933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08558 superficial stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25821 SCC25 CCLE Cell Line Gene Expression Profiles -1.0 -1.74488 neuron part GO Cellular Component Annotations 2015 1.0 null BRD-K22093396 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.52062 small intestine neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.470332 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82146 pallor MGI Mouse Phenotype Associations 2023 1.0 null r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02217 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01655 PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43343 Migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.662 croup DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.370737 correlates GeneRIF Biological Term Annotations 1.0 null LS1034 DepMap CRISPR Gene Dependency 1.0 2.52023 GIPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77349 contribute GeneRIF Biological Term Annotations 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null XYLT1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null recurrent hypersomnia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.505356 Cervical ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.755 ARGLU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17048 PMC2936065__F2 PFOCR Pathway Figure Associations 2023 1.0 null centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28389 mucoepidermoid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.17896 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8273 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33156 HDAC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81461 Rhabdomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.678 GTEX-W5X1-0006-SM-3GIJZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08384 Leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.857889 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_HEPG2_48H:J23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.44811 GSE178532_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.838025 ZNF84 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46727 excess GeneRIF Biological Term Annotations 1.0 null TNR Pathway Commons Protein-Protein Interactions 1.0 null interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31965 aromatic amino acid family metabolic process GO Biological Process Annotations 2015 1.0 null GSE146253_0_v_2_stat4_mouse RummaGEO Gene Perturbation Signatures 1.0 null bowel GeneRIF Biological Term Annotations 1.0 null CRCGN015_MCF10A.WT.HP_24H:P22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.11525 NDOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70715 SDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2366 ARL4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56362 BRD-K45609222 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09842 Alcohol-Related Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null whipple disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.23492 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048058 Middle temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.546 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Enteroendocrine cell_Undefined_Mouse CellMarker Gene-Cell Type Associations 1.0 null Gut cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.641 MCM4 Pathway Commons Protein-Protein Interactions 1.0 null Neuroblastoma DisGeNET Gene-Disease Associations 1.0 null GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980321 retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.776079 ca-77 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.580818 LHX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57866 BRD-K53893978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.89557 Nicotine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.719 UNCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.03863 Posterior cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 GTEX-S4Q7-0626-SM-4AD5M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846197 GFPT1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73837 transporter GeneRIF Biological Term Annotations 1.0 null cholinergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.231206 BRD-K27656392 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00706 MARCKS LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00601221 abuse GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -0.873603 Arterial smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.394 Sudden infant death syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.202 carotid artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.164218 intestinal benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.134003 rosiglitazone_mus musculus_gpl1261_gds3798 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MCF2L2 Pathway Commons Protein-Protein Interactions 1.0 null cerebral peduncle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.210525 fatal familial insomnia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.623751 Nasal polyp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.602 GSE226285_3_v_1_nr0b1_human RummaGEO Gene Perturbation Signatures 1.0 null abnormal skin appearance MPO Gene-Phenotype Associations 1.0 null lesch-nyhan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.460506 Colonic mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.952 decreased cardiac muscle contractility MGI Mouse Phenotype Associations 2023 1.0 null BZW2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74832 GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59806 autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048566 BRD-K14470344 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90272 BRD-K02420839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60163 GTEX-XUW1-0726-SM-4BOP5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01483 fetus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.279659 hsa-miR-1293 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Interanteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93843 HDGFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30705 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.26545 BON-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.041 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31259 CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null basophilic leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.17336 strongest GeneRIF Biological Term Annotations 1.0 null GTEX-PLZ5-1126-SM-3P613 GTEx Tissue Sample Gene Expression Profiles 1.0 0.856529 CCNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56578 KLHDC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75304 Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13442 GTEX-X4XX-0011-R2A-SM-3P623 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.941062 Learning Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null NCI-H1155 GDSC Cell Line Gene Expression Profiles 1.0 1.74645 TRAK1 Pathway Commons Protein-Protein Interactions 1.0 null hypersensitivity reaction type ii disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.366301 GJB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0433 depression GAD Gene-Disease Associations 1.0 null decreased cardiac output MPO Gene-Phenotype Associations 1.0 null perikaryon COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.783698 CRCGN009_HEPG2_24H:H02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.50293 physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.079026 Movement disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.326 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.27268 SEMA3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90969 APLNR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06341 DNAJC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97685 PEX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.18664 TM2D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5064 enteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.702717 ANAPC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78599 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5268 PMC8000752__F1 PFOCR Pathway Figure Associations 2023 1.0 null abnormal heart rate MPO Gene-Phenotype Associations 1.0 null dopaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.776909 GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13507 hippocampus (hippocampal formation)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22906 GTEX-OXRO-0011-R10A-SM-2I5EH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04721 CCAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31643 NUDT9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41492 DRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24981 hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.241546 developing GeneRIF Biological Term Annotations 1.0 null Aromatic amino acid hydroxylase, iron/copper binding site InterPro Predicted Protein Domain Annotations 1.0 null GTEX-OHPK-1826-SM-2YUMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.252 SOHLH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77081 phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06631 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65214 waist GeneRIF Biological Term Annotations 1.0 null predictor GeneRIF Biological Term Annotations 1.0 null GTEX-P4QT-0626-SM-3NMCP GTEx Tissue Sample Gene Expression Profiles 1.0 1.11162 GTEX-R53T-0926-SM-3GADH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09657 PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55992 GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910885 Follicular dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.924 Gait Disorders, Neurologic HuGE Navigator Gene-Phenotype Associations 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null CHST15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03008 PPP2CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07474 cellular amine metabolic process GO Biological Process Annotations 2015 1.0 null SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910212 PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR Rummagene Transcription Factor Associations 2026 1.0 null TRABD2A Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLXNB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47818 PMC6829839-13578_2019_352_MOESM3_ESM.xlsx-Table_3-SRG_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null NRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94459 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.688291 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.905235 ZFP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14807 GTEX-S341-2026-SM-2XCAA GTEx Tissue Sample Gene Expression Profiles 1.0 1.01946 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.128154 EXOSC1 Pathway Commons Protein-Protein Interactions 1.0 null RUNDC3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50954 RT11284 CCLE Cell Line Gene Expression Profiles -1.0 -2.6731 endogenous GeneRIF Biological Term Annotations 1.0 null ZFHX3 Pathway Commons Protein-Protein Interactions 1.0 null liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11674 YWHAH Pathway Commons Protein-Protein Interactions 1.0 null BRD-K36997940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03545 GNET cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.937 GTEX-XPT6-0326-SM-4B66V GTEx Tissue Sample Gene Expression Profiles 1.0 1.31442 Intestinal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.753 MLLT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91003 TC205 DepMap CRISPR Gene Dependency 1.0 3.1631 GTEX-SSA3-0426-SM-32QPI GTEx Tissue Sample Gene Expression Profiles 1.0 1.38276 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null MIXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31527 GATA1_G1E-ER4_mm9_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-K1-A3PO-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE159148_0_v_1_sdc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.474 Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.829 biosynthesis Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842612 BRD-K33912919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95431 learning GeneRIF Biological Term Annotations 1.0 null ARSI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42989 PHYH LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00431576 Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFDN2 Pathway Commons Protein-Protein Interactions 1.0 null GRAMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66803 Dorsal raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.345 ZBTB8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2294 GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07527 GSE136238_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 G cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.313 Circumventricular organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.292 PDCD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00549 Ventral striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.281 inflammation GeneRIF Biological Term Annotations 1.0 null BRD-K40361885 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.92827 Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28298 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.16179 impulsive inpatients GAD Gene-Disease Associations 1.0 null Morbid obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 stacking GeneRIF Biological Term Annotations 1.0 null drug dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.096697 Superior cervical ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.725 KNS-62 GDSC Cell Line Gene Expression Profiles -1.0 -1.83654 Exocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.81 GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886798 Dentate gyrus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71857 Impulsive Aggression DisGeNET Gene-Disease Associations 1.0 null adddiction GeneRIF Biological Term Annotations 1.0 null hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.31784 BRD-K89584810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0552 ZNF486 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05519 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.16867 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.07781 CJM CCLE Cell Line Gene CNV Profiles 1.0 1.45715 Recognition HuGE Navigator Gene-Phenotype Associations 1.0 null anxiety disorder; depression GAD Gene-Disease Associations 1.0 null Body wall muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.728 Liver Cirrhosis HuGE Navigator Gene-Phenotype Associations 1.0 null FOSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99949 PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70443 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90458 CRCGN009_HEPG2_24H:L01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.34962 RASSF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01859 proteasome regulatory particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.351382 PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO Molecular Function Annotations 2015 1.0 null RIC8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88613 HT CCLE Cell Line Gene Mutation Profiles 1.0 null laryngeal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213291 BRD-K17122222 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11245 GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878522 GTEX-R53T-1326-SM-48FCQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.865034 Functional gastric disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.451 Perturb_17721_KO_Mbnl1_SRP014709 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.194 Germinal center TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.392 Nicotine Dependence DisGeNET Gene-Disease Associations 1.0 null GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.86774 Major Affective Disorder DisGeNET Gene-Disease Associations 1.0 null hsa-miR-320d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SMC6 Pathway Commons Protein-Protein Interactions 1.0 null Chromaffin cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.882 CCM2L Pathway Commons Protein-Protein Interactions 1.0 null GSE155305_2_v_0_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null UPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12466 Cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.073 GTEX-Q2AH-0526-SM-2I3ED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42282 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58799 BRD-K93923246 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19019 PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-397-SIX3_AS1_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XV7Q-0526-SM-4BRWR GTEx Tissue Sample Gene Expression Profiles 1.0 2.06807 GSE216043_10_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.84 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.39294 Middle frontal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.596 PMC4147234__F1 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-XBED-1426-SM-4AT4G GTEx Tissue Sample Gene Expression Profiles 1.0 1.21857 RPS6KA3 KEA Substrates of Kinases 1.0 null CARHSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15493 nervosa GeneRIF Biological Term Annotations 1.0 null membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.507977 GSE149870_0_v_1_pfn1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MDAMB134VI CCLE Cell Line Gene Expression Profiles 1.0 1.36933 DENND3 Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TELOTRISTAT ETHYL DGIdb Drug Targets 2026 1.0 6.6165 GTEX-T5JC-0326-SM-4DM5C GTEx Tissue Sample Gene Expression Profiles 1.0 1.71448 MAMDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3081 GTEX-WFG7-1526-SM-4LVMG GTEx Tissue Sample Gene Expression Profiles 1.0 0.963634 PMC2841835__F1 PFOCR Pathway Figure Associations 2023 1.0 null GATA1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stomach HPA Tissue Gene Expression Profiles 1.0 1.13708 Infralimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.627 Bile duct carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 strictly GeneRIF Biological Term Annotations 1.0 null CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XUZC-0626-SM-4BOPG