association	dataset	threshold value	standardized value
BRD-K96778009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43195
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5186
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04003
BRD-K13804959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22957
BRD-K74862734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19958
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K05678583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0651
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29668
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.51
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microspike	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99884
FLI1	ChEA Transcription Factor Targets	1.0	null
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.23933
SNU5	CCLE Cell Line Gene Expression Profiles	1.0	1.37441
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_UP-Ensemble_gene_ID_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.77816
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5979
WM115	CCLE Cell Line Gene Expression Profiles	1.0	2.25166
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32240435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19624
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20161
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10734
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08711
KARPAS-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977944
BRD-K33400588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08217
BRD-K10459972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17237
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25588
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42246
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17011
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963635
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19344
BRD-K72561299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45269
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07775
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-0.890586
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29002
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214556
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8266
Interferon Signaling	Reactome Pathways 2024	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61333
BRD-K41412255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55835
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5503
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13587
Acute megakaryocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3987
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-2.19614
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0668
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10536
BRD-K47337578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66351
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K79481905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55154
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38357
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827539
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13829
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51285
SN12C	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49761
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846265
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K84769529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66193
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866875
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861719
hsa-miR-4314	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84115
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17907
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97512
BRD-K26214026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07507
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.80819
BRD-K48670593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70619
Perturb_354_OE_MITF_SRP298756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58095
SW620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2888-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19315592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74861
BRD-K03923461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28728
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8259
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8057
MALME3M	CCLE Cell Line Gene Expression Profiles	1.0	1.53916
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71622214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37159
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5065
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
BRD-K49208610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22966
Lung squamous cell carcinoma_LUSC_TCGA-22-4601-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50009
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30167
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8696
BRD-K47030799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11479
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.97982
BRD-K67632894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24455
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2015
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24658
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30787
KPNSI9S	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52736
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25864
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870727
Auditory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12858
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874067
BRD-K06219419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14922
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25966
BRD-K72379955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01529
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50588
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921079
BRD-K19133474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06541
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07061
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8009
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02435
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1467
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43664
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8569
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51T-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79213964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21573
GSE152699,GSE152723_0_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05013
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17331
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7335
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85051
Immune System	Reactome Pathways 2014	1.0	null
BRD-K46890865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07707
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BmN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.26817
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.06125
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59782
hydralazine-3621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K24393110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61569
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22092
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12726
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974528
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
homatropine-5477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.784
KOPN8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71065
solanine-4166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866108
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01493
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23028
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21191
UACC62	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
786	BioGPS Cell Line Gene Expression Profiles	1.0	0.827881
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55075
BRD-K51454545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45012
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2352
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.33922
BRD-K44403120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27881
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29002
EPHB2_drugactivation_228_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.71809
Pleural mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894099
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25864
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61193
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00941
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
COLO704	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.38235
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41343
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54917
BRD-K36021765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86046
BRD-K57014767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36664
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11031
BRD-K41731469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36315
CREBBP	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42628
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3180-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
IGF1R-20145208-DFB-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K40078199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12106
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.553204
BRD-K01723566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05917
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11076
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Interferon Signaling	Reactome Pathways 2014	1.0	null
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00894
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02994
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930785
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36733
BRD-K39397248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06144
BRD-K10301055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.095
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0522
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99497
Kibra-Ex-Mer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0366
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980867
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FW-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4587
PMC7793767-Table_2.docx-1-Downregulated_genes_in_the_pancreas_of_AA_vs_controls_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861104
BRD-K57349002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83905
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Intraocular pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.21549
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53817
AC-49-NG46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20147
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	1.46638
BRD-K51898276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53012
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4382
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18638
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94582
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02983
hsa-miR-3675-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06276
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09188
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59085
YD38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05022
skin	GTEx Tissue Gene Expression Profiles	1.0	2.18987
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60364
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952269
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31894
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48661
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3774
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	1.0	1.92904
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990691
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03562
BRD-K58155058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10559
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-188-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Facioscapulohumeral muscular dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19846
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
BRD-K23674935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2056
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00132
496100534_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22524
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
U-138MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1373
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2248
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6346
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62205
UACC62	CCLE Cell Line Gene Expression Profiles	1.0	1.59124
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE450	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11521
baclofen-2036	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0388
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.37991
AR-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
anterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07214
PAX5_OE_GDS4978_547_human_L428	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91199
BRD-K15502859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05642
BRD-K12067186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64324
BRD-K77797589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32177
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.98995
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.10904
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04539
6-chloromelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2047
BRD-K11641139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1005
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ParietalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16533
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24887
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.58116
