association	dataset	threshold value	standardized value
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69932
NCAPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33995
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.2869
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19465
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03418
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42661
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22223
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.82461
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35698
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
GSE252988_0_v_1_lefamulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49437
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0102
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3082
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845032
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51715
5808_NRBF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.716056
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62777
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87941
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92967
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60063
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839246
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408498
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-0.940995
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.543
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42239
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202106
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0522
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8272_SON_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.666329
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19488
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306069
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20163
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01121
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6044
Ubiquitin activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.584
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63123
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31526
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870078
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974493
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4422
RLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64972
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.44743
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20904
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910053
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Microtome section	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3718
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
NCIH2228	CCLE Cell Line Gene CNV Profiles	1.0	3.27899
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968521
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27146
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996055
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41042
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353096
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81457
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2372
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827472
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08566
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26871
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28658
MYC-18940864-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47433
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35619
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412799
ADAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44317
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7396
OC316	CCLE Cell Line Gene CNV Profiles	1.0	1.52757
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81204
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78191
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29997
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12089
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08921
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60561
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86526
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18636
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.50171
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927016
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17821
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73174
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42252
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16145
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19164
6096_PAX9_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.514614
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08935
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01718
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46479
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03985
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05036
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62247
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05022
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36574
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00253
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854472
CEND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14428
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02352
MYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2606
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28537
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43304
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33055
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03863
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13447
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62606
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08643
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
OXSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29494
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.803534
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	2.08798
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08155
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1238
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46705
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09207
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20904
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78072
hsa-miR-4708-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
2907_FAM216A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.691367
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4864
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11875
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14544
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230882
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43316
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68526
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99266
RNA N6-methyladenosine methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852854
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29716
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10291
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47281
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.753
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94414
DD-74-PJ26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254923
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71257
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12441
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03856
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8435
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40837
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00143
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64735
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81244
GSE188382_2_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6252
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1685
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40378
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65555
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7717
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29394
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5513
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00531
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.0119
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12149
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00843
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.899769
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25077
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219769
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354525
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTNNB1	ChEA Transcription Factor Targets	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0365
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.69284
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9506
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80433
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4124
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860288
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8681
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58667
JURL-MK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58869
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858739
Bardet-Biedl syndrome 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877953
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19432
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39067
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11039
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25589
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38077
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05872
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6744
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54628
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888385
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
RBM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
S0-EE-Y737_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24207
GSE163282_12_v_5_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7143
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6755
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50192
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49711
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17928
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07276
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925023
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2549
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96576
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41382
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880208
USP34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90361
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12563
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7253
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77183
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916757
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35034
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42145
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20534
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11634
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43933
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32171
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45342
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90457
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.661528
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11681
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73924
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5624
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95266
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QMRM-1126-SM-447BN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40951
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948483
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858739
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
within	GeneRIF Biological Term Annotations	1.0	null
PHF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92983
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.894
chr7_75501925_T_C_b38	GTEx eQTL 2025	1.0	2.16452
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67047
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908644
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41458
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26534
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48646
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0905
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04796
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952647
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.321
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00157
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4584
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.60961
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36574
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0682
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04504
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09368
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835604
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40977
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987443
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61598
MAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05461
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44969
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51409
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16572
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21485
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61428
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871127
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0668
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44948
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0522
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01216
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8404
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852103
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49561
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10558
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48666
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09799
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4569
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926422
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40095
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25904
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39708
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22823
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931203
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02017
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84137
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51796
Zinc finger, C3HC4 RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69394
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16791
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.2523
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219958
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17868
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45007
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53594
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.651805
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14162
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963945
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10488
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37284
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6412
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29209
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976951
cation binding	GO Molecular Function Annotations 2015	1.0	null
BXPC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870496
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60123
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6023
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99144
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97042
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31956
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31991
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.05166
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.301
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71569
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05916
RBM22_02_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.14296
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58908
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17845
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.10938
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94861
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10601
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22293
1943_CTR9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.760626
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39113
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84057
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62144
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380574
NPIPB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81265
8670_TAF8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.655069
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901776
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02191
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.652
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79801
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.006
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873749
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979607
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44568
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85554
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900932
CTNNB1-20615089-FETAL_BRAIN-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63518
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Supravalvular aortic stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48068
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0661
NOMO1	CCLE Cell Line Gene CNV Profiles	1.0	2.59887
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08233
SYNCRIP_OE_GDS4596_85_human_SW480	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81579
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57605
USF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984877
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02219
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35015
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60949
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.04544
