association	dataset	threshold value	standardized value
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_31_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PI(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88008
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22713
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01233
PMC3348545-NIHMS263168-supplement-3.pdf-284-VENTX_VENTX	Rummagene Transcription Factor Associations 2026	1.0	null
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2997
PIP2(18:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.41381
disease	GWASdb SNP-Disease Associations	1.0	0.048793
HCC202	DepMap CRISPR Gene Dependency	1.0	2.27713
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052131
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60412
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77721
LN340	DepMap CRISPR Gene Dependency	1.0	4.38077
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77057
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918648
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
PIP3(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.0363
phospholipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65725
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051325
mouse	GeneRIF Biological Term Annotations	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02882
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971759
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82367
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56363
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91806
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994695
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38959
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84126
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
pi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
PI(18:3(6Z,9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51723
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22424
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25287
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7233
DMD_Deficiency_GDS2996_613_mouse_Cardiac muscles from 8-week (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832361
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12532
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5162-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84861
PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thrombocytopenia	MGI Mouse Phenotype Associations 2023	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42313
PI(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
SLC16A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51562
SNU719	DepMap CRISPR Gene Dependency	1.0	4.45768
CMLT1	DepMap CRISPR Gene Dependency	1.0	3.50419
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19226
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07884
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
proliferation	GeneRIF Biological Term Annotations	1.0	null
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7562
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987607
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17126
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24732
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4488
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81098
PIP3(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
pten	GeneRIF Biological Term Annotations	1.0	null
act	GeneRIF Biological Term Annotations	1.0	null
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0753
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36032
been	GeneRIF Biological Term Annotations	1.0	null
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.94896
PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-ZNF33A_ZNF33A	Rummagene Transcription Factor Associations 2026	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ICC9	DepMap CRISPR Gene Dependency	1.0	3.29018
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051282
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
MERO14	DepMap CRISPR Gene Dependency	1.0	2.84686
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34676
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.87733
PIP2(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051391
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81006
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Trachea-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.195869
PIP3(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
dominant	GeneRIF Biological Term Annotations	1.0	null
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18742
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82019
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839481
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871969
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
other	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877048
PIP(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
PI(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64461
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5434
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27527
PIP2(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5126
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49679
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971793
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3777
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6019
PIP(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0262
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.57516
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	2.11435
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_6_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59729
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3625
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03227
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42451
Trichocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
PIP2(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62199
neoplasm of head and neck	GWASdb SNP-Phenotype Associations	1.0	0.228002
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18751
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840477
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
NCIH838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52157
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PI(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
abnormal spine curvature	MGI Mouse Phenotype Associations 2023	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.517
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PI(22:2(13Z,16Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93824
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04332
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48013
cell type cancer	GWASdb SNP-Disease Associations	1.0	0.240321
PIP2(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837896
PIP2(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22424
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
HT-144	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36574
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cancer	GWASdb SNP-Disease Associations	1.0	0.036741
PI(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(15Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PIP2(16:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:2(11Z,14Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48575
PIP(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Ion transport domain	InterPro Predicted Protein Domain Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-99-8028-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERG	ChEA Transcription Factor Targets	1.0	null
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22145
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41957
Glyoxysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
PIP3(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5802
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
PI(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKHEP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28417
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41798
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36752
PIP(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL11	DepMap CRISPR Gene Dependency	1.0	7.56121
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAL29	DepMap CRISPR Gene Dependency	1.0	2.1083
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895786
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867448
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
PI(18:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905964
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9214
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47108
PIP(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
mouth disease	GWASdb SNP-Disease Associations	1.0	0.541061
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68415
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0325
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66498
Dual specificity phosphatase, catalytic domain	InterPro Predicted Protein Domain Annotations	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.107998
PI(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(22:5(7Z,10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06949
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7643
PTEN hamartoma tumor syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1714
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
PI(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04927
PIP(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43814
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
SLC25A44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00506
Metabolism of lipids and lipoproteins	Reactome Pathways 2014	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.290872
TE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.11435
PIP2(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02164
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48819
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4488
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3575
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17224
arrest	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0004
COLO205	DepMap CRISPR Gene Dependency	1.0	5.04206
HCFC1-20581084-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PIP(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26965
LUC7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39472
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EOMES	ChEA Transcription Factor Targets	1.0	null
catalytic	GeneRIF Biological Term Annotations	1.0	null
LARP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94568
PIP2(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(22:5(7Z,10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3766-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
WDR44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66119
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.571516
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2464
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56341
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75243
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02816
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PIP2(18:3(9Z,12Z,15Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GSE111247_2_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34164
CME1	DepMap CRISPR Gene Dependency	1.0	2.06527
SOX2	ChEA Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32527
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44095
PIP2(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69635
PI(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43878
