association	dataset	threshold value	standardized value
Celiac Disease	DisGeNET Gene-Disease Associations	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
rotenone-5915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64451058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50754
SKNO1	DepMap CRISPR Gene Dependency	1.0	2.23177
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21189
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938556
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mitochondrial outer membrane	GO Cellular Component Annotations 2025	1.0	null
CTSB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K73376409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7402
BRD-K95153342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36709
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45215
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85189
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06681
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75932
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.677
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37354
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1365
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28171
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68796
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22653
PMC3807112-srep03041-s6.xls-ELK4-Gene_Symbol_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.05482
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1571
trichostatin A-2370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20279
BRD-K66973998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38117
aminophenazone-6818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25333
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875049
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19508
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3093
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50149
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8398-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.25669
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35039
BRD-K73604422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30423
zalcitabine-2932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39467
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2322
tiratricol-2096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ewing's sarcoma_Renal Tissue_GSE1822	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.1119
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51767
Perturb_2525_KD_SYF2_SRP185438	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.12724
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943376
A549_Trichostatin A_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0085656
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC3	ChEA Transcription Factor Targets	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0051
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.74923
PMC10898050-12967_2024_4947_MOESM2_ESM.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_between_the_TCF7_CD8_memory_T_cells_and_the_other_memory_CD8_T_cells_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
corticosterone-3244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92153
isradipine-3129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K27178321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35098
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25481
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31504
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213746_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7021759-41467_2020_14682_MOESM10_ESM.xlsx-upregulated_genes-Table_S7_Upregulated_genes_in_SKNMM_and_U2OS_cells_with_MYCN_induction_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51697562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03969
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03872
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18864235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92241
18504433-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
lymphoepithelioma-like carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
AC-11-BO01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212138
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65625
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676309
pioglitazone-7083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.393
BRD-K94409042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88631
BRD-K09972656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15706
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22698
BRD-K11428617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66811
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.488
mefexamide-7478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31039
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82216975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9443
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.2609
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r1 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05673
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2074
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60044
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53357
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45584
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09591
fluspirilene-6463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.911708
NCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5231
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74275
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79801
CRCGN015_HEPG2_48H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09684
Perturb_6481_KD_SERBP1_ERP118886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31986
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986857
guanfacine-5621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-1103-6019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36755
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
moxisylyte-1682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17852428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12018
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39585
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8382
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M-VAC protocol	CTD Gene-Chemical Interactions	1.0	null
Perturb_3772_KD_BEGAIN_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.5227
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18855
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61247793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24716
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1118
Lung squamous cell carcinoma_LUSC_TCGA-98-A538-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97682096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01724
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81128
BRD-K25974714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62079
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42805
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AU-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12240312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24139
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.45053
triprolidine-7408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154282
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43751
CRCGN010_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02076
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15254
BRD-K20984459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1714
Tendinopathy	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75135426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23172
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02439
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7b-5p	MiRTarBase microRNA Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3049
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00442
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20236
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05637
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-860-5679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51600962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00126
Skin melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82891
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2471
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45937
BRD-A01759464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80039
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04992
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.8452
BRD-K36815183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14854
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20399
Perturb_6905_OE_EVI1_SRP344381	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.5003
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.20307
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22534
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26341
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_DMAP1_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HIPK4	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846279
NB17	DepMap CRISPR Gene Dependency	1.0	7.30602
BRD-K85474153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12699
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.408
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392963
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3218
ceftazidime-5054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10677
GSE246911,GSE246913_4_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pyrazinamide-2839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826321
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.68018
D341Med	DepMap CRISPR Gene Dependency	1.0	6.21604
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8669-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1792_COQ3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.629914
abnormality of the tongue	GWASdb SNP-Phenotype Associations	1.0	0.463779
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19339
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9214
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.55614
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-28-GJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248955
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324483
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82789
BRD-K18930370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01589
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.063561
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.1187
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36467
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1943
Necrosis	CTD Gene-Disease Associations	1.0	1.32637
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86729
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99742
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16231
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844203
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0902
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.213727
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Insulinoma	DisGeNET Gene-Disease Associations	1.0	null
rolitetracycline-5331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mitochondrial fusion	GO Biological Process Annotations 2025	1.0	null
BRD-K92291448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18705
BRD-K78866450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78109
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.778164
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10256
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30668
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71786
retrorsine-2129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05668
flutamide-3885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06373
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491005
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43701
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16668
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78306305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70543
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1569	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.05528
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371119
Perturb_8822_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.1837
biotin-2428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1351
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01558
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K95460104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40147
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38242
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0566
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1572
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3545
NUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.3584
BECN1	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85955
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883995
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34701
piretanide-6828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K45472595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19248
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61015
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TMEM158	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566927
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22655
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
triflupromazine-1813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
terguride-6299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_11467_KD_SRSF1_SRP290964	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.30447
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.71059
GSE134986_2_v_8_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ICC10	DepMap CRISPR Gene Dependency	1.0	3.40923
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295423
molindone-2917	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00327
PEO4	DepMap CRISPR Gene Dependency	1.0	2.3892
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33731
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29129
BRD-K07350528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31915
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66884
Sumatriptan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
spironolactone-5781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11788427-41467_2025_56543_MOESM6_ESM.xlsx-Spearman_High_MYC-Unnamed_6_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21429
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.58516
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PIK3R4	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ID-90-NM43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303998
PTOV1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9630_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.33684
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1628
BRD-K01639528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29917
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23305
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.509693
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lidoflazine-6278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62152527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83497
DD-30-SX80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286001
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3128
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastric corpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00127
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
8651_TAF10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.569081
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06332
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.2121
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68939871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55347
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412529
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84095
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MKN1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
rolipram-6449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EF-01-LB20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326396
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7286
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58391
Sarcoma_SARC_TCGA-DX-AB2X-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29398
ZNF384	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74540252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39596
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.289
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836686
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41203
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34766
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.97113
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31875
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19811
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00533
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71449
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557769
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39417
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67655
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12853587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10945
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.5902
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4294
15814643-Table3	GeneSigDB Published Gene Signatures	1.0	null
clebopride-2646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5926
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18694
Brain Lower Grade Glioma_LGG_TCGA-HT-8013-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.999708
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07529
SC-19220-7060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03772
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6687
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62577212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22015
Sepsis_Hepatic Tissue_GSE1781	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.87966
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11778
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23225
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44865
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36076
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39324
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203043
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.1809
cinchonidine-7190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0784
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955124
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68486
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.593335
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40566
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.476092
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trapidil-7475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluocinonide-3839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65105
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05902089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66282
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
molindone-4784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_9_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.36076
trichostatin A-5260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977836
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847326
BRD-K55237592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16429
PMC5541666__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K37092508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06803
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06055
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.24414
KMS-11/TKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206545
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51851
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09064
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00993
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356532
ketanserin-4995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	1.67786
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995302
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13261
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01852
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
ampicillin-1530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10846
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27433
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15584
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962729
BRD-K90325960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59446
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11331
BRD-K41189799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02979
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.720788
BW-B70C-1132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04251837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13404
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876242
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9852
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6005
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05777
MET_knockout_263_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56205
MRTFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09537
BRD-K72467884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69279
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54100199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78418
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11952
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-74-RX30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219281
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCM7	Pathway Commons Protein-Protein Interactions	1.0	null
YTHDF2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01844
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897347
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82521339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88662
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K77221872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08379
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2335
zuclopenthixol-2936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A30369394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53745
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31217
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70502
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35281
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5607
benzthiazide-4952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
0316684-0000-7093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66461
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL23_LUNG	CCLE Cell Line Proteomics	1.0	5.74258
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664567
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
FADU	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.59187
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
salsolinol-2791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
u87	HPA Cell Line Gene Expression Profiles	-1.0	-0.946051
PMC7933708-mmc2.xlsx-DNMT-target_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dexibuprofen-5311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39108
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17593
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293979
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75303
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31854
loracarbef-3532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.837494
oxamniquine-4124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.729346
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAF1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1616
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fursultiamine-6630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02161
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11445_KD_GATA2_SRP178865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.46532
hek293	HPA Cell Line Gene Expression Profiles	1.0	2.10383
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38789
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41298
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KNS60	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6097
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.97814
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
crotamiton-5689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33459
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0307
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32745
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
miconazole-4960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.565493
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27982554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04915
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5195
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34064
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastric adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63962
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69624346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41048
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.570396
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19005
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1411
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
BRD-K13646706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26451
RFX5	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5394
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.91215
theophylline-4228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-501-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
FOXP3	ChEA Transcription Factor Targets	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32181
BRD-K19139070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31982
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.987856
TOM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19728
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26247
rosiglitazone_homo sapiens_gpl96_gds2705	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE123943_4_v_5_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 65	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85336956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68482
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47S-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21659
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1986
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIMS2	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891932
foliosidine-4295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15757
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8181
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09062
Dorsal endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14371
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39001
BRD-K14763154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4847
