association	dataset	threshold value	standardized value
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36854
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.32015
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947462
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19046
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225009
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8895
NS-398-6897	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08234
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72301
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.639226
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825145
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94918
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78272
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49362
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04643
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4521
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16476
BRD-K94090114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17684
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28942
Atypical autism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Fulvestrant_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00738303
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.031577
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52075209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75465
localization	GeneRIF Biological Term Annotations	1.0	null
RAB3A_KO_GDS2483_701_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98162
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0538
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.804
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.72395
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194717
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24495
GATA3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0828
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1571
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.09122
BRD-K14309706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62653
A549_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0235481
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.299
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23946
BRD-K49707067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51294
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09306
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16838
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92168
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
BT474	CCLE Cell Line Gene Expression Profiles	1.0	2.04048
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866523
CALU3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47043
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909519
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38855
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43309
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18558
TUBG2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866258
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.34195
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35326
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06542
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.991535
STAT4	ChEA Transcription Factor Targets	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74232
BRD-K30782795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5805
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07309
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845886
TUBGCP2	NURSA Protein-Protein Interactions	1.0	0.571353
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.93166
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.29005
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.72431
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.97633
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-ARGFX_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831481
PMC12368524-Supplementary_materials.pdf-33-DZIP1_DZIP1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34093
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32439647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15326
medrysone-2544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09308
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.901
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18818
COMMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03588
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89266
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1633
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT15_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.13016
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SG-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polyhydramnios	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
lomustine-7050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6758
tilorone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44686
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96708215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47865
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.076122
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15853
COLO-205	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56468
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7913
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2703
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257304
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.00413
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22545
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06677
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32178
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
coralyne-1298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clozapine-1170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1338
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01327
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45783
BICR56	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47304
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28624
hsa-miR-595	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47365
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32503
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19313
BRD-K50053371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16646
Angelman Syndrome	DisGeNET Gene-Disease Associations	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Burkitt lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24852
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Resveratrol_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167252
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dyslexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.307
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-00-IL62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248755
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23452
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76428
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.996783
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2076_DCTN4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.596707
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.48541
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46335
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02557
DOHH2	CCLE Cell Line Gene Expression Profiles	1.0	1.59991
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851631
disease	GWASdb SNP-Disease Associations	1.0	0.026699
Triglyceride levels x loop diuretics use interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0645
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3929
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04941
Prader-Willi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72001
A549_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138859
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8864
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62811
sitosterol-7332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154076
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7674
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27452
aminophenazone-6818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36445086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5041
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48957
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933706
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3439
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HA-27-FV67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23029
CRCGN010_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30033
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44829
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01525
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02206
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_CYC116_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110023
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K55218521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01224
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09408
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38691
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
pridinol-7214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848848
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21476
GSE149075_8_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16383
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00405
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224986
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885809
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.94561
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33935
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21861
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule minus-end binding	GO Molecular Function Annotations 2025	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K31874013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31507
A549_Lomustine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162325
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43309
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47633
Spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.911
Chromosome 17q12 duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02721
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3406
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
A549_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115718
chr15_23056355_T_G_b38	GTEx eQTL 2025	1.0	1.34527
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.12301
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171527
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05972
Methionine	CTD Gene-Chemical Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.96311
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29152
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.05959
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923027
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52635
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3316
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40405
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3951
PMC3443648-1752-0509-6-89-S1.xls-Sheet1-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86491317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43803
A549_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163662
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.897
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14259
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_7239_KO_CDK8_SRP271652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
A549_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0336629
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985139
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24068
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67371
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0601
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02248
Pitt-Hopkins syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBGCP3	NURSA Protein-Protein Interactions	1.0	0.571353
vidarabine-5850	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29298614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71695
MAFK	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-509-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
CRCGN016_MCF10A.TP53.M_24H:D21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01823
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0723
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1962
hsa-miR-4437	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Asperger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
proton-transporting two-sector ATPase complex, catalytic domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49753
BE-74-SX40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257343
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16074
BRD-K53198140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27951