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Sarcoma_SARC_TCGA-3B-A9HI-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3K6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50245
GSE168097_3_v_2_epinephrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Tensin phosphatase, C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12613
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48718
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069318
glycerophospholipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76537
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(16:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56106
transporter activity	GO Molecular Function Annotations 2015	1.0	null
PIP2(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(9Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.863341
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36892
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.407009
TIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0021
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926179
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
hsa-miR-7	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2110	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36914
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
recently	GeneRIF Biological Term Annotations	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7929
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.10722
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3541
Gall bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glycerophospholipid biosynthetic process	GO Biological Process Annotations 2023	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PI(20:4(5Z,8Z,11Z,14Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39328
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16927
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Brain Lower Grade Glioma_LGG_TCGA-KT-A74X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56147
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.249445
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.29486
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955782
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.48467
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
SK-HEP-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.0433
PI(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22536
KLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053772
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93209
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02443
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.135608
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31413
thrombocytopenia	IMPC Knockout Mouse Phenotypes	1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.174
COV504	CCLE Cell Line Gene CNV Profiles	1.0	1.77443
civsp	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.92617
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984976
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5153
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19603
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971026
Metabolism	Reactome Pathways 2024	1.0	null
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06116
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96515
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_36_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834171
PIP(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_21_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59182
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052766
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53318
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10686
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13635
OVCAR-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048543
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PLB-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12372
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10995
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27162
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12605
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907618
PMC10352658-Table_4.pdf-5-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881683
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950121
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04891
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54565
BRCA1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57635
PIP2(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62094
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73456
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT115	DepMap CRISPR Gene Dependency	1.0	2.05642
SH3BP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98752
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
RHBDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24849
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40668
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87544
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6263
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19634
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.4418
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIP2(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14113
PI(16:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Protein-tyrosine phosphatase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.331169
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948034
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0266
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36538
PIP2(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42216
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09905
PIP(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.37972
PI(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
behaves	GeneRIF Biological Term Annotations	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.53939
PIP2(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33678
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PI(20:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954883
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21742
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885466
H4	DepMap CRISPR Gene Dependency	1.0	3.96637
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-NEP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050332
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47378
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	1.41987
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6021
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982787
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7999
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903639
PIP2(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synucleinopathy	GWASdb SNP-Disease Associations	1.0	1.55827
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3328
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_217_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54255
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14067
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PIP2(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
abnormal sperm midpiece morphology	MGI Mouse Phenotype Associations 2023	1.0	null
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38324
PIP3(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
UMUC5	DepMap CRISPR Gene Dependency	1.0	3.11505
PIP2(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11801
HH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01628
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06
PIP(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.73452
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49714
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
golgi apparatus	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	1.9158
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03895
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41353
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44502
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933229
SW1990	DepMap CRISPR Gene Dependency	1.0	2.84859
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040204
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45973
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76476
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Phospholipid metabolism	Reactome Pathways 2014	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05167
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37242
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98441
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
PI(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56498
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.17816
PI(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59162
GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PIP(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6604
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896267
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2669
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48463
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25621
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.59917
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26941
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.027
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48959
PI(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37636
OVCAR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphatidylinositol biosynthetic process	GO Biological Process Annotations 2023	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16564
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259254
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84097
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09186
PI Metabolism	Reactome Pathways 2014	1.0	null
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PIP2(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
PI(16:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51737
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46005
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20837
Stage Iib Gallbladder Cancer Ajcc V8	DisGeNET Gene-Disease Associations	1.0	null
PIP(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95905
PIP2(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.0269
PIP(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIP3(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
phosphatidylinositol biosynthetic process	GO Biological Process Annotations 2015	1.0	null
kyphosis	MGI Mouse Phenotype Associations 2023	1.0	null
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58382
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32464
PI(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891467
NBSUSSR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.47893
artery disease	GWASdb SNP-Disease Associations	1.0	0.309232
PI(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Phosphatidylinositol-3,4,5-trisphosphate	HMDB Metabolites of Enzymes	1.0	null
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52963
PI(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1746
originally	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837754
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21187
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22736
SK-MG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25179
Lung adenocarcinoma_LUAD_TCGA-MP-A4T4-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
dephosphorylation	GO Biological Process Annotations 2023	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2883
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38171
PI(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84805
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936592
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23974