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hs-746T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.40554
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61522760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39193
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29197
GSE144484_0_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08996393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75228
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867191
mitochondrion-mitochondrion outer membrane tether activity	GO Molecular Function Annotations 2025	1.0	null
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metacycline-2901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969175
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928221
AREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10803
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18056
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.83139
BRD-K43316594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09435
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72152
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13386
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06014
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00007
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05033
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12104
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43846
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863251
hsa-miR-3617	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.3352
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283358
Organelle envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.501
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PF-00562151-00-6907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35276
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04114
dacarbazine-6816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66898
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21644
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37242
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APD668	DeepCoverMOA Drug Mechanisms of Action	1.0	0.49
BRD-K81281620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72198
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.538258
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.64648
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985637
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.10952
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00542622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22114
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09604
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K52868251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07638
Perturb_3834_KD_PRR14L_SRP162816	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.41869
BRD-K63864310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.31925
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6745
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24223
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06324
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10996544-media-4.xlsx-Spearman_High_MYC-Unnamed_7_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40054
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72748
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K32280984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64293
CRCGN013_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61103
harmalol-5495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29399
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.63801
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43888
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12713
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.6014
mantle zone of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1437
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40431
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus-7001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59901
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96257
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507703
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05073
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30919
urapidil-6455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
methoxsalen-5007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62062
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08611
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.70195
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.72613
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.708939
valinomycin-5957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921587
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25608
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.45418
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1575
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15798_KD_EMP2_SRP265560	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.0174
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64719
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71135
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10596
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13928
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03583
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06479
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
iopromide-3481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44613
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45531
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.17936
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65525
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K48777375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28519
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.5744
Perturb_16475_KO_Irf6_SRP173803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.75818
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08656
NCIH650_LUNG	CCLE Cell Line Proteomics	1.0	4.28555
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04204
GSE131649_2_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DHRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05901
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02282
BE-38-UW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318693
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37043
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36714
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4066
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07816
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866022
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22313
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26109
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74979
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74892102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03099
Perturb_266_KO_ADIRFAS786_SRP366780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.41406
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
BRD-A68123879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24423
17597811-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36516
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951978
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.89058
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28167
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825338
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09439
BRD-K72934808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38939
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47961
TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7756
picotamide-6787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824465
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8403
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244215
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
quercetin-917	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	3.74444
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72488
MTA3	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.052742
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.827718
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.35816
CRCGN017_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07134
Perturb_2980_KD_Mbnl1/Mbnl2_SRP057123	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.51663
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13169
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML1-CLOSEST_GENE_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
meclofenoxate-3707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.58207
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
methotrexate-2041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59948
TRAFD1	Pathway Commons Protein-Protein Interactions	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19672
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76508844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23681
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948037
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18942
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27012
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30197
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45423
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
JHH-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.20009
BRD-K04443775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01311
FOXO1_01_322	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.75044
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29784863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1076
FOXP2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02546
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22255
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69777784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09323
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62185
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40947
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.27452
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86039224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37477
perphenazine-5698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.52733
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.25361
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22716
Perturb_14529_KO_Gata4/Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84836
hsa-miR-3648	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Perturb_10821_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5149
mitochondrion organization	GO Biological Process Annotations 2025	1.0	null
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9055
pentamidine-639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02573
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53745
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5272
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22345
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41842
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39543844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09091
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09496
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r1 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05572
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHA-00767505E-6591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41407
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17912
BRD-K63383299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14323
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57289
KMRC20	DepMap CRISPR Gene Dependency	1.0	3.75867
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88187
Perturb_8821_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.4145
NFIC	ENCODE Transcription Factor Targets	1.0	null
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03575
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.92063
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83022
methylergometrine-6704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855416
MV411	DepMap CRISPR Gene Dependency	1.0	2.96232
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.62422
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16383
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.625
GTEX-V955-0326-SM-4JBGV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875265
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4263	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18122
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01588
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.924075
IRS4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K48266244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08117
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
piromidic acid-2996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899203
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12349
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02302
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955124
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210253
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84165
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4319_KD_Fos_SRP075838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.2436
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.97
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
dequalinium chloride-1276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04302
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40935
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79616
BRD-K12469242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20028
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
(+/-)-catechin-4837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268412
Perturb_15796_KD_EMP2_SRP265560	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.3915
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22234
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prasterone-6474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H-89-6921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
BRD-K46121327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62796
A4FUK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40207
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13726
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-5233	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05572
Perturb_10781_KO_Ahr_SRP326814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.29383
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52381
BRD-K38111331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0273
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05384
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K67183010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04832
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.03828
Perturb_14813_KO_Septin2_SRP398422	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-A26952628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13497
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64353470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72931
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
3214_FTSJ3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.671531
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831876
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28218
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843404
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10822
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968989
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862739
Perturb_1367_KD_IGF2BP1_SRP252209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31963
PMC3669416-pone.0064838.s001.xls-mHTT-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17122222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26324
BICR22	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23203
BRD-K86721033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16138
PMC3807112-srep03041-s6.xls-GABPA-Gene_Symbol_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11062_KO_Jup/Ctnnb1_SRP304535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.6629
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.83534
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38548
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52219
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32768
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01952
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03283
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59217
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10289
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18714
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S0-EE-XMXE_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260853
BRD-K70876639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33797
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924315
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1077-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54068
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253773
BRD-K28720546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89397
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20805
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84958
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.15592
BRD-K71005143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47859
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837975
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166317_2_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-52-FW03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216507
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.7083
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43942
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KELLY	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.7447
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13925
procaine-1838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8085_SLC43A1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.575263
EOMES	ChEA Transcription Factor Targets	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79971
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849106
BRD-K07502463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05533
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38409
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGI-6780	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
demeclocycline-4267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0051
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07986
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45284
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38922
trichostatin A-3510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7193
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.938552
GSE143662_0_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62942008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31722
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.831323
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2433
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.342658
papaverine-5769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.437551
BRD-K55835264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13675
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22417
BRD-K15008902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94299
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22059
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30327
Perturb_12958_KO_KDSR_SRP308393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.03469
Mean platelet volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.68313
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48808
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A431	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.95548
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SFXN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884236
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839677
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872161
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	DepMap CRISPR Gene Dependency	1.0	4.74924
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453545
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20214
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08861
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31624501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15553
BRD-A03668899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5574
dl-alpha tocopherol-1320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
denatonium benzoate-5061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
methoxsalen-6661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
968_C12ORF60_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.55556
BRD-K21423945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25877
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.825894
chenodeoxycholic acid-7433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62202988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62371
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8216
HC-18-NB46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201108
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-6.39389
GSE209601_2_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52228
CRCGN015_MCF10A.TP53.M_24H:L06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2059
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10052
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IE-80-DC24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.292314
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.90909
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00684
TE-11	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.79547
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02217
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50706
BRD-K52261313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91303
BRD-K79887735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00588
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.541
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.533715
7332_RNASEK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533663
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50951
BRD-K82362034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03949
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44692299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76695
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97806
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27943
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09828
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78371
trifluridine-5819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90657
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid-1639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_14674_Mut_GCK_SRP089943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.11545
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-OVERLAP_GENES_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
Epstein-Barr virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152458
PHA-00851261E-4333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.27998
BRD-K37271110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.551
5869_NUDT21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502744
IC-80-CT90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216769
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.42587
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
RS411	CCLE Cell Line Gene Expression Profiles	1.0	1.42526
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.984988
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
perhexiline-5501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1415
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2794
ROS50	DepMap CRISPR Gene Dependency	1.0	3.44621
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29561
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19708
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37121
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58431
furazolidone-4098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51865
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AKAP8L	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955124
Perturb_772_KD_SRRM2_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66775
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03369
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09954
9147_TNNT2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.586646
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04417
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43672
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91684
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
BRD-K17751525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15974
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24563
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57399
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nadide-7227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JL1	DepMap CRISPR Gene Dependency	1.0	5.78697
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-97-IV02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295053
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65729622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46878
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5451
dextromethorphan-2636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etofylline-5467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73290515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21954
indapamide-2322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856797
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56717
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84989
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06213
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79502
dropropizine-5531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31348453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21664
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-500a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K82126187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21209
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0608
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.31077
griseofulvin-7363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863964
16651414-Supp4	GeneSigDB Published Gene Signatures	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2129
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94096
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05657
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.03161
CBX2_KO_GDS4445_353_mouse_E11.5 XX embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6331
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76634
scopolamine N-oxide-1415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07025286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92875
Perturb_2121_KD_PRMT5_SRP276651	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.89483
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68463
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.512
verapamil-5387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985866
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310147
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16461
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48777