GTEx Tissue Sample Gene Expression Profiles 1.0 1.42548 Tail muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.6 BRD-K52101275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.82193 Agoraphobia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.498 KIF12 Pathway Commons Protein-Protein Interactions 1.0 null esophagus_5b HPA Tissue Sample Gene Expression Profiles -1.0 -1.49614 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67199 CACO-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.388 women GeneRIF Biological Term Annotations 1.0 null NCI-H2170 COSMIC Cell Line Gene Mutation Profiles 1.0 null LIG3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00504387 SUCLG2 Pathway Commons Protein-Protein Interactions 1.0 null hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.738271 EOMES-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null tmd GeneRIF Biological Term Annotations 1.0 null dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.425514 hsa-miR-4435 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 RAB7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52072 Pneumonia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 GATA1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null opiate dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.134957 MHC class Ib protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.715 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null family GeneRIF Biological Term Annotations 1.0 null COMMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37789 LPAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12184 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75266 NUDT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80163 GTEX-Q734-0126-SM-48U1E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06174 Colonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.6 Metabolic dysfunction-associated steatotic liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.543 Peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.057 DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 GSE199204,GSE211619_4_v_3_glutamine_human RummaGEO Drug Perturbation Signatures 1.0 null CBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08332 RIMS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30722 496100402_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.45496 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.906915 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.401 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42153 Superior colliculus, motor related, intermediate gray layer, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29376 ATP2C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63439 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00047 Stomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.9 epithelioma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.33761 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832364 primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.938958 oxoacid metabolic process GO Biological Process Annotations 2015 1.0 null liminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.58844 SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24632 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1301 carriers GeneRIF Biological Term Annotations 1.0 null GTEX-S4P3-0326-SM-4AD6P GTEx Tissue Sample Gene Expression Profiles 1.0 2.66559 cellular nitrogen compound biosynthetic process GO Biological Process Annotations 2015 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55463 either GeneRIF Biological Term Annotations 1.0 null hsa-miR-4478 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.822 indole-containing compound biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K09250647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.65602 Kna TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.25 overall GeneRIF Biological Term Annotations 1.0 null SPRY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52003 UBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25092 r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11112 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG Rummagene Transcription Factor Associations 2026 1.0 null cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.25601 Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2891 Chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.298 CRCGN015_HEPG2_48H:L04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.95929 GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846114 BTN3A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58781 GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10577 NCIH1155 CCLE Cell Line Gene Expression Profiles 1.0 1.36863 Limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.376 Gastroesophageal reflux disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.199 schizophrenia GAD Gene-Disease Associations 1.0 null Myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 Dentate gyrus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59638 Amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.111 HIRA Pathway Commons Protein-Protein Interactions 1.0 null PMC8123408__F2 PFOCR Pathway Figure Associations 2024 1.0 null PYROXD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55629 IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null Body wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.452 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE156708_1_v_2_fbxo11_human RummaGEO Gene Perturbation Signatures 1.0 null KMT2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96052 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.178403 BRD-K41492504 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.78086 HDHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1754 Cholinergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.737 HADHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2757 YT COSMIC Cell Line Gene Mutation Profiles 1.0 null since GeneRIF Biological Term Annotations 1.0 null hsa-miR-4263 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.590839 regardless GeneRIF Biological Term Annotations 1.0 null Triple Negative Breast Neoplasms DisGeNET Gene-Disease Associations 1.0 null STC-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.631 BRD-K59185421 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.53732 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877181 drofenine-2714 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null C19orf81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22936 BRD-K36282114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30167 revealed GeneRIF Biological Term Annotations 1.0 null ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50364 citalopram GAD Gene-Disease Associations 1.0 null Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.259 NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -2.27927 Adrenal gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.164 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.96092 4a-Carbinolamine tetrahydrobiopterin MW Enzyme Metabolite Associations 1.0 null GSE44157,GSE44163_3_v_0_nr6a1_mouse RummaGEO Gene Perturbation Signatures 1.0 null variant GeneRIF Biological Term Annotations 1.0 null evaluation GeneRIF Biological Term Annotations 1.0 null Irritable Bowel Syndrome DisGeNET Gene-Disease Associations 1.0 null Synovia TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 CCNC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55228 liver HPA Tissue Gene Expression Profiles -1.0 -0.844224 GSE244072_10_v_9_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.309 H2BK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10285 superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48926 RFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92393 Gut wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.511 Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null 496100591_TCx_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26345 Larval brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 GTEX-OHPK-0426-SM-3MJH3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73577 ICC3 DepMap CRISPR Gene Dependency 1.0 3.43676 GSE150669_0_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC8511346__F1 PFOCR Pathway Figure Associations 2024 1.0 null PMC8705244__F2 PFOCR Pathway Figure Associations 2024 1.0 null ANLN Pathway Commons Protein-Protein Interactions 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10363 malignant glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.078841 Coelomocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.208 preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10042 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4751 MYSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15671 hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53882 PMC3422784__F5 PFOCR Pathway Figure Associations 2023 1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48039 temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.58437 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Tight junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.037 TSTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59125 BRD-K44834268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52616 Endocrine cell_Undefined_Human CellMarker Gene-Cell Type Associations 1.0 null medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19054 early myoclonic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.656837 GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null Hyperglycemia CTD Gene-Disease Associations 1.0 1.34314 cholera DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.170544 deficiency GeneRIF Biological Term Annotations 1.0 null TEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70206 Nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.722 denatured GeneRIF Biological Term Annotations 1.0 null H2AFZ Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18222 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856503 lingual gyrus, left, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.852504 Jejunal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.519 monooxygenase activity GO Molecular Function Annotations 2015 1.0 null PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51567 anger GeneRIF Biological Term Annotations 1.0 null Antisocial personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.508 GTEX-OIZG-0426-SM-3LK5W GTEx Tissue Sample Gene Expression Profiles 1.0 1.42401 periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5163 Cholangiocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.76 NCI-H2452 GDSC Cell Line Gene Expression Profiles -1.0 -1.5732 Neuroendocrine tumor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.307 pivotal GeneRIF Biological Term Annotations 1.0 null lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.165217 cell-cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.023 impact GeneRIF Biological Term Annotations 1.0 null 4a-Hydroxytetrahydrobiopterin HMDB Metabolites of Enzymes 1.0 null ZNF502 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69919 GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.4212 CRCGN015_MCF10A.TP53.M_24H:F21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2088 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.09645 isthmic vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11915 BRD-K24877937 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58521 hsa-miR-323-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 p1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.48935 LIPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0767 BRD-K71339292 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08118 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.13778 brain Phosphosite Textmining Biological Term Annotations 1.0 null Pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.125 COMMD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15643 GTEX-QDT8-1026-SM-43V6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.2113 PMC6829839-13578_2019_352_MOESM4_ESM.xlsx-Table_4-SRG_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null small intestine HPA Tissue Protein Expression Profiles 1.0 1.6514 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.46764 Sleep disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.709 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25789 remains GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null former GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74251 interleukin-23 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.478 htr1a GeneRIF Biological Term Annotations 1.0 null FOXA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRAP1 Pathway Commons Protein-Protein Interactions 1.0 null glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307167 placeboinduced GeneRIF Biological Term Annotations 1.0 null artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.068491 anion binding GO Molecular Function Annotations 2015 1.0 null GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19772 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.45112 RRP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58443 ATP5O Pathway Commons Protein-Protein Interactions 1.0 null Perturb_6637_KO_SATB1_ERP024525 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38417 prenatal exposure delayed effects GAD Gene-Disease Associations 1.0 null Celiac disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.828 binds GeneRIF Biological Term Annotations 1.0 null ZZEF1 Pathway Commons Protein-Protein Interactions 1.0 null pulmonary artery smooth muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.625061 OS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06578 Oxitriptan HMDB Metabolites of Enzymes 1.0 null colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360782 atoms GeneRIF Biological Term Annotations 1.0 null MTHFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89327 USP27X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62236 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.859258 GTEX-XV7Q-0226-SM-4BRVL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32414 primary amino compound metabolic process GO Biological Process Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28176 Pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.615 anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79421 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67066 MAP3K5 Pathway Commons Protein-Protein Interactions 1.0 null Plasma membrane signaling receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.065 resembles GeneRIF Biological Term Annotations 1.0 null Pancreatic beta cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.098 C6orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46656 ETV3 Pathway Commons Protein-Protein Interactions 1.0 null Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3333 CCNQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80697 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858448 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4137 BRD-A97437073_Rosiglitazone_PC3_6.0_h_80.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RBM39 Pathway Commons Protein-Protein Interactions 1.0 null NR1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78131 granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73362 transition metal ion binding GO Molecular Function Annotations 2015 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.1692 mitral valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.411283 Pulmonary artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.615 Syncytiotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.286 Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.674 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75353 hsa-miR-942 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11652 PMC2936065__F2 PFOCR Pathway Figure Associations 2024 1.0 null Hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.222 NUGC3 CCLE Cell Line Gene Expression Profiles 1.0 1.75029 HT29 BioGPS Cell Line Gene Expression Profiles 1.0 1.63533 Substance Withdrawal Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null susceptible GeneRIF Biological Term Annotations 1.0 null BCL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77914 PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT Rummagene Transcription Factor Associations 2026 1.0 null pancreas HPA Tissue Gene Expression Profiles -1.0 -1.59157 ZBTB43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74757 BRD-K59045095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02805 spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.11686 Steatotic liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.797 blood vessel GTEx Tissue Gene Expression Profiles 1.0 1.45652 ZNF764 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26413 RN-46A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216528 three GeneRIF Biological Term Annotations 1.0 null OVTOKO COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-V955-2626-SM-3NM9F GTEx Tissue Sample Gene Expression Profiles 1.0 1.15183 Myelencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.41 substantial GeneRIF Biological Term Annotations 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Adolescent Idiopathic Scoliosis DisGeNET Gene-Disease Associations 1.0 null TM7SF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76279 BRD-K01668149 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59243 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91023 BRD-K66311249 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58009 BRD-K97410356 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.25941 Heroin Dependence HuGE Navigator Gene-Phenotype Associations 1.0 null PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA Rummagene Transcription Factor Associations 2026 1.0 null Personality Tests HuGE Navigator Gene-Phenotype Associations 1.0 null Rad51C-XRCC3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 BMPR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71505 SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3201 ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12832 Cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.299 Biofilm matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.967 