association	dataset	threshold value	standardized value
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	0.67542
DG(18:2(9Z,12Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02195
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0024
DG(18:1(9Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.29518
SUSA	DepMap CRISPR Gene Dependency	1.0	2.50487
Septal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86667
DG(22:1(13Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
TMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.347967
DG(15:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6883
HCC70	Achilles Cell Line Gene Essentiality Profiles	1.0	2.91406
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6873
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39469
body composition	GAD Gene-Disease Associations	1.0	null
DG(24:1(15Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40864
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88195
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.813
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DG(14:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.82109
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20399
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04802
DG(18:1(9Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:2n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.825686
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07487
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66528
LN382	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12531
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24706
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33291
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	2.92807
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
DG(18:3n3/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051042
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04989
channel activity	GO Molecular Function Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971837
DG(20:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
Maxillary nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88221
RASGRF1	Pathway Commons Protein-Protein Interactions	1.0	null
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41678
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DG(18:1(11Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03834
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18496
MYL2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51607
DG(18:1(11Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.27355
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08602
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	2.30356
periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088685
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55639
DG(20:3(5Z,8Z,11Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19257
DG(14:1n5/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
PDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63988
DG(24:1n9/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53197
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73899
endogenous	GeneRIF Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
DG(22:4(7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.2089
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19168
DG(14:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FTC133	DepMap CRISPR Gene Dependency	1.0	3.22474
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axon guidance	Reactome Pathways 2024	1.0	null
DG(20:3(8Z,11Z,14Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.930193
DG(15:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86189
DG(24:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
697	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2597
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SAR7334	DGIdb Drug Targets 2026	1.0	2.2055
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858036
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:1(11Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
lung small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.739894
ng115401l	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
NTERA-2_CL_D1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
DG(24:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1n9/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21725
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.979
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.878666
latamoxef-3028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:2n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
PLEKHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44113
depression	GWASdb SNP-Phenotype Associations	1.0	0.394651
DG(18:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7399
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54604
DG(18:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
abnormality of cardiac morphology	GWASdb SNP-Phenotype Associations	1.0	0.67542
DG(22:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPMI-2650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873775
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88875
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23138
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHH	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44871
RASGRP4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7935918-41598_2021_84338_MOESM1_ESM.xlsx-ST12-Unnamed_0_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31889
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00252
DG(16:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884035
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64883
membrane	GO Cellular Component Annotations 2015	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.45753
DG(20:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3725
DG(14:1(9Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92103
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
DG(20:4(5Z,8Z,11Z,14Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5684
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.56525
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54487
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9178
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063457
DG(15:0/0:0/15:0)	HMDB Metabolites of Enzymes	1.0	null
TCAP	Pathway Commons Protein-Protein Interactions	1.0	null
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
DG(22:5(7Z,10Z,13Z,16Z,19Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23249
lung small cell carcinoma	GWASdb SNP-Disease Associations	1.0	0.819536
DG(20:3n9/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Muscularis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
physiological	GeneRIF Biological Term Annotations	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.914
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1034
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
DG(18:4(6Z,9Z,12Z,15Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
DG(15:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15538
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20147
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978199
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.226631
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5139
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.950052
DG(22:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518072
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07729
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27146
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47582
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.674399
GSU	DepMap CRISPR Gene Dependency	1.0	3.23652
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
alfuzosin-3203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(20:1(11Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.869084
DG(22:4(7Z,10Z,13Z,16Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03693
PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
channels	GeneRIF Biological Term Annotations	1.0	null
DG(20:2(11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39119
DG(18:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inositol 1,4,5 trisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.427254
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76364
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.762459
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43653
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DG(18:1(9Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE198054,GSE198057_0_v_1_csf1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.072635
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
DG(14:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33658
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.823
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
DG(22:5(4Z,7Z,10Z,13Z,16Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC4686785__F8	PFOCR Pathway Figure Associations 2024	1.0	null
TRMT10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84624
DG(20:1n9/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84645
zimeldine-4609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.314246
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36448
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09294
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
creb	GeneRIF Biological Term Annotations	1.0	null
neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.402318
DG(22:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
regulation of cytosolic calcium ion concentration	GO Biological Process Annotations 2025	1.0	null
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5914
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71788
MDAMB361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75652
medrysone-2544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
fundamental	GeneRIF Biological Term Annotations	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79396
DG(20:1(11Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SORBS3	Pathway Commons Protein-Protein Interactions	1.0	null
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52982
DG(20:3n9/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
RAB3A	Pathway Commons Protein-Protein Interactions	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68638
ra95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
U-CH2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular ion homeostasis	GO Biological Process Annotations 2015	1.0	null
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28682
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77418
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9416
KYM1	DepMap CRISPR Gene Dependency	1.0	2.1516
TP53INP2_OE_GDS5054_387_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.627761
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46092
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
DG(18:1n9/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
Striatonigral neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52924
PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC3-SYMBOL_ONECUT3	Rummagene Transcription Factor Associations 2026	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05665
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35244
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060521
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
A204	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Ion channel transport	Reactome Pathways 2024	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
mantle zone of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03788
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.70723
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.729797
DG(16:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060138
ELK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8175
DG(20:4n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43181
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44244
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06818
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.60091
DG(20:3n9/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47234
dysregulated	GeneRIF Biological Term Annotations	1.0	null
Ion transport domain	InterPro Predicted Protein Domain Annotations	1.0	null
DG(20:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus preopticus periventricularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
CRCGN014_HEPG2_3H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19659
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376494
DG(18:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(14:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13407
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29149
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
TIA1_KO_GSE54418_267_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TT2609C02	DepMap CRISPR Gene Dependency	1.0	2.80054
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13229
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190132
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
DG(22:4(7Z,10Z,13Z,16Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.976696
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14569
DG(20:3(8Z,11Z,14Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99065
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06889
DG(22:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
STAT3	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17768
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.33326
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
PMC11012558__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.34146
DG(20:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MYH11	Pathway Commons Protein-Protein Interactions	1.0	null
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM159PT	DepMap CRISPR Gene Dependency	1.0	2.80442
DG(24:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(15:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(5Z,8Z,11Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08817
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959306
DG(20:1n9/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6661
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.18962
DG(18:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CNGB1	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01361
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38927
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DG(24:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01355
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5896
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
DG(14:1n5/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
glioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082352
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18852
DG(14:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:1(11Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(8Z,11Z,14Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1167
plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194715
envelope	GO Cellular Component Annotations 2015	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(14:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16213
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978199
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05762
parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191555
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCI-H838 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991724
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.939503
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
DG(18:1n9/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3722
FOXP1_01_208	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60903
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8848
DG(24:1(15Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
purinergic	GeneRIF Biological Term Annotations	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096896
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42988
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922752
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8053
DG(22:4(7Z,10Z,13Z,16Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824977
TP63	ChEA Transcription Factor Targets	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769027
DG(22:1n9/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8066
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03613
A498	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90417
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06415
NFATC2	Pathway Commons Protein-Protein Interactions	1.0	null
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46175
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06451
intestinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.778986
DG(24:1n9/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
SYT1	Pathway Commons Protein-Protein Interactions	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.210945
glial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060575
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85424
RCOR1	ENCODE Transcription Factor Targets	1.0	null
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4784
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2612
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10191
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43278
intermediate stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4339
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97153
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59421
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53551
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.050696
Body Composition	dbGAP Gene-Trait Associations	1.0	0.142342
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0465
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28323
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37518
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34295
DG(20:4(5Z,8Z,11Z,14Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:1(13Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07837
DG(16:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64507
Pylorospasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5227
DG(22:4(7Z,10Z,13Z,16Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC7017417__F1	PFOCR Pathway Figure Associations 2023	1.0	null
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.286245
KMRC-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.43686
RHO	Pathway Commons Protein-Protein Interactions	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5327
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54101
DG(20:1(11Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30069
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24668
microcystin RR	CTD Gene-Chemical Interactions	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77392
Hemostasis	Reactome Pathways 2014	1.0	null
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
DG(14:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n7/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.43745
osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22158
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55145
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03733
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
focal adhesion	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
DG(16:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0843
DG(22:1(13Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SCARA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63412
DG(18:1(9Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61921
KDM4A	ENCODE Transcription Factor Targets	1.0	null
DG(14:1(9Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.471
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484376
Iris sphincter muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.568
DG(20:3(5Z,8Z,11Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412771
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05661
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9015
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61263
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48937
CALD1	Pathway Commons Protein-Protein Interactions	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884035
DG(18:2(9Z,12Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5911
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.119
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14163
DG(22:1(13Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MYL12B	Pathway Commons Protein-Protein Interactions	1.0	null
DG(16:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075135
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02213
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
DG(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.812
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87359
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62467
cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217346
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861189
DG(20:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
DG(14:1n5/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
importance	GeneRIF Biological Term Annotations	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31612
axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.231672
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.939847
DG(18:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n9/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.69045
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190566
DG(16:1n7/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.967642
DG(18:3(6Z,9Z,12Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SAT	DepMap CRISPR Gene Dependency	1.0	6.1479
DG(18:3n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.553239
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555671
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37191
DG(16:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775664
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57697
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398735
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DG(24:1(15Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70832
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
DG(20:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
COG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02656
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.58518
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068958