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41927
BRD-K51974360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9558
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03428
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02711
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65326
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62827
regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
gliquidone-3126	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Congenital nongoitrous hypothyroidism 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0234
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2731
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.24897
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13225
JVM-3	GDSC Cell Line Gene Expression Profiles	1.0	1.68735
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53845
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05907
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949905
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44687
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Feeling fed-up	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
JA-46-LK88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486864
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4846-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.452
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12051
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04065
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41674016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26041
TE11	CCLE Cell Line Gene CNV Profiles	1.0	1.52691
BRD-K50563598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36207
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
Ppes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.92784
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31141
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80857
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2023	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	1.0	1.36513
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46897
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2516
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-3.51098
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884513
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5258
19190338-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04103
BRD-K58138729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26481
ERG_01_216	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.19784
ethisterone-2366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9693
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.29901
BRD-K39561340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36364
6-bromoindirubin-3'-oxime-7044	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9091241-41598_2022_11720_MOESM2_ESM.docx-70-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859634
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3861
BRD-K47756270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85846
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952269
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32432
NB14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K99302735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07019
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0264
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL5	CCLE Cell Line Gene Expression Profiles	1.0	1.55862
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K80568112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30807
HCC38	CCLE Cell Line Gene Expression Profiles	1.0	1.64684
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KM-H2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6268
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3439
BRD-K27401646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54904
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94306
PMC5323140-oncotarget-07-65090-s002.xlsx-DUX4_ONLY-Gene_symbol_db2db_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Cytokine Signaling in Immune system	Reactome Pathways 2024	1.0	null
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9216
BRD-K72253829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07205
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	4.80716
cetirizine-4231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51003626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54973
BRD-K90702747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13326
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913862
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03117
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67793
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.859452
Facioscapulohumeral muscular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61798
N6-methyladenosine-2626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21212
hsa-miR-943	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
SYK_knockdown_280_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.51041
KP-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40065
BRD-K73872184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65244
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7659
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.7572
AR-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06388
BRD-K67666705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75511
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73268
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85779
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69569
BRD-K18109695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6098
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1763
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0222
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	3.40789
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
fisetin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19832
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37927
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.53092
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10952034-mmc3.xlsx-Table_S2-Table_S2_Pooled_shRNA_screen_analysis_to_identify_genes_selectively_required_for_the_proliferation_of_the_cells_with_the_highest_MYC_signature_score_Related_to_Figure_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4776-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Interferon gamma signaling	Reactome Pathways 2024	1.0	null
AR-21909140-LNCAP PROSTATE CANCER CELL LINES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.1637
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838627
NCI-H250	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LU-134-A	GDSC Cell Line Gene Expression Profiles	-1.0	-2.56189
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
SNU840	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10907
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968137
sitosterol-2912	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hep-G2/2.15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11611
Mulibrey nanism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	2.10772
BRD-K51937785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12238
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.20344
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2477
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960141
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
L428	CCLE Cell Line Gene Expression Profiles	1.0	1.72428
Pleural mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
doxycycline-5838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH196	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12693
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976466
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885189
LXF289	CCLE Cell Line Gene Expression Profiles	1.0	2.13842
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2757
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05054
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00965
BRD-K68459574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48628
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45535
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.21905
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04248
BRD-K40894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29658
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35794
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9961
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40653
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19611
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861719
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.47524
WM-115	GDSC Cell Line Gene Expression Profiles	1.0	2.11513
pituitary	GTEx Tissue Gene Expression Profiles	-1.0	-0.890586
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47502
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0364
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23327891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49988
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K25269762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29257
BRD-K97335870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05931
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905393
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61737
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02994
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13474
hsa-miR-3617	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861719
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54505
GATA1	ChEA Transcription Factor Targets	1.0	null
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.5199
Lymphangioleiomyomatosis disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
BRD-K23954220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28353
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28607
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57181
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.933617
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04265
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97761
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.3978
BRD-K77520720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11482
BRD-K72066653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27691
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
BRD-K87358945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29151
josamycin-4631	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3663-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1604
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27414
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12749
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K46494135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28306
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202007
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00144
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40007
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
8505C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85765
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90549
BRD-K70581786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12306
amiloride-3990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-323b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HT-144	GDSC Cell Line Gene Expression Profiles	1.0	1.52198
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5128
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02955
AR-21909140-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0973
NALM6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17294
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46297
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16269
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76228
BRD-K73475697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81959
BRD-K88195243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07662
RVH-421	GDSC Cell Line Gene Expression Profiles	1.0	1.58686
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200194
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46827
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5555
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6939
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CP67-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.6383
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32964
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3736
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838558
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52709
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15645
BRD-K77808555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18784
BRD-K47874568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60958
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13131
BRD-K59045095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5363
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28863
ZNF665_01_129	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.72542
BRD-K74823284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30383
Shs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53924
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82706
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16243
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8971
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.89582
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33005
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53966
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.71294
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829922
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05337
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2516
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05149
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55895855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51072
BRD-K95895516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72504
valproic acid-4438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45635721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70578
