association	dataset	threshold value	standardized value
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
Branch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53822
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03173
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18873
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847663
piperidolate-3551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18109
BRD-K26647686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23469
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20029
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15151
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7711
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73129
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06935
HEPACAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00471783
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.88321
Micropyle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
5255229-949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.013
Mesocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43548664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57345
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7355
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.576
Storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22891
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917401
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
Reduced Visual Acuity	DisGeNET Gene-Phenotype Associations	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
YWHAQ	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43686
tetracycline-6233	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.119
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866686
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381343
amoxicillin-6285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
BRD-K27221973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72833
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960125
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29P-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04007
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.88606
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6593
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sulforafan	CTD Gene-Chemical Interactions	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79492
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
BRD-K49391713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11146
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46445
BRD-K61414850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33634
Kabuki Make-Up Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BRD-K45904306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01737
trifluoperazine-2389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05409106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71953
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5645
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
h4ii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24318
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.543
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
BRD-K86716312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10611
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21268
f1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880699
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35281
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01993
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
mepenzolate bromide-3748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K59701963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44943
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842154
BRD-K43324262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09416
sirolimus-1162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
84br	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46755
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19028
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gap junction	KEGG Pathways 2026	1.0	null
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
BRD-K94469522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69265
cefaclor-2843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41241300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61021
Polar microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
LM-1685-207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990681
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
PTPRS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679115
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1846
Perturb_9137_KD_HMGB2_SRP106038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.46814
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77979
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257841
Colorectaladenocarcinoma	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.934135
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05494
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04717
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880841
EPHX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534635
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40129
Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50924315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46856
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7083
BRD-K38607769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63139
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K59130783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43937
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67365
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51898
Photosystem II reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
AR-A014418-7070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18473
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
BRD-K67597437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39447
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15225
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39635
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46274
CRAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57458
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
Chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lymphosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
MAP3K7	Hub Proteins Protein-Protein Interactions	1.0	null
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869093
SCCOHT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
DBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34007
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874279
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904224
Parkin-Ubiquitin Proteasomal System pathway(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13596
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03964
T24	BioGPS Cell Line Gene Expression Profiles	1.0	1.37469
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67618
Hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32896
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.3195
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2431
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11824
BRD-K75620843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31761
GSE143662_3_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00702
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920416
BRD-K53224741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11167
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
HNRNPL_02_160	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
BRD-K36168475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04136
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01728
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896482
METTL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52162
BRD-K05074020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09887
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16502
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinoid acid signaling-responsive fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
Parkinson disease	KEGG Pathways 2026	1.0	null
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13675
BRD-K86371068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49496
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92997
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01457
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75581
PMC11266089-Table3.XLSX-Fig1_Disease_targets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-1026-SM-4B64M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12435
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75381
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2103
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08145
Autosomal dominant distal hereditary motor neuronopathy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Superficial urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
nifedipine-1692	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845131
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30338
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859989
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHEMBL:CHEMBL1795737	DGIdb Drug Targets 2026	1.0	0.315071
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
clidinium bromide-4499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95556
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42211
fluphenazine-1662	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17399
BRD-K96604397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99216
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055928
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
urinary bladder	HPA Tissue Gene Expression Profiles	-1.0	-1.20111
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956094
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4339
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826818
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61137
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03426
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
benzocaine-4808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Magnetosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2718
glafenine-7018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
BRD-K04462989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76613
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18156
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NDUFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97147
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32764
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7351
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2835
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41022
BRD-K18070214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69941
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928228
Alzheimer 39 s disease	WikiPathways Pathways 2024	1.0	null
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34579
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02416
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6852
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04101
mianserin-6260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74867
BRD-K56241426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82534
PGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25147
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71472853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66645
H2AC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07012
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24955
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243886
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911879
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
L-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37738
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06446
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.522723
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201822
LY-294002-1652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alverine-2110	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80297
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00991
hsa-miR-4532	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Integral component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A459-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35165
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
UACC257	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.979831
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88728
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51573654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38206
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78328
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
Alzheimer 39 s disease and miRNA effects	WikiPathways Pathways 2024	1.0	null
MAP3K1	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K67526257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07564
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855132
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7075
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864077
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76809
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53662389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24201
Stigma papilla	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74122
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25239
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51563
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cotinine-2011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058836
BRD-K26809097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29343
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46541
PARN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72239
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25548
pivmecillinam-3535	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
N6-methyladenosine-5332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Leaf primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56233
isosorbide-6038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
SARS-CoV_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40739
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64018
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Stromule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
BRD-K62965224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12773
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
BRD-K80198069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87129
TT	CCLE Cell Line Gene CNV Profiles	1.0	2.75264
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0545
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099071
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854628
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.835321
ITPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46247
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20212
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
Female inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262754
BRD-K95922469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05283
levocabastine-7009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K13803936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64943
PMC9084694__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27075
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15322
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0598
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65725
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64328
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52541
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22594
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830497
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898454
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
COX7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25989
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8404
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5207
BRD-K06399794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63292
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Mesothelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76851
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31981
resveratrol-5509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bad5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62064
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24541
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854803
cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.37966
BRD-K19662956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85115
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23042
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16264
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962196
Chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
BRD-K40621788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28298
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09236
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11089
CBLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00399581
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27104
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.49
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43058
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051102
desipramine-3212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
S-propranolol-3523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70613
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32812
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.754
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42962
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18185
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98905
17850661-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961203
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43114
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22337
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
Keratoconus 9	DisGeNET Gene-Disease Associations	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.17234
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14153
larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
SNU449	CCLE Cell Line Gene CNV Profiles	1.0	1.66687
HECTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89456
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40311
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K18558473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48148
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18125
IARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73886
cefsulodin-4148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterior adductor muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
tRNA (m7G46) methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
tamoxifen_homo sapiens_gpl8300_gds3604	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32214
DL-thiorphan-6249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acetylsalicylic acid-4428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
LHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89184
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44491
BRD-K71554049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70683
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1706
nf96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	1.63028
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40643
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23016
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92423