Nauplius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06327
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083531
DG(22:5n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.61239
SKF96365	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51074
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
DG(18:4(6Z,9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51249
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.98564
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
BTN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56037
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20185
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.558674
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9164
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
DG(20:2(11Z,14Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4153
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
DG(22:1(13Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930451
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8535
DG(18:3(6Z,9Z,12Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3n6/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.79174
transport	GO Biological Process Annotations 2015	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14063
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC3507642-1471-2164-13-355-S4.xlsx-direct_AR-activation_Cmpd30-DN-HUGO_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35936
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57267
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5936
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452198
DG(22:4(7Z,10Z,13Z,16Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.438
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80291
DG(18:1(11Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24073
DG(20:1(11Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79006
DG(20:4(5Z,8Z,11Z,14Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.46346
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(14:0/0:0/14:0)	HMDB Metabolites of Enzymes	1.0	null
Celiac ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
DG(22:2(13Z,16Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	1.0	1.38458
Alzheimer disease-presenilin pathway	PANTHER Pathways	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040728
Lung squamous cell carcinoma_LUSC_TCGA-85-6561-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
DG(18:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
macromolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.80463
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
DG(18:3(6Z,9Z,12Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07636
DG(20:1n9/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TMEM63A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31952
U-2-OS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83691
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36258
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(5Z,8Z,11Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23807
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TP63_01_199	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.18154
DG(14:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
Parabrachial nucleus, medial division, medial medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06115
calcium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
DG(18:1(11Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18296
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7222
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03479
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
protein complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38448
DG(16:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:1(13Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ML 9	CTD Gene-Chemical Interactions	1.0	null
DG(18:3n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92441
SCLC22H	DepMap CRISPR Gene Dependency	1.0	3.05856
DG(14:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38716
DG(18:1n9/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
calcium ion transport	GO Biological Process Annotations 2025	1.0	null
DG(20:1n9/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	1.0	1.5342
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5745
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCLC-97TM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OPTOBI-1	DGIdb Drug Targets 2026	1.0	3.30825
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0174
DG(20:5(5Z,8Z,11Z,14Z,17Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18569
divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
DG(20:2(11Z,14Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00484
DG(24:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.80807
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31651
pi45p2	GeneRIF Biological Term Annotations	1.0	null
DG(14:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745864
lung cancer	GWASdb SNP-Disease Associations	1.0	0.530317
Transient receptor potential channel	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84775
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34009
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14634
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33456
GSE196671_6_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(24:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42889
Ovotestis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.34857
DG(22:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85741
DG(20:4(8Z,11Z,14Z,17Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11025
DG(16:1(9Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430695
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
JUN	ENCODE Transcription Factor Targets	1.0	null
DG(22:1(13Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.694067
tanespimycin-2686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:3(6Z,9Z,12Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.21919
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.20382
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212628_2_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(18:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30392
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.984091
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2203
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(16:1(9Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50467
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.969142
DG(18:1n7/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
DG(24:1(15Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
intermediate stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34386
DG(14:1(9Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:3n9/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82643
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18725
MCAS	CCLE Cell Line Gene Expression Profiles	1.0	1.79731
DG(14:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.059755
metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17802
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2458
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5826
DG(24:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
Neostriatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
DG(24:1(15Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18775
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00165
DG(14:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40177
DG(22:2(13Z,16Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42582
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21892
DG(22:1(13Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Hemostasis	Reactome Pathways 2024	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FUCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06291
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
DG(20:2(11Z,14Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
roles	GeneRIF Biological Term Annotations	1.0	null
DG(20:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2n6/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
JHOM1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.78616
DG(22:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
TPM2	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:3(8Z,11Z,14Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRKCZ	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anion binding	GO Molecular Function Annotations 2025	1.0	null
DG(14:1(9Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00617
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.7755
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
FOS	ENCODE Transcription Factor Targets	1.0	null
DG(15:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
DG(22:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
UOK101	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.35697
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gastrointestinal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
MTHFD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69258
Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12482
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62559
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.61857
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n7/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24807
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.803
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047492
Developmental Biology	Reactome Pathways 2014	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057594
DG(24:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
DG(24:1n9/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
HSPA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06774
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36047
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03788
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signaling by GPCR	Reactome Pathways 2024	1.0	null
CAL-39	GDSC Cell Line Gene Expression Profiles	1.0	1.63925
sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700262
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08008
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.778212
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89518
DG(22:1n9/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32751
DG(20:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4479
DG(18:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95806
Tn polyagglutination syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
DG(22:2(13Z,16Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PLB985	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2584
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.50718
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
DG(22:2(13Z,16Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
DG(18:4(6Z,9Z,12Z,15Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34581
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D1-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03667
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87876
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
naringin-4605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(22:2n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4686785__F8	PFOCR Pathway Figure Associations 2023	1.0	null
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
DG(14:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
POR_KO_GDS1349_497_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
DG(20:3(8Z,11Z,14Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92875
DG(18:1n9/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6194
DG(18:2n6/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02695
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06005
hek293-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DOG	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672913
Interleukin-6 levels in non-alcoholic fatty liver disease x mastiha supplementation interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
ESR1	ChEA Transcription Factor Targets	1.0	null
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
DG(16:0e/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58818
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077349
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.37393
DG(16:1(9Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TRPC6	Pathway Commons Protein-Protein Interactions	1.0	null
DG(22:2(13Z,16Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72601
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.92638
DG(14:0/0:0/15:0)	HMDB Metabolites of Enzymes	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
trpp2	GeneRIF Biological Term Annotations	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
bronchial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6149
HCFC1	ENCODE Transcription Factor Targets	1.0	null
DG(24:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Small Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
inositol 1,4,5 trisphosphate binding	GO Molecular Function Annotations 2015	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
DG(20:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.185
MYBPC2	Pathway Commons Protein-Protein Interactions	1.0	null
bacterial-type flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.343421
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-138	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
n92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
HL60	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67356
DG(22:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
ITGB5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25864
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00168
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97664
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21379
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963658
DG(22:1(13Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
DG(14:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.3462
anion binding	GO Molecular Function Annotations 2015	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8509
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DG(18:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
carotid artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.682695
Developmental Biology	Reactome Pathways 2024	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267102
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11509
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
SK-OV-3	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OCI-LY-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:1(11Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.943075
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RASGRF2	Pathway Commons Protein-Protein Interactions	1.0	null
receptors	GeneRIF Biological Term Annotations	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.83845
PCIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69154
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1786
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18578
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56513
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056407
DG(18:2n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5626
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(14:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76487
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11243
DG(24:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
DG(15:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
MYH3	Pathway Commons Protein-Protein Interactions	1.0	null
DG(18:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.863282
DG(14:1(9Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85673
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46093
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
isthmic part of mesencephalic trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20205
DG(18:1(9Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77503
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.26955
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
osteoblasts	GeneRIF Biological Term Annotations	1.0	null
glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.781478
RASGRP1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus taeniae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
DG(22:1n9/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80302
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12199
DG(22:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
DG(14:1n5/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.064366
would	GeneRIF Biological Term Annotations	1.0	null
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00879
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.965004
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01031
arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357058
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
DG(18:1(11Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58631
median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.480091
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23285
REST	ENCODE Transcription Factor Targets	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13654
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57479
VPS26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44943
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal eye physiology	MGI Mouse Phenotype Associations 2023	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.980651
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:3n9/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46663
DG(22:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
DG(18:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
cytosolic calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2378
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62255
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04767
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229032
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59405
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6794
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.161
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01523
DG(16:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94286
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35333
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98576
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(15:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83956
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11535030-44320_2024_65_MOESM1_ESM.pdf-44-ZNF780A_ZNF780A	Rummagene Transcription Factor Associations 2026	1.0	null
DG(18:1(9Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
PMC6279925__F4	PFOCR Pathway Figure Associations 2024	1.0	null
DG(15:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Focal adhesion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.168
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2152
MPPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59246
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
TE1	DepMap CRISPR Gene Dependency	1.0	2.34088
Netrin-1 signaling	Reactome Pathways 2024	1.0	null
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48833
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIGD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5511
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161912
DG(20:3(8Z,11Z,14Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0614
DG(18:4n3/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76214
DG(16:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20867
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44497
8505C	DepMap CRISPR Gene Dependency	1.0	3.34081
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02961
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart disease	GWASdb SNP-Disease Associations	1.0	0.778061
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1317
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.21759
DG(16:1(9Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.323825
DG(14:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
IGR37	CCLE Cell Line Gene Expression Profiles	1.0	1.35504
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861588
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07184
DG(22:1(13Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62695
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40543
SKRC31	CCLE Cell Line Gene CNV Profiles	1.0	1.45013
DG(20:4n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1n9/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
SNU719	DepMap CRISPR Gene Dependency	1.0	3.9754
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71048
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833521
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10038
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3447
ITGA1	Pathway Commons Protein-Protein Interactions	1.0	null
DG(24:1(15Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3072
PPP3CB	Pathway Commons Protein-Protein Interactions	1.0	null
cyclic-gmp	Phosphosite Textmining Biological Term Annotations	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
MYBPC3	Pathway Commons Protein-Protein Interactions	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705993
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.71807
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86474
DG(20:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71186
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n9/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041736
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36861
TRP channels	Reactome Pathways 2014	1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78153
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057064
DG(16:1(9Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14078
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
HCC366	DepMap CRISPR Gene Dependency	1.0	2.60037
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
DG(22:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.51395
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
DG(16:1(9Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
DG(22:2(13Z,16Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
trpc7	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66165
DG(14:1(9Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
Platelet activation, signaling and aggregation	Reactome Pathways 2014	1.0	null
DES	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
DG(22:1n9/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0909