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9495
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24903
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02573
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2922
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999506
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921079
cinchocaine-4068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLR26	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16045
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941401
SNU869	CCLE Cell Line Gene CNV Profiles	1.0	1.40475
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872216
BRD-K71296038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12321
NCIH510	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55625
Pleural mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.834
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.37693
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1354
Rd	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.348
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37221
Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB1_KD_GSE50532_657_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74034
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01371
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.699352
BRD-K77958314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02297
MFH-INO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9199
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41929
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.934216
HS600T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20916
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58644
BRD-K79103937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77366
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
hsa-miR-4721	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K58017833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11922
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8393
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40868
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19087
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01456
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9531
EE-99-ZM45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.359056
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05222
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.01923
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05006
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
COV434	CCLE Cell Line Gene Expression Profiles	1.0	1.5214
RUNX1	ChEA Transcription Factor Targets	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5403
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6941
molecular_function	GO Molecular Function Annotations 2015	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96091
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240404
BRD-K55160477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70816
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41059
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31776
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13225
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7202
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905592
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01606
BRD-K26393435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14028
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8218
SNU1033	CCLE Cell Line Gene Expression Profiles	1.0	1.80557
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.586708
BRD-K90787403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18702
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0989
Lung squamous cell carcinoma_LUSC_TCGA-43-2578-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45200389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37407
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39468
BRD-K70941976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21436
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4245
HCC1897	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66629
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970397
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9904
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.41549
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66X-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929922
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.82127
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94862255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72359
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49562
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.592826
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15866
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18159
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05725
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
oxybuprocaine-3996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04901
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00165
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54859
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44847
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3755
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830479
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25864
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71978
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33249
hsa-miR-802	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K54028343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38283
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15864
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8822
BRD-K45056520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3421
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53488
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6698
MPP89	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6531
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23404
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892767
BRD-K01312966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73608
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.50774
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9868
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967224
Perturb_8901_KD_STIM1_SRP128928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.17939
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2503
cation binding	GO Molecular Function Annotations 2015	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31937
BRD-K35635390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40045
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
BRD-K31330911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97218
BRD-K46877890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36798
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-211	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62078
BRD-K49681465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38266
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10557
hsa-miR-4303	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02094
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09344
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.904312
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09575
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90129
BRD-K93791165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34021
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10079
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3244
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
metamizole sodium-3754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06939
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07451
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858669
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3936	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13516
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5398
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960141
Urinary metabolite levels in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	7.3
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9875
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19701
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7531
hsa-miR-4762-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5077
ELF5	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56076713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16617
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62615
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14187
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5038
COR-L95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE240386,GSE242143_1_v_3_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15844
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27398
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	1.69869
SMAD4	ChEA Transcription Factor Targets	1.0	null
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64653
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRAS.LUNG_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4741
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.85376
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.57084
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848179
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21912
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27956
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999506
hsa-miR-3196	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hsa-miR-4418	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40197
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86368
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5214
BRD-K14392619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06344
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202871
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26140483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36037
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55238630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73537
hsa-miR-633	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89088
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	2.07462
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.09799
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.42345
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912292
HSF1_KD_GDS1733_757_human_HeLa cells - 4 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898802
LNZ308	CCLE Cell Line Gene CNV Profiles	-1.0	-2.32343
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3135
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14154
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
BRD-K39140255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77023
NCI-H1838	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15179
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4788
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917672
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33012
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3683
BRD-K33986892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25922
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62046
BRD-K56161905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05957
GSE240386,GSE242143_8_v_3_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11459127-pnas.2406837121.sd04.xlsx-Sheet1-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9386
Cytokine Signaling in Immune system	Reactome Pathways 2014	1.0	null
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27567
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.978474
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5415
CW2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62375
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34881
nomegestrol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11748
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3083
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55164
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6567
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829399
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37721603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09958
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13664
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51104
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63754039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01564
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8111
Perturb_12661_KD_RAB7_SRP017435	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.20844
HS939T	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
H3K9me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20748
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LEF1_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09006
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39056
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201102
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92554
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0355
TE15	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.49927
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
BRD-K26481999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29436
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12252
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09854
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27296
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46401069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36137
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.68643
ZNF708_01_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.99791
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13527
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44569
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Retinal telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1879
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.14068
KYSE180	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60956
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4651
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.50428
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.309