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
butacaine-6225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943828
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849302
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.39566
hsa-miR-450b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225643
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60726
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316751
KYSE30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11223
BL5638 (AKAP13)	NURSA Protein Complexes	1.0	null
UBLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57246
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44666
A549_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144861
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98377
A549_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202267
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.237
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.981587
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TK10	GDSC Cell Line Gene Expression Profiles	1.0	1.47455
BRD-A27080191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38345
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834177
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975613
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_ABT-737_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0356877
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terbutaline-3202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165164
BRD-K17549032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19434
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36732
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33003
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446807
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54053991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01313
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
disopyramide-7439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198634
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2412
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PCI-34051_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147849
BRD-K66207462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40134
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10596
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.76915
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00941
proper	GeneRIF Biological Term Annotations	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58176
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948313
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159148
BRD-K01705159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9987
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04599
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.152
Lung adenocarcinoma_LUAD_TCGA-75-7031-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72998
MCF7_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138158
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01732
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A549_Navitoclax_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146939
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31553
MCF7_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163514
gossypol-2202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0577
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6545
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919406
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PSIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01143
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1879
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38736
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270309
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49902
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70636
Adrenocortical carcinoma_ACC_TCGA-OR-A5LB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32895
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945446
CTV-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44435
CDK7_knockdown_124_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74822
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964459
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7557-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15137
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59741
TCF7L2_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.35
clomipramine-6825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.266
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67216
Oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
syndromes	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-378e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K37328981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77736
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20685
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57935
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42203
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96051
KASUMI2	CCLE Cell Line Gene Expression Profiles	1.0	1.59171
milrinone-5856	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00636
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2764
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31611
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09884
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74936
BRD-K50721666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61626
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16899
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5096
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BRD-K85055578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28488
MCAS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80499
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04965
VLX-600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05758
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82774801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37378
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09528
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Reading disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.314
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49644
thereby	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07506
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27688
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981118
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11539
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228764
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51107
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65401
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873167
A549_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015434
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.546266
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19105
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69658
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34352
15q11 2 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81213
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2414
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899322
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.599
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
Phragmoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
microtubule-based process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.09016
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140981
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52896
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954165
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K48813201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45339
Cell Cycle	Reactome Pathways 2014	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38462
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895397
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15726
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3295
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31466024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25422
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27398
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06588
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.2557
BRD-K67409155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73365
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.884
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.524838
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	2.06411
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52313
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71521
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.7025
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841485
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.85667
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01167
Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35748
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01336
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosome 15q13.3 microdeletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852423
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5135
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3120-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CC-21-IE22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351561
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3822
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86767
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4039
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC2152 (RFWD3)	NURSA Protein Complexes	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85169
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80161
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.77697
BRD-K42849858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.425
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04736
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15763
chromosome	GeneRIF Biological Term Annotations	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01667
Polar microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30271
MCF7_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196479
A549_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212826
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63657
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10737
BRD-K55779851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07367
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04447
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075889
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02163
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25017
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849915
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68948
BRD-A80968824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01077
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00293
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6160-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852157
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02583
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35137
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.01345
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49245
Prestwick-665-6041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.60154
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904816
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13682
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19565
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11572
BRD-K59294904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09175
Prostate adenocarcinoma_PRAD_TCGA-EJ-5512-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.518805
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100986
CRCGN015_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14007
hsa-miR-130b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34464
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957999
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0068
BRD-K79067166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41402
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	1.39446
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927408
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51449
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
naringin-5666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PEER	CCLE Cell Line Gene Expression Profiles	1.0	1.9562
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34577
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13274
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43951
NET1_KD_GDS4196_437_human_AGS - gastric adenocarcinoma cells - (65 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98194
BL6680 (SETD7)	NURSA Protein Complexes	1.0	null
A549_ZM 447439_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194271
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91154