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-860-3378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25548
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03879
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46393
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07148
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17529
BRD-K55780532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29945
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25593
LASP1NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80581
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.18747
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71075
5151277-903	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
solasodine-4305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PKR	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27085
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14436
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trifluridine-3559	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K34363290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03887
isoxicam-7268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24136
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826401
Pulmonary sclerosing hemangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
HERC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19643
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827879
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50076
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
GPAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30707
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71931
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866686
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
tyloxapol-4611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isocorydine-2780	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
Cestode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	1.91845
sc93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
MAP3K3	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K62794454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49914
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
IKBKE	Hub Proteins Protein-Protein Interactions	1.0	null
pathogenic escherichia coli infection epec	KEGG Pathways	1.0	null
opm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_up-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40131
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35264
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.20111
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.952332
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
NEC8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91539
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891225
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03769
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90915
H-7-5941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06828
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40374
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36414
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055676
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.952953
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18748
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85914
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clorgiline-5005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19028
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66997
Tubulin/FtsZ, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
Thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40073
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06038
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16303
Pt-K2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01646
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27705
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957873
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40022
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24409
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
NFYB	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848274
BRD-K73780763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46188
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
nalbuphine-2063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2023	CCLE Cell Line Gene CNV Profiles	1.0	1.34117
fluphenazine-4461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22293
adrenosterone-5464	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92702
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22201
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62269
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52317
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13373
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252787
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866686
BRD-K58112932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03867
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991806
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
Egg chorion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
CP-944629-7549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1047
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95196
BRD-K13888422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.22347
DRAXIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67953
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327915
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02939
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323533
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.192
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58254
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14667
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53624
MUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63333
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	1.82989
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Amyotrophic lateral sclerosis	KEGG Pathways 2026	1.0	null
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.896
BRD-K88964321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21738
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K69471644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55012
Aster	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
416B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K92776249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77753
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998723
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64461
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Mitotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5798
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00292
wortmannin-977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71119
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Perturb_15370_KD_TP53_SRP294453	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998221
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NFKB2	Hub Proteins Protein-Protein Interactions	1.0	null
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26051
BRD-K37019305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08751
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01568
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934387
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08439
BRD-K22595044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0305
Pathways of neurodegeneration - multiple diseases	KEGG Pathways 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11718
Xcp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.4855
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22865
bucladesine-3483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49242
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40704
BRD-K63068307_ZSTK-474_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NT2-Rho0 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26365
LIN7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22085
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3956
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84923
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250788
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39468
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85384
PMC4792926-ncomms10810-s3.xlsx-list3_G9a_PHF20-overlaps-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94669
BRD-K42034238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97258
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513497
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.81385
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
phenformin-4283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85093
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17901
LIPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54963
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.958186
Skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9249
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93469
ANAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20518
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33066
BRD-K49878220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02722
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244723
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16347
BRD-K96898856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00836
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
miconazole-4960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02344
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6815
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4571
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46736
Spitzenkorper	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22541
BRD-K17395396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25455
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045036
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51507
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10195
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4016
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32301
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30217
RSL24D1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525412
2q21 1 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82703
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37208
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5026
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87201
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
non-growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47153
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31869
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21549
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2945
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57551
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63562
EIF4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00793738
betulin-3513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
iopanoic acid-3527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acetazolamide-1686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971434
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90382
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70707
Prestwick-691-2813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nipecotic acid-6500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K55144248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71482
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74251
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52631
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830936
Autosomal dominant distal hereditary motor neuronopathy 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
CYRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49589
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hemocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
SRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04179
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92848
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53329
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86379
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03378
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18122
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01444
BRD-K57096799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41444
BRD-K82145108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33746
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963165
TMA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31861
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.54475
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59504
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
JB-89-SI60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236545
microtubule	GO Cellular Component Annotations 2023	1.0	null
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44267
cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.305515
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
Brain Lower Grade Glioma_LGG_TCGA-DB-A64L-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85926
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55457
BRD-K58268854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18241
BRD-A77292814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16226
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47185
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51217
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937545
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMC18	CCLE Cell Line Gene CNV Profiles	1.0	1.6775
BIN-67 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
AKAP8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15527
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96989
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dropropizine-7429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367129
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
pentetrazol-2092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06433
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38809
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Delta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.2
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6853
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.65
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03174
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.38576
CHUK	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51713
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0529
vanoxerine-1625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08714
BRD-K28354175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05665
Polar nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46424
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289353
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26934
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81654
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918953
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32603
BRD-K96627018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72609
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
UPK3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
moracizine-3520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
riluzole-4689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IKBKG	Hub Proteins Protein-Protein Interactions	1.0	null
morantel-7010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90731
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
chse214	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05011
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06935
Hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15185
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868905
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6542
JL1	CCLE Cell Line Gene CNV Profiles	1.0	1.86979
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06028
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06935
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51147
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16721
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
17177833-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1036
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932618
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02137
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28285
Corneal fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904761
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23182
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85705
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
BRD-K35544244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04517
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2197
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55379
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81391
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63888
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A21584932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3252
ASK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71251
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997106
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.936368
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48366
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
PMC5130036-oncotarget-07-40690-s006.csv--AR_signature_for_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56921
naloxone-5243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02494
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920275
BRD-K50081142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06818
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Photosystem	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
BRD-K48835953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32026
BRD-K81370109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21792
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18471
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88869
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cellular bud neck septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18905
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866654
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.8118
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.44263
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926739
nabumetone-6327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
shikonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68216
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64845
ketanserin-1593	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
etifenin-4117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gamma-tubulin small complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12487
EPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00382072
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
LY-294002-1664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estradiol-1021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11324
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06834
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24527
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75796
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40601
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32628
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4814
JHOM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32354
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936739
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSTO-211H cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
RPUSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5014
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39228
Thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
BRD-K25423830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20193
pirenzepine-5872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28593
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19469
chlorhexidine-2025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884417
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
GPATCH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86556
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07057
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955011
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09119
JHOC5	CCLE Cell Line Gene CNV Profiles	1.0	1.63469
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37285
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23321
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2784
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44615
SK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
BRD-K12312755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19822
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54464
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
(+)-chelidonine-5760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K76508844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.92297
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
azaperone-5877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
BRD-A26343863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94118
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65753
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75373
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60062
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948554
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07658
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
Chloroplast ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825371
mesoridazine-7256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41853443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6702
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88576
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0771
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13302
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	0.829961
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91656
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48157
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91962463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42738
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
Byssus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917601
PMC7880901-NIHMS1649581-supplement-2.xlsx-DESeq_V7_1_and_3_vs_Ctrl_1to2_f-Table_S1_List_of_AR-V7-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
BRD-K44626845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03872
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
diprophylline-1689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
domperidone-4640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.42626
Macular degeneration_Fibroblast_GSE1719	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.00949
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Polymeric cytoskeletal fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.46
Human immunodeficiency virus type 1 group M subtype B (isolate MN)	Virus MINT Protein-Virus Interactions	1.0	null
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17384
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.315105
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
NFKB1	Hub Proteins Protein-Protein Interactions	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879052
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40045948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22074
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965758
BRD-A82976259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05924
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.11442
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.15295
tanespimycin-947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAP3K14	Hub Proteins Protein-Protein Interactions	1.0	null
PF-00562151-00-6907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
19861896-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XXEK-2426-SM-4BRUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054193
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07168
AA-68-OJ16_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284438
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.594454
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91739
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6362
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10995
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
tretinoin-6170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01835
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
diclofenamide-5286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229839
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19773
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
BRD-K74096348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13663
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65296
ketorolac-7286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bromovanin	CTD Gene-Chemical Interactions	1.0	null
IFNAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454379
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
carbamazepine-5518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oxaprozin-971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K41207293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14399
bromocriptine-1925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
PMC11399026-tau-13-08-1472-supplementary.pdf-1-MYB_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
zidovudine-5333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32223
ifenprodil-5463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17092
pararosaniline-893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94597513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01427
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.972493
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043331
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28536
troglitazone-1657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839188
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30913
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30318008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23689
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921516
BRD-K50075939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31038
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
Leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.794
PMC4792926-ncomms10810-s3.xlsx-list_2_PHF20-dependent_E2_genes-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42476
C5orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12092
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68747
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1032
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5213
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
TNFRSF1B	Hub Proteins Protein-Protein Interactions	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828966
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46694
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05538
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33136
Synergid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039983
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58551
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21365
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08875
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23058
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948554
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32598
BRD-K75148160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82198
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825479
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32621
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
BRD-K42032479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5903
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2382
Photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.316
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
GTEX-OHPK-0426-SM-3MJH3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850223
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46477
cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2708
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66762690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40453
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231482
BRD-K22800340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23671
BA-95-YU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227973
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29244
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88272
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
Osteoarthritis_Synovial Membrane_GSE1919	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.63346
GSE110802_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81461
cell cortex part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.321201
Autosomal dominant distal hereditary motor neuronopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Trolox C-7304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16679
risperidone-3508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02704
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70237
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77218
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.46851
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967406
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.46454
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
a95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893775
BRD-K06261202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4643
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K78813464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12922
mimosine-5302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITPR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067887
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48425
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235748
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.300533
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826829
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.32459
CGR-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4422
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pea10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52068
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
CAMKK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ABCD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453577
PPC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
BRD-K97452545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33738
Apoptosis	KEGG Pathways 2026	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32632
PMC8052288-mmc4.xlsx-PAF-DREAM-Lung_Poor_Survival-Unnamed_5_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.28251
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13624
BRD-K58876832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58869
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25621
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.473772
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93872
denatonium benzoate-6502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52875
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15628
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993445
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69147
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
mefexamide-2121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
4-hydroxyphenazone-1497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88437756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12947
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Prestwick-1084-6767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49208610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04035
Simian Acquired Immune Deficiency Syndrome_T lymphocyte_GSE4785	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.88063
KLRC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513966
T-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
BRD-K17107214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98524
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83046
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41928
todralazine-5512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABT-751	DGIdb Drug Targets 2026	1.0	0.296538
BRD-K46877890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21157
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60858
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973811
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28079
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52548
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
BRD-K01827055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18842
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06675
CD47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32753
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947958
penbutolol-3534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876789
BHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
BRD-K62833556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13424
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14739
alpha-estradiol-990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58192
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19889
SBC5	CCLE Cell Line Gene CNV Profiles	1.0	1.4916
Megasporocyte nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
azapropazone-3143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estradiol-5238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clemizole-3672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.887
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26742
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04813
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
5211181-950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pronetalol-2902	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26385
MIB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.229
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19711
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16972
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23382
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.254183
Plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
BRD-K38446773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06744
Lung adenocarcinoma_LUAD_TCGA-80-5607-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48358
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863376
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830711
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5178-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12813
FASLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6208
JURKAT E-6.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.703
92br	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988938
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
JB6 Cl41 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
KELLY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77566
BRD-K70052888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24193
MRPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25453
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61035
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28492
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57012
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19096
IA-97-VE31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230128
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16306
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease axonal type 2L	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
sulconazole-4998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0743
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985772
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
neostigmine bromide-5335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
prostate	GTEx Tissue Gene Expression Profiles	1.0	1.16272
Vitellarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25644
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1445
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
Larval cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34869
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0702
BRD-K50497551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1542
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.685
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66796
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23381
BRD-K93153656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19971
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28463
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02719
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49361
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827374
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73621
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00637
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27274
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44104
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03235
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.22
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65792
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53282
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHEMBL:CHEMBL2036119	DGIdb Drug Targets 2026	1.0	0.315071
BRD-K64173373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03329
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
BRD-K57262525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33989
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17596
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21776
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
urapidil-6696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239284
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84047
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46945
Irregular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08253
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259591
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
Holt-Oram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
F5 meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
rescinnamine-4386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Integral component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-1826-SM-3NB22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983162
TUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56784
20035825-TableS7a	GeneSigDB Published Gene Signatures	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05066
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13957
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03258
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896386
gap junction	KEGG Pathways	1.0	null
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55396
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44218
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1696
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40453
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845438
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16014
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86846