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
kawain-3670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221266
TFAP2A	ChEA Transcription Factor Targets	1.0	null
A1207	Achilles Cell Line Gene Essentiality Profiles	1.0	1.36184
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48564
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12858
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07313
BRD-K97886487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03949
RNA nuclear export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885545
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.876721
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8002
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K03287885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5867
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.0318
hsa-miR-506	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41768
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24768
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-LEF1_UP_V1_UP-Gene_name_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
Ruffle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
BRD-K64039518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23241
bretylium tosilate-6674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960141
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25864
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12202
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2497
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89891928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09083
SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19511
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06605
BRD-K57022684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17453
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35197
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.968953
MKN-45 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K76175734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23977
BRD-K82674931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07269
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05563
BRD-K60161601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15542
demeclocycline-4728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27304876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00152
CA-72-UL91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277331
HGC-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
lobeline-5784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52202153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05735
PMC9294202__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04042
g2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K72519034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00855
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.890586
BRD-K60587793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06213
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17842
BRD-K05886700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21212
BRD-K90697690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9172
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34692
BRD-K58336011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24158
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39237
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
L-428	GDSC Cell Line Gene Expression Profiles	1.0	1.92771
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.890586
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13363
BRD-K71368065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11396
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.982243
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Interferon gamma signaling	Reactome Pathways 2014	1.0	null
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.9728
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K13839731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32887
BRD-K39206254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13172
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.55008
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4232
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S1-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67989
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3736
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6_01_50	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35122
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K92372829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3177
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28182
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827124
BRD-K78618254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0192
BRD-K22691925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29388
Detroit-562 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08249
Chromosome 2p16.1-p15 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1268
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2061
BRD-K49207204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32654
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73228
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.724678
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88992
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824861
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97929312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24225
U-251MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
AM38	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3759
NCI-H1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.12439
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64511
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9011
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61322
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.7994
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03184
Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Split hand-foot malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
TOV112D	CCLE Cell Line Gene Expression Profiles	1.0	1.67019
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.217
BRD-K85110576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96084
BRD-K74842791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58709
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05449
hsa-miR-105	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849167
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	1.0	3.00043
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833222
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19382
BRD-K44932450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25522
BRD-K17421394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10926
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854485
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87945
HUO9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65367
LB996-RCC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999506
NEC8	GDSC Cell Line Gene Expression Profiles	1.0	1.79267
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13225
NCI-H1092	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57059
BRD-K96183125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20259
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861104
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898872
BRD-K76691746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85593
Facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35629
hsa-miR-3180	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09308
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3249
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827841
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.50165
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54964687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26458
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07914894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09797
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04081
Perturb_234_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4087
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05431
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22383
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0269
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12175355-41065_2025_476_MOESM6_ESM.xlsx-Sheet1-Supplementary_Material_3_Top_10_upregulated_and_10_downregulated_KLF4-related_DEGs_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4001
ESS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.12231
BRD-K43025624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35048
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25927
BRD-K48436333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37734
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96846
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0125
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35479
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23028
Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09209
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	-1.0	-2.19721
fluphenazine-4461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20878
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.37463
Sensorineural hearing loss	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
BRD-K26559753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03292
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68753
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11616
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.64434
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07314
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.41929
HL60	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.27549
Inner ear disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.503
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25414
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09188
BRD-K56285711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72254
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48857
RS411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12834
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872494
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36967
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04454
BRD-K17416171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64958
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4103
BRD-K49391713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56562
BRD-K47926785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32186
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.54587
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47545
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.73307
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29668
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2302
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9246
OTX2_01_268	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.6263
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829305
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39237
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01202
bae1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88715
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.934294
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84357
hsa-miR-1193	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37689
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80206
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11508
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.05879
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50843
BRD-K06320746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07949
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39863
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.40918
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.39302
DU-4475	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.15179
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL851	CCLE Cell Line Gene Expression Profiles	1.0	1.46406
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68627
BRD-K40332193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71642
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.83293
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.663
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19099
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2011
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
15489324-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1438
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34275
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4147
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.951703
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54873
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.46944
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24379
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957923
BRD-K96170115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12119
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15938
Daoy	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63166
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2721
NCI H23	BioGPS Cell Line Gene Expression Profiles	1.0	1.10412
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832163
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872216
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5947
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200203
AR	ChEA Transcription Factor Targets	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44352
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HT55	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05331
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913584
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.85104
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.67914
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6
AML193	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.346
niridazole-4621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	3.27854
CTCF	ENCODE Transcription Factor Targets	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.43979
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221003