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05758
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863892
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64181
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02219
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26068
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48702
MED29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14503
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21305
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41535
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.12954
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98537
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.21728
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.994992
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959104
PMC10290283-biol-2022-0622-sm3.pdf-20-NEUROD4_NEUROD4	Rummagene Transcription Factor Associations 2026	1.0	null
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25832
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32858
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62608
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24067
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857412
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54732
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24747
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4521
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91508
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.39318
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02225
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891175
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22883
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975229
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64461
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10518
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.19525
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72085
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.652
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06979
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93637
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19206
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60055
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73296
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2999
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13955
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65239
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01449
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20346
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79267
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844893
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	3.05877
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72483
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2047
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02442
YBX3_02_98	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59851
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227855
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32344
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68709
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932982
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27617
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03743
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24908
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845911
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34516
GTEX-XLM4-0226-SM-4AT4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837823
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07304
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50315
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51198
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.14807
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22001
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220259
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399582
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898069
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38266
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03238
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0522
BRD4_01_119	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54182
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10763
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38221
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974941
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6691
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84804
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934029
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0827
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0661
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30663
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07796
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7701
fat_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02896
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9088
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.52276
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29058
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12966
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846684
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38742
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64256
U343	CCLE Cell Line Gene CNV Profiles	1.0	1.34473
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90377
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17163
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92702
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38035
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977672
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3961
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40586
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.70583
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01406
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.59769
AB-96-XV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20118
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.87482
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75669
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69891
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408597
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5178
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94011
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62494
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15138
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66778
AHSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22147
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00867
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963325
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
YBX3_02_153	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.07121
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12089
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937539
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71742
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37152
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24541
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13531
AF-10-QK79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202921
EXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.73662
PMC11148097-41698_2024_569_MOESM2_ESM.pdf-213-ZNF277_ZNF277	Rummagene Transcription Factor Associations 2026	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13158
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927016
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06342
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76821
C32	CCLE Cell Line Gene CNV Profiles	1.0	1.45748
INKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84452
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29099
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
NCIH1339	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44544
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9487
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80609
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13202
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10532
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92899
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853174
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.35472
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44391
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96629
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-2.67653
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885429
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52925
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35926
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.75093
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16157
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911414
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921767
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953849
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929565
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2398
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84775
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.58652
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48358
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22293
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46686
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OC314	CCLE Cell Line Gene CNV Profiles	1.0	1.45521
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
MYC-18940864-HL60-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28174
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09943
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6647
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22265
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75418
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60875
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11768
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16413
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81423
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21787
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32859
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26986
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57438
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
hsa-miR-609	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	1.0	1.30473
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49792
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47019
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53163
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10693
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04685
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_13_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956551
REL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50275
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95195
stomach	HPA Tissue Gene Expression Profiles	1.0	1.79773
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08706
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7121
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09695
HTR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7229
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89885
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78598
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24889
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72747
18713946-TableS3	GeneSigDB Published Gene Signatures	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45592
CYBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64775
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892528
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53244
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502087
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2497
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76865
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
1560_CHD4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52396
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26763
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85104
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00317
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
6860_PSMC3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.650184
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84584
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.23163
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14279
LSM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63862
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
PMC7137223__F2	PFOCR Pathway Figure Associations 2024	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11209
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31598
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06164
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07479
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33715
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898417
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16193
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74728
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3588
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65324
623 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.812
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939411
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40503
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05217
OGDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.757
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12441
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04999
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4111
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23913
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227969
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60218
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-0.89758
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48278
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57371
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61748
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05976
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
HMGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8046
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39511
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984537
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324519
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.824453
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0826-SM-4DM5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3471
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30711
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3514
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35761
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64733
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88451
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
syndrome	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88547
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40878
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893908
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291006
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951075
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832675
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56003
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6536
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45698
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863157
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926735
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07279
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58673
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35287
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61262
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858684
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45762
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37167
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845032
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04044
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
HEYA8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48252
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50477
stomach	GTEx Tissue Gene Expression Profiles	1.0	1.91996
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.78466
MF-11-EW49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215997
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7084
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23854
region	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86659
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6786
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	1.0	3.20837
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76531
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
BFTC909	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46096
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29495
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51569
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30771
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
hsa-miR-3137	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PMC12335956-BNEO_NEO-2024-000529-mmc1.xlsx-4_chr7essentials_published-THP1_Wang_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.80388
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83457
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907059
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28951
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.08876
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48996
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855153
JPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02358
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1786
ALAS2_OE_GDS2118_74_human_Blood	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02979
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35976
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18126
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46435
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60983
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25841
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45798
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46166
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87374
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65264
GTEX-S4UY-1626-SM-4AD55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8703
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88579
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15211
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6632
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50525
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92703
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.06181