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73732
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44888
BRD-K92012390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0223
Fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.874107
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81987
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831328
f2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41701
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47744
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
SYVN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98884
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84778
griseofulvin-4687	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843669
GSE239768,GSE239769_1_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951678
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94386
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68758
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9941
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40592
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08027
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
BRD-K55638368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7879
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53353
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04701
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49362
BRD-K82504878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17441
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6289
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16532
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
Plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67255
guanyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26723
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
BRD-K43782839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18995
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04286
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06682
BRD-K46526566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72422
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
RPMI7951	CCLE Cell Line Gene CNV Profiles	1.0	1.52962
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68022
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81802
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18381
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01214
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10336
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32713
BRD-K02793474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95245
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51943
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4121
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889443
H3K36me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5528
BRD-K93126086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08721
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866686
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27949
RBM22_02_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.42626
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68331
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18925
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9491
valproic acid-1647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06445
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Serine C-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.417
BRD-K43610632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49455
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00266
diclofenac-5861	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930559
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04196
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12044
podophyllotoxin-5841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RELA	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77586
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50521
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K95822658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24832
BRD-K83966071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24636
BRD-K23075656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1205
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
TMEM191C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71508
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
bufexamac-5515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80658
BRD-A53850583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15867
Clouston syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961476
Aggresome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
atropine oxide-4476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86851
Hidrotic Ectodermal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
PMC4075250__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Prestwick-1085-3554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3426
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24196
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tail fin cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99797
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53885
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14791
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969153
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55267
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
praziquantel-5874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.32912
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6906
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825782
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
CL14	CCLE Cell Line Gene CNV Profiles	1.0	1.47521
norcyclobenzaprine-2830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1551
orphenadrine-4359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50718861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64015
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
Central vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73123
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
BRD-K69035249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0891
Tubulin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
C6/36 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857446
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K32021110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97458
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K93693615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33045
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837975
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1812
Motor proteins	KEGG Pathways 2026	1.0	null
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09221
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09981
BRD-A14803952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58561
20208059-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.768
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
dapsone-5498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25259
GTEX-O5YW-1526-SM-3MJGL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18374
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47228
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.56197
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78441
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1597
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2935
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864234
A-CA-04-2009(H1N1)_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.02266
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878486
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00549
COMBRETASTATIN A4	DGIdb Drug Targets 2026	1.0	1.12025
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Tight junction	KEGG Pathways 2026	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.04297
BRD-K70412800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10914
MAYTANSINE	DGIdb Drug Targets 2026	1.0	0.315071
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
MRAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00569202
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
Palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.399
dexpropranolol-5814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2556
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AZI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3671
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2366
prenylamine-5489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58137366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19493
pyrimethamine-4779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nimodipine-6320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
NCI-H23 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
BRD-A07870296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18519
Perturb_15489_KD_SMARCA4_SRP218853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.48046
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94671
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935867
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01383
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
BRD-K90205159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11555
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939989
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14817
aminophenazone-6818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dextromethorphan-1281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46484
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89372
BRD-K66912462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16094
BRD-K91419355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10631
MDA-MB-436 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396465
GGT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20646
hexamethonium bromide-4965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98931
BRD-K08009212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07075
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09877
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07187
Nucleomorph	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
mp12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36211
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864976
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08653
BRD-K62612761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62009
BRD-K92712671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37284
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02599
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47866
bromperidol-7457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039472
BRD-K64393896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00853
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04102
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
L1236	CCLE Cell Line Gene CNV Profiles	1.0	2.12736
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	2.11451
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
VWA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74649
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1752
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfafurazole-4661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
trichlormethiazide-4198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
MEKK6	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GAPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540869
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28837
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27607
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
BRD-K07540687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45549
Prestwick-674-2179	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.78759
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35298
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724453
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852215
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25694
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839188
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21239
sc71	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13014_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.8017
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-A95239561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25152
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75574
TBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35593
BRD-A88237615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21383
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15467
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79012
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19428
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02667
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08854
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843097
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11768
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91747
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
LY-294002-1641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32327
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08223
sulfadimidine-3422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Phragmoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50749
BRD-K29039402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45006
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
rosiglitazone-6950	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40196
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97794
PLA2G12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20742
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39584
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06778
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85564
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
BCB000040-7554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63959
HOP-62 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
USF1	ENCODE Transcription Factor Targets	1.0	null
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
BRD-K93472147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20942
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82734
metanephrine-6734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IgSF CAM signaling	KEGG Pathways 2026	1.0	null
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16757
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01369
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14668
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35214
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21967
hydroquinine-2767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.57392
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
BRD-K47504528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04501
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10243
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4573
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89183
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00504
Eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27645
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043097
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5562
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11471
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.119
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05042
GTEX-XOTO-2826-SM-4B65I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999465
VORINOSTAT	DGIdb Drug Targets 2026	1.0	0.10288
cycloserine-7134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838136
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19114
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27579
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.05155
AHSA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73438
retrorsine-4946	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bisoprolol-5348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.570833
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48822
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374994
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49315
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95518
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15117
dipyridamole-1934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35916
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
marc145	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
CCRF-CEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07025
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61035
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0525
EIF3M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48352
RD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60749
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Embryonic syncytium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09462
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13437
pimethixene-7426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.11868
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02178
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905404
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977873
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93716
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10976
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02919
UACC-2534 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
yohimbine-1763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
guanyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	1.0	2.03668
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.414
sulfadimethoxine-4724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16331
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936739
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989814
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.20097
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38419
BRD-K95788660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4491
Blastodisc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46494135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06416
benzthiazide-4952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7818
levocabastine-3509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hMPV_6Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.30875
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88424
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HC toxin-909	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
H3C8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00673836
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13223
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14261
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.292
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990399
BRD-K25187028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01495
BRD-K93737936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10063
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943083
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45817496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50261
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22231
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39675
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85756
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
Microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.505
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86576
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05611
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25803
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.73436
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XGQ4-1826-SM-4AT6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895036
