association	dataset	threshold value	standardized value
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58317
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28128
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6542
Peritrophic membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64227
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59432
hsa-miR-4329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71364
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
P granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KP2	DepMap CRISPR Gene Dependency	1.0	2.34623
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.84265
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12367
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10664
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59145
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81174
PSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00797
BRD-A17741195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37207
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03916
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18267
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
BRD-A26343863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89095
Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6891
TO175T	CCLE Cell Line Gene Expression Profiles	1.0	1.78676
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4355
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44223
SLR26	CCLE Cell Line Gene Expression Profiles	1.0	2.31675
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10233
A498	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15226
SK-N-SH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13448
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29468
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13005
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7077
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.348
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68366
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46177
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.6653
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15317
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12367
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725579
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6437
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4024
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39267
BRD-K98723391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11774
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25003
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19473
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70457
BRD-K19474742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59328
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50201
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49984
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88748
TOR4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69423
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996528
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K59851511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.586
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4139
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.99615
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NMB	DepMap CRISPR Gene Dependency	1.0	16.9803
Perturb_9459_KO_Srsf3_SRP143519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.68777
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.72037
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12335
LOVO	CCLE Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MU-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3304
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69181
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97246
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12904
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90885
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5036
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12993
BRD-A37645929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00722
protein serine/threonine kinase activity	GO Molecular Function Annotations 2015	1.0	null
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K98088240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05727
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50765
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10051
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	3.67187
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A818-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36776
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SREBF2	ChEA Transcription Factor Targets	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35523
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10681
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83696
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Hermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1052
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74121
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27208
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886682
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.71395
KASUMI1	CCLE Cell Line Gene Expression Profiles	1.0	1.45756
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22968
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EOMES	ChEA Transcription Factor Targets	1.0	null
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38339
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bursa copulatrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14907
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01443
CERITINIB	DGIdb Drug Targets 2026	1.0	1.35723
TMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3159
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05935
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05098
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02152
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912254
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11143
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12653
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1206
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14227
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38035
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57444
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.863133
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23853
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1193
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3869
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8706
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02525
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33851
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32912
Bmi-1_KD_GDS2724_102_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4424	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12395
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8172
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943151
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57215
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.45334
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1608
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27954
BRWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67141
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87364
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22089
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70528
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997957
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33733
BRD-K96778009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55857
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97481
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.015
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34974
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57782
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48009
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47794
BRD-K34095226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15141
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89505
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.378
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
PMC5515402__F3	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.00689
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0461
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
BRD-K97617600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95474
Ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1605
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10039
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02616
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25466
SPDEF_01_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61141
BRD-K87277021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16368
Lung squamous cell carcinoma_LUSC_TCGA-21-5786-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K50045741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03341
Stiff skin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
Perturb_1214_KO_Zfp580/Zbtb7a/Klf16_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.92381
BRD-K69854611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67496
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NALM1	CCLE Cell Line Gene Mutation Profiles	1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826894
SCML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50818
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186078
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100498_PCx_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09945
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5373-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69824
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.04735
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3913
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58838
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87093
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81036
BRD-K68300789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66506
Middle silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06062
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07255
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975145
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07599
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
Cnidoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64091
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03472
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25681
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894996
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60867
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15566
BRD-A84867566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03475
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50799
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65824
protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0474
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.87307
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.086
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00106
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2818
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05588
Lung adenocarcinoma_LUAD_TCGA-50-5936-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73059
Noonan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
BRD-K94744294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14566
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858931
srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.60271
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	1.37359
EW8	DepMap CRISPR Gene Dependency	1.0	5.49664
BRD-K41396351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1082
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.924956
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.055
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04559
COMPOUND 20 [PMID: 30998356]	DGIdb Drug Targets 2026	1.0	0.653481
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CD-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09871
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88209
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75886
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38801
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54743
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895592
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A847-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-567	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15089
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7934
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
butylated-hydroxytoluene	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69376
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81573
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61582
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22485
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07135
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
PACADD188	DepMap CRISPR Gene Dependency	1.0	3.22709
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993744
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90235
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052817
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
BRD-K67533212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17353
BRD-K48195969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05704
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54916
BRD-K87947740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33336
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8334
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90885
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1287
HCC1954	CCLE Cell Line Gene Mutation Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75174
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K72700187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45891
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Rectum adenocarcinoma_READ_TCGA-DC-6158-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16036
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0778
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70937
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02382
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
mantle zone of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35117
GP2D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49585
motile cilium	GO Cellular Component Annotations 2025	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053841
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS604T	CCLE Cell Line Gene Expression Profiles	1.0	1.85352
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SNMC-0826-SM-4DM66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04307
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15585
BRD-K63987422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07335
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.59463
BRD-K61407677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48852
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.05367