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15968
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380811
salsolidin-2824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liothyronine-4947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07356
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.159
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MB-49-LL22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256925
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20482
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
fulvestrant-6918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K24946605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02672
PARVB	Pathway Commons Protein-Protein Interactions	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984456
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.97
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1382
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04985
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.50848
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09168
benzydamine-5811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11241
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6631
praziquantel-7228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56766
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01641
Platelet Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K06250424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03861
BRD-K62982533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47115
PC-87-OG75_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238143
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.195
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909794
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67933
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
BRD-K47083242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7879
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34303
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHA15_KO_GDS4341_145_mouse_pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03012
BRD-K36575696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28082
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14472
XRN2	ChEA Transcription Factor Targets	1.0	null
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	1.81623
BRD-A22773530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35188
BF-00-PE90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210331
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22688
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903405
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373907
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445759
SF295	BioGPS Cell Line Gene Expression Profiles	1.0	0.828023
BRD-K19389825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40978
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.237444
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42426
SARS-CoV_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41007
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66331
MYLA	DepMap CRISPR Gene Dependency	1.0	3.72336
tetrandrine-5821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891264
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.997168
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11199
MYOG	ENCODE Transcription Factor Targets	1.0	null
NUP188	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPB15	CCLE Cell Line Gene Expression Profiles	1.0	1.99601
JHH-7	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9026
BRD-K58971526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25242
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36534
Cystic Fibrosis_Intestinal Epithelium_GSE765	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.908831
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
butyl hydroxybenzoate-6446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97562463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48095
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48897
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fulvestrant-7096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ethanol_rattus norvegicus_gpl341_gds2107	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940242
EPOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049032
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.847878
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33287655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48378
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43025
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54715
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65077
PMC8906867-pbio.3001569.s011.xlsx-HEK_and_SupT1_up_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01825
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23922
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69448
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54793
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06498
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400264
BRD-K34197007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68427
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.584
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GLUD1	Pathway Commons Protein-Protein Interactions	1.0	null
CLN6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K10849007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18149
TE-9	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.54961
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16819
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18101782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18533
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828988
aciclovir-2044	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09484
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16378
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.974538
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TD-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00681
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_HEK293DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
DCP1A	ChEA Transcription Factor Targets	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13962
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACSL3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13793
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20711
XRN2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
eticlopride-5695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58544
rectum_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.37358
amprolium-1979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39684
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42233
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.066
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
luteolin-3041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHUK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488229
adrenosterone-5045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
troleandomycin-1965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896598
BRD-K12665145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07137
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12411
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92142
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A76905089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37088
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07197
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24817
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26469
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.972747
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25176
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3237
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML2-CLOSEST_GENE_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
STOCK1N-28457-6906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10169
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.950144
KIAA0226	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71B-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.401
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LPCAT1	Pathway Commons Protein-Protein Interactions	1.0	null
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20142
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pirlindole-5497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02681754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58284
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33493
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42736
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38146
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14287
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960659
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.65722
NCI-H2810	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.45659
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60030763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17287
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14281
hydrochlorothiazide-1987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
BT549_BREAST	CCLE Cell Line Proteomics	1.0	3.00638
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977836
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39048
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330908
AD-86-ES28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348675
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04176
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63444
Perturb_10710_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.96539
HSC-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.08311
BRD-K98224452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82628
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20017
G-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.2268
DOV13	DepMap CRISPR Gene Dependency	1.0	2.6318
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09525
Perturb_321_OE_primiR450a_SRP189900	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.8726
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32232
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899961
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.98361
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.023787
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.832522
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KNS60	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55287
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02792
Banded collagen fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17803
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56942203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13171
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00158
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320894
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09063
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.855559
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07237
BRD-K40222892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11638
BRD-K31660953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08334
ST3GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0743
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25061
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.97
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84958
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09821
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982955
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908426
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16674
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308622
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18149
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.0111
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0533
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Autosomal recessive nonsyndromic deafness 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.864153
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26903
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.742461
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3653
sirolimus-5204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11404
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1294	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03484
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69902
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471759
BT483	CCLE Cell Line Gene CNV Profiles	1.0	1.72459
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36409
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34188
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.855749
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22696
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
sparteine-4391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HUPT4_PANCREAS	CCLE Cell Line Proteomics	1.0	2.9509
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68801
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7568_KD_CPSF6_SRP327319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.52052
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64833
GSE198165,GSE198166_0_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55877
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526385
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.833754
Mitochondrial envelope	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K26766324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68814
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45427
BRD-K79688948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03108
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5409
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Koelliker-Fuse subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38526
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64567083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92958
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14842
nisoxetine-3117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1707
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899203
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22234
BRD-K07164317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45551
superior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25239
BRD-K72609226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60985
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trifluridine-7176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SD-82-GT69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310239
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1541
acetohexamide-1870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882267
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312607
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898406
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372403
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976293
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29016
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.52981
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228225
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1_01_270	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.18939
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K23867157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06895
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39699
RERF-GC-1B	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.67119
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85707
BRD-K31851055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63013
suxibuzone-6065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBC1D7	Pathway Commons Protein-Protein Interactions	1.0	null
TE5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64965
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61924304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03936
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943337
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02448
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49114
etamsylate-4576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91206
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32185628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69473
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06086
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84044
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bezafibrate-4999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23086
parahippocampal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29605
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.17496
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trimetazidine-5479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4521	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8479
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10424
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IL22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573026
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03753
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF568	Pathway Commons Protein-Protein Interactions	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.2076
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07549
Perturb_7516_KO_TFAM_SRP213924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.55628
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895707
19855078-TableS5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K29636267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00952
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34980742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31853
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19032
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34252
ZNF263	ENCODE Transcription Factor Targets	1.0	null
SW620_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.48828
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NO10	DepMap CRISPR Gene Dependency	1.0	2.28282
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
piperacillin-3763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
yohimbine-6777	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25438
BRD-K88642841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35802
iopamidol-5832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02119
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61209548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75641
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2449
ginkgolide A-4002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.245926
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MERO25	DepMap CRISPR Gene Dependency	1.0	2.76989
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05709
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
flufenamic acid-1420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38089
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K90702609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28463
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.57474
EOMES-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13782363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08415
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4076
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64072266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29756
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45638
BRD-K39692099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6466
FADU	CCLE Cell Line Gene Expression Profiles	1.0	1.56712
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35394
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.815453
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46856
BRD-K09583061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17184
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78789413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30732
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0332
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66095
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0687
amphotericin B-6303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZIC3-20872845-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41911
FLO-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24456
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRC1_BMI_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863939
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2775
hesperidin-2648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899203
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854902
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926233
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.986686
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KOSC-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.87032
PMC4060771-170289.f1.pdf-428-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34482448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36267
CHD7	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.06215
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13962
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42569
Organelle outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.866533
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45375
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68303333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03825
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941974
BRD-K41451401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04036
Perturb_7191_KD_CNOT1_SRP335073	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.73834
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21826560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07087
AC-50-FR41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359428
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395506
SLR25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54201
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K75497233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42678
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52759
BRD-K71298594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01325
NR2F2	ENCODE Transcription Factor Targets	1.0	null
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82312
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10353
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14964
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74882
AB-04-NN16_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232439
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905365
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.830642
BRD-K67661742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10962
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
allantoin-1800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33176
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11012
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41604824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15021
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7809
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAGED1	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.39091
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.14354
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935139
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4477b	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824081
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30192
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56386
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43562
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3993
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-632	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97679
HS751T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90206
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.95559
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977348
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972989
ampicillin-2030	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05802716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10978
CREM	ChEA Transcription Factor Targets	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231104
quercetin-2859	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02759046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24458
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9365
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10037107-JEM_20221755_TableS6.docx-0-IL4-p_D419G-STAT6_targets_in_Jurkats_2_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837266
BRD-K09137343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60273
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20097
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839944
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9420_TUBB_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.691441
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30127
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20721
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842221
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42754852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47939
BRD-A59683007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36812
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880066
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K39192716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13446
cetirizine-2829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00226
Gastroesophageal junction	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
6-bromoindirubin-3'-oxime-7048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882171
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
flufenamic acid-5478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27029
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33974
Perturb_11383_KD_SRF_SRP152523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27323
amiloride-4109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51614
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879979
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gelsemine-2817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48408
trazodone-7410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18927
GSE215351,GSE215794_7_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5987
Perturb_7943_KO_MED12_SRP201365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.77973
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93698
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.41802
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06735
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10669
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48079
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0632
SYK_druginhibition_155_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.39427
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933362
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal recessive nonsyndromic deafness 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
pentoxifylline-7319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C-75-6428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11388_KD_BRG1_SRP261084	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.69849
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HO-1-u-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.04422
BRD-A60076435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16805