PIP(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03941
SW948	CCLE Cell Line Gene CNV Profiles	1.0	2.00997
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855059
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.665
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08863
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960572
PIP2(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06606
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30872
PIP(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
like	GeneRIF Biological Term Annotations	1.0	null
PI(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63024
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95869
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31891
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.20459
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64333
PI(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39157
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.11376
K562	DepMap CRISPR Gene Dependency	1.0	2.3978
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75851
PIP(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41079
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93081
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11062
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7159-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958739
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084058
SKGI	DepMap CRISPR Gene Dependency	1.0	4.48344
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41478
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79745
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96233
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
CAPAN-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphatidylinositol metabolic process	GO Biological Process Annotations 2025	1.0	null
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8847
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22138
described	GeneRIF Biological Term Annotations	1.0	null
PIP2(18:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96515
organelle part	GO Cellular Component Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22713
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33402
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055208
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12804
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02755
protein modification process	GO Biological Process Annotations 2015	1.0	null
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20202
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855739
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7749
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
PIP(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052272
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36159
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05295
PIP(16:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57408
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.976965
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24528
PI(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42721
PI(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88447
suppressor	GeneRIF Biological Term Annotations	1.0	null
PIP(16:0/20:1(11Z)) 	HMDB Metabolites of Enzymes	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.59632
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89762
MWP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7738
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83307
PIP(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4034
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83345
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20754
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64328
non-Hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
PIP(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
tissues	GeneRIF Biological Term Annotations	1.0	null
PI(22:3(10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.433753
PIP2(18:1(11Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7891-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0698
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13327
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967303
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34867
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56341
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
chr13_19464444_A_G_b38	GTEx eQTL 2025	1.0	1.10608
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78761
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7142
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.839662
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
Charcot-Marie-Tooth disease type 4B3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939295
Phosphoric acid	HMDB Metabolites of Enzymes	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12923
Centronuclear myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6398
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871969
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIP(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936592
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942588
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.043985
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02373
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32465
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6706
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87893
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_158_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75468
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EK-01A-22R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05384
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dolichol-phosphate-mannose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.174819
PTEN phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.593
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12225
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.510011
c2domain	GeneRIF Biological Term Annotations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04517
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978942
Golgi membrane	GO Cellular Component Annotations 2023	1.0	null
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3449
PIP2(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.59557
PIP2(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6642-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
PIP(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.407009
PI(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15079
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
GOTO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48782
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.313
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.074239
PIP2(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5922
PI(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3308-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00584
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.0433
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59119
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27113
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00695
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18533
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33229
signalling	GeneRIF Biological Term Annotations	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2772
glycerophospholipid biosynthetic process	GO Biological Process Annotations 2025	1.0	null
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05956
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1076
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41079
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
increased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
PIP2(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_41_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76971
chimeric	GeneRIF Biological Term Annotations	1.0	null
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830403
PI(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18178
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11634
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41852
phosphatidylinositol metabolic process	GO Biological Process Annotations 2023	1.0	null
PIP(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
496100430_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44129
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99976
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2658
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07966
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10805
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838569
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0753
Gallbladder Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Mitotic spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24285
PI(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
chr13_19470290_C_T_b38	GTEx eQTL 2025	1.0	2.02546
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25905
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.768701
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2211
PI(18:3(9Z,12Z,15Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
BACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60262
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5956
PI(18:3(9Z,12Z,15Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891315
PIP2(16:0/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF622	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12188
glycerolipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PI(16:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75551
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59247
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10501
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP3(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PI(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9893
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
PI(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
peptidyl-tyrosine dephosphorylation	GO Biological Process Annotations 2015	1.0	null
PI(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.53911
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98452
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56265
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
shown	GeneRIF Biological Term Annotations	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40137
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12858
PMC10290283-biol-2022-0622-sm3.pdf-409-TIGD6_TIGD6	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20318
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.19236
Phospholipid metabolism	Reactome Pathways 2024	1.0	null
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12559
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98099
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886534
mouth neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.461356
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07163
Liver fibrosis (total hepatic collagen content)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34465
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
PIP(18:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
LDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03322
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57177
more	GeneRIF Biological Term Annotations	1.0	null
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03467
PI(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
splicevariant	GeneRIF Biological Term Annotations	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23941
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.5415
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052033
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62304