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5077-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4745-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5319
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52994
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15973
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06297
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08206
BRD-K96076719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48347
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08106
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00984
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840056
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3717
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
BRD-K76336129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15161
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946785
BRD-K84790105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44507
GW843682X	DGIdb Drug Targets 2026	1.0	0.150803
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35355
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
cell development	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28455914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87944
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12442
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854987
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93826
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33011
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32097
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65048
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01598
Lung adenocarcinoma_LUAD_TCGA-67-6217-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87479423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18363
Lung adenocarcinoma_LUAD_TCGA-50-5049-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.486
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4956
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.55082
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	2.44487
protein serine/threonine kinase activity	GO Molecular Function Annotations 2025	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18401
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5534
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
UOK101	DepMap CRISPR Gene Dependency	1.0	3.15424
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0184
BRD-K08000110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39765
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16904
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81994
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6272
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17058
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91488
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95186
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnesium ion binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K32021110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50749
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.49556
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27284
PMC12629863-CAC2-45-1547-s002.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Kinases_predicted_to_phosphorylat_YY1_at_Ser247_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29817
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98641
OSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13754
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53837
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
molecular_function	GO Molecular Function Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1392
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
MRPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5755
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55323
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34264024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0078
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83132
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3501
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6517-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.52129
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88142
Brain Lower Grade Glioma_LGG_TCGA-TM-A84T-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48676303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69695
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73666
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32693
BRD-K89277562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00999
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65048
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11974
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75007
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3927
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.729
Serine/threonine/dual specificity protein kinase, catalytic  domain	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A50913845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14443
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
Protein kinase-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18742
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899849
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89654
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6981
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15605
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20599
CCK81	CCLE Cell Line Gene Mutation Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5236
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37498
Lung adenocarcinoma_LUAD_TCGA-64-5775-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38607769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08874
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72177
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K69471644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79814
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35731
hsa-miR-522	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11423
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50458
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17998
primates	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06341
CLPP_KO_GDS4791_104_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH2228	CCLE Cell Line Gene CNV Profiles	1.0	1.38576
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93988
Protein kinase domain	InterPro Predicted Protein Domain Annotations	1.0	null
negative regulation of TOR signaling	GO Biological Process Annotations 2023	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22138
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887825
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54583
HCE4	DepMap CRISPR Gene Dependency	1.0	3.58286
metabolic process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17074
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0577
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5268
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85705
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980492
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.453
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
Perturb_17298_KO_Ptbp2_SRP071653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.72489
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48962
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91189798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75501
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03916
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84426
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941124
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26085
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74698
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.41492
E2F6	ENCODE Transcription Factor Targets	1.0	null
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
secretory granule	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54946
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03933
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867156
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857825
BRD-A14098586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31862
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11948
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.4526
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.193
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
BRD-K25638876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1132
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04231
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853616
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.125
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051143
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3966
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942705
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01202
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36908
A1207	CCLE Cell Line Gene Expression Profiles	1.0	1.62468
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07539
BRD-K17582293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32307
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44828
BRD-K04367224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34772
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.25279
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4924
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
cellular response to glucose starvation	GO Biological Process Annotations 2023	1.0	null
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62905
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30484
multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
Perturb_3390_KO_Utx_SRP242086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.38877
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18183
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936216
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9622
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
19808870-ST1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882772
BRD-K06392309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78245
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.6074
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.71
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14263
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87779
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28244
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5193
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1926
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06479
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1647
BRD-K94273044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21156
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43612
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36521
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
BRD-K34377350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03665
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16056
Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10482
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13952
protein phosphorylation	GO Biological Process Annotations 2023	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5439
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4313
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953767
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28139
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DOVITINIB	DGIdb Drug Targets 2026	1.0	0.06463
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7622
SNAI2_01_292	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59268
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05433
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
single-organism process	GO Biological Process Annotations 2015	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38801
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
BRD-K96560179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20695
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870109
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36624
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
magnesium ion binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95057
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11793
BRD-K85216683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65271
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17556
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56519
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7782
Chronic Graft-Versus-Host Disease	DisGeNET Gene-Disease Associations	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76244
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A64Z-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29657
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.827873
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63982
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2786
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndromic X-linked intellectual disability Cabezas type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
CAL72	DepMap CRISPR Gene Dependency	1.0	3.85388
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6525
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21351
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
transferase activity, transferring phosphorus-containing groups	GO Molecular Function Annotations 2015	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07822
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.85992
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4659a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Primary ciliary dyskinesia 19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4201
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9545
developmental process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221004_1_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058337
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47255
HCT15	CCLE Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58719
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875867
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5819
UM-SCC-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3703
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K02093145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03505
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66348
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22573
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80892
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75E-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02077
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79277
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4025
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862123
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50629
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85724
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1689
BRD-K83122599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11441
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13721
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939142
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88265
BRD-K82433264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4906
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52404
