association	dataset	threshold value	standardized value
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.18
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18368
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
fluoxetine_danio rerio_gpl1319_gse31712	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68540120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50536
tinea pedis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.61083
HCC1195	CCLE Cell Line Gene CNV Profiles	1.0	1.387
Schizophrenia_CNS - Brain - Cerebellum (MMHCC)_GSE4036	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48391
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31507
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
HT1080	BioGPS Cell Line Gene Expression Profiles	1.0	1.05061
snps	GeneRIF Biological Term Annotations	1.0	null
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13166
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45404
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20869
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	0.839974
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23462
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171142
COLO-668	GDSC Cell Line Gene Expression Profiles	1.0	2.70128
CRCGN011_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1395
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.29609
PACADD161	DepMap CRISPR Gene Dependency	1.0	2.09369
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
TE10	DepMap CRISPR Gene Dependency	1.0	2.74307
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.22924
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71563254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18797
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13879
K562_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015419
C4II	DepMap CRISPR Gene Dependency	1.0	2.70162
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50799
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42619
7515_RPS26_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.771343
BRD-K12175788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94196
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39966
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15411
BRD-K75100119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85782
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
PATU8988S	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23022
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08695
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K24035524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56069
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.26409
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr1_39879939_G_A_b38	GTEx eQTL 2025	1.0	1.33545
NCI-H1836	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.16838
JHH7	DepMap CRISPR Gene Dependency	1.0	2.26656
BRD-K63299476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45434
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13117
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09549
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
Isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.65929
BRD-K75426080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27743
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89719
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LC-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3738137-bjc2013359x6.pdf-3-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32145037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48198
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00971
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71671
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10919
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10542
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10878
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Transcription factor TFIIIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16324
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39116
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298165
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00603
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51572
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.603316
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
endometrium	HPA Tissue Gene Expression Profiles	1.0	1.1228
one	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16975
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0664
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.21855
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68474
K562_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173491
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.68841
TRIM	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6657
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stomach Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
NFKB1_01_167	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.29186
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79869
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01519
K562_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0302387
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843855
BRD-K60716223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6069
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33907
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	2.06905
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.15
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80875
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955194
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00104
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98176
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13726
BRD-K05977380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31694
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18352
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.02388
BRD-K64347765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1041
K562_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0111097
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14133
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19356
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-0.991148
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16664
HT	DepMap CRISPR Gene Dependency	1.0	3.2036
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1963	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78177
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K70127757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92261
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33402
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919235
NCI-H378	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053951
JIMT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95265
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.972465
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31167
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26865
Lip And Oral Cavity Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54392
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29968
A549_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144767
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24851
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
additional	GeneRIF Biological Term Annotations	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6852
(S)-Crizotinib_LOX-IMVI	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00892187
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97606
Acid phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
Receptacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2805-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32938
monomethylarsonous acid	CTD Gene-Chemical Interactions	1.0	null
MELAS syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847544
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35846
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.956576
hsa-miR-4519	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC11892598-pnas.2417308122.sd05.xlsx-DEGs_of_RORC_cluster-Unnamed_3_RORC	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29407
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_DEPLETION_GDS2445_117_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HDQP1_BREAST	CCLE Cell Line Proteomics	1.0	2.15612
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.613635
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4394
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06335
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17576
MCF7_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129577
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84822
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C3A	GDSC Cell Line Gene Expression Profiles	-1.0	-2.10767
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13902
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28277
7566_RRP7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553178
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38895
Protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51448234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89521
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00104
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80827
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68544484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6535
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.842429
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01332
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914103
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.181107
SIRT6	ENCODE Transcription Factor Targets	1.0	null
Immune Thrombocytopenic Purpura	DisGeNET Gene-Disease Associations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33192
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12826
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.913044
BRD-K03849840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20839
Macrophage_Spleen_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3034
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
K562_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159086
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852738
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4491	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TCF12	ENCODE Transcription Factor Targets	1.0	null
PMC11059513-mmc1.xlsx-Supplementary_Table1-Table_S1_The_gene_profile_was_down-regulated_after_HIF1A_was_knocked_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
9299_TRIT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.63599
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Combined oxidative phosphorylation deficiency 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.09
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048262
Lung transplant rejection_Lung Tissue_GSE2018	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79005
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853011
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45409
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13607
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13902
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0725
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.248
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10875
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.18945
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43876
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MFM223	DepMap CRISPR Gene Dependency	1.0	2.20742
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74767736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01904
trit1	GeneRIF Biological Term Annotations	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91648
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rovs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03825
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04092
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61704
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.929655
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223392
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trna dimethylallyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75748
H3K36me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908699
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15134
mitochondrial tRNA processing	GO Biological Process Annotations 2023	1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS273	CCLE Cell Line Gene Expression Profiles	1.0	1.821
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43122
Benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29898
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Charcot-Marie-Tooth disease type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Bacterial biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
BRD-K95264594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15168
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210411
HS839T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89888
allele	GeneRIF Biological Term Annotations	1.0	null
Spinalcord	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09417
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.48937
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01749
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	0.902116
nuc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.74538
histamine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52697
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88831197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05441
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992273
subjects	GeneRIF Biological Term Annotations	1.0	null
K562_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240009
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85949
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186397
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38113
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18285
Sideroblastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83889
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72772
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947568
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98627
CHD2	ENCODE Transcription Factor Targets	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34963
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68584
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8621
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882969
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42509
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01556
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11063
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89976
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15749
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.34314
BRD-K03562091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25979
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4012
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12065
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46324
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89865
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938592
Esotropia	DisGeNET Gene-Disease Associations	1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.931042
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01562
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UNC-1999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13334
K562_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156268
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1470	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Prostomium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37784
PD-94-WO47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233576
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0297
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.81307
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.55536
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	2.93001
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SP4	ENCODE Transcription Factor Targets	1.0	null
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.896
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0245952
HCFC1	ENCODE Transcription Factor Targets	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861928
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.22322
BRD-K70039231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35321
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.278
hsa-miR-4722-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876603
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874352
NCI-H520	GDSC Cell Line Gene Expression Profiles	1.0	1.50854
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08039
7312_RIOK2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.532166
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01107
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2146
BRD-K46413323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42529
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46789
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502942
CRCGN008_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9227
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23571
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935117
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7971
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59266
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bc89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Proplastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.55973
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47018
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271445
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95895516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51606
Leaf axil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88827
BRD-K16746805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58882
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846064
BRD-K41887762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24298
Peroxisomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GATA2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62369
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916063
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4925
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991723
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48358
6493_PNO1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.549524
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41198
EOMES	ChEA Transcription Factor Targets	1.0	null
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8917
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36551
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2447
Myoclonic Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.833441
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26617
Endopeptidase Clp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29502
fh50	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
P31FUJ	DepMap CRISPR Gene Dependency	1.0	2.8797
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21726
Hereditary spastic paraplegia 55	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18632
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04142
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09475
BRD-K36282114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28792
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32999
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974007
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24919
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71173
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25974714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19238
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21752
K562_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187687
BRD-K14124956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19581
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LYSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60567
BT12	DepMap CRISPR Gene Dependency	1.0	3.20586
Actinic keratosis_Skin tissue_GSE2503	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52611
BRD-K75076471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44839
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971419
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05278
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61103
K562_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173127
2622_EMG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64064
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SREBF1	ENCODE Transcription Factor Targets	1.0	null
Root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.041
K562_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158377
BRD-K42605555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48887
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3186
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
DC-49-EJ23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440185
molecular_function	GO Molecular Function Annotations 2015	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
A375SKINCJ2	DepMap CRISPR Gene Dependency	1.0	3.09763
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051642
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75395
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36882679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07632
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-40-POU3F1_POU3F1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13958
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14373
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.141
alar plate of p1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00133
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76166595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96077
Glutamate synthase complex (NADPH)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03945
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79602
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1694	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.27715
DBH_KO_GSE33906_53_mouse_heart (E10.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K40646662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28929
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18307373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9996
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53988
Pyrophosphate	HMDB Metabolites of Enzymes	1.0	null
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.648
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0944
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836644
Alzheimer's Disease_CNS - Brain - Hippocampus (MMHCC)_GSE1297	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.47081
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73851
Seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.138
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29928
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167619
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17222
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
7522_RPS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525444
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42172
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25702
Plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19085288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74591
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15177
BRD-K83527041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24373
BRD-K98953346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35155
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AM966	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19835
huH-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.7205
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51562
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.852284
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932314
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28371
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.54
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63209730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23111
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2122
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09968
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.522
Prostate adenocarcinoma_PRAD_TCGA-XJ-A83F-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2321_DNTTIP2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507358
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70876639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16181
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3885
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2318
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7866
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83342
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36793
SJSA-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.61782
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.25499
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06505
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.03345
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Apical bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6371
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14719962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46784
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Transient infantile liver failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
K562_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151692
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10534
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75206417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35359
7561_RRP12_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.589426
UPCISCC026	DepMap CRISPR Gene Dependency	1.0	2.21634
NB10	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.70436
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76502
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70755
BRD-K60578515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01774
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16019
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
LNCAPCLONEFGC	DepMap CRISPR Gene Dependency	1.0	3.04992
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965485
FGF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07268
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41037