N6-methyladenosine-6732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chlormezanone-5697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
EZH2	ENCODE Transcription Factor Targets	1.0	null
pivampicillin-5465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1693	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.35325
neomycin-2066	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8495
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02256
BRD-K40685792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86535
BRD-K07802542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45278
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39257
BRD-K28691459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35146
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60368
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203475
Hoxc13_OE_GDS1890_174_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HKBMM	DepMap CRISPR Gene Dependency	1.0	5.25009
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832957
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05355
clindamycin-7172	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
Perturb_9678_KD_PIAS1_SRP295152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.51714
BRD-K29850806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73999
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857336
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95837
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18107
REST	ENCODE Transcription Factor Targets	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.051
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286158
Fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30982
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37504
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41107
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14211116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15308
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3588
meclocycline-4982	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5140759-NIHMS819001-supplement-supp_dataset3.xlsx-d_GFPoe_vs_CPEB1oe-Table_S3d_APA_events_in_CPEB1_overpressing_HFFs_CPEB1	Rummagene Transcription Factor Associations 2026	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257757
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K31533112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16684
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-28	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.55379
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40209
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41272
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76943
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92955
BRD-K22298558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10081
BRD-K70039231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20246
GSE182680,GSE182683_10_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26559753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01997
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38499
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66085
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895683
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.67452
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07315
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.979219
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.812426
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-common-common_genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_HL-60_and_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22093970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.565
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.02783
benzbromarone-6669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K45762887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41047
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lymecycline-7291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63449
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA6_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01057
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04179
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4772
VAL	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.5398
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY1_upregulated_HEY1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79279
LONP1	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24196
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01831
BRD-K34737616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00049
meclofenoxate-4268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3632
BRD-K89767945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34438
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07037
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3624
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.76505
NCIH3255_LUNG	CCLE Cell Line Proteomics	1.0	2.13969
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DF-53-QT23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395526
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.25436
Acne (severe)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26198
REH	CCLE Cell Line Gene Expression Profiles	1.0	2.10904
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4254
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
451Lu	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.24129
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67081
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831655
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.812483
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09956
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69962
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
creb1_22108299_lung_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.15703
SARS-dORF6_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.22886
clebopride-6311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
boldine-4122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7537_KD_RREB1_SRP265233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.79348
TE-26-XS06_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57105
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09019
demecarium bromide-2773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clomifene-2624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TSC1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24426
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849954
ronidazole-3557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30043
BRD-K45717258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78322
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07917
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6257
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42957
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09998
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25809
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85209
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72168
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20402
bromperidol-2872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1765
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6604
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09328
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nifenazone-2285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
norfloxacin-5985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K98355012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01531
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
aconitine-2776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49128
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25479
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222603
isoxicam-7268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37019305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74788
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
perphenazine-2040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25885
FOXM1	ENCODE Transcription Factor Targets	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.71673
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24525269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21312
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53362
CRCGN015_MCF10A_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05259
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.29947
IRF1	ENCODE Transcription Factor Targets	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65593
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67897
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL1-OVERLAP_GENES_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2531
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.01997
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4747
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39027348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06597
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25665
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	5.37134
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908081
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06976
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64857
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06105
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47006
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	2.25701
flunisolide-2168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10553
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25823
rolitetracycline-6731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.53882
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22421
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10411
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
253J	DepMap CRISPR Gene Dependency	1.0	3.23836
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04691
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.55657
BRD-K64299311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83241
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91754
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72834
haloperidol-983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04397
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6071
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14074
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
brain	HPA Tissue Gene Expression Profiles	-1.0	-0.927519
BRD-K46458719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4547
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.144
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10473
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.44137
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dropropizine-7429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12894
CCNT2	ENCODE Transcription Factor Targets	1.0	null
fusidic acid-2647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3371
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08421
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
BRD-K77638937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77958
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.67209
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86977
BRD-K57356416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28164
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tretinoin-390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9593
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20334
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.40978
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16098
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08916
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.972589
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17016
BRD-K25993054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07191
ATG14	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3670	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-K54134201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06854
SHI1	DepMap CRISPR Gene Dependency	1.0	3.35739
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77261
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Members_of_the_PBX3_regulon_as_identified_by_SCENIC_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20049
edrophonium chloride-5001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isoxicam-7028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863348
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50586
MERO83	DepMap CRISPR Gene Dependency	1.0	2.01597
OVCAR-5	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.17748
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11573
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07939054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05716
indometacin-5468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K34475679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4459
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376478
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
gossypol-2202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.287472
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-102-ZSCAN32_ZSCAN32	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1015 (INTS6)	NURSA Protein Complexes	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1892
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
srf_17591768_igmpos_igdpos_b_cells_lof_mouse_gpl339_gds2805	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.531026
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31947
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39048
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22785
Perturb_10799_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52789
imidurea-5481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93611325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08202
17683608-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52038
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826733
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34807
BRD-K19320442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67379
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diazoxide-5810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE88819_6_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78015598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23323
fusiform gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990713
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15711
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212737
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72501910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0295
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
betonicine-3745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.97363
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ciclopirox-5023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914855
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888796
foliosidine-2201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64245731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14412
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26691
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06084
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24796
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10753
chloropyramine-4414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23663
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834711
Perturb_8820_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.6217
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL1682 (BUB1)	NURSA Protein Complexes	1.0	null
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39449566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17396
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426154
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77969
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A69097282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05258
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3516
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30257
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04896
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18517
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16231
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pyridoxine-2751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UC-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO201	DepMap CRISPR Gene Dependency	1.0	2.11617
9223_TRABD_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.54627
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
clemastine-7485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24997610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07271
BRD-K28950508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62574
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.99986
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51614
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29929
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.41897
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35339
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8338
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60747
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14547
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
verapamil-2009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12172
tetroquinone-4159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FGF23_OE_GDS3361_493_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33869336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3416
CREB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06815
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP63_01_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58575
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26779
sirolimus-362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K25596713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12033
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0416
BRD-K50977435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26707
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70568
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15405
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471181
edrophonium chloride-2019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13604
MECOM	ChEA Transcription Factor Targets	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_7317_Mut_RNPS1_ERP130711	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.91704
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87385
Perturb_8819_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1854
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21049
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-5981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF281	Pathway Commons Protein-Protein Interactions	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33355
PMC8719356-NIHMS1762846-supplement-2.xlsx-cluster_EC2_x_cluster_EC1-ID_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08389
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89328601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78101
GCN1L1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
tetracaine-7473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875458
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926195
PMC3807112-srep03041-s6.xls-E2F1-Gene_Symbol_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48675
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K47326075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67909
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262745
KIAA0226L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19523037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71648
MTF2	ChEA Transcription Factor Targets	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46701
CRCGN011_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0291
KNS81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06295
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12264
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73023
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90053
SSR4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K21937603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31155
HC-11-RK51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254335
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18833
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75453159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5155
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18299
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	2.38237
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29534
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16477
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17702
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332185
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09859
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845783
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00444
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909794
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13895
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26034
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_16602_KO_Alkbh5_SRP125927	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.69541
BRD-K01096898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18861
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5379
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15997
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H-89-6878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964029
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08411
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54903703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19375
HS698T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03254
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9273
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429371
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75426080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06168
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848224
benzonatate-1801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K71040831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23738
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38894
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1298
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04017
KIT_activemutant_55_GSE17743	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.65292
BRD-K97359891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50863
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51777
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13999
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03986
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17215
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nipecotic acid-7296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amantadine-3280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_14099_KD_AHR_SRP154013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.43834
nalbuphine-5820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44344
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5324
hsa-miR-711	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20938
ethoxyquin-3421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the oral cavity	GWASdb SNP-Phenotype Associations	1.0	0.132573
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23382
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826341
STAT1	ENCODE Transcription Factor Targets	1.0	null
ezh2_22267199_heart_lof_mouse_gpl6246_gds4309	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.313433
BRD-K11504463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75898
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33858
BRD-K04441230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65792
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24758
ACACA	Pathway Commons Protein-Protein Interactions	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.9394
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87319
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2319_KD_PRPF8_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47916
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
572_ASCC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.625968
LPS141	DepMap CRISPR Gene Dependency	1.0	2.85433
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86461
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946485
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-2.65594
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6133_OE_Tfeb_SRP157662	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.3367
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68245
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.956
nitrendipine-6464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09775
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56821
riluzole-7365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
azathioprine-2028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12909836-44318_2025_675_MOESM6_ESM.xlsx-DA_E605_PerS1_M1_10_MQ-noMBR_MR-Unnamed_3_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43820045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48711
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60716
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4557
PF-00562151-00-5954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63573
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.17526
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257276
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04444
sulfamethizole-6272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8132
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.955149
BRD-K59130962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22932
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.11709
BRD-K24178822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26379
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61308
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.42393
NOP58	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A52794651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05236
u26684	HPA Cell Line Gene Expression Profiles	-1.0	-0.94742
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45941986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00849
94T778	DepMap CRISPR Gene Dependency	1.0	2.13385
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21279
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41144
POLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25565
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326221
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37462
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2679
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99036206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07832
BRD-K27620386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01773
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01484
HNRNPAB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00452291
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15768
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.687072
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76609
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11726
GSE189941_1_v_0_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16087
