association dataset threshold value standardized value MAEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87154 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04169 PTPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64978 SRSF11 Pathway Commons Protein-Protein Interactions 1.0 null TCAP Pathway Commons Protein-Protein Interactions 1.0 null GSE89767_6_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRKD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24307 DHX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98672 GTEX-X62O-0826-SM-46MW8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70083 UFD1-NPL4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.981 hsa-miR-519e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 18787207-TableS2 GeneSigDB Published Gene Signatures 1.0 null hsa-miR-340 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 SQSTM1 Pathway Commons Protein-Protein Interactions 1.0 null RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9676 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7433 GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles 1.0 1.50379 Striatum-like amygdalar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44526 septodiagonal transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10865 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.957498 CAL54 CCLE Cell Line Gene Expression Profiles 1.0 1.98788 GTEX-WYBS-1226-SM-3NM9N GTEx Tissue Sample Gene Expression Profiles 1.0 1.94812 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135030_11_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE102467_1_v_0_pazopanib_human RummaGEO Drug Perturbation Signatures 1.0 null SCLY ChEA Transcription Factor Targets 1.0 null CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.969602 Restrictive cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCFC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75866 ILVBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04153 GSE128730_7_v_6_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8706 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.83111 Roxadustat_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0133684 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 GSE148200_0_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE112860_5_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CJUN-26792858-CHIP-SEQ-BT549-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25703 EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12962 GSE131649_6_v_10_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE128730_4_v_2_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null ELF5 ChEA Transcription Factor Targets 1.0 null IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2853 GSE164505,GSE164506_3_v_1_indisulam_human RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of Dg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33597 Paraphimosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7061 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864342 FBLIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21975 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45155 FMNL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1481 PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null HNRNPLL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26775 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-5096 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 GFM1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.179 Perturb_280_KD_SFMBT1_SRP234978 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.8861 GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14915 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null increased heart weight MPO Gene-Phenotype Associations 1.0 null amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23056 hsa-miR-515-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HSPA12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69252 MRPL30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48926 GSE198794_0_v_3_usp18_human RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21159 hsa-miR-3916 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KIRREL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95846 TP53_01_38 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -1.34 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.289 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61428 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Abemaciclib_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0213361 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62451 TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Skin TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.055 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79684 GSE135030_8_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17271 Extensor digitorum longus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.953 GSE102467_3_v_2_pazopanib_human RummaGEO Drug Perturbation Signatures -1.0 null TMEM170B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83099 TBL1XR1_02_178 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.43296 NCI-H196 COSMIC Cell Line Gene Mutation Profiles 1.0 null URB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.061 hsa-miR-3612 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 SNUC5 CCLE Cell Line Gene Expression Profiles -1.0 -2.23991 karpas707 HPA Cell Line Gene Expression Profiles 1.0 0.940995 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRPF8 Pathway Commons Protein-Protein Interactions 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.879388 Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.34318 NASP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28812 MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.316 abnormal skeletal muscle morphology MPO Gene-Phenotype Associations 1.0 null GSE135030_8_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4722 GTEX-WEY5-0226-SM-3GIKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.30145 GSE194396,GSE194429_1_v_0_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.165 EFO21 CCLE Cell Line Gene CNV Profiles -1.0 -2.30714 GSE180185_4_v_1_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70565 GSE180468_3_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43697 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90754 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.8919 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29891 OTUB2 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2807 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864342 CYP51A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5432 Artesunate_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0163473 regulation of cellular process GO Biological Process Annotations 2015 1.0 null RNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68672 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.786 TBRG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47612 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.968529 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13304 MONOMAC1 CCLE Cell Line Gene CNV Profiles 1.0 1.37681 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null EC-GI-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null PTDSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85252 Cob TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3473 GTEX-WH7G-0426-SM-3NMBJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.9582 GSE215351,GSE215794_4_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3304 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 0.886708 KYO1 DepMap CRISPR Gene Dependency 1.0 4.98838 Fast muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.178 ZNF384_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65662 RFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92001 SEPT2 Pathway Commons Protein-Protein Interactions 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74635 Perturb_6977_OE_ALOX12_SRP321065 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Primary somatosensory area, upper limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41728 GSE235701,GSE261434_2_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40226 SOX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5679 GSE146982_4_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null BCL2L12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30589 H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.801409 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6991 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07295 Medullary reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20863 ETV6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2243 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01624 GSE109565_12_v_11_glyphosate_human RummaGEO Drug Perturbation Signatures 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8064 20035825-TableS4a GeneSigDB Published Gene Signatures 1.0 null ESRRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38978 NCI-H748 COSMIC Cell Line Gene Mutation Profiles 1.0 null Flumatinib (mesylate)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0187045 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26561 GSE135030_8_v_10_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null EVX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94143 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49829 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HMGCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34028 Costamere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.42 NEDD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42472 GTEX-XXEK-0926-SM-4BRWH GTEx Tissue Sample Gene Expression Profiles 1.0 0.878058 USP7 Pathway Commons Protein-Protein Interactions 1.0 null NCIH2452 CCLE Cell Line Gene CNV Profiles -1.0 -1.42843 USF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EOMES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51252 ADAM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80357 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.8747 abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.067362 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26578 preoptic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16933 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19129 cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.255834 UBTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1852 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 0.879283 CDKN1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49067 interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2603 GTEX-WYJK-1026-SM-3NM8W GTEx Tissue Sample Gene Expression Profiles 1.0 0.959755 SIN3A ENCODE Transcription Factor Targets 1.0 null abnormality of cardiac morphology GWASdb SNP-Phenotype Associations 1.0 0.594816 RANGRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41423 Hypertrophic Obstructive Cardiomyopathy DisGeNET Gene-Disease Associations 1.0 null GSE120370_0_v_6_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Muscle Damage DisGeNET Gene-Phenotype Associations 1.0 null GSE146982_7_v_1_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null Mesangial proliferative glomerulonephritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.357 ESR1-20079471-T-47D-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 PGM2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47571 GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31316 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.748185 hsa-miR-513b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFATC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42083 GTEX-WY7C-0526-SM-3NB3D GTEx Tissue Sample Gene Expression Profiles 1.0 2.27413 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null NCIH1781 CCLE Cell Line Gene CNV Profiles -1.0 -1.99569 S100A9 Pathway Commons Protein-Protein Interactions 1.0 null Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 GTEX-P4PP-0326-SM-33HC4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36602 testis HPA Tissue Protein Expression Profiles 1.0 1.3731 POFUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.994 GSE171352_2_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null FLAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56376 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null EID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69086 GSE164874_5_v_0_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null IGDCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52382 HEXIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78658 protein modification by small protein conjugation GO Biological Process Annotations 2023 1.0 null SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01711 E2F4 Pathway Commons Protein-Protein Interactions 1.0 null ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_16478_OE_Klk6_SRP245408 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 DHODH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05932 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865784 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40226 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81902 GTEX-SE5C-0626-SM-2XCDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.78529 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SECISBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04979 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.9738 TRA2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34052 PKP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49678 PMC6344081-elife-40364-supp5.xlsx-PLZF_peaks_H3K27Ac_unchanged-Unnamed_10_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.46447 RNF227 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92939 SAR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37969 INPP4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35425 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.84241 RFX5 ENCODE Transcription Factor Targets 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles 1.0 0.835949 FBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62591 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.962083 Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medial amygdalar nucleus, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47556 cingulate gyrus, frontal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27293 Bloodstream form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.018 RANBP2 Pathway Commons Protein-Protein Interactions 1.0 null ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0564 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06555 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860191 COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.69933 SYK_druginhibition_283_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.17409 Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ischemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09 SYT13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8566 Zinc finger, RING/FYVE/PHD-type InterPro Predicted Protein Domain Annotations 1.0 null GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.938825 ATF3-23680149-GBM1-GSC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SK-MES-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.626 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40885 ILF2_02_152 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.07039 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864342 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TMCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09184 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 ARPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60528 LLGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36294 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.68112 PAX5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE160001,GSE160670_0_v_2_lapatinib_human RummaGEO Drug Perturbation Signatures -1.0 null Familial hypertrophic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.423 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles 1.0 0.8502 primary atrial arrhythmia GWASdb SNP-Phenotype Associations 1.0 0.434952 NFIA Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57147 SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835603 GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles 1.0 1.23944 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.839787 ZCCHC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15294 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53917 GTEX-XGQ4-0526-SM-4AT6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.49633 NODAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71059 A3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures -1.0 null SDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58902 kidney disease GWASdb SNP-Disease Associations 1.0 1.03858 GSE154936_3_v_2_remdesivir_human RummaGEO Drug Perturbation Signatures 1.0 null NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8253 GTF3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99215 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40446 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4582 substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.99622 MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07894 Anterior cingulate area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91435 decreased heart rate MGI Mouse Phenotype Associations 2023 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null HMGN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54632 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40198 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.25234 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 0.884591 PGGHG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36625 GSE128730_4_v_5_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null SMAD2-18955504-HACAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PCNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43415 CDC14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12846 SKLU1 CCLE Cell Line Gene Expression Profiles 1.0 1.49783 GSE174586_0_v_1_slc4a11_mouse RummaGEO Gene Perturbation Signatures -1.0 null CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8113 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.301797 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34542 BV173 CCLE Cell Line Gene CNV Profiles 1.0 2.29958 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50239 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08696 RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU1033 DepMap CRISPR Gene Dependency 1.0 3.88388 cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 ARHGEF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19592 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.826378 SRF-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2604 BCL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11524 outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834968 GTEX-U4B1-0326-SM-3DB8K GTEx Tissue Sample Gene Expression Profiles 1.0 1.54911 Perturb_6027_KD_KHDRBS1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.37821 Myoblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.494 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.5776 PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GSE159678_4_v_2_chloroquine_human RummaGEO Drug Perturbation Signatures 1.0 null PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_CUTOFF_2_5_TOTAL-HAND1_HAND1 Rummagene Transcription Factor Associations 2026 1.0 null BORCS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49422 NCI-H157 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.167 Sarcoma_SARC_TCGA-QQ-A8VF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles 1.0 1.69236 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Chronic Heart Failure DisGeNET Gene-Disease Associations 1.0 null abnormal skeletal muscle fiber size MPO Gene-Phenotype Associations 1.0 null GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.18585 Sacrospinalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.989 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiomyocyte signaling converging on titin WikiPathways Pathways 2024 1.0 null NUGC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.76568 BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Epimastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.255 Perturb_16309_KD_RECQL4_SRP270276 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HES6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3847 HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.02097 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.838846 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928879 pyramidal layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1088 RHOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83925 decreased fasting circulating glucose level MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-2964a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mRNA_TUBA1A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE172458_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null DAPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43076 FUCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06291 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.115 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.846478 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884514 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898875 USF1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAMSTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90632 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null t58-heart_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.80782 ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Intramuscular adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 Gastrocnemius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.348 EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null microtubule cytoskeleton GO Cellular Component Annotations 2023 1.0 null 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.69623 GTEX-Q734-0326-SM-48U15 GTEx Tissue Sample Gene Expression Profiles 1.0 0.984997 RRBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32322 ATPAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18833 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE228619_0_v_1_cdh11_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.24602 DCAF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75728 GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles 1.0 2.58461 TP53-18474530-U2OS-human ChEA Transcription Factor Binding Site Profiles 1.0 null OCIMY5 DepMap CRISPR Gene Dependency 1.0 3.58997 mantle zone of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07195 AHR-22903824-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Phagophore assembly site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.62 MAP1LC3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71337 HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47702 GLOD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03445 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59566 ubiquitin protein ligase activity GO Molecular Function Annotations 2025 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.832264 SELENOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54223 Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65622 SAP18 Pathway Commons Protein-Protein Interactions 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.777 Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.2517 posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1888 GSE184892_6_v_1_trehalose_human RummaGEO Drug Perturbation Signatures 1.0 null PCGF1 Pathway Commons Protein-Protein Interactions 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_35_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null G402 CCLE Cell Line Gene Expression Profiles 1.0 2.25281 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.49884 GSE216273,GSE216292_0_v_1_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.8687 Hyaline body myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.013 mitochondrion-derived vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.538 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 3.95746 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4751 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6088 GSE135352_6_v_3_napabucasin_human RummaGEO Drug Perturbation Signatures -1.0 null heart_6b HPA Tissue Sample Gene Expression Profiles 1.0 1.45175 PNMA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37753 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null MACROH2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47862 Soleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.649 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.086 PTGES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36631 PDIA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4079 GSE196259_2_v_0_gcm1_human RummaGEO Gene Perturbation Signatures 1.0 null IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.3494 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06672 GSE192860_0_v_1_trifluoperazine_human RummaGEO Drug Perturbation Signatures 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53I13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56761 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles 1.0 0.850297 Right atrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.059 ARFGAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1525 GTEX-UJHI-0426-SM-3DB8Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.4991 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased skeletal muscle fiber size MPO Gene-Phenotype Associations 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0153 PSORS1C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.16819 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04212 liminal part of the r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63443 Perturb_259_KD_PBRM1_SRP358304 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE210101,GSE210114_7_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25703 GTF2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04013 UBE2D1 Pathway Commons Protein-Protein Interactions 1.0 null SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33329 FAM72B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71919 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53916 GSE88819_6_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POU2AF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09754 EMSY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7316 TMEM238 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85763 