ATP binding	GO Molecular Function Annotations 2023	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61145
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62569
HSC4	DepMap CRISPR Gene Dependency	1.0	2.37898
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
U2904	DepMap CRISPR Gene Dependency	1.0	3.79495
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24326
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47642
AM38	DepMap CRISPR Gene Dependency	1.0	2.02992
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25037
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10139
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899849
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923553
FAHD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.029
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13473
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0435
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08531
HCT15	CCLE Cell Line Gene Expression Profiles	1.0	1.93885
BRD-K43558307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13257
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04658
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41114
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70434
piP-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8053
organelle	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5852-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36278
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92987
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28204
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
adenyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32773
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0264
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
negative regulation of intracellular signal transduction	GO Biological Process Annotations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.32133
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K00804254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35205
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039839
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41537
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80103
TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08401
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.597
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05054
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89445
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05702
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0421
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.64607
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.94231
SNU489	CCLE Cell Line Gene CNV Profiles	1.0	1.50434
Mesothelioma_MESO_TCGA-LK-A4O2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37604
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82165
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834109
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18598
regulation of TOR signaling	GO Biological Process Annotations 2023	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18713
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19G-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34215
Magnesium	HMDB Metabolites of Enzymes	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sperm connecting piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.537
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-mouse_kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.54534
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1771
protein modification process	GO Biological Process Annotations 2025	1.0	null
5637	CCLE Cell Line Gene Mutation Profiles	1.0	null
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.963
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.968414
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37900095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01656
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40057
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54096
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01548
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48229
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64496
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84442
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.925
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72347
Cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72359187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70294
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15457
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94321
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15249
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1878
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853508
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48705
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73168
496100629_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06437
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4845
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05318
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.93976
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9112
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24979
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.657764
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09073
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35355
BRD-K00950228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23271
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
report	GeneRIF Biological Term Annotations	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	7.30231
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41604
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.88188
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87354
Brain Lower Grade Glioma_LGG_TCGA-RY-A83X-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73839552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81327
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48516
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90199
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04595
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10896
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1197
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978886
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960613
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19283
GSK3A_knockdown_201_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.79826
MEWO	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K05475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03244
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
PMC5770158-elife-31706-supp3.xls-ISL1_target_regions-Nearest_gene_2_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4162-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t30-blood-rna_female_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-5.06131
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KYSE520	CCLE Cell Line Gene Expression Profiles	1.0	1.68695
cellular response to starvation	GO Biological Process Annotations 2023	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.9192
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47282
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09808
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36025
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
sperm part	GO Cellular Component Annotations 2015	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9729
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
NCIH1792	CCLE Cell Line Gene Expression Profiles	1.0	1.48769
cellular process involved in reproduction in multicellular organism	GO Biological Process Annotations 2015	1.0	null
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4135
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6837
Prostate adenocarcinoma_PRAD_TCGA-EJ-7321-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
C1orf56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67029
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.126
TT	CCLE Cell Line Gene Mutation Profiles	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
BCL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92327
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06484
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02806
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77631
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974361
IQSEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63768
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925178
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HT-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02224
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959428
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32578
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K98251998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51385
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.433
SETDB1	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6471-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60558
ZNF705D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79553
BRD-K92891227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38771
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59936
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03633
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21081
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31605
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57161
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47925
Germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69152679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75254
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
NVP-TAE684	DGIdb Drug Targets 2026	1.0	0.0571003
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.262
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82731
CENISERTIB	DGIdb Drug Targets 2026	1.0	0.051142
motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K56868780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88411
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28633
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30719
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2514
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93894
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81097
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96836
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989703
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60112
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22138
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6272
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.45985
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4158
BRD-K52713598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47165
PKMYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56874
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.34683
colo857	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
hsa-miR-4676-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835371
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11208
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95722
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1004
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76113
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25564
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76406
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86941
BRD-K04980212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51591
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55895
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01512
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.873
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A53850583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52457
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1304	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6665
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11651
SEC24A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87207
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3067
HS742T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93129
BRD-K15863674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10151
Myosin XII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01197
signal transduction	GO Biological Process Annotations 2015	1.0	null
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24802
BRD-K77024507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08593
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3358
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01023
BRD-K95788660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09673
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06756
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62516
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8711
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K21997380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13613
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926532
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18463
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Chromatoid body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.153
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00028
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62965
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5563
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FU-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940479
PPARG	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.41743
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
phosphorylation	GO Biological Process Annotations 2023	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32245
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08462
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02713
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.899
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0058
BRD-K21472066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83246
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02564
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100524_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21732
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.60732
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2833
acrosomal vesicle	GO Cellular Component Annotations 2015	1.0	null
GSK3B_knockdown_202_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83591
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46177
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.848
BRD-K08300592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25181
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15438
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950318
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
Graft-Vs-Host Disease	DisGeNET Gene-Disease Associations	1.0	null
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
BRD-A20242387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2419
BRD-K19085288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64401
BRD-K04791118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22382
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99222
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858203