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826384
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26393435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83196
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18587
BRD-K05610303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07588
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26967
Obsessive-compulsive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905272
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12479
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326374
BRD-K73775927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11147
Oppositional defiant disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-509-3-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84993
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6885354__F4	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21648
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17207
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52058
mitotic cell cycle process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-378h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
5163_MPHOSPH10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.507658
NCIH2110	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64887
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39551
methyldopate-7360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.628659
BRD-K18043221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61978
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587397
BRD-K42506600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06939
MAPK14_knockdown_101_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.26131
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08927
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.972
BRD-K27256143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38575
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27054
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07285
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154429
A549_PCI-34051_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0106374
K562_Raltitrexed_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162593
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910593
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2674
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5807
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
neomycin-7221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cavum septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38797
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912318
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34802
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18757
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle organization	GO Biological Process Annotations 2015	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A69P-06A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84665
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
59M	CCLE Cell Line Gene Expression Profiles	-1.0	-2.82135
GSE178714_3_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4296	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
2545_EIF3B_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50914
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36441
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20619
BRD-K32040515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60679
Hereditary spastic paraplegia 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.194799
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13153
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38255
tubulin binding	GO Molecular Function Annotations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20906316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0844
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.9714
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134916
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Preprophase band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.155214
BRD-K46839342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30973
cilium	GO Cellular Component Annotations 2025	1.0	null
NCIH1915	CCLE Cell Line Gene Expression Profiles	1.0	1.5091
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tozasertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174304
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0721
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14865132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52382
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5893
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_1_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02146
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_UNC1999_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112061
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.25831
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67979
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
COLO818	CCLE Cell Line Gene CNV Profiles	1.0	1.34964
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4Z9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytisine-2759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-1231	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30539
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494367
SARS-BatSRBD_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65313
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24532680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32578
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146955
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12598
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
benfluorex-1266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27734
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9051
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03563
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99458
Lung adenocarcinoma_LUAD_TCGA-99-8033-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3333
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24566
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81001899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3245
cytosol	GO Cellular Component Annotations 2015	1.0	null
ZBTB16-27035670-HESC-HUMAN-ENDOMETRIAL	ChEA Transcription Factor Targets 2022	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.339
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_0_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K73500713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53393
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142588_2_v_3_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
BRD-K67783817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12576
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8009
A549_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203151
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19892
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cefuroxime-6261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K35049668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33918
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5096
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877318
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35423
K562_WP1066_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150743
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050999
Brain Lower Grade Glioma_LGG_TCGA-FG-7641-01B-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
strophanthidin-7182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23478
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33446
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07818
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-1.06574
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18507
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96458
Cellulose microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.087
PADI4	ChEA Transcription Factor Targets	1.0	null
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
A549_Belinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214397
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitotic spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52385
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09103
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3152-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
huh-7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05189
doxorubicin_homo sapiens_gpl550_gse1647	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40812
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7753-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962965
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.371
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08436
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL8579 (MAP3K7IP1)	NURSA Protein Complexes	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33567
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986095
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01688
K562_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146621
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987236
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918582
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38882
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8195-01A-31R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10542
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22437
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28536
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451467
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:H14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6149
Childhood absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.286
A549_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142805
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05339
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K53757555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04869
Schaaf-Yang syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14429
mitotic cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87307
BRD-K63859730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7404
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26591929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26346
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.517649
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28261
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904871
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36938
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.09446
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14106
BHLHE40_02_186	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60569
BRD-K52094743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90783
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7395
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
milrinone-7210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22390389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0523
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99941
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857317
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917039
diethylstilbestrol-3429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.17754
GSE148200_1_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828337
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
proscillaridin-2920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1003
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973623
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01688
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36952018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41003
SYNCRIP_OE_GDS1806_82_human_T-lymphocytes from normal donors were activated with anti-CD3 and IL2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05871
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04573
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenoma_Colon_GSE4183	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51812
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3455
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11323
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8805
SRF	ENCODE Transcription Factor Targets	1.0	null
BRD-K66623602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33294
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2022
MUTZ5	CCLE Cell Line Gene CNV Profiles	1.0	1.57606
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-144	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bufexamac-5090	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0319
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23203
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
A549_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171341
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Nintedanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0288894
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Iniparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198603