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00563
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102772
GTEX-V955-1826-SM-4JBIL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882397
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
alpha-estradiol-6970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
letrozole_homo sapiens_gpl3921_gse33366	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
CHEMBL:CHEMBL453818	DGIdb Drug Targets 2026	1.0	0.315071
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
Cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.502
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25131
NEK6	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE130620_1_v_0_kdm4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79566
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09382
BRD-K59149254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24711
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90475
BRD-K94344234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16843
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
dizocilpine-2069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56638
palmatine-4957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6795
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04994
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874381
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27701
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
BRD-K14163107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
Pollen tube tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081765
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31632
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.351
mpp89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38819
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12807
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936021
meticrane-1792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69662
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4759-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nocodazole-7145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nimesulide-2112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046027
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43808
BRD-K91060460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16119
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hyoscyamine-5524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K98441254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19803
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01599
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61004
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.92499
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4963-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958594
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221061
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77889
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67507
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127732
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29384
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51684
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82454
mianserin-1385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30439
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
pilocarpine-3300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
piperine-4830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966704
BRD-K39396484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26056
BRD-K18296708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27823
ZNF599	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81054
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9179
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00423
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47315
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.25548
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21232
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
vinblastine-7551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K85776843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28795
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2306
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93961
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
mesoridazine-2874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57425
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976274
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.64491
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314772
BRD-K05339908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05005
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14371
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068658
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55819
molindone-4784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11236
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8623
NCI-H2087 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
pathogenic escherichia coli infection ehec	KEGG Pathways	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49425
BRD-K56214240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01844
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.926238
BCB000039-7531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6119
Lung adenocarcinoma_LUAD_TCGA-05-4418-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19094
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
pivmecillinam-2973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.74849
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.849142
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29355
TBC1D17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44925
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879052
propylthiouracil-4076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828966
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.16457
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32341
PMC5056720-pone.0164535.s001.xlsx-AR-DE_genes_with_KSC_p-val_05-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98495
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86007
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166884
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29241
BRD-K93127164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68056
BRD-K93032100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73816
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04693
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59954
BRD-K62085719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49296
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.843
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67497
Plant tumor tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Mitochondrial fatty acid beta-oxidation multienzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.38
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823973
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
BRD-K89923892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06423
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
BRD-K51666223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15197
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
BRD-K57202089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00527
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
BRD-K42392619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44017
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3934
12606954-table1a	GeneSigDB Published Gene Signatures	1.0	null
chr2_131479483_A_C_b38	GTEx eQTL 2025	1.0	5.81564
BRD-K07361992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03189
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
BRD-K21176869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14373
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29379
BRD-K82791632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70148
BRD-K67556876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00244
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325653
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908712
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35964
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
BRD-K28937085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8946
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
BRD-K35491869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10951
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244592
BRD-K81099637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67091
Plant cell papilla	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
nalidixic acid-4691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51298794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39545
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.006
BRD-K53326976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09452
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05149
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
BRD-K56131419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83616
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94015
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69542
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01839
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86877
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932395
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35158
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333137
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839008
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36629
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
ARID4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81512
496100313_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15344
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04811
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09992
Miracidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40604
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
nitrofurantoin-4697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08191
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50525
atropine-5865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.058
PF-00539745-00-5939	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	0.832976
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855616
CCD-841 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5899
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221291
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42029
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045601
Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10345
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18156
Plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TK10	BioGPS Cell Line Gene Expression Profiles	1.0	0.90149
BRD-K49530286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72693
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3517
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43878
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84399
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.343017
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92382
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38921
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15293
BRD-K86263698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3873
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
16424041-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00421
acetohexamide-1707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BC-15-EL49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274368
Tay-Sachs disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
ZNF705B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89438
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Podocyte primary projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09111
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3125
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24454
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84374
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10369
EBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75615
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47285
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8546
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05205967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19395
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848355
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74294
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84392
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63966
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EK-01A-22R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
BRD-K64535513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60839
tocainide-2931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12263
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66048
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
BRD-K51934291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68785
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57509
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920744
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.314969
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3069
quipazine-2782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0808
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9991
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39644
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900556
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72783
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94492
GTEX-TKQ1-1226-SM-4GICJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00668
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99134
hMPV_72Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59562
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
sulpiride-1467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1848
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15105
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05222
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21986
Macrogamete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
PAPSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0682
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050123
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00553
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44047
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
FBXL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21048
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.56156
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14741
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29032
prochlorperazine-1156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K24532680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38098
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27677
RRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63911
vidarabine-7203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
VINBLASTINE	DGIdb Drug Targets 2026	1.0	0.243926
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
metolazone-1932	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
BRD-K84278600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07272
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARGAZOLE	DGIdb Drug Targets 2026	1.0	0.173832
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.05711
pc-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.529508
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
fluspirilene-6662	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
PACLITAXEL PROTEIN-BOUND	DGIdb Drug Targets 2026	1.0	0.25852
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971757
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
Alzheimer disease	KEGG Pathways 2026	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931223
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61285
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18088
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.57392
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883271
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.328954
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890679
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51666
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61831
isopropamide iodide-7133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93971
BRD-K81623965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1247
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066736
KDM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563564
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68544
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL-60 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30312
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975668
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.40997
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00996
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908394
Lung adenocarcinoma_LUAD_TCGA-38-7271-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K17606413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86741
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832547
TNFRSF1A	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887163
BRD-K94582694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21693
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876678
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043752
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10276
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87796
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15489
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87175
BRD-K15907840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.94386
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00478
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
Trypanosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35914
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05901
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84926
BRD-K80593371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17168
CHEMBL:CHEMBL2036124	DGIdb Drug Targets 2026	1.0	0.315071
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869838
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-dORF6_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.55884
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886501
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16454
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
SHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15462
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93003
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32539
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97664
simvastatin-3340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MFSD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75952
haloperidol-4427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16491
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883405
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Tea1 cell-end complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54335
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989879
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57597
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340395
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2023	1.0	null
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
scopolamine-4803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Keratoconus	DisGeNET Gene-Disease Associations	1.0	null