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29376
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93952
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.12993
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924286
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96832
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39517
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851273
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20909
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03046
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889465
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K72437469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11721
BRD-K75583553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0234
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4514
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16427
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38304
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52657
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07741
hsa-miR-3675-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17765
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23319
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH2887	DepMap CRISPR Gene Dependency	1.0	3.8795
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.082
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.62582
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50009
HT115	CCLE Cell Line Gene Mutation Profiles	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.48733
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43887
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K43782839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91209
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9739
SNU1040	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Kidney Chromophobe_KICH_TCGA-KM-8440-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.83182
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32026
TAMATINIB	DGIdb Drug Targets 2026	1.0	0.072609
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35356
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.071
Endostyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
BRD-K16940345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69512
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
RERFLCSQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05682
KLF15_KO_GDS4780_419_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
COL18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27437
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15688
Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
CLPP_KO_GSE40207_388_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POU5F1_01_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60831
PWWP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62611
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931669
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-214-AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18184
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05262
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5408
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15581
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35947
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41738
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43042
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1726
HPAFII	CCLE Cell Line Gene Expression Profiles	1.0	1.49496
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01156
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06569
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14483
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04246
Lung adenocarcinoma_LUAD_TCGA-55-8511-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K90060707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02795
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69796
Limited scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38032
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
GSE62974_1_v_0_epas1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K18402224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19002
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51035
L428	DepMap CRISPR Gene Dependency	1.0	2.46998
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23807
BRD-K05277255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17233
LS180	CCLE Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06654
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.527
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548o	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992046
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17805
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20418
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.42488
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74336
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24074
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30452
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MS-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01879
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82248
MAPK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61472
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRDM16-22522345-PALATE_MESENCHYMAL-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34383
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12657
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
BRD-A85231803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30372
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71082
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9469
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28128
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53529
BRD-K92460921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13346
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39338
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06175
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31978
col7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59368
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89666
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
Gut juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
BRD-K08618283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4522
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847661
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54163
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5302
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7386-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61095
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03791
Dyskinesia of esophagus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
intermediate stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03806
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9961
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
hsa-miR-3925-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15205
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976306
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26617
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7417
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61324
TGFBR2	KEA Substrates of Kinases	1.0	null
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52404
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50716325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44504
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1717
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5186
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.17523
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13809
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0894
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04124
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858974
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12976
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
SNU324	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70528
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07114
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01783
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38598
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07069
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36707
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.823
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90642
BRD-K83994491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12276
Tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88024
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34764
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829739
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38422
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14103
PCI15A	DepMap CRISPR Gene Dependency	1.0	3.36094
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933121
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16845_KO_Kcnj10_SRP241402	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55607
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K84517695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66497
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52748
TP63	ChEA Transcription Factor Targets	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.149
Lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
BRD-K24170552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02342
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.907526
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eosinophilia-myalgia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-8569-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS411	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K60661821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24905
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850763
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.827
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14107
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86513
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58149
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34882
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00344
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31336
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27554804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81972
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36339
CLDN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26915
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35496
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.40855
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12318
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193044
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857646
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46028
SETSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0208
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cilium	GO Cellular Component Annotations 2023	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I1-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24771
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13093
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929865
BRD-K05223209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04988
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97261
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
motile cilium	GO Cellular Component Annotations 2015	1.0	null
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27486
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58912
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58215
SH3D21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98034
Serine/threonine-protein kinase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.354
BRD-K06250424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06577
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85002
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.44362
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_1_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62445
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75806
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0029
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01261
BRD-K44298652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59851
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3692
BRD-K00046588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03667
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Biofilm matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.916
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857084
Acute Myeloid Leukemia_LAML_TCGA-AB-2963-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_FOXJ2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K77252933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38838
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45847
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82234
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
TBP	ChEA Transcription Factor Targets	1.0	null
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0685
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.808414
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11948
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8634-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65048
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07558
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24948
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09799
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.74154
BRD-K40738002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34452
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051012
ATP binding	GO Molecular Function Annotations 2025	1.0	null
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10737
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49455
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28682
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17253
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9824
SNU81	CCLE Cell Line Gene Mutation Profiles	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65086
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9344
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8039
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A12830281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08763
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53856
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06489
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5938
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19955
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1706
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855286
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.14225
BRD-K00363054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.139
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.206
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20937
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28997
tssk1b	GeneRIF Biological Term Annotations	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0948
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6456
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K25718133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33641