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73742
BL4554 (ATXN10)	NURSA Protein Complexes	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45252
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99214
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spindle pole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ETS1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03187
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34437
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41495
KDM5B	ChEA Transcription Factor Targets	1.0	null
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
break	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.067
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6628
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76496
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05625
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21476
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE450_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.43208
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0307
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995297
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63464
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2156
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
streptomycin-7194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9303
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07703
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26226
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68882
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893053
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02884
CRCGN015_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.49078
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83779
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.140917
BRD-K48994888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54899
KAT2A	ENCODE Transcription Factor Targets	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265475
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9207
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988058
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235017_1_v_0_uba52_human	RummaGEO Gene Perturbation Signatures	1.0	null
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04264
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20V-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
10400_ZNF497_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.09539
hsa-miR-1284	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Luminespib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119685
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63901
A549_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187141
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55721
cinoxacin-6257	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.257
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03308716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66556
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889667
A549_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195178
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.44411
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.74072
A549_Iniparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138874
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.807
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K72773309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6995
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11341
thioridazine-4085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBG1	Pathway Commons Protein-Protein Interactions	1.0	null
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71412
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27169
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998732
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14696
A549_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159137
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3532
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07775
BRD-K58688519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84063
A549_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0101058
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3515
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140754
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.38507
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99387963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66951
TUBGCP3	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867736
Proprotein convertase 1/3 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12891
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45827
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200320_3_v_2_mfge8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.943936
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6636
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180067
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856386
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891863
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54434
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
correlated	GeneRIF Biological Term Annotations	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48126
eucatropine-3416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18089
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	0.8406
AKT1_OE_GDS2308_508_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A549_Hesperadin_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272497
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48102350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79344
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02164
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40841
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956696
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1695
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5795
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146823
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21476
CDK8_knockdown_88_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.25459
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.27113
BRD-K18128277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75018
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Roxadustat_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153747
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60695
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907893
DOHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cardiomyocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF	ChEA Transcription Factor Targets	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
RUNX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K63111122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10872
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1638
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-A43076080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2864
G2/M Transition	Reactome Pathways 2024	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1526
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
IRF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40719
TAF7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18306
Idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
PF-382	GDSC Cell Line Gene Expression Profiles	1.0	1.99762
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979389
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6183
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09528868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41601
Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13966
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293039
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22107
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943285
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
luteolin-5004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10311_KO_Dkk3_SRP067265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.19074
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.611626
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4885
GSE173405_3_v_0_dmba_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88876691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57927
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
BL586 (FEN1)	NURSA Protein Complexes	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38747
MCF7_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168873
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83175
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41853443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04953
cell cycle process	GO Biological Process Annotations 2015	1.0	null
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K80888628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01626
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0322489
mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.814
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A07870296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7904
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.21029
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0839
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6097
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5698-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
A549_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191208
RO82-W-1	GDSC Cell Line Gene Expression Profiles	1.0	1.79061
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital heart defects, hamartomas of tongue, and polysyndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
iopromide-3481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54646
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-1926-SM-3GIL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892354
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-378b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
A549_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122388
A549_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147595
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19353
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11792
A549_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0245249
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67526257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47223
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44309
A549_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152002
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25963
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8576
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Velocardiofacial syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3529	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3228
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04738
PMC8791942-41398_2021_1766_MOESM10_ESM.xlsx-UniqueTD_NT_LPS_NT_LTA-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01747
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23708
Acute Myeloid Leukemia_LAML_TCGA-AB-2845-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
trifluoperazine-1224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CALU3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15403
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50765
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5229
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289977
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39328
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62425
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98965
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NSUN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEDD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0193
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.768
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U4-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A4C1-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Altretamine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166107
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2346
A549_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193206
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20590138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00436
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48864953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42681
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91117
TBX5	ChEA Transcription Factor Targets	1.0	null
A549_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0287875
A549_IOX2_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210479
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12632
HUNK_knockout_240_GSE14226	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.5039
A549_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149618
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18349
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42838