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39242
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23038
DD-43-WW40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255236
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78087
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33333
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845998
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92993
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41699
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13849
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42932
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1692
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29502
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.521455
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90435
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0536
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65927
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48202
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5506
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83112
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17273
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48181
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930009
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05602
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22079
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96851
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97979
znf263_19887448_helas3_lof_human_gpl6884_gse19146	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.843415
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888727
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31859
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19880498-TableS6	GeneSigDB Published Gene Signatures	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84378
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94904
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64447
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871163
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9767
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.125
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19311
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-2.36036
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29083
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873749
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5557_NDUFB5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.606601
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06382
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68409
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75635
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67382
TBRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47612
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28949
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886623
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54187
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9169
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927016
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.632452
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63479
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23586
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
dg3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39234
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11415
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29233
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275418
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46264
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5741
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4277
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3793
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32716
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14463
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09273
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1233
ncih1650	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22763
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64374
HCC2279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90222
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44407
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23221
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879866
rectum	HPA Tissue Gene Expression Profiles	-1.0	-1.46547
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15207
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865811
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95444
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0661
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87282
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58352
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_REPRESSED-RING1B_EWSR1-FLI1_repressed_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845479
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11471
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76544
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880128
PINX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46738
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49722
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13391
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56073
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51969
dg1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46329
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28247
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38461
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77375
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
PMC3348545-NIHMS263168-supplement-3.pdf-208-MLXIPL_MLXIPL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06352
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72612
ACAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846061
maps	GeneRIF Biological Term Annotations	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55408
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840118
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16704
ED-00-OH22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255145
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48709
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.76454
hsa-miR-4735-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81265
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3243
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6063960-41598_2018_29472_MOESM5_ESM.xlsx-lightcyan_module_HF-DMRTB1_DMRTB1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Split hand-foot malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.54975
NHLF	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.01992
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51257
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.59608
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925384
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20849
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04037
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37966
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29397
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868465
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
DROSHA_02_145	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60942
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954565
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
ADGRG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79734
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95316
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31934
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9128
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100617_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13785
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06481
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29935
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46442
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10433
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48074
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	1.0	4.31679
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64339
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91358
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847379
dg2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27326
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912743
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07177
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05703
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.911492
RHOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3872
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.892285
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976951
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.125
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04992
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59331
6794_PRPF38A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512625
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18108
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37183
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03869
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.25609
GSE147626_2_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.125
PMC12055596-41375_2025_2570_MOESM4_ESM.xlsx-PDX1-Unnamed_14_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926591
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0661
ion binding	GO Molecular Function Annotations 2015	1.0	null
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
GTEX-OXRK-1626-SM-3NB17	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17232
NALM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70444
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406396
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94969
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77867
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09993
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63513
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45273
GSE182680,GSE182683_0_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23822
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51218
Williams Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4731
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19927
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61833
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26409
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58747
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8625
mRNA editing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25657
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37084
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.66642
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79213
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48529
MATN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07547
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68075
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60802
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25175
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04747
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29764
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4416
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1882
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18869
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13866
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362321
RAB23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30757
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08567
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957664
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887442
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58091
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22401
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50944
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88884
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16376
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27779
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66803
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62787
POU2F2	ENCODE Transcription Factor Targets	1.0	null
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02483
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56617
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01685
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28658
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58203
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44544
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53637
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18491
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5697
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05232
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA46	CCLE Cell Line Gene CNV Profiles	1.0	1.94179
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19492
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14277
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30605
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.867456
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1448
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20144
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02441
PMC7137223__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0844
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4966
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77132
9751_VPS35_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.708381
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1765
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64438
LN382	CCLE Cell Line Gene CNV Profiles	1.0	1.3881
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42166
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38258
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205391
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926108
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857747
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7974
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52765
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51519
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3638
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90596
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24706
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09087
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.48417
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37844
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06724
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2716
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29521
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
pc3	HPA Cell Line Gene Expression Profiles	1.0	1.12863
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870396
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74822
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.582344
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26163
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30612
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293748
PMC7137223__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.69523
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-2.73819
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244344
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925384
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10052
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66371
EFM19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53972
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988543
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48335
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.995842
8833_TFAP2A_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503445
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50677
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6389
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01205
P3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67034
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00439
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990978
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.565
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9358
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
binding	GO Molecular Function Annotations 2015	1.0	null
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04232
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57941
MYC	ChEA Transcription Factor Targets	1.0	null
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86452
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02231
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977672
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63032
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.75197
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55946
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05372
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836394
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28511
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26818
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25936
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6818
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53005
6611_PPAT_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.518632
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995794
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9545
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944617
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50243
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	2.10014
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4381
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999105
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31474
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304184
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.588294
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24366
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3697
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92955
NMCG1	CCLE Cell Line Gene CNV Profiles	1.0	1.44741
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70434
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29042
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8955
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06561
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.866262
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85687
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32712
4150_INTS5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.548077
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.48485
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81515
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94151
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63174
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.203
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970253