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95162
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17975
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2179
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85742
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899849
PF-562271	DGIdb Drug Targets 2026	1.0	0.0565513
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66326
BRD-K99116119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13857
BRD-K35491869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6278
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923768
BRD-K39705203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25795
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12777
ZDHHC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
CMLT1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.95152
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858203
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50696
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33591
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
AKT1_knockdown_135_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.83757
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28694
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4401
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96474
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01945
ZNF649	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17321
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91293
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30151
Perturb_16605_KO_Bend2_SRP357909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50139
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.747
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5071
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.54118
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39147
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14746
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77889
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13721
cilium	GO Cellular Component Annotations 2015	1.0	null
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34773
Protein kinase, ATP binding site	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4976-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64877
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3836
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.013
Lung squamous cell carcinoma_LUSC_TCGA-63-5128-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
R3HDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
BRD-K45508763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04388
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.10092
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01980291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21981
Inner acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
Brain Lower Grade Glioma_LGG_TCGA-CS-4941-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3144
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.61696
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31577
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69216
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.61975
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38323
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847115
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52597
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88275
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26718
3-CPMT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61105
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29639
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00938
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.7664
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53452
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958092
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44894536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69562
BRD-K39979171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04121
C2BBE1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65965
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79954
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5834-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.128
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.77929
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.988
HL60	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48239
RCHACV	CCLE Cell Line Gene Mutation Profiles	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48835
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878601
BRD-K46298074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9361
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.093
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39531
cell projection	GO Cellular Component Annotations 2015	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61209
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APH1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46543
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.40662
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4681
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11401
SOX2	ChEA Transcription Factor Targets	1.0	null
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94908
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7262
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960613
ZNF263	ENCODE Transcription Factor Targets	1.0	null
BRD-K58270905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83209
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847293
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07433
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.22895
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867647
Alveolar epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08742
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23998
BRD-K82935855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35352
Apical ectoplasmic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.755
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6868
NAGLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24471
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864259
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.66475
Autoimmune Diseases	CTD Gene-Disease Associations	1.0	2.88009
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8476
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02382
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54235
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60205
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43745
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3964
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66359
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20557
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.764
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37812
Sperm mitochondrial sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.522
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08244
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34312
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991465
NCI-H508	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36768
Anterior silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916124
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926115
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
evolution	GeneRIF Biological Term Annotations	1.0	null
127399	DepMap CRISPR Gene Dependency	1.0	2.83697
BRD-K43909206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75191
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994512
UPMD1	DepMap CRISPR Gene Dependency	1.0	2.17502
BRD-K19766710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26139
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
hsa-miR-520b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42928
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40649
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05433
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89505
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.58099
RPMI8226	DepMap CRISPR Gene Dependency	1.0	5.37176
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.25243
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879081
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23579
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18956
TGFBR1	Hub Proteins Protein-Protein Interactions	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20403
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6565
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46502
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0351
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31598
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995163
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34633
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9524
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0979
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60901
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16353
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.3069
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51317
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33355
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7090-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82032
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945812
BRD-K83307202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34241
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77448
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81938
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15522
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35386
TGFBR1	KEA Substrates of Kinases	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855507
testisspecific	GeneRIF Biological Term Annotations	1.0	null
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45217
SLR26	CCLE Cell Line Gene CNV Profiles	1.0	2.18742
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0351
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36347
EZH2	ENCODE Transcription Factor Targets	1.0	null
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19904
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.18944
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1077	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3505
Acute Myeloid Leukemia_LAML_TCGA-AB-2915-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2BBE1	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823986
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01571
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31722
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89767
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.93082
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2244
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22587
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95646
Embryonic germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0545
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2222
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919934
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02373
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17363
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38185
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91405
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31336
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15583
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
CRCGN014_HEPG2_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1743
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TGFBR1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82718
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923276
Male Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K51448234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73515
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59945
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13461
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM115	CCLE Cell Line Gene Mutation Profiles	1.0	null
SKRC31	CCLE Cell Line Gene CNV Profiles	1.0	1.53207
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058326
5637	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26085
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.72996
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877087
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73969
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLPP_KO_GSE40207_392_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08741
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96121
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12517
MNAT1_Deficiency - Ablation_GDS2561_689_mouse_Heart - 2 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868716
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57817
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27969
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.603
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20861
2313287	CCLE Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K64904523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92486
cilium	GO Cellular Component Annotations 2025	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPP_KO_GDS4791_537_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1866
IZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.174
hsa-miR-1538	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18854
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49172
protein modification process	GO Biological Process Annotations 2023	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20189
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38412
BRD-K47508820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47069
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29672
BRD-K69872823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3715
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.649
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960613
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.865
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104159
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88221
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26085
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.847838
CLPP_KO_GDS4791_374_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7351
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
hsa-miR-149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992288
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9476
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.39135
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K86998514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22383
BRD-K11625057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62754
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75526
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subiculum, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47162
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42831
hsa-miR-409-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
AZD4547	LINCS KinomeScan Kinase Inhibitor Targets	1.0	0.850157
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.69134
anion binding	GO Molecular Function Annotations 2015	1.0	null