NCIH2171 CCLE Cell Line Gene CNV Profiles -1.0 -1.32459 ANKRD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46259 CRELD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49323 Familial partial lipodystrophy type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.18 HTATSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08915 MRPL47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 ATRAID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28415 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837543 GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MTFMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06997 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1728 FHC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.835 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.542 CEND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14428 KYM1 CCLE Cell Line Gene Expression Profiles 1.0 1.72445 mantle zone of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51569 USP5 Pathway Commons Protein-Protein Interactions 1.0 null SCARB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89102 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3689e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE213153_1_v_0_ulixertinib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC10244377-41467_2023_38797_MOESM7_ESM.xlsx-4d_BioGRID_RBP-BIOGRID_CDC5L_CDC5L Rummagene Transcription Factor Associations 2026 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03815 CBFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01655 PMC10679653-mmc4.xlsx-ISL1_KO_Markers_T_L-Unnamed_0_ISL1 Rummagene Transcription Factor Associations 2026 1.0 null RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4772-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE175787_4_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null DCTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89637 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76607 KDM3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52728 LMSU CCLE Cell Line Gene CNV Profiles 1.0 1.34797 lateral preoptic area, PO1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62368 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESPL1 Pathway Commons Protein-Protein Interactions 1.0 null sublayer 6b of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43105 CRABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06047 USF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9341 SCARF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30169 COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 PEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43654 WM1552C COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE253799_0_v_1_matn3_mouse RummaGEO Gene Perturbation Signatures 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059033 Lung adenocarcinoma_LUAD_TCGA-55-6980-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A172 CCLE Cell Line Gene CNV Profiles -1.0 -1.53358 Perturb_12061_KO_Stat5a_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 muscle phenotype MPO Gene-Phenotype Associations 1.0 null KLF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26999 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4848 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Y-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Microtubule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.900336 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0594 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0509 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7997-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE128730_0_v_5_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QLQ7-0526-SM-2I5G3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38703 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17271 ZDHHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62961 HCC2157 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.40732 MAST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37231 OVKATE COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.2097 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40226 arrhythmia GWASdb SNP-Phenotype Associations 1.0 0.161942 Intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.692 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 0.968983 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.547326 OLIG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32195 hsa-miR-3133 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 POLR2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74357 SNUC4 CCLE Cell Line Gene Expression Profiles -1.0 -2.41319 GTEX-QMRM-0526-SM-2I5GA GTEx Tissue Sample Gene Expression Profiles 1.0 1.0468 CHID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55783 NCIH1435 CCLE Cell Line Gene CNV Profiles 1.0 1.56568 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84277 PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-1626-SM-46MWE GTEx Tissue Sample Gene Expression Profiles 1.0 1.00228 GSE223893_2_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02385 Anterior cingulate area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00464 GSE131377_4_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CUX1 ChEA Transcription Factor Targets 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ENSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95037 suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24434 EWSR1 ChEA Transcription Factor Targets 1.0 null PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null NKX2-5-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ATXN3 Pathway Commons Protein-Protein Interactions 1.0 null BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1981 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.2291 496100407_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01105 PPP1R18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66802 liver_d HPA Tissue Sample Gene Expression Profiles 1.0 1.01037 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null UQCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77524 ACHN CCLE Cell Line Gene Expression Profiles 1.0 3.15279 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUDT17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6917 ENGASE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46454 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CYB561A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4235 SEPTIN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31886 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5469 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40478 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14616 olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08964 intracellular organelle GO Cellular Component Annotations 2015 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960614 GSE169205_3_v_5_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHWD-0426-SM-3LK83 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01636 CYP26A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09472 enlarged heart MPO Gene-Phenotype Associations 1.0 null SMAD3_01_352 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.614 GSE228106_0_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null Myofibrillar myopathy 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.971 Coronary heart disease event reduction (statin therapy interaction) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.630103 RMI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28648 GTEX-WHWD-0326-SM-3LK6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.4327 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE92364_0_v_3_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.882632 GSE193999,GSE194000_1_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0704 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77825 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865835 GSE242083,GSE242098_3_v_5_med1_human RummaGEO Gene Perturbation Signatures -1.0 null protein complex GO Cellular Component Annotations 2015 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 4.28808 Perturb_5570_KO_NFKBIA_SRP149723 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.6036 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4704-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.960114 Muscle TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946673 UGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98111 GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles 1.0 1.05987 Perturb_8833_KO_RING1A_SRP345831 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null r10 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25506 Hyperplasia CTD Gene-Disease Associations 1.0 1.16967 GSE169205_0_v_6_sirt5_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_9834_KO_miR31_SRP354225 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33956 ELP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96832 MIER2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.80476 lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22126 HSD11B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2762 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997148 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.494528 OCT4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79312 regulation of non-canonical NF-kappaB signal transduction GO Biological Process Annotations 2025 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.927639 hsa-miR-20a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles 1.0 1.246 Slow muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.337 PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1 Rummagene Transcription Factor Associations 2026 1.0 null PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_H_sapiens_970_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null CASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09465 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960614 RH18 CCLE Cell Line Gene Expression Profiles 1.0 1.59156 SOX4-29892750-EML-MOUSE-BONEMARROW ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08427 ELK3-25401928-HUVEC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ADGRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47199 MTCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91853 SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 Perturb_12064_KO_Stat5a/Stat5b_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior cingulate area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27106 NFKBID CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 GTEX-WEY5-0426-SM-3GIKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.09968 FGF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61369 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34852 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25844 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-R55G-0526-SM-2TC5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.55512 20502458-TableS6b GeneSigDB Published Gene Signatures 1.0 null H2AC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88283 MK-3903_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0164352 CHEK1_knockdown_142_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.82232 r9 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53258 AR_01_278 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60906 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.44528 hsa-miR-190 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE216273,GSE216292_0_v_8_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE154081_3_v_0_sildenafil_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null NFIX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94179 Perturb_3146_KO_Mrfta/Mrtfb/Myocd_SRP388810 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.54 POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Skeletal muscle myofibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.635 GSE65617_2_v_4_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40354 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.2465 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840727 SMAD2-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null HCC15 DepMap CRISPR Gene Dependency 1.0 2.18112 hsa-miR-1228 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SIX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92357 PSMA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55069 Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null increased quadriceps weight MPO Gene-Phenotype Associations 1.0 null NRIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15024 GTEX-X4EP-0326-SM-3P5Z6 GTEx Tissue Sample Gene Expression Profiles 1.0 2.5974 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77914 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40417 AUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96111 TAL1 ENCODE Transcription Factor Targets 1.0 null Nkx-2.5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.875 USF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148200_3_v_5_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE132369,GSE132371_3_v_0_cccp_human RummaGEO Drug Perturbation Signatures -1.0 null WDR83 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87241 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 0.910661 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838149 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.18808 hsa-miR-411 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE220813_0_v_1_zfp750_mouse RummaGEO Gene Perturbation Signatures -1.0 null PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU3F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45436 HCC1419 COSMIC Cell Line Gene Mutation Profiles 1.0 null Myotonic dystrophy type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.65536 H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RERFLCAD1 CCLE Cell Line Gene Expression Profiles 1.0 1.47181 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05628 GTEX-U8XE-0926-SM-3DB8V GTEx Tissue Sample Gene Expression Profiles 1.0 1.58871 C zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.786 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00177 GTEX-RUSQ-0526-SM-2TF72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83007 GSE155031_6_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null NHP2L1 Pathway Commons Protein-Protein Interactions 1.0 null prostate HPA Tissue Protein Expression Profiles -1.0 -0.748185 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31155 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3588 ubiquitin-protein transferase activity GO Molecular Function Annotations 2023 1.0 null MYOT Pathway Commons Protein-Protein Interactions 1.0 null UBE2Q2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40836 GSE248045,GSE248046_6_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE138863_2_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62451 MCAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54429 ATF3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2458 GTEX-WHPG-0826-SM-3NMBF GTEx Tissue Sample Gene Expression Profiles 1.0 1.32677 TM6SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22415 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4517 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01436 SGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65792 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1507 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SCRIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65989 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lamin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.518 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01992 Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51217 CHCHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20336 GSE193258,GSE193259_9_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23599 PPARD ChEA Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prolonged RR interval MGI Mouse Phenotype Associations 2023 1.0 null GSE233679_14_v_7_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null heart disease GWASdb SNP-Disease Associations 1.0 0.693234 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50554 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.890755 FBXL22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8536 E2F6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32315 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64016 ZNRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82246 MBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96336 EEF2KMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40706 GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null Skeletal muscle TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null H2AK5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22719 TMEM43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28682 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null ABCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95509 GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09953 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 0.910604 AT7519_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0278967 PL4 COSMIC Cell Line Gene Mutation Profiles 1.0 null nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12591 CHD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37094 GTEX-WHSE-0926-SM-3NMBS GTEx Tissue Sample Gene Expression Profiles 1.0 1.41305 POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08389 Perturb_3686_KD_RARRES2_SRP287866 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78612 Tibialis anterior TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.438 USF2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null F-actin capping protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.77 mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22394 GSE160001,GSE160670_1_v_2_lapatinib_human RummaGEO Drug Perturbation Signatures -1.0 null ARHGAP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50784 UBIAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95626 increased skeletal muscle size MPO Gene-Phenotype Associations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07574 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.99738 C2C12 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.545 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.19643 GSE164874_5_v_14_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8323949-pcbi.1009228.s007.xlsx-HNSCC_ALL_exceptLN-X17_ZNF717 Rummagene Transcription Factor Associations 2026 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9978 limb-girdle muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.352 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.6004 RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inferior frontal gyrus, opercular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15173 intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -1.48809 GSE186707_1_v_0_hdac4_mouse RummaGEO Gene Perturbation Signatures -1.0 null WARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03859 mantle zone of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01436 HSC2 DepMap CRISPR Gene Dependency 1.0 2.49281 B3GAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12046 PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3 Rummagene Transcription Factor Associations 2026 1.0 null HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47702 CHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63885 RAB17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93004 EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24505 PMC8323949-pcbi.1009228.s007.xlsx-X17-Unnamed_0_ZNF717 Rummagene Transcription Factor Associations 2026 1.0 null APLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95556 GTEX-NFK9-0926-SM-2HMJU GTEx Tissue Sample Gene Expression Profiles 1.0 0.878947 MPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54159 Central amygdalar nucleus, capsular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0594 ZNF81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD2 ChEA Transcription Factor Targets 1.0 null mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41761 CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF ENCODE Transcription Factor Targets 1.0 null GTEX-WY7C-1126-SM-3NB3A GTEx Tissue Sample Gene Expression Profiles 1.0 1.77374 microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.394323 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25274 RABAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03396 G6PC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33403 UBAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8467 Organellar ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.467 Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45142 UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89114 CCT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16193 GSE135030_3_v_10_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUNAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52221 Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.896953 GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null MFHAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46759 hsa-miR-3614-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null atrial fibrillation GWASdb SNP-Phenotype Associations 1.0 0.434952 NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null Autosomal recessive limb-girdle muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 Liver Failure, Acute CTD Gene-Disease Associations 1.0 1.02447 liver_c HPA Tissue Sample Gene Expression Profiles 1.0 0.878145 ATF3 ENCODE Transcription Factor Targets 1.0 null KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KDM2B-26808549-CHIP-SEQ-DND41-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7176 GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.869239 CAMSAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61598 GSE167474_2_v_3_naa40_human RummaGEO Gene Perturbation Signatures -1.0 null RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3516 EEF1G Hub Proteins Protein-Protein Interactions 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 C6orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67016 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.222083 PRDM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51693 ARRDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69579 GSE174701_1_v_0_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null GSE205163,GSE205164_5_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles 1.0 0.92506 LSS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25209 thyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.748185 hsa-miR-4648 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Fast twitch muscle fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.076 GTEX-XV7Q-0726-SM-4BRV6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51789 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0874 Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased skeletal muscle mass MPO Gene-Phenotype Associations 1.0 null GTEX-SUCS-0326-SM-32PLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.8882 GSE67266_7_v_1_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE184892_7_v_2_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55C-0326-SM-3GAF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24053 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.066 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300 ChEA Transcription Factor Targets 1.0 null Heart valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 BHLHE41 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7263 BHT101 CCLE Cell Line Gene CNV Profiles 1.0 2.53696 microtubule cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.29586 COBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7293 PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA Rummagene Transcription Factor Associations 2026 1.0 null L-363 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960614 EFM19 CCLE Cell Line Gene CNV Profiles -1.0 -2.34082 GTEX-W5X1-0826-SM-3GILN GTEx Tissue Sample Gene Expression Profiles 1.0 1.70636 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Microtubule cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 USP42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16099 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pralsetinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0287675 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null ATXN3L Pathway Commons Protein-Protein Interactions 1.0 null KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null A band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.334 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.73782 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDST8 CCLE Cell Line Gene Expression Profiles 1.0 2.13761 hsa-miR-133b TargetScan Predicted Conserved microRNA Targets 1.0 0.154935 GSE153354_0_v_1_tcf19_human RummaGEO Gene Perturbation Signatures 1.0 null GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ALG10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82563 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.173814 CTCF ENCODE Transcription Factor Targets 1.0 null M band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.39 RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47476 16397240-SuppTable9 GeneSigDB Published Gene Signatures 1.0 null MKNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89495 STK17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86404 TMTC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68082 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01856 HCC1897 CCLE Cell Line Gene Expression Profiles 1.0 1.84773 NB-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39163 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles 1.0 0.848697 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.70061 hsa-miR-3125 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 myosin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.105049 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.883998 MPPE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59246 Mitochondrial small ribosomal subunit COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.357 C1orf159 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58835 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNAJC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57586 RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE223893_4_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null RBM12B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69398 ZNF778 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91033 POU2F2_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null