ACADM_KO_GDS4546_512_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Breast Neoplasms CTD Gene-Disease Associations 1.0 1.30574 Inner mucus layer COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.881 GTEX-OIZF-1526-SM-3MJGY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889341 EIF4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49434 neuroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.749166 MAP3K4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00733369 TRIM52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00067 Perturb_8954_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 inhibition GeneRIF Biological Term Annotations 1.0 null region GeneRIF Biological Term Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15634 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.4965 trigeminal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.639619 Arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.979 SMPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69444 lung HPA Tissue Protein Expression Profiles -1.0 -0.873603 Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43399 4-aminobutyrate transaminase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.511 FKBP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11627 DEDD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67255 COR-L88 GDSC Cell Line Gene Expression Profiles 1.0 1.7137 GMEB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12045 CHAF1B Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05759 site GeneRIF Biological Term Annotations 1.0 null Diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.301 panic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.07908 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32117 Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16534_KO_Cdk8/Cdk19_SRP351257 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0422 BRD-K20203758 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15601 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94528 PMC3422784__F5 PFOCR Pathway Figure Associations 2024 1.0 null Conceptus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.14 nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Atopic dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.39489 SFT2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06281 Substance abuse DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.896 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.339 bodyweight GeneRIF Biological Term Annotations 1.0 null Avoidance Learning HuGE Navigator Gene-Phenotype Associations 1.0 null GYS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81237 GTEX-OXRL-0426-SM-3NM97 GTEx Tissue Sample Gene Expression Profiles 1.0 1.6747 Perturb_3286_KO_E8I_SRP144318 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.11478 phenol-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null COPG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65601 lt94 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.632 influence GeneRIF Biological Term Annotations 1.0 null GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40262 PPP2CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5025 DNAJB12 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K44722555 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37974 GSE211126_1_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BRD-K69918256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33824 PMC11102563-41531_2024_715_MOESM1_ESM.pdf-81-MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03606 Bulimia Nervosa DisGeNET Gene-Disease Associations 1.0 null suicidal GeneRIF Biological Term Annotations 1.0 null Tryptophan metabolism KEGG Pathways 2026 1.0 null tear gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.179245 ABHD17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4919 BRD-K93726930 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08036 BMP receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.818 EBF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53906 Psychiatric Status Rating Scales HuGE Navigator Gene-Phenotype Associations 1.0 null vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.550186 communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.765535 Juvenile TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.98 BRD-K43610632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53503 Acute Myeloid Leukemia_LAML_TCGA-AB-2838-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null form GeneRIF Biological Term Annotations 1.0 null Enteric nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.514 NEMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.52002 ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20399 smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.354084 BRD-K41700289 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.50576 while GeneRIF Biological Term Annotations 1.0 null DCANP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13289 GTEX-U3ZM-0326-SM-4DXUJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.62889 neuron projection GO Cellular Component Annotations 2023 1.0 null mental depression DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.14208 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HJ-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null alcohol abuse GAD Gene-Disease Associations 1.0 null TOPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45249 respective GeneRIF Biological Term Annotations 1.0 null NTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79227 MLF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86597 CCRT CEM BioGPS Cell Line Gene Expression Profiles 1.0 0.883088 Tripartite ATP-independent periplasmic transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.593 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8489 TUBB6 Pathway Commons Protein-Protein Interactions 1.0 null COA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0397 Dentate gyrus, granule cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53498 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 ATG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1162 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null serotonin metabolic process GO Biological Process Annotations 2023 1.0 null cellular biogenic amine biosynthetic process GO Biological Process Annotations 2015 1.0 null ect GeneRIF Biological Term Annotations 1.0 null AGRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25206 ZNF541 Pathway Commons Protein-Protein Interactions 1.0 null fibromyalgia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.386308 P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null completed GeneRIF Biological Term Annotations 1.0 null BRD-K66590796 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58262 Synaptic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.84 Perturb_8939_Mut_RB1_SRP220467 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Intestinal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.649 Subiculum, ventral part, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54692 rna polymerase ii transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.452427 responding GeneRIF Biological Term Annotations 1.0 null Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16329 GSE173873_5_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null FAF2 Pathway Commons Protein-Protein Interactions 1.0 null mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.03589 subtypes GeneRIF Biological Term Annotations 1.0 null umbilical cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.105442 BRD-K80185984 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2794 insulin resistance GWASdb SNP-Phenotype Associations 1.0 0.436665 GSK3B Pathway Commons Protein-Protein Interactions 1.0 null Epithalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.441 Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06044 positive regulation of biological process GO Biological Process Annotations 2015 1.0 null paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52225 Multiple sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.68 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null KYSE270 CCLE Cell Line Gene Expression Profiles -1.0 -2.17637 Perturb_15233_KO_Nm1_SRP212300 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.9087 GSE232631_0_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.60877 RBMX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40668 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.905235 evidence GeneRIF Biological Term Annotations 1.0 null GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854885 placenta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080457 CRCGN015_HEPG2_48H:G04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.46687 Lung Neoplasms CTD Gene-Disease Associations 1.0 1.60337 GTEX-SJXC-0426-SM-2XCFH GTEx Tissue Sample Gene Expression Profiles 1.0 1.1408 unipolar GeneRIF Biological Term Annotations 1.0 null ZC3H7B Pathway Commons Protein-Protein Interactions 1.0 null brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.04209 specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.930414 PMC9204954__F2 PFOCR Pathway Figure Associations 2024 1.0 null LIPC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00594152 RPS16 Pathway Commons Protein-Protein Interactions 1.0 null Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.276 Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.416 gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046082 TMEM267 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32634 midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles 1.0 1.30745 Bae TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.055 Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 BRD-K35520972 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55298 Tyrosine 3-monooxygenase-like InterPro Predicted Protein Domain Annotations 1.0 null Dopaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.905 Neuroendocrine tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.99 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.86775 impaired GeneRIF Biological Term Annotations 1.0 null Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.678 CRCGN015_HEPG2_48H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.09266 bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09581 Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.658 Dystonia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 Reserpine CTD Gene-Chemical Interactions 1.0 null megakaryoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178538 CD8_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.942998 NCI-H720 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mitochondrial outer membrane translocase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.51 FAM110C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00903 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13665 Cor pulmonale DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79421 Mucous cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.843 GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07602 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.926905 PHF20L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40485 enzyme GeneRIF Biological Term Annotations 1.0 null NCIH2029 CCLE Cell Line Gene Expression Profiles 1.0 1.84966 Pulmonary hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.931 Fibre tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.957 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.431 CRCGN015_HEPG2_48H:M17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.33134 FOXA1-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36256 Type 1 diabetes mellitus_T lymphocyte_GSE10586 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.26856 BRD-K07152092 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.91009 BRD-K39639513 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25386 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042646 SLC9A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94512 factors GeneRIF Biological Term Annotations 1.0 null BRD-K49207204 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87887 Metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.093 polymorphism GeneRIF Biological Term Annotations 1.0 null GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Drug Habituation DisGeNET Gene-Phenotype Associations 1.0 null BRD-K88934376 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0841 further GeneRIF Biological Term Annotations 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 breast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.511778 ACTC1 Pathway Commons Protein-Protein Interactions 1.0 null B4GALT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74072 variants GeneRIF Biological Term Annotations 1.0 null GTEX-Q734-1426-SM-48TZQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857326 HIST1H2BM Pathway Commons Protein-Protein Interactions 1.0 null PMC9172632-pnas.2107006119.sd01.xlsx-Gene_sets_for_zscores-MITF_targets_Cheli_et_al_2009_Human_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XYKS-0426-SM-4BRW4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24065 Impulsive Character (Finding) DisGeNET Gene-Phenotype Associations 1.0 null GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 suprachiasmatic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59124 RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.959444 Phenylketonuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.86 LRRC8D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43495 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.57595 SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K01795516 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.52872 WIPF1 Pathway Commons Protein-Protein Interactions 1.0 null T-bar COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.559 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.169672 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null aging GeneRIF Biological Term Annotations 1.0 null OLIG2 ChEA Transcription Factor Targets 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRD-K86586698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5785 PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87216 snp GeneRIF Biological Term Annotations 1.0 null Oppositional defiant disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 Cecal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 Substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.144 strong GeneRIF Biological Term Annotations 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.275 Candidiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.247 HSC3 CCLE Cell Line Gene CNV Profiles 1.0 1.59678 GSE119978,GSE180930_0_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE145628,GSE145629_1_v_0_myrf_human RummaGEO Gene Perturbation Signatures -1.0 null biomarker GeneRIF Biological Term Annotations 1.0 null increase GeneRIF Biological Term Annotations 1.0 null Distal tip cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 Familial thyroid dyshormonogenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 caudate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.978482 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58701 ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7106 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Memory, Long-Term HuGE Navigator Gene-Phenotype Associations 1.0 null BRD-K27109474 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59802 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 4.04113 theoretical GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.973416 PRDM10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39232 GSE165122_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Dysthymic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 BRD-K06318195 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35425 Nerve ring TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.085 Panic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.874 Attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.244 nucleus of the lateral olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02217 Proventriculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 GABA-ergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.085 GSE169571_3_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Gastrointestinal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293 ZNF236 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29257 GSE173873_12_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null endophenotypes GeneRIF Biological Term Annotations 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null FENCLONINE DGIdb Drug Targets 2026 1.0 0.827062 enlarged heart MGI Mouse Phenotype Associations 2023 1.0 null intolerance GeneRIF Biological Term Annotations 1.0 null GSE160083,GSE160084_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null diathesis GeneRIF Biological Term Annotations 1.0 null QPCTL Pathway Commons Protein-Protein Interactions 1.0 null Synovial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.011 psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.47286 Ileum smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.573 GSE226285_3_v_1_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null leads GeneRIF Biological Term Annotations 1.0 null shows GeneRIF Biological Term Annotations 1.0 null Polygenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 BRD-K68608492 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39729 points GeneRIF Biological Term Annotations 1.0 null genetic GeneRIF Biological Term Annotations 1.0 null DDR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00068 DPH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44535 MSTN_KO_GDS3637_439_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.96145 Tryptophan metabolism(Homo sapiens) WikiPathways Pathways 2014 1.0 null TMEM37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34728 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.02879 metabolic process GO Biological Process Annotations 2015 1.0 null amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35437 bone remodeling disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.302337 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 ZNF799 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87542 cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17502 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.12 multiple carboxylase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.251015 discriminating GeneRIF Biological Term Annotations 1.0 null LTB4R2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00656888 SGK3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00391701 GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.04537 PMC3425429__F1 PFOCR Pathway Figure Associations 2024 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8958 neuron projection GO Cellular Component Annotations 2025 1.0 null orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964936 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38613 TRIP13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60481 brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.26852 SFXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99654 raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.67023 PRDX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54056 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70678 spleen HPA Tissue Protein Expression Profiles 1.0 0.896756 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73163 BRD-K68008192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.06515 GTEX-QV31-0326-SM-447BM GTEx Tissue Sample Gene Expression Profiles 1.0 1.42432 Meconium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.809 I-cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.931 AP1M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18684 esophagus HPA Tissue Gene Expression Profiles -1.0 -0.940229 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.86062 prion disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.175411 magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.1427 Anterior lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.211 Ileus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.211 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.138 Pharyngeal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.758 respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.223509 BRD-K73227539 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51026 Stress Disorders, Post-Traumatic HuGE Navigator Gene-Phenotype Associations 1.0 null DNAH8 Pathway Commons Protein-Protein Interactions 1.0 null oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen GO Molecular Function Annotations 2015 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JOSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00043 Psychopharmacology HuGE Navigator Gene-Phenotype Associations 1.0 null Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.431 ChIP_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K22481359 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.11766 regulated exocytosis GO Biological Process Annotations 2023 1.0 null stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.212271 Gastric corpus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.983 TSPYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39278 GSE103068_0_v_4_volasertib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC11711664-41598_2025_85366_MOESM6_ESM.xlsx-AA-METABOLIC_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null RBM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05498 ZNF485 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86183 epithelial cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CRCGN016_MCF10A.TP53.M_24H:G06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.11709 primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.897448 irritable bowel syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.5304 Leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.29 Gestational diabetes DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.68 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03117 APTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87012 decision GeneRIF Biological Term Annotations 1.0 null slc6a4 GeneRIF Biological Term Annotations 1.0 null TARDBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60271 BRD-K42392619 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92578 Outer mitochondrial membrane protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.407 PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6 Rummagene Transcription Factor Associations 2026 1.0 null Dyskinesia, Drug-Induced HuGE Navigator Gene-Phenotype Associations 1.0 null MTOR_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null Cerebral giant cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.919 STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80056 DIRAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30832 GTEX-NFK9-0526-SM-2YUNL GTEx Tissue Sample Gene Expression Profiles 1.0 0.898821 mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Ion channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.328 HSPB1 Pathway Commons Protein-Protein Interactions 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null MOGGUVW DepMap CRISPR Gene Dependency 1.0 2.9603 QGP1 CCLE Cell Line Gene Expression Profiles 1.0 3.4075 GTEX-WFJO-0926-SM-4LVM2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.827401 PMC5571864__F1 PFOCR Pathway Figure Associations 2023 1.0 null APH1B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00504225 Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.9 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75757 GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K60937893 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.73983 indole-containing compound biosynthetic process GO Biological Process Annotations 2025 1.0 null BRD-K37527074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.45363 aetiology GeneRIF Biological Term Annotations 1.0 null ACT domain InterPro Predicted Protein Domain Annotations 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01434 neurotransmitter Phosphosite Textmining Biological Term Annotations 1.0 null MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2524 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926524 mediodorsal nucleus of thalamus_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62143 BRD-K22193148 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0272 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.7555 EZH2 ENCODE Transcription Factor Targets 1.0 null antigen Phosphosite Textmining Biological Term Annotations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04852 TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5902 PMC6032036__F4 PFOCR Pathway Figure Associations 2023 1.0 null individuals GeneRIF Biological Term Annotations 1.0 null trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.530298 SECISBP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48157 USP34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90361 practice GeneRIF Biological Term Annotations 1.0 null p-815 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.746689 Ileal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.193 GTEX-OOBJ-0426-SM-3NB1S GTEx Tissue Sample Gene Expression Profiles 1.0 1.36039 lymphoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052906 GTEX-REY6-1126-SM-48FDU GTEx Tissue Sample Gene Expression Profiles 1.0 1.21965 ZNF74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31935 496100672_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33247 Metabolism Reactome Pathways 2024 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.6514 GART CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54296 PMC6032036__F4 PFOCR Pathway Figure Associations 2024 1.0 null DCAKD LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00628738 Urine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.8 Gastric corpus mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.539 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08964 Photoreceptor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.469 integument phenotype MPO Gene-Phenotype Associations 1.0 null Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33611 developmental process GO Biological Process Annotations 2015 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.612152 Nephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 Cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.0603 b19 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.565 PAIP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39378 Small intestine mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.67 Cholangiocarcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.572 smoking GeneRIF Biological Term Annotations 1.0 null Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.267 mammary gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.535833 abnormal respiratory function MPO Gene-Phenotype Associations 1.0 null Nucleus solitarius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 Small intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.487 RPH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39503 core mediator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.452427 COLO-684 GDSC Cell Line Gene Expression Profiles 1.0 1.9898 Labyrinthine zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.633 regulation of cell differentiation GO Biological Process Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lactose intolerance DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 AHRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96819 GTEX-XXEK-0926-SM-4BRWH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07567 BRD-K35469110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56041 Platelet dense granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.492 autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.783526 Borderline Personality Disorder DisGeNET Gene-Disease Associations 1.0 null Secretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.105 APOBEC3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38724 GSE193177_1_v_3_st266_mouse RummaGEO Drug Perturbation Signatures 1.0 null deficit GeneRIF Biological Term Annotations 1.0 null ZNF846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5185 DENND10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9445 neurofilament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.264215 BRD-K13839731 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58523 Idiopathic Pulmonary Arterial Hypertension DisGeNET Gene-Disease Associations 1.0 null serotonin and melatonin biosynthesis HumanCyc Pathways 1.0 null BRD-K23405268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05211 posteroventral (inferior) parietal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968107 furegrelate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50618 Myoepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.765 umbilical artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.436438 alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.429642 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38476 Tic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 UBTF Pathway Commons Protein-Protein Interactions 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 rs7997012 GeneRIF Biological Term Annotations 1.0 null cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.76024 TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ADHD and autism ASD pathways WikiPathways Pathways 2024 1.0 null CALCOCO2 Pathway Commons Protein-Protein Interactions 1.0 null GSE103068_5_v_4_volasertib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-MXD1_MXD1 Rummagene Transcription Factor Associations 2026 1.0 null pulmonary hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.60342 Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.08 POU4F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.38693 Teeth hard tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -2.20965 glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.289386 cellular amino acid metabolic process GO Biological Process Annotations 2015 1.0 null brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.920344 tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.51571 GPR161 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60607 PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3 Rummagene Transcription Factor Associations 2026 1.0 null Nucleus of Darkschewitsch Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.91275 lymphoid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.13431 GSE135030_8_v_9_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Mesentery TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.4 GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Villus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.965 GSE149880_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K92431275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06136 GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.898854 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58668 borderline personality disorder GAD Gene-Disease Associations 1.0 null KCNF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4698 H3118 DepMap CRISPR Gene Dependency 1.0 6.34784 dna-directed rna polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.431041 FAM117B Pathway Commons Protein-Protein Interactions 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.882238 a779c GeneRIF Biological Term Annotations 1.0 null GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2093 reticular formation of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09477 Cholangiocarcinoma DisGeNET Gene-Disease Associations 1.0 null CRCGN015_HEPG2_48H:H19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.07304 BRD-K79213964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24899 BRD-K82791632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47695 TCCPAN2 CCLE Cell Line Gene Mutation Profiles 1.0 null Hemorrhage CTD Gene-Disease Associations 1.0 1.02559 fatigue MGI Mouse Phenotype Associations 2023 1.0 null acetylcholine-gated channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.806 CRCGN017_MCF10A.WT.HP_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.19125 PMC10338540-41416_2023_2282_MOESM2_ESM.xlsx-AA_metabolism-Gene_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null other GeneRIF Biological Term Annotations 1.0 null Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.41 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null Verbal Learning HuGE Navigator Gene-Phenotype Associations 1.0 null Blood coagulation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 Presynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.408 intestinal GeneRIF Biological Term Annotations 1.0 null bulimic GeneRIF Biological Term Annotations 1.0 null CACHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8053 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993905 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.791 PMC6372777__F2 PFOCR Pathway Figure Associations 2024 1.0 null GSE63857_3_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXA1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NPC1L1 Pathway Commons Protein-Protein Interactions 1.0 null pleiotropic GeneRIF Biological Term Annotations 1.0 null colonrectum_c HPA Tissue Sample Gene Expression Profiles 1.0 1.60689 Hyperplasia CTD Gene-Disease Associations 1.0 1.31237 Signal Transduction Reactome Pathways 2024 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3613-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Optic lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.265 GTEX-RNOR-0426-SM-2TF4U GTEx Tissue Sample Gene Expression Profiles 1.0 0.842387 Tryptophan metabolism WikiPathways Pathways 2024 1.0 null ERAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14922 Gastric ulcer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 MY-M12 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_HEPG2_48H:L01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.79283 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48926 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92113 Foregut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.346777 GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles 1.0 1.02011 BRD-K57228212 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68735 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 0.939643 Perturb_3417_KO_Cdx2_SRP093647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19038 BRD-K54420800 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.63008 GSE124694_0_v_1_arid1a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bipolar I disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 Rumen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.934 luteolin-3041 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02691 BRD-K37280550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67623 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null oxygen GeneRIF Biological Term Annotations 1.0 null lymphoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060359 ELFN1 Pathway Commons Protein-Protein Interactions 1.0 null Pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.981 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.68104 5-Hydroxy-L-tryptophan HMDB Metabolites of Enzymes 1.0 null Inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.454 GTEX-QCQG-1526-SM-48U25 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07333 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null rs6295 GeneRIF Biological Term Annotations 1.0 null BRD-K96987864 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11869 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04255 DPH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94262 positive regulation of cell differentiation GO Biological Process Annotations 2015 1.0 null primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.831482 Blood platelet disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 TMEM138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18894 Blood platelet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.219 Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.916176 nucleus solitarius TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.327164 klatskin's tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.249257 Lateral geniculate body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 hyperactivity GeneRIF Biological Term Annotations 1.0 null BRD-K37961770 