BRD-K63487554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6372
nipa2l	GeneRIF Biological Term Annotations	1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911423
K562_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213126
A549_Ellagic acid_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136152
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07664
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05039
BRD-A15086915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37357
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0319
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-454	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30799912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32622
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNCRIP_KD_GDS3578_86_human_MM1S	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS620	CCLE Cell Line Gene Expression Profiles	1.0	2.35022
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11223
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
u698	HPA Cell Line Gene Expression Profiles	1.0	1.70493
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4426-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858597
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944864
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188774
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17616
2653_ENTPD7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.553851
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08102
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56705
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911865
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76814
gamma-tubulin small complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.416
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.903222
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
Anorexia nervosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
ELK1	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172146
thalidomide-2095	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497383
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4772
valproic acid-6934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03626
PSMD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86557
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.880305
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39173
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.201
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.50702
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84019
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36676
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937045
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40133
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62844
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9582
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SU-DHL-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352039
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61102
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38321
meropenem-7180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88165
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910609
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17134
hsa-miR-330-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Neurofilament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.353
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48219
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6269
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21579
A549_2-Methoxyestradiol_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226824
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.386
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16967
MCF7_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112203
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
KE-37 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73685
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ifenprodil-7404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06158
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8568
BRD-K72892670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23528
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12144
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10822
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.879
pseudopelletierine-7184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0238226
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26843
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12365
A549_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175583
MYC	ChEA Transcription Factor Targets	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5448
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.813
semustine-7492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12133
K562_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187725
BRD-K26682747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.279
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94833
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859686
E2A_KO_GDS5084_401_mouse_DN2 thymocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7054
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.236
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62469
Corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143714
A549_SRT1720 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140283
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61586
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849429
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.21288
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97864
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9104
A549_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033776
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eucatropine-2556	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR4	BioGPS Cell Line Gene Expression Profiles	1.0	1.49216
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12432
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54646
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29194
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBG1	NURSA Protein-Protein Interactions	1.0	0.508804
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
A549_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144593
A549_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154746
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00138
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11148
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22694513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55718
Recruitment of mitotic centrosome proteins and complexes	Reactome Pathways 2024	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67923
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZT2B	Pathway Commons Protein-Protein Interactions	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49089
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.91312
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00427
hsa-miR-618	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-548m	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08747
A549_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131482
RKN	CCLE Cell Line Gene CNV Profiles	1.0	1.668
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97464
Polar nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80306
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30057
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878809
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54916
isoconazole-7211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW403_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.13902
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18952
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
CAL-12T	GDSC Cell Line Gene Expression Profiles	-1.0	-2.71183
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43883
trichostatin A-7245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07438289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03913
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17268
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.37719
TAF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01781
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63625
BL4168 (DTL)	NURSA Protein Complexes	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5037
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6828
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dacarbazine-6816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34454
4951_MED28_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.50804
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.584
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acronycine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2829
Intraparietal sulcus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.834378
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2769
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826274
PFEIFFER	CCLE Cell Line Gene Expression Profiles	1.0	1.36647
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12785
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97107
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04357
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07588
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850013
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53276
BRD-A10134527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84703
A549_Barasertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154116
FOXO1_KD_GDS2720_477_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09072
GSE154069_2_v_4_satb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06294
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853804
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854261
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19214
BRD-K42877297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07643
BB-93-VT73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210705
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36779
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201153
A549_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170536
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418345
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88366
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25226
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMC18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66396
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6487
thioridazine-5921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DU-145	GDSC Cell Line Gene Expression Profiles	1.0	2.33515
ZNF274-21170338-K562-HELA	ChEA Transcription Factor Targets 2022	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00416
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887846
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56679
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07673
Developmental Delay (Disorder)	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13818
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05134
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91423144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2366
benzathine benzylpenicillin-7359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21636
Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42293
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69488
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918576
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981082
Cohen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
BACH1	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
magnocellular diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83759
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33402
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29745
BRD-K15485967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11485
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31071
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.04475
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12679
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
BRD-K72835476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9541
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879498
Prostate adenocarcinoma_PRAD_TCGA-HC-8256-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1355_LUNG	CCLE Cell Line Proteomics	1.0	2.98335
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07313
MCF7_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143189
moracizine-7297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14281
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
PMC9949195-media-2.xlsx-25_WHI_AA-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49328
A549_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0236058
microtubule	GO Cellular Component Annotations 2015	1.0	null
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
spindle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.924483