LENG9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37492 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12304 GALT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62708 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.08887 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0625 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.859505 GSE152637_1_v_0_imiquimod_mouse RummaGEO Drug Perturbation Signatures 1.0 null Parasitic protozoa infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.309 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.4564 fh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.635 496100519_HIP_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.72989 GTEX-QEG4-0426-SM-33HC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38621 GTEX-XXEK-2026-SM-4BRVE GTEx Tissue Sample Gene Expression Profiles 1.0 1.09135 TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null HMGB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59602 ISTMES2 CCLE Cell Line Gene CNV Profiles -1.0 -1.58193 cardiac muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.573616 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4692 TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 NIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01513 Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196339 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null GSE151612_4_v_10_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null PMC10209342-mmc9.xlsx-UBE2D3_interactors-UBE2D3_interactors_used_for_Venn_Diagrams_from_MINT_STRING_UniProt_IntAct_BioGRID_SPEN Rummagene Transcription Factor Associations 2026 1.0 null APBB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27284 intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28202 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2435 hsa-miR-4643 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 SNU761 CCLE Cell Line Gene CNV Profiles -1.0 -1.37013 HEY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7045 Heart primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.502 r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.394 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06555 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50239 Perturb_3145_KO_Mrfta/Mrtfb_SRP388810 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.37248 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.42144 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TOP1MT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7055 H2AC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18213 i band COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.201335 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null TCF12_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Urophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.71 GK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71186 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7928 GSE175787_5_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null 29-13 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.655 H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.975712 microtubule cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE244710_3_v_2_srsf1_human RummaGEO Gene Perturbation Signatures -1.0 null liminal part of the r8 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07195 GSE130401_4_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null KMRC3 CCLE Cell Line Gene Expression Profiles 1.0 1.91345 Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.63221 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3704 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles 1.0 0.85475 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.98895 ARRDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.16112 BHLHE40 ENCODE Transcription Factor Targets 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.034841 Scapuloperoneal myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null Dilated cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.679 SNU423 CCLE Cell Line Gene Expression Profiles 1.0 2.00627 SETDB1-19884257-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.843 PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GSE152937_12_v_7_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_MYBL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null WSU-NHL COSMIC Cell Line Gene Mutation Profiles 1.0 null ZDHHC23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32207 Medullary reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49906 polymeric cytoskeletal fiber GO Cellular Component Annotations 2023 1.0 null ANXA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54522 LRRC42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2123 Myofilament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.566 r3 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09286 Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null a band COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.11378 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4722 XRCC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60602 ZNF233 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91112 SMIM30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71257 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER ChEA Transcription Factor Targets 2022 1.0 null carcass TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.38552 fast muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.627889 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Subparafascicular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.524 llcmk2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.543 OCUBM DepMap CRISPR Gene Dependency 1.0 4.09546 FOSL2 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TIMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45018 GSE213996_1_v_0_fhl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null SAPCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47001 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null MEF2A-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE164874_5_v_12_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null TET2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54241 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null GTEX-V955-0726-SM-3GAFG GTEx Tissue Sample Gene Expression Profiles 1.0 0.982983 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4913 superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46605 Fatigue DisGeNET Gene-Phenotype Associations 1.0 null GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles 1.0 1.05519 GSE190316,GSE190324_6_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164874_5_v_9_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041227 CBFA2T3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58171 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40226 GSE130081,GSE130082_0_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ELF5-23300383-T47D-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56081 protein ubiquitination GO Biological Process Annotations 2023 1.0 null Tucidinostat_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.018206 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.748185 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59327 GSE237040_6_v_1_notch3_mouse RummaGEO Gene Perturbation Signatures -1.0 null DPEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54616 TCF3 ENCODE Transcription Factor Targets 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853655 496100619_HIP_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.25027 ZFP64 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50001 GTEX-RWS6-0326-SM-2XCAP GTEx Tissue Sample Gene Expression Profiles 1.0 1.39237 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7972 Muscle fibre TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.85 Medroxyprogesterone acetate_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0215418 GSE223893_11_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null LOVO COSMIC Cell Line Gene Mutation Profiles 1.0 null AKIRIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46594 GSE115763_3_v_1_klf6_human RummaGEO Gene Perturbation Signatures 1.0 null SARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58551 Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2603 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44551 hsa-miR-4298 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ITPRIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8571 mRNA_NR0B1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Twitch muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.279 496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.5629 ATF3-23680149-GBM1-GSC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null vascular tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134994 Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.849988 Adrenocortical carcinoma_ACC_TCGA-OR-A5JC-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE143847_2_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures 1.0 null medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.831162 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.30354 Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 UCKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16391 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152432_1_v_4_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.846048 STX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38742 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05615 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9374760__F3 PFOCR Pathway Figure Associations 2024 1.0 null Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.6402 TTF2 ChEA Transcription Factor Targets 1.0 null IST-SL2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.639 Gracilis muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.922 JHOC5 CCLE Cell Line Gene Expression Profiles 1.0 1.3632 SRSF1 Pathway Commons Protein-Protein Interactions 1.0 null CCK81 DepMap CRISPR Gene Dependency 1.0 2.41411 RMGI CCLE Cell Line Gene Expression Profiles 1.0 1.52265 GSE184892_7_v_3_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48708 LEPROTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99473 H2AFZ ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.537 Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 NZOV9 DepMap CRISPR Gene Dependency 1.0 2.46551 HDDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84623 myosin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.647433 familial atrial fibrillation GWASdb SNP-Disease Associations 1.0 0.509115 TRPM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62733 liminal part of the r9 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.524 Mitral valve insufficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.086 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899263 SMAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9325 PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.27782 Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64724 Acute Myeloid Leukemia_LAML_TCGA-AB-2860-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.951445 hsa-miR-4420 TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE120612_6_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03529 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M7-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PML body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.947 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06444 Sarcomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.183 GPR161 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77095 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.923843 Myofibrillar myopathy 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.098 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.63543 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.899124 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SRF-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -1.38966 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.342 EI24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66064 PINLYP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70784 Lung adenocarcinoma_LUAD_TCGA-44-2662-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDC5L Pathway Commons Protein-Protein Interactions 1.0 null macromolecular complex GO Cellular Component Annotations 2015 1.0 null GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.988411 intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53664 Almonertinib (mesylate)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0247734 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38322 GSE233679_5_v_13_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal muscle morphology MPO Gene-Phenotype Associations 1.0 null HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15222 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M1-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE110268_2_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null 19658189-TableS5 GeneSigDB Published Gene Signatures 1.0 null THOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11508 MDAMB436 DepMap CRISPR Gene Dependency 1.0 4.15343 GTEX-QEL4-0926-SM-3GAD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.959732 fusiform gyrus, right, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.841428 EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMRTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33114 TFCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10801 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.899477 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 PACS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48774 NDUFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58059 FAM236B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47945 SLC25A39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15243 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916906 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.361 POLR2A ENCODE Transcription Factor Targets 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.034932 NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null TRIM23 Pathway Commons Protein-Protein Interactions 1.0 null MORCPR DepMap CRISPR Gene Dependency 1.0 3.41136 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.97639 YOD1 Pathway Commons Protein-Protein Interactions 1.0 null Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1295 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 0.829976 Perturb_15293_OE_Fos_SRP304877 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.4437 GSE216043_11_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE145215_0_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures -1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null skeletal system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82851 GTEX-OHPL-0326-SM-33HC8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29034 Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiovascular system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 bloodstream form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.998037 DDX31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36069 TNFRSF10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96283 PMC10710060-pnas.2305135120.sapp.pdf-8-SRF_SRF Rummagene Transcription Factor Associations 2026 1.0 null Myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.41 r10 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63443 H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PFN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05981 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.193 abnormal muscle fiber morphology MPO Gene-Phenotype Associations 1.0 null Trypanosomoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.471 RUNX1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.224558 MRPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32265 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE175787_8_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null SAFB Pathway Commons Protein-Protein Interactions 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28249 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.873204 intracellular part GO Cellular Component Annotations 2015 1.0 null GSE146982_3_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles 1.0 1.16418 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1049 cell part GO Cellular Component Annotations 2015 1.0 null abnormal heart weight MPO Gene-Phenotype Associations 1.0 null cardiac muscle TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_5899_KD_CHAF1A_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.38086 TMEM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64483 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90754 Dapagliflozin ((2S)-1,2-propanediol, hydrate)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.014537 GTEX-OHPK-0326-SM-2HMJO GTEx Tissue Sample Gene Expression Profiles 1.0 1.08239 NRROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64087 MC1R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19267 terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5154 hand TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.896045 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 0.828092 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null skeletal muscle TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null 19658189-TableS9a GeneSigDB Published Gene Signatures 1.0 null JJN-3 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 USP4 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null TMEM158 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01151 GTEX-RU72-0326-SM-2TF5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.58726 liver GTEx Tissue Gene Expression Profiles 1.0 1.01887 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.33579 heart_6a HPA Tissue Sample Gene Expression Profiles 1.0 1.39966 GSE130401_1_v_0_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60684 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15222 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28468 Naproxen_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0194846 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.99998 CLDND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9804 Severe acute respiratory syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 Hepatic cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.49 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36214 PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR Rummagene Transcription Factor Associations 2026 1.0 null FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2353 GTEX-P78B-0426-SM-2I5F5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57842 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 seminal vesicle HPA Tissue Protein Expression Profiles -1.0 -0.748185 RBM42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04213 hsa-miR-106b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 intermediate stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12794 H2BC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61778 lateral habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868386 first (dorsal) preoptic domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2892 Replication inhibiting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.617 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.880123 GTEX-R53T-0926-SM-3GADH GTEx Tissue Sample Gene Expression Profiles 1.0 1.56332 LSM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12476 RAB35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.756 TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75011 ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32551 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null TATDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.065 CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6994 H3K79me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Left atrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.034 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04144 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TP53-16413492-HCT116-human ChEA Transcription Factor Binding Site Profiles 1.0 null POU2F2 ENCODE Transcription Factor Targets 1.0 null BFTC909 CCLE Cell Line Gene CNV Profiles 1.0 1.83761 kinetoplastid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.59226 MTRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48474 NLGN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65895 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860584 ENTPD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72628 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hexylresorcinol_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0127847 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148 GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null SYTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16502 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJMC-0526-SM-3GAE3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34178 496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.46038 titin-telethonin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.821 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.18859 GSE152432_9_v_4_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FBH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97218 Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3009 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null 18318837-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE216273,GSE216292_0_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null OVTOKO CCLE Cell Line Gene Expression Profiles 1.0 1.39175 GSE135030_8_v_1_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null HOXB7-26014856-BT474-HUMAN ChEA Transcription Factor Targets 2022 1.0 null kinetoplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.554732 Left ventricular noncompaction DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.352 CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05659 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UACC-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE216043_7_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Fat-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 -0.134192 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.39598 Kidney - Cortex GTEx Tissue Gene Expression Profiles 2023 1.0 3.26643 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46146 TCF12_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE226249_2_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15024 GSE193258,GSE193259_5_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null contractile fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.713682 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles 1.0 0.839678 commissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23898 GSE221742,GSE221743_1_v_2_sipa1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UPK5-0226-SM-3GAEV GTEx Tissue Sample Gene Expression Profiles 1.0 2.82343 TMEM132A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03078 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-142-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.44469 PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4 Rummagene Transcription Factor Associations 2026 1.0 null cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.96744 PMC5578490-pgen.1006879.s020.xlsx-ETV1_ChiP_pks_tags_txt-Gene_Name_ETV1 Rummagene Transcription Factor Associations 2026 1.0 null medial amygdala, anterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34612 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06543 hsa-miR-3689f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SRSF10 Pathway Commons Protein-Protein Interactions 1.0 null anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66519 Arid5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.1305 SLC46A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58285 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3776 TMEM168 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.966 GSE128730_7_v_5_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null PGR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65799 GSE213988_0_v_1_rrm2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PLZ5-0626-SM-2I5F8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.33781 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A Rummagene Transcription Factor Associations 2026 1.0 null GSE161055,GSE161056_1_v_0_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOXP2 ChEA Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.17035 PHGDH Pathway Commons Protein-Protein Interactions 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1948 GSE184892_6_v_5_trehalose_human RummaGEO Drug Perturbation Signatures 1.0 null nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.36089 GSE148200_0_v_5_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8 Rummagene Transcription Factor Associations 2026 1.0 null Tolmetin_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0198358 Recurrent major depressive disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 GTEX-WQUQ-1326-SM-3MJFF GTEx Tissue Sample Gene Expression Profiles 1.0 1.05184 Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLEC14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26651 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE109565_12_v_4_glyphosate_human RummaGEO Drug Perturbation Signatures 1.0 null GSE135030_3_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7106 GTEX-V1D1-0626-SM-4JBHN GTEx Tissue Sample Gene Expression Profiles 1.0 1.24202 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAPRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67408 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946473 GSE160083,GSE160084_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ACSM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34649 Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDC80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18948 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.907683 USF2 ENCODE Transcription Factor Targets 1.0 null Parasitic infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283 Colon - Sigmoid GTEx Tissue Gene Expression Profiles 2023 1.0 1.96848 GSE193999,GSE194000_3_v_2_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE131649_2_v_3_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1846 superior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61412 UBE2I Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5572_KO_NFKBIA_SRP149723 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.347 Lung squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.54 