Mitochondrial tricarboxylic acid cycle enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03437
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042009
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.928275
Major Depression, Single Episode	DisGeNET Gene-Disease Associations	1.0	null
BRD-K30917841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26909
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2029	CCLE Cell Line Gene CNV Profiles	1.0	1.62038
Combined oxidative phosphorylation deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
tRNA modification in the nucleus and cytosol	Reactome Pathways 2024	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69834831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29418
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07595
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22762
BRD-K26924781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29273
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Glasdegib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0228041
TYK2_knockdown_35_GDS4754	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69841
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01105
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8206
7508_RPS19BP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.629731
NCIH520	CCLE Cell Line Gene CNV Profiles	1.0	1.52772
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.9253
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39567
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29915
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48412518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25445
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18907
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6363
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAP4K5_knockdown_199_GSE61497	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.58166
NRF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3180-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Scrapie	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2679
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0352
BRD-K66214118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15608
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10378
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96677
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57167256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63153
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88121
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211593
IKBKE_knockdown_97_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.45916
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918703
EOL1	DepMap CRISPR Gene Dependency	1.0	2.71281
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55465
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57620855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34675
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38299
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196671
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H747	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7466
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41191
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91137832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45722
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_9_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49765
RNA modification	GO Biological Process Annotations 2025	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
rhombomere 8	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37664
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.748798
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.35177
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.321
SNU-175	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.89611
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25243
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHOC5	DepMap CRISPR Gene Dependency	1.0	2.12731
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17061
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989353
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
2988_FBL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.620875
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.61919
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17120673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1667
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00464
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
BRD-K29475348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05677
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44797534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42114
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.473
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8137
BRD-K06772291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27589
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.846831
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50413
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.45304
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05636
Overexertion_Leukocyte_GSE3606	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.36677
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
BRD-K65266979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70828
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65414
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31404
Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13101
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61853
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87602457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23371
Liver Diseases	CTD Gene-Disease Associations	1.0	1.12117
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13958
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36237864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66762
FA-88-II68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216611
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.13558
BRD-K52582315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74249
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02475
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00631971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.416
HIPK2_overexpression_28_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.37119
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5689001-supp_061432.117_Supplemental_Table_1.xlsx-A_Seq_KD_cassette_exons-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06328
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56542
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21979
ATF3	ENCODE Transcription Factor Targets	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.845327
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
BRD-K64626569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13312
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40499
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44927
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32185
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53639
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19568
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.55958
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43428
K562_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170283
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3768
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.30763
BRD-K67150949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86497
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
precommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11214
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844979
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9675
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37002
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87162
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3976
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
non-small cell lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204263
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94831
SETDB1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840609
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17084
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.877836
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03989
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897601
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18632
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045185
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K67278762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34959
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02848
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85724
Pharyngeal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCI-H2029	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.07631
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04835
A549_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161476
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.55008
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897284
PK1	DepMap CRISPR Gene Dependency	1.0	3.11854
pb92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20639
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cyclin/CDK positive transcription elongation factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.154988
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35451051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60533
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A2-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
MON1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00615868
Phloem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
CHD1	ENCODE Transcription Factor Targets	1.0	null
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26068
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
K562_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250271
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25858
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24089
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71544970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25219
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826789
Pemetrexed_RPMI-7951	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00915174
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912614
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904394
NCI-H748	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.02996
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.15998
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948294
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999269
Kco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
snp	GeneRIF Biological Term Annotations	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31549
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10579
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U937	DepMap CRISPR Gene Dependency	1.0	2.12255
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS-273	GDSC Cell Line Gene Expression Profiles	1.0	2.05431
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873874
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
1083_NEPRO_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.580721
T47D	DepMap CRISPR Gene Dependency	1.0	3.14642
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85493
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42918
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07758
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20379
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A25687296_EMETINE_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11501
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9465090__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419821
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0241
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13958
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tube foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.064
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19774
BRD-K40265664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11599
EKVX	CCLE Cell Line Gene CNV Profiles	1.0	1.35595
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836944
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.04553
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40652
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876603
Interfascicular region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
Anemia	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970107
NCIH2110_LUNG	CCLE Cell Line Proteomics	1.0	6.4177
BRD-K72894736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44997
BRD-K67750179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7311
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00104
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.29609
BRD-K03067624_EMETINE HYDROCHLORIDE_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17293
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.64578
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913174
HMV-II cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.85558
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907966
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962079
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33218
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19584
BRD-K21206585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19023
BRD-K60719499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18379
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH1703	DepMap CRISPR Gene Dependency	1.0	2.81576
Transcription factor TFIIIC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02396
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85228
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26140483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24185
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
BRD-K68732617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02441
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.814
K562_PCI-34051_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184045
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99608
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	2.64277
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5413
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.567186
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
Bursa copulatrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
7513_RPS24_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.514568
RERFLCAI	DepMap CRISPR Gene Dependency	1.0	2.38306
U031	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.41826
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08907
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45841
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08683
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55859
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52798
Perturb_3467_KO_Tie2_SRP325056	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.7358
PMC11003700-pbio.3002240.s018.xlsx-GOBP_NCRNA_PROCESSING-Unnamed_1_ATOH7	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.09366
CEBPB	ENCODE Transcription Factor Targets	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64349
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12479
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876603
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93728
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055015
Photosystem II oxygen evolving complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
NCIH2172	DepMap CRISPR Gene Dependency	1.0	2.87077
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.193394
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123943_4_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF7L	ChEA Transcription Factor Targets	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3319
HEC50B	DepMap CRISPR Gene Dependency	1.0	2.07362
7561_RRP12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.643817
496100594_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03545
BRD-K10564128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19141
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91758
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36127
K562_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0238265
HCoV-EMC2012_0Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.17896
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0733
BRD-K44126416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04252
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
RCHACV_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.76902
inferior frontal gyrus, opercular part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.85205
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20901
E2F1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1666_LUNG	CCLE Cell Line Proteomics	1.0	2.73382
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
BRD-K77108448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28081
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20156
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05423
carboxy-terminal domain protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
Epileptic Encephalopathy	DisGeNET Gene-Disease Associations	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5113
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0659
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03573
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Secondary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03797
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990635
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14774
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tRNA threonylcarbamoyladenosine metabolic process	GO Biological Process Annotations 2023	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03516
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80762
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30767
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.32192
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
SARS-dORF6_12Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.985116
hsa-miR-622	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60468
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06202
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09968
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.431302
BRD-K65663356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48858
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14829
tRNA modification in the mitochondrion	Reactome Pathways 2024	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74897
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08438
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06883
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60872
PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71352
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19149
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54779
BRD-K63102090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20553
GSE216538_7_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.80096
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947595
JURKAT	BioGPS Cell Line Gene Expression Profiles	1.0	1.36249
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	1.86505
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0205
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7269
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041347
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV JFH1_120Hour-Huh7_5_1_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26598
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	ChEA Transcription Factor Targets	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90923
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.70842
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52188
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle lumen	GO Cellular Component Annotations 2023	1.0	null
frequencies	GeneRIF Biological Term Annotations	1.0	null
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17969
BRD-K29238078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3882
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49485
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02049
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23464
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18002
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tRNA dimethylallyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K73051782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13164
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08881
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31330911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40777
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNZTA3WT4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.10973
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916192
Inflorescence primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02051
BRD-K23867157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03527
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6987
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.21791
7525_RPS3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.634365
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33682
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09095
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18641
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.1
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0244927
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60688
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09018
HUH7	DepMap CRISPR Gene Dependency	1.0	2.92629
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857459
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22017
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.71308
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931432
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15645
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01387
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46618
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12273
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5719
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.861675
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior adductor muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00238
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19215
JHH1	DepMap CRISPR Gene Dependency	1.0	2.79583
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34426
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0047
node	GeneRIF Biological Term Annotations	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31641
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0228
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32674
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26478
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47134
K562_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175321
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
9600_UPF1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.86073
Hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.131
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97191
Scape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957889
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.15865
BRD-K77787814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65254
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81994
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059677
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2171	GDSC Cell Line Gene Expression Profiles	1.0	1.44412
Mitochondrial DNA depletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
Bulbil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890744
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
ZNF263	ENCODE Transcription Factor Targets	1.0	null
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03675
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44517
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80088
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93459372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07224
LM3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
Ulcerative Colitis_Peripheral blood mononuclear cell_GSE3365	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49385
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55787
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.19704
allelic	GeneRIF Biological Term Annotations	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42677
K562_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0248661
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.791
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1853
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21476
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.932169
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2886
K562_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0206672
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.21919
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.944372
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00566460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22738
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.091
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28895
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial DNA depletion syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0397
BRD-K68298468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81842
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4703
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47183
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82029
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69559
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.4767
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06694
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47913
K562_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146055
NCI-H250	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19717
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07895
NCI-H196	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.49102
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01283
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29994
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846401
Dystonia	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972678