DG(22:1n9/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96017
DG(18:3n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
SNAP25	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:4n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42691
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
channel	GeneRIF Biological Term Annotations	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5223
DG(24:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29269
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978199
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9461
DG(20:1n9/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
DG(16:1(9Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
MONOMAC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.7336
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71987
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058001
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3621
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.391313
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12508
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3811
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17717
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n7/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
PMC7969799__F1	PFOCR Pathway Figure Associations 2023	1.0	null
DG(24:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
nih-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381003
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52885
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.721921
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62147
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	2.17883
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
DG(18:1n7/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9002
anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.10638
XRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73252
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_Midi 435	HuBMAP ASCT+B Annotations	1.0	null
Gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14267
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-4650-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25041
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.068
DG(18:1(11Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
valproic acid-2700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(14:1(9Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
chromosome deletion; myelodysplastic syndromes	GAD Gene-Disease Associations	1.0	null
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3878
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.960312
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88932
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
PMC3348545-NIHMS263168-supplement-3.pdf-126-SMAD5_SMAD5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3922-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
Cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.168
DG(22:1(13Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
DG(24:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22753
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.57218
DG(22:4(7Z,10Z,13Z,16Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40686
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.322967
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978199
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21689
DG(22:4(7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07176
PNPLA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48006
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.21638
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1513
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959306
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86524
DG(18:2n6/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83538
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1034
DG(20:2n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.82492
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2026
DG(22:2(13Z,16Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598469
DG(18:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4069
PAX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1181
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	1.69281
DG(18:4(6Z,9Z,12Z,15Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1488
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16136
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
DG(14:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550901
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06266
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25354
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71582
DG(20:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mouse	Phosphosite Textmining Biological Term Annotations	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
DG(18:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44264
DG(22:2(13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995913
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
DG(14:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.5781
indicating	GeneRIF Biological Term Annotations	1.0	null
DG(18:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
neostriatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370496
psych	GAD High Level Gene-Disease Associations	1.0	0.300704
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	97.7297
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02344
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.766804
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.967437
gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328628
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4664
Brain_CT2_MGE 249	HuBMAP ASCT+B Annotations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885199
DG(22:4(7Z,10Z,13Z,16Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03736
overnutrition	GWASdb SNP-Disease Associations	1.0	0.452284
DG(20:4(8Z,11Z,14Z,17Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168101
mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.956859
DG(20:2(11Z,14Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:1n9/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
DG(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
gastrointestinal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242672
MORCPR	DepMap CRISPR Gene Dependency	1.0	2.27155
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYL9	Pathway Commons Protein-Protein Interactions	1.0	null
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
NEB	Pathway Commons Protein-Protein Interactions	1.0	null
DG(16:1n7/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
MYL4	Pathway Commons Protein-Protein Interactions	1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.11983
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DG(22:2(13Z,16Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10149
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
DBTRG-05MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77226
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DG(18:2(9Z,12Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:1(13Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21239
DG(20:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2139
NCI-H510 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.628
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83684
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9776
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
DG(22:5n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29265
DG(20:3(8Z,11Z,14Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072157
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:2(9Z,12Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59765
DG(18:1n9/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16502
DG(24:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05563
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Right middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:4n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DG(14:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
felbinac-3061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72561
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell activation	GO Biological Process Annotations 2015	1.0	null
DG(18:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29984
TE9	Achilles Cell Line Gene Essentiality Profiles	1.0	1.47513
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95837
functional respiratory abnormality	GWASdb SNP-Phenotype Associations	1.0	0.587158
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05433
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	0.778061
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32245
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.881204
DG(20:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1(11Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SHMAC5	DepMap CRISPR Gene Dependency	1.0	3.94452
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18399
ZNF143	ENCODE Transcription Factor Targets	1.0	null
colchicine-4614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
DG(20:5n3/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36723
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11377
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885222
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.3769
TNNC2	Pathway Commons Protein-Protein Interactions	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	2.42873
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85103
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00713
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48698
DG(18:1(11Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0361
DG(18:4(6Z,9Z,12Z,15Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
PYGL	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:1(11Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.406425
DG(20:2(11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
DG(18:3n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
DG(20:1(11Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12512
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
DG(18:1(11Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30687
DG(22:4(7Z,10Z,13Z,16Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07309
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0916
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(18:3(9Z,12Z,15Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SW579	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19348
DG(15:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
DG(20:3(5Z,8Z,11Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60978
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62731
HARA	DepMap CRISPR Gene Dependency	1.0	3.22447
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03979
DG(20:4n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Nervous system development	Reactome Pathways 2024	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
DG(18:4(6Z,9Z,12Z,15Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359292
SMC3	ENCODE Transcription Factor Targets	1.0	null
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
BI 749327	DGIdb Drug Targets 2026	1.0	3.30825
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
DG(20:4(5Z,8Z,11Z,14Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DG(22:1(13Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15394
DG(20:3(5Z,8Z,11Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9967
DG(20:1n9/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01615
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938765
DG(24:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6984
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18246
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(20:3(8Z,11Z,14Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87145
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.465335
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72043
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94398
rosiglitazone_mus musculus_gpl8321_gds4021	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(16:1n7/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13684
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.37924
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19558
DG(24:1(15Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17821
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62265
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.42893
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
DG(24:1(15Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06096
EZH2	ENCODE Transcription Factor Targets	1.0	null
DG(18:2(9Z,12Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43182
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
pathwayreview	GeneRIF Biological Term Annotations	1.0	null
DG(22:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39003
homeostasis	GeneRIF Biological Term Annotations	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.341529
DG(24:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79798
MEL-HO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(14:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3127-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DG(18:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77463
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.42085
DG(22:5n3/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00168
DG(14:1(9Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.31506
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10013
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(16:1n7/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580417
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE90019,GSE90020_1_v_3_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12217
22RV1	DepMap CRISPR Gene Dependency	1.0	2.84265
DG(18:1n9/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02213
nci-h69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294223
bacterial-type flagellum filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066602
DG(18:3(6Z,9Z,12Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
DG(16:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
C10	DepMap CRISPR Gene Dependency	1.0	2.64801
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06767
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.988466
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45085
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9547
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
DG(20:1n9/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39909
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01024
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66308
DG(16:0/0:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
VAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65582
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75633
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16342
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48373
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6956
same	GeneRIF Biological Term Annotations	1.0	null
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.64
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059978
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01523
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.729797
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06007
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3274
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.485
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17159
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:2n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
SRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12231
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136183
minoxidil-4216	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(20:3n9/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
DG(18:2(9Z,12Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69777
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
induce	GeneRIF Biological Term Annotations	1.0	null
DG(18:2n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11455
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:1(9Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.049302
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853801
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3626
DAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53379
DG(24:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.048181
nadolol-4021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
receptoroperated	GeneRIF Biological Term Annotations	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29863
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36808
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847996
COLO-741	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64292
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39004
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50709
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17923
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11651
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84979
chronic obstructive pulmonary disease	GWASdb SNP-Disease Associations	1.0	0.685245
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.124
DG(18:1(11Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Porosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64856
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4282
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57568
IA-LM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Platelet homeostasis	Reactome Pathways 2014	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DG(16:1(9Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40126
UNC13B	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55189
homeostatic process	GO Biological Process Annotations 2015	1.0	null
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18068
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
DG(24:1n9/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.771
submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798958
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(14:1(9Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2345
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
Myelodysplastic Syndromes	HuGE Navigator Gene-Phenotype Associations	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572418
RS411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23628
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:3(8Z,11Z,14Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35525
22RV1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3723
DG(20:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.11616
epineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215534
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MD-01A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57756
Effects of PIP2 hydrolysis	Reactome Pathways 2014	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.900181
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
DG(22:1n9/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.399707
DG(18:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
influx	GeneRIF Biological Term Annotations	1.0	null
DG(20:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96688
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
SW837	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50054
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7878
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42722
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.87825
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26668
availability	GeneRIF Biological Term Annotations	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.595255
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59744
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
Iris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.299
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.87
DG(18:2(9Z,12Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610943
DG(14:1n5/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42886
JUND	ENCODE Transcription Factor Targets	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486716
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.38931
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.35875
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50989
DG(24:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32175
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
member	GeneRIF Biological Term Annotations	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
DG(16:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15294
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9597
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1317
store-operated calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
bladder wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.688817
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869016
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208825
Platelet calcium homeostasis	Reactome Pathways 2024	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055612
DG(18:2n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7045
DG(18:1(9Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058205
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5594
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02757
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transition metal ion transport	GO Biological Process Annotations 2015	1.0	null
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28258
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72039
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.26755
DG(24:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
HS737T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56904
TNNT1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.07025
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
DG(18:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
Actin cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
DG(24:1(15Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.305
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00576
HS766T	DepMap CRISPR Gene Dependency	1.0	3.30834
DG(24:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.960744
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN464	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39314
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
DG(22:4(7Z,10Z,13Z,16Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7342