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55064
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21283
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91183
PI(18:3(9Z,12Z,15Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
membrane region	GO Cellular Component Annotations 2015	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00233
PIP2(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55548
PI(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5512
PMC3698521-supp_jem.20120812_JEM_20120812_sm.pdf-26-HOXB6_HOXB6	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51116
PI(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68224
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Metabolism	Reactome Pathways 2014	1.0	null
impaired fertilization	MGI Mouse Phenotype Associations 2023	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44164
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14113
phosphatidylinositol biosynthetic process	GO Biological Process Annotations 2025	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883829
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74538
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7155
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46344
PIP2(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87005
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22088
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44467
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22826
DBNDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89159
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day1-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13767
PIP3(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839369
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.780273
asthenozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
PIP2(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58199
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23428
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.04276
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.83205
PI(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chondroid lipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
PIP2(20:3(8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824384
RPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74159
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PIP2(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.824215
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869942
increased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
PI(18:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28142
GP5D	DepMap CRISPR Gene Dependency	1.0	2.02831
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46566
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02134
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77738
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1925
PI(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952037
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132374
lipid biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Golgi cisterna membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PI(22:3(10Z,13Z,16Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090427
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.46568
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65078
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02031
PI(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
BICR22	CCLE Cell Line Gene CNV Profiles	1.0	1.54859
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42657
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45637
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06632
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.16922
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7292
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.35732
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19544
PI(18:1(11Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
GAPDHS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46245
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507849
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824246
Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040063
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0182
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15583
HCFC1	ChEA Transcription Factor Targets	1.0	null
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
PI(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
abnormal sperm physiology	MGI Mouse Phenotype Associations 2023	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIP(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987547
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03308
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98187
PI(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998017
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16929
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879609
dephosphorylation	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19586
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PI(16:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.208
PI(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
glycerophospholipid metabolic process	GO Biological Process Annotations 2015	1.0	null
PI(20:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27669
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66413
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74833
PI(18:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(18:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18472
inhibits	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78519
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.28432
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03498
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.71997
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75507
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853481
PI(16:0/22:4(10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
oaw42	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
496100661_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05877
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24654
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937612
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.49287
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39241
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55319
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0733
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3133	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PIP(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0753
hsa-miR-1197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PIP2(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17982
PIP(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37758
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216325
PIP2(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8387-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dinoflagellate hypocone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.33
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.34446
PMC2742312-1479-7364-3-3-221-S3.PDF-270-ZNF140_ZNF140	Rummagene Transcription Factor Associations 2026	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.69149
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81153
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.18156
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.06944
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41852
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57556
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82205
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4224
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.897848
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33019
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194082
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1104
PI(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08733
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KASUMI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71421
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3866
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54884
PIP(16:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
construct	GeneRIF Biological Term Annotations	1.0	null
liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.241196
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
PI(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2847
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63_01_329	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.96592
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC1005	DepMap CRISPR Gene Dependency	1.0	4.73581
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2211
effector	GeneRIF Biological Term Annotations	1.0	null
SYNCRIP_OE_GDS3186_84_mouse_wild type 129 mouse retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3869
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41246
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40991
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93515
PI(20:4(8Z,11Z,14Z,17Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3063
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02229
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99575
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15672
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23031
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2082
PIP(16:0/22:5(4Z,7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844829
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12686
Golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27776
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
Recycling endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
CNNM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88842
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37435
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3029
PIP(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TU-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(18:0/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(18:1(9Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62751
Charcot-Marie-Tooth disease type 4B1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8404
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27355
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44369
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.829104
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
NANOG	ChEA Transcription Factor Targets	1.0	null
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69619
cellular process	GO Biological Process Annotations 2015	1.0	null
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57483
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4396
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.61569
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21383
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3968
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
intracellular part	GO Cellular Component Annotations 2015	1.0	null
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41306
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848857
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30635
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99476
CDYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38166
PI(20:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_46_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PIP(20:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.119042
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828643
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.042735
EW-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973609