14737219-CSRgenes	GeneSigDB Published Gene Signatures	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883405
OE-33 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.42462
5224221-839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
Prostate adenocarcinoma_PRAD_TCGA-G9-6353-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837975
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
Storage root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05036
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03
BRD-K67533212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89158
BRD-K07928699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12784
HT-1197 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
gliclazide-2870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31694
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16848
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29848
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02178
SETSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0208
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.933691
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.6099
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60225
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	0.936244
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02237
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47619
BRD-K46890865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41918
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07087
BRD-K22377875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03137
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	0.952142
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80843
phenethyl isothiocyanate	CTD Gene-Chemical Interactions	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31036
BRD-K54224946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77996
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.058
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
5279552-843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29144
BRD-K18515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85497
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
tridihexethyl-5486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40915
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08333
GTEX-S341-1126-SM-4AD6T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87472
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
BRD-K94489736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43478
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10068
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
ANAPC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78599
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
BRD-A05828965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05662
guanethidine-3171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Prion disease	KEGG Pathways 2026	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948554
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948554
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59639
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849014
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46536
asiaticoside-7004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89863047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41725
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56445
CWF19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06342
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05574
GTEX-S32W-1626-SM-4AD6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929101
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.318042
Dried cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.33914
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19004
Sporocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
IL17RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00494161
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
protriptyline-6338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93935
gabapentin-3472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
BRD-A35495382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04756
sulindac-1815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05134
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04312
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H292	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Teebi hypertelorism syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
BRD-K75440064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0897
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.601
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70696
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
LKB1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PF-00539745-00-5974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K35681049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27155
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991651
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91016
Microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43467
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.858953
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7985
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871143
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P-388 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31039
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF737	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84174
PMC10274745-media-4.xlsx-S3A-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69137
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11194
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08335
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
EB-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26601
PODOFILOX	DGIdb Drug Targets 2026	1.0	0.43836
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10142
harmalol-5495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51052
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88747
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863632
Zona pellucida	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45212
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842809
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06131
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96284
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34416
COLCHICINE	DGIdb Drug Targets 2026	1.0	0.395384
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98444
BRD-K40414902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14183
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.18869
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31755
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
BRD-K54236126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50531
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959754
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5905-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol-6968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1445
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34659
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
BRD-K33697018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10726
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941759
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70349
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
dexamethasone-123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
5637 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16692
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57919
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37005
antazoline-7128	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81222
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.20111
dihydrostreptomycin-2074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C3A	CCLE Cell Line Gene CNV Profiles	1.0	2.34171
a94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
BRD-K18178356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09423
calcium pantothenate-4775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1084
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989879
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
VINCRISTINE	DGIdb Drug Targets 2026	1.0	0.0998246
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13462
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8088
domperidone-5701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75687
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Supramolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.414
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44615
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02322
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K85284710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20621
Gin4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828966
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Taproot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86122
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01679
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921537
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8895
BRD-K11612998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22875
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10696
BRD-K22775880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20504
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02862
BRD-K28319429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31835
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.838
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.324512
BRD-K97748753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63551
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882537
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54599
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tretinoin-849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phensuximide-5097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20033
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.2927
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
BRD-K56161905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13016
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45564
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40769
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11194
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872686
GSE153443_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48753
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29109
triflusal-1717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HSC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
Fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77774
BRD-K99962919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10712
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10723
Pellicular membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
aceclofenac-2117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64341
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936739
CP-863187-7553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938671
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
BRD-K21284411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08067
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83166
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38077
nifedipine-6006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cyproheptadine-2021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12263
nifedipine-1814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882336
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.89532
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969057
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950784
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264608
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55504
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948197
betamethasone-6728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCABER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32621
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05006
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
BRD-K25822126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26548
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32139
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2592
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33287
BRD-K55867695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91766
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7349
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAYTANSINOL	DGIdb Drug Targets 2026	1.0	0.315071
dacarbazine-2754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23316
BRD-K22447639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48334
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40991
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901118
BRD-K89432538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32555
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12002
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52559
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43812
BRD-K43775480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75337
tretinoin-6931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.394
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
Cell plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24175
Alpha tubulin	InterPro Predicted Protein Domain Annotations	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04335
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7881
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
BAX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00341208
rolipram-5330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840783
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6C-Table_S6C_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_PRAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
parthenolide-2885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87037
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42665
uterus	GTEx Tissue Gene Expression Profiles	1.0	0.902354
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13617
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65888
kanamycin-5686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10114
BRD-K16739515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64588
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04394
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
Cellular bud neck septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42547
ornidazole-2272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Methylosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45771
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5489
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84374
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18198
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41186
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991874
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039618
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854323
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83820627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76234
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05083
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
Myosin X complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.67
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09512
gemfibrozil-5488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27531
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997318
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979297
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
BRD-K79885457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27131
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878471
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.037
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2485
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32728
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936739
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AG-013608-5944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68355
BRD-K16885048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21983
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04351
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039643
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
Leaf tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
BRD-K16268355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0907
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
BRD-K45092891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21898
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
VINORELBINE	DGIdb Drug Targets 2026	1.0	0.201646
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87103
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01272
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32808
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31765
BRD-K89399989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23823
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07346
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92803
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84699
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35637
CDK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508276
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
CCDC28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02859
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05873
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828438
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61345
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6715
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
14695196-Table2	GeneSigDB Published Gene Signatures	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9224
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13085
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.702111
BRD-K38424085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32862
5c9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Nucleoplasmic side of nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51105
BRD-K54250149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10961
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13275
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02213
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.57392
piperacetazine-7191	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.004
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eukaryotic translation elongation factor 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23993
BRD-K04238122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18162
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56398
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971683
oxaprozin-863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7487-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
GTEX-XUJ4-1926-SM-4BOOV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851414
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86016
BRD-K28320832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23139
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01803
ioxaglic acid-3528	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PTPN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07299
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17424
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13938
BRD-K15280583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49426
zomepirac-6815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-890	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982851
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982843