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14265 BRD-K88448214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41994 HDLM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.47418 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.05993 heightened GeneRIF Biological Term Annotations 1.0 null GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49968 FAM83D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54705 BRD-A01717918 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22624 GSE134923_1_v_0_ncor1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221989 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11113 BRD-K68361061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15146 nicotine; personality trait GAD Gene-Disease Associations 1.0 null KIRREL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98426 endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.219047 Fascicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.174881 Crohn's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.993 BRD-K43901257 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.08315 mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50427 Edema CTD Gene-Disease Associations 1.0 1.35473 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.900365 symptomatologiy GeneRIF Biological Term Annotations 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28233 Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null PODXL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94225 KOPN-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K56759808 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18321 Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1697 GSE183413_0_v_2_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null MYO19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40012 TRIM23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.36486 Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 Cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.983 CRCGN016_MCF10A.TP53.M_24H:F14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.34172 RFX5 ENCODE Transcription Factor Targets 1.0 null Ovarian cumulus cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.962 FABP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90457 AP1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55878 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01581 risk GeneRIF Biological Term Annotations 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35773 tryptophan GeneRIF Biological Term Annotations 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.832719 NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -0.954683 ion binding GO Molecular Function Annotations 2015 1.0 null RAB21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83252 Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.707 Lumbar spine TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.853 gastroparesis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.379626 microcephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.246098 probands GeneRIF Biological Term Annotations 1.0 null GTEX-U4B1-1926-SM-3DB9E GTEx Tissue Sample Gene Expression Profiles 1.0 1.42374 small intestine HPA Tissue Gene Expression Profiles 1.0 0.83185 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.18393 FAM200B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00582462 CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RIMS2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles 1.0 1.27673 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMCO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70044 ATP5C1 Pathway Commons Protein-Protein Interactions 1.0 null PABPC1L2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88186 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.38893 Learning Disorders CTD Gene-Disease Associations 1.0 1.17497 traits GeneRIF Biological Term Annotations 1.0 null ZNF317 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5879 northern GeneRIF Biological Term Annotations 1.0 null striatonigral degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.503824 CD4_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.947136 CSMD2 Pathway Commons Protein-Protein Interactions 1.0 null Pain Perception HuGE Navigator Gene-Phenotype Associations 1.0 null undifferentiated GeneRIF Biological Term Annotations 1.0 null gastrointestinal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221521 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 KIAA0922 Pathway Commons Protein-Protein Interactions 1.0 null GSE173873_8_v_3_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null appears GeneRIF Biological Term Annotations 1.0 null Nucleus of the lateral olfactory tract, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14034 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02252 Perturb_15688_KO_Rel_SRP075924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.67751 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969105 SRF-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MFAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30664 COA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34234 Soft body part TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.468 GSE188870,GSE188871_4_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21893 RWDD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11247 Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.273 GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945772 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K64748422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06417 CRLF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68542 PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null BLTP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40252 Aster COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.824 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.719524 Bed nuclei of the stria terminalis, anterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4172 GTEX-R53T-1126-SM-48FD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07528 Arsenic CTD Gene-Chemical Interactions 1.0 null EPHA7 MSigDB Cancer Gene Co-expression Modules 1.0 null constitute GeneRIF Biological Term Annotations 1.0 null Autoimmune disease of skin and connective tissue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.399 migraine GeneRIF Biological Term Annotations 1.0 null axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.988782 GSE60217_1_v_0_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.732265 PMC3517648__F7 PFOCR Pathway Figure Associations 2023 1.0 null Neurotransmitter disorders WikiPathways Pathways 2024 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.1 GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19722 suicide GAD Gene-Disease Associations 1.0 null TMEM199 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68251 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.34229 FEM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62015 Temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.02 CRCGN016_MCF10A.WT.HP_24H:K20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.43095 Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38153 groups GeneRIF Biological Term Annotations 1.0 null skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.637999 GTEX-S4Z8-0526-SM-4AD4T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965137 BRD-K28320832 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08934 assessed GeneRIF Biological Term Annotations 1.0 null syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.1798 RCBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33828 ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7102 Perturb_6636_KO_SATB1_ERP024525 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 sample GeneRIF Biological Term Annotations 1.0 null nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.18586 CRCGN016_MCF10A.TP53.M_24H:H10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.64205 Enteroendocrine cell_Ileum_Human CellMarker Gene-Cell Type Associations 1.0 null GSE165122_0_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042094 regulatory GeneRIF Biological Term Annotations 1.0 null GTEX-WFJO-1126-SM-4LVLZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11067 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.366671 among GeneRIF Biological Term Annotations 1.0 null ventrolateral prefrontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.79421 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.82356 Pain agnosia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 PPP2R3B Pathway Commons Protein-Protein Interactions 1.0 null Neurotransmitter receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.413 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.893698 thyroid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.088965 Cortical cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.612 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42794 METTL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44323 ERP44 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null other GAD High Level Gene-Disease Associations 1.0 0.300704 RPS24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02775 Subiculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07301 related GeneRIF Biological Term Annotations 1.0 null Precancerous Conditions CTD Gene-Disease Associations 1.0 1.44817 ARG1 Pathway Commons Protein-Protein Interactions 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 1.6514 post-traumatic stress disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.747 abnormal behavior MPO Gene-Phenotype Associations 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 GTEX-UPK5-1526-SM-4JBJA GTEx Tissue Sample Gene Expression Profiles 1.0 1.71742 predicted GeneRIF Biological Term Annotations 1.0 null Neuroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.087 Synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.454 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.7 BRD-K72314068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.61284 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.18368 electroclinical syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.159838 SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TBC1D25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76973 LRAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39744 GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844657 GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.92318 Synovial tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.612 DDX24 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974083 BRD-K85802892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27916 BEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38724 hence GeneRIF Biological Term Annotations 1.0 null oxidoreductase activity GO Molecular Function Annotations 2015 1.0 null BRD-K00920341 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38521 GTEX-O5YV-1026-SM-3LK72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951418 diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.95356 BRD-K47895166 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.23956 FTC-133 GDSC Cell Line Gene Expression Profiles -1.0 -1.56912 BRD-K32235162 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27841 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 2.3342 White blood cell count GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.81549 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20324 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4513 KMS27 CCLE Cell Line Gene CNV Profiles 1.0 1.38223 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.663149 adrenal cortex disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.250311 GTEX-QCQG-1626-SM-48U26 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26769 GTEX-UTHO-1026-SM-3GAF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987656 Somatoform Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null Synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.41 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K36468214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45916 Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.66385 Sjogren's syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 dopamine GeneRIF Biological Term Annotations 1.0 null Cytoplasmic side of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.978 occipital lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.365633 ascl1 GeneRIF Biological Term Annotations 1.0 null Parasitic helminthiasis infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.415 Serotonin CTD Gene-Chemical Interactions 1.0 null fatigue MPO Gene-Phenotype Associations 1.0 null medullary carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.184946 intermittent explosive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.750457 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Pineocytoma DisGeNET Gene-Disease Associations 1.0 null GSE173873_12_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null FZD10 Pathway Commons Protein-Protein Interactions 1.0 null GSE231745_1_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null SGSM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65701 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56424 Arterial endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.936 PMC11903305-41586_2024_8507_MOESM3_ESM.xlsx-Table_S1_MAF-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.997 throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235457 TGFBR2_knockout_294_GSE36778 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.7902 COQ10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42607 Lymphnode BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.867128 KRAS.600_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null Rge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.604 BHY CCLE Cell Line Gene CNV Profiles 1.0 1.46067 small molecule metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03771 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03023 A3KAW CCLE Cell Line Gene Expression Profiles 1.0 1.3762 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tendency GeneRIF Biological Term Annotations 1.0 null RPRD2 Pathway Commons Protein-Protein Interactions 1.0 null oliva TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.447576 mRNA_DPPA5A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null apud cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.395331 BRD-K32535831 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6126 PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.14033 VAPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3698 GDF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86365 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12267 BRD-K22449045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5514 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94528 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.0641 temporal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69987 NCOR1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U8T8-0426-SM-3DB8X GTEx Tissue Sample Gene Expression Profiles 1.0 0.850476 GTEX-S4UY-1626-SM-4AD55 GTEx Tissue Sample Gene Expression Profiles 1.0 0.875505 POU3F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02798 ARID4B Pathway Commons Protein-Protein Interactions 1.0 null predicting GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5497-01A-02R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Somatoform Disorder DisGeNET Gene-Disease Associations 1.0 null MLXIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41687 BRD-K19142902 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31794 bmi GeneRIF Biological Term Annotations 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -1.02585 GTEX-XV7Q-0005-SM-4BRWI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05707 hydroxylasea218c GeneRIF Biological Term Annotations 1.0 null MAGI1 Pathway Commons Protein-Protein Interactions 1.0 null ocular motility disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.089064 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null magnocellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08868 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.949866 posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28176 BRD-K73500518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01434 LCN12 Pathway Commons Protein-Protein Interactions 1.0 null PLEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44204 BRD-K86073842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18941 PMC3425429__F1 PFOCR Pathway Figure Associations 2023 1.0 null plastid-encoded plastid rna polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.504724 interacts GeneRIF Biological Term Annotations 1.0 null Anus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.251 several GeneRIF Biological Term Annotations 1.0 null CNOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88225 Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null antisocial personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.863046 optic lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34334 Epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.681 BRD-K29684372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19865 GSE60217_1_v_10_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null Arterial endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 Helper T-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.849 TUFM Pathway Commons Protein-Protein Interactions 1.0 null caudate putamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.685959 PPP1R18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66802 PYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02779 Secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.836 ACACA Pathway Commons Protein-Protein Interactions 1.0 null Ileocecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.241 ARIH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58828 Superior frontal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.774 major GeneRIF Biological Term Annotations 1.0 null octreotide LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04768 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nor GeneRIF Biological Term Annotations 1.0 null ZNF211 