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DICER1_KO_GDS4504_586_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
PIP(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09403
PIP3(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30576
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.04962
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.510011
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02328
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928354
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.681
PIP(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494528
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4633-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01043
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30175
NB12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	7.21236
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09264
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
PI(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50761
abnormal spine curvature	IMPC Knockout Mouse Phenotypes	1.0	null
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73815
PIP2(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.497
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9077
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30862
PIP2(18:1(11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02457
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35419
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.8601
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
PI(22:5(4Z,7Z,10Z,13Z,16Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
Tensin phosphatase, lipid phosphatase domain	InterPro Predicted Protein Domain Annotations	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07254
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861219
COR-L23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15097
PI(18:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIP2(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calpain complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.036277
RUNX2	ChEA Transcription Factor Targets	1.0	null
PIP(18:0/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Stage Iia Gallbladder Cancer Ajcc V8	DisGeNET Gene-Disease Associations	1.0	null
PI(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PMC10260721-43657_2023_100_MOESM10_ESM.xlsx-MR_for_neuro-traits_FDR_0_05-Gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60429
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992354
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870223
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04355
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02378
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16656
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74035
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73323
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.47161
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
PIP(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11258
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.067905
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66033
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32276
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TUFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27271
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55278
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1289
PIP2(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95577
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3385
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52389
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57635
CISH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75015
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77703
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89262
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886477
ASPC1	DepMap CRISPR Gene Dependency	1.0	4.14755
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20911
PIP3(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4382-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(20:3(8Z,11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05384
TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kyphosis	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19194
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28511
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11872
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4965
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38949
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74454
PIP(20:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948579
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.843
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71309
bind	GeneRIF Biological Term Annotations	1.0	null
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162109
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931361
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25537
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.399
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01701
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73376
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134409
Scintillon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.367
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76639
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41678
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	1.8055
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04994
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
immunodeficiency-centromeric instability-facial anomalies syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25636
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930077
PIP(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94227
PI(22:4(10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
BECKER	DepMap CRISPR Gene Dependency	1.0	3.45203
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.17894
PIP2(18:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4971
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67744
PIP(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hydrolase activity, acting on ester bonds	GO Molecular Function Annotations 2015	1.0	null
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96448
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62247
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PIP(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_11_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69366
NUDT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73439
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830997
PIP2(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
NCI-H1355	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.0433
TP63_01_326	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.96592
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.311334
Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33508
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044518
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06122
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PI(20:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43821
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42988
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.02861
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44095
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877187
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PIP2(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
PIP(18:1(9Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856404
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
PIP(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00997
PIP(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP3(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:1(9Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.200831
PIP2(18:1(11Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.86
HCC1187	DepMap CRISPR Gene Dependency	1.0	4.17538
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12114
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.571516
OCIM2	DepMap CRISPR Gene Dependency	1.0	3.13498
phosphoprotein phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
PIP(18:3(6Z,9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70181
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69237
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1943
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38048
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27233
all	GWASdb SNP-Phenotype Associations	1.0	0.046903
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
PI(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19728
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5162
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14998
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46643
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985469
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2232
phosphatidylinositol-3,4-bisphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.625
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57491
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53345
PIP2(18:1(9Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_56_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL4	DepMap CRISPR Gene Dependency	1.0	3.19181
PIP2(18:3(9Z,12Z,15Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-127-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6557
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.61119
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73732
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35996
PIP(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
LYN	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904084
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.33145
Bannayan-Riley-Ruvalcaba syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
PIP2(18:3(9Z,12Z,15Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1734
PI(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36299
PIP[3'](16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445268
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.10215
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PI(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89246
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053006
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38419
PI(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
cellular_component	GO Cellular Component Annotations 2015	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.73
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphatidylinositol trisphosphate phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
PIP(16:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GIPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77349
golgi membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
rvh421	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
organophosphate biosynthetic process	GO Biological Process Annotations 2015	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069338
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
PI(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040316
PI(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978579
PIP(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.930566
PI(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9059
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.7138
PIP2(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64472
Synthesis of PIPs at the Golgi membrane	Reactome Pathways 2024	1.0	null
MAP3K7_knockout_246_GSE34417	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-4.03916
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(20:2(11Z,14Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61759
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07628