heart muscle HPA Tissue Protein Expression Profiles 1.0 2.54719 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.047 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.34509 GSE224969,GSE224971_3_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_13571_KD_Islr_SRP160431 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58032 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.60952 SKNMC CCLE Cell Line Gene CNV Profiles 1.0 1.50065 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00419 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996415 MPST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16066 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1245 TCIRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60988 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928879 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hypocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071083 GSE146687_2_v_1_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null EPHX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14487 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180468_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null cytoskeletal part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 CHD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69641 TAL1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ARNT-22903824-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF619 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05471 SW620 DepMap CRISPR Gene Dependency 1.0 2.43705 NOMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41362 GSE216273,GSE216292_0_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.065465 H3K4me1_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WI4N-0726-SM-3TW93 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26401 abnormal quadriceps weight MPO Gene-Phenotype Associations 1.0 null Sarcoma_SARC_TCGA-DX-A3U8-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles 1.0 1.17388 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74446 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59042 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5857 cell part LOCATE Curated Protein Localization Annotations 1.0 null ARHGEF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48697 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.393 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null LCAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28264 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.157397 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980622 GSE256181_1_v_3_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null SFPQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89495 I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04894 NCI-H1299 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 TMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3159 HS578T CCLE Cell Line Gene CNV Profiles 1.0 1.38754 GGT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13938 GSE135030_3_v_0_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.294 MYOD1_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRKCI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79979 GSE189653,GSE203344_4_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null RH28 DepMap CRISPR Gene Dependency 1.0 2.37448 Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.95035 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.43523 TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TENT4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07044 UCHL5 Pathway Commons Protein-Protein Interactions 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7715 ATXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30338 Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39696 CLPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58101 GSE135352_6_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77669 Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24025 PPP6R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50781 FLT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12507 ELAVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97737 muscle GTEx Tissue Gene Expression Profiles 1.0 1.09708 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59327 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72304 Brain Lower Grade Glioma_LGG_TCGA-IK-8125-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null seedling TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06962 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49227 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles 1.0 0.893108 GSE135030_11_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Thigh TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.314 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09395 Calpain complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.595 GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69259 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00993 ZNF235 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43123 hsa-miR-1825 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 TBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43888 IAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41639 PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1 Rummagene Transcription Factor Associations 2026 1.0 null GSE162892_4_v_5_isox_human RummaGEO Drug Perturbation Signatures -1.0 null lateral posterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20856 dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51217 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 0.836565 ZNF384 ENCODE Transcription Factor Targets 1.0 null MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF799 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87542 binding GO Molecular Function Annotations 2015 1.0 null DZIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.96722 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62451 SNU626 CCLE Cell Line Gene CNV Profiles -1.0 -1.37116 MTHFS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15163 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.380627 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null KMRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.81031 GATA4-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null THOC6 Pathway Commons Protein-Protein Interactions 1.0 null SERINC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36153 hsa-miR-3692 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69747 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0426-SM-2XCF8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869141 Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 RELA ChEA Transcription Factor Targets 1.0 null ZFTRAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89925 heart TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null C5orf24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33459 CWF19L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06342 NPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87887 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.563 cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.849429 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.3427 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 0.888814 Skeletal muscle cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 VENTX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6289 Eye-plasma cell Tabula Sapiens Gene-Cell Associations 1.0 -0.133667 PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null Diaphragm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.142 GTEX-WFG7-0726-SM-3GIKO GTEx Tissue Sample Gene Expression Profiles 1.0 2.05272 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 Perturb_16092_KD_RRM2_SRP398748 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.98865 SERINC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01383 SLC9A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05319 ATR_knockdown_140_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.60323 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-0626-SM-46MVQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.0825 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null SYK_druginhibition_284_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.12825 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64545 L-1236 COSMIC Cell Line Gene Mutation Profiles 1.0 null Anterior olfactory nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.90217 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884514 GTEX-U3ZN-1426-SM-3DB87 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47732 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41731 GSE242083,GSE242098_3_v_1_med1_human RummaGEO Gene Perturbation Signatures 1.0 null RUNX1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-128 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 NPIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67303 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles 1.0 1.28593 GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null KCNK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5931 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 2.10619 TTF2-22483619-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null OSRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.69223 GSE145171_0_v_1_prox1_human RummaGEO Gene Perturbation Signatures 1.0 null ITPRID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15805 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.95652 GSE112358,GSE112359_0_v_1_med23_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884514 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5786 Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.174 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8642 CKM complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.023 mantle zone of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63443 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9651_KO_TREX1_SRP355094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.56604 ONECUT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76787 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 0.922849 PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_14_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null GSE135030_3_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null COL9A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07272 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9607 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null MAPK1_knockdown_112_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.68498 KLK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77323 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05918 Perturb_276_KD_USP13_SRP343502 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.22037 FOXN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89058 H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR1H3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.65388 EZH2 ENCODE Transcription Factor Targets 1.0 null GSE226114,GSE226116_1_v_0_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16019 EDEM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36973 GSE224311_3_v_1_chaetocin_human RummaGEO Drug Perturbation Signatures 1.0 null Autosomal recessive limb-girdle muscular dystrophy type 2J DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09794 forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.58242 PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_13_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null ARVCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97977 Myofibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.187 GTEX-POMQ-0326-SM-2I5FO GTEx Tissue Sample Gene Expression Profiles 1.0 1.25825 GTEX-P4PQ-0326-SM-2HMJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2516 Influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 RPMI-7951 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-VUSG-0726-SM-3GIK1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53902 TMED7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98354 intermediate stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23044 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835658 GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null MAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62474 Tofacitinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0190909 PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC Rummagene Transcription Factor Associations 2026 1.0 null r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39392 r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08436 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02951 HACD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83425 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.913507 TMEM59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09076 DEXI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21949 Liver hepatocellular carcinoma_LIHC_TCGA-O8-A75V-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-568 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.862514 H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE135030_8_v_9_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null STAM Pathway Commons Protein-Protein Interactions 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.90524 Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37931 intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 intermediate stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18401 Superior colliculus, motor related, intermediate gray layer, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24709 LM3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.732 FBLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79566 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10596 ES2 CCLE Cell Line Gene Expression Profiles 1.0 2.53033 TCF12 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRK-0826-SM-2HMK7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28926 TE5 DepMap CRISPR Gene Dependency 1.0 2.24469 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1174 BLOC1S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68749 GSE164874_5_v_10_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE179880_1_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 DCAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58576 ENTPD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22295 GSE242083,GSE242098_3_v_4_med1_human RummaGEO Gene Perturbation Signatures 1.0 null POMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39897 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.828745 Superior colliculus, motor related, intermediate gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17735 ATRIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58331 myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.815514 CANT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66341 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039967 Katanin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.699 GSE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02416 PABPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93199 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4643 Lung adenocarcinoma_LUAD_TCGA-69-7974-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158743_1_v_2_nfkbia_human RummaGEO Gene Perturbation Signatures 1.0 null skeletal muscle hypertrophy MPO Gene-Phenotype Associations 1.0 null GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31016 Tunica Media dbGAP Gene-Trait Associations 1.0 0.073793 GSE216043_11_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XV7Q-0826-SM-4BRV7 GTEx Tissue Sample Gene Expression Profiles 1.0 4.68068 inferior rostral gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.960818 MIEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6612 plant vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.833642 BHT-101 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 GSE218378_1_v_0_pbx1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_4708_KD_Dnmt3b_SRP069225 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 15.4275 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46869 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles 1.0 0.871809 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 GSE193588_3_v_2_pax3_mouse RummaGEO Gene Perturbation Signatures -1.0 null TNFRSF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14957 USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null Striated muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.407 Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7 Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11442 SF3A1 Pathway Commons Protein-Protein Interactions 1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null sclc21h HPA Cell Line Gene Expression Profiles 1.0 0.889069 AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-3673 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865784 NCIH1963 CCLE Cell Line Gene Expression Profiles -1.0 -2.22584 IRX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88158 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957682 RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null cytoskeletal part GO Cellular Component Annotations 2015 1.0 null GSE152937_6_v_5_slc16a13_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE199081_0_v_1_insr_mouse RummaGEO Gene Perturbation Signatures 1.0 null HOOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67357 Respiratory chain complex IV COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.236 TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9329 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83698 mRNA_ID1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 66.164 Myofibrillar myopathy 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0111 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null CFP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69619 ETC-206_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0277528 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inferior frontal gyrus, orbital part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08585 Zinc finger, RING-type InterPro Predicted Protein Domain Annotations 1.0 null GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null Topotecan (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0194274 Perturb_5031_KO_4930500J02Rik_SRP072189 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.35211 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0605 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-0326-SM-4GIEE GTEx Tissue Sample Gene Expression Profiles 1.0 1.28992 mRNA editing complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.658 MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -1.49428 PYGM Pathway Commons Protein-Protein Interactions 1.0 null SDHAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57387 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3243 Phospholamban complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.073 r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07318 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures -1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3498 GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null abnormal quadriceps morphology MPO Gene-Phenotype Associations 1.0 null PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null GSE132369,GSE132371_1_v_0_cccp_human RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.981495 skeletal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.870639 KYSE270 DepMap CRISPR Gene Dependency 1.0 5.93443 PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4 Rummagene Transcription Factor Associations 2026 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840021 not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46514 PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR Rummagene Transcription Factor Associations 2026 1.0 null TIA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42744 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5180-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.926801 Perturb_17760_KO_Lin9_SRP221087 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.50533 SJSA1 CCLE Cell Line Gene Expression Profiles -1.0 -1.91439 inclusion body myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2382 skeletal muscle hypertrophy MGI Mouse Phenotype Associations 2023 1.0 null DST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42859 TUSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53095 DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30613 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plant embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06962 Trypanosomoid form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.882 PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D4_vs_D9-Unnamed_2_CENPX Rummagene Transcription Factor Associations 2026 1.0 null USF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12797 hsa-miR-4695-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 preopto-hypothalamic band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09775 ZNF131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10552 SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 1.56735 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YPEL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89388 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC11015551-12915_2024_1879_MOESM8_ESM.xlsx-depmap_predictability_data_REST-feature_REST Rummagene Transcription Factor Associations 2026 1.0 null Facioscapulohumeral muscular dystrophy 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.053 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7929 PDE6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48694 CACYBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00997 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-SOX14-sequence_name_SOX14 Rummagene Transcription Factor Associations 2026 1.0 null KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-R45C-0926-SM-3GAD4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98644 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.03522 PEX10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75753 TNFAIP8L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77234 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.834736 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05517 POLR2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28638 Lung squamous cell carcinoma_LUSC_TCGA-85-8048-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypertrophic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.808 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TTF2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SOX11_01_213 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.59132 vertebrate muscular system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null bed nucleus of the stria terminalis, mediocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3357 HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.91098 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47165 Supramolecular fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887338 UPCISCC200 DepMap CRISPR Gene Dependency 1.0 3.92358 CNTRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91419 NECAB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5742 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 AGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.046 ubiquitin-like protein ligase activity GO Molecular Function Annotations 2025 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.925346 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12329 POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain - Substantia nigra GTEx Tissue Gene Expression Profiles 2023 1.0 5.5428 YDJC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2559 GAPDHS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46245 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851758 SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 0.870178 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3684 lateral part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33597 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049642 GSE92434_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormal cardiovascular system morphology MPO Gene-Phenotype Associations 1.0 null LKAAEAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52222 liver HPA Tissue Gene Expression Profiles 1.0 1.20627 EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA4 ChEA Transcription Factor Targets 1.0 null spleen HPA Tissue Protein Expression Profiles -1.0 -0.748185 GSE165678_0_v_5_stat5a_human RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12162 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.987293 GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.45375 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6628 GSE147240_3_v_4_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928879 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 Slow twitch muscle fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018 CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8751 MYOG ENCODE Transcription Factor Targets 1.0 null TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6113 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64583 SMCHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 LRP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55914 GSE252857_2_v_3_klf15_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE128730_0_v_1_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864342 intermediate stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06359 Rimonabant_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0186057 NCIH660 CCLE Cell Line Gene CNV Profiles 1.0 1.87496 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CY-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138789_0_v_1_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.158 H3C10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01377 Longissimus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.027 RAB9A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69167 CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.32855 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1732 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null myotube TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.298165 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1255 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supraventricular arrhythmia GWASdb SNP-Phenotype Associations 1.0 0.434952 JUN JASPAR Predicted Transcription Factor Targets 1.0 null upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80217 