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-mouse_kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KLF15_KO_GDS4780_509_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66846
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28275
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03455
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9559
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02166
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41983
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02238
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94401
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53632480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09091
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16035
bacterial-type flagellum hook	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.35555
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08418
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	1.0	1.49993
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886682
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21793
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1009
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
786O	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83668
ion binding	GO Molecular Function Annotations 2015	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5503-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7380-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62726
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36624
BRD-K31081052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13896
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1366
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958338
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00974
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
REST	ENCODE Transcription Factor Targets	1.0	null
BRD-K97138361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0749
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54203
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.566
hsa-miR-4731-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857624
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
Depression	DisGeNET Gene-Disease Associations	1.0	null
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4675
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981092
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64905
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33048
BRD-K20288742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04906
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
kinases	GeneRIF Biological Term Annotations	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77713
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319134
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35341
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04046
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22166
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65048
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23918
L-cysteine desulfurase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
VP229	DepMap CRISPR Gene Dependency	1.0	2.37291
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2395
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19881
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36735
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.25384
Lung adenocarcinoma_LUAD_TCGA-78-7542-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20865
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47107
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
BRD-K49529874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64639
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0606
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924286
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6228
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94434
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857524
Extrinsic allergic alveolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11525
HUG1N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57966
BRD-K32947579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11784
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08215
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16538
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19139070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12176
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86002
Silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
colo800	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
Subcutaneous tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
BRD-K87537204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21185
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2465
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899849
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50036
WM2664	CCLE Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59758
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28516
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07353
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6897-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26494
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11344
Kinesiophobia	DisGeNET Gene-Disease Associations	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.96133
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
BRD-K21036759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2229
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20611
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08467
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.20183
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21385
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72554
PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K02783902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12099
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07946
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.01263
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3365
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67251
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-520e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K82883803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18239
Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874624
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2412
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7009-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96396
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00926
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42499
Prostate adenocarcinoma_PRAD_TCGA-G9-6353-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17287
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1654
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45245
BRD-K74767736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22595
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72007
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915321
hsa-miR-4275	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09219
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HRT18	CCLE Cell Line Gene Mutation Profiles	1.0	null
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957916
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34232791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25638
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.538
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86625
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.073
BRD-K36493118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79037
BRD-K53221607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66398
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0232
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55516
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23155
BRD-A90969585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25972
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52736
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43919
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02166
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66912462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43867
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12899
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3131
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954881
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20459
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66197
Crystalline style	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39963
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7707
SNU182	DepMap CRISPR Gene Dependency	1.0	3.6423
bone marrow	HPA Tissue Protein Expression Profiles	1.0	2.00057
MFM-223 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.818796
BRD-K57226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26787
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Localized scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01293
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858203
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26805
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9168
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259591
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23057
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02642
hsa-miR-4738-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2555
BRD-A82976259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36079
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20539
pi-body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.639
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05493
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10267
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50471
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09666
BRD-A71001587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5325
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20043
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85437
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5914
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2476
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11232
BRD-K32485819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26844
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25283
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12371
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
SJRH30	CCLE Cell Line Gene Expression Profiles	1.0	2.89609
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0322
BRD-K61924304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2406
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84331
BRD-K25226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22351
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1929
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50534
BRD-K90962922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02129
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01387
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52162
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11144
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9703
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	0.857207
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01532
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20514
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857825
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875838
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7259
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34146
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859194
BRD-K65178566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41711
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.183
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44582
Forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47744
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73191
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15251
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896757
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
SW1573	CCLE Cell Line Gene CNV Profiles	1.0	1.56913
protein kinase activity	GO Molecular Function Annotations 2015	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45926
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50795
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24329
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.695
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5029
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02975
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
19962670-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.641841
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Diffuse scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
BRD-K02717912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16535
DOK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96344
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35432
BRD-K23430114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0524
prostate	GTEx Tissue Gene Expression Profiles	1.0	0.941143
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
reproductive process	GO Biological Process Annotations 2015	1.0	null
BRD-K31010207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41998
BRD-K94469522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48784
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6843
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
BRD-K80724972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35169
GSK1059615	LINCS KinomeScan Kinase Inhibitor Targets	1.0	1.19568
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
spermatid development	GO Biological Process Annotations 2025	1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59689
CLPP_KO_GDS4791_107_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72962
CHEK2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1957
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3565
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04698
UBB_KO_GDS3906_496_mouse_Testis -  28 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05564
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1651
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58396
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15322
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061277
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45139
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.57594
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.40507
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
protein serine/threonine kinase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K26634905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21102
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19422
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26613
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12575
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78715
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.691
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.50481
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.899849
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91705
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27879
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79655