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38419 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906341 Constipation HuGE Navigator Gene-Phenotype Associations 1.0 null preisthmic midbrain tectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42698 NOLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87705 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47288 GTEX-VUSG-0526-SM-4KL22 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73048 nicotine GeneRIF Biological Term Annotations 1.0 null PPARD_KO_GDS4320_619_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null amino acid binding GO Molecular Function Annotations 2015 1.0 null SAMD9L Pathway Commons Protein-Protein Interactions 1.0 null GSE188870,GSE188871_1_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null BRD-A98888138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16539 RAG1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.946033 GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828186 information GeneRIF Biological Term Annotations 1.0 null BRD-K97617600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.53199 ENTPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2592 localized GeneRIF Biological Term Annotations 1.0 null DNAJB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99789 korean GeneRIF Biological Term Annotations 1.0 null SIRT1_KO_GSE28790_47_mouse_brain (3 mo) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DHPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57021 myelencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.2198 PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.949544 TNPO1 Pathway Commons Protein-Protein Interactions 1.0 null single-organism metabolic process GO Biological Process Annotations 2015 1.0 null Prenatal Exposure Delayed Effects HuGE Navigator Gene-Phenotype Associations 1.0 null ATOSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20235 Viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.646 fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.992379 r7 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15854 disturbed GeneRIF Biological Term Annotations 1.0 null biosynthetic process GO Biological Process Annotations 2015 1.0 null MRGBP Pathway Commons Protein-Protein Interactions 1.0 null PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null pineal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 BRD-K49391713 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15956 posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00253 Paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.407 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null QSOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39351 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70689 locus GeneRIF Biological Term Annotations 1.0 null GTEX-V955-0926-SM-4JBJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.21937 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.095924 relevant GeneRIF Biological Term Annotations 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -2.24113 Ammonium Chloride CTD Gene-Chemical Interactions 1.0 null GTEX-XXEK-0008-SM-4BRW7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.921548 TMEM175 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92331 GTEX-S32W-0426-SM-4AD6H GTEx Tissue Sample Gene Expression Profiles 1.0 2.16325 CENPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29852 musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.662784 abnormal heart ventricle pressure MPO Gene-Phenotype Associations 1.0 null capacity GeneRIF Biological Term Annotations 1.0 null middle temporal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.87208 ZNF703 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945696 GTEX-WWYW-1326-SM-3NB2S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25196 Chronic pulmonary heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.13012 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.855298 hl60 HPA Cell Line Gene Expression Profiles 1.0 2.05217 organic cyclic compound biosynthetic process GO Biological Process Annotations 2015 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.57082 Adult Pineoblastoma DisGeNET Gene-Disease Associations 1.0 null EPB41L4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09882 cerebellum GeneRIF Biological Term Annotations 1.0 null CECR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9119 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54434 basomedial amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52289 failure GeneRIF Biological Term Annotations 1.0 null DNAJC28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66688 NAV3 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CX-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HT144SKINFV2 DepMap CRISPR Gene Dependency 1.0 2.73517 aminohippuric acid-3076 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CACNG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50749 BRD-K04147413 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29956 WIL2-NS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.614 Dense core granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.868 PGPEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48326 BRD-K96431636 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11613 NAA38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80978 Glutamate decarboxylase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.981 CORL95 CCLE Cell Line Gene Expression Profiles 1.0 1.79973 positive regulation of fat cell differentiation GO Biological Process Annotations 2015 1.0 null GTEX-NPJ8-1926-SM-3MJGB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908782 FST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53297 a218c GeneRIF Biological Term Annotations 1.0 null REXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01927 pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.176389 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9516 Neuronal cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.539 3-amino-1-methyl-5H-pyrido(4,3-b)indole CTD Gene-Chemical Interactions 1.0 null ACTR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31349 hypotropia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.709572 GTEX-XXEK-0726-SM-4BRWF GTEx Tissue Sample Gene Expression Profiles 1.0 1.63793 Lewy body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.952 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.06065 Postoperative Nausea And Vomiting DisGeNET Gene-Phenotype Associations 1.0 null Extrinsic component of cytoplasmic side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.959 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.43 PRRC2A Pathway Commons Protein-Protein Interactions 1.0 null NCI-H716 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.83 AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83015 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null egr1 GeneRIF Biological Term Annotations 1.0 null Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.897 PMC12176927-125_2025_6424_MOESM1_ESM.pdf-2-RFX3_RFX3 Rummagene Transcription Factor Associations 2026 1.0 null personality GAD Gene-Disease Associations 1.0 null Neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.384 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.963896 PRAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11753 ZNF331 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41013 extracellular region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.550599 carboxylic acid binding GO Molecular Function Annotations 2015 1.0 null BRD-K90644597 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30136 including GeneRIF Biological Term Annotations 1.0 null ZNF264 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08064 GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20447 mesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073995 superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41395 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Addison's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.003 BRD-K43979194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04737 GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PDHA2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-P4PQ-0426-SM-3NMCI GTEx Tissue Sample Gene Expression Profiles 1.0 1.82291 Colon descendens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.299 IgA immunoglobulin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.676 ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71627 hsa-miR-320c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.022 habit GeneRIF Biological Term Annotations 1.0 null lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60067 GSE173873_5_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null L-Tryptophan HMDB Metabolites of Enzymes 1.0 null GTEX-RUSQ-0326-SM-47JWS GTEx Tissue Sample Gene Expression Profiles 1.0 1.23506 YAF2 Pathway Commons Protein-Protein Interactions 1.0 null GJD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34505 BRD-K47052171 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40926 BRD-K74245698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01101 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.46826 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860215 GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.027 GTEX-OOBJ-1826-SM-3NB1C GTEx Tissue Sample Gene Expression Profiles 1.0 1.52114 t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.5822 Human - Fetal Development - L2 - Intestine-Chromaffin cells HuBMAP Azimuth Cell Type Annotations 1.0 null SW780 CCLE Cell Line Gene CNV Profiles -1.0 -1.35541 GTEX-S7PM-0426-SM-3NM91 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44306 TMPRSS11A Pathway Commons Protein-Protein Interactions 1.0 null temperamental GeneRIF Biological Term Annotations 1.0 null a549 HPA Cell Line Gene Expression Profiles -1.0 -0.926903 MTRF1 Pathway Commons Protein-Protein Interactions 1.0 null MET_knockout_248_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.73467 GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898549 colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.597263 MFSD2A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00473307 alcohol GeneRIF Biological Term Annotations 1.0 null CRCGN016_MCF10A.WT.HP_24H:A18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.1294 mainly GeneRIF Biological Term Annotations 1.0 null basic GeneRIF Biological Term Annotations 1.0 null organic substance biosynthetic process GO Biological Process Annotations 2015 1.0 null hsa-miR-3934 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GATA2 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045917 Tear gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.857 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null t47d HPA Cell Line Gene Expression Profiles -1.0 -2.39936 differences GeneRIF Biological Term Annotations 1.0 null Nephridium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.583 Proteinuria CTD Gene-Disease Associations 1.0 1.24024 purified GeneRIF Biological Term Annotations 1.0 null Osteoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.634 rectum HPA Tissue Gene Expression Profiles 1.0 1.32811 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPIRE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38714 SNU-C1 GDSC Cell Line Gene Expression Profiles -1.0 -1.87368 MPV17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51393 HAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56782 homozygote GeneRIF Biological Term Annotations 1.0 null ZNF280D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.27392 GTEX-S4Q7-0726-SM-4AD5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.06164 BRD-A63503250 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59376 xray GeneRIF Biological Term Annotations 1.0 null PMC7986977__F5 PFOCR Pathway Figure Associations 2023 1.0 null Hypoglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.225 Hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.022 Crfk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.762 CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amitriptyline-5453 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7077 CDCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0772 Medial geniculate body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.932 GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles 1.0 0.85426 COLO704 CCLE Cell Line Gene Expression Profiles 1.0 2.65493 smokers GeneRIF Biological Term Annotations 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.21922 rostral ventrolateral medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31332 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4408 anorexia nervosa; bulimia GAD Gene-Disease Associations 1.0 null serotonin metabolic process GO Biological Process Annotations 2015 1.0 null slc6a45httlpr GeneRIF Biological Term Annotations 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.45 GABA receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.218 pancreas_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.26633 urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053265 PMC5591914__F1 PFOCR Pathway Figure Associations 2023 1.0 null WDR89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19429 UROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72663 Acute Depression DisGeNET Gene-Disease Associations 1.0 null NCIH2286 CCLE Cell Line Gene CNV Profiles 1.0 1.36066 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 0.895779 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06142 PKM Pathway Commons Protein-Protein Interactions 1.0 null BRD-K56738235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40318 Fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.014 SLC35F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74933 PECAPJ34CLONEC12 CCLE Cell Line Gene Expression Profiles -1.0 -1.80409 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50515 Depression, Postpartum HuGE Navigator Gene-Phenotype Associations 1.0 null Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.987 CNOT4 Pathway Commons Protein-Protein Interactions 1.0 null DACT1 Pathway Commons Protein-Protein Interactions 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10363 Axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.043 WARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18806 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.95829 RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 HLA-B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65045 Amyotrophic lateral sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.236 BRD-K53291208 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02063 DAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53379 SKIC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.79275 PSMB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64333 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54481 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.162417 BRD-K54053991 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39489 rhombomere 7 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07807 GATA1_G1E-ER4_mm9_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNAJC30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84704 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.834 KASUMI2 CCLE Cell Line Gene Expression Profiles 1.0 1.71564 pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.03819 PRG4 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bipolar Disorder DisGeNET Gene-Disease Associations 1.0 null U118MG DepMap CRISPR Gene Dependency 1.0 2.15942 CRCGN008_HEPG2_24H:C24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3711 DCC MSigDB Cancer Gene Co-expression Modules 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14697 AP4B1 Pathway Commons Protein-Protein Interactions 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7215 Obstructive lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 OGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3092 FAAH2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00620381 Extravillous cytotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 Bulimia DisGeNET Gene-Disease Associations 1.0 null GTEX-NFK9-0008-SM-4E3JE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998621 FOXC2 Pathway Commons Protein-Protein Interactions 1.0 null abnormal skin morphology MPO Gene-Phenotype Associations 1.0 null RHOBTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68236 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null temperament GeneRIF Biological Term Annotations 1.0 null POLDIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10398 biotinidase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.353027 SH3RF1 Pathway Commons Protein-Protein Interactions 1.0 null selfreport GeneRIF Biological Term Annotations 1.0 null BRD-K96077293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7273 PTPRU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63834 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50047 HSD17B4 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_1431_KO_Prmt7_SRP362551 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.36365 abnormal heart size MPO Gene-Phenotype Associations 1.0 null PREX2 Pathway Commons Protein-Protein Interactions 1.0 null CRCGN014_HEPG2_24H:F21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.75657 postmortem GeneRIF Biological Term Annotations 1.0 null photoreceptor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.396844 ARID5B Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-548u TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17717 Plasma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.545 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00673 XKRX Pathway Commons Protein-Protein Interactions 1.0 null GLIPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87641 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 COMMD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57829 PAFAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82456 GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles 1.0 1.01061 LGALS7B Pathway Commons Protein-Protein Interactions 1.0 null tryptophan 5-monooxygenase activity GO Molecular Function Annotations 2023 1.0 null HEC251 CCLE Cell Line Gene Mutation Profiles 1.0 null GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1686 