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25756
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06381
LS-180	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.7814
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02172
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
DMS-273	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.94657
GSE49929,GSE49931_1_v_0_irf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67084
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86884344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22122
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05123
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18404
Perturb_11322_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.15348
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0625
MCF7_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00752591
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP66-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.75679
Glycine reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905137
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08343
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35407
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV434	DepMap CRISPR Gene Dependency	1.0	2.20429
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85794
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3484
Perturb_17653_KD_DNMT3A_SRP367237	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.64132
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35613
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2823
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63678
breast cancer	GAD Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152537
TRIM33_knockdown_304_GSE32903	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.62358
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15785753-Table2	GeneSigDB Published Gene Signatures	1.0	null
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28837
BRD-K73952959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38698
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79945
hsa-miR-4477b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DF-00-BX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385512
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052726
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930388
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.49909
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.16688
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ES4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.67803
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37496
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26816
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30719
9210_TPP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.52372
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22839
TCF3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8796
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01736
SNU5	DepMap CRISPR Gene Dependency	1.0	3.0833
BRD-K25993054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9532
BRD-K74641261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15599
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36813
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13884
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.48487
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53807
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70773
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
THAP1	ENCODE Transcription Factor Targets	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.46621
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B	ChEA Transcription Factor Targets	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52999
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_G007-LK_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145332
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.843
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13385
K562_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176899
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42537
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509992
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8583
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28007
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221723
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22242
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906744
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88996
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
virion part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072845
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0428
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09644
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63584
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14774
TT1TKB	DepMap CRISPR Gene Dependency	1.0	2.66673
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250853
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39731
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11997
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07423
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63303
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38522
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061158
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057478
USF2	ENCODE Transcription Factor Targets	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31167
NR2F2	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23854
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.969863
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11111
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91156
PMC11530610-mmc3.xlsx-WGCNA-ZNF697_ZNF697	Rummagene Transcription Factor Associations 2026	1.0	null
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94917
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
catalytic activity, acting on a tRNA	GO Molecular Function Annotations 2023	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.23083
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SB-94-ZA83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297212
K562_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016987
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85788
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ADF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
tRNA dimethylallyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19757
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26963
cation binding	GO Molecular Function Annotations 2015	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.893462
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68807
BRD-K95577144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00296
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45683404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21697
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
BRD-K28813194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01612
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2122
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.00339
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02056
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23255
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838094
ZFP42	ChEA Transcription Factor Targets	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12743
K562_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284009
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7862
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06425
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKMEL30_SKIN	CCLE Cell Line Proteomics	1.0	2.65713
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7297_KO_CD34_SRP156691	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.25291
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46649
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Variable Expressivity	DisGeNET Gene-Phenotype Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4519
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Thylakoid light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10308
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917436
BRD-K60521891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13679
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08166
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13789
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.242595
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1092	GDSC Cell Line Gene Expression Profiles	1.0	1.57581
HA-99-PM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317973
Stolon tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.414
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19568
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ethnic	GeneRIF Biological Term Annotations	1.0	null
Enteroendocrine precursor cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29812
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14485
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A8BP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67604
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29798
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29292
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03113
risedronate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1132
Cerebral Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.669668
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17253
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47757
Myopia	DisGeNET Gene-Disease Associations	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19568
EFM192A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58367
Digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
PMC10153265-media-3.xlsx-BENPORATH_SOX2_TARGETS_v2023_1-STANDARD_NAME_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91783
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43467
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29753
Lung squamous cell carcinoma_LUSC_TCGA-60-2711-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2676
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958921
A498	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.82276
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18849
OVK18	DepMap CRISPR Gene Dependency	1.0	2.50894
Plant gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.877
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytochrome b6f complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43936610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53432
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13877
BRD-K41498330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60064
ATF3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03426
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06304
8166_SMG5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.806087
Necrosis	CTD Gene-Disease Associations	1.0	1.90342
Brain Lower Grade Glioma_LGG_TCGA-R8-A6YH-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345928
Pontocerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
okt3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
GSE218060_2_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13793
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96575
K562_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0264869
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41265
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3112
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6204
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980003
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58244
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.15776
Exodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
Walking leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K66432757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22117
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09985
HC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K05339908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63769
SUDHL1	DepMap CRISPR Gene Dependency	1.0	2.94376
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03166
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33524
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.78431
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15021
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921444
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233303
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Shoot base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
MITF	ChEA Transcription Factor Targets	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12002
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923268
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K33873762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35911
3774_HIST1H3H_ENST00000369163.2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.54051
Tinea pedis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
BRD-K61691014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30729
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57026098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31544
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21209
Corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24796
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14675_KO_RpL13a_SRP090469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.8102
True leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a549	HPA Cell Line Gene Expression Profiles	-1.0	-0.828511
KOPN-8	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.66085
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28691459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34756
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043152
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909254
hsa-miR-1299	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.382
4472_KRR1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.565081
BRD-K75534737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34356
Arsenic	CTD Gene-Chemical Interactions	1.0	null
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07857
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2223
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6522
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESO51	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.79889
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40944
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73259
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.913379
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31278
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051268
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64784
BT-549	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.7328
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.752078
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057335
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26181
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35101
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13724
K562_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230813
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.826
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25251
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.51905
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17098
BRD-K88924787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60884
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086709
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72286
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40745976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02519
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239916
Zinc finger, double-stranded RNA binding	InterPro Predicted Protein Domain Annotations	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
8227_SNRPC_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.587895
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32403948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20896
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220803
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14228
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2889
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07504
three	GeneRIF Biological Term Annotations	1.0	null
Perturb_13006_KO_C3_SRP235282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.39387
Sieve plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16052
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27246
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02398
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00593
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09049
BRD-K02529187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12347
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
BRD-K09432998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13465
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157454
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11511
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.829231
7943_SKIV2L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515446
K562_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217776
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10852
BRD-K63024248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2223
A549_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144702
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.900542
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65831955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68741
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Disulfiram_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162178
HPAF-II	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46154
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918801
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87988
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03554
nuclear	GeneRIF Biological Term Annotations	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25699
ES7	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.98449
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07184
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900475
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938251
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23843
2124_DDX47_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553536
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82143
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.92758
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00728
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23544
MDA-MB-361	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70213
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900627
BRD-K67638302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1371
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.35792
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4519
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial DNA depletion syndrome 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Biotinidase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12033
tRNA (m2G10) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03292
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209379
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88215
Elytron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851635
K562_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173363
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990988
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.67972
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.04976
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80856
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12216
PPAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72225
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K32506050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27455
Perturb_16475_KO_Irf6_SRP173803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213048_1_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ray floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883461
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67844
Silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049547
Lymphatic Metastasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.12887
BRD-K72800151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00005
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7634
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05177
BRD-K93726930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24474
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tRNA modification	GO Biological Process Annotations 2025	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07276
Axillary bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.355
BIN67	DepMap CRISPR Gene Dependency	1.0	2.23016
mitochondrial matrix	GO Cellular Component Annotations 2025	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49956
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14666
NCI-H524 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
Cytoplasmic exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.16203
BRD-K38097136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63774
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.53246
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	1.55342
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
showed	GeneRIF Biological Term Annotations	1.0	null
BRD-K06876397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50776
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	GDSC Cell Line Gene Expression Profiles	1.0	1.71203
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052135
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05596
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07817
Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.846214
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42544
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-GSEA_TET1-Unnamed_4_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42782
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15687
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A2780	DepMap CRISPR Gene Dependency	1.0	2.21095
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GOTO	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5012
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.0
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35339
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.978618
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01285
PMC9886955-41420_2023_1325_MOESM12_ESM.xlsx-H6_14AvsH6_NC-Unnamed_2_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24343201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49331
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.246
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19891
Weight Loss	CTD Gene-Disease Associations	1.0	1.33464
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24388
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896662
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08952
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Akinetic mutism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
A549_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00871746
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.912277
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874059
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239007
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31443
Darolutamide_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0176679
Vascular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876976
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9679_UTP11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.550377
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tRNA methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.958
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K29331543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09658
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01074
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.65333
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890317
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854506
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21888
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00554
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90641
BRD-K99387963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39005
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26614
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47704
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
DMS-273	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054836
ncrna metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925393
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54801
FLI1	ChEA Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982818
Combined oxidative phosphorylation deficiency 26	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7558
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889539
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840609
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.13963
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H378	GDSC Cell Line Gene Expression Profiles	1.0	2.84787
K562_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014657
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854849
BRD-K71420819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60775
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47514
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03501
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23487
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
BRD-K06431647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43702
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171673
NCIH1437	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75991
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74777
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10589
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04142
Stipule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28628
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04369
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13879
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22442
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09832
Storage root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32723
ChIP_MYC_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
K562_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216905