MYC-22102868-BL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30677
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16199
Perturb_11380_KD_GATA2_SRP178865	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.6998
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06944
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321977
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.46964
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855842
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0345
BRD-K39179354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1978
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
imidurea-5062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42509
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-MEL1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.87905
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29428
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS81	DepMap CRISPR Gene Dependency	1.0	3.23499
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21255
tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.896535
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969585
Mitochondrial membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77489
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852208
BRD-K25877330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09386
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850671
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxycycline-3479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244225
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77785
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.473
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.092302
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980979
OVCAR5	BioGPS Cell Line Gene Expression Profiles	1.0	1.43249
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3319
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2417
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7937_KO_MED12_SRP201365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.57541
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29474
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231978
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87481
BRD-K31602464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01298
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
16760443-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1612
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-58-RW27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417446
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.265198
BRD-K62102480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28314
NELFE	ENCODE Transcription Factor Targets	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65054381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35899
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20241
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29601
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20153
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7836
PML	ENCODE Transcription Factor Targets	1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95884
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1665
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308206
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91284
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949799
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86888
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84264
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.12971
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13601
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIK3C3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95111937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68155
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0639
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.49
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859765
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841582
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857137
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20966
chr22_50190317_T_G_b38	GTEx eQTL 2025	1.0	1.321
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29561
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24636
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65405
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985329
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42005
Phelan-McDermid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.31607
kaempferol-3579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-A59J-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77663497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23256
econazole-7427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07846
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03681
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0264
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.06418
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.6186
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PU-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09147
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03171
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98986
BRD-K20560768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06105
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.35717
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.953247
ILVBL	Pathway Commons Protein-Protein Interactions	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.596
NDUFS3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.98962
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28753508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57669
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPDEF_01_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.9612
BRD-K63436783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05264
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8904
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
10219_ZNF226_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.579006
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_34_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07981644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52238
CBX3	ENCODE Transcription Factor Targets	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85955
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.909473
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11461
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27071
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
lisuride-5028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
famotidine-2029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ampicillin-5408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983566
SB-203580-6894	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.858558
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74437
NALM1	CCLE Cell Line Gene Expression Profiles	1.0	1.38972
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.954362
heliotrine-4739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.19279
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.077789
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02645
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08954
EMC-BAC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.50464
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20103
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473488
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71468
BRD-K67626097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00884
sulfamethoxypyridazine-3409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYC-22102868-BL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580855
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.931669
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10833
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08456
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41682
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol-5955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sodium phenylbutyrate-363	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62620616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95112
abnormality of taste sensation	GWASdb SNP-Phenotype Associations	1.0	0.463779
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
finasteride-3744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54287
KOPN8	CCLE Cell Line Gene Expression Profiles	1.0	1.59865
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16519
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9899
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06679
tolazoline-1500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59542165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99689
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27213
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55229
betazole-1690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE215086_8_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89438
Gut microbiota (bacterial taxa, rank normal transformation method)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1155	CCLE Cell Line Gene CNV Profiles	1.0	1.34912
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827526
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87505
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0195
sirolimus-1148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52348
BRD-K36795325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10316
valproic acid-1155	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
atractyloside-3435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.762248
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05837079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31587
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21478
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901219
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50288
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1858
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31438
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394474
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99978
Eosinophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.91549
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17055
FANCI	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17657
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14645
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26092
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651048
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58538
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57778236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40255
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49494
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12393
MZ1-PC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.47203
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Plateletcrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HSG	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503012
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85769
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223229
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865378
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midecamycin-2026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66604
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.65667
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
sisomicin-2493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491236
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12632
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19091
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36357
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825223
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15517
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28037
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28814368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18885
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853564
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836263
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.077789
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06412
r1 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14264
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.31953
MET_knockout_249_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78683
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39907
oxolamine-4969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GAK	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.84105
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSRC2_KIDNEY	CCLE Cell Line Proteomics	1.0	3.57021
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0344
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337648
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-641	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.32053
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20225
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915545
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67715
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K36718828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00585
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5292
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10619
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16476_KD_Ripk4_SRP173803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18237
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05367
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03377
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26481
Blastodisc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17532
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6017
trichostatin A-2474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-7.32478
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07472
A549_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145709
Perturb_14525_KO_Foxa2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.8539
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1591
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8752_KD_ANLN_SRP083014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36449
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.897397
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14611
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39195
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88721
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27072
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9032
Prestwick-1085-3554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
wortmannin-1184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nomifensine-1378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNT-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839506
hsa-miR-4288	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	0.920477
fulvestrant-1238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857666
Perturb_11189_KO_Pdx1_SRP252480	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31165
triflusal-2867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81812
HSC4_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.49888
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1412
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30405
lidoflazine-5804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23656
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62499
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203938
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39699
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32223081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6766
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30997
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48784
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WB-82-EL69_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209408
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04994
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6088
NOZ	DepMap CRISPR Gene Dependency	1.0	4.22761
MV411	CCLE Cell Line Gene Expression Profiles	1.0	1.73857
WDR6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22508525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14497
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08787
abnormality of the mouth	GWASdb SNP-Phenotype Associations	1.0	0.123756
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36409
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03153
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7356
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50181
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2309_KD_DHX8_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.34608
letrozole-2916	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-1085-6131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72687
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224328
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20646
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4913
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20257
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7332
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88834
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04625
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0309
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tranexamic acid-6238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.49797
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AC-71-VV28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335739
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC13127299-mmc2.xlsx-FOXM1_kdRNAseq-hgnc_symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23212
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28476
OCIAML2	DepMap CRISPR Gene Dependency	1.0	2.05414
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6155
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889892
zalcitabine-4799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7281
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23382
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00729
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52969
BRD-K21729626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37319
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10669
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905856
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17651
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04959
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.046488
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67252
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.025895
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGS	DepMap CRISPR Gene Dependency	1.0	2.75461
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945361
GP2D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96558
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2158
BRD-K60587793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27699
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99398
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8429
BRD-K95822658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97738
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
K562_TMP195_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202714
sirolimus-1242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364147
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12756
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1348_KD_RAC3_SRP368300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.47095
naftopidil-7331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20939
BRD-K01039605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05015
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926124
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55993
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.826463
BRD-K17128952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09066
Atrophy	CTD Gene-Disease Associations	1.0	1.12668
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7146
monorden-6979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45027
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46989
azathioprine-5627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
prazosin-6475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CE-00-EK89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209442
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06961
BRD-A79097167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02782
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.038978
BRD-K42091424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17206
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98953346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10497
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20307
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980751
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17284
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32437
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.876264
apomorphine-2005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888784
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21492
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62508
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05638
ZWINT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95218317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87091
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96997646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16177
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60014
pentolonium-3676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20497425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19094
CRCGN015_MCF10A_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6978
HMGN3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39772
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.35285
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gemfibrozil-5488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
dicycloverine-1983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
esculin-6310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854815
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65105
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248564
PC-44-DH10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241114
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07463
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67933
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17212
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289652
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05985
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2752_KD_ADAM12_SRP077683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31748
BRD-A14803952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20506
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884483
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00935
KYSE-510	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.34449
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MHHCALL3	CCLE Cell Line Gene Expression Profiles	1.0	1.37973
bergenin-3467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
tinidazole-4548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21401
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.35088
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9067
NB13	DepMap CRISPR Gene Dependency	1.0	4.14841
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04971
Perturb_12337_KD_TFEB_SRP226507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.11475
octopamine-5469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.66154
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14681
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56332068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32221
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08539
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
carbarsone-1313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322474
10244_ZNF260_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.637622
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27929
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67416
PAX5	ENCODE Transcription Factor Targets	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.0074
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29418
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07673
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237965
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50092
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312953
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3648
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0972
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893537
BRD-K01716842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39085
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05523
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81812
valproic acid-1214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38409
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WF-85-JN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28804
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919223
Melanoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	1.33267
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	1.0	null
VKORC1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.543994
D-247MG	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.94439
BRD-K28140275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57354
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15796
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41672
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62492257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25515
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79675
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35181
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0271
disulfiram-1369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
roxarsone-5051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	2.2441
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50081
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994732
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59735
SPI1	ChEA Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55499
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20521
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872885
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.055
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22293
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26924781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04818
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41966
BRD-K44265418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1619
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12413
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76607
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955124
PMC2665242-gkp077_nar-02582-s-2008-File009.xls-Supple_Table3_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901792
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.71184
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3253
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280718
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.464612
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.023