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857519
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68219
molindone-7337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ibrs2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
Small cell ovarian carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927673
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98689
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
flunisolide-3923	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204384
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863558
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12058
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260558
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7126
BRD-K22093396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17612
BRD-A02612852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02082
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17567
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20051
pentoxifylline-2127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cyanocobalamin-4395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1166
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932376
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26755
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23101
L-1210 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2853
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06417
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865685
chaperonin-containing T-complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
Pyrenoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
cinchonine-2789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73774
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02347
BRD-K31010207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46132
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39105
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54346
GTP binding	GO Molecular Function Annotations 2023	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.35294
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19928
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826432
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850994
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06355
BRD-K47536398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47981
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99563
mephenesin-4698	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06975
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99064
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06164
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17221
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51520673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56589
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95759
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908695
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43933
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
EW-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K52500055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60536
amitriptyline-1701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11471
LY-294002-4463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
alprenolol-7141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.012
imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06912
yohimbine-7130	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910006
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51274
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
valproic acid-1639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IKBKB	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898123
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
levothyroxine sodium-3249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.949054
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3704
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7276
diazoxide-5810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84707
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83722
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
BRD-K46703028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73754
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.626
SAF-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0329
BRD-K29218981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08835
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06413
levamisole-1410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nes	HPA Cell Line Gene Expression Profiles	-1.0	-0.934146
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1814
BRD-K50575036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02437
mepyramine-7223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
mevalolactone-3459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868189
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.972648
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6253
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894802
rimexolone-3516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Urothelial carcinoma_Urothelium_GSE3167	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.35477
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52261
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
Tubulin	InterPro Predicted Protein Domain Annotations	1.0	null
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46882
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36573
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00605
T-lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2715
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09553
gabapentin-7229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
benperidol-4196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
piromidic acid-3335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880177
biperiden-5279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066654
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08844
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.831585
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93985
PHF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60161
pronetalol-4104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
FOXRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00843
cromoglicic acid-3475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79673
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94446
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17294
CURCUMIN	DGIdb Drug Targets 2026	1.0	0.0933545
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Transitional cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39593
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56601
stachydrine-6805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF-7/LCC9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42152
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.467
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11194
chlorpromazine-1642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
BL70	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69888
POLR2A	ENCODE Transcription Factor Targets	1.0	null
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90493
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
Endoplasmic reticulum palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.417
BRD-K08927194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54863
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
Uroepithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
niflumic acid-2399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12340493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53927
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95738
GJD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94398
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
methoxamine-4972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRAF6	Hub Proteins Protein-Protein Interactions	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936739
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14245
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39441
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69858
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K27915221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35985
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3409
cefotetan-4116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64685
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998504
Tubulin/FtsZ, 2-layer sandwich domain	InterPro Predicted Protein Domain Annotations	1.0	null
Primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36686
pindolol-2075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45037
UM-UC-14 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
Pathogenic Escherichia coli infection	KEGG Pathways 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039866
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
MTHFD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69258
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.62257
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04196
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17260014-Table1	GeneSigDB Published Gene Signatures	1.0	null
anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17092
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
benperidol-2836	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4667
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81938
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911641
BRD-K15827385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27563
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75605
minaprine-1468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NUGC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
HCMV_24Hour-Infection_only_21084488_GSE24238	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35478
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supramolecular fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.414
Spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
F12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00507899
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18018
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7447
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049151
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
Hepa-1c1c7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
Phagosome	KEGG Pathways 2026	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47847
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58432332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70162
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.29
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77652
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846233
verapamil-6287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25912
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21984
Adenocarcinoma of lung_Lung Tissue_GSE1037	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.83923
BRD-K68605096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07807
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396465
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
BRD-K74694052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40273
Protozoan Infection_Intestinal Epithelium_GSE2077	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.8067
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
adenosine phosphate-5359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65571
12917485-Table9	GeneSigDB Published Gene Signatures	1.0	null
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26997
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24496
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
BRD-A50701104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77047
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898515
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
647V	CCLE Cell Line Gene CNV Profiles	-1.0	-3.12027
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3537
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978015
Trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831209
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858158
bretylium tosilate-5020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.562
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42676
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05989
BRD-K52978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25719
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958212
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.948554
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2382
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6002
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05765
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17851
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27201
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01857
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13215
DNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95115
ESCRT IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
meteneprost-7500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100454_FWM_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15527
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
CALO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91083
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1532
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92081
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44746
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13887
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875375
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18879
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03976
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9288037__F1	PFOCR Pathway Figure Associations 2024	1.0	null
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17921
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
MIR122_OE_GDS3470_573_human_Embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49721
RALGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29013
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92897
BRD-K13317726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23654
Parkin ubiquitin proteasomal system pathway	WikiPathways Pathways 2024	1.0	null
estradiol_homo sapiens_gpl96_gds2324	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K77706833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64216
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47123
methapyrilene-4990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.16249
Kenny-Caffey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
CHEMBL:CHEMBL1935538	DGIdb Drug Targets 2026	1.0	0.296538
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07921
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18652
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989879
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84902
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05156
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10172
blebbistatin-954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Phosphopyruvate hydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0167
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16722
BRD-K96254487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09708
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52130884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13765
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.877737
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
Plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47478
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
PMC6405523-fgene-10-00023.nxml--FOXJ1_Target_Gene_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05972
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00903
BRD-K71339292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09412
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BAX complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97065
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
EPB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53089
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00106
NDUFV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00446479
BRD-K48727830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9574
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07033
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00192
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25655
PMC6766969-PATH-249-90-s006.xlsx-TAB_S2_b-Supplementary_Table_S2_b_Top_100_upregulated_and_downregulated_genes_in_TAF15-NR4A3_vs_EWSR1-NR4A3_engineered_cell_models_NR4A3	Rummagene Transcription Factor Associations 2026	1.0	null
REF-52 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2316
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64977
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843329
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925181
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
BB-11-JI42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298546
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.664
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54564
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77816
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
SARS-CoV_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7186
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06139
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
Rix1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38592
SYNCRIP_KD_GDS3578_86_human_MM1S	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37943
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
ADCK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00513311
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
BRD-K36031198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60295
ARC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36185
Tubulin/FtsZ, GTPase domain	InterPro Predicted Protein Domain Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89795
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11013450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98788
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07506
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31859
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04427
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891406
Ulcerative Colitis_Peripheral blood mononuclear cell_GSE3365	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.58208
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72663
Pathogenic Escherichia coli infection(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PURG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96995
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45324
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
Secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
FO-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15434
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979504
BRD-K11873306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44058
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0827
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052219
Hemicellulose network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84009
protein-cysteine S-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5317
colforsin-7055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980364
BRD-K52148119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7223
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4465
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16213
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323226
