association	dataset	threshold value	standardized value
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6742
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38412
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
BRD-K16331797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03842
BRD-K83108629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20597
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Childhood type dermatomyositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52113
BRD-K47445962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2054
CCF-STTG1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85703
Autoimmune disease of exocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.03
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K49721311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06841
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2077
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
BRD-K46162352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07828
BRD-K09146396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93634
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63402
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72078
BRD-K30795375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0058
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61488
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91953
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68223
BRD-K34343777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01716
Alopecia areata	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44454
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09642
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12517
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2719
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44038
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22648
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14719
BRD-K17885598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27576
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24324
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48653
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40598
BRD-A85231803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34996
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60266
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0161
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
BRD-K36539857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33399
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2612
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06348
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1253
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5182
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33497
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10535
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11040405-jamanetwopen-e247974-s001.pdf-17-PRDM6_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
Central nervous system vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
Lupus nephritis in systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11212
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
BRD-K46609723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43012
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-K65824451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67929
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33315
BRD-K21866464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49431
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5575
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18072
BRD-K62957665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3026
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35047
Nephrosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1996
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14761
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47171
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26489
BRD-K50716325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.536
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20655
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CAMK2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87096
BRD-K96778009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21347
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14215
BRD-K63468420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34321
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14478
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.703
BRD-K50140257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24397
BRD-K90749965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22112
Adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
Benign secondary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7438
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1866
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5764
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00182
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1962
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36818
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5555
BRD-K39961819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43821
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.435
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24703
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5003
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66065
BRD-K96560179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35571
BRD-K10705624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6689
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05451
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49438
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32881384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.96288
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24545
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05755
BRD-A28219573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28209
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36636
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54063
Bone mineral density (spine)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1922
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18233
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
ARPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2777
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84458
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.794
BRD-K23868551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67135
BRD-A60877539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12878
BRD-K93624320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15337
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Graves' disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
BRD-K11679888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37515
Temporal arteritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
B-cell lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.708
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
BRD-K26431593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64848
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6334
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74125
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30698
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48397
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62807
RAB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0103
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20774
BRD-K48777375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37942
BRD-A43575461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11418
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7804
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7909
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4663
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02086
BRD-K63859730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18713
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15531
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05428
BRD-K14166090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19045
GSE124177_1_v_0_gonadotropins_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21088
Squamous cell lung carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
BRD-K60127720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24973
BRD-K80467627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98956
CRCGN015_MCF10A.WT.HP_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04517
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27599706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07077
Ankylosing spondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4205
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03516
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88553
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92348
BRD-K62309791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37146
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69841
BRD-K09366011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51256
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
Juvenile rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.4
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32646
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.014
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89921
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07756
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0249
Sjogren's syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.03
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04152
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09456
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K42849858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03342
BRD-K26863838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07262
BRD-K44483161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43641
BRD-K80290360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32422
BRD-K35625946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05668
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0259
non-Hodgkin lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.708
BRD-A55025683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40319
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.887
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5382
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3859
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19727
Hypogonadotropic hypogonadism 14 with or without anosmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36891
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13934
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.699
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6826
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69691
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.05299
Hepatitis B vaccine response	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.85229
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05645
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0174
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20995
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K02093145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.518
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8113
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49105
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29308
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5877
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.976
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32388
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53383
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22118
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0196
BRD-K69350885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15973
BRD-K48634117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88998
BRD-K91279674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47989
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88263
BRD-K88720906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66221
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68465
Granuloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59466
Type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
BRD-K57026098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23174
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03125
SETD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19552
BRD-K22380421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23691
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26999
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52956
BRD-K75620843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47972
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90823
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67454
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45781
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73539
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30828
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71906
BRD-K92374432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.423
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04962
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kawasaki disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.21549
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41055
BRD-K58118393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36739
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5361
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
A body shape index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
BRD-K08476323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27231
BRD-K53127464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64635
Atopic dermatitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8301
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76831
BRD-K76125116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51786
PMC12184553-JAH3-14-e039451-s001.pdf-14-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.041
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20651
BRD-K60932633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46323
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54815
BRD-K78818514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77542
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6483
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47388
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Itch intensity from mosquito bite adjusted by bite size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7031
BRD-K43915000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3956
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1536
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15473
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.992
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39052
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63262
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42031
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97885
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16441
Chronic lymphocytic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91944762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22545
Sarcoidosis (Lofgren's syndrome vs non-Lofgren's syndrome)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.3
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58665
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6729
C8orf33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53003
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92725
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2958
BRD-K73475697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13525
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4591
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27536
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93043
Stratum germinativum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23435