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28451
PIP(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
PIP2(16:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19637
PIP(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33718
RUNX1	ChEA Transcription Factor Targets	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891467
PIP2(18:2(9Z,12Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.33568
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23941
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolism of lipids	Reactome Pathways 2024	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93081
Stage Iii Gallbladder Cancer Ajcc V8	DisGeNET Gene-Disease Associations	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81969
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29416
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39154
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.6425
CAPAN1	DepMap CRISPR Gene Dependency	1.0	6.59136
LS	DepMap CRISPR Gene Dependency	1.0	4.51636
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39381
NCI-H1573	COSMIC Cell Line Gene CNV Profiles	1.0	2.11435
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922866
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8474
PIP(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
PIP(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052431
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25159
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(18:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978661
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1_knockout_210_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.42792
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphate-containing compound metabolic process	GO Biological Process Annotations 2023	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040924
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861525
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2408
PIP2(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77053
FEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47126
protein dephosphorylation	GO Biological Process Annotations 2015	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992992
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12776
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0772
PIP2(16:0/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920271
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72141
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860394
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.910432
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7658
PI(20:3(5Z,8Z,11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:2(9Z,12Z)/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11059
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41705
PI(20:4(5Z,8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4151
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(20:2(11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(9Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
TE-5	COSMIC Cell Line Gene CNV Profiles	1.0	2.11435
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.066258
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.52407
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0071
EWSR1	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Proteus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64821
PI(22:4(7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parkinson's disease	GWASdb SNP-Disease Associations	1.0	1.55827
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29996
SLC25A38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80449
vascular disease	GWASdb SNP-Disease Associations	1.0	0.236423
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8381
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21769
TTC642	DepMap CRISPR Gene Dependency	1.0	2.54866
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466885
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_51_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
COL26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51903
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08733
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088071
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.450194
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183126
PIP2(22:3(10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC4090166-pone.0102079.s006.docx-0-SAFB2_SAFB2	Rummagene Transcription Factor Associations 2026	1.0	null
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44308
phosphoinositide	GeneRIF Biological Term Annotations	1.0	null
PIP3(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20843
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58361
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31272
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846067
PI(18:0/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02031
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78478
phosphatidylinositol metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
ARV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28163
PIP2(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26711
PIP(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8239
PIP(18:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PI(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.72687
SUDHL8	DepMap CRISPR Gene Dependency	1.0	4.96606
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052272
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
PIP2(18:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45735
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03309
SNU1196	CCLE Cell Line Gene CNV Profiles	1.0	1.38031
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45625
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58551
COL9A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47235
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196886
PI(18:1(11Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70291
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Centronuclear myopathy X-linked	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
phosphatidylinositol trisphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
PI(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
Phosphatidylinositol phosphate phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.578
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88431
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
PIP2(16:0/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2399
negative	GeneRIF Biological Term Annotations	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57449
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
protein tyrosine/serine/threonine phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.119876
hsa-miR-148b-3p	MiRTarBase microRNA Targets	1.0	null
PIP2(20:3(5Z,8Z,11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
SF3B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13223
membrane	GO Cellular Component Annotations 2015	1.0	null
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.338
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42388
PIP2(18:1(11Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.62841
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS766T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	0.834874
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.124423
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
single-organism biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PIP2(18:1(11Z)/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18384
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48078
PIP(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989674
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.2213
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29357
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26884
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.789759
Liver Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
EDA2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48615
PIP2(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5342
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4947
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40509
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(20:3(8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(22:5(4Z,7Z,10Z,13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91451
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91732
PIP2(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78277
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glycerolipid metabolic process	GO Biological Process Annotations 2015	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28269
PI(18:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.928938
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99352
PIP(16:2(9Z,12Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
squamous cell carcinoma	GWASdb SNP-Disease Associations	1.0	0.541061
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34145
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PIP3(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26402
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
OV-7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55038
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10594727-13062_2023_428_MOESM14_ESM.xlsx-Sheet1-PPARD_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP2(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.31168
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97377
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00353
PIP2(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07952
PIP2(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.88837
PIP2(16:2(9Z,12Z)/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6003
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24996
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9766
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22462
PIP(22:2(13Z,16Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48919
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15219
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.35412
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04756
such	GeneRIF Biological Term Annotations	1.0	null
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62777
PI(18:3(6Z,9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PI(18:1(11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Gall bladder cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09037
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827869
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37662
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911125
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.37428
Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.10877
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37494
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9686
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31549
later	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931996
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29979
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.07316
phospholipid metabolic process	GO Biological Process Annotations 2015	1.0	null
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002594
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	1.41987
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89872
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50238
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71089
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29845
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842195
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
RET_mutant_23_GDS3319	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.70476
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43784
Macropinocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
RFXANK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37208
PIP2(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30394
PIP2(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
PI(20:3(8Z,11Z,14Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3854
PIP2(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26211
PI(18:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42519
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
golgi membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970946
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25431
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905964
Proteinuria	CTD Gene-Disease Associations	1.0	1.11707
ZSCAN22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79973
PIP2(18:0/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58757
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052765
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28424
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844637
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971203
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PI(16:0/22:3(10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09598
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
phosphatases	GeneRIF Biological Term Annotations	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.787531
IMR32	DepMap CRISPR Gene Dependency	1.0	3.47326
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.698181
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19131
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
PI(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14933
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.941411
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77005
Alkyl hydroperoxide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
PARP2_KD_GSE43981_676_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.25798
PI(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17961
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.25
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_387_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.924536
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.36111
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
strongly	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12166
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63205
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13293
PIP(18:1(11Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981398
PIP2(18:2(9Z,12Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08228
HCC2998	DepMap CRISPR Gene Dependency	1.0	4.44901
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09783
PIP2(20:4(5Z,8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PI(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72077
PIP2(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.36
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
PI(18:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59291
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Triglycerides Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1004
High Density Lipoprotein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.33801
DIDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77842
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40762
Early endosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68968
PI(18:2(9Z,12Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08303
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02031
protein tyrosine phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.84476
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998017
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056585
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75712
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044131
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825418
PIP2(20:3(5Z,8Z,11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177029
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96626
PIP2(16:0/22:2(13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61139
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40981
PIP2(18:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37473
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89815
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.42328
PIP(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PIP(22:4(10Z,13Z,16Z,19Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4757
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61459
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10579
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26079
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	3.03655
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10501
ZNF28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44337
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15127
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.44107
PIP2(18:1(9Z)/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(22:3(10Z,13Z,16Z)/16:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928354
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78931
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950608
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5212
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08933
PIP2(18:2(9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8041
MAGI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59778
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995151
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6109
phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
PI(20:3(5Z,8Z,11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23078
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60589
EPHA4_knockout_227_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.53734
PIP3(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16461
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03156
PI Metabolism	Reactome Pathways 2024	1.0	null
PIP(20:4(8Z,11Z,14Z,17Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Liver Cirrhosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
PIP(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03472
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052224
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5218
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320826
PI(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11755
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57787
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01637
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30281
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891467
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309335
MCF-10A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
PIP2(18:1(11Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12759
PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PIP(20:2(11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
OV-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PI(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
PIP(20:4(5Z,8Z,11Z,14Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
carcinoma, hepatocellular; liver carcinoma; liver cirrhosis; liver neoplasms	GAD Gene-Disease Associations	1.0	null
PI(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968733
PI(18:2(9Z,12Z)/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8259
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP2(16:2(9Z,12Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039794
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928495
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49021
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16335
PIP(18:1(9Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
PIP(18:0/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0916
PIP(20:3(5Z,8Z,11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53805
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.45004
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4181
LGR4	Pathway Commons Protein-Protein Interactions	1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859813
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBFOX2_02_101	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.41504
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.17894
PIP(20:3(8Z,11Z,14Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79226
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.837896
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894736
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00434
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(18:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82061
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41079
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1083
PIP2(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112826
ChIP_HCIF1_20581084	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36203
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12717
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.50768
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8604
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11106
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.946
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59895
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91874
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62736
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050564
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10411
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2947
homologous	GeneRIF Biological Term Annotations	1.0	null
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04933
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
PI(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87791
PIP(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40876
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55144
PC3	DepMap CRISPR Gene Dependency	1.0	3.45396
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	1.81571
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23836
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9342
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphoric ester hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
PIP(18:1(11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(16:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
HCFC1-20581084-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8591
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13775
PIP(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976439
UACC893	DepMap CRISPR Gene Dependency	1.0	6.87552
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
c4i	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
Cowden syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
EOMES-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915453
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14666
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.5195
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_26_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
PIP2(18:1(11Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
QIMR-WIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(20:4(8Z,11Z,14Z,17Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931361
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.42335
Pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5269
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08954
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP(20:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95311
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911207
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38347
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23911