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21291
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19572
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
approximately	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11954
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized Myoclonic Seizures	DisGeNET Gene-Disease Associations	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04841
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hif1a_16565084_mcf7_lof_human_gpl2507_gds2761	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.271349
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.01286
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01285
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA modification	GO Biological Process Annotations 2023	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911694
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08974
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16274
Primary leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52589
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JAR	DepMap CRISPR Gene Dependency	1.0	3.12711
K562_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162239
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.32011
Mitochondrial intermembrane space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944506
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.36311
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18923
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917742
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24558
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.86311
Taproot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97627
SAS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
Muscular Dystrophy_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE3252	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.63094
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.18415
8166_SMG5_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.18394
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16564
CL-11	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.7475
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844857
BRD-K70050144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91455
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Frond	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50629
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890027
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19886
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32643
HS819T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82679
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58693
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4164-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2105_DDX18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.577884
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K91022335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70226
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884382
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.97361
liver	HPA Tissue Protein Expression Profiles	1.0	0.756866
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fh100	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
HCC-33	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02637
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21961
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.964036
NCI-N417 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.711
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04758
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208137
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56086
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Goldenhar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857855
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01195
Perturb_5532_KO_Hur_SRP174218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.0705
Perturb_9500_KI_Trp53_SRP201382	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.96784
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13879
BRD-K68084083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5589
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.911
BRD-K62718031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04248
BRD-K49999779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21557
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZR751	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63966
Monopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202027
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08735
BRD-K81501934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8566
LC-1F	GDSC Cell Line Gene Expression Profiles	-1.0	-2.2975
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56071
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.568
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16019
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14275
hsa-miR-1283	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51405
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16967
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42315
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994773
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91062
CRCGN015_HEPG2_48H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15385
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390696
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01469
Pretectal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55059
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51945
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989551
POU2F2	ENCODE Transcription Factor Targets	1.0	null
3-Methylcrotonyl-CoA carboxylase 1 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39381
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73994
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40806
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49178
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26127722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18409
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12634
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00304
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162436
chr1_39841226_T_C_b38	GTEx eQTL 2025	1.0	3.69115
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46338
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00212
JHU-022	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.17558
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874599
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
more	GeneRIF Biological Term Annotations	1.0	null
BRD-K07409609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32749
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70049
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
BF-89-QD24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22712
BRD-K85572169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0094
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03568
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35688
BRD-K88662980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42176
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93763
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85428
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22139
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968745
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23074
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.909601
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65963
TEN	DepMap CRISPR Gene Dependency	1.0	2.95349
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C8-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30084
Microsporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8661
control	GeneRIF Biological Term Annotations	1.0	null
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
NCI-H1876	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18596
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28197
LB771HNC	DepMap CRISPR Gene Dependency	1.0	2.37803
8166_SMG5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506836
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172544
BRD-K83300227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24171
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25767
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72347
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
7526_RPS4X_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.613797
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04089
9443_TWISTNB_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604435
cutaneous mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.20785
USF1	ENCODE Transcription Factor Targets	1.0	null
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
5888_NUP155_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.501968
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9318
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924239
HCC-33	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.40987
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870813
BRD-K23208879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18799
BRD-K46458719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48075
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.39128
K562_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164492
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Depression	DisGeNET Gene-Phenotype Associations	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.666321
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59748
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.57641
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51907
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K67725403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81047
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pantothenic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30938
Exosome (RNase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26228
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1232
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9542
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98604
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.404042
SNU638	DepMap CRISPR Gene Dependency	1.0	2.44671
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830736
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
HCC33	CCLE Cell Line Gene CNV Profiles	1.0	2.60675
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-175-VII	GDSC Cell Line Gene Expression Profiles	-1.0	-1.9213
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.21028
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30697
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06455
Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE5370	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.06327
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04492
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49026
PMC12439337-thnov15p9091s1.pdf-110-ENSG00000172845_SP3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19584
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72127
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28039328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50801
143B	DepMap CRISPR Gene Dependency	1.0	2.73905
BNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46578
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052438
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61338
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
Interfascicular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28828
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53608
Partial motor epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073414
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
Mesocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32908
HC-16-VX59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287645
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16021
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338378
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.898
Nuclear stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924793
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18802
AZACITIDINE	DGIdb Drug Targets 2026	1.0	2.6466
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.29609
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.87139
metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893448
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I8-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bacterial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46341
condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274835
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15636
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38275
hsa-miR-3074-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34493
DMS153	CCLE Cell Line Gene CNV Profiles	1.0	1.46299
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855159
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885059
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044026
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
DMS273	CCLE Cell Line Gene CNV Profiles	1.0	1.98155
BRD-K36515664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27679
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846982
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Carcinoma, Non-Small-Cell Lung	HuGE Navigator Gene-Phenotype Associations	1.0	null
Otopalatodigital syndrome spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26163290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20481
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2492
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03469
TC-66-CI47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352966
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01376
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2577
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35011
22RV1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.15859
AGS	DepMap CRISPR Gene Dependency	1.0	2.67251
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K64091938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48086
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882145
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.8015
BRD-K52124788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0462
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951045
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93532
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382966
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.30737
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5580_NECAB3_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.648462
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54204
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24781
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19989
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70502
BRD-K97362312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13279
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25707
GATA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1955
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
Typhus Group Rickettsial Disease	DisGeNET Gene-Disease Associations	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1647
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48697
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15311
GTEX-U3ZN-1226-SM-4DXUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05108
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71809
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12169
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19454
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03869
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SHMAC4	DepMap CRISPR Gene Dependency	1.0	2.05521
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110708_0_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163762
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946252
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.53841
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.78988
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
propranolol-5358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.263
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8218_SNRNP27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.555581
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leigh disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44415
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983127
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.017
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840898
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848816
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06323
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.59168
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959775
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3077
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239916
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915072
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K50140257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01188
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01685
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55145
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.249
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32761
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.50313
mitochondrial tRNA modification	GO Biological Process Annotations 2025	1.0	null
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917269
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20304
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63965
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20437
BRD-K74109014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20299
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00328
NCI-H446	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.76215
FOXM1	ENCODE Transcription Factor Targets	1.0	null
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.388
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60731
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914028
Plasma membrane proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988455
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42697646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9529
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60379
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43983
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13879
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
embryonic lethality prior to organogenesis	IMPC Knockout Mouse Phenotypes	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02618
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BFTC-905	GDSC Cell Line Gene Expression Profiles	1.0	1.65829
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.563864
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17061
DBH_KO_GDS4324_362_mouse_Embryonic heart  E10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
embryonic lethality prior to organogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9302
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
JM1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.03739
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48115
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880482
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875344
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64083
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44433
Brain Lower Grade Glioma_LGG_TCGA-DB-A75L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3965
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37493
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STK33	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pitcher	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54123736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44259
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22481
Mlg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00059
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01462
WM1799	DepMap CRISPR Gene Dependency	1.0	2.85402
BRD-K41310621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21594
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15612
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
6992_QTRT1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.601002
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95185
7164_RBM22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.670861
Multiple carboxylase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GB-19-AP57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233686
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66105
Scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
BRD-K36055864_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Cormel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8666_TAF5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.507522
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34188
KYSE70	DepMap CRISPR Gene Dependency	1.0	2.5166
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06212
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40778
SK-MEL-24	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14972
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63051
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18399
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.002
BRD-K87472370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25335
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67948
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05525
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967342
BRD-K99034771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05394
Amyloplast envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046566
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75912
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	2.33721
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.098
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17197
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862647
K562_UNC0631_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226933
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.03885
differences	GeneRIF Biological Term Annotations	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
K562_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182606
Phellogen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
BRD-K56661847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46129
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80635
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10589
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4895-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948078
NCIH2291_LUNG	CCLE Cell Line Proteomics	1.0	2.6567
K562_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158359
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22962
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20312
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32274
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79709959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27481
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36892
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050841
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7364
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40931
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847742
tRNA threonylcarbamoyladenosine metabolic process	GO Biological Process Annotations 2025	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.747185
KDM4A	ENCODE Transcription Factor Targets	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.63282
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5371
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI2650	DepMap CRISPR Gene Dependency	1.0	2.12517
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.922025
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.264
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04915
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07759
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36711
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22084
1083_NEPRO_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.541221
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46271
BRD-K90741031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74662
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23989
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18931
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_14_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13455
TCCSUP	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4493
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EW-18	GDSC Cell Line Gene Expression Profiles	1.0	1.44845
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44517
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02385
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19584
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.121
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Large Head (Disorder)	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969485
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24366
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cloned cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16004
K562_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156939
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54495
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00609
AS-30D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962289
PACADD137	DepMap CRISPR Gene Dependency	1.0	3.16846
C2BBe1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67923
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30167
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2829
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841953
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244727
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24686
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05468
BRD-K31683335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61153
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8247
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29089
A172	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51111
BRD-K56650430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.86376
Infantile hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
BRD-K44445002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38841
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.087