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888766
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873216
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
oxprenolol-7225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LY-294002-5937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A55020151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09964
P05888	Virus MINT Protein-Viral Protein Interactions	1.0	null
Photosystem II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48278
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51393
BRD-K19036695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41544
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25288
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87957
BRD-K36340167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05251
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cho/dhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.953859
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
istmes1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
USF2	ENCODE Transcription Factor Targets	1.0	null
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03141
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14392
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32594
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.49864
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12493
BRD-A79884839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36368
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03913
NOCODAZOLE	DGIdb Drug Targets 2026	1.0	0.630143
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06764
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.86435
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79548
TPBG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59531
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.20557
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79555
SU8686	CCLE Cell Line Gene CNV Profiles	1.0	1.34191
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6747
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
Huntington disease	KEGG Pathways 2026	1.0	null
BRD-K55857083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50108
BRD-K72700187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28895
BRD-K64602559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96665
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895505
Supramolecular polymer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.414
Static microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.909
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6169
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87646
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847547
Oblique facial clefting 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900584
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K20951097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21339
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
Poisoning	CTD Gene-Disease Associations	1.0	1.22016
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.979
ZAMPANOLIDE	DGIdb Drug Targets 2026	1.0	0.315071
KB-3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
Synganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2621
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.267
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49799
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52059
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28264
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2853
TRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76422
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
GW-8510-7062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
APOC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604555
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.284
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33275
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SRGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65322
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82097
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
amikacin-5314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3776
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18696
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K21467089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16097
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2502
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243602
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36783
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29892
germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572418
peg16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51434
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95648
oxybutynin-7126	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3511
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5655
prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260891
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.02445
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052015
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60479
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05052
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858284
cilium	GO Cellular Component Annotations 2025	1.0	null
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37482
TRAF2	Hub Proteins Protein-Protein Interactions	1.0	null
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.446
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26851
sulfadimidine-3847	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926887
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69601
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
droperidol-1290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62533881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29838
CYCLOSTREPTIN	DGIdb Drug Targets 2026	1.0	0.315071
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864071
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2979
sirolimus-4431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29203
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26097
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54338
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88194
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7404
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0709
GSE89154_1_v_2_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cleavage apparatus septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00045
cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2708
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.02978
BRD-K77046858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16325
Epicuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
minaprine-4814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057253
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06627
vinblastine-7556	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.25
clidinium bromide-6837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pathogenic Escherichia coli infection	WikiPathways Pathways 2024	1.0	null
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38803
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
CYBC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95826
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956496
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046068
heart	GTEx Tissue Gene Expression Profiles	1.0	2.13624
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04742
qt6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45207
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233446
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10125
BRD-K04147413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17155
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50086
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48327
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37796
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875735
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
carbarsone-3250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08425
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.989879
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
RECQL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0363
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843764
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40559
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04971
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95019
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20012
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95111
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.47111
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35801
INIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15498
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49627
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42429
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27085
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64413
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12263
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
esculin-3052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
tolbutamide-3804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-1376	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K35347834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07774
BRD-K70305913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01828
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45322
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
parthenolide-5530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
Seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.858
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
rosiglitazone-1013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04876
BRD-K36074653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53164
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09523
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
Perturb_2604_OE_SEPTIN9_SRP159553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.4347
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.67181
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11033
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12445
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29748
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00611
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92586
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24425
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50759
CCDC71L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76036
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837567
hek293	HPA Cell Line Gene Expression Profiles	1.0	0.894748
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10321
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94116
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40958
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9161
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883679
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.066
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79647
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908201
istmes2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98406
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K40513181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78184
BRD-K51787437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.072
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8633
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88087
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84374
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7144
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853957
TNNI3K	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476184
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41886
zoxazolamine-1270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
Hak	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
ACSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75336
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
14695196-Table4	GeneSigDB Published Gene Signatures	1.0	null
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99393
BRD-K78904317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26642
GTP binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48509
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37152
Cloneh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38057
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11194
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40489
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960029
pioglitazone-7088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67597
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08268
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84374
etodolac-7006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05261060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53428
Bloodstream form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
pipenzolate bromide-3460	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97128200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44393
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02581
BRD-A45498368_WYE-125132_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15277
15520196-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
ZNF772	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67023
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.25729
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60254
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07006
MAX	ENCODE Transcription Factor Targets	1.0	null
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.27458
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16783
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
BRD-A25243629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04103
Plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
11-deoxy-16,16-dimethylprostaglandin E2-7533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08432
BRD-A23434937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1211
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963277
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03909
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21334
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058759
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3733
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941732
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00293
u266	HPA Cell Line Gene Expression Profiles	1.0	1.20654
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00329
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942259
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939695
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66983
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2354
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
microtubule	GO Cellular Component Annotations 2025	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12038
BRD-A50737080_CGK-733_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40X-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88947
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01308
LRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41948
HEK-293ET cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
BRD-K45717258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64003
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23131
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
Hemolymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Salmonella infection	KEGG Pathways 2026	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960978
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3522
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914304
19861896-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
cc81	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61179
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35745
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18985
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90804
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81664
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57105
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
Tubulin, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60902
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23431
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4506
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
BRD-K58113140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88719
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62617
Perturb_407_OE_DPP4_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42415
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061947
viomycin-2979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clofilium tosylate-6830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Male inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
SMOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058313
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chlorpromazine-6936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07244
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09879
PERK	Kinase Library Serine Threonine Kinome Atlas	1.0	null
BRD-K32577562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53516
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39605
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2995
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24724
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
BRD-K76921877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5945
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25097
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70572
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34817
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
pyrvinium-3518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56103
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62459
thioproperazine-2073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.022
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
PANC0504	CCLE Cell Line Gene CNV Profiles	1.0	1.50964
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTUD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31004
BRD-K15098674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08467
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2025
beta-galactosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.097
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10467
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
BRD-A14331394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59022
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16168
BRD-K04367224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42021
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31797
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
RAB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84957
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07744
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89648
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65194
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13049
BRD-K25525067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25829
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
DNAJC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94756
INA-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49391
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998324
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	1.421
Tick infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08879
cefapirin-7142	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null