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14752
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973701
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13614
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26763
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15667
Fetal Death	CTD Gene-Disease Associations	1.0	1.07128
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3057
BRD-K85168571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53826
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.43919
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04693
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.765384
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9001
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91682
BRD-K63271817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38704
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66735533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36813
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.428112
BRD-K76899562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16228
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.38725
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23197
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8329
A549_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015003
Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
A549_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115936
FOS	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.860593
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UT7	CCLE Cell Line Gene Expression Profiles	1.0	1.55796
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20833
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BL666 (BIRC6)	NURSA Protein Complexes	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03563
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32755
A549_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0255286
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.955696
ISTMES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72444
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96787
BRD-K46306993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38698
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7299
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.78643
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.947533
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44407
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
meteneprost-7552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EMC-BAC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3272
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.036
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31916
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spindle	GeneRIF Biological Term Annotations	1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.35837
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4072
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0001
intracellular non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
A549_Baricitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197671
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826088
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31916
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56037
PFKFB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635121
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.52773
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21948
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosome 15q11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.805
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13336710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07547
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35754
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56124
TUBGCP6	Pathway Commons Protein-Protein Interactions	1.0	null
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316146
MTA3	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18689
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881858
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32158
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02834
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1569
hsa-miR-301b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00045
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.086
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928944
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-TD_NT_LPS_or_NT_LTA-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.93204
dinoprostone-6586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123037
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81869
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.837656
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17915
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135764
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72126
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130371
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.592116
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTBP1_02_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62191
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51039
A549_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167807
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Thalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149991
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K22698363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95226
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16233
A549_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163234
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16262
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.205
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06724
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.45698
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63821
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.897681
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855065
A-CA-04-2009(H1N1)_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.1851
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16667
BRD-K94273044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37121
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93182
A549_FLLL32_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143567
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41599
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMOD3	Pathway Commons Protein-Protein Interactions	1.0	null
Echolalia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6599
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2241
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Nuclear microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-TD_NT_LPS_or_NT_LTA-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830743
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960411
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27651
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Quisinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119073
NCIH524	CCLE Cell Line Gene Expression Profiles	1.0	2.44883
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54452
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49789
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8885
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4583-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89798
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20215
K562_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167466
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24359
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3315
GSE193249_0_v_1_gpx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
benzylpenicillin-6155	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K00020149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09352
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.71606
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302904
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33122
cellular component organization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08755
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28134
NCI-H747	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47576
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830137
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7106
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198295
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885524
RF-48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893177
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08083
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
BRD-K32916996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.914
CRCGN017_MCF10A.WT.HP_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0569
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26047
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65345
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882024
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19692
Mitotic G2-G2/M phases	Reactome Pathways 2014	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907973
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940407
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05882
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BL5657 (ANKZF1)	NURSA Protein Complexes	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1703
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14955
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976466
Lateral meningocele syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58253
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80737
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932539
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78447
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27188
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53836
BRD-K42529194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24289
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16967
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47358
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0219
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.14477
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06685
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558952
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60776
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_17_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TUBG2	NURSA Protein-Protein Interactions	1.0	0.544509
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEC1	CCLE Cell Line Gene Expression Profiles	1.0	1.48233
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.04389
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34112
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2126_LUNG	CCLE Cell Line Proteomics	1.0	2.27986
BRD-K57059449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35727
MHHCALL3	CCLE Cell Line Gene Expression Profiles	1.0	1.50556
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60850201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32046
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01837
microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AT9283_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130978
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07986
Mowat-Wilson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.035
SF295_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	5.50675
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869193
MONO-MAC-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06625
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.37443
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45917
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.739894
KDM4A	ENCODE Transcription Factor Targets	1.0	null
gcp5	GeneRIF Biological Term Annotations	1.0	null
Paragigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01021
Antipodal site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35169
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88396
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63863
prenylamine-5070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LIVF001-021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19648
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48515
NUGC2	CCLE Cell Line Gene Expression Profiles	-1.0	-3.46167
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16967
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7188
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
SMN-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26343
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54874
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71775
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94966
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04794
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838973
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC56_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	6.60948