ZNF274 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18775 RORC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21168 polymeric cytoskeletal fiber GO Cellular Component Annotations 2025 1.0 null GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-371b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Perturb_6965_KO_MFng_SRP057171 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.76904 ITM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1914 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868659 MYOD1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE216757_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31589 CDK2_knockdown_146_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.41444 cellular_component LOCATE Curated Protein Localization Annotations 1.0 null dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96446 SRSF7 Pathway Commons Protein-Protein Interactions 1.0 null USP28 Pathway Commons Protein-Protein Interactions 1.0 null SLC35E4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77809 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.071016 RCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.56882 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6773 Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18868 GSE221539_1_v_3_lrrc10_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles 1.0 1.00199 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4478 Perturb_8649_KO_TBX5_SRP287180 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.2074 TMEM248 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23288 pretectum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01109 Geep TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.424 PNMA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95078 GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles 1.0 1.22112 KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-17 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 SGSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88706 GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles 1.0 0.895503 GSE261177_0_v_1_tnfrsf12a_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles 1.0 0.925552 GSE164874_5_v_7_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null MEF2A ChEA Transcription Factor Targets 1.0 null Congestive Heart Failure DisGeNET Gene-Disease Associations 1.0 null MOLP8 CCLE Cell Line Gene Expression Profiles 1.0 1.45576 SV2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83334 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null GNG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14554 SNU-C1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 0.896457 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9797 tachycardia GWASdb SNP-Phenotype Associations 1.0 0.434952 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.825151 r9 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09286 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912304 Perturb_11667_KD_PTBP1_SRP113334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.51077 Primary somatosensory area, unassigned, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15055 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 0.858228 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.9119 PLA2G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94368 GSE128730_4_v_6_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null BHMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9015 PBX3 ENCODE Transcription Factor Targets 1.0 null KLF5-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE199204,GSE211619_4_v_3_glutamine_human RummaGEO Drug Perturbation Signatures 1.0 null r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14587 intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55579 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.92162 GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null muscular system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RNF114 Pathway Commons Protein-Protein Interactions 1.0 null GSE242367_1_v_0_dpp9_human RummaGEO Gene Perturbation Signatures 1.0 null PMC6300607-41467_2018_7620_MOESM9_ESM.xlsx-common_BRD4-S_KO_MLL-AF9_loci-Unnamed_12_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null BEN CCLE Cell Line Gene CNV Profiles -1.0 -1.47937 IKZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23779 primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21763 GSE188458_2_v_1_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures 1.0 null PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RNOR-0826-SM-2TF5C GTEx Tissue Sample Gene Expression Profiles 1.0 1.17168 GTEX-O5YV-0326-SM-2I5H2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45553 hsa-miR-4712-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles 1.0 0.886309 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 0.904769 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3845 MOLM13 CCLE Cell Line Gene CNV Profiles 1.0 1.68508 Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4729 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02838 m band COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.21946 GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0986 MYOG_myocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE167324_1_v_0_eif4e_mouse RummaGEO Gene Perturbation Signatures -1.0 null TOP3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6302 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6236 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR Rummagene Transcription Factor Associations 2026 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null PCGF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90308 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.873978 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.055 GSE134896_0_v_3_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null COMMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52471 SNU840 DepMap CRISPR Gene Dependency 1.0 2.46227 ACOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26849 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE178267_2_v_4_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null Primary somatosensory area, mouth, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18868 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 0.924537 hsa-miR-4682 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 protein K48-linked ubiquitination GO Biological Process Annotations 2025 1.0 null UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.88354 ZNF543 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43003 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03396 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null PHLDA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21569 ZNF611 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27981 TMEM185B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48022 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840742 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9907 Ross River fever DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 Intranuclear rod COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.521 Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0594 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NR3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65213 TCEA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4031 NMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95767 Hypoglossal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10565 Perturb_5005_OE_Mnx1_ERP140947 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.7846 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5 oral mucosa HPA Tissue Protein Expression Profiles -1.0 -0.748185 medial geniculate nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1666 contractile fiber part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.770451 Extensor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.455 E2F6 ENCODE Transcription Factor Targets 1.0 null tunica media GAD Gene-Disease Associations 1.0 null temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00858 signal transduction GO Biological Process Annotations 2015 1.0 null GSE131649_6_v_3_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.490619 vagina HPA Tissue Protein Expression Profiles -1.0 -0.748185 PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61504 decreased susceptibility to Coronaviridae infection MGI Mouse Phenotype Associations 2023 1.0 null GTEX-PWOO-0526-SM-2S1Q3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50707 IRX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34185 USP13 Pathway Commons Protein-Protein Interactions 1.0 null Skeletal muscle satellite cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 heart conduction disease GWASdb SNP-Disease Associations 1.0 0.271858 Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.29657 UBE3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27857 hsa-miR-3129-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 SCCPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62509 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.08312 SK-ES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C Rummagene Transcription Factor Associations 2026 1.0 null Supramolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 HDAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52744 g7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.159 PMC11833364-tcr-14-01-340-supplementary.pdf-59-ZSCAN18_ZSCAN18 Rummagene Transcription Factor Associations 2026 1.0 null GSE207514,GSE207515_1_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null NEB Pathway Commons Protein-Protein Interactions 1.0 null increased quadriceps weight MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-519d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 CCND2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4374 AKR1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28876 organelle LOCATE Curated Protein Localization Annotations 1.0 null Nucleus ambiguus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12334 ATP5IF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91593 Nucleus of Darkschewitsch Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12334 mantle zone of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10789 EFM192A CCLE Cell Line Gene CNV Profiles -1.0 -3.21037 RIC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28674 RELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32824 GTEX-O5YW-0326-SM-2I5EI GTEx Tissue Sample Gene Expression Profiles 1.0 1.06478 GTEX-XBED-0526-SM-47JY3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27697 RD CCLE Cell Line Gene Expression Profiles 1.0 1.43354 GSE155031_6_v_3_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40226 GSE156454_0_v_1_tamoxifen_human RummaGEO Drug Perturbation Signatures 1.0 null NDUFS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37688 medial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1372 GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles 1.0 0.979787 UHRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23322 abnormal hypaxial muscle morphology MPO Gene-Phenotype Associations 1.0 null intermediate stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2603 TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.084 TEFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34775 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908548 GSE226091,GSE226092_0_v_4_sall1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSS CCLE Cell Line Gene Expression Profiles -1.0 -1.98743 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null prolonged RR interval IMPC Knockout Mouse Phenotypes 1.0 null GSE213228_4_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE146982_7_v_1_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.7748 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCDC28B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02859 hsa-miR-329 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Harderian gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.837 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22255 JHUEM7 DepMap CRISPR Gene Dependency 1.0 2.57182 POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5307 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles 1.0 1.09864 RAB1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60581 hsa-miR-3173-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 muscle TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE233679_5_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null USP8 Pathway Commons Protein-Protein Interactions 1.0 null trypanosomoid form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.527139 ATXN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94863 organelle part GO Cellular Component Annotations 2015 1.0 null FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7168 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02777 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21137 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null GSE193258,GSE193259_2_v_4_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20219 SMAD3 ChEA Transcription Factor Targets 1.0 null Pitavastatin (Calcium)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0220459 PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 RPL21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73186 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08706 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Medial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16945 ENTREP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67309 FOXO3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10733 PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_6503_KD_PIEZO1_SRP140640 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.571 SCAMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01865 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19255 Perturb_5026_KO_4930500J02Rik_SRP072189 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.53923 YKT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61958 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63744 BAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16783 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91141 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE216273,GSE216292_14_v_6_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QDVN-0326-SM-2I3FS GTEx Tissue Sample Gene Expression Profiles 1.0 1.46306 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myofibrillar myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.5 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.04803 GTEX-WFG8-0726-SM-3GILP GTEx Tissue Sample Gene Expression Profiles 1.0 2.00334 NCI-H2087 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.765 TT COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE152432_3_v_2_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null POLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13471 HCC2279 CCLE Cell Line Gene CNV Profiles -1.0 -2.29071 GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null transition metal ion binding GO Molecular Function Annotations 2015 1.0 null POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.363 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMAD3-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-0826-SM-4B654 GTEx Tissue Sample Gene Expression Profiles 1.0 0.984736 GSE92364_0_v_4_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null RPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19015 Thigh muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.402 TCF3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.48132 KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 GSE76425_0_v_7_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null GNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21415 CCAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66246 20081105-ST-1 GeneSigDB Published Gene Signatures 1.0 null SK-N-FI COSMIC Cell Line Gene Mutation Profiles 1.0 null Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21276 disease GWASdb SNP-Disease Associations 1.0 0.035173 Penfluridol_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0280286 Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 ABHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5093 ubiquitin protein ligase activity GO Molecular Function Annotations 2023 1.0 null UBE2J1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24784 APPBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13722 TMSB4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88702 TLX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76489 PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.79531 regulation of biological process GO Biological Process Annotations 2015 1.0 null PLEKHF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87806 Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.023 Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arntl JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.3218 Zinc finger, RING-type, conserved site InterPro Predicted Protein Domain Annotations 1.0 null Mitochondrial pyruvate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 EHEB COSMIC Cell Line Gene Mutation Profiles 1.0 null SLC6A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62969 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22151 MTIF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91069 SERF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37184 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.992835 CRTC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17029 Viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.102 NCI-H1876 COSMIC Cell Line Gene Mutation Profiles 1.0 null shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063654 USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-544 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135030_3_v_5_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12797 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12832 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.16935 SETDB1 ChEA Transcription Factor Targets 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06848 GSE149359_2_v_0_asap2_human RummaGEO Gene Perturbation Signatures 1.0 null Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13243 GSE145990_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE135030_11_v_10_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null heart GTEx Tissue Gene Expression Profiles 1.0 1.52816 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66553 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57512 microtubule COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1283 EXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75232 NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.992364 medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33321 GTEX-XBEC-1226-SM-4AT65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.74816 ITGA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7327 Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BXPC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.177 GSE194396,GSE194429_2_v_0_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null COQ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73815 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles 1.0 0.892866 GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15897 GTEX-XQ8I-0226-SM-4BOPM GTEx Tissue Sample Gene Expression Profiles 1.0 1.37882 mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE252857_2_v_3_prednisone_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.28 hsa-miR-3689b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GARIN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0548 GSE196701_1_v_0_atorvastatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null human immunodeficiency virus infectious disease GWASdb SNP-Disease Associations 1.0 0.740032 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.683978 LRRC59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5471 GSE193258,GSE193259_9_v_0_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null SNU668 CCLE Cell Line Gene CNV Profiles 1.0 1.37507 STAT5A ChEA Transcription Factor Targets 1.0 null frontal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.863009 myofibril COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.721242 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36177 SEPT7 Pathway Commons Protein-Protein Interactions 1.0 null immunodeficiency GWASdb SNP-Phenotype Associations 1.0 0.638927 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.901502 Sarcoma_SARC_TCGA-DX-A7EM-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XYKS-0226-SM-4BRW3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.30368 myoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.260267 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865784 Ornidazole_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0206899 ZNF761 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22225 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF Rummagene Transcription Factor Associations 2026 1.0 null HUWE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06203 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mitochondrial ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.476 GSE145323,GSE145324_9_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null NANS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84451 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.5184 COQ8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51311 PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49906 TP53-22127205-IMR90-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ATF3-27146783-CHIP-SEQ-COLON-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19054 GSE193999,GSE194000_4_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE146982_4_v_2_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null CLASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58445 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09267 UBE2N CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33787 GSE116810_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures 1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4619 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Myofibrillar myopathy 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.093 OAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75812 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884514 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.396725 UBA52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03659 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.51793 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8928 GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14947 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles 1.0 0.84564 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45779 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAKI1 CCLE Cell Line Gene Expression Profiles 1.0 1.57051 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG Rummagene Transcription Factor Associations 2026 1.0 null PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17271 GSE168697_0_v_1_wdr6_mouse RummaGEO Gene Perturbation Signatures -1.0 null preoptic telencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15814 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.05622 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055149 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9588 ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7939 OXLD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28609 PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 ZNF263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6273 SYF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47305 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null ZNF74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31935 HCC2935 CCLE Cell Line Gene CNV Profiles -1.0 -1.67727 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.870833 GSE216757_4_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Plantaris muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.242 GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.945504 GTEX-S7SF-0526-SM-3K2BC GTEx Tissue Sample Gene Expression Profiles 1.0 2.30709 Cardiomyopathy, Hypertrophic HuGE Navigator Gene-Phenotype Associations 1.0 null GSE210101,GSE210114_7_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null second (ventral) preoptic domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14434 CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18455 postcentral gyrus, right, bank of the central sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14711 H3K36me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Intercalated disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.515 GSE119498_0_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles 1.0 0.933739 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900925 INA6 DepMap CRISPR Gene Dependency 1.0 2.62208 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.951886 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28927 HCC2218 CCLE Cell Line Gene CNV Profiles 1.0 1.62132 GSE149901_2_v_1_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STYXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93348 GSE142684_4_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0916 GSE226408_2_v_3_inpp4b_human RummaGEO Gene Perturbation Signatures 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03392 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.5896 PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.42629 TIMM50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50593 ZNF585A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58656 UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78125 H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM54 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10447 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Sleeping sickness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.645 SARNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59848 BT12 DepMap CRISPR Gene Dependency 1.0 3.36617 ATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00725 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-3679-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.763 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4A Pathway Commons Protein-Protein Interactions 1.0 null CDCA7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61215 GSE233679_14_v_13_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null HDAC3_KO_GDS4886_66_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 RRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63911 