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(16:1n7/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53346
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58171
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7622
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67484
DG(24:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.868529
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84517
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.11327
Ankyrin repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28822
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
DG(18:1(11Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Endostyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21235
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:1n9/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSP90-CDC37 chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
lung	GTEx Tissue Gene Expression Profiles	-1.0	-0.849652
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23935
osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091395
DG(20:4(8Z,11Z,14Z,17Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.47348
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13723
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084958
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5199
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63497
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-864-2994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31469
DG(20:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3n3/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
DG(20:1(11Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
KE37	DepMap CRISPR Gene Dependency	1.0	7.07206
DG(14:1n5/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20942
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.158214
AMILORIDE	DGIdb Drug Targets 2026	1.0	0.413531
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31525
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	130.249
DG(20:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(9Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02615
DG(20:2(11Z,14Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n7/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2(9Z,12Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.138
BV173	CCLE Cell Line Gene Expression Profiles	1.0	1.5309
NFATC3	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
CRCGN015_MCF10A_48H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18222
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72027
DG(15:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81824
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930106
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.264
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10194
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73834
DG(18:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99671
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66912
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
DG(16:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03882
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635167
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2663
DG(20:1n9/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07071
ZNF827	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75965
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01229
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40678
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.09747
TNNI3	Pathway Commons Protein-Protein Interactions	1.0	null
ca2	GeneRIF Biological Term Annotations	1.0	null
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35591
Platelet calcium homeostasis	Reactome Pathways 2014	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(16:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FOXP1_01_209	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58644
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62767
nuclear envelope	GO Cellular Component Annotations 2015	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
swiss-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22069
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYT5	Pathway Commons Protein-Protein Interactions	1.0	null
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5038
Elevation of cytosolic Ca2+ levels	Reactome Pathways 2024	1.0	null
Circular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15126
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73922
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
DG(18:0e/2:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
DG(24:1(15Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28009
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
transient	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45503
DG(20:2(11Z,14Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:2(11Z,14Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
DG(20:4(5Z,8Z,11Z,14Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36339
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060227
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12261
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43324
intracellular part	GO Cellular Component Annotations 2015	1.0	null
epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(18:1(9Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
blood coagulation	GO Biological Process Annotations 2015	1.0	null
DG(15:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16844
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
DG(20:2(11Z,14Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
tolnaftate-4221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.793543
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68161
DG(22:4(7Z,10Z,13Z,16Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC6766969-PATH-249-90-s006.xlsx-TAB_S2_b-Supplementary_Table_S2_b_Top_100_upregulated_and_downregulated_genes_in_TAF15-NR4A3_vs_EWSR1-NR4A3_engineered_cell_models_NR4A3	Rummagene Transcription Factor Associations 2026	1.0	null
PYGB	Pathway Commons Protein-Protein Interactions	1.0	null
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45212
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46588
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68897
DG(20:1(11Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
CRX	ChEA Transcription Factor Targets	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Anchoring junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.168
Carrion's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
DG(20:3(8Z,11Z,14Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	3.239
DG(16:1(9Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16962
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
DG(24:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4511
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6711
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01442
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
carbenoxolone-4093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(20:1n9/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833404
DG(14:1n5/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
TAGLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64263
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52654
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04472
DG(20:3n9/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
HINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69234
modulated	GeneRIF Biological Term Annotations	1.0	null
DG(18:1(9Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MYL3	Pathway Commons Protein-Protein Interactions	1.0	null
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16467
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053432
ion	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DG(22:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2(9Z,12Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128226
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8764
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05489
DG(16:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
camp	Phosphosite Textmining Biological Term Annotations	1.0	null
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
LAMA-84	GDSC Cell Line Gene Expression Profiles	1.0	2.24181
PMC4312948__F7	PFOCR Pathway Figure Associations 2023	1.0	null
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
DG(18:3n3/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35354
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19882
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36924
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24925
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cercopithecus-aethiops	Phosphosite Textmining Biological Term Annotations	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9679
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143216
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
DG(18:4(6Z,9Z,12Z,15Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32931
native	GeneRIF Biological Term Annotations	1.0	null
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54897
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14792
DG(18:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.808443
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	2.0401
DG(18:1n7/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56454
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8249
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.9725
cation	GeneRIF Biological Term Annotations	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05164
TNNT2	Pathway Commons Protein-Protein Interactions	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34253
DG(14:1n5/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47722
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17027
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15294
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.39391
DG(20:3(5Z,8Z,11Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09004
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868449
DG(22:2n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.058405
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959306
DG(18:3(9Z,12Z,15Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0876
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358546
DG(20:4(5Z,8Z,11Z,14Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167227
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55168
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DG(14:0/0:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:2(9Z,12Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
adpkd	GeneRIF Biological Term Annotations	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169618
DG(16:1n7/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73386
DG(20:1n9/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373868
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Platelet activation, signaling and aggregation	Reactome Pathways 2024	1.0	null
cellular cation homeostasis	GO Biological Process Annotations 2015	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	1.0	2.0958
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n7/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DG(18:1(11Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19442
opens	GeneRIF Biological Term Annotations	1.0	null
DG(22:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DG(16:1(9Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842794
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214388
axon guidance	GO Biological Process Annotations 2015	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
DG(18:2(9Z,12Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proliferation	GeneRIF Biological Term Annotations	1.0	null
DG(15:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9987
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221755
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46759
NP3	DepMap CRISPR Gene Dependency	1.0	2.03797
c16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.87455
cellular divalent inorganic cation homeostasis	GO Biological Process Annotations 2015	1.0	null
DG(20:3(5Z,8Z,11Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02301
DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PPFIA3	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscarinic	GeneRIF Biological Term Annotations	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6273
DG(18:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58038
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13654
H4C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84916
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22205
paracetamol-3025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4n3/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome Pathways 2014	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16324
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
DG(14:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1412
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:2n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7423
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25427
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13292
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25168
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
calcium	GeneRIF Biological Term Annotations	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960979
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870756
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPFIA1	Pathway Commons Protein-Protein Interactions	1.0	null
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.123191
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
RB1_KD_GSE50532_593_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3(6Z,9Z,12Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.433
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
Tube foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
DG(14:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4965
DG(18:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77526
DG(20:4(8Z,11Z,14Z,17Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.297291
DG(18:1(9Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus taeniae	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602088
NCAPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13215
congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133098
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.059572
DG(20:3(8Z,11Z,14Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54883
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9774
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:2n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n6/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0304
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88105
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842083
cellular metal ion homeostasis	GO Biological Process Annotations 2015	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63719
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64904
DG(20:4(8Z,11Z,14Z,17Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061699
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84835
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20381
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
DG(18:1n9/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
TNNC1	Pathway Commons Protein-Protein Interactions	1.0	null
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.455
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.505944
myb_16205643_mcf7_gof_human_gpl96_gse2815	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.470065
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14267
DG(18:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.37265
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38114
DG(14:1n5/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
platelet activation	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4526
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90103
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9953
OAW42	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02075
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.197449
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01757
DG(16:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4n3/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.02
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.903701
nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728975
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34643
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945046
DG(18:1n7/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Ion channel transport	Reactome Pathways 2014	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16566
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8359
DG(24:1n9/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03562
Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(16:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
DG(18:1(11Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.13898
DG(20:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34452
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
DG(20:4(5Z,8Z,11Z,14Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
DG(18:3(6Z,9Z,12Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.474
DG(18:1(11Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.064
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
DG(18:2(9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53197
elusive	GeneRIF Biological Term Annotations	1.0	null
DG(20:2(11Z,14Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4n3/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
calcium	Phosphosite Textmining Biological Term Annotations	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1843
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51413
DG(18:3n6/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21852
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
TRP channels	Reactome Pathways 2024	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53259
DG(22:5n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DG(20:1(11Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7104
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833521
basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1717
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93638
DG(18:4n3/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4211
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	3.18931
SF295	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.39625
DG(20:2n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(14:1n5/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838223
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71531
PLEKHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38735
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	2.54486
Urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53539
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978199
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32364
neuron projection guidance	GO Biological Process Annotations 2015	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09124
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376494
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47544
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274835
DG(20:2(11Z,14Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n7/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Unipolar Depression	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75547
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12568
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040997
DG(20:3(8Z,11Z,14Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0135
DG(15:0/0:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869124
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8E_Het1A-GATA6_2d_5x_open-Nearest_Ensembl_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
TEAD4	ENCODE Transcription Factor Targets	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.71502
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92662
DG(20:1n9/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
creb	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0257
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29355
HDAC2	ENCODE Transcription Factor Targets	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955996
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6514
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
PMC5671979__F6	PFOCR Pathway Figure Associations 2023	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48959
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n9/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3036
IMR32	DepMap CRISPR Gene Dependency	1.0	3.37615
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3891
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70347
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
formation	GeneRIF Biological Term Annotations	1.0	null
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34532
ligand-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
DG(18:1(9Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
La<sup>3+</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3(9Z,12Z,15Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.400628
DG(18:1(11Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40043
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32003
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F2	ChEA Transcription Factor Targets	1.0	null
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84012
mania	GWASdb SNP-Phenotype Associations	1.0	0.762459
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.66418
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DG(20:1(11Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30802
DG(20:0/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
DG(20:3(5Z,8Z,11Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.718292
T3M5	DepMap CRISPR Gene Dependency	1.0	4.45864
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
P-388D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.292157
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857281
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56273
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
PMC4312948__F7	PFOCR Pathway Figure Associations 2024	1.0	null
DG(16:1(9Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.1488
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08404
EOL1	CCLE Cell Line Gene Expression Profiles	1.0	1.90261
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73551
DG(20:3(5Z,8Z,11Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