DMS79	CCLE Cell Line Gene Expression Profiles	-1.0	-3.02506
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47488
hsa-miR-4313	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
OCUM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37206
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.88756
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991031
BRD-A57174914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1724
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04956
geldanamycin-1228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-29	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.77231
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.948505
inferior temporal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905675
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279151
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47625
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71748
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840702
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53379620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60828
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39585
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2996
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41834
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27471
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.75732
GSU	DepMap CRISPR Gene Dependency	1.0	2.86811
HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886271
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL3-OVERLAP_GENES_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33253
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24283
HCC95_LUNG	CCLE Cell Line Proteomics	1.0	2.15592
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24758
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203348
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12684
BRD-K46015322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30613
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.544211
triamcinolone-5835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.93056
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952535
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12482
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10605
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938556
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00444
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11437379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06325
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
BRD-K84935293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10138
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.84
JM1	CCLE Cell Line Gene Expression Profiles	1.0	2.16265
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09212
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18262
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50421
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44652
hsa-miR-4743	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73556828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14103
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863251
SLR23	DepMap CRISPR Gene Dependency	1.0	2.68118
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44008
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89989
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.63489
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	1.0	3.19997
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933863
Perturb_1020_KO_Apoe/Apoa1_SRP318735	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.21638
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3716_HGS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.609421
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0846
BRD-K08442552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50334
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890221
WM3772F	DepMap CRISPR Gene Dependency	1.0	2.13152
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930593
dl-alpha tocopherol-4961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
baclofen-6313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27902176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50938
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05627
BRD-K97472167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02916
organelle fusion	GO Biological Process Annotations 2025	1.0	null
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27494
BRD-K60653414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17904
Prestwick-920-5475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408724
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873504
HCC1937_BREAST	CCLE Cell Line Proteomics	1.0	2.01436
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0627
BRCA1	ENCODE Transcription Factor Targets	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.82278
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07383
sulfacetamide-6349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906075
BRD-A68842442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12765
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967398
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.30367
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01913
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78892
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
aceclofenac-7269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27647
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	2.41533
SNU626	CCLE Cell Line Gene Expression Profiles	-1.0	-3.05453
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04193
CAY-10397-7082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K33461572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39984
QE-18-WG07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332602
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09919985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20251
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03343
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10791
GSE116299_6_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
benzydamine-7169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51461946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41439
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.988066
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30868
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92119
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26638
KYSE520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56628
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38642
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP1_Deficiency_GDS1606_765_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
meclofenoxate-2546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
metaraminol-7368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gabapentin-3472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HC-01-FD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.712948
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19897
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prechordal mesendoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8966
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.894811
GA-77-MH38_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208675
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91448
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.97
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212934
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
AMBRA1	Pathway Commons Protein-Protein Interactions	1.0	null
isoxsuprine-1485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16652
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-17-3p	MiRTarBase microRNA Targets	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82387
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU719	DepMap CRISPR Gene Dependency	1.0	2.59452
Perturb_4885_KD_TP53_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859158
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLPI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00500011
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiometabolic and hematological traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.10969
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BD-96-HO33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222266
BRD-K40621788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53015
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34595616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22236
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70388
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46947
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28436
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.72739
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00018
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97614
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.14354
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412257
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	3.61741
fluvoxamine-2913	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
2121_DDX42_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.512889
nifedipine-6006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58377
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14074
PA-15-CP52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252468
JHH4_LIVER	CCLE Cell Line Proteomics	1.0	2.20923
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0803
BRD-K69872823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61515
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388323
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00079
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DZIP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76713298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70229
SE-81-RI20_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298567
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14699
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25944
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.27973
BRD-K26603007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02309
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28478
BRD-K34004579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19367
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05445
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60261
trimethylcolchicinic acid-4202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
proxymetacaine-3113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65773140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.07348
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A265-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-04-PX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402842
BLOC1S4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45427
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1004
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38506
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12991
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.80659
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.196
flupentixol-2643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
conessine-4777	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
20490655-ST3	GeneSigDB Published Gene Signatures	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.26396
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883283
WA-03-IF37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534035
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66542
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23515
BRD-K28034484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72025
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825843
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27932
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22202
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64949
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93171
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09008
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.65318
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K60337657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21395
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08757
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912911
BRD-K73275682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52372
COLO205	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44907
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10119
procainamide-2618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143692_2_v_3_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5599_KD_YY1_SRP259187	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.19068
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1121
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01119
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878768
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26743
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72114
BRD-K91615044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5549
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
PANC1_PANCREAS	CCLE Cell Line Proteomics	1.0	2.22528
6-azathymine-2827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00927
SP1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07306
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04715
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70823
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44735
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3379
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09581
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nordihydroguaiaretic acid-6983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K35288418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87153
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354727
PMC2665242-gkp077_nar-02582-s-2008-File009.xls-Supple_Table3_CTCF-Unnamed_4_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
paclitaxel-640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.45679
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38057
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87685
BRD-K10288935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0063
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7243
Perturb_2797_KD_RORC_SRP066204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.88914
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
NCI-H1573	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23608
Perturb_9681_KD_PIAS1_SRP295152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.82153
atractyloside-7393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K74842791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34572
LBR	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21401
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02137
GSE131649_2_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887171
nefopam-2355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MICOS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16132
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304415
kinetin-6073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10694
ChIP_ZIC3_20872845	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lansoprazole-2967	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06802
napelline-4486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899753
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515247
KAT2A	ENCODE Transcription Factor Targets	1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489285
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.550755
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65748
BRD-K56428170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15383
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85232515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50642
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.405032
OVKATE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64681
BRD-A66369147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18092
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06152
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51959
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08227
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.53858
Fibrochondrogenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863251
chr22_50202217_A_AAAACAATACCCAC_b38	GTEx eQTL 2025	1.0	2.18539
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76196
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48206
BT-474	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.71703
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48717
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04018
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03111
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82578
BRD-K41172555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11572
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66016089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74339
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54036439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80668
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60648
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77372
miconazole-6615	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897239
Autosomal recessive nonsyndromic deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26251
BRD-K78238858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60536
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.30374
norfloxacin-1406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K19085288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00553
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.640972
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	3.23288
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45986
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-5	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.62215
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28367
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53688
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64359
BRD-K30257736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3278
BRD-K32511780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26531
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.33683
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66461
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RORC_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0346
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2547
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-5581	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98594
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.79094
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16288
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35732
BRD-K23560817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78884
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30242
BRD-K53770426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36651
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836847
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31826
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.2121
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98282
scopoletin-3131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28846
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-92-JL46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265647
trichostatin A-3332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.7468
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00485
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mephentermine-3425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88831197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62794
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16288
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73804
Cetirizine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82614
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
noretynodrel-1818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15629
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
verapamil-6287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37406
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96531
BRD-K99416393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15103
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39152
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12789
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915077
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74633
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50097
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18469
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42976
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_SupT1_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_SupT1DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
risperidone-2947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K05509844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80867
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878572
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26846
bufexamac-7413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35711197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37897
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09276
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.838172
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15408
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894103
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36219
RI1	DepMap CRISPR Gene Dependency	1.0	3.09909
BRD-K08308527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10025
BRD-K24659381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0592
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2381
Perturb_11434_KD_SRF_SRP152523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40995
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52854
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01212001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66759
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
u266	HPA Cell Line Gene Expression Profiles	1.0	1.03835
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38273742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04984
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1497
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17412949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4265
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11079511-ir-2023-00162-Supplementary-Table-1.pdf-3-LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967718
KYSE520	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13659
monorden-1219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878154
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07359
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6116
CHP134	DepMap CRISPR Gene Dependency	1.0	5.88489
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09481
BRD-K18488784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27463
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11995
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969597
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08139
BRD-K82508779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06738
BRD-K14124956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28922
FOXP3-21729870-TREG-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26587
BRD-K90138084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14131
spiramycin-3419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.59768
BRD-K28269391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05619
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
baclofen-5414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00049
BRD-K99077411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80065
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586755
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877623
MN-60	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.66363
Ruxolitinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.51
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.41682
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44912
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.0143
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24704
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53116
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30762
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
ED-32-VE54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257455
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.435824
CAD	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53617314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60761
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58001
buspirone-5343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25955
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
azapropazone-7277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.65242
sulfinpyrazone-6230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861466
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.795
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27514
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02302
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83755051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10886
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78297750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04068
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16065
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40602
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6667
PMC8851354-Table_2.xlsx-Genes_reg_by_FUS-DDIT3-Supplementary_Table_2_Genes_significantly_regulated_by_FUS-DDIT3_expression_in_HT1080_cells_adjusted_p-value_0_05_and_log2_Fold_change_1_or_-1_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41549
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18075
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ceftazidime-5473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879469
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF4_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01755
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06393
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339129
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843535
BRD-K51956957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24592
BRD-K82700281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27304
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8135
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839097
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63861
BRD-K71493640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.059
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.912112
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.415751
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disulfiram-2215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58471
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22302
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06198
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947744
BRD-K44339278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56882
PMC8363470-mmc4.xlsx-Strategy_3-KD_CoV-2-_vs_CTL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15629
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7101
