association	dataset	threshold value	standardized value
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9865
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9965
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7721
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3405
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6423
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1512
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.839
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7319
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2637
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4884
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2127
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9204
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.27395
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5627
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1046
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3043
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9944
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2736
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5805
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3303
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9813
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0987
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0157
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6229
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3208
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.98064
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.703
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4543
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1003
496100310_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2894
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0663
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.165
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4221
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1227
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.92815
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2775
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4341
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7013
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.8228
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.431
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3133
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0328
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.854
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1514
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8966
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.14555
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0897
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.9549
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.666
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6984
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5453
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.84274
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6913
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0748
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9156
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89876
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3781
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0059
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8579
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6149
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.141
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0417
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3806
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3257
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2847
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7594
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2346
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3091
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6351
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3342
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.28
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.521
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4393
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1869
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.0401
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.817
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0751
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.416
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7156
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1206
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2712
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.43207
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6779
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1283
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5639
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8554
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.359
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0348
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.92
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.4797
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3314
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6133
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5789
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.967
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7794
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9021
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1731
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.6735
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3328
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5162
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5477
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4385
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.407
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9078
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0824
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4245
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7902
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.423
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7752
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.545
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9533
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3924
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1043
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1296
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8071
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5129
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2769
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8351
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0727
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.656
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0109
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7591
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0355
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8885
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.429
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6338
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7369
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7871
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5298
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7923
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6259
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5956
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6811
GSE115542_2_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2515
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3838
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2124
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8153
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8086
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	292.142
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5393
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1505
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6506
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9141
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5508
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0488
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4468
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5187
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4319
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5417
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5663
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.39518
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3036
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.35
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7883
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8886
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9316
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7658
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9777
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1061
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7986
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4502
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7769
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6149
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4156
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7288
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1352
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7902
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2608
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6407
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0597
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2186
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6546
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.572
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1908
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8573
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9376
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8325
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7343
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4132
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4279