association	dataset	threshold value	standardized value
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2576
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3875
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1	Rummagene Transcription Factor Associations 2026	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3888
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3121
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.349
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75458
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3389
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0906
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39549
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45285
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8734
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4398
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2434
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
GSE147366_3_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
ETV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25027
SYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66835
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1452
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8518
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.585
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
GSE198165,GSE198166_8_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2391
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6256
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2223
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84741
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6275
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45082
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.433
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5071
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
Mitotic checkpoint complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.354
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4291
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
GSE224237_1_v_2_resiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5664
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1616
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68067
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0095
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4862
PROCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16111
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRRC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43409
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3333
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13478
GSE211286_7_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54334
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7379
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.46521
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69078
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93967
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07939
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	1.0	null
UGCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82489
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1775
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91596
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3755
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2347
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33838
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7618
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27677
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4491
MFSD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66015
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1094
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7235
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0126
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1066
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36946
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0889
PKNOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01818
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.895
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60822
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5076
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50391
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83054
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior horn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8176
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27057
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11445
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83087
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.33218
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5747
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_7_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.14589
GSE206270_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8509
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8894
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6626
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88491
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6228
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4675
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6841
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.773
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5489
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cargo receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.235
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24906
GSE161827_1_v_3_ertugliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ubiquitin conjugating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.645
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78994
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3095
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
female meiotic nuclear division	GO Biological Process Annotations 2025	1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68771
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
GSE149426_1_v_0_cygb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4903
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5651
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62561
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
NME6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90787
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01361
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.45
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
PLPPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02208
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
GSE184133,GSE184137_1_v_9_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43993
female meiosis I	GO Biological Process Annotations 2025	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82627
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
PRKRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47547
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
GSE159206_1_v_3_drd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2875
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02323
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06791
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4165
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2384
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42956
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9198
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40112
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4259
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26266
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
meiosis I	GO Biological Process Annotations 2025	1.0	null
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5225
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2693
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58688
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71965
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43049
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47498
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70065
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9999
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00652
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43939
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18353
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3226
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32856
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6763
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7742
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.79354
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20345
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2188
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76017
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
ZNF296	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59604
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.454
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89867
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9282
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0278
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1872