propylthiouracil-2837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77498991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5764
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.09181
BRD-K62555617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93215
chr22_50189275_G_T_b38	GTEx eQTL 2025	1.0	1.51534
doxepin-7415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79147587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07826
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16049
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524536
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acetylsalicylsalicylic acid-1377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.06261
PMC5541666__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K64111129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57519
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21439
COLO-829	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.07936
sirolimus-5927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831366
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.04627
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1092	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92125
cyproterone-6806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
222 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38409
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06488
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04114
MCAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00576882
BRD-K82681356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76793
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85955
UTX-26944678-CHIP-SEQ-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.871718
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11307
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K74598339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25301
Perturb_3923_KD_VPS37B_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.50627
PMC11769652-EHF2-12-250-s001.xlsx-Sheet1-ZEB1_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A72515205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08501
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.50711
phenylpropanolamine-5298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12684
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.653
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.034
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06964
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K82842087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16325
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.51201
tanespimycin-1006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89121101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09772
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96250732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1738
BRD-K31897694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13233
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57177
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.056988
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82417
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02279
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1326
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3838
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206001
Cystic Fibrosis_Pancreas_GSE769	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.97739
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858393
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992488
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04292
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70675
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.792
BRD-K97373334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31765
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21401
TE125T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56163
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02769
MYC	ChEA Transcription Factor Targets	1.0	null
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00055
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07743
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06504
OC-71-BZ81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324707
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01911
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957591
lynestrenol-1537	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92978173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16401
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K35171408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24376
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38497
LCLC-103H	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99399
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825875
trichostatin A-1153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15173
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K88278778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19466
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCB000039-7536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00017
BRD-K36726853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07759
E2F4	ENCODE Transcription Factor Targets	1.0	null
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58019
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966015
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390236
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.564655
Lung squamous cell carcinoma_LUSC_TCGA-46-6025-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VC-19-YG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210507
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.6714
midecamycin-5345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15756
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13018
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297987
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxycycline-7195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23427500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35125
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854633
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67744
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32285
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70579
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978688
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57476199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27421
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.90175
vitamin c_homo sapiens_gpl6884_gse16590	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17922
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00922
CRCGN015_MCF10A_48H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06855
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14691
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.093
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09875
REH	DepMap CRISPR Gene Dependency	1.0	3.06235
ALLSIL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36299
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308706
trichostatin A-2904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.887207
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.710449
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UVRAG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
WA-43-MP01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225708
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80489
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12927
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13370005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23107
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40946
nipecotic acid-3121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_8705_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89136
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
methoxsalen-3302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.6568
sirolimus-1646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7408_KD_HNRNPM_SRP010280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.72802
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13071
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03631
Actinic keratosis_Skin tissue_GSE2503	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45735
GSPT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03312
sulfadimidine-3765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27251
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.3816
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84221
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT5A	ChEA Transcription Factor Targets	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898661
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7903
streptozocin-6098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.50869
bucladesine-3483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.47504
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10922
GABPA	ENCODE Transcription Factor Targets	1.0	null
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20341
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849078
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
denatonium benzoate-5480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cetirizine-2468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980198
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.753413
BRD-K35635568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46253
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.6609
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36536
HB1119	DepMap CRISPR Gene Dependency	1.0	2.08841
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36661
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.856956
BRD-K59188100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29648
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07846
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894019
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36174
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16652
OVCAR5	DepMap CRISPR Gene Dependency	1.0	2.09437
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905492
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11931
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45208
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81293
OVMIU	DepMap CRISPR Gene Dependency	1.0	9.24343
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24931
SCO2	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4341
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
BRD-K62072978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30224
BRD-K26704304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11793
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60238606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03645
fluphenazine-1237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98972
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52747
flunarizine-7412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03527
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.27542
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824125
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4758
HEC251	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3266
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08456
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49633
foliosidine-3636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935233
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21839
BRD-K75648723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37724
ARL6IP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26063
ICC9	DepMap CRISPR Gene Dependency	1.0	4.74679
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86605
YY1	ENCODE Transcription Factor Targets	1.0	null
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70433
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2889
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51983
BRD-K86964464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32451
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81997
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336855
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61484
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
T3M4	DepMap CRISPR Gene Dependency	1.0	2.5941
levcycloserine-3870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BRD-K57357721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34051
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33843
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76518
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.864
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900947
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903974
SUDHL6	CCLE Cell Line Gene Expression Profiles	1.0	1.4924
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01775
YME1L1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7437
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67715154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11476
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96843
BRD-K60430317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54938
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35666
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01287
stomach_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.10351
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930258
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3032
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83873
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K39794286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45893
minaprine-1968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59638683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37329
eucatropine-3841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
etiocholanolone-3639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07508
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_SupT1_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989014
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28599
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90122
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.649518
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51313
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28013
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4766
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845427
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63492
flumequine-1429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18057
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12848
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57459
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841776
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24269
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08065
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37515
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00365
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal adrenal gland morphology	IMPC Knockout Mouse Phenotypes	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.51299
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14994
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00961
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886271
BRD-K19731191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65302
TFAP2C	ChEA Transcription Factor Targets	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09354
Perturb_7496_KD_EFTUD2_SRP192094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.1842
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.10412
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86065
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87044635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14279
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78208
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38684
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18099
ethambutol-1981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41706
CUX1	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29254503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01545
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38346
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829464
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D1FED24h_vs_D1FAST24h_259_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14941
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39015
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.066
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05599
BRD-K99127896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88053
Perturb_14114_KD_ATF7IP_SRP156289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.7739
monensin-3443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.988359
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K67150949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41205
SLC27A4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78574
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534429
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878131
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13145
nafcillin-4103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860317
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00999
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE190555,GSE190557_2_v_3_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7203_KD_DHX9_SRP080966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.48183
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00286
MYOD1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32093012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48048
HCoV-EMC2012_0Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34959
BRD-K66838288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46986
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45796
vorinostat-6179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91006
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55709
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24687
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LCLC103H	CCLE Cell Line Gene CNV Profiles	1.0	2.04263
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6713
paclitaxel-1959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52119965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22343
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34071
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.634411
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_267_KO_ADIRFAS786_SRP366780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.74871
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24165
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K56525823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00211
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69147598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68008
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43956
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kinetin-2511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
streptozocin-5836	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38862
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12636
PMC8906867-pbio.3001569.s011.xlsx-HEK_and_SupT1_up_XBP1s_ATF6-S7_Data_List_of_genes_upregulated_in_both_HEK293DAX_and_SupT1DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3051
16651414-Supp3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14942
PMC9288051-13046_2022_2428_MOESM6_ESM.xlsx-Super_enhancers_in_B-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16297
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.43884
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835797
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14783
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80104
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	3.47338
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30324
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06953
GSE190384,GSE190386_3_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218229
Outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894576
OCILY19	CCLE Cell Line Gene Expression Profiles	1.0	2.73005
Perturb_11101_KO_Ern1_SRP110147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.97539
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216757_0_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.588
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17166
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97726
indometacin-7409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lymph node	HPA Tissue Gene Expression Profiles	1.0	0.896811
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588988
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26098
glimepiride-2809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
appendices_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.924259
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
zoxazolamine-5390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pimozide-3178	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
valproic acid-6982	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86065
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
lisuride-2046	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01366
1,5-isoquinolinediol-543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03573
9226_TRAF2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.544069
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.50584
BRD-K24167233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15592
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61912
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21169
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90014
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02442
Perturb_15327_KO_Ifng_SRP067752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.88195
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849511
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378567
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28809
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08881
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2093
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.917434
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25141
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16536
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64886
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
imipenem-5997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40628
BRD-K34181077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51518
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.89081
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01028
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trifluridine-3559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.29001
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23302
NB1643	DepMap CRISPR Gene Dependency	1.0	3.62324
PMC6293073-LSA-2018-00153_TableS1.xlsx-A_KD_Tr_1_3_DNAm-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00547
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCI-H1092	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.16588
BRD-K27824953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1367
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21991
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.880617
WM2664	DepMap CRISPR Gene Dependency	1.0	3.78877
CHD1	ENCODE Transcription Factor Targets	1.0	null
SKMM2	DepMap CRISPR Gene Dependency	1.0	7.01655
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20938
Lung adenocarcinoma_LUAD_TCGA-MP-A4T8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TE-8	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.00243
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04221
hsa-miR-4685-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13887
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581425
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cinchonidine-2772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924726
harpagoside-2935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52205
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.97
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6695
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70277
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03913
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_2_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92468187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38671
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00324
carbarsone-3250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K53639581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10836
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215159
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.95096
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5392
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02615
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3612
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
RNA N6-methyladenosine methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04593
CC-90-EX35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248105
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59791
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40265
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825134
BRD-K95678449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70776
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99978
BRD-K88069191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17972
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46708
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889702
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914333
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41192699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29381
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76804
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.016
BRD-K25165359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76634
BRD-K49345010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13942
iopromide-6842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49947
short insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895264
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00592
clozapine-1229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
km3	HPA Cell Line Gene Expression Profiles	1.0	1.25538
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15457
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03623
BRD-K12702054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66144
GIGYF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16736
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09961
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27699
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86951
BRD-K38692266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45964
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08043579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0816
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39868
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22019
NRBF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.651
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.909237
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89566
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12865
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857069