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KNS81_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	3.42501
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91516
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47387
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983839
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.983306
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29507
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.985888
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91399333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02832
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.383
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34401
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
RNA polymerase I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
KYSE180	DepMap CRISPR Gene Dependency	1.0	2.12309
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894044
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171439
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_6_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.37528
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90512
K562_Tozasertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015762
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40386
SNUC4	DepMap CRISPR Gene Dependency	1.0	2.95425
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997436
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16699
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862893
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52798
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9175
BRD-K35693854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12615
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09511
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248852
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Malignant Transformation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12054
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14112
WSUNHL	DepMap CRISPR Gene Dependency	1.0	3.15218
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38583
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04275703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2379
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869746
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0951
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
BRD-K73376409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11117
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.59231
K562_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158034
NCI-H1092	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
COLO741_SKIN	CCLE Cell Line Proteomics	1.0	2.17779
Plant crown	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	1.42269
HEK 293T	BioGPS Cell Line Gene Expression Profiles	1.0	0.845078
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984962
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.47845
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.314
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN443	DepMap CRISPR Gene Dependency	1.0	3.20074
BRD-K71839680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0341
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20495487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45878
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
CORL24	CCLE Cell Line Gene CNV Profiles	1.0	1.58478
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71173
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K73296134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57128
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35931
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.165172
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00291
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56446
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960006
7527_RPS5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.615343
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE33_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.69037
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29643
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Rucaparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160166
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08247
BRD-K21866464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07567
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.674354
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3615	MiRTarBase microRNA Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABC1_LUNG	CCLE Cell Line Proteomics	1.0	2.1728
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_SRT3025 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154356
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.977272
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.874678
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03266
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.195
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.097
biological_process	GO Biological Process Annotations 2015	1.0	null
BRD-K33939287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13558
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24076
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K50191826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52667
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21689
SRF	ENCODE Transcription Factor Targets	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42172
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53551
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0044
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13414
ZFP42-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64835
SKNAS	DepMap CRISPR Gene Dependency	1.0	2.07668
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02472
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17209
K562_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159139
MPNST724	DepMap CRISPR Gene Dependency	1.0	2.69413
20368555-TS-1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13407
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921523
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.12872
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
NCI-H1694	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961515
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2159
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70211
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934506
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936423
7507_RPS18_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504493
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.73711
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876603
mitochondrial RNA modification	GO Biological Process Annotations 2023	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60069390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11902
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.29609
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26582
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04694
8738_TBL3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.564426
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71608
PMC12784616-12711_2025_1028_MOESM2_ESM.xlsx-TableS8-Table_S8_Summary_of_significant_MR_associations_in_liver_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9389
NB17	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52351
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17166
TT2609C02	DepMap CRISPR Gene Dependency	1.0	2.26817
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55605
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21407
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34748
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24643
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05419
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63409
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32833
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49553
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73025859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32895
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02336
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853651
BRD-K75551005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69019
BRD-K72646819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1811
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
Protonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
discuss	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0533
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52974
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69819
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80227
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39772
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896068
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93009
NFIC	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2273
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS944T	DepMap CRISPR Gene Dependency	1.0	3.14004
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	0.895818
DU-145	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.84512
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6147
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873666
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05143
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19584
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832528
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.31
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Metabolism of RNA	Reactome Pathways 2024	1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22623
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016561
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80213
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62369
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72108
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.12
COLO679_SKIN	CCLE Cell Line Proteomics	1.0	2.59793
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29455
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32766
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.23981
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10545
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06776
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65859
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37728
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43195
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240664
K562_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189553
Perturb_16482_KO_Irf6_SRP173804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.5263
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22044
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	0.82627
Osteoarthritis_Chondrocyte_GSE16464	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49782
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02471
BRD-K54107674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26503
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13705
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68618340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44983
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54586
BRD-K69942587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12696
GSE185519_6_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12135
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4536
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
6493_PNO1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.60358
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987229
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55538
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
COLO-792	GDSC Cell Line Gene Expression Profiles	-1.0	-2.67208
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50358
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11215
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5745
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60069
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.495029
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855293
K562_RG108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182632
PMC11227377-2506586.f2.pdf-8-ARID5A_ARID5A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Curli	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845623
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04049
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00998
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23085
20min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Root vascular cylinder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
some	GeneRIF Biological Term Annotations	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40426
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.74317
BRD-K61877191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54507
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52859
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261331
ncrna processing	GO Biological Process Annotations 2015	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79161
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955326
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0243
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02093
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876275
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.899
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04523
11906190-Table1b-1	GeneSigDB Published Gene Signatures	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041651
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16104
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881098
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.12
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2034
K562_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152183
NCI-H2029	GDSC Cell Line Gene Expression Profiles	1.0	2.10951
Adenocarcinoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tuberous root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887977
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
TE11	DepMap CRISPR Gene Dependency	1.0	2.10882
WD-62-UB45_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205527
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21545
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24913
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Appendicitis_Appendix_GSE9579	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.54868
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37154
Epileptic encephalopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Apical hook	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0948
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10266
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07674
9687_UTP6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526395
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.72838
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1706
BRD-K31526203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02396
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54227
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21781
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenoma_Colon_GSE4183	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.35848
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.245
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78549
BRD-K79665135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08846
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.07788
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22681
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1763
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181823
COLO201	DepMap CRISPR Gene Dependency	1.0	3.18192
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41106
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15831
Hydathode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825289
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2796_EXOSC9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.590351
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25122
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62577
RPS17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597641
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.43834
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.313718
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02885
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08222
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
t99-vena-cava_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.65908
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872194
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053578
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23497
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07105
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02353
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05551
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13346
CRCGN015_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0921
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23618
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69381
BRD-K36709933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13216
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2172_LUNG	CCLE Cell Line Proteomics	1.0	3.56902
BRD-K31898235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80257
7957_SLC12A4_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.570729
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4103
Shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.313
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10557
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73462
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39118
BRD-K58070604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50467
BRD-K17065706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26864
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83784
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02665
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79604175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60592
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2335
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00045
NCIH510	DepMap CRISPR Gene Dependency	1.0	3.2008
BRD-K56590597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1713
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03568
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872578
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36487
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CC-84-JQ48_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233786
SNB75	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.61503
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.44289
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19495
K562_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170152
A549_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160055
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23964
BRD-K92457070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72767
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.886
Hypanthium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
Ascites tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954324
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052659
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9314667-Table_1.xlsx-Regulons-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
TRPM7_defectivemutant_306_GSE23102	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.62889
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.519553
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.876558
K562_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017248
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4072
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171286
BRD-K23316636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36396
K562_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0362057
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.07364
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.665804
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15612
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11687
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31238
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89835
K562_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239232
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938841
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0694
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222693
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.47329
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46562
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040736
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57459
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928755
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
MYC_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90004
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068616
cytochrome-c oxidase deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3244
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77716
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349012
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16262
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
specific	GeneRIF Biological Term Annotations	1.0	null
KD	DepMap CRISPR Gene Dependency	1.0	3.05317
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_363_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13406
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13958
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00133
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33748896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37118
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41374
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74628
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lm8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46338
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902051
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.545
K562_BMS-754807_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239557
BRD-K67491390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2142
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5982
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1274
BRD-K54533560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7695
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.021
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Callus	DisGeNET Gene-Disease Associations	1.0	null
respiratory chain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131731
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K28785305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09186
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.88658
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.41639
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37299
Perturb_12948_KD_FIS1_SRP144742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91154
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2886
tRNA processing	Reactome Pathways 2024	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251057
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.995
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8125
Hereditary sensory neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Depression	DisGeNET Gene-Disease Associations	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947568
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249919
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37977
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72829
Prostate adenocarcinoma_PRAD_TCGA-HI-7171-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Condition, Preneoplastic	DisGeNET Gene-Disease Associations	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33163
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33472
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28082
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01824
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19198
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7925
Exodeoxyribonuclease V complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2671
lymph	GeneRIF Biological Term Annotations	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876603
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3608
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03932
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.625685
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.309235
K562_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169159
Perturb_735_KD_PAF1_SRP048744	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83737
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	1.92993
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.54806
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.964
NCI-H510A	GDSC Cell Line Gene Expression Profiles	1.0	2.28084
BCLAF1_02_112	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60058
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
BRD-K97733472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36478
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN008_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02705
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28707
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28462
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80065
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829825
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947904
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
Labellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21038
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21904
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970163
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61183
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49419779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18993
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37195
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61799
BRD-K21582416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04924
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.81312
Mitochondrial ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97732
dms273	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17796
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.191135
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82988
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67113