cation channel complex	GO Cellular Component Annotations 2025	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96209
trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905404
germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.236324
Trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
DG(20:3(8Z,11Z,14Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
P31FUJ	CCLE Cell Line Gene Expression Profiles	1.0	1.86981
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71648
DG(20:4(8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72443
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47062
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48689
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3(6Z,9Z,12Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43097
DG(22:2(13Z,16Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11377
DG(15:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
3T3-Swiss albino cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.005
DG(18:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.37416
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57782
chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52635
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16376
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98255
bipolar disorder	GAD Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.952495
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
DG(18:3(9Z,12Z,15Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2193
DG(16:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109558
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74698
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66727
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0937
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.802
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4357
DG(22:4(7Z,10Z,13Z,16Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15673
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38251
Stimuli-sensing channels	Reactome Pathways 2014	1.0	null
DG(14:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(14:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
DG(20:4n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61157
DG(15:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:1(15Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24797
PWWP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86007
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DG(16:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.272953
DG(20:1(11Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5038
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571219
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
DG(18:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111498
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.84477
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52203
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13583
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93464
DG(20:3(8Z,11Z,14Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	3.29493
Sleep duration (short sleep)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
DG(20:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
G alpha (q) signalling events	Reactome Pathways 2024	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26972
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179823
DG(20:1(11Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAUDI	CCLE Cell Line Gene Expression Profiles	1.0	1.9403
DG(18:4(6Z,9Z,12Z,15Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31362
gastric antrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85415
DG(20:3n9/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8316
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5629
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49874
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42693
short	GeneRIF Biological Term Annotations	1.0	null
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.95174
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490619
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070309
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55188
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
DG(20:4(5Z,8Z,11Z,14Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37328
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68074
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(24:1n9/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
clone9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
CTU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62151
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29257
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36674
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:4n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.788733
OAG	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
DG(14:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
common	GeneRIF Biological Term Annotations	1.0	null
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33273
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212936
perinuclear region of cytoplasm	GO Cellular Component Annotations 2015	1.0	null
DG(20:3(5Z,8Z,11Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9389
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938148
pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.590558
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
DG(18:2(9Z,12Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CNGA1	Pathway Commons Protein-Protein Interactions	1.0	null
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0904
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117731
DG(20:1(11Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873147
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26441
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854527
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3778
disease	GWASdb SNP-Disease Associations	1.0	0.059905
DG(24:1(15Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14417
iris dilator muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09208
DG(20:3n9/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6761
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9094
DG(20:3(5Z,8Z,11Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05772
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15505
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66288
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886206
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060514
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(22:1(13Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3(6Z,9Z,12Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
DG(22:1n9/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04145
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25607
pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362646
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
DG(20:3n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19252
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43664
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338914
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(20:4(5Z,8Z,11Z,14Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
DG(20:0/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
longitudinal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.780648
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
Platelet homeostasis	Reactome Pathways 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:2n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:1(13Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08074
DG(20:4(5Z,8Z,11Z,14Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
DG(14:0/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
CACNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19288
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
stomach smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76769
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68669
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.89744
DG(22:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420766
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
kidney disease	GWASdb SNP-Disease Associations	1.0	1.08533
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heteromeric	GeneRIF Biological Term Annotations	1.0	null
DG(18:3(9Z,12Z,15Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
Netrin-1 signaling	Reactome Pathways 2014	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85968
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01482
DG(16:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52296
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
DG(20:3(8Z,11Z,14Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04091
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02205
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80435
DG(18:4(6Z,9Z,12Z,15Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12786
DG(15:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.122881
DG(15:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83699
hsa-miR-4488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
DG(22:1n9/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:3(8Z,11Z,14Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(24:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(20:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18265
DG(20:1(11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31678
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
adherens junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89518
Prostate adenocarcinoma_PRAD_TCGA-EJ-5542-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(16:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.86034
DG(18:1(9Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PXN	Pathway Commons Protein-Protein Interactions	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33528
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
ATG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39016
DG(18:2(9Z,12Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Terminal loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
SW872	GDSC Cell Line Gene Expression Profiles	-1.0	-2.73977
DG(20:5n3/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NO-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.996324
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71906
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:3(8Z,11Z,14Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873147
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
propranolol-3059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829629
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18335
DG(18:1(9Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.286
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567626
lung disease	GWASdb SNP-Disease Associations	1.0	0.346515
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084981
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2708-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(22:2(13Z,16Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
(+/-)-catechin-3012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
DG(24:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30388
DG(18:1(11Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37286
DG(16:1(9Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.76534
participate	GeneRIF Biological Term Annotations	1.0	null
DG(22:1(13Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Transient receptor potential channel, canonical	InterPro Predicted Protein Domain Annotations	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.318534
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.903529
DG(18:3(6Z,9Z,12Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbacholinduced	GeneRIF Biological Term Annotations	1.0	null
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44467
DG(20:3n9/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.942
CRCGN014_HEPG2_3H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28499
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-substrate junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.168
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
DG(18:2(9Z,12Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71937
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53267
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6355
DG(18:1n9/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
SORBS1	Pathway Commons Protein-Protein Interactions	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9685
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00898
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26379
DG(18:1(9Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.982386
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05935
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01139
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0687
Mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
DG(18:1(9Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94596
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056249
DG(16:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14792
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0275
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36611
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.63929
KCL22	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49729
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37408
DG(22:1(13Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364886
STX1A	Pathway Commons Protein-Protein Interactions	1.0	null
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38001
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
DG(22:5n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
DG(18:1(11Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35301
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
bronchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199681
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2081	GDSC Cell Line Gene Expression Profiles	1.0	2.03904
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14417
DG(14:1(9Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.2263
DG(18:4(6Z,9Z,12Z,15Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n9/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
cellular calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88104
DG(18:3(6Z,9Z,12Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
FOXD4L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30813
DG(22:4n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20477
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13471
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06658
RERFLCAD2	CCLE Cell Line Gene Expression Profiles	1.0	1.36435
NCI-H1993	GDSC Cell Line Gene Expression Profiles	1.0	1.44316
DG(20:3(5Z,8Z,11Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GMS-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8394-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4581
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8554
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
forming	GeneRIF Biological Term Annotations	1.0	null
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54489
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34521
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5671979__F6	PFOCR Pathway Figure Associations 2024	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	3.4513
DG(18:3(6Z,9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DG(20:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8586
DG(24:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9984
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3519
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
DG(22:1n9/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32854
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anchoring junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38664
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n7/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MT-ATP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08708
DG(15:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82262
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.586427
SW1573	CCLE Cell Line Gene CNV Profiles	1.0	1.47852
DG(22:2(13Z,16Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35736
SIN3B	ChEA Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05605
DG(20:3(8Z,11Z,14Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1071-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
DG(18:1n7/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.701899
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77392
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1115
DG(22:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DG(15:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
STXBP1	Pathway Commons Protein-Protein Interactions	1.0	null
CEND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14428
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54119
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13125
DG(14:1(9Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(9Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30878
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35262
small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.693719
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
POR_KO_GDS1678_761_mouse_ILEUM	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4595
DG(20:2(11Z,14Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
G alpha (q) signalling events	Reactome Pathways 2014	1.0	null
gastric corpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447576
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3668
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.82736
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53906
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18632
submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
DG(20:3(8Z,11Z,14Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12924
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6808
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.3704
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L1CAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12821
DG(18:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
PMC11046693-pnas.2320938121.sapp.pdf-123-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190524
DG(20:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CAAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47501
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243158
DG(15:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03979
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61607
DG(20:2(11Z,14Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TE15	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25008
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
DG(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2023
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
DG(18:3(9Z,12Z,15Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CADOES1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23915
DG(20:3(5Z,8Z,11Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4295
DG(20:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
DG(20:3n9/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.202538
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.65092
DG(22:5(4Z,7Z,10Z,13Z,16Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41449
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0576
DG(18:2(9Z,12Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42172
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.313915
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
modes	GeneRIF Biological Term Annotations	1.0	null
DG(20:3(5Z,8Z,11Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93004
DG(20:4(8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45551
MMAC-SF	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44936
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
myometrial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542963
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.478773
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.97559
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083714
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(20:3(5Z,8Z,11Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955556
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77059
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Gastric antrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874362
G protein-coupled receptor homodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
Elevation of cytosolic Ca2+ levels	Reactome Pathways 2014	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55882
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.733089
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069177
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.207084
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68838
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11335
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894628
DG(18:4(6Z,9Z,12Z,15Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03595
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.14303
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25859
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	3.05256
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(20:4n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30042
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.651371
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.03891
DG(20:1(11Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36185
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
mood disorder	GWASdb SNP-Disease Associations	1.0	0.347293
TNNI2	Pathway Commons Protein-Protein Interactions	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03514
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
DG(18:2(9Z,12Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Detrusor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	GeneRIF Biological Term Annotations	1.0	null
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion transport	GO Biological Process Annotations 2015	1.0	null
DG(20:2(11Z,14Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
DG(15:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17892
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.535772
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492182
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063028
arterial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23961