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55799
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08431
Spindle midzone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
CRCGN017_MCF10A.TP53.M_24H:J02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11515
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.89224
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942626
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi cis cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87851
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98915
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09435
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54818
Equatorial microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.232
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCIH2286_LUNG	CCLE Cell Line Proteomics	1.0	2.02019
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31243
line14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
A549_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186834
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02389
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.487507
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3586
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2043
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56226
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988842
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.928
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44809
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163878
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08943
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02652
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61318
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
TUBGCP2	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
K562_Veliparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239488
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934565
A549_Panobinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143516
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924208
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.79777
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03921
CAL-39	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41705
microcephaly-micromelia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01367
SAP30	ENCODE Transcription Factor Targets	1.0	null
A549_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015413
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10293
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86793
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18383
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24492
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24566
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00928388
MCF7_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153302
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09423
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52325
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4318
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851623
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ring	GeneRIF Biological Term Annotations	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
spindle pole	GO Cellular Component Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18982
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4544
Temple syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10998
BRD-K81006490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13978
BRD-K12239796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76596
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC70	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14788
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13204
GSE81803,GSE81912_4_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	2.28203
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2423
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328329
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33866
binding	GO Molecular Function Annotations 2015	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350836
diazoxide-7168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1996
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46406
8272_SON_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.581501
BL6517 (BMI1)	NURSA Protein Complexes	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20464
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_ITSA-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129898
BRD-K74918080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14174
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78038
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56588
ZEB1	ENCODE Transcription Factor Targets	1.0	null
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43985
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34603
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Toremifene Citrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146248
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
harmine-2750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
protein complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40945
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51624
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50233
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04697
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
GM2313	BioGPS Cell Line Gene Expression Profiles	1.0	1.61661
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
MCF7_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187254
NFIC	ENCODE Transcription Factor Targets	1.0	null
tracazolate-7339	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50562
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02145
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838635
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828752
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85922
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6606
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.848867
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16522
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136658
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377245
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8274
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule organizing center	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34513
vidarabine-3445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Parallel fiber to Purkinje cell synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02397
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10422
A172	GDSC Cell Line Gene Expression Profiles	-1.0	-2.02922
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00162
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218788
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kinetochore microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3228
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133354
Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0U-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6343
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6276_KD_GAS1_SRP050422	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00627
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D9-01B-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241266
A549_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169812
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6222
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central precocious puberty 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14451
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212569
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89493
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0278837
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
benzethonium chloride-7207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
BRD-K29820234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46478
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
BRD-K05432466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03664
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.998166
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974008
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238271
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58483
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.986656
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18432
ZNF274-21170338-K562_HELA_HEPG2_GM12878-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Old mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.78217
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-46-GL76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233486
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05995
BRD-K66311249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50824
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875272
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73699
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953222
A549_Pracinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017576
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.942019
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59498
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.617
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19564
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2658
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2729
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27208
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32549
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K35963610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28177
BRD-K86773205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2464
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32778
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44407
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.353
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69634
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0645
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70713
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.902
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03387
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4186
hsa-miR-3666	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Perturb_1657_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.20227
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25416
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.897098
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55935
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11856
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41641829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54034
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
MCF7_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139784
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55893
Recruitment of NuMA to mitotic centrosomes	Reactome Pathways 2014	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149723
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27554
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52446
tacrine-2633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20342
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145563
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03851
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19267
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33123
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24418561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09833
sanguinarine-2927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-21-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29283
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908062
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2908
CHD2	ENCODE Transcription Factor Targets	1.0	null
A549_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015509
BRD-K31644794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00623
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12845
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5576
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5571
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34373
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986075
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6523
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00661
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Christianson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982313
BRD-K13761649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84022
A549_MLN8054_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193993
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7423
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41604
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64621
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42793
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4582
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23288