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18966
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52416366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27925
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.835165
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43017
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16476_KD_Ripk4_SRP173803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.43901
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11927
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haplotype	GeneRIF Biological Term Annotations	1.0	null
Leaf vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10936
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16838
Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74196
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H1963	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.3922
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43011
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2141	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
K562_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175018
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152432_9_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88820027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84603
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9565
Frontometaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
trna processing	GO Biological Process Annotations 2015	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6988
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55612
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49091
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19403
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0022
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15767
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BFTC-905	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.23078
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
trna metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04448
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46055
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3387
Familial Dilated Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
viral membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188905
THP1	CCLE Cell Line Gene Expression Profiles	1.0	1.45357
BRD-K96154586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15835
GSE149035_7_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.22478
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.66734
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.40586
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
8109_SLC7A6OS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.622529
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTDK-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.684
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.00676
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850594
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23844
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.39226
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08419
Chronic progressive external ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_ST-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84782
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6397
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051117
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94657
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kuru	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8120022-CTM2-11-e420-s006.xlsx-Sheet1-Table_S1_786_altered_genes_involved_in_cancer-related_pathway_in_TMPRSS2_ERG_fusion-positive_prostate_cancer_Genes_involed_in_multiple_pathways_are_duplicated_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.21422
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Proteinuria	CTD Gene-Disease Associations	1.0	1.12634
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43763
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.802558
PMC9314667-Table_1.xlsx-Regulons-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.90835
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64266251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34023
BRD-K75703503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15438
Stem cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
Whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.378
Autosomal recessive Robinow syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
5462_NAPA_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.804474
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941343
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867641
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61W-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15858
OVCAR3	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08156
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926705
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
K562_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197681
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-2526-SM-48TYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826155
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.56381
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0911
Phosphoric acid	HMDB Metabolites of Enzymes	1.0	null
2105_DDX18_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.28105
Combined Oxidative Phosphorylation Deficiency	DisGeNET Gene-Disease Associations	1.0	null
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901289
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04061
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61697
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14081
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37254228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17053
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K83270266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02073
BRD-K13672060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00793
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24913
atp binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K55465787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14667
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim29_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31144
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24261
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Early myoclonic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.159
LN229	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69592
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48946
BRD-K21423945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24213
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0372
viral envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.205399
6575_POP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.519933
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.25588
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATOIII	DepMap CRISPR Gene Dependency	1.0	2.62081
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.467
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20924
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.878
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62369
SMAD4	ChEA Transcription Factor Targets	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655953
golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77557
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7537_RPS7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.59381
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3119
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.526101
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7582
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945157
SK-N-AS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
m86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5643
A549_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152128
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90693
BRD-K67390061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57739
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881568
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996523
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37477
GTEX-TMMY-1926-SM-4DXUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913388
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143344
BRD-K60918542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75243
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981891
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial matrix	GO Cellular Component Annotations 2023	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00438
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31728
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88699
tRNA-intron endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861996
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868359
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152866
BRD-K10317744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45257
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K88278778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40395
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.71
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50423
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_up_VENN-442_common_elements_in_HIF1_peaks_and_HIF1_genes_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994735
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8446
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05915
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29753
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866774
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952958
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13681
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90548911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15944
Streptococcal tonsillitis_Tonsillar Lymphoid Tissue_GSE11494	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.8995
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988393
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91205
BRD-K22418614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45867
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11249
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02917
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999872
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09608
tRNA dimethylallyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1505
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K73177528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28948
0min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01757
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05132
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051331
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7330_KO_CD34_SRP156691	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.14235
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.19537
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894516
BRD-K74289419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58175
BRD-A64237946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04878
CCND1	ChEA Transcription Factor Targets	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05219
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19525
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.541
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
proteinreview	GeneRIF Biological Term Annotations	1.0	null
PMC12486367-Supplementary_Data2.pdf-80-ZNF250_ZNF250	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62014
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46305
GTF2B	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29272
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.08584
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2179
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
POU5F1	ChEA Transcription Factor Targets	1.0	null
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K55562948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68658
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40381
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
BRD-K68395284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04439
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088987
mantle zone of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13804
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19403
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04638
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30943140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10718
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.76
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tRNA processing	GO Biological Process Annotations 2023	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90899
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04977
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73052
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05272
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920045
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16604405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66921
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61525
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270664
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1969
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4762-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47488
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23560817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01835
Fostamatinib (disodium hexahydrate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.021099
TE-441-T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.99668
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36093
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
cellular process	GO Biological Process Annotations 2015	1.0	null
IPC298	DepMap CRISPR Gene Dependency	1.0	2.49816
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
K562_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161026
Leukemia_promyelocytic-HL-60	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.83175
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317447
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCLP1	DepMap CRISPR Gene Dependency	1.0	2.85989
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1909
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUM1	DepMap CRISPR Gene Dependency	1.0	2.16313
BRD-K27864398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76447
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18404
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
BRD-K65945126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55744
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42214
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78649
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857828
ion binding	GO Molecular Function Annotations 2015	1.0	null
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.751
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.9577
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4892
larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tm903	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.092
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
metastasis	GeneRIF Biological Term Annotations	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230735
Mitochondrial degradosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50627
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4113
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95829
TNIP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459282
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58111
Root apex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
BRD-K48845054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16188
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37311
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56603
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
7312_RIOK2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.585348
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31278
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53783
3331_GDI2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.584944
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03038
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-146b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922117
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873342
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8974
10703_ZNRD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.606854
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63512
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.88451
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52383
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79738
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
10min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30693
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17166
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lisch epithelial corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1672
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35057
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236555
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33106
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23418
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2747
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57443
BRD-K40939137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25623
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2205
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Isopentenyl pyrophosphate	HMDB Metabolites of Enzymes	1.0	null
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07839
NCIH1876	CCLE Cell Line Gene Expression Profiles	1.0	1.52441
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057161
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10479
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43961
commissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13936
ETS1	ENCODE Transcription Factor Targets	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.919
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.90145
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895143
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902993
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29347
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922536
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13792
ca96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67819
Thoracic leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976373
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26122
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27441
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0968
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10743
Rabies CVS-11_7day-Spinalcord_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91587
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Absent Speech	DisGeNET Gene-Phenotype Associations	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914227
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
Etioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884405
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BE-27-RQ61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313589
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25779
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	4.69137
SH4	DepMap CRISPR Gene Dependency	1.0	2.06612
SNU245	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43084
K562_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158099
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4451
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99893
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047077
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10502
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.102
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73290515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06026
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17889
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898509
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57915
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Secretory trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871925
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17983
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.842628
K562_GSK-LSD1 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191315
1min_EGF vs ctrl_HeLa (Human) [17081983]	SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands	-1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862779
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979917
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35985
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29305
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50504
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873002
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14607
CDK3_knockdown_110_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.772
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134272
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5931
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68882
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22499
THP1	CCLE Cell Line Gene CNV Profiles	1.0	2.09415
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.973
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03426
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42336
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0705
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1364
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050533
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.854526
OSC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior adductor muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30154
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3324
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0509
catalytic activity, acting on a tRNA	GO Molecular Function Annotations 2025	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dermatophytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25297
BRD-K64663625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20985
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.48227
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07229
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220952
K562	CCLE Cell Line Gene Expression Profiles	1.0	1.35742
Sympodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
BRD-K46095779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5522
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0257008
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40191
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.53744
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dimethylallylpyrophosphate	HMDB Metabolites of Enzymes	1.0	null
Villous adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Combined oxidative phosphorylation deficiency 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08332
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07541
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060929
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8831
YD8	DepMap CRISPR Gene Dependency	1.0	2.84702
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.78649
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897013
Galloway-Mowat syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6232
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMYD3	Pathway Commons Protein-Protein Interactions	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954865
NCI-H2029	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08595
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6901
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63965
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28213
ccgt	GeneRIF Biological Term Annotations	1.0	null
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
EKC/KEOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.677
BRD-K91766181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30843
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02192
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.03084
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27172
mitochondrial respiratory chain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210894
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940343
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240941
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21215763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94623
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
Regorafenib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.021783
YMB1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.52604
OE33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40462
NCIH1792	DepMap CRISPR Gene Dependency	1.0	2.25399
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
ETV6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27376
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.87317
CUX1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tRNA modification	GO Biological Process Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4-Aminobenzohydrazide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
HaEpi cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
Quinidine (15% dihydroquinidine)_Hs 766T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00311709
ED-43-XF39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314654
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894516
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6927
caucasian	GeneRIF Biological Term Annotations	1.0	null
BRD-K46609723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26301
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.38016
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62981
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27522
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05628
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242567
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45291
BRD-K81131499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15557
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33106
5735_NOL6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.635708
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14383
BRD-K31510639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28881