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.06211
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53395
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30253
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.901776
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39851
BLTP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89614
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34926
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38291
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498102
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
hsa-miR-4787-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23611
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41828
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89682
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03052
CCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56081
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22237
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940557
FOSL2	ENCODE Transcription Factor Targets	1.0	null
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93747
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.771008
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13176
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91978
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74973
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74174
GE-77-FY84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238377
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858507
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97664
8772_TCERG1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522431
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39759
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48905
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20345
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989478
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.72841
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.636985
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.198
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70031
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23666
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36574
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60769
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74323
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40971
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07116
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991418
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08356
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00027
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49361
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29869
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871266
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30422
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16156
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18497
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0277
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
7178_RBM48_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.603917
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90205
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36175
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203453
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74397
GSTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70107
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36486
FTC133	CCLE Cell Line Gene CNV Profiles	1.0	1.71431
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.29576
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22997
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90966
hsa-miR-3674	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66044
williamsbeuren	GeneRIF Biological Term Annotations	1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52542
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05916
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845238
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986548
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81472
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02886
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81719
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944457
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90108
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
957_C11ORF74_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.753086
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32884
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70863
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0795
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47499
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976997
HC-76-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240008
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZFPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23708
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36642
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.71349
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84631
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2447
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18775
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8197
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858774
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71062
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.5365
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937426
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10648
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925384
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42041
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929013
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976951
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24269
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05872
106_ACTL6A_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.16122
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44602
1812_COX19_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.618077
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2472
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zinc finger, B-box	InterPro Predicted Protein Domain Annotations	1.0	null
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85124
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64537
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34608
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80589
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76024
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68814
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888648
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973454
PMC7825356-8844261.f3.docx-70-ZNF736_ZNF736	Rummagene Transcription Factor Associations 2026	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.055
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23047
NCI-H1650 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45031
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42291
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22887
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07294
Mulibrey nanism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.49739
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59489
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834041
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980659
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17957
hsa-miR-3164	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28951
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05276
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37313
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951631
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0446
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986272
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51535
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17982
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09642
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.363
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873749
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
SNU520	CCLE Cell Line Gene CNV Profiles	1.0	1.34987
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.41154
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48016
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00735
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827618
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918601
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.710099
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08945
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19464
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0661
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
hsa-miR-483-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966247
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78549
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48331
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24659
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-O5YW-3026-SM-3MJHI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856587
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36627
ZC3H12D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64459
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr7_75428063_A_G_b38	GTEx eQTL 2025	1.0	1.35985
rectum_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10334
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5746
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89918
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99556
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36343
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17821
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882352
PMC7137223__F3	PFOCR Pathway Figure Associations 2023	1.0	null
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.39791
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.79164
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0402
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.559
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12962
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42823
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01453
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01154
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80843
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09234
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2013
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878709
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28835
TRIM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32417
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45158
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.652
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21403
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.856845
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07684
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428
critical	GeneRIF Biological Term Annotations	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874668
STAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31086
RPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73186
GSE185519_4_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Zinc finger, RING-type, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20545
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26457
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84727
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968065
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85692
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88307
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.43508
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.49781
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48749
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30376
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23411
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34233
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50473
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04013
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2837
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00819
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05019
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319026
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79943
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26668
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43257
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39518
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.652
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58592
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927016
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965858
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967334
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.509
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
ERR2 (ESRRB)	MotifMap Predicted Transcription Factor Targets	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7611
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14694
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45933
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2365
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48674
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01482
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15865
496100435_TCx_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01588
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08899
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27886
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24641
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27299
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72817
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969339
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.942
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8438
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855696
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38611
IMPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23154
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858739
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.71219
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61147
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290828
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982575
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49838
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20674
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953681
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36837
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04044
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	1.72051
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.791384
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68043
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13422
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04622
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4136
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75387
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27886
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-0.97803
IRF1	ChEA Transcription Factor Targets	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482489
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885932
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911588
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96382
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QLQ7-0826-SM-447B3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09256
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6013
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95078
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84696
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901204
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58102
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26909
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212301
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.04678
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33711
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955569
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20904
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76278
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381557
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998673
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69097
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3857
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46485
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.60724
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06599
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26478
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49413
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.125
YAP_OE_GDS3220_32_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89921
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15308
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22567
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7834_SF3A3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.627031
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.49618
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977672
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03484
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82647
SNU5	CCLE Cell Line Gene CNV Profiles	1.0	1.48654
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63529
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32671
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09255
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21367
intracellular	GO Cellular Component Annotations 2015	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17957
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868229
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9011
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05289
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11193
PMC6961462-NIHMS1544104-supplement-Sup_Tab.xlsx-Sup_Table_3_a-Supplementary_Table_3_Genes_Regulated_by_A_MYB_in_Humans_and_Macaques_Bold_genes_with_reduced_expression_in_Group_3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
chr7_75506399_A_G_b38	GTEx eQTL 2025	1.0	1.50714
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2599
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944712
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02506
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27776
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676942
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02969
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11853
SLC52A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29208
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82872
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22588