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70781
DG(22:5(4Z,7Z,10Z,13Z,16Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
suppressed	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(15:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40743
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.273
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4538
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067108
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60919
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06663
Signaling by GPCR	Reactome Pathways 2014	1.0	null
MYL1	Pathway Commons Protein-Protein Interactions	1.0	null
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34124
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24706
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.61949
DG(18:1n7/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31672
Bipolar Disorder	dbGAP Gene-Trait Associations	1.0	0.073818
DG(20:3(5Z,8Z,11Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4468
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.269878
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17753
SW900	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7636
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3039
DG(18:3(6Z,9Z,12Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3437
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62171
DG(18:3(9Z,12Z,15Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67354
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11786
DG(15:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DG(15:0/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3907
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91345
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37372
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829847
autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51453
DG(22:5n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492572
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56701
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.742
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19264
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19604
DG(20:4(8Z,11Z,14Z,17Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
biological_process	GO Biological Process Annotations 2015	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.869084
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27352
Osteoclastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58907
DG(18:3(6Z,9Z,12Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00205
DG(20:1n9/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_Midi 435	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
DG(20:3n9/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
divalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13697
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38785
DG(22:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14866
COLO741	Achilles Cell Line Gene Essentiality Profiles	1.0	1.69805
2-APB	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
DG(14:0/0:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29501
DG(20:1(11Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.502357
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44918
DG(16:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24211
cloning	GeneRIF Biological Term Annotations	1.0	null
DG(18:3(6Z,9Z,12Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17187
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546929
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87351
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984408
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.8823
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
DG(14:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
organelle envelope	GO Cellular Component Annotations 2015	1.0	null
DG(22:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Trench fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	2.14288
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.898805
DG(18:1n7/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
SSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99906
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55493
DG(20:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
CME1	DepMap CRISPR Gene Dependency	1.0	2.11882
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46161
DG(20:3(5Z,8Z,11Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(5Z,8Z,11Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
DG(20:3(5Z,8Z,11Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0008
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	2.7447
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
DG(14:1n5/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855646
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1939
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74518
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69331
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49036
DG(18:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857281
calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08612
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057738
DG(24:1n9/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47766
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0445
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05352
DG(22:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18026
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRPC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11094182-41408_2024_1061_MOESM18_ESM.xlsx-S17_TP53_genes_signatures-Supplementary_Table_S17_Reported_TP53_target_genes_and_gene_signatures_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
DG(20:3(8Z,11Z,14Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
cos-cells	Phosphosite Textmining Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64L-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tracheal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312595
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08723
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76663
SH045	DGIdb Drug Targets 2026	1.0	2.2055
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
detrusor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.757845
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EDD_DEPLETION_GDS2445_116_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-2.77455
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.778613
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9798
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28203
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1676
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0017
trpc1	GeneRIF Biological Term Annotations	1.0	null
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.440274
DG(24:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(5Z,8Z,11Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ECC2	DepMap CRISPR Gene Dependency	1.0	2.19263
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51027
TGBC11TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.72324
DG(15:0/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08644
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320077
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
iris smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.73728
sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32238
DG(22:4(7Z,10Z,13Z,16Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC7017417__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF217	ChEA Transcription Factor Targets	1.0	null
TPM1	Pathway Commons Protein-Protein Interactions	1.0	null
DG(14:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4981
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.7897
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DG(20:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
blymphocytes	GeneRIF Biological Term Annotations	1.0	null
DG(20:1(11Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32875
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.043
TPM3	Pathway Commons Protein-Protein Interactions	1.0	null
TNNI1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19W-06A-41R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16438
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.53919
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860768
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00492
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Longitudinal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.402
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.863736
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.85
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99864
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:0/0:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46331
DG(16:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FADU	GDSC Cell Line Gene Expression Profiles	1.0	1.50294
DG(22:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
PMC5503541-oncotarget-08-38399-s003.docx-1-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
TTF2	ChEA Transcription Factor Targets	1.0	null
TCF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3753
DG(20:4(5Z,8Z,11Z,14Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71516
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
DG(24:0/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1(11Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36953
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:1n9/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
storeoperated	GeneRIF Biological Term Annotations	1.0	null
DG(18:2n6/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
candidate	GeneRIF Biological Term Annotations	1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.78984
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.565923
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.495894
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590036
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.340397
DG(14:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8805
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:4n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL24	DepMap CRISPR Gene Dependency	1.0	4.0712
cell part	GO Cellular Component Annotations 2015	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07184
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23892
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.157729
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
DG(18:1(9Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1(11Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45884
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23434
iris	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.73728
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854527
DG(16:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00035
DG(22:5(7Z,10Z,13Z,16Z,19Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LMOD1	Pathway Commons Protein-Protein Interactions	1.0	null
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22079
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
A427	GDSC Cell Line Gene Expression Profiles	1.0	1.65118
DG(22:1n9/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
PYGM	Pathway Commons Protein-Protein Interactions	1.0	null
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77317
DG(18:2n6/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LARIXYL ACETATE	DGIdb Drug Targets 2026	1.0	3.30825
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
IGROV1	DepMap CRISPR Gene Dependency	1.0	3.02886
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58298
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8756
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02438
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
DG(18:3(9Z,12Z,15Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.495309
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.360395
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(24:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Brain_CT2_MGE 249	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99011
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.20852
DG(14:1(9Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n7/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n7/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969936
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.862782
hsa-miR-3176	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50467
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSK3A_knockdown_203_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.70308
REST	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
PRKG1	PhosphoSitePlus Substrates of Kinases	1.0	null
DG(14:1(9Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1n9/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
venom duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.816068
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56899
Colon muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24106
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76724
Bladder wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
iris sphincter muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.82401
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7142
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
DG(18:1(9Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34982
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5116
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84448
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79688
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.967437
OVKATE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
DG(22:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.70365
DG(22:1(13Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE133286,GSE133299_1_v_0_tepoxalin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03746
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04865
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(15:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48694
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18191
coagulation	GO Biological Process Annotations 2015	1.0	null
DG(14:1n5/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SKOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.62087
myeloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080539
DG(18:3(9Z,12Z,15Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0825
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:3(8Z,11Z,14Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56947
DG(15:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
YTHDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69971
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Iris smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.433
Hypertrophy	CTD Gene-Disease Associations	1.0	1.14781
RARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0512
DG(24:1(15Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:1n9/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
NCI-H1299	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43478
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15442
DG(18:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
DG(18:3n3/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Ankyrin repeat	InterPro Predicted Protein Domain Annotations	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.57655
NOMO-1	GDSC Cell Line Gene Expression Profiles	1.0	1.42552
DG(18:4(6Z,9Z,12Z,15Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853801
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.689
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70488
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627889
Stimuli-sensing channels	Reactome Pathways 2024	1.0	null
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
DG(22:2(13Z,16Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC7969799__F1	PFOCR Pathway Figure Associations 2024	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30812
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057828
DG(16:0/0:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65541
alcohol binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1431
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45295
HSD3B7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27286
DG(22:4(7Z,10Z,13Z,16Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:2(9Z,12Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876107
Body fat percentage	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25503
HUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28316
PMC6279925__F4	PFOCR Pathway Figure Associations 2023	1.0	null
UMC-11	GDSC Cell Line Gene Expression Profiles	1.0	1.70442
DG(15:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01771
DG(14:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93763
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
DG(18:3(9Z,12Z,15Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34204
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0405
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48575
DG(24:1(15Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN010_HEPG2_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12218
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930066
DG(20:3n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
environment	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10932
DG(18:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81179
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU283	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96464
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5744
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.201479
DG(20:4(8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2(9Z,12Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85085
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08686
UNC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42654
DG(16:1n7/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
CMK115	CCLE Cell Line Gene Expression Profiles	1.0	1.61229
JNK_KO_GDS3001_531_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50593
CRCGN008_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0122
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28854
neostigmine bromide-6735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
amnestic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.407172
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.762397
DG(22:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
PRKCB	Pathway Commons Protein-Protein Interactions	1.0	null
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86816
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.67279
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4103
MYH6	Pathway Commons Protein-Protein Interactions	1.0	null
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:3n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37328
DG(20:5(5Z,8Z,11Z,14Z,17Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TPM4	Pathway Commons Protein-Protein Interactions	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.24992
DG(16:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13974
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51006
DG(20:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989667
hemostasis	GO Biological Process Annotations 2015	1.0	null
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:1(15Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946424
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856021
DG(18:4(6Z,9Z,12Z,15Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22194
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
Stomach smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
Hmgn1_KO_GDS5010_405_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	7.43057
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
496100290_PCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32211
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Role of second messengers in netrin-1 signaling	Reactome Pathways 2014	1.0	null
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
hsa-miR-4697-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54267
smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517284
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86926
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
DG(16:0/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54631
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular	GeneRIF Biological Term Annotations	1.0	null
Submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
CBX3	ENCODE Transcription Factor Targets	1.0	null
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27531
localization	GO Biological Process Annotations 2015	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
RPL39L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75658
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65057
DG(14:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.1202
myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19089
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3287
SAP30	ENCODE Transcription Factor Targets	1.0	null
DG(18:2n6/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59247
DG(16:0/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.4551
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050424
DG(14:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18135
DG(18:1(9Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:0/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8165
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.998037
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
DG(16:1n7/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1(11Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14156
cellular process	GO Biological Process Annotations 2015	1.0	null
subfamily	GeneRIF Biological Term Annotations	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
0179445-0000-4755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
DG(20:4(8Z,11Z,14Z,17Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CDC25C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19913
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.848169
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYBPC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9316
DG(20:3n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89395
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.71685
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510206
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20375
DG(18:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RASGRP2	Pathway Commons Protein-Protein Interactions	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