BRD-K36725646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03589
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051255
MALME3M	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69426
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K57262525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03262
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883995
Granular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.52
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90307
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07905
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839387
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.920504
BRD-K64469421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32135
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	1.7756
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.237184
PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Interacting_Gene_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.42092
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12985
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46171
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052335
Secondary Malignant Neoplasm Of Colon And/Or Rectum	DisGeNET Gene-Disease Associations	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228291
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disc floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Post-Traumatic Stress Disorder	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82689
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177029
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013254
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90517
CRCGN017_MCF10A.WT.HP_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65375
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Periderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-103-SOX5_SOX5	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98525
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0343
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92344
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11846
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62022
trnas	GeneRIF Biological Term Annotations	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.777325
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898024
PSII associated light-harvesting complex II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.07376
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0017
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34316
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.161
MFE319	DepMap CRISPR Gene Dependency	1.0	2.50318
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-659	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE211151_1_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K01030150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01657
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4386
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1517
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214025
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46589
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03852
iron-sulfur cluster assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
BRD-K57786028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23983
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0008
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COR-L88	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.18791
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14977
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15586
Morris hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Mitochondrial ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.805
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3941
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09562
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04112
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887099
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.239
K562_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271155
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38416
Sarcocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07044
CHD7	ENCODE Transcription Factor Targets	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77878
CRCGN014_HEPG2_24H:L16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20565
eRF1 methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.952
BRD-K37961770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40938
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10213
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932735
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	1.38705
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2184
BRD-K33260002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23348
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06976
GATA3	ENCODE Transcription Factor Targets	1.0	null
K562_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239313
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03537
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206400_1_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81817
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07916
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H520	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
Sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829519
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.974
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.40298
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.069
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39976
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.036588
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0514
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.7121
18689800-TableS7	GeneSigDB Published Gene Signatures	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1542
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18553
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6144
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02234
Fatal familial insomnia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829846
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1713
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thp1	HPA Cell Line Gene Expression Profiles	1.0	1.53199
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.166
BRD-K38557431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51212
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31458
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87864
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66058
Perturb_16081_KO_Myf6_SRP212302	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGFOD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514194
SP1	ENCODE Transcription Factor Targets	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrial RNA modification	GO Biological Process Annotations 2025	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Microbody lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05975035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32066
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58057
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5925
Crown gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.178
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K83013052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02746
BE-69-RD44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230547
BRD-K74261250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00341
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.59
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110763
frequent	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50764
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72216066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26428
Bract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
AC-44-UR36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222713
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24268
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07158
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55725
Pharyngeal tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
CRCGN015_HEPG2_48H:G20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33577
BRD-K87340219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10443
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971528
UBTF	ENCODE Transcription Factor Targets	1.0	null
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38243
BRD-K21124684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73099
SOX2-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977168
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082832
BRD-K77354700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46005
tRNA-specific adenosine-34 deaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5905
BRD-K19245310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22911
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76081
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37134
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05325
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08106
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
Cotyledonary node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5919
BRD-K93101873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85626
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998053
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
light	GeneRIF Biological Term Annotations	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_236_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	3.14928
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial encephalomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A767-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946734
K562_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0277087
BRD-K80733946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03976
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39994
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35167
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15001
hsa-miR-183-5p	MiRTarBase microRNA Targets	1.0	null
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48178
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2545_EIF3B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.724604
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25757
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08948
hsa-miR-146a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
glutamyl-tRNA(Gln) amidotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
Spasticity, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.102
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08467
7501_RPS13_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.719844
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31212
HSC4	CCLE Cell Line Gene Expression Profiles	1.0	1.35132
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4712
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-Genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02577
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.543
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10383
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288902
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83883
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0653
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959895
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	2.23516
GOTO	GDSC Cell Line Gene Expression Profiles	1.0	1.56361
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08439
proposed	GeneRIF Biological Term Annotations	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873561
Pontocerebellar hypoplasia type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
BRD-K27178321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45458
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-1626-SM-4LVMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20627
mitochondrial tRNA modification	GO Biological Process Annotations 2023	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943412
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0708
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17451
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64098
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	1.64825
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61791241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16759
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55019
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87141723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92924
K562_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202227
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Male inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.942041
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05144
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308892
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106902
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51957
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.421
sevenfold	GeneRIF Biological Term Annotations	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.61891
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.039
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24342
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23716
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163886
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4609
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54531
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29189
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Chloroplast thylakoid membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72424071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47455
Perturb_6211_OE_FOXM1_SRP185894	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.0984
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10203
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	3.23176
SPI1-22096565-GC-B-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199049
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35273
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019693
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_SOX2_targets_Boyer_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO792	DepMap CRISPR Gene Dependency	1.0	2.287
A549	DepMap CRISPR Gene Dependency	1.0	2.04088
aminoacyl-tRNA synthetase multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06263
BRD-K56778317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0147
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
PDK1_knockout_265_GSE42187	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64847
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
imatinib_homo sapiens_gpl96_gds3046	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924239
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278038
homologue	GeneRIF Biological Term Annotations	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34595
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962412
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934456
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7719
MYC	ChEA Transcription Factor Targets	1.0	null
BRD-K04631545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46811
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.81619
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39247583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29646
NH6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08913
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13108
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34277
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65249
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15252
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26373
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40212
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28507
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63398
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P4E6	DepMap CRISPR Gene Dependency	1.0	3.10286
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7849
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.32404
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173314
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052046
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03007
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-77-ZNF441_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56413
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.544293
BRD-K28923989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44302
BRD-K44086628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90735
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06271
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13241788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08646
intracellular organelle lumen	GO Cellular Component Annotations 2025	1.0	null
MCF7_BREAST	CCLE Cell Line Proteomics	1.0	2.54957
7503_RPS15A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507025
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38097
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.83413
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01278
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7471
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Typhus	DisGeNET Gene-Disease Associations	1.0	null
RAB3A_KO_GDS2482_705_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245754
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32821
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.947563
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1836	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
K562_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018153
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30334
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4798
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01905
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06958
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880859
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52092
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.29609
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-668	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	5.46005
SAOS2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.5576
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45807
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943412
BRD-K91079447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59895
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82775
Vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
K562_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01851
rare	GeneRIF Biological Term Annotations	1.0	null
BRD-A99402294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38644
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6149
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10103
Perturb_754_OE_METTL3_SRP393226	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.28523
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95185
Organellar ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.539
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85647
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47494
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04019
mitochondrial tRNA processing	GO Biological Process Annotations 2025	1.0	null
BRD-K39961819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21777
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0939
tRNA processing	GO Biological Process Annotations 2025	1.0	null
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.854
BRD-K51253991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54693
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3186
hsa-miR-3672	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
asian	GeneRIF Biological Term Annotations	1.0	null
Compound leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
K562_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0269801
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983567
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66691
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.914675
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10014
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057392
BRD-K73261251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27364
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244475
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96789
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39168
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71109
K562_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016105
PPARG	ChEA Transcription Factor Targets	1.0	null
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS870T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45533
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-1.18917
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
Precancerous Conditions	CTD Gene-Disease Associations	1.0	2.88009
BICR22_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.61453
Immune stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37003
BRD-K74779337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09446
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956538
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
suppressor	GeneRIF Biological Term Annotations	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12899
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69805
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58786
Molting gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09449
non-syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.744
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840609
Hypertension	CTD Gene-Disease Associations	1.0	1.13518
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72106
SREBF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.198
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62401
HNF4A	ChEA Transcription Factor Targets	1.0	null
K562_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213937
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
PMC11076560-42003_2024_6230_MOESM5_ESM.pdf-77-ENSG00000197044_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5253
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_11_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66602
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
embryonic lethality between implantation and somite formation, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Crystalloid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1041	DepMap CRISPR Gene Dependency	1.0	2.148
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07584
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.193394
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27549
Wkd	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963879
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AGPAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54621
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18859
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3931
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10201
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
KMRC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72256
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08009212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36304
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833192
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08516
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7055
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK4_knockdown_225_GSE8866	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.62895
SAP30	ENCODE Transcription Factor Targets	1.0	null
COLO-668	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
K562_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220986
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental and epileptic encephalopathy 94	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67476
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0526-SM-4DM54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42756
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63829331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68942
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60359
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Stipe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.61408
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4318
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.53864
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57809
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22749
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.50044
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213487
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM14	DepMap CRISPR Gene Dependency	1.0	2.40637
BRD-K69480055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0429
BRD-K47113219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07235
NANOG	ChEA Transcription Factor Targets	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19568
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.1403
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58453
NCIH146_LUNG	CCLE Cell Line Proteomics	1.0	2.14117
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4374
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03262
Sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.25255
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27999
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pitcher secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.02568
BRD-K83755051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52994
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26850845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83235
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953619
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38931
UBE2G2	Hub Proteins Protein-Protein Interactions	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975181
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00998
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507359
fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987071
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3324-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
checkpoint clamp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.625632
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
corl88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.5628
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50566