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02565
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
staurosporine-508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21429
BRD-K88960810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28522
etoposide-5027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40797
BRD-K24907498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06998
Perturb_5916_KD_HNRNPK_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.9586
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836895
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44198
methazolamide-5794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCIH929_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.98177
BRD-K33873762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33839
Spleen	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.29839
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05742
BRD-K91895574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64445
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24838
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11644
UBTF	ENCODE Transcription Factor Targets	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6657
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89331
MELHO	CCLE Cell Line Gene CNV Profiles	1.0	2.43712
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00049
ILK	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33939287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55126
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10793
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981344
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39932
diltiazem-1532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21864149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2652
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFA4	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08304
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12261
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13306
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34162
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05918
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83964
PARVA	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28663
SEH1L	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54459
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00433
NC-52-AG88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541325
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0136
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05513
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933546
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.92191
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.088723
5194442-6558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tetramisole-2489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81812
monorden-5579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.8297
Lung adenocarcinoma_LUAD_TCGA-MP-A4T7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30071505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23743
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A80035237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08194
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48476
Mouselcells	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324346
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58246
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32924
STAU1_DELETION_GDS3370_56_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74522958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33654
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24603
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15236
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04625
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW156	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.39539
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16527
BRD-K76492619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81636
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05777
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61099
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6704
cdkn1b_18180298_3t3_lof_mouse_gpl1261_gse9161	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.788156
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10593
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41824
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969827
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16457
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
LY411575	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
0317956-0000-3858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05576
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.09531
PNKD	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09274
mephenesin-3675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_9683_KD_PIAS1_SRP295152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.1545
BRD-K01263144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03216
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866543
PNU-0230031-3632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02142
hsa-miR-647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.05664
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406534
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43816
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905063
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418972
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863964
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11519
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K26051127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02036
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02296
abnormal adrenal gland morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_6794_KD_PAF1_SRP060227	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36002
AA-72-JP86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328489
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951734
BRD-K26570871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50121
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06302
sulfamethoxazole-7366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2327
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87080934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40043
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308227
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K65933652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45074
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31709
memantine-2934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920188
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04568
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15178
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909559
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04761
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846238
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7728_KO_MED12_SRP201365	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84548
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47626
GSE111247_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
antimycin A-1414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18836
SIX5	ENCODE Transcription Factor Targets	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.659221
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45482
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926428
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92913380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19992
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
difenidol-7447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mitochondrial membrane	GO Cellular Component Annotations 2025	1.0	null
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39141
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SSR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12384
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.97569
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF382	DepMap CRISPR Gene Dependency	1.0	2.19095
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07048
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877762
TF-77-DW08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307485
BRD-K44445002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17768
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.44388
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52104866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03508
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8629-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76420749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14253
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933594
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3789
BRD-K72872864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3396
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2327
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16889
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543315
POLR2B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K75410936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06397
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33215
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.49123
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2539
GSE144484_0_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
786	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.3997
BRD-A42030853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05136
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35536
ARAF	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80025
FOSL1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06746
dextromethorphan-6300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMV-II	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.87019
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88202
BRD-K31939603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03914
verteporfin-3556	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14247_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.32743
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30214140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60997
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890613
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00707
Alcohol poisoning_Pancreas_GSE3311	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.26373
BRD-K47366416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12928
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39679
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19351
HE-80-BQ08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23673
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33608
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1616
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7279
pergolide-7434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.48922
5155877-6544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.92181
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76728
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0792
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.620019
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489561
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955124
hsa-miR-138	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395077
Perturb_2322_KD_RBMX_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1257
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcaine-3010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72098698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21282
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876478
BRD-K32506050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9875
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05318
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
wortmannin-506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65564
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.29344
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.95221
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899107
Perturb_5387_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.59244
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95352
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834082
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906005
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38196
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7425
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9585
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08976
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.31722
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907307
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.36965
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50215
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.97015
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81997160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28275
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867002
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6787_KD_KRAS_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.50027
amrinone-6826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.35418
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919223
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77995
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.16192
Human - Lung v1 - L2 - Intermediate Monocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
corynanthine-2786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
smooth muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.973674
CAMA1_BREAST	CCLE Cell Line Proteomics	1.0	2.8452
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24664
GSE190384,GSE190386_1_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01225
diethylcarbamazine-5485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27567
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93961
SW626	DepMap CRISPR Gene Dependency	1.0	2.94633
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
altizide-6829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05339908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76681
Pheromone shutdown, TraB	InterPro Predicted Protein Domain Annotations	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.49127
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10781609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10332
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45796
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937715
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.521
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
trimethadione-2486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03435
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07554
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71655
TCF3	ENCODE Transcription Factor Targets	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360095
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918169
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0226
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984669
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69564
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	2.25234
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95182
BRD-K16641781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70361
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905779
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.13539
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63374
GSE129772_2_v_3_runx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06599
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LN382	DepMap CRISPR Gene Dependency	1.0	3.96547
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72114
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48446
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.26705
Marshall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
BRD-K41876347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78416
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971467
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30781
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870252
LY-294002-361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46074
Eosinophil count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0301
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980301
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21429
Perturb_17479_KO_ALPG_SRP277076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36661
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909794
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17125
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18472
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.443975
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869396
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48413
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XRN2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-198	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A50287893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27608
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML1-OVERLAP_GENES_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.980406
BRD-K41875112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40429
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fusiform gyrus, left, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873822
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-3993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10256
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42515
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07091
STUB1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73467
stachydrine-6805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.33306
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4947
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08115
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51752
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K66324291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12954
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22854578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05381
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965446
Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41436
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228894
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27168
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65441
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54181
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K89935890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81427
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18368
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874859
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956461
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44705
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93406
AC-50-FR41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238776
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028132
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.564737
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A08363225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62615
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2954
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09746
BRD-K22957824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9437
SKOV3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.47022
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20735575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28427
A673_BONE	CCLE Cell Line Proteomics	1.0	4.8052
GFI1B	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAUS5	Pathway Commons Protein-Protein Interactions	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5323
Perturb_10125_KD_ACP1/APC2_SRP061848	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.30174
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18339
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721709
Mitochondrial outer membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CNNM3	Pathway Commons Protein-Protein Interactions	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677319
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1681
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23666684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39989
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3898
BRD-K35616138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43834
parahippocampal gyrus, left, bank of the cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94593
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48904
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15809
podophyllotoxin-5841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61024
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948994
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28973
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50823
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.96
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39349
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849461
BRD-K99028283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01127
BRD-K36393312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08681
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6213
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04133
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375269
Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04163641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03918
DOORS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.98023
BRD-K46269666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85628
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65173
MET_knockdown_254_GSE38343	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.05661
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6572
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895068
BRD-K06318195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25828
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26656
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82734
raloxifene-202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03491
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04918
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43175
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3953_KD_NCOR1_SRP319239	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40011
colforsin-783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
J82	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.11869
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10070455-41598_2023_32568_MOESM3_ESM.xlsx-Genes_AA-genes_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
butoconazole-6288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4881_KD_TP53_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.909566
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914034
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47865
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUP-HD1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.46875
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71844
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49576
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974937
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27103
gallamine triethiodide-1375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_down-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.02815
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.454273
Autosomal dominant nonsyndromic deafness 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272946
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60375
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36418
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26435
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1868
BRD-K04358482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79013
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23632
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04461
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26138
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36215
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45316
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38155
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35435
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875043
articaine-7272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.12227
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29398
flecainide-3418	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPM1	Pathway Commons Protein-Protein Interactions	1.0	null
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	3.99175
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91698
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09026
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26414
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07274638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17351
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
fulvestrant-4462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_11073_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.61077
BE-82-TS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207556
PMC8326438__F10	PFOCR Pathway Figure Associations 2024	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.840419
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.738602
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35772
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06016
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870394
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05851
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT1080	DepMap CRISPR Gene Dependency	1.0	2.04623
BRD-K65438558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32686
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825325
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880576
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14141
SAP30	ENCODE Transcription Factor Targets	1.0	null
DA-10-HD17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201769
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15756
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64739
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00576
BRD-K21660570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56396
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80256
NANOG	ENCODE Transcription Factor Targets	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7199
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12941_KO_UBE2T_SRP312031	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01424
troglitazone-370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98409
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923395
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.692734
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872179
GTEX-PWCY-1026-SM-48TD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941608
BRD-K12640996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30882
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48451
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248231
ABCE1	Pathway Commons Protein-Protein Interactions	1.0	null
CDKN2A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225218_9_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null