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-650 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GSE219274,GSE219276_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 1.13804 GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15402 SPOUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38274 GSE111385_2_v_1_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE238018_1_v_4_mxra8_human RummaGEO Gene Perturbation Signatures -1.0 null SHLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24847 DCUN1D5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82637 FAM50B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73755 SPO11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23105 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8543 r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56792 SAV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1199 Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 mRNA_WHSC2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 0.895315 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8321 Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null METTL7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88016 VDAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10976 Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.946147 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cardiac muscle TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TAGLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64263 ARNT ChEA Transcription Factor Targets 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.904493 GSE207514,GSE207515_0_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08239 GTEx Thyroid 20-29 vs 60-69 GTEx Tissue-Specific Aging Signatures 1.0 6.15339 Type 1 diabetes mellitus_T lymphocyte_GSE10586 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.39394 ZNF479 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9709 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04212 GTEX-WL46-0926-SM-3LK7T GTEx Tissue Sample Gene Expression Profiles 1.0 1.0196 786-O Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95341 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.84397 Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16933 CHST14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80115 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG Rummagene Transcription Factor Associations 2026 1.0 null HINFP JASPAR Predicted Transcription Factor Targets 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32203 TAL1 ChEA Transcription Factor Targets 1.0 null RKN COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-106a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 GTEX-WQUQ-1426-SM-3MJFD GTEx Tissue Sample Gene Expression Profiles 1.0 0.827807 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28249 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.057136 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35263 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles 1.0 1.1076 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null ZNF878 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11207 SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null HS3ST3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93463 MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20531 protein binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PABPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72263 UBE4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6429 PBX1 ChEA Transcription Factor Targets 1.0 null ZNF669 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50924 MINPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15663 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840727 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.176305 GTEX-X4XX-1126-SM-3NMBY GTEx Tissue Sample Gene Expression Profiles 1.0 0.889136 GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 1.32597 GTEX-OIZH-0326-SM-2HMKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.28472 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.69188 REXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02424 GSE176555,GSE176556_1_v_0_acriflavine_human RummaGEO Drug Perturbation Signatures 1.0 null Liver Diseases CTD Gene-Disease Associations 1.0 1.11255 superficial stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2337 GSE111385_0_v_1_tgfbr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null breast HPA Tissue Protein Expression Profiles -1.0 -0.748185 Lung adenocarcinoma_LUAD_TCGA-93-7347-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21183 RMC-6236_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0193517 TPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62728 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.902809 ARNT-22903824-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MEGF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74536 PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1 Rummagene Transcription Factor Associations 2026 1.0 null PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE135030_3_v_2_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Tou TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.612 USPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86245 GTEX-R55E-1026-SM-2TC5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.23818 EP300_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE233679_5_v_7_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null AZD-7648_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0252556 PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC Rummagene Transcription Factor Associations 2026 1.0 null TDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66024 HEG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90283 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12517 GTEX-OIZG-1126-SM-2HMIU GTEx Tissue Sample Gene Expression Profiles 1.0 0.85676 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null CSNK2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86025 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles 1.0 2.21102 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BL-70 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flexor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.373 TCF12_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X3Y1-0426-SM-3P5Z4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19704 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.16256 Hypertrophic Cardiomyopathy DisGeNET Gene-Disease Associations 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 0.895445 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.996415 Field CA2, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61504 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 2.01567 HDAC6 ENCODE Transcription Factor Targets 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles 1.0 1.57689 TNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07636 cardiovascular system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2348 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE223008_9_v_2_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null ARAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68166 POU3F2 ChEA Transcription Factor Targets 1.0 null GSE233679_14_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.17761 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles 1.0 0.837286 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3425-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.76073 TSC22D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69558 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44653 TOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56106 PMC8639061-pcbi.1009563.s014.xlsx-ST4-S4_Table_Phenotypic_master_regulator_MR_list_with_pleiotropy_count_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38971 GSE248045,GSE248046_0_v_5_runx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null nucleus LOCATE Curated Protein Localization Annotations 1.0 null Lung adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 SMAD5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1786 SEPTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9302 496100634_HIP_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30694 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.281 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3043_KD_Ppp1r13l_ERP023515 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.01164 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.19409 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059728 cytoplasm GO Cellular Component Annotations 2015 1.0 null POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7402 lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53696 Ligustrazine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0223179 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04212 Supramolecular polymer COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 ENSG00000170846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69918 GTEX-QDVJ-0426-SM-2I5FW GTEx Tissue Sample Gene Expression Profiles 1.0 1.51411 PDZD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76738 finger TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.896895 20081105-ST-2 GeneSigDB Published Gene Signatures 1.0 null Striated muscle thin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.519 III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3394 GSE142684_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null USP6NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31602 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2052 DepMap CRISPR Gene Dependency 1.0 10.9958 MRK-NU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3358 FKRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59512 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3488 GTEX-SJXC-1226-SM-4DM78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03593 PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC Rummagene Transcription Factor Associations 2026 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.227397 EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.02079 Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.016 heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.310421 CLIC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06341 ANHX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25832 L428 CCLE Cell Line Gene Expression Profiles 1.0 2.4915 PTGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30306 Perturb_14090_KO_SMARCA4_SRP295674 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1 Rummagene Transcription Factor Associations 2026 1.0 null LAMA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25895 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null UCHL3 Pathway Commons Protein-Protein Interactions 1.0 null PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Table_S6_Overlap_of_differentially_expressed_genes_in_Tg_HSP_EWS-FLI1_embryos_and_human_EWS-FLI1_signature_from_Smith_et_al_2006_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31016 GSE120370_4_v_1_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9678 GSE135030_11_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.40038 dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22297 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TBP_TBP Rummagene Transcription Factor Associations 2026 1.0 null VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.958689 CLCN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71111 SLC7A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77075 superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08436 GALNT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8805 CHPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99921 EGR1 ENCODE Transcription Factor Targets 1.0 null DMRTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34985 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9233 G3BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3421 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.14864 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.2479 Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 SEC61A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85181 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860583 MYOD1_myocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01998 POMGNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21545 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14689 PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP Rummagene Transcription Factor Associations 2026 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11703355-IEPI_A_2435244_SM8871.xlsx-Table_S2-KMT2B_T_K_KMT2B Rummagene Transcription Factor Associations 2026 1.0 null MDM4 Pathway Commons Protein-Protein Interactions 1.0 null NOMO1 DepMap CRISPR Gene Dependency 1.0 6.67447 ZNF354B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55048 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE225901_2_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null TENM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30462 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.70696 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048988 BUD31 Pathway Commons Protein-Protein Interactions 1.0 null RPS6KA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41856 hsa-miR-3689a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 LPS6 DepMap CRISPR Gene Dependency 1.0 5.21728 Proventriculus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.76 NMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23488 CYB5R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42631 H2AL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28258 mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66485 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null myoblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.262304 ACOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52265 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835854 GSE146247_0_v_1_sirt7_human RummaGEO Gene Perturbation Signatures 1.0 null Mitochondrial mRNA editing complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.706 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.7257 Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10565 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles 1.0 1.15351 GTF2I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04458 HEC50B CCLE Cell Line Gene Expression Profiles 1.0 1.36188 GSE203485_1_v_0_zdhhc2_human RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease Susceptibility HuGE Navigator Gene-Phenotype Associations 1.0 null TOMM34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7393 Brain Lower Grade Glioma_LGG_TCGA-QH-A65V-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BSPRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82643 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10674 HMX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16468 Myosin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.872 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1184 CCLE Cell Line Gene Expression Profiles -1.0 -1.59172 Trypomastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.861 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17708 USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null adrenal gland HPA Tissue Gene Expression Profiles -1.0 -1.61077 PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null rhombomere 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02385 TEPSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89934 PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null DDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48121 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07318 GLYATL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60813 SKMM2 CCLE Cell Line Gene Expression Profiles 1.0 1.72386 GJA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32838 PDHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41955 KSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36967 hsa-miR-20b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GEMIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39032 PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null PNMA8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84107 PRDM14-20953172-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Left ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.079 LFNG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19775 GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles 1.0 1.14931 H3K79me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.0406 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 0.892711 viral infectious disease GWASdb SNP-Disease Associations 1.0 0.226692 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.213291 BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5489 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06575 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 RNF225 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48202 GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles 1.0 1.30658 ANKRD13C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55664 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.834736 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.970423 SNX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43547 CACNG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50749 ZNF831 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65867 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52872 GTEX-O5YT-0326-SM-32PKA GTEx Tissue Sample Gene Expression Profiles 1.0 1.28773 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11409 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLCO4A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9602 Flight muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.613 SRF ChEA Transcription Factor Targets 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 0.895164 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NJ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pravastatin (sodium)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0229462 CDK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96296 USF1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71648 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16855 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.397 GTEX-OIZF-1526-SM-3MJGY GTEx Tissue Sample Gene Expression Profiles 1.0 1.31018 Perturb_8898_KD_IGF2BP1_SRP359044 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.76226 UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66679 IGROV1 DepMap CRISPR Gene Dependency 1.0 5.42125 H3K9me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE169205_3_v_2_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.279 seed TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066403 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles 1.0 0.991571 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ubiquitin-protein transferase activity GO Molecular Function Annotations 2025 1.0 null GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39374 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217694_4_v_0_pold1_mouse RummaGEO Gene Perturbation Signatures 1.0 null plumule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071729 ZNF70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80549 NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.32143 GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27167 Masseter TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.569 KRTCAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36368 CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.4201 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17238 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05159 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.905101 skeletal muscle HPA Tissue Gene Expression Profiles 1.0 0.96982 ubiquitin-like protein ligase activity GO Molecular Function Annotations 2023 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01506 ALG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58974 CFAP97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43278 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.09966 oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05527 CIPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07454 hsa-miR-93 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 r8 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06359 Danon disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64434 mantle zone of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28841 Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.242 PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3 Rummagene Transcription Factor Associations 2026 1.0 null KD DepMap CRISPR Gene Dependency 1.0 4.10592 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null USP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62768 PRPF19 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X261-0926-SM-3NMCY GTEx Tissue Sample Gene Expression Profiles 1.0 1.07613 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09794 GTEX-XPVG-0726-SM-4B658 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27635 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BAIAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.301 GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles 1.0 1.05936 decreased heart rate IMPC Knockout Mouse Phenotypes 1.0 null PMC9899501-NIHMS1869252-supplement-Table_S4.xlsx-REACTOME_UP_2_5-HAND1_HAND1 Rummagene Transcription Factor Associations 2026 1.0 null CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH522 CCLE Cell Line Gene CNV Profiles -1.0 -2.13094 MLF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86597 GTEX-S32W-0626-SM-2XCBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.20996 LAMC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21161 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.93796 superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03993 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879642 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853838 GSE131161_3_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Amastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 ELF5-23300383-T47D-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE217363_5_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928886 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Z-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17884 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 0.886995 SLC45A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20552 E2F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11386 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80217 POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intrinsic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.84 MRPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77974 PDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00675 GSE223893_2_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null PRKCA_knockdown_118_GSE27869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.76057 GSE164874_5_v_4_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null r6 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21607 Contractile fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.187 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3187 GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles 1.0 0.900074 NENF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83874 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Vici syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.293 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7235 HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23374 Z disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.076 WASL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22997 GTEX-XQ3S-0526-SM-4BOQA GTEx Tissue Sample Gene Expression Profiles 1.0 1.86441 hsa-miR-3140-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 TMEM256 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62057 mantle zone of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33624 bj HPA Cell Line Gene Expression Profiles 1.0 1.18438 GSE134375_4_v_7_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE152937_12_v_1_slc16a13_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAN2C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49433 CDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37921 NCIH684 CCLE Cell Line Gene Expression Profiles -1.0 -2.1524 cardiovascular system phenotype MPO Gene-Phenotype Associations 1.0 null GSE137702_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null MTRF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47325 GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles 1.0 1.12496 Perturb_261_KD_PBRM1_SRP358304 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PNPLA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9134 Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01992 SNU398 DepMap CRISPR Gene Dependency 1.0 2.38457 anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.98341 Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10132 ABL1_knockdown_144_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.80369 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.87159 GI1 CCLE Cell Line Gene Expression Profiles 1.0 1.64129 SH3GL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0975 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles 1.0 0.952957 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.912167 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.8895 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null GTEX-T6MN-0926-SM-32PLX GTEx Tissue Sample Gene Expression Profiles 1.0 1.30979 cardiac hypertrophy MGI Mouse Phenotype Associations 2023 1.0 null intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27541 HS-578-T COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 GSE135030_11_v_5_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null MGAT4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09023 PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Gene_Name_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null FXYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68972 GSE143944_2_v_3_ribociclib_human RummaGEO Drug Perturbation Signatures 1.0 null PNKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53877 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.06 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.936307 JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE164874_5_v_6_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null CORO2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23119 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67258 