Autoimmune disease of central nervous system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.709 BRD-K49635910 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18127 primary amino compound biosynthetic process GO Biological Process Annotations 2023 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 1.5558 especially GeneRIF Biological Term Annotations 1.0 null DIP2B Pathway Commons Protein-Protein Interactions 1.0 null PMC5571864__F1 PFOCR Pathway Figure Associations 2024 1.0 null ACACA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27565 KANK2 Pathway Commons Protein-Protein Interactions 1.0 null PMC6372777__F2 PFOCR Pathway Figure Associations 2023 1.0 null ADAM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24819 4a-Hydroxytetrahydrobiopterin MW Enzyme Metabolite Associations 1.0 null Neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.998 possibly GeneRIF Biological Term Annotations 1.0 null H3F3A Pathway Commons Protein-Protein Interactions 1.0 null Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.596 GTEX-QXCU-0226-SM-2TC5W GTEx Tissue Sample Gene Expression Profiles 1.0 1.4272 hsa-miR-194 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 cytosol GO Cellular Component Annotations 2015 1.0 null GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68823 Aptitude HuGE Navigator Gene-Phenotype Associations 1.0 null Gut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.396 autonomic nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.458373 CRCGN015_HEPG2_48H:B11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.48631 doubling GeneRIF Biological Term Annotations 1.0 null hsa-miR-4419b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 KLHDC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33418 tm903 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.519 children GeneRIF Biological Term Annotations 1.0 null Bone Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null Borderline personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.97 LX1031 DrugBank Drug Targets 1.0 null SHANK2 Pathway Commons Protein-Protein Interactions 1.0 null BRD-A38066207 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16196 breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161523 Antropyloric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.398 influences GeneRIF Biological Term Annotations 1.0 null BRD-K42654859 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48106 basal ganglia disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.911845 LN18 BioGPS Cell Line Gene Expression Profiles -1.0 -0.907697 cerebral palsy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.139332 KIF20B Pathway Commons Protein-Protein Interactions 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.1664 Anteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76825 personality GeneRIF Biological Term Annotations 1.0 null parathyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.130422 PGD Pathway Commons Protein-Protein Interactions 1.0 null taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.562042 Hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.081 GTEX-PSDG-1026-SM-48TCV GTEx Tissue Sample Gene Expression Profiles 1.0 1.44852 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18954 CFAP410 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96454 Huntington's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.353 neuronal GeneRIF Biological Term Annotations 1.0 null cerebrospinal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.747102 mesomere 2 (preisthmus or caudal midbrain) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5003 MINDY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.9639 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31475 DPM1 Pathway Commons Protein-Protein Interactions 1.0 null TENM2 Pathway Commons Protein-Protein Interactions 1.0 null TMEM18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26186 Brain endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.617 iron ion binding GO Molecular Function Annotations 2015 1.0 null mantle zone of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04238 Colorectal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.52 CCC5 DepMap CRISPR Gene Dependency 1.0 2.71224 Opportunistic mycosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 enteroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.412771 Fatty Liver CTD Gene-Disease Associations 1.0 1.27813 arterial endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298883 mechanisms GeneRIF Biological Term Annotations 1.0 null medullary thyroid carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.190022 YWHAZ Hub Proteins Protein-Protein Interactions 1.0 null TAF2 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of DTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26301 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17849 HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92223 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 2.1106 axis GeneRIF Biological Term Annotations 1.0 null parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.061818 design GeneRIF Biological Term Annotations 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.61014 DPY19L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22615 UNC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39924 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Triple-Negative Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null rs1800532 GeneRIF Biological Term Annotations 1.0 null KAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83845 BRD-K73831546 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00702 SKOV3 BioGPS Cell Line Gene Expression Profiles 1.0 0.846861 mammary epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.284253 MYO18A Pathway Commons Protein-Protein Interactions 1.0 null salivary gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.113607 population GeneRIF Biological Term Annotations 1.0 null toxic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.08202 Raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.819 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54966 TTC39C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75009 Respiratory allergy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.165 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.913933 BRD-K18084996 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21282 GSE200352_11_v_6_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null r4 part of medial paralemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26565 GTEX-V1D1-0326-SM-4JBIY GTEx Tissue Sample Gene Expression Profiles 1.0 1.72236 increases GeneRIF Biological Term Annotations 1.0 null GTEX-XPVG-2926-SM-4B66G GTEx Tissue Sample Gene Expression Profiles 1.0 0.972546 CRCGN016_MCF10A.TP53.M_24H:P14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.30319 Heroin dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.068 persistent fetal circulation syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.226952 breast epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289582 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures 1.0 null thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.346409 Ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.183 FOXA2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K73706189 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33585 GSE152432_1_v_2_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null skin HPA Tissue Protein Expression Profiles -1.0 -1.87776 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.02092 LC1SQ DepMap CRISPR Gene Dependency 1.0 2.4662 Stem-cell-derived-endothelial cell_Undefined_Human CellMarker Gene-Cell Type Associations 1.0 null orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.60327 perception GeneRIF Biological Term Annotations 1.0 null abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.178864 SRF ChEA Transcription Factor Targets 1.0 null Larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.91 SYNJ2BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35357 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.899 Jejunum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.94 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null depression GeneRIF Biological Term Annotations 1.0 null GPR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25459 GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00658 ILF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21798 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.65475 HPN LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00552848 GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03319 Osteoporosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.845 Rectal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.24 PBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61513 MARVELD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50759 PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-MXD1_MXD1 Rummagene Transcription Factor Associations 2026 1.0 null Blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.369 PRKACA Pathway Commons Protein-Protein Interactions 1.0 null STX16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0023 SFT2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83546 ENSG00000286190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0636 FYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25731 lateral amygdaloid nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.351114 Gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.649 Tremor DisGeNET Gene-Phenotype Associations 1.0 null BRD-K91766181 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86234 BRD-K77892726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84336 where GeneRIF Biological Term Annotations 1.0 null residue GeneRIF Biological Term Annotations 1.0 null NCI H226 BioGPS Cell Line Gene Expression Profiles 1.0 0.843586 GTEX-P78B-1826-SM-3P5YX GTEx Tissue Sample Gene Expression Profiles 1.0 0.943473 scalp TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.503926 GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34515 GTEX-P4QS-0426-SM-3NMCQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.70834 PURA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18786 TCL1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35353 Puberty, Precocious HuGE Navigator Gene-Phenotype Associations 1.0 null ZFP91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64534 Bronchial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.553 GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 1.14021 present GeneRIF Biological Term Annotations 1.0 null serotonin biosynthetic process GO Biological Process Annotations 2025 1.0 null cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.636723 Alzheimer Disease HuGE Navigator Gene-Phenotype Associations 1.0 null 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01996 CEP170 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64579 JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 3.2741 CBX2 ENCODE Transcription Factor Targets 1.0 null DDT1-MF-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.568 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45963 mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.986294 Leaf sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.515 heterocycle biosynthetic process GO Biological Process Annotations 2015 1.0 null arm GeneRIF Biological Term Annotations 1.0 null hsa-miR-3187-3p TargetScan 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1.0 3.46545 Rheumatoid arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.901 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Osteogenic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.703 BRD-K58432332 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37982 SERPING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20142 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6359 Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2564 ARL8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53148 NECAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11286 DMRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6467 tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.427765 ERBB2IP Pathway Commons Protein-Protein Interactions 1.0 null BRD-K33734659 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09629 Prelimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.505 NR4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57559 FBLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21975 ABITRAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36638 PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null PLOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53387 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4237 GOLGA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94169 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null GSE148066,GSE157787_9_v_6_n4bp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null UBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66564 AGK Pathway Commons Protein-Protein Interactions 1.0 null thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.494918 ATP2B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62347 acacetin-2189 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.70803 organic acid binding GO Molecular Function Annotations 2015 1.0 null nuclear transcription factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.452427 lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31877 CAL72 DepMap CRISPR Gene Dependency 1.0 5.11005 LUZP1 Pathway Commons Protein-Protein Interactions 1.0 null CDS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64375 S100A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30582 Autoimmune disease of exocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 SERF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5669 Anxiety Disorders HuGE Navigator Gene-Phenotype Associations 1.0 null Seasonal affective disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.157 STRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57663 BRD-K73608149 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37702 BRD-K74039237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20334 PMC11462941-CAS-115-2947-s001.pdf-138-CHAMP1_CHAMP1 Rummagene Transcription Factor Associations 2026 1.0 null CHDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68716 HCE4 DepMap CRISPR Gene Dependency 1.0 3.36721 Prelimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30276 Perturb_3339_KO_Cns4_SRP310440 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.48547 clinically GeneRIF Biological Term Annotations 1.0 null Medial geniculate nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.524 altretamine-3090 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Interferon regulatory factor 5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.552 Eyespot apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.219 TAF9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71826 homicidal GeneRIF Biological Term Annotations 1.0 null carboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null PMC4496795-srep12063-s2.xls-STAT1_subnetwork-Gene_symbol_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null GDE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78109 CRCGN015_HEPG2_48H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 9.6812 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.05993 abnormal cardiovascular system morphology MPO Gene-Phenotype Associations 1.0 null SIRT1_Deficiency_GDS4895_316_mouse_Brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SHE Pathway Commons Protein-Protein Interactions 1.0 null persistent GeneRIF Biological Term Annotations 1.0 null lack GeneRIF Biological Term Annotations 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null Integrin alphaIIb-beta3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.807 Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33618 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048552 RODATRISTAT DGIdb Drug Targets 2026 1.0 1.65412 hydroxylase GeneRIF Biological Term Annotations 1.0 null Gut mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.641 regulation of developmental process GO Biological Process Annotations 2015 1.0 null PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null pretectal region Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19702 Neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.463 Bone structure disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.423 GTEX-NL4W-0011-R2a-SM-2I5GV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08306 ACIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91029 Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084468 RBFOX2 Pathway Commons Protein-Protein Interactions 1.0 null PTOV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82067 primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.18368 Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K79324911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46202 neostriatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.43107 CAMK1B Kinase Library Serine Threonine Kinome Atlas 1.0 null 496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28671 N-nitrosomorpholine CTD Gene-Chemical Interactions 1.0 null localization GeneRIF Biological Term Annotations 1.0 null GSE232631_5_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null LCORL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23731 BRD-K48069820 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16479 central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.101 gut wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.564833 cytosol COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 EIF2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59208 gain GeneRIF Biological Term Annotations 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20977 vacuole-isolation membrane contact site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.107 SUDHL4 CCLE Cell Line Gene Expression Profiles 1.0 1.40843 FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.939433 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null atomicresolution GeneRIF Biological Term Annotations 1.0 null orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.98186 