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16837
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.4301
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4821
BRD-K46293468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02159
BRD-K66708851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14696
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86475
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87015
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7882
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77809
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.124
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04635
Coronary artery calcification	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20225
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0137
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0989
Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.43979
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67747
Allergic contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.949
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3411
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57861
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23566
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15808
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
BRD-K41307363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02642
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4891
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59602
BRD-K42016545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50007
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34049
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4752
Paracentral lobule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.308
BRD-K69987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17668
BRD-K79829201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94837
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74322
BRD-K34335352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91982
BRD-K18600476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16486
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.67935
BRD-K49745983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12307
BRD-K05444553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16896
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06273
BRD-K22701871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91646
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1254
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09903
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65505
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18736
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09215
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1699
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.9462
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03995
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4212
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2744
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11555
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08571
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92735
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63244
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05492
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01346
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05521
BRD-K41662297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28068
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83855
BRD-K59708864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03609
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72055
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01539
PMC3348545-NIHMS263168-supplement-3.pdf-3-PBX2_PBX2	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1891
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82086
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72041
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97604
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3037
BRD-K81537454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31671
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01836
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63364
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73957
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.112
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06331
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0871
BRD-K95537020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01468
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18292
Hodgkin's lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3783
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05071
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.829
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0847
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39056
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1255
BRD-K11027431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7993
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0126
BRD-K73261251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56034
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
Hemoglobin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.5
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.2007
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22993
BRD-K72194126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22968
BRD-K80176886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.884
Benign renovascular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04708
BRD-K79352289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38944
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3807
BRD-K24499562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47257
BRD-K81006490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77856
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.5465
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11802
BRD-K18645499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62263
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20337
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29326
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41322
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28066
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28307
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21139
BRD-K82056353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41721
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00381
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4688
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53779
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27034
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03471
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14359
BRD-K57972271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89572
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73153
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10842
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02564
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17041
PMC11518656-ADHM-13-0-s002.pdf-38-SATB1_SATB1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0094
BRD-K12929741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13368
BRD-K72146456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.092
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0477
Autoimmune disease of the nervous system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9108
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80057
BRD-K53224568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50137
BRD-K22691925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86959
BRD-K88087295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28416
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4575
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.746
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52924
Mixed cellularity Hodgkin lymphoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14954
BRD-A42433574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54046
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2944
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81285
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15955
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
Waist-to-hip ratio adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
Periodontitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
Reticulocyte fraction of red cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.12218
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13693
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06571
Lactate dehydrogenase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.30458
BRD-K14082333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43995
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60271
ERMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00845
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.041
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.496
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05641
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8382
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08699
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.69625
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4781
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66683
Metachromatic leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
ATAD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13807
Vitiligo	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00969
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47938
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65723
Lung cancer in ever smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9269
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23956
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7339
Takayasu arteritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
Type 1 diabetes (age at diagnosis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48191
C1GALT1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45002
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22744
BRD-K90019187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15288
Vestibulum vaginae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42652
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14031
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56798
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6433
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5987
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9776
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
BRD-K96979108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51101
BRD-K00591281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05552
Autoimmune disease of cardiovascular system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29537
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20701
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03812
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.12372
BRD-K21936026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44087
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
BRD-K05051664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28139
BRD-K91516693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0938
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1862
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3214
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
BRD-K01894374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53053
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52572
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.47872
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
Response to hepatitis B vaccine	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.709691
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01983
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22628
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63543
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1424
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68033
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23766
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3252
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.4671
BRD-K34360192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30823
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12214
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26726
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27252
BRD-A05823365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57212
Collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3963
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.20129
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32704
BRD-K79619334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.074
Waist circumference adjusted for body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23973
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26527
BRD-K01360791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.96124
BRD-K85110576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.41021
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.3921
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4254
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72912
BRD-K69854611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51148
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57359
BRD-K86988191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03197
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3505
BRD-K38189757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44394
Lymphadenitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69124
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.88722
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50113
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38618
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6197
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40156
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03851
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
Kawasaki disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Hepatitis B	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.699
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
BRD-K45894579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35211
BRD-K54622858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22725
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.10485
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
BRD-K11117868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32019
BRD-K20847739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57704
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19284
RNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29921
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9151
BRD-K41141507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20306
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08135
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.818
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.78062
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39598
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00283
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55225
BRD-K06152379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06298
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
BRD-K93457574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44796
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38574
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51797
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.08521
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90087
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1984
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8456
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.75229
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1989
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.34375