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09081 Spinal nucleus of the trigeminal, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19852 ZNF169 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12441 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4724 Phenytoin (sodium)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.016891 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.33913 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles 1.0 0.883414 Vesicular gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.634 HS6ST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01205 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Inclusion body myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.151 ELP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69778 r8 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19852 Superior colliculus, motor related, intermediate gray layer, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39996 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928175 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRAP Pathway Commons Protein-Protein Interactions 1.0 null MRPL55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67775 RAB2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38721 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3863 hsa-miR-129-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.971288 frhk4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 TNNI2 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31605 SW1271 DepMap CRISPR Gene Dependency 1.0 2.30232 GSE112995,GSE132079_1_v_0_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null SOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5664 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86977 Perturb_5988_KD_ZNF207_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XOT4-1126-SM-4B66E GTEx Tissue Sample Gene Expression Profiles 1.0 1.94956 PMC7488531-13287_2020_1914_MOESM10_ESM.xlsx-HNF4A_regulated_DEGs_750-Unnamed_1_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SLC25A34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84461 Feather vane TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.677 Sarcoma_SARC_TCGA-DX-A8BU-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-0526-SM-2I3ED GTEx Tissue Sample Gene Expression Profiles 1.0 1.27905 Belzutifan_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0213799 ZNF425 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09409 TCAIM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3447 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960614 GSE135030_8_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null NANOGNB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45501 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESR1-20079471-T-47D-HUMAN ChEA Transcription Factor Targets 2022 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28171 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44201 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.159074 PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null Leg muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.704 Organellar small ribosomal subunit COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.356 Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.28 BV-173 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.33194 Muscular system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14255 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6623 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.933332 Futibatinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0036225 z disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.231315 identical protein binding GO Molecular Function Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.951254 COQ10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01904 BAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77792 GTEX-XUJ4-0626-SM-4BOOO GTEx Tissue Sample Gene Expression Profiles 1.0 1.36538 GSE158738_0_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null FABP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01692 CBLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71516 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196339 NPAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47334 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.742 AP3M2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45016 hsa-miR-219-1-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 SEC23IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47641 UCHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91827 r9 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2337 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SNX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75372 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21177 KIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91674 hsa-miR-4755-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.08903 STRA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8907 TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null PCNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32272 VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51985 GSE74251_0_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95115 arm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.836156 hsa-miR-3184 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Perturb_14120_OE_TINCR_SRP182819 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.0458 GTEX-QV44-0526-SM-2S1RE GTEx Tissue Sample Gene Expression Profiles 1.0 1.28755 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE131649_2_v_9_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null DLST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75714 GSE242367_1_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68972 PRICKLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31379 pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26566 EGR4_01_132 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.14866 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE131649_6_v_9_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null Myotonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 hsa-miR-4260 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 SCS214 DepMap CRISPR Gene Dependency 1.0 2.32031 GSE125219,GSE125221_5_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-9 TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 c2c12 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.333028 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles 1.0 0.903894 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.984726 Opitz GBBB syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.41 PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1 Rummagene Transcription Factor Associations 2026 1.0 null H2BK12ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NEU3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2469 Cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.769 CDK5RAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78478 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.926409 GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles 1.0 2.52775 Perturb_8695_KO_Stat1_SRP364338 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 positive regulation of intracellular signal transduction GO Biological Process Annotations 2025 1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28202 cation binding GO Molecular Function Annotations 2015 1.0 null USP39 Pathway Commons Protein-Protein Interactions 1.0 null TR146 DepMap CRISPR Gene Dependency 1.0 3.07855 sirolimus_homo sapiens_gpl6244_gse15703 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZNF678 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34909 Larotrectinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0244643 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.887859 GTEX-RWSA-0626-SM-2XCBD GTEx Tissue Sample Gene Expression Profiles 1.0 0.982141 mantle zone of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48319 SUDHL10 DepMap CRISPR Gene Dependency 1.0 2.31052 GSE88819_11_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.060882 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29866 PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG Rummagene Transcription Factor Associations 2026 1.0 null r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0594 Congenital myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.31 C4II DepMap CRISPR Gene Dependency 1.0 2.01433 TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 I band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.042 TAMALIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55921 GSE119978,GSE180930_2_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 GSE174701_4_v_0_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 Foot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.973 ALKBH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75387 metal ion binding GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AM38 DepMap CRISPR Gene Dependency 1.0 7.80715 hsa-miR-4311 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 TCF21-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TNNC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92684 SCL-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SORD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86667 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.44755 KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77669 abnormal skeletal muscle mass MPO Gene-Phenotype Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Belzutifan_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0214491 Vertebrate muscular system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_3687_KD_RARRES2_SRP287866 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.93548 GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE111385_2_v_3_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE173169,GSE173170_0_v_1_epc2_human RummaGEO Gene Perturbation Signatures -1.0 null NR2E3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13236 ZSCAN20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65085 CYB5R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38376 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834055 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2887 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DGCR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51886 DUXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93697 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.101 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.289 GSE119978,GSE180930_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41644 biological_process GO Biological Process Annotations 2015 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839801 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2646 ADAMTS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64832 TGIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28901 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04701 HDAC3_KO_GDS4886_29_mouse_heart - 6 week old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LCLC103H CCLE Cell Line Gene Expression Profiles -1.0 -1.83806 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 19658189-TableS3 GeneSigDB Published Gene Signatures 1.0 null CEBPZOS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45379 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.568 Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE150349_0_v_1_msx1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF575 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29915 K2 COSMIC Cell Line Gene Mutation Profiles 1.0 null MCIXC DepMap CRISPR Gene Dependency 1.0 2.01139 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5368 Perturb_6608_KO_STK11_ERP124775 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.8777 PLPBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89867 superficial layers of TG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22466 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null FAM162A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3132 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1177 C11orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12955 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.951445 Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DHX9 Pathway Commons Protein-Protein Interactions 1.0 null APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.57162 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02338 HIV Infections HuGE Navigator Gene-Phenotype Associations 1.0 null EPM2AIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19005 Perturb_11860_KO_lincFoxf1a_SRP028547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.75015 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25202 C21orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30445 HARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20263 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078683 Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.43101 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null GSE203072_2_v_3_rpl3l_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.5515 Heart ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.079 TMEM259 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49761 GTEX-OOBJ-0326-SM-33HBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.3148 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064516 biological regulation GO Biological Process Annotations 2015 1.0 null UBE2I Hub Proteins Protein-Protein Interactions 1.0 null GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.5186 Procyclic form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.097 GSE203485_1_v_0_sunitinib_human RummaGEO Drug Perturbation Signatures -1.0 null inferior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906658 MONOMAC6 CCLE Cell Line Gene Expression Profiles -1.0 -2.00422 GTEX-WYJK-1126-SM-3NM9Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.30463 Heart TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Ubiquitin activating enzyme complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.962 lateral part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7091 GSE155695,GSE155696_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null mc86 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.599 NCI-H1975 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865784 NKX2-5-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3378 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null CADOES1 CCLE Cell Line Gene CNV Profiles 1.0 1.5791 intermediate stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17912 TP53-18474530-U2OS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE100316_5_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.9646 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5078 NOLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81065 positive regulation of non-canonical NF-kappaB signal transduction GO Biological Process Annotations 2025 1.0 null POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.02641 PGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13476 FLOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06219 GTEX-PX3G-0326-SM-2I3EO GTEx Tissue Sample Gene Expression Profiles 1.0 1.24164 TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null TOMM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61215 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928175 SETD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.63873 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAZ1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55682 periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09144 parenchyma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.786468 KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Arrhythmogenic right ventricular cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.231 Lung adenocarcinoma_LUAD_TCGA-44-2668-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11601_KD_ABCD4_SRP113334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.40884 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87037 Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMNB1_02_195 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63524 TSHZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42932 EPCAM_OE_GDS4887_343_human_IL-28B GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Myotome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.7 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01506 GSE223008_9_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null KE39 CCLE Cell Line Gene CNV Profiles 1.0 1.51747 GTEX-S32W-1926-SM-4AD63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83769 leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072773 ESET-19884257-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.809298 abnormal heart size MPO Gene-Phenotype Associations 1.0 null METTL23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93219 IGFBPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6322 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05001 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.395608 SMIM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61262 superior parietal lobule, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.86442 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null microtubule cytoskeleton GO Cellular Component Annotations 2025 1.0 null PMC9008061-41467_2022_29733_MOESM4_ESM.xlsx-ERRg_SE_peaks-Nearest_Ensembl_ESRRG Rummagene Transcription Factor Associations 2026 1.0 null Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17057 Skeletal muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.419 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 2.0038 IA-LM COSMIC Cell Line Gene Mutation Profiles 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10485 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFSD14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1538 Intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 OVK18 CCLE Cell Line Gene Expression Profiles -1.0 -1.74729 NAAA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45583 Retrosplenial area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.27023 Quadriceps TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.39 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31441 GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49906 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06797 disease by infectious agent GWASdb SNP-Disease Associations 1.0 0.14402 C2BBE1 DepMap CRISPR Gene Dependency 1.0 2.8202 Bed nuclei of the stria terminalis, posterior division, transverse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.88534 GSE193258,GSE193259_9_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null NAA40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.71521 Mitral valve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 SYVN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98884 GSE155972_0_v_1_setdb1_human RummaGEO Gene Perturbation Signatures 1.0 null KIF14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05257 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null spleen HPA Tissue Gene Expression Profiles -1.0 -1.23116 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0526-SM-2I3ER GTEx Tissue Sample Gene Expression Profiles 1.0 2.07111 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFYVE27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62777 signal transducer activity GO Molecular Function Annotations 2015 1.0 null GSE153867_6_v_4_olaparib_human RummaGEO Drug Perturbation Signatures -1.0 null GSC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95975 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GMIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88218 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.833286 MID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06925 EIF3K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23091 UBE2D2 Pathway Commons Protein-Protein Interactions 1.0 null GSE205163,GSE205164_1_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0961 RB1_KD_GSE50532_654_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null JEG3 DepMap CRISPR Gene Dependency 1.0 3.88961 heart muscle HPA Tissue Gene Expression Profiles 1.0 1.83702 AHR ChEA Transcription Factor Targets 1.0 null GSE164874_5_v_1_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null Muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.445 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null TFE3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0236 Perturb_293_KO_GPX4_SRP255715 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.1549 PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG Rummagene Transcription Factor Associations 2026 1.0 null PEA15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67979 r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49906 GSE239844_11_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null MFE-296 COSMIC Cell Line Gene Mutation Profiles 1.0 null cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CAL33 CCLE Cell Line Gene CNV Profiles 1.0 1.5721 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91853 PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A Rummagene Transcription Factor Associations 2026 1.0 null Pallidum, caudal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68547 TMEM234 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94809 GSE178267_2_v_0_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39992 GSE213228_4_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93636 GSE217694_3_v_0_pold1_mouse RummaGEO Gene Perturbation Signatures 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970878 GTEX-XLM4-2026-SM-4AT4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.46528 GTEX-WH7G-0326-SM-3NMBH GTEx Tissue Sample Gene Expression Profiles 1.0 1.55632 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE173810_0_v_1_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HMGN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08779 EEF1G Pathway Commons Protein-Protein Interactions 1.0 null zinc ion binding GO Molecular Function Annotations 2015 1.0 null NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2016 GSE184356_3_v_0_tfam_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-GSE131737_TFAP2B_target_genes_G_gallus_1347_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null retropontine reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09717 Bacteroid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.966 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.19893 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.50599 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.93622 FOXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87254 GSE142684_2_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE184892_4_v_2_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null GCLM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49046 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles 1.0 0.942687 hsa-miR-133a TargetScan Predicted Conserved microRNA Targets 1.0 0.154935 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.860731 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02385 layer 2 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02902 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles 1.0 0.838067 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.039733 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 FOXP2-23625967-PFSK-1-AND-SK-N-MC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Anterior cingulate area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.22109 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null SGC-7901 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.701 ESR1 ChEA Transcription Factor Targets 1.0 null MMS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05468 GSE157282_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10596 GTEX-WFG7-0826-SM-3GIKU GTEx Tissue Sample Gene Expression Profiles 1.0 1.31343 LBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56337 GSE131649_6_v_8_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16945 Zinc finger, B-box InterPro Predicted Protein Domain Annotations 1.0 null GSE88819_6_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYL2 Pathway Commons Protein-Protein Interactions 1.0 null GSE213228_4_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null PARP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41659 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08696 Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GUSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42976 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.696581 GSE131377_4_v_2_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null urinary system disease GWASdb SNP-Disease Associations 1.0 0.22142 GSE139975_3_v_0_rnf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE131649_4_v_9_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-RU72-1426-SM-46MUF GTEx Tissue Sample Gene Expression Profiles 1.0 0.944432 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06731 temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.19497 UBE2D3 Pathway Commons Protein-Protein Interactions 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24995 Skeletal system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hsa-miR-190b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Skeletal muscle fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.35 lymph node HPA Tissue Protein Expression Profiles -1.0 -0.748185 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 0.911579 PYGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20974 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null procyclic form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.19311 mantle zone of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14434 nucleus GO Cellular Component Annotations 2015 1.0 null CA9-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24709 hsa-miR-370 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 SSH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38294 AMOTL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01355 HIBADH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83565 PC14 CCLE Cell Line Gene CNV Profiles -1.0 -1.36996 STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF469 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9927 GSE207122_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52781 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87485 Proteasome core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.161 GTEX-OOBJ-0826-SM-3NB2K GTEx Tissue Sample Gene Expression Profiles 1.0 0.903371 ZUP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56553 