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3773-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7563
Orbital area, ventrolateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70857
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82872
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15074
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14612
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57403
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954076
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29867
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0246
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11117
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.27238
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54489
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.2145
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31175
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8328
CLPP_KO_GSE40207_378_mouse_Testies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48703
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	2.02745
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.971552
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69677
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11842
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.49035
PMC5515402__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.793
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphorylation	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6514-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947968
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46812
BRD-K33953218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46662
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43041
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6003
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47822
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11336
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64141
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904219
hsa-miR-1288	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
DB	CCLE Cell Line Gene Expression Profiles	1.0	1.55066
hsa-miR-520c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3806
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28071
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08976
phosphotransferase activity, alcohol group as acceptor	GO Molecular Function Annotations 2015	1.0	null
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
spermatid development	GO Biological Process Annotations 2023	1.0	null
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68454
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5108
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.104
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Acute contagious conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06297
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2325
LN18	DepMap CRISPR Gene Dependency	1.0	3.94179
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31226
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
protein phosphorylation	GO Biological Process Annotations 2025	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967173
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.883
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70923
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32693
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98537
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97675
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0747
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02328
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76313
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.43553
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7832-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74789550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59103
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17248
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51416
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66909
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18763
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.42078
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69424
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10841
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4695_KD_Srsf3_SRP059321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19165
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K81370109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5104
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28865
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1651
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53516
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10813
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71848
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33419
CTCF	ENCODE Transcription Factor Targets	1.0	null
Telangiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12272
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80839
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81217
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69726
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	1.45708
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35011
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7229-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45398
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86653
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37673
GSE77569_0_v_1_bexarotene_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A115-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	1.0	1.34888
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868101
hsa-miR-155	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13721
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.67977
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69773
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9354
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.45351
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02437
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05042
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32111
atp binding	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02230174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20443
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
BRD-K28320832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31021
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102557
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
cefprozil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27671
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15649
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.87535
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850769
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77481
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.59566
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58285
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45693
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87624
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05454
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3516
BRD-K82637883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09041
HLE	CCLE Cell Line Gene CNV Profiles	1.0	1.34098
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997871
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04079
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886682
Posterior silk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0283
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
SLC6A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44948
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27418
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26085
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.54751
VCAP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.54846
DBH_KO_GSE33906_53_mouse_heart (E10.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A23434937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16588
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36416
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.831849
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52994
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87332
BRD-K33204113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31075
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	0.857207
BRD-K04650671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07511
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44298
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7605
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SYO1	DepMap CRISPR Gene Dependency	1.0	3.7684
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8214
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938736
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22048
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63149
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91453
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948713
NCI-H820	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGFBR2_KO_GDS5008_282_mouse_Embryonic palatal mesenchymal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07191
BRD-K96384208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11175
Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87632
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858203
BRD-K96778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28417
Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.80169
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913566
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5593
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22429
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29716
spermatid development	GO Biological Process Annotations 2015	1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
PRDM16	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12322
BRD-K97638135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2647
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06955
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46019
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33804
BRD-K37971917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25365
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57521
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35844
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45011
GTEX-XUZC-1226-SM-4BRVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934169
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60298
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6334
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09147
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34255
Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5026
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.508424
Velocardiofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
MYNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14695
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18481
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.61246
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
medial part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35027
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.974712
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13026
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54946
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954552
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
hsa-miR-4746-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
developmental process involved in reproduction	GO Biological Process Annotations 2015	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.86049
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968431
BRD-K52152765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17748
cell part	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2395
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26613
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10426
Myofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0782
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31459
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81215
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.98488
SNU407	CCLE Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61576
hsa-miR-4502	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80979
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K03035008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28743
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01734
Sessile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24763
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4659b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91033
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19674
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.858203
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2283
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80285
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6916
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47891
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051143
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12276
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.62846
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX1_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57262525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20225
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72208
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.02127
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2531
BRD-K90808566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20272
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5063
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
hsa-miR-639	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10369
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9824
BRD-K91962463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40884
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48875
phosphorylation	GO Biological Process Annotations 2025	1.0	null
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15663
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3028
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6555
TE9	CCLE Cell Line Gene Expression Profiles	1.0	2.56948
MORCPR	CCLE Cell Line Gene Mutation Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PD0332991	LINCS KinomeScan Kinase Inhibitor Targets	1.0	0.908676
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34312
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826523
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.16483
hsa-miR-4427	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7613
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K77144444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05725
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60901
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50229
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01033
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tssk2	GeneRIF Biological Term Annotations	1.0	null
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU620	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3516
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42548
PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960613