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999506
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859634
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-641	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74207
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.722123
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04456
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278724
icSARS CoV_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5263
BRD-K99377541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20149
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93886
Immune System	Reactome Pathways 2024	1.0	null
BRD-K87275815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96877
BRD-K58791506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49839
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	2.04547
Prestwick-864-3333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.342
BRD-K98018160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24526
BRD-K50149147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8668
hsa-miR-3143	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.20157
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01599
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3711
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
viomycin-3541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02237
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861719
BRD-K40264914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50135
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.933506
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A63590986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07695
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21872
MALME-3M cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
BRD-K31866446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65872
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01913
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.36413
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8654
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09042
mesalazine-3584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-LGG_MYB_L1_deletions-Unnamed_2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88802328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31679
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.869025
BRD-K52938793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27858
hsa-miR-3161	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19236
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51635
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36298
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19642
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37918
LN235	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73073
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-2355-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K49384706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13783
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0871
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.06859
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37486
PMC5446900-NIHMS72240-supplement-Table_S1.xlsx-Table_S1-Table_S1_Genes_differentially_expressed_in_human_primary_myoblasts_upon_ectopic_expression_of_DUX4_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43992442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78017
LNCaP-Clone-FGC	GDSC Cell Line Gene Expression Profiles	1.0	1.46865
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02994
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15371
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03117
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9407
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29117
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80414
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861104
BRD-K51061297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2222
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100544_PCx_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66617
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100429_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19694
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41714444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46776
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206967
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87448
RPMI-8226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-124	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3738
hsa-miR-204	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27414
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47037
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4773
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4679
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39417
ETV1_01_179	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.97496
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6889
BRD-K02374169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58925
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0267
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48261
Zinc finger, B-box	InterPro Predicted Protein Domain Annotations	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919211
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43527
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0311
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14907
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894099
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.2274
BRD-A71880598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14318
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20411
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45294
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01606
5637	GDSC Cell Line Gene Expression Profiles	-1.0	-2.11798
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35578
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952269
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TE10	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30369
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.784775
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2975
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.524
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20591
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00669
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83567669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12854
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25842
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7214
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202188
BRD-K27011412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25834
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23407
BRD-K42968343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00275
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06559
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.40983
PMC5056720-pone.0164535.s001.xlsx-AR-DE_genes_with_KSC_p-val_05-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55489373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12968
KYSE520	CCLE Cell Line Gene CNV Profiles	1.0	1.57762
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58242
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66987
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883013
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HA-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978792
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82706
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31362
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8865
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00064
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.42136
hsa-miR-3591-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983936
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PANC-03-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84851
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9839
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20411
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34308
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4816
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
BRD-K78098006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0127
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.8208
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K16432886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05268
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54404
Rhabdomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
U251	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46534
BRD-K39573478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34854
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.33239
BE-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.203
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NJ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01362004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01683
BA-46-RB17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269332
PMC4333416-supp_gku1375_nar-02461-x-2014-File012.xlsx-AR-reg_genes_imapcted_by_siPIAS-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34761198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04162
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32792
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52239
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09529
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
SF172	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83405
parbendazole-3799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89143
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
OVCA433	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Facial hemiatrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
BRD-K60692685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43774
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.192
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	2.60006
BRD-K72488042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2617
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857774
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70905
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22549
B-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46395
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.61549
BRD-K73573019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05049
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44916
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.858439
BRD-K44936922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38949
clioquinol-4663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RVH421	CCLE Cell Line Gene Expression Profiles	1.0	1.8962
Moh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42921
BRD-K64748422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.2936
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-0.890586
BRD-K71015709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26239
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873498
BRD-K62841356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30766
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34979
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.43363
Lung disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.313
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.072
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5141
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3623
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.75069
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	2.06998
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.056284
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04539
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22274
Calu-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84407
BRD-K52838863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72829
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13013
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6102
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K58670847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92008
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920444
BRD-K74789550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14676
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.256
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45013226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90277
BRD-K55256232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11683
BRD-K20724649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45797
BRD-K49875070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50239
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2149
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26362
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990641
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41929
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	GDSC Cell Line Gene Expression Profiles	1.0	1.97757
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
diflorasone-4158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57242481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21792
HT144	CCLE Cell Line Gene Expression Profiles	1.0	1.74264
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16721
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11629
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200707
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5403
496100313_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5138
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207408
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12896
intracellular	GO Cellular Component Annotations 2015	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.7247
BRD-K59626557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21345
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43664
Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr11_55248688_A_T_b38	GTEx eQTL 2025	1.0	2.13898
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849167
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null