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null ZNF844 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56213 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Trifluridine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0197357 hsa-miR-362-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 DNMT3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04158 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE216757_0_v_2_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Myotube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.602 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0512 TP53 ChEA Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.165 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.6622 FKBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55283 EIF4G1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91695 decitabine_homo sapiens_gpl570_gse30985 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCSTN Pathway Commons Protein-Protein Interactions 1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.983114 FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86586 ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null Atrium TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.059 POTEI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90059 ZNF426 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45931 GSE135030_8_v_2_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE203181_0_v_1_phosphoramidon_human RummaGEO Drug Perturbation Signatures -1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.69079 mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NCI-H1975 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.532 PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PSDG-0926-SM-2I5FP GTEx Tissue Sample Gene Expression Profiles 1.0 0.939492 Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59623 ENTPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26604 GTEX-XPT6-0226-SM-4B65L GTEx Tissue Sample Gene Expression Profiles 1.0 1.30369 Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89756 Trypanosomiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.545 GSE139016_0_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.863615 primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.217 Npas2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4797 Cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null increased skeletal muscle fiber size MGI Mouse Phenotype Associations 2023 1.0 null GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.999845 SNU620 CCLE Cell Line Gene Expression Profiles -1.0 -1.49863 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.3614 primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25347 ZNF384_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_02_192 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.66626 Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC827 CCLE Cell Line Gene CNV Profiles 1.0 3.23671 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10141 PCCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82611 Polymeric cytoskeletal fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC Rummagene Transcription Factor Associations 2026 1.0 null PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Unnamed_3_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NHLRC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50583 DPY19L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53082 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 5.8127 SPRY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52003 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.157397 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null SEC31B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25044 CCDC163 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28846 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 0.85045 RAB11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13226 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.509027 PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1 Rummagene Transcription Factor Associations 2026 1.0 null NCSTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08746 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 BI-78D3_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0162606 TRIM27 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32692 Facioscapulohumeral muscular dystrophy 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 THAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33347 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 0.89588 H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EFNA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83218 r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07318 PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5 Rummagene Transcription Factor Associations 2026 1.0 null NUDT19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20843 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.848526 PMC9008061-41467_2022_29733_MOESM4_ESM.xlsx-ERRg_SE_peaks-Gene_Name_ESRRG Rummagene Transcription Factor Associations 2026 1.0 null DLX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34453 GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.919548 Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49373 HES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7924 PPP2R2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.20969 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19676 GSE119978,GSE180930_6_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE112860_5_v_8_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null NGFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63267 C2CD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42816 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MLF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53728 mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15539 H2BK15ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GATA2_01_193 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59793 medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18795 TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5901 CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZDHHC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94004 GSE178255_1_v_6_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4489 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ADRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63127 PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Promastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.021 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.951445 SIVA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29925 SNRNP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33348 CGGBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66713 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34077 Docetaxel_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0194901 NID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2043 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14616 FOXP2 ENCODE Transcription Factor Targets 1.0 null SLC4A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05895 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06731 GSE139016_3_v_2_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.854383 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null medial part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01491 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null r9 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48319 hsa-miR-330-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 USF1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null TSPAN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75252 FXYD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09129 GSE135030_8_v_6_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2073 FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE138863_3_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null TRIM63 Pathway Commons Protein-Protein Interactions 1.0 null GSE190316,GSE190324_1_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null BT483 CCLE Cell Line Gene CNV Profiles 1.0 1.36371 hsa-miR-4422 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 hsa-miR-1302 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.97781 RCOR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84112 GSE233679_12_v_2_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE262134_0_v_1_dnajc12_human RummaGEO Gene Perturbation Signatures 1.0 null BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68098 GTEX-X3Y1-0226-SM-3P5Z5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48055 METTL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41421 GSE149880_2_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15539 CEP131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20703 EBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -0.748185 GSE132948,GSE132949_2_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE228106_3_v_1_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null NCI-H835 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XBP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3453 TSC22D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70989 DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59472 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00659 increased heart weight MGI Mouse Phenotype Associations 2023 1.0 null GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03775 Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226249_2_v_7_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null Extrinsic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 CUL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4263 Crizotinib (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0241057 LOXIMVI COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles 1.0 1.2065 DCUN1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16985 H3K4me1_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null GSE183041_1_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE242083,GSE242098_2_v_1_med1_human RummaGEO Gene Perturbation Signatures 1.0 null rh30 HPA Cell Line Gene Expression Profiles 1.0 1.62363 GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null CCAR1 Pathway Commons Protein-Protein Interactions 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.977583 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null SRF_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15219 GSE104022_3_v_4_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null Omegasome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.765 GTEX-WHPG-1026-SM-3NMBA GTEx Tissue Sample Gene Expression Profiles 1.0 1.48361 Vastus lateralis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.078 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3-24758297-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null supraventricular tachycardia GWASdb SNP-Phenotype Associations 1.0 0.434952 heart_5b HPA Tissue Sample Gene Expression Profiles 1.0 1.33682 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08436 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71105 EWS-ERG-20517297-CADO-ES1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ATF3 ChEA Transcription Factor Targets 1.0 null PYGB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84002 GSE190316,GSE190324_1_v_11_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null Hepatitis A DisGeNET Gene-Disease Associations 1.0 null Endocardial heart tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.23 GPR108 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44459 LRP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44991 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840727 496100671_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.09533 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kinetoplastid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.286 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8911 abnormal skeletal muscle fiber morphology MPO Gene-Phenotype Associations 1.0 null BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.881 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FUS_02_155 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.5025 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128844_0_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null MAN2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89868 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50327 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22532 ABCF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58469 Asciminib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0313387 CKAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48829 GSE160765_2_v_1_twist1_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-494 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE100316_5_v_4_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null SPRYD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43304 GSE131649_2_v_8_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null CTTNBP2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0107 KG1 CCLE Cell Line Gene CNV Profiles 1.0 2.25443 PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR Rummagene Transcription Factor Associations 2026 1.0 null POU5F1_01_95 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.41192 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11196 Sarcoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.223 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86129 ZNF492 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43989 Bed nuclei of the stria terminalis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69102 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sertoli cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null MACIR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41583 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles 1.0 0.951533 CLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05811 ANKRD50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83032 JcP contribution to LTL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03993 Congenital myopathy 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.167 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE122215,GSE122217_0_v_4_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE216273,GSE216292_14_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null SEZ6L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33399 Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF454 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22296 PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB Rummagene Transcription Factor Associations 2026 1.0 null FOSL2_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE99875_2_v_0_everolimus_human RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69582 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884514 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.4245 CKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98422 MDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24321 BCL2L13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17591 Perturb_5574_KO_NFKBIA_SRP149723 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.5998 NFE2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44945 GTEX-XPT6-0126-SM-4B65S GTEx Tissue Sample Gene Expression Profiles 1.0 1.19003 Perturb_13560_OE_Kdm1a_SRP105108 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.08215 PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-6545-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DHCR24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85564 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles 1.0 0.970266 NDST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05848 r9 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49906 MAFK_02_183 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.67807 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843275 protein polyubiquitination GO Biological Process Annotations 2025 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840727 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28991 TGIF MotifMap Predicted Transcription Factor Targets 1.0 null H2AC19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47255 QTRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59371 KLF1 ChEA Transcription Factor Targets 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0826-SM-2HML4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07497 mantle zone of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6444 MSRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60459 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45687 GSE186460_0_v_2_baricitinib_human RummaGEO Drug Perturbation Signatures -1.0 null vascular bundle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.143013 microtubule GO Cellular Component Annotations 2023 1.0 null Septic Shock_Whole blood_GSE9692 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.53864 abnormal heart morphology MPO Gene-Phenotype Associations 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997148 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1518 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.911485 GSE108084_3_v_2_epinephrine_human RummaGEO Drug Perturbation Signatures -1.0 null liver_a HPA Tissue Sample Gene Expression Profiles 1.0 0.934962 r3 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0277 SF3B3 Pathway Commons Protein-Protein Interactions 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.090893 subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.039 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.838 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.795 IRF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40249 P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.357 U-CH2 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null Tibialis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.443 PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711 Rummagene Transcription Factor Associations 2026 1.0 null Bed nuclei of the stria terminalis, anterior division, ventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.24292 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bone marrow HPA Tissue Gene Expression Profiles -1.0 -0.872908 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31306 Cytoskeleton in muscle cells KEGG Pathways 2026 1.0 null mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840021 hsa-miR-4272 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles 1.0 1.03488 PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1 Rummagene Transcription Factor Associations 2026 1.0 null limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19829 COS domain InterPro Predicted Protein Domain Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYOD1 ENCODE Transcription Factor Targets 1.0 null HES3_KD_GSE64449_187_mouse_Min6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.489057 membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null CUX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8236 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63333 GSE135030_8_v_5_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null Niclosamide (olamine)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0174062 Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.099746 GTEX-WZTO-1326-SM-3NM8X GTEx Tissue Sample Gene Expression Profiles 1.0 1.24125 cardiac hypertrophy MPO Gene-Phenotype Associations 1.0 null GSE149880_0_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17794 BCL7C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40929 H3C11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28571 METTL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.162 GTEX-WL46-0726-SM-3LK5Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.30051 hsa-miR-4699-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GPR137 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9252 hsa-miR-635 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 r4 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18401 Lateral vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00093 GSE132369,GSE132371_2_v_0_cccp_human RummaGEO Drug Perturbation Signatures -1.0 null SKMM2 CCLE Cell Line Gene CNV Profiles 1.0 1.66673 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68755 NDUFS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09986 chr8_66200592_A_G_b38 GTEx eQTL 2025 1.0 1.11462 SDCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11762 MEF2A-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19897 SERF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5669 TMEM250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67885 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08174 decreased fasting circulating glucose level IMPC Knockout Mouse Phenotypes 1.0 null GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles 1.0 0.996106 USF1 ENCODE Transcription Factor Targets 1.0 null sarcomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.785071 USF1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Muscular atrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.581 GSE88819_11_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4514 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.85786 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 0.831351 hsa-miR-3619-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GTEX-WRHU-1026-SM-4E3ID GTEx Tissue Sample Gene Expression Profiles 1.0 1.9851 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.979335 ARNT_01_315 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59617 GSE246184,GSE246195_0_v_1_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Sarcoglycan complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 SLAIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58844 ZFX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86602 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE149880_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null X-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 GFI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07313 cervix, uterine HPA Tissue Protein Expression Profiles -1.0 -0.748185 OVTOKO DepMap CRISPR Gene Dependency 1.0 6.7428 SOX9-26525672-CHIP-SEQ-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Troponin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.519 microtubule GO Cellular Component Annotations 2025 1.0 null CAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77648 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22401 microtubule GO Cellular Component Annotations 2015 1.0 null MYOD1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-423-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE9377_GENE_AR Rummagene Transcription Factor Associations 2026 1.0 null peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32979 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLR21 CCLE Cell Line Gene Expression Profiles 1.0 1.41514 Tibial muscular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.419 GSE210101,GSE210114_11_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null PGAM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98235 EWS-ERG-20517297-CADO-ES1-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD3-18955504-HACAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null JAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46492 GATA4-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sarcoma_SARC_TCGA-IW-A3M6-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205976,GSE205978_3_v_5_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null Kinetoplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.058 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3029 CFAP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3485 Busulfan_MIA PaCa-2 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0163401 GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18942 NPAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45693 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2257 SPTLC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70369 TE14 CCLE Cell Line Gene Expression Profiles -1.0 -1.91387 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WK11-0626-SM-3NMAV GTEx Tissue Sample Gene Expression Profiles 1.0 1.46537 GTEX-SIU8-0826-SM-2XCDQ GTEx Tissue Sample Gene Expression Profiles 1.0 2.54961 AHR-22903824-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RET_druginhibition_184_GSE49414 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -5.34882 periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61504 GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913948 STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null HT55 DepMap CRISPR Gene Dependency 1.0 2.02872 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDK4_knockdown_143_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.43873 GTEX-U8XE-1126-SM-3DB8W GTEx Tissue Sample Gene Expression Profiles 1.0 1.2556 TRIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88835 ZNF155 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07716 PGPEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48326 GSE130620_1_v_0_kdm4b_human RummaGEO Gene Perturbation Signatures 1.0 null TARS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38344 TMEM11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61246 GSE164874_5_v_13_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null bone marrow HPA Tissue Protein Expression Profiles -1.0 -0.748185 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles 1.0 1.23465 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.861582 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 1.49858 Duckembryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.702 PMC12789432-41467_2025_66251_MOESM4_ESM.csv--SOX2_tumorigenesis_signature_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null PCDHB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49937 hsa-miR-3160-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 OTUB1 Pathway Commons Protein-Protein Interactions 1.0 null substantia innominata/basal nucleus, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58661 GSE239844_1_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE132369,GSE132371_5_v_0_cccp_human RummaGEO Drug Perturbation Signatures -1.0 null FARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43595 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28321 abnormal skeletal muscle size MPO Gene-Phenotype Associations 1.0 null DUSP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14805 HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -1.6467 Disease Progression HuGE Navigator Gene-Phenotype Associations 1.0 null