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.53855
TGFBR2	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60647
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16146
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37037
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5291
BRD-K79199168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13618
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62659610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32287
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66766
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01447
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6536
U2-type prespliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
BRD-K26272845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81185
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04134
KDM5A	ENCODE Transcription Factor Targets	1.0	null
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.05001
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
DBH_KO_GDS4324_362_mouse_Embryonic heart  E10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
BRD-K50177531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50402
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67265
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10432
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97775
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.755
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89838
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12343
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08182
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09884
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.874
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5183-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	2.05168
Nucleoplasmic periphery of the nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90799
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
adenyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.25795
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56179
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28853245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31082
Dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
BRI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44594
Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.75248
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35685
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
BRD-K56405136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12312
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.067
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80198
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891568
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.42858
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.18154
GSK269962A	DGIdb Drug Targets 2026	1.0	0.127855
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63045
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37898
BRD-K02839126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41037
BRD-K64055457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28337
BRD-K13803936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15531
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K70721203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64335
Large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35405
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A84941884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59439
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3639
germ cell development	GO Biological Process Annotations 2015	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37214
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903254
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887825
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11703
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
Nuclear envelope adjacent to nuclear pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76244
ABCA1_OE_GDS2303_189_mouse_LDL receptor-deficient livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K18562194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67546
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
NCIH2342	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73676
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.164
BRD-K85284710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0406
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988145
NOS1	DepMap CRISPR Gene Dependency	1.0	3.63013
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64268
BRD-K72721410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06842
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73039
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.093
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24763
PMC5006001-srep32069-s2.xls-Common_with_CREM-Genes_de-regulated_by_loss_of_CREM_and_Trf2_CREM	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15924535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35954
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09769
BRD-K01512588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00774
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
FLYWCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98809
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24123
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21587
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62215
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
HDAC6	ENCODE Transcription Factor Targets	1.0	null
mRNA cleavage stimulating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88368
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0175
NCIH82	DepMap CRISPR Gene Dependency	1.0	9.77944
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
Perturb_8015_KD_Crebl2_SRP214573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35784
magnesium ion binding	GO Molecular Function Annotations 2015	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95733
ricinine-6067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATM_Deficiency_GDS1544_769_mouse_Lymph nodes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35926
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74386
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96804
BL1165 (TRIM24)	NURSA Protein Complexes	1.0	null
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68324
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71082
BRD-K04462989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37206
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4867
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.45791
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7557
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81176
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51506
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835838
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958101
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4963
CRCGN017_MCF10A.TP53.M_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10685
BRD-K56427898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58648
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.66836
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8017
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58345
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5937
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845268
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32325
RCM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19972
BRD-K33967077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44719
BRD-K43449580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33541
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189538
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12368
biological regulation	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12178
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74395
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Desmoid tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6148
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95527
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
BRD-K87465930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00684
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K30600059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45306
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15495
BRD-K47467075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51392
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.968
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7612
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94476572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97275
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927416
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31969
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87422
Lung adenocarcinoma_LUAD_TCGA-55-8505-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.78423
LOUNH91	CCLE Cell Line Gene CNV Profiles	1.0	1.45625
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57822
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33043
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03957
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908836
A375SKINCJ1	DepMap CRISPR Gene Dependency	1.0	3.17421
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03683
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82674
Acute Myeloid Leukemia_LAML_TCGA-AB-2870-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1206	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17171
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40296
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80911
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88Q-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7668
BRD-K63354944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16526
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00656
BRD-K51181201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60454
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95574
GSE240386,GSE242143_8_v_3_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.102
BRD-K21356734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32393
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K36me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01422
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04957
kinase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15896
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08425
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1301
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07358
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1866
BRD-K39087168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2997
Perturb_10438_Mut_Adad2_SRP262140	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.47367
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27956
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40929
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3863
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4622
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29232
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846111
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53822
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836135
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12083
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35388
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986262
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
496100486_PCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63692
BRD-K70052888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10136
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950111
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10553
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31165
BRD-K64404450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85047
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4984
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38801
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01351
BRD-K26734305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26204
EN	CCLE Cell Line Gene Mutation Profiles	1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61645
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K94258680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24689
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18887
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865216
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22988
protein binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309697
hsa-miR-575	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26071
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34169
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04577
CORL105	DepMap CRISPR Gene Dependency	1.0	5.59561
KARPAS422	DepMap CRISPR Gene Dependency	1.0	2.78217
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40501
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05755
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
Calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.11046
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73532
PSMD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59942
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935546
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-342-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04404
BRD-K99172965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00966
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49782
hsa-miR-3161	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2684
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE228413_2_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57904
BRD-K71452126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06012
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910262
BRD-A67697194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53956
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.44211
NCIH2347	CCLE Cell Line Gene CNV Profiles	1.0	1.57745
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832596
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01517
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95206
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
motile cilium	GO Cellular Component Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133213_10_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58792
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A86F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83925
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27278
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22229548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5083
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36937
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36984
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88367
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196599
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0399
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43388
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44125
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01756
BRD-K13472433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50193
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.99617