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910215
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
K562_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018642
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34181077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42342
BRD-K53647637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17349
Mitochondrial matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
herpes simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.752085
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2668
KKU100	DepMap CRISPR Gene Dependency	1.0	2.30365
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043099
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6486
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870788
BRD-K74245698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94037
BRD-K72298899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26176
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85056
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3691
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21905
BRD-K66032509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50143
ED-71-GA72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.434654
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0353
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76276
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10723
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.82662
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35646
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.964972
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29254503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53787
Electroencephalogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901341
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2141	GDSC Cell Line Gene Expression Profiles	1.0	1.8137
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.44103
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49067
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01644
Perturb_6584_KO_Clpp_SRP114840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.73635
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38002
K562_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181534
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904117
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977961
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27968
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302866
Perisynaptic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05237
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30256
GSE123022,GSE123030_2_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
igr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.73
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03592
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98722
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06066
K562_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157199
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15211
NCI-H2171 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853111
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27208
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.46258
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
MTA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K25596713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83518
cingulate gyrus, parietal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828949
BRD-K53293966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13811
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3254
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3355
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05171
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49194
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W3-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
5738_NOL9_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.576894
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51831
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE39	DepMap CRISPR Gene Dependency	1.0	3.11782
Caulonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TYK2_knockdown_176_GSE44652	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69842
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0096
BRD-K38060656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02594
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29102
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.55656
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10218
BRD-K18523456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.5237
Internode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.93371
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.063
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54242
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
non-syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Mitochondrial disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
KMM1	DepMap CRISPR Gene Dependency	1.0	2.49102
BRD-K22039769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1954
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4775
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0035
Perturb_10356_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90017
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847599
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr1_39883661_G_A_b38	GTEx eQTL 2025	1.0	2.0531
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43782
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10811
SPI1	ChEA Transcription Factor Targets	1.0	null
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050309
NRF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
k562	HPA Cell Line Gene Expression Profiles	1.0	1.81095
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_control-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03286
K562_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271334
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55428
HDAC1	ENCODE Transcription Factor Targets	1.0	null
SKNBE2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71088
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4318
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75186244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54911
COR-L88	GDSC Cell Line Gene Expression Profiles	1.0	1.91732
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32908
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94612
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25937
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	1.0	null
THP-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03802
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.567
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31953
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350659
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1092
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.856428
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878673
GSE202587_1_v_2_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5968
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11737
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00903
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05611
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26005379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93546
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850107
NCIH684	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92571
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27129
BRD-K37831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12781
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4691-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K72255851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02719
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34718
LIVF001-012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47217
K562_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246759
IRF1	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19096012-TableS2	GeneSigDB Published Gene Signatures	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8101445-mbc-32-475-s003.xlsx-HEK_Tim22_KD-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54858
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08269
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13802
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40735
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15647573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05362
BRD-K72754669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79076
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
medullary hindbrain (medulla)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03568
BRD-K27529556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64878
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84836
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936475
BRD-K71537579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52136
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.961838
BRD-K61868194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08942
CRCGN015_MCF10A.WT.HP_24H:I22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23323
BRD-K31897694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13442
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17084
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.71018
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67698
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1233
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69456
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899737
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02746
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79541
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity, transferring alkyl or aryl (other than methyl) groups	GO Molecular Function Annotations 2015	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Combined oxidative phosphorylation deficiency 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
Phelloderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
K562_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163737
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
i-AAA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34923
NCIH1395	CCLE Cell Line Gene Expression Profiles	-1.0	-2.8471
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827445
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50603
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12321
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994586
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913357
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77684
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.19636
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0293
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01488
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50936
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36452
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00025
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
their	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30198
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849574
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79692
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHLA90	DepMap CRISPR Gene Dependency	1.0	2.06413
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37367
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.927675
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RT4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.69905
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48169
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893658
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08402
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.56238
Riley-Day syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
TRIT1 Deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5558
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC1	DepMap CRISPR Gene Dependency	1.0	3.0789
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41575
Mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
A549_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137809
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855862
BFTC905	CCLE Cell Line Gene Expression Profiles	1.0	1.64433
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.11851
BRD-K30173420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73584
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.996
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LK2_LUNG	CCLE Cell Line Proteomics	1.0	5.59727
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03845
BRD-K08504955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38552
BRD-K90863245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07856
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.99789
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23717
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RB-22-TT44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205273
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50813
HKGZCC	DepMap CRISPR Gene Dependency	1.0	3.15023
intermediate part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13804
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39090122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4698
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916454
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Floral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56041932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69446
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
16_AATF_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510139
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84922
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	2.19509
BRD-K74598339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24367
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
K562_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209306
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07391
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140352
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30883
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930832
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51447
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23085
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01503
hsa-miR-9	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K40061713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.229
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889526
KURAMOCHI_OVARY	CCLE Cell Line Proteomics	1.0	2.03891
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27466
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31148
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.49091
aztreonam-1435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.664
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879793
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17023
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0671
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45685
6887_PSMG4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.584941
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16868
TE4	DepMap CRISPR Gene Dependency	1.0	2.50638
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208827
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.16
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.8
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30662
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.14989
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.360026
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17662
Alpers-Huttenlocher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
9686_UTP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.05794
4107_IMP3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.593112
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
BRD-K11428617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04805
Combined oxidative phosphorylation deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.131
PMC8764619-mmc7.xlsx-supplementary_table_for_the_Ven-Ale_DE_MSC_genes_H_sapiens_340_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67526
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13902
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985731
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20744
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49001
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051226
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48541
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01609
BRD-K20497425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4367
BRD-K39027348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50489
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE441T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38203
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75253
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831035
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868414
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05211
BRD-K30492965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01348
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89609
Developmental Delay (Disorder)	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K76115264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1207
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.86491
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69699
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3434
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.952182
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62369
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942923
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40892
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53758
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9781
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09459
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125459
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886009
BRD-K60905390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22212
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_4day-RIPK3KO_None_GSE51526	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52422
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.627
HDAC2	ENCODE Transcription Factor Targets	1.0	null
YY1-26981420-C2C12-MOUSE-MUSCLE	ChEA Transcription Factor Targets 2022	1.0	null
Stem leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
5732_NOL10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.633905
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3628
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71173
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.337
Plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47254
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13887
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1105
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38352
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2467
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.941162
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43952
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043503
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DV90_LUNG	CCLE Cell Line Proteomics	1.0	2.23683
RBL1_KO_GDS1931_740_mouse_Neurospheres (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0054
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34604
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	2.08362
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08874
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859317
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.8788
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907345
K562_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0239479
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02542
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
BRD-K41656340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0717
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
E2F1	ChEA Transcription Factor Targets	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13255
K562_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195922
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02978
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54779
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20296
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48556518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79326
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	2.18437
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.71
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08539
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35429
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01553
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64983
NB17	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.37275
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040876
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.00983
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995215
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969131
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961611
BRD-K58412301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01743
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07021
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31279
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.09066
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3043
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57998
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.028
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Sengers syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856951
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2895
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
A549_Daphnetin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014616
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DMS53	CCLE Cell Line Gene Expression Profiles	1.0	1.35312
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03322
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CBF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
MSTO211H_PLEURA	CCLE Cell Line Proteomics	1.0	3.77588
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.149
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86665
Corm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2559
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0002
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07895
IMR32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4574
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06929
Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.29609
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
UMUC10	DepMap CRISPR Gene Dependency	1.0	2.12368
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55063
SARS-CoV_12Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99044
BRD-K92124212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14335
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29548
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096755
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.674036
NRF1	ENCODE Transcription Factor Targets	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.86339
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.34641
ESRRB	ChEA Transcription Factor Targets	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.113
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263004
hsa-miR-4284	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
free-living state	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
K562_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213066
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Root hair tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
COR-L88	COSMIC Cell Line Gene CNV Profiles	1.0	2.24139
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29408
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2146
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56127
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23275
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48422
Lung Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0981
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.33773
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6534_POLR1B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510199
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
BRD-K76154866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44865
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
NCIH1092	CCLE Cell Line Gene CNV Profiles	1.0	2.32313
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057225
BRD-K96239538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38146
BRD-K24263752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84869
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57595
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07356
GSE130246_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153777
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14658
Perturb_701_KO_TET2_SRP200817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.5591
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909528
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19235
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.44722
BRD-K01787291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25447
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32849
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13958
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41162
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841113
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89157
MAP3K1_knockout_245_GSE39240	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.16457
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25649458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10400_ZNF497_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.829962
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07458
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23069
RCHACV	DepMap CRISPR Gene Dependency	1.0	2.27242
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16868
ZNF574	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30536
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4461
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21713
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.54107
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null