association	dataset	threshold value	standardized value
GSE158815_1_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053808
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00435
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09478
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.241854
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08568
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16362
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.133
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17106
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39338
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2451
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054783
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30108
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45436
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33172
GSE132433,GSE132436_1_v_0_nr2f2_human	RummaGEO Gene Perturbation Signatures	1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923813
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17561
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_132_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07828
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23536
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38344
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05795
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864365
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
Mitotic spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43707
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67429
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	426.162
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
9+2 motile cilium	GO Cellular Component Annotations 2023	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38018
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33382
SET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8673
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.53751
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050162
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06154
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06765
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.11066
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96009
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10468
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74303
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042466
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0916
Perturb_6228_KO_Mbnl1/Mbnl2_SRP142522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.69294
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14241
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23047
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6346
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7634
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE201454_1_v_2_ftcd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.988128
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38297
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31191
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57228
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2915
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.759
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36326
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36775
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33791
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82749
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
MOB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89679
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04284
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911209
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15321
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47053
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92349
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05911
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23579
protein-glycine ligase activity, initiating	GO Molecular Function Annotations 2025	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03501
C1QL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21239
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
TMX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4983
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.669
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35947
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33262
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69046
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11933
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92286
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1161
Aster	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32958
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90281
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37357
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02233
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17819
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94064
MEG-01	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.845
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861253
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.167
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25832
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945532
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51862
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06337
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36448
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42229
all	GWASdb SNP-Phenotype Associations	1.0	0.030753
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03153
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81097
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44278
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	173.5
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87254
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06016
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74055
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.2123
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84148
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79468
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.238
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12258
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14621
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852648
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25549
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.2669
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050943
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70704
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45142
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43878
PCDHB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55891
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	280.466
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905912
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
SAFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86909
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41659
Metabolism of proteins	Reactome Pathways 2024	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81634
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.03378
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.43562
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.826
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00645
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920535
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.742
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8345
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80889
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64663
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75877
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76092
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8969
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61758
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65257
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENSG00000230707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36834
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043289
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22196
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04911
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54529
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30159
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10379
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68704
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99606
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61593
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43612
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14003
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67957
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EPHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40773
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18745
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
lateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02671
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843065
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05224
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
CDYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2766
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10608
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.040735
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58798
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08353
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78483
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23053
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80027
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15588
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46454
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26606
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84167
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.601861
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60832
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860267
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46936
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65235
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00016
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	370.697
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.314
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
JMJD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.301
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26004
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03755
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890871
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946924
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56454
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.997
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.51871
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26382
GDF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28767
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43138
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0684
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.249
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15502
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.338
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15535
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248874_1_v_0_pcdh9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60759
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054857
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50877
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24817
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983291
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4994
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cilium	GO Cellular Component Annotations 2023	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13786_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.85657
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17906
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	284.877
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87325
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30541
cilium movement	GO Biological Process Annotations 2023	1.0	null
GSE212628_2_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.88937
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4828-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958277
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17644
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sebaceous gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.238
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32548
CREM	ChEA Transcription Factor Targets	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056927
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19328
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932089
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25611
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50245
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9123
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.12847
SIG-M5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15213
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
CNFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04028
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1114
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10087
Perturb_13785_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.61369
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29797
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93311
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.832194
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.40017
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.2039
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910473
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G3-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1142
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34775
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.836892
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-8568-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5110-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06271
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00435
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7421
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952633
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948841
SAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78905
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49255
COLO-680N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.0839
NCI-H929	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47568
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.727
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28211
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
CTCF	ENCODE Transcription Factor Targets	1.0	null
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15386
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
BL73 (CLSPN)	NURSA Protein Complexes	1.0	null
LZTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9566
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47873
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57571
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60597
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15173
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15779
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85553
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17743
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.07049
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958277
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827518
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46881
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68904
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29472
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.488
mRNA_NR0B1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61454
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54344
CHD2	ENCODE Transcription Factor Targets	1.0	null
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08874
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92374
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947482
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02151
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40428
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03539
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10468
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1936
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	393.961
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08501
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975888
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.99354
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68064
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	172.248
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.337
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17808
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	266.634
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55513
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02269
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
mRNA_STAT3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peptidyl-glutamic acid modification	GO Biological Process Annotations 2023	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.709
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49822
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9655
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827511
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959239
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30048
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.631
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10266
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
PHF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96225
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52728
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256925
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70806
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09485
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853003
RAD21	ENCODE Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4419
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89388
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40465
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.19921
vascular disease	GWASdb SNP-Disease Associations	1.0	0.072045
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21852
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6103
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63251
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34597
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aril	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935827
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941504
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08478
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.067487
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZY-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
ciliary part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.004469
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.9068
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8022
cell lysate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539396
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0809
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27605
Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23718
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3529
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74077
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01111
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.35987
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.86116
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01937
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76003
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25563
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04368
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52831
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57461
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37493
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28408
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89866