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.992
CRCGN017_MCF10A.TP53.M_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0364
Connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15832
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13046
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61361
BRD-K12702054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06321
Prostate cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
Primary biliary cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.992
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18278
Celiac disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.795
Diastolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.6699
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.992
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70795
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4551
BRD-K21433749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44504
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00181
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3271
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1752
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07239
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87815
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31655
Primary immunodeficiency disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K91712163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82315
BRD-K24382357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57757
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01189
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.063
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53272
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8071
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4181
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00184
cefprozil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37291
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8425
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.15229
BRD-K30799912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55078
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66483
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2328
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26886
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04301
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.041
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60788
Myositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
BRD-A67697194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11587
BRD-K51608228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57693
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85132
SNRPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28187
BRD-K05050615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59249
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7647
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83066
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12321
BRD-K11585900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12502
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02045
BRD-K77150932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01921
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12291
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.594
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67195
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.025
Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
BRD-K24333636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08509
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34817
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81281
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51721
BRD-K55160246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02143
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09074
BRD-K82735282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83552
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.665
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.009
GSE140997_2_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76706127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76705
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64946
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43686
Inner ear disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
BRD-K43692189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24759
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14313
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3308
BRD-K53703060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31337
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.84371
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0816
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99596
Dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.949
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11124
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05833
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45031
Psoriatic arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
BRD-K09388706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20442
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7694
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8607
BRD-A45349889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28129
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75567
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99012
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61648
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00358
BRD-K83393282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35918
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
Fibrinogen levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46781
Activated partial thromboplastin time	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
BRD-K11516621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30058
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
Viral infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.699
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05902
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19989
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1096
BRD-K14719962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33271
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.25
Lung cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.75229
MHC class I protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9693
BRD-K51399866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17887
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33282
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
Myopathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
Proteinuria	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
CRCGN014_HEPG2_3H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02264
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96031
dr9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
BRD-K94196749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11798
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72045
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90379
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20278
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04619
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96523
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Muscular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12348
BRD-K29328556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31205
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22504
Primary progressive aphasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Y-linked spermatogenic failure 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6379
BRD-K58113140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05525
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
BRD-K60886324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61469
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2771
nucleus	GO Cellular Component Annotations 2025	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21238
BRD-K00882360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75418
BRD-K90808566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3659
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2452
BRD-K97576000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83059
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06586
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36584
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22169
TE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86363
BRD-K70315531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90917
BRD-K57270624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21641
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
BRD-K19672435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.19115
BRD-K32185628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38597
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
ls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28301
BRD-K85475457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55967
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4444
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19589
b19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7113
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9366
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
BRD-K72175798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46694
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3475
BRD-K26263099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0434
BRD-K46560430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09537
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Reticulocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.05229
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84239
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4148
BRD-K51160592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61139
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14347
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5245
BRD-K62758843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06638
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12717
Dermatomyositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
BRD-A26583774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21412
BRD-K44086628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02511
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
deferoxamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31148
BRD-K81281620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17721
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1418
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5233
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8472
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8911
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07888
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25447
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0626
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6652
BRD-K96671994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54464
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
BRD-K61020385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24924
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40547
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31867
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0696
Chronic obstructive pulmonary disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
BRD-K43982279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08843
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5392
BRD-K35259368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36832
ISYNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02969
BRD-A24369193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93085
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63573
Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.68508
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4648
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87265
3-CPMT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53795
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2989
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.544
furazolidone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16609
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68307
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27854
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25288
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08373
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34289
BRD-K84775364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02841
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.784
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.2144
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57063
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30689
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19985
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.949
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10273
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45263
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37467
BRD-A12166214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44228
BRD-K61909412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09151
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48028
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19353
BRD-K68330990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51412
BRD-K08618283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51968
BRD-K44713204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32709
BRD-K80880605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46374
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06267
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86348
BRD-K74663731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44553
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03268
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8071
Vitiligo	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.797
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4261
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65796
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83457
TIPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45584
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5066
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07843
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4669
BRD-K76691746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.10823
BRD-K90806964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79513
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26907
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15248
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02362
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.894
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.87794
BRD-K05940224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37939
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.53044
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0859
Hyperthyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.112
BRD-K84478344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.11317
BRD-K33236055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15323
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11594
BRD-K36884445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29496
BRD-K34761198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.29828
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10341
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8898
BRD-K34069025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40276
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6182
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91629
fh17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98586
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04678
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
Immune system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.7591