GTEX-WFG8-1626-SM-4LVMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.02612 GTEX-WYJK-0426-SM-3NM9G GTEx Tissue Sample Gene Expression Profiles 1.0 0.844696 dorsal raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.46457 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23064 harderian gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.314046 Motor neuron disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.221 Urinary Bladder Neoplasms CTD Gene-Disease Associations 1.0 1.28919 Diarrhea HuGE Navigator Gene-Phenotype Associations 1.0 null H3C13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42201 AP1S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20651 degree GeneRIF Biological Term Annotations 1.0 null endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.314278 Lymphoid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.195 Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32797 SIDS Susceptibility Pathways(Mus musculus) WikiPathways Pathways 2014 1.0 null lives GeneRIF Biological Term Annotations 1.0 null diffrent GeneRIF Biological Term Annotations 1.0 null Serotonin and melatonin biosynthesis Reactome Pathways 2014 1.0 null CAMK1D Kinase Library Serine Threonine Kinome Atlas 1.0 null substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.179 MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 1.14688 hsa-miR-4668-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28752 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22237 Circular smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.902 UNKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38826 serotonin biosynthetic process GO Biological Process Annotations 2023 1.0 null CDV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48622 FOXA1 ENCODE Transcription Factor Targets 1.0 null epilepsy syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.362609 pancreatic GeneRIF Biological Term Annotations 1.0 null lymphoblastic leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.071362 COMPOUND 23A [PMID: 33417443] DGIdb Drug Targets 2026 1.0 3.30825 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MAFK_MAFK Rummagene Transcription Factor Associations 2026 1.0 null CRCGN011_HEPG2_24H:H10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.25295 Mast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.047 NR4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91856 attentiondeficithyperactivity GeneRIF Biological Term Annotations 1.0 null GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12845 TUBB3 Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.71 Chromosome Aberrations HuGE Navigator Gene-Phenotype Associations 1.0 null TPRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19783 hsa-miR-3121-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 BRD-K02793474 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59886 reduced GeneRIF Biological Term Annotations 1.0 null age GeneRIF Biological Term Annotations 1.0 null dependence GeneRIF Biological Term Annotations 1.0 null Major Depression, Single Episode DisGeNET Gene-Disease Associations 1.0 null GTEX-U4B1-1026-SM-4DXT1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24975 FRMD6 Pathway Commons Protein-Protein Interactions 1.0 null Self Mutilation HuGE Navigator Gene-Phenotype Associations 1.0 null MED12L Pathway Commons Protein-Protein Interactions 1.0 null r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34458 PMC7986977__F5 PFOCR Pathway Figure Associations 2024 1.0 null IPMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28509 phenol-containing compound biosynthetic process GO Biological Process Annotations 2015 1.0 null Postpartum depression DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.642 EFR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93849 NICN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5287 BRD-K18562847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7395 CRCGN015_HEPG2_48H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.10942 Hyperglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.814 marker GeneRIF Biological Term Annotations 1.0 null Jugular vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.896 shared GeneRIF Biological Term Annotations 1.0 null rna polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.412992 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 CDR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14686 primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.865528 ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071388 status GeneRIF Biological Term Annotations 1.0 null dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22385 frequent GeneRIF Biological Term Annotations 1.0 null Autoimmune disease of gastrointestinal tract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.129 MIB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.516 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8254 COL1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97412 megakaryocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.183226 myenteric plexus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.7146 posteroventral (inferior) parietal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4107 Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06558 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.231527 Periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17515 than GeneRIF Biological Term Annotations 1.0 null SARS-CoV MA15_Day1-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.08854 Distal axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.808 VANGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.85765 mRNA_T_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-O5YT-0326-SM-32PKA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849671 Corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.906 implicated GeneRIF Biological Term Annotations 1.0 null suggested GeneRIF Biological Term Annotations 1.0 null TFG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44266 duodenum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.614167 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood platelet TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.682695 Obesity DisGeNET Gene-Disease Associations 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.29626 hsa-miR-320b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 positive regulation of cellular process GO Biological Process Annotations 2015 1.0 null Mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.394 KDM4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8164 conclusion GeneRIF Biological Term Annotations 1.0 null GSE135352_6_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null H2.35 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.523 BRD-K81706364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2725 autism GeneRIF Biological Term Annotations 1.0 null proclivity GeneRIF Biological Term Annotations 1.0 null oltipraz LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.01843 middle GeneRIF Biological Term Annotations 1.0 null Tetanus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 ATCAY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25933 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74731 CRCGN009_HEPG2_24H:O03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.06076 HDLM2 CCLE Cell Line Gene Mutation Profiles 1.0 null Mastocytosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 BRD-K93127164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46481 BRD-K39695412 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31137 GTEX-TKQ2-1026-SM-33HB7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.985399 GATA1_G1E-ER4_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJMC-2026-SM-3GADR GTEx Tissue Sample Gene Expression Profiles 1.0 1.11246 liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.5228 PDLIM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11498 MIN-6 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1954 primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55811 Villous cytotrophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.597 Dihydrobiopterin HMDB Metabolites of Enzymes 1.0 null heart valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.201635 GTEX-P78B-0826-SM-3NMCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.3602 GPR143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07136 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.60066 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838636 phenol-containing compound biosynthetic process GO Biological Process Annotations 2025 1.0 null TEX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19889 GTEX-X88G-0426-SM-47JZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.880364 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.847023 Cation channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.316 MAP2K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18392 CRCGN015_HEPG2_48H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.10761 CRAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23729 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-O5YT-0426-SM-3MJHD GTEx Tissue Sample Gene Expression Profiles 1.0 1.34631 Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73689 Toll-like receptor 1-Toll-like receptor 2 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.92 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.56902 implicate GeneRIF Biological Term Annotations 1.0 null KCNK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87224 PMC5836539-MSB-14-e7858-s005.xlsx-MITF_target_genes-MITF_transcriptional_target_genes_1_MITF Rummagene Transcription Factor Associations 2026 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.95752 symptoms GeneRIF Biological Term Annotations 1.0 null Fetal_Intestine_Large Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.26115 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.13379 Mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.03001 DDX51 Pathway Commons Protein-Protein Interactions 1.0 null Abortion, Habitual HuGE Navigator Gene-Phenotype Associations 1.0 null FH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09584 m2 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42698 neurological GAD High Level Gene-Disease Associations 1.0 0.305726 Biliary tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 COL7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50099 NCIH2196 CCLE Cell Line Gene Expression Profiles 1.0 2.09718 GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null hypothalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.53574 Cortical microtubule cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.945 pallor MPO Gene-Phenotype Associations 1.0 null PDS5B Pathway Commons Protein-Protein Interactions 1.0 null 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.44769 NCIH292 CCLE Cell Line Gene CNV Profiles 1.0 1.52764 type iii intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.256925 CLEC11A Pathway Commons Protein-Protein Interactions 1.0 null L-Tryptophan DrugBank Drug Targets 1.0 null cingulate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.307528 C11orf98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43586 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.301758 Personality Inventory HuGE Navigator Gene-Phenotype Associations 1.0 null PMC4404183__F2 PFOCR Pathway Figure Associations 2023 1.0 null LRRC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32681 cdx2_21074721_jejunum_epithelium_lof_mouse_gpl10773_gse23436 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.472139 POLR1H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22536 AKR1A1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00563988 CLU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99969 ARHGEF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28593 Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05679 aromatic compound biosynthetic process GO Biological Process Annotations 2015 1.0 null GNG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02229 Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bmmc cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23459 Hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 PTBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19911 lip TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.272997 GSE181959_3_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE60217_1_v_8_inosine_human RummaGEO Drug Perturbation Signatures -1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71857 WDFY3 Pathway Commons Protein-Protein Interactions 1.0 null abnormal heart left ventricle pressure MGI Mouse Phenotype Associations 2023 1.0 null Tongue epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.009 layer 1 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00129 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.19348 ICAM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83792 BRD-K50710005 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92795 Cerebral gray matter TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.635 cigarette GeneRIF Biological Term Annotations 1.0 null substance withdrawal syndrome; tobacco use disorder GAD Gene-Disease Associations 1.0 null Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.705 retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42285 cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null FRK MSigDB Cancer Gene Co-expression Modules 1.0 null predisposition GeneRIF Biological Term Annotations 1.0 null BRD-A69383366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49149 Osteoclast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.584 metal ion binding GO Molecular Function Annotations 2015 1.0 null BRD-K21996189 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.40758 BRD-K87901124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19936 BRD-K51370144 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19141 Hippocampal formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17089 amino acid metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.635528 SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.77578 TBL2 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K39600742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67103 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null polyclonal Phosphosite Textmining Biological Term Annotations 1.0 null EP400 Pathway Commons Protein-Protein Interactions 1.0 null KMS27 CCLE Cell Line Gene Expression Profiles 1.0 1.53011 Insulinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.179 MAC2A DepMap CRISPR Gene Dependency 1.0 2.85774 adrenal cortical hypofunction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.652484 GTEX-QDVJ-0626-SM-48U1T GTEx Tissue Sample Gene Expression Profiles 1.0 1.63495 missense GeneRIF Biological Term Annotations 1.0 null CCFSTTG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.60025 VCX3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77204 single GeneRIF Biological Term Annotations 1.0 null coated vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.408309 liver GTEx Tissue Gene Expression Profiles -1.0 -1.18547 Frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.154 GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89101 PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK Rummagene Transcription Factor Associations 2026 1.0 null Acute Disease HuGE Navigator Gene-Phenotype Associations 1.0 null primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.997198 Presubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90995 FZR1 Pathway Commons Protein-Protein Interactions 1.0 null TRIFLUPERIDOL-2HCL LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80973 haplotypes GeneRIF Biological Term Annotations 1.0 null appear GeneRIF Biological Term Annotations 1.0 null oxidation-reduction process GO Biological Process Annotations 2015 1.0 null ETV2-25802403-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831528 Encephalomyelitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 layer 5 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19663 GTEX-S4Z8-2026-SM-3K2A9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913187 genetically GeneRIF Biological Term Annotations 1.0 null GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33605 GTEX-VJYA-0926-SM-4KL1N GTEx Tissue Sample Gene Expression Profiles 1.0 0.976408 Glucose intolerance DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.786 amine biosynthetic process GO Biological Process Annotations 2015 1.0 null Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.597 Rheumatoid arthritis disease specific synovial tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.105 BRD-K50443235 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.83013 SPRTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.13683 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931203 personality disorders GAD Gene-Disease Associations 1.0 null CRCGN008_HEPG2_24H:G19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.43795 BRD-K49530286 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.06718 Traumatic brain injury DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.077 trichostatin A-2904 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Prediabetes syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.455 eosinophilia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.13742 PSMC1 Pathway Commons Protein-Protein Interactions 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Fetal_Intestine_Small Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.89609 Brush border COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.215 core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04053 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08903 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.532898 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944065 Jejunal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.84127 infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232881 men GeneRIF Biological Term Annotations 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94528 STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19951 IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.01973 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26333 GTEX-RVPV-0226-SM-2TF6W GTEx Tissue Sample Gene Expression Profiles 1.0 1.21521