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.91019
MSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07834
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24929
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46488
NPRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3863
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11417
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22347
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.677
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Bacterial Infection_Leukocyte - Monocyte - Macrophage (MMHCC)_GSE6435	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.24955
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
Choreaacanthocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50386
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27282
POLR1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3381
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08082
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23464
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03125
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59469
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74855
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58361
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2211
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48875
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22412
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cilium assembly	GO Biological Process Annotations 2023	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90449
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08879
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082594
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73824
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52606
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.785
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52635
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49672
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08082
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20802
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35285
MYC	ChEA Transcription Factor Targets	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17484
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8231
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09783
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933974
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2211
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03643
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23047
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82097
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	198.98
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36451
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PBXIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02043
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9965
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21035
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CLIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00898
C15orf61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95299
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.04958
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11761
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10294
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10717
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46467
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07081
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188599_11_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21003
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.84039
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17109
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
stroke	GWASdb SNP-Phenotype Associations	1.0	0.511281
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70082
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06905
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44853
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11038
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824023
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17871
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20563
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33094
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99606
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36918
POFUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.994
DRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67438
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.697
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12511
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.94828
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76176
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51999
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19096
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4861
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31828
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.076426
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10070455-41598_2023_32568_MOESM3_ESM.xlsx-Genes_AA-genes_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2752
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05711
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IMR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.609691
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51326
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85501
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
H19_DEPLETION_GDS4787_92_mouse_C2C12 myoblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76506
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81466
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1059
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34892
HEP_3B2_1-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65284
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26156
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0609
SUZ12	ChEA Transcription Factor Targets	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041428
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2626
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42775
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00435
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41822
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
PLS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050789
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.112
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44391
Perturb_11289_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.49335
Peptic ulcer disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.847
MYL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53356
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02476
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12022
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02242
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
NB6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001592
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5473
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75582
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33323
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03021
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62679
TENT4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46958
ventral endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01054
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18977
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19352
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.308
PPARG	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51T-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7336
SLC30A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61338
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94756
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0284
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05108
Tubulinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76253
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.634586
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14335
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8527
Acne	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.238
MAFK	ENCODE Transcription Factor Targets	1.0	null
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3767
PMC7450273-mmc2.xlsx-ST12-Unnamed_4_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2615
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32768
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0624
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59063
YIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98854
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04954
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85668
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86016
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99134
IZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37779
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35876
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26905
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26446
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15352
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46802
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.3211
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046813
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5566
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52831
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61365
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21068
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vesicular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88418
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.2142
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963828
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914177
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.277
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842565
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832641
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54801
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042708
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26123
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22153
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36967
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.056
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31721
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911209
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947482
sperm flagellum	GO Cellular Component Annotations 2023	1.0	null
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08907
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59519
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13787_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.84385
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.067615
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041693
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL1052 (N4BP2)	NURSA Protein Complexes	1.0	null
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19571
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.703
protein-glycine ligase activity, initiating	GO Molecular Function Annotations 2023	1.0	null
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48694
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29852
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26854
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_11_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24316
MZT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.2386
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67125
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08986
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858327
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35563
SIK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52137
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36707
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18374
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00811
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867378
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptidyl-glutamic acid modification	GO Biological Process Annotations 2025	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.309
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05019
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922297
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886098
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19421
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52478
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34137
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04954
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08593
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40432
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891598
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980586
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55687
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43623
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2553
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.354042
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.946
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4579
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1035
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22697
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18878
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05911
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30804
Perturb_15071_OE_Fezf2_SRP041818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60166
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52683
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.837
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36326
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934172
Kidney Chromophobe_KICH_TCGA-KL-8339-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94159
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041676
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08852
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957332
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2325
artery disease	GWASdb SNP-Disease Associations	1.0	0.100901
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19421
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
Stroke	dbGAP Gene-Trait Associations	1.0	0.021644
ASH2L	ChEA Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.458
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22908
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2222
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49745
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5468
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33034
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17743
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86836
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59342
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90195
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15456
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02545
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56582
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Post-translational protein modification	Reactome Pathways 2024	1.0	null
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15227
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33499
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86186
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25933
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50854
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74623
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07732
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65533
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45223
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38235
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260202
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63819
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15089
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00265
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13806
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	325.987
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93462
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65235
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00366
GSE180951_6_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864365
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.825216
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63575
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88888
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.52002
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15662
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87332
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01365
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBC691 (GTPBP2)	NURSA Protein Complexes	1.0	null
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910473
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05472
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2662
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0904
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55599
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71382
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.04338
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056726
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.0651
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX3	ChEA Transcription Factor Targets	1.0	null
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94019
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75395
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69147
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QZ-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47916
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01001
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90281
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94116
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36897
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08822
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38692
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10302
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32948
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4071
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31443
ZNF761	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22225
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.44281
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.881314
GNPDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57553
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24245
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27206
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33139
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13612
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31643
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.8469
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36453
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70747
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83334
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20339
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.284
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7913
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.48358
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10289
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.075595
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966987
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4701-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4656
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BI-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5423
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7542
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24921
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47568
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.58235
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71769
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910473
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24654
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14734
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
MAP7D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88292
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17696