BRD-K95666495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35825
BRD-K47228832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4008
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61469
Membranous glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.041
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31901
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53915
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0565
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01562
BRD-K68939871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57613
BRD-K66538269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08116
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17154
BRD-K16966765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04711
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63231
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51359
Loneliness (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3959
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27302
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31311
BRD-K12099407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87929
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5379
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.986
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
methyl-salicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48251
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07687
Alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15624
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02287
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11841
BRD-K87541124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51133
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8548
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11621
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38697
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29688
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31431
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21766
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.78
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.792
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.976
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7681
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56134
Periodontal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0751
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01665
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.01255
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36404
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07484899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11617
Marginal zone lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.708
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00262
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04139
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49211
BRD-K92804652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37692
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.443
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17599
BRD-K75311902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19147
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25206
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9243
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11508
BRD-K18958510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90213
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.44
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
BRD-K86288396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25352
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.435
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34743
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3851
BRD-K21819164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32437
BRD-K94833531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28695
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36056
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
CRCGN011_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.54085
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90451
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7863
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83898111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93943
Rosacea symptom severity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
496100481_PCx_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39485
Mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1101
BRD-K04980212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19822
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18768
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55832
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15022
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1469
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49925
Autoimmune disease of central nervous system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
amidopyrine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70875
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85442
BRD-K70941976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6243
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7098
BRD-K27881453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8953
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24766
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0281
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49805
Nephrotic syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.23
BRD-K59518944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57305
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2848
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08791
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5489
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0046
BRD-K26786741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12769
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53846
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73889
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67251
BRD-K85234739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14741
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9576
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17905
Lymphocyte count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.85229
Psoriasis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25937
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82807
BRD-K34232791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16731
Sensorineural hearing loss	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3621
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6876
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.729
496100509_HIP_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5446
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11829
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69222
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19271
BRD-K11010670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29519
BRD-K75514760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01248
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19399
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
BRD-K59491389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85278
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12761
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47909
BRD-K68202226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07527
BRD-K80950551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01267
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.03753
BRD-K25177502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32842
BRD-K21036759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56324
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30663
Primary biliary cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30829
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27972
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45328
BRD-K93337444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21559
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1513
Auditory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.973
BRD-K65564503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86648
Autoimmune disease of musculoskeletal system	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05234
Visceral fat	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
BRD-K14364923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2578
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02055
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47742
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60065
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82697
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35984
BRD-K30963311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45009
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4885
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30709
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0793
BRD-K90311252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23044
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.053
Hepatitis C induced liver cirrhosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3066
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02788
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8704
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24998
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15293
BRD-K30910725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12063
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21399
IgA glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.956
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2343
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48844
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16909
BRD-K91022335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56516
BRD-K41563239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94652
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2329
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.797
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2302
Atopic dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.949
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82755
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72634
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85442
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44948
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48458
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1353
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.1626
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9833
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47615
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12166
BRD-K86938753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10681
BRD-K31536290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14683
BRD-K56890200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13279
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.976
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36441
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58991
BRD-K01512588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45824
BRD-K95895516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22935
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Lung adenocarcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.776
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.591
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1332
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1338
BRD-K35909757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9455
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1603
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31776
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02079
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_15_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06209
URM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27163
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.455
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80588
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27527
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8745
Multiple sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
PPIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16585
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
Contact dermatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.949
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25095
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8559
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38208
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14803
BRD-K32960568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56242
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.99765
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9167
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.02185
BRD-K97921950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01085
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
BRD-K52669647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82369
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.957
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
interleukin-12 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
BRD-K36099605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.81317
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.61549
BRD-K57205873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13856
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51478
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.035
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4741
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.041
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.45544
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45346
NUF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59424
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02142
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.065
BRD-K73880067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25232
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01217
BRD-K92009052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55793
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7094
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39124
Osteoarthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.214
CRCGN016_MCF10A.TP53.M_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07981
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35994
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0699
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33629
Muscle tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.968
Coronary heart disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41798
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01919
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2345
Pulvinar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
BRD-K04005364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06155
BRD-K52973286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48824
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autoimmune disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24888
BRD-K84054400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12099
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13207
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.733
BRD-K97938633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32428
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69933
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93564
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61544
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.81485
BRD-K24743998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72449
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22053
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13903
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50052
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.468