DG(18:3(9Z,12Z,15Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PEAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0507
DG(20:2(11Z,14Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059764
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09175
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.793
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06905
DG(20:2(11Z,14Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85331
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.72393
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.433
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08804
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061449
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39272
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
DG(18:1(11Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/20:3n9)	HMDB Metabolites of Enzymes	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14844
DG(22:1(13Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44535
link	GeneRIF Biological Term Annotations	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
DG(14:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80389
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enhanced	GeneRIF Biological Term Annotations	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DG(20:4(5Z,8Z,11Z,14Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.559652
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0212
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40172
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.27538
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
DG(24:1(15Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07768
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8699
DG(18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09363
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.38743
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.49151
WSUDLCL2	CCLE Cell Line Gene Expression Profiles	1.0	2.24345
DG(24:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
PRKG1	KEA Substrates of Kinases	1.0	null
SLC17A7	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
DG(22:1(13Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25458
YH13	DepMap CRISPR Gene Dependency	1.0	3.7068
DG(24:1(15Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00391
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.865577
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08064
DG(20:0/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17931
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377773
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
REST_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.532274
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886206
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91661
DG(16:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08798
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12377
DG(18:3(9Z,12Z,15Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
DG(20:2(11Z,14Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
DG(18:1(9Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17772
Chromosome Deletion	HuGE Navigator Gene-Phenotype Associations	1.0	null
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09492
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0118
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03947
SW620	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46585
DG(22:1n9/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.673321
DG(20:3n9/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.789191
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92287
DG(20:2(11Z,14Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
pulmonary edema	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1936
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.892093
ML 7	CTD Gene-Chemical Interactions	1.0	null
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
TRPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62733
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220378
Duration Of Sleep	DisGeNET Gene-Phenotype Associations	1.0	null
DG(24:1n9/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.677
DG(16:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
maxillary nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.609332
DDX31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28995
PMC3470785-NIHMS377161-supplement-14.pdf-109-PDX1_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
prednicarbate-5119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02085
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GH4-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(20:3n9/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
calcium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
DG(18:3(9Z,12Z,15Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
DG(22:4(7Z,10Z,13Z,16Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
DG(18:3n3/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.76745
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
DG(24:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20965
DG(18:1(11Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
DOV13	DepMap CRISPR Gene Dependency	1.0	2.66133
ca2permeable	GeneRIF Biological Term Annotations	1.0	null
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.553
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11646
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212936
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
DG(18:1(9Z)/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1855
PCI-4B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CGTHW1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.73515
Role of second messengers in netrin-1 signaling	Reactome Pathways 2024	1.0	null
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
2-APB	DGIdb Drug Targets 2026	1.0	0.413531
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(14:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4n6/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23148
protein binding	GO Molecular Function Annotations 2015	1.0	null
DG(14:1(9Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92001
Myometrial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44114
Iris dilator muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
comprised	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.27715
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57727
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4004
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3645
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79233
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.87568
DG(18:2(9Z,12Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.09083
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13548
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63127
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49368
DG(20:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11735
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.70246
DG(20:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11455
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32385
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.983
asthma	GWASdb SNP-Disease Associations	1.0	0.685245
DG(22:4n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
DG(18:1(11Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:4(6Z,9Z,12Z,15Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:3(9Z,12Z,15Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486716
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17027
DG(18:2(9Z,12Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219047
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02078
DG(18:1(9Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879699
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917757
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81753
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	1.0	1.41507
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30219
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00931
DG(20:1(11Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.937488
DG(20:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
DG(22:1n9/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46674
TTN	Pathway Commons Protein-Protein Interactions	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.36946
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3645
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64811
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7674
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0655
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
DG(18:2(9Z,12Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.047818
DG(20:2(11Z,14Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.102643
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9101
MAN1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82251
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66779
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3363
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
DG(18:3n6/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98004
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1455
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
trpc3	GeneRIF Biological Term Annotations	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72443
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:1n9/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
MX1	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.01486
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
DG(16:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92997
DG(18:3(9Z,12Z,15Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9684
KCIMOH1	DepMap CRISPR Gene Dependency	1.0	5.80815
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37469
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.351762
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.05312
DG(18:2(9Z,12Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
DG(16:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34595
IGROV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.56472
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
DG(18:3n6/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
496100379_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22815
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568025
DG(22:1(13Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2081
holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.465794
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:2n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4789
DG(20:1n9/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2(9Z,12Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065363
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.435
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39795
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51666
SNU620	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75635
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53551
C6 glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
CAVIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95139
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
DG(18:1n9/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29931
large cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.469954
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3484
SH10TC	DepMap CRISPR Gene Dependency	1.0	2.34131
DG(14:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19585
DG(20:2n6/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478534
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08855
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278251
ERG_01_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.00487
trpm7	GeneRIF Biological Term Annotations	1.0	null
DG(16:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.46658
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51271
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34183
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852733
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03084
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
DG(18:0/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4122
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516104
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.789796
DG(20:4(8Z,11Z,14Z,17Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.048999
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492182
DG(18:1(9Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
A704	CCLE Cell Line Gene Expression Profiles	1.0	2.40536
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67985
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63747
DG(18:3n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10814
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(18:3(9Z,12Z,15Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0558
PYRAZOLOPYRIMIDINE 4N	DGIdb Drug Targets 2026	1.0	2.2055
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12374
SMUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68887
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80291
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063801
calcium ion homeostasis	GO Biological Process Annotations 2015	1.0	null
DG(20:5(5Z,8Z,11Z,14Z,17Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03719
VCL	Pathway Commons Protein-Protein Interactions	1.0	null
DG(20:2n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10596
DG(20:2n6/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471927
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
DG(20:3n6/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.207451
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cyclic-amp-dependent-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50174
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298371
DG(24:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
DG(24:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73148
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
DG(18:3(9Z,12Z,15Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(5Z,8Z,11Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21186
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.622639
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8299
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0434
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
DG(22:0/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
regulation of body fluid levels	GO Biological Process Annotations 2015	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
MYH8	Pathway Commons Protein-Protein Interactions	1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49856
DG(22:0/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
DG(20:3n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-3673	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
DG(20:3(8Z,11Z,14Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DMD	Pathway Commons Protein-Protein Interactions	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16805
NCI-H69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
DG(14:0/0:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05464
DG(20:4(5Z,8Z,11Z,14Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(11Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20185
DG(22:1(13Z)/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92351
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.42081
DG(24:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:1(11Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.729
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
LU165	DepMap CRISPR Gene Dependency	1.0	3.21888
DG(16:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917757
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:3(8Z,11Z,14Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874845
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	1.4713
DG(22:2(13Z,16Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1n9/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
DG(24:0/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12861
medial parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43458
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
DG(16:0/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:0/0:0/20:0)	HMDB Metabolites of Enzymes	1.0	null
activated	GeneRIF Biological Term Annotations	1.0	null
DG(22:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
SEPTIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90206
DG(20:1n9/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.307701
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.154
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051497
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03882
cis-golgi network	GO Cellular Component Annotations 2015	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
DG(20:0/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32205
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4699
CHD7	ENCODE Transcription Factor Targets	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06617
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61613
store-operated calcium channel activity	GO Molecular Function Annotations 2015	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959306
TP53INP2_OE_GDS5054_385_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
liminal part of the r5 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03643
Polyphosphate kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
DG(18:4n3/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857281
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66778
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whereas	GeneRIF Biological Term Annotations	1.0	null
bacterial-type flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75372
DG(20:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DG(16:1(9Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1183
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52521
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64631
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37609
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16443
preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384766
DG(18:0/0:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8987
DG(14:1(9Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48052
Transient receptor ion channel domain	InterPro Predicted Protein Domain Annotations	1.0	null
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.34341
cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
brain	GTEx Tissue Gene Expression Profiles	1.0	0.840389
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24594
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.114
DG(16:1n7/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00109
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.942
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33874
muscularis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.891798
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(14:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96357
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41185
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14336
DG(15:0/0:0/16:0)	HMDB Metabolites of Enzymes	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02195
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:3(9Z,12Z,15Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(18:2(9Z,12Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38967
DG(18:4(6Z,9Z,12Z,15Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885222
PPFIA4	Pathway Commons Protein-Protein Interactions	1.0	null
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26637
DG(20:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8E_Het1A-GATA6_2d_5x_open-Gene_Name_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Primary motor area, Layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17445
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41803
DG(20:1n9/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23787
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
receptoractivated	GeneRIF Biological Term Annotations	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873147
DG(16:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(24:0/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25902
DG(22:5(7Z,10Z,13Z,16Z,19Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3153
single-organism localization	GO Biological Process Annotations 2015	1.0	null
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
DG(18:2n6/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01147
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30025
DG(18:1n7/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/14:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28941
NCC021	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(15:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13999
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organum vasculosum laminae terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
DG(18:3n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49836
DG(14:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21365
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847992
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03595
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65207
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30559
DG(18:2(9Z,12Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/0:0/18:1n7)	HMDB Metabolites of Enzymes	1.0	null
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61184
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95411
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47761
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19592
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24272
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.761216
DG(20:4(8Z,11Z,14Z,17Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40424
DG(22:1n9/0:0/24:1n9)	HMDB Metabolites of Enzymes	1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93334
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2618
DG(22:1(13Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(8Z,11Z,14Z,17Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4798
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1323
DG(18:1n9/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.786
DG(20:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922752
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
DG(16:1(9Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
phospholipase	GeneRIF Biological Term Annotations	1.0	null
