association	dataset	threshold value	standardized value
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3442
CRCGN011_HEPG2_24H:A12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3693
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4207
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.505
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73342
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9793
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.143
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2614
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.277
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9124
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3579
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2444
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99155
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3364
CRCGN008_HEPG2_24H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18985
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0053
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1674
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62738
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4466
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.415555
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9219
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3684
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8701
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12422
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8305
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.9977
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7557
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7404
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99881
GSE135350_3_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.1491
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2051
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3444
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7651
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5031
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.32523
CRCGN016_MCF10A.WT.HP_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30606
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8846
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8623
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98015
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8876
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.61636
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5202
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3676
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5759
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0372
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.5098
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30522
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.14
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70328
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229376
CRCGN017_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02505
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9544
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.29506
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16265
PMC5446900-NIHMS72240-supplement-Table_S1.xlsx-Table_S1-Table_S1_Genes_differentially_expressed_in_human_primary_myoblasts_upon_ectopic_expression_of_DUX4_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.068
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2657
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0968
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16237
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Basophil percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.517
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3347
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7048
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19769
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.644
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06903
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9494
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.976
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9917
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7304
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4418
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0613
AA-99-HG96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259166
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.89626
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11104
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57563
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8036
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1034
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5474
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2025
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1614
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.7781
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8289
retromer, cargo-selective complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9212
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9409
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3606
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6109
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64933
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06239
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4772
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3856
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.1679
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7882
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4731
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5609
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8736
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2054
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.834793
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9318
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2595
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4049
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1658
NFIA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.036
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7714
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69055
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4615
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4391
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27571
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09978
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6867
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38505
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1132
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.925
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23574
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07215
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5902
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4575
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72392
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51993
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6746
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0611
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04815
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6808
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.42731
Apocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3156
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9084
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.993
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2761
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1378
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8441
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3374
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.46025
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.43641
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21946
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3729
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.632
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7238
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.84396
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2502
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6716
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3889
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63052
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.316
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1494
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.7763
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.532
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0399
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8636
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2187
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3538
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0238
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.745
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.219
CRCGN016_MCF10A.TP53.M_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01638
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7801
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.409
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15035
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0862
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.593856
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.413158
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2285
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1105
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3539
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2668
DD-61-DY35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.459697
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8378
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4168
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21295
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4268
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6656
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37516
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61725
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01775
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7571
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3003
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1297
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2997
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91527
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73421
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4994
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8764
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0755
intermediate-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.516
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07652
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09928
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0314
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6455
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6611
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8521
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6667
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9255
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.113
BA-06-RE84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219899
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2126
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1915
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2707
GSE161170,GSE161268_0_v_2_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6468
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4191
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1578
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17269
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.75428
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2387
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4348
MF-81-RJ18_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206056
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4562
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353461
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7212
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71975
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8066
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1123
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1301
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5947
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6844
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18746
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6822
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91225
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.943
CRCGN015_MCF10A_48H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22689
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7421
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3321
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3904
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2276
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5883
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5936
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4019
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7839
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4595
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94311
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49797
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6111
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10983
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7227
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4408
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3466
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3083
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4166
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3772
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9699
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09363
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87695
PMC7880901-NIHMS1649581-supplement-2.xlsx-DESeq_V7_1_and_3_vs_Ctrl_1to2_f-Table_S1_List_of_AR-V7-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02901
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.738
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.212
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0197
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1642
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1616
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23833
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02344
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92555
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256799
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82575
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26348
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84369
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5424
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2852
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2955
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2413
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59915
CRCGN015_MCF10A_48H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06709
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27336
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9356
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3463
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81445
CRCGN014_HEPG2_3H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13573
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0631
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.9203
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0526
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48361
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6602
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6329
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.476
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0879
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4521
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4862
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1071
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2288
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5482
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5395
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3936
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4726
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8163
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.631
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6685
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43137
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36567
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4339
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5701
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9042
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6117
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60875
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3214
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.7816
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0406
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09655
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9437
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1524
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5771
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.134
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51912
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28012
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3675
JA-85-SW39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410424
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7544
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.933
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9422
PMC12180985-BLOODA_ADV-2024-014495-mmc1.pdf-12-IRX3_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.27895
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18803
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06661
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5555
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0735
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5002
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0022
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10591
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6672
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4036
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6287
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3334
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308517
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.2801
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2061
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41669
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20654
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5299
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17951
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2873
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3127
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3725
GSE135350_3_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2572
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8112
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5812
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92974
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1896
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0245
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6545
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51893
CRCGN017_MCF10A.TP53.M_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04739
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38236
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4296
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35243
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5504
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.907
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22525
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53865
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5035
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55904
Cysteine synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.125
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7789
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6549
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0869
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1596
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4163
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64456
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.8938
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0298
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1679
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4805
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7764
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5082
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.698
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2829
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8859
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.51239
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7238
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50295
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0701
PMC11525188-41588_2024_1893_MOESM4_ESM.xlsx-Supplementary_Table_4-Supplementary_Table_4_NSD2_signature_genes_and_GREAT_genes_associated_with_NSD2-dependent_and_NSD2-independent_AR_binding_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94354
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05369
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1623
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.18319
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1917
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6455
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.5788
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44062
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.386
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2583
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0007
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20948
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4134
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60475
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4258
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09055
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4347
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8242
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1955
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6916
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5746
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4891
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1774
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3945
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4698
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.97375
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7108
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.6791
CRCGN014_HEPG2_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03648
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4373
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4991
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38227
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2546
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34373
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2311
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51515
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84735
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1211
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8228
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.2642
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7979
CRCGN015_MCF10A_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18849
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.9023
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4712
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7459
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86097
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8293
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.224
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1497
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35401
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97005
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4456
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3414
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2769
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3376
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5065
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.64516
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4933
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0581
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49735
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7527
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301103
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.977
CRCGN011_HEPG2_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36235
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.515
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9762
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.444
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3069
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6214
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4814
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6265
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30186
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1944
CRCGN015_HEPG2_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18065
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6336
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.31655
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3261
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3349
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2916
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.1925
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.59245
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.586
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0732
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8655
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7271
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31887
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7299
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.582866
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0046
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1945
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2482
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.88
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68454
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5847
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77212
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204744
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18435
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98062
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.79388
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.6363
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366825
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9688
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8648
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1197
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5324
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1979
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.902
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.764
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5678
GSE180185_4_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.81
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6003
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0629
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02096
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7266
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0734
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7558
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6119
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5494
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4737
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01368
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1744
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5668
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0585
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9906
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87805
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7518
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7497
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2472
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.85959
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5778
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4872
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0958
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6116
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.343
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1053
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0742
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8335
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7419
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4114
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5092
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.8546
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14668
GSE130620_1_v_0_kdm4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9238
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8035
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7784
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4312
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75922