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45801
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56923
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8602
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32152
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042029
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00044
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	204.604
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.508
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18642
CROCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85634
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922297
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.016
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.11483
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7738
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5978
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
FOXRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00843
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2208
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94733
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68883
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24532
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21621
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02729
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00455
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06346
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40601
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	165.797
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08852
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81913
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78572
SPG21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05892
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.8279
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26279
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD51B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82938
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50584
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11904
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1334
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38457
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55952
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02448
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0401
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.745
EFNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7265
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93305
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
intermediate stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28529
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17689
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.4747
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59349
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51244
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80219
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1148
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.917385
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68355
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.9211
ENDOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33253
cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.052222
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30351
WDR54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3319
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9375
SRD5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0587
organelle assembly	GO Biological Process Annotations 2023	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9992
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Precatalytic spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.238
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5862
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.22646
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H69	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05703
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73823
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87516
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39215
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.57353
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01723
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13937
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.69
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811056
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84378
MUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63333
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7913
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.125363
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051585
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0595
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26068
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22942
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	150.616
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35148
tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.680284
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49616
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04704
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840911
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23944
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32913
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23004
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4416
Brain Lower Grade Glioma_LGG_TCGA-DB-A64R-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10075
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.589
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3485
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14343
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00488
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.7
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
STAT3	ChEA Transcription Factor Targets	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864365
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60368
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890354
REST	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7875-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50386
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07885
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
Duodenal ulcer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.847
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48197
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887293
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.742
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1208
Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94585
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2617
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23907
cilium assembly	GO Biological Process Annotations 2025	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5202
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
protein polyglycylation	GO Biological Process Annotations 2023	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69415
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627485
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34634
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85716
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57889
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.605284
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0272
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65187
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876389
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
PPP1R2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.663
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
FBXL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03132
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832102
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39699
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
Perturb_11298_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9208
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83918
SIDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25938
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53441
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29834
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827719
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71965
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.698
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49822
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65882
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7050-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81917
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56494
NKX2-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.33991
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11741
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904525
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.083986
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21659
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ependymal cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
NUMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33373
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84351
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20563
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046319
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04883
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24175
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6024-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65235
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07546
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99363
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0624
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21852
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RC-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958277
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35704
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0395
SYNGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57479
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42581
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98595
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886422
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3637
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03212
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70137
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
TM2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5064
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14969
Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79092
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07053
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45842
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99354
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0318
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11761
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36459
Perturb_13779_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.3389
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00638
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88854
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935708
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83565
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30827
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36058
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882456
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.825497
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04026
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68102
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08822
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39901
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15662
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.210615
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1081
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02899
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37838
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.641
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869277
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6804
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13784_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.01661
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34683
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9265
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
KPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56879
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.34577
cilium	GO Cellular Component Annotations 2025	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.26229
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07811
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862031
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68152
MYOG	ENCODE Transcription Factor Targets	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82879
ELOVL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15086
NR1I2	ChEA Transcription Factor Targets	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68416
LZTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83518
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18491
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.990436
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89058
Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	275.491
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1466
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4803
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887084
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056902
NPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50886
mRNA_SMAD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030799
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axoneme assembly	GO Biological Process Annotations 2025	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.46123
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28074
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.797
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01502
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47915
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54882
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92316
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866548
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.083
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40138
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6508
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4476
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27556
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43521
SYNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86415
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
Polycystic kidney disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39795
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43216
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29693
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28535
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947482
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
kidney disease	GWASdb SNP-Disease Associations	1.0	0.937304
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050789
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34848
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043287
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60842
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54407
SMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1784
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09854
disease	GWASdb SNP-Disease Associations	1.0	0.028221
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71893
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00082
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51549
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02957
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.1062
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.385
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37493
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30199
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16875
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74452
Prostate adenocarcinoma_PRAD_TCGA-G9-7522-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59543
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07602
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92844
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35833
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.39843
LMO2	ChEA Transcription Factor Targets	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00373
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08856
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981551
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042333
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7855
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
SC-28748 (TGFB1I1)	NURSA Protein Complexes	1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14903
POLR2A	ENCODE Transcription Factor Targets	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35763
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30935
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01167
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51722
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.40719
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62493
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903465
Perturb_8637_KO_Arid1a_SRP312002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.22884
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29704
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7105
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08762
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19558
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15474
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50391
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55192
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864365
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35035
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53545
microtubule bundle formation	GO Biological Process Annotations 2025	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.059
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67064
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19625
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67376
DERL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79353
Carboxyterminal post-translational modifications of tubulin	Reactome Pathways 2024	1.0	null
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
cilium organization	GO Biological Process Annotations 2023	1.0	null
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38542
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46802
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.99211
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pick body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04741
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94833
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22142
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02269
BL1000 (FANCI)	NURSA Protein Complexes	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04883
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	106.203
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60868
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81079
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73204
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83465
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29797
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8237
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57853
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36864
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11315
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09498
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80115
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68C-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein polyglycylation	GO Biological Process Annotations 2025	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46427
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07053
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80283
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null