DG(22:5(4Z,7Z,10Z,13Z,16Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mg2	GeneRIF Biological Term Annotations	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.323825
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2915
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DG(18:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85181
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
DG(20:4n3/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04552
DG(16:1n7/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
Gastric corpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.328834
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057064
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885199
DG(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(8Z,11Z,14Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
appears	GeneRIF Biological Term Annotations	1.0	null
DG(14:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.762459
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	2.15798
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83026
Transient receptor potential channel, canonical 7	InterPro Predicted Protein Domain Annotations	1.0	null
substance dependence	GWASdb SNP-Disease Associations	1.0	0.262431
DG(14:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32159
DG(14:0/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51227
DG(20:4(8Z,11Z,14Z,17Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.32551
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.506279
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
DG(18:3n6/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5109
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4941
DG(18:4(6Z,9Z,12Z,15Z)/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.870217
monoatomic ion channel complex	GO Cellular Component Annotations 2025	1.0	null
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83057
PCNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04796
DG(14:1(9Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46587
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08804
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-LM	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43713
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
DG(15:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/18:1n9)	HMDB Metabolites of Enzymes	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19534
GFI1_KO_GDS4204_147_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84766
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36642
cellular chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38004
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32989
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.052443
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48956
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61557
DG(18:2(9Z,12Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317545
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90731
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34618
DG(20:4(5Z,8Z,11Z,14Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1n5/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10606
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92922
mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43414
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01775
DG(20:2n6/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
cell-substrate adherens junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
locus coeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12216
DG(20:3(5Z,8Z,11Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
manganese ion transport	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916781
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882343
PSEN2	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13654
suprofen-3005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277549
lead	GeneRIF Biological Term Annotations	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469211
DG(20:2n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84713
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.07724
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416957
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
DG(24:1n9/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(6Z,9Z,12Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:1(9Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(15:0/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28489
trpc6	GeneRIF Biological Term Annotations	1.0	null
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.287952
DG(18:0/0:0/22:4n6)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/18:2(9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
calcium channel activity	GO Molecular Function Annotations 2015	1.0	null
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.385789
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08447
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13195
DG(22:4n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1(15Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8752
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055894
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988851
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4103
exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510206
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDMYZ	DepMap CRISPR Gene Dependency	1.0	4.10732
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87207
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
DG(18:3n6/0:0/20:4n3)	HMDB Metabolites of Enzymes	1.0	null
female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243158
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58108
RCOR3	ChEA Transcription Factor Targets	1.0	null
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.821
DG(22:5(4Z,7Z,10Z,13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
CALM1	Pathway Commons Protein-Protein Interactions	1.0	null
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
UM-UC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:4n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
DG(20:3(5Z,8Z,11Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41856
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.346515
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534251
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:0/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26045
TCF7	ChEA Transcription Factor Targets	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
DG(15:0/0:0/18:2n6)	HMDB Metabolites of Enzymes	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0699
MSRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60459
muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.49844
DG(22:4n6/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(22:4(7Z,10Z,13Z,16Z)/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87084
DG(20:4(8Z,11Z,14Z,17Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05215
DG(15:0/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(24:1n9/0:0/18:3n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
DG(22:0/0:0/20:5n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
UNC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79918
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042923
DG(24:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
DG(20:3(5Z,8Z,11Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05204
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
CMK86	CCLE Cell Line Gene Expression Profiles	1.0	1.40349
sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452584
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0815
NFE2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44222
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(24:0/15:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
NFATC1	Pathway Commons Protein-Protein Interactions	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27326
GSE173262_2_v_5_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59858
DG(18:3(6Z,9Z,12Z)/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14063
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-BACH1_BACH1	Rummagene Transcription Factor Associations 2026	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43403
DG(20:4(8Z,11Z,14Z,17Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100964
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86953
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
DG(22:1(13Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:2(11Z,14Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18384
SNU5	DepMap CRISPR Gene Dependency	1.0	4.39608
nci-h510 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25816
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10335
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7509
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8758
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:2n6/0:0/18:3n3)	HMDB Metabolites of Enzymes	1.0	null
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0994
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37871
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.28179
DG(18:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.363716
agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.585497
DG(14:0/22:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
SNU489	CCLE Cell Line Gene CNV Profiles	1.0	1.41927
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.904978
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44899
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.97559
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051042
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862067
DG(24:1n9/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ligand-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
DG(20:3(8Z,11Z,14Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DG(20:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(18:1(9Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/22:5(7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03882
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03158
DG(16:0/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14238
succinylsulfathiazole-4265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:3(6Z,9Z,12Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
VEGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4993
DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8785
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14695
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42689
cation homeostasis	GO Biological Process Annotations 2015	1.0	null
furazolidone-3019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DG(18:3(6Z,9Z,12Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99845
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1352
DG(14:1n5/0:0/20:2n6)	HMDB Metabolites of Enzymes	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(18:1(11Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1536
Axon guidance	Reactome Pathways 2014	1.0	null
DG(22:0/0:0/22:5n3)	HMDB Metabolites of Enzymes	1.0	null
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073071
TRPC1-TRPC3-TRPC7 complex	CORUM Protein Complexes	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8432
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973503
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BZRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46001
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
Tracheal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37162
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DG(15:0/18:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172544
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(20:3(5Z,8Z,11Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66808
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.767368
pd5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.166878
DG(22:0/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1n7/0:0/16:1n7)	HMDB Metabolites of Enzymes	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02817
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13654
DG(20:2(11Z,14Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9566
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42117
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
DG(22:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:6n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7106
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83226
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0308
DG(22:2(13Z,16Z)/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(14:0/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.34
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08957
DG(20:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856229
alphaT3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.376119
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92658
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85382
DG(20:2(11Z,14Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70129
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50468
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22409
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07187
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221521
DG(24:1n9/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32473
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060032
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
DG(22:1n9/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21527
DG(20:3(5Z,8Z,11Z)/20:1(11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(22:1(13Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9868
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30171
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Effects of PIP2 hydrolysis	Reactome Pathways 2024	1.0	null
Exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.798096
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87667
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77889
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572418
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55083
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.158214
DG(20:5(5Z,8Z,11Z,14Z,17Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.67542
DG(18:1n7/0:0/22:5n6)	HMDB Metabolites of Enzymes	1.0	null
DG(20:1(11Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43773
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63785
DG(14:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
bronchial disease	GWASdb SNP-Disease Associations	1.0	0.685245
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151612_4_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45228
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5256
PPFIA2	Pathway Commons Protein-Protein Interactions	1.0	null
rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307167
colon muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
Actin filament	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
DG(20:3(8Z,11Z,14Z)/18:3(6Z,9Z,12Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94831
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1869
tracheal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03346
parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548517
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP3R1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2665-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06818
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43403
DG(18:0/16:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9431
DG(18:1n7/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50467
RKN	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.1141
DG(18:1n7/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.12433
DG(20:1(11Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:3(8Z,11Z,14Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:2(9Z,12Z)/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
DG(22:0/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(22:1(13Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.573616
DG(24:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.396732
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
bone marrow cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069108
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9588
RINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93879
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90213
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DG(22:4n6/0:0/18:4n3)	HMDB Metabolites of Enzymes	1.0	null
DG(16:1(9Z)/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CRCGN014_HEPG2_3H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0508
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DG(20:3(5Z,8Z,11Z)/22:4(7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CPNE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60217
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
DG(22:4(7Z,10Z,13Z,16Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
PPP3CA	Pathway Commons Protein-Protein Interactions	1.0	null
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
TNNT3	Pathway Commons Protein-Protein Interactions	1.0	null
DG(22:1(13Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
hsa-miR-224	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-substrate junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
DG(22:1(13Z)/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1536
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2395
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12786
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
IRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95357
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.425726
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66563
DG(14:1(9Z)/14:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(16:0/0:0/22:0)	HMDB Metabolites of Enzymes	1.0	null
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
amiloride	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
ITPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38482
DG(20:5n3/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DG(22:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204593
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG(18:1n9/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14736
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.308743
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.558285
DG(18:0/20:3(8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DG(18:1n9/0:0/20:1n9)	HMDB Metabolites of Enzymes	1.0	null
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
DG(22:0/22:5(4Z,7Z,10Z,13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06716
LMNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52991
DG(24:0/0:0/20:3n6)	HMDB Metabolites of Enzymes	1.0	null
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04615
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87476
DG(18:2(9Z,12Z)/24:1(15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:0/0:0/22:1n9)	HMDB Metabolites of Enzymes	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
U251	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45355
DG(18:3n6/0:0/22:2n6)	HMDB Metabolites of Enzymes	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
c-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.44347
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19516
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90708
DG(15:0/0:0/18:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/18:4(6Z,9Z,12Z,15Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8055-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07101
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71072
remains	GeneRIF Biological Term Annotations	1.0	null
DG(16:0/20:4(5Z,8Z,11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14538
MYL6B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50804
DG(16:0/0:0/14:1n5)	HMDB Metabolites of Enzymes	1.0	null
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295297
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43612
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.02608
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946671
myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.789796
PPARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
DG(20:2(11Z,14Z)/20:5(5Z,8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04082
CTCF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
DG(16:0/0:0/24:0)	HMDB Metabolites of Enzymes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56393
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61612
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894252
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.718292
HCC15	DepMap CRISPR Gene Dependency	1.0	4.34117
DG(22:1(13Z)/22:2(13Z,16Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133164
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5025
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.942
DG(16:0/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CAL62	DepMap CRISPR Gene Dependency	1.0	2.8747
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
ITPR3	Pathway Commons Protein-Protein Interactions	1.0	null
Tracheal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
DG(20:3(5Z,8Z,11Z)/20:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(18:3(9Z,12Z,15Z)/24:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32875
DG(20:1(11Z)/16:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
Craniotubular dysplasia Ikegawa type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
propofol-3048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0732
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69093
DG(15:0/0:0/20:4n6)	HMDB Metabolites of Enzymes	1.0	null
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36319
DG(18:4(6Z,9Z,12Z,15Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78928
DG(14:1(9Z)/20:4(8Z,11Z,14Z,17Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50471
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8449
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.3314
DG(24:0/22:1(13Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.02746
DG(22:2n6/0:0/22:6n3)	HMDB Metabolites of Enzymes	1.0	null
DG(22:2(13Z,16Z)/20:3(5Z,8Z,11Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33098
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00591
DG(20:4(8Z,11Z,14Z,17Z)/18:0/0:0)	HMDB Metabolites of Enzymes	1.0	null
DG(20:4(5Z,8Z,11Z,14Z)/20:2(11Z,14Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
DG(24:0/18:1(9Z)/0:0)	HMDB Metabolites of Enzymes	1.0	null
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
Calcium	HMDB Metabolites of Enzymes	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.733984