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17210682-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_7-Supplementary_Table_7_ETV6-repressed_genes_defined_by_dTAG_at_24_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846067
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.881988
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58519
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84243
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11972
PI(20:4(5Z,8Z,11Z,14Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67359
PI(16:1(9Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PI(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058194
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4721
SKMEL19	DepMap CRISPR Gene Dependency	1.0	5.1933
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP(16:0/20:2(11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52271
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9267
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32606
PI(22:4(7Z,10Z,13Z,16Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
PIP2(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
PI4KA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26115
PI(20:3(5Z,8Z,11Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.168
UQCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77618
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PI(18:1(9Z)/18:3(9Z,12Z,15Z))	HMDB Metabolites of Enzymes	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5019
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4761
phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
Congenital structural myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46053
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.154772
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36999
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.0433
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.264785
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900403
PIP3(16:0/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Phosphatidyl inositol phosphate pathway	WikiPathways Pathways 2024	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40122
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13037
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
PAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60924
SETSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20078
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39086
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877859
MKN74	DepMap CRISPR Gene Dependency	1.0	3.62798
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98816
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	1.41987
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35536
PI(20:4(5Z,8Z,11Z,14Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87005
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02562
Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65756
3-phosphoinositide degradation	HumanCyc Pathways	1.0	null
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89472
SMARCA4-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
PI(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.831833
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Water	HMDB Metabolites of Enzymes	1.0	null
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3817
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19889
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIP(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889118
increased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28026
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869308
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09839
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057613
Kna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
organophosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
PI(18:1(11Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9343
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37024
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphatidylinositol phosphate phosphatase activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12313
PIP(20:3(8Z,11Z,14Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCL22	DepMap CRISPR Gene Dependency	1.0	2.43723
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.7524
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Stage 0 Gallbladder Cancer Ajcc V8	DisGeNET Gene-Disease Associations	1.0	null
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08338
OVCAR8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69509
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.956
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIP2(20:1(11Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41079
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.17894
PI(20:0/20:4(5Z,8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
increased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09921
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846773
PI(18:0/20:4(8Z,11Z,14Z,17Z))	HMDB Metabolites of Enzymes	1.0	null
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51478
KKU213	DepMap CRISPR Gene Dependency	1.0	2.20849
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05251
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46405
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18982
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_16_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PIP2(20:1(11Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051648
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1819
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94638
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937325
Gall bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
Caspase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78252
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883108
TRPV4_DEPLETION_GDS4851_89_mouse_3T3-F442A adipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	2.88442
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
CCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56081
PIP2(20:3(5Z,8Z,11Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
CIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75025
PIP(18:1(9Z)/18:0)	HMDB Metabolites of Enzymes	1.0	null
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hela	GeneRIF Biological Term Annotations	1.0	null
PIP(18:2(9Z,12Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.849806
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.86772
Perturb_542_OE_EWSFLI_SRP168621	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.82869
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PI(22:3(10Z,13Z,16Z)/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5095
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6295
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914505
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.33639
LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
phosphatidylinositol trisphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04527
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0244
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1694	DepMap CRISPR Gene Dependency	1.0	2.30719
PIP(18:2(9Z,12Z)/20:1(11Z))	HMDB Metabolites of Enzymes	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56811
PIP3(18:1(9Z)/20:3(8Z,11Z,14Z))	HMDB Metabolites of Enzymes	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91652
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86201
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reported	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88664
PI(18:1(11Z)/20:3(5Z,8Z,11Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37331
HCC44	DepMap CRISPR Gene Dependency	1.0	3.03915
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15476
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9002
496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28189
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41001
PIP(18:1(9Z)/16:0)	HMDB Metabolites of Enzymes	1.0	null
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32563
channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75463
PI(18:3(6Z,9Z,12Z)/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98552
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14744
PMC5630028-supp_gr.220533.117_Supplemental_File_S9_TCGA_mutation_data.xlsx-SMGs_in_TP53_mutant_tumors-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51715
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03214
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96515
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04481
PIP2(16:0/22:4(7Z,10Z,13Z,16Z))	HMDB Metabolites of Enzymes	1.0	null
PI(16:1(9Z)/16:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PI(22:3(10Z,13Z,16Z)/18:3(6Z,9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73266
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79365
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65995
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
carcinoma	GWASdb SNP-Disease Associations	1.0	0.541061
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93081
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19067
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Alpha DNA polymerase:primase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73455
Lung squamous cell carcinoma_LUSC_TCGA-22-4607-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Phosphate	HMDB Metabolites of Enzymes	1.0	null
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2445
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836587
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36246
phosphatidylinositol-3,4-bisphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22674
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.81439
SOX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4362
KMBC2	DepMap CRISPR Gene Dependency	1.0	2.92094
PIP2(18:2(9Z,12Z)/20:0)	HMDB Metabolites of Enzymes	1.0	null
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85196
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLNS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08206
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21551
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85008
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88501
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67699
SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Synthesis of PIPs at the Golgi membrane	Reactome Pathways 2014	1.0	null
PI(16:0/22:5(7Z,10Z,13Z,16Z,19Z))	HMDB Metabolites of Enzymes	1.0	null
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84227
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96515
PIP2(20:0/18:2(9Z,12Z))	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039424
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
QGP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96544
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.384
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824235
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1116	COSMIC Cell Line Gene CNV Profiles	1.0	2.11435
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Stage Iv Gallbladder Cancer Ajcc V8	DisGeNET Gene-Disease Associations	1.0	null
TSNAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91841
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71229
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052041
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01621
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01256
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8473
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein-tyrosine phosphatase-like	InterPro Predicted Protein Domain Annotations	1.0	null
PIP2(16:0/18:1(9Z))	HMDB Metabolites of Enzymes	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1388
SW962	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3437
PIP2(20:4(8Z,11Z,14Z,17Z)/18:1(11Z))	HMDB Metabolites of Enzymes	1.0	null