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53616
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33108
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26623
BRD-K15420741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07268
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04454
levodopa_rattus norvegicus_gpl4135_gse43375	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orciprenaline-4831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06196
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905822
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430895
Obsessive-Compulsive Disorder	DisGeNET Gene-Disease Associations	1.0	null
A549_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141787
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.46873
alpha-estradiol-1151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8451
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05206
STAT3	ChEA Transcription Factor Targets	1.0	null
NCIH2126	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39374
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.90064
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_4_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-422a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31197
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61796
ticarcillin-5829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153242
BRD-K05777604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41081
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5418
BCPAP	GDSC Cell Line Gene Expression Profiles	-1.0	-2.02329
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48996
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.48539
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Amnion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914589
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83203
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25807
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171311
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.226
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5221
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.46939
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216461
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9739
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993477
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.42
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0185
BRD-K61029307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83808
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66473
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGM2_KD_GSE23702_716_human_NB4 cells, 72h ATRA-induced differentiation	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1822
Recruitment of mitotic centrosome proteins and complexes	Reactome Pathways 2014	1.0	null
NALM6	CCLE Cell Line Gene Expression Profiles	1.0	1.37125
Esophageal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14723547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82136
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.317
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88942
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-1.16583
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39362
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48087
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911983
K562_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129292
nalidixic acid-2336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.768298
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188407
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCC1806	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cloperastine-3710	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
JUND	ENCODE Transcription Factor Targets	1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360754
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BL5711 (AZI1)	NURSA Protein Complexes	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81163
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08196
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40111
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056547
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67122
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1141
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bardet-Biedl syndrome 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14457
membraneless organelle assembly	GO Biological Process Annotations 2025	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_GSK-LSD1 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018283
A549_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202387
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06427
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36257
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61444
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4694
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7743
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69515
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.67755
valproic acid-6199	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.025
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KYSE150	CCLE Cell Line Gene Expression Profiles	1.0	1.46909
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343992
Preeclampsia_Placenta_GSE4707	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45164
TCF3	ENCODE Transcription Factor Targets	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27279
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163318
BRD-A21524347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27223
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05073
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7879
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06089
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3707
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
COR-L279	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79631
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32884
MCF7_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139938
MCF7_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133026
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05871
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.692296
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0819
natamycin-7167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31663
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20135
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8203
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73386
BRD-K22189453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18175
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01541
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38404
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8-MG-BA	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53797
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155579
nitrofural-5321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sulfanilamide-3449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40035
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999784
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.37409
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40842
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49518
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64567
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173685
GSE149075_8_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE66014_0_v_1_perhexiline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4807
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
A549_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160713
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84221
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242143
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09361
BRD-K45621617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0807
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55506
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.29377
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09024
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10456
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412799
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32913
methylprednisolone-7137	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38472
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34556
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133433
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49558
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56212
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46528
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4167
A549_Luminespib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015524
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K00323141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45594
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
valproic acid-6974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6373-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64254
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982672
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMR-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.17794
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151126
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Megasporocyte nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64259
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81275
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54184
NCIH1299_LUNG	CCLE Cell Line Proteomics	1.0	2.98335
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81855
parthenolide-2885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23956
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514395
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80332123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51301
BRD-K70875838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57171
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.053078
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NY	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07908
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12584
ZUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38237
GCT	GDSC Cell Line Gene Expression Profiles	-1.0	-2.17279
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96039
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18187
A549_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184639
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890368
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09112
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88366
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K65166009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42836
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-150	GDSC Cell Line Gene Expression Profiles	1.0	2.71554
GSE131649_4_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Ivosidenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141601
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.631
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11232
BL508 (BRE)	NURSA Protein Complexes	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852655
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64883
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4237056-Table1.PDF-15-SATB2_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17182
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0927
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05165
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930105
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95396
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30638
LCLC103H_LUNG	CCLE Cell Line Proteomics	1.0	2.99233
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07673
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6885354__F4	PFOCR Pathway Figure Associations 2024	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204407
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
Midbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.167
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853738
106_ACTL6A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.595353
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72053
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867286
clindamycin-5815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.074
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6234
A549_Pracinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117875
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-1.03494
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4933
Mitotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
BRD-K70408591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20718
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0645
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3189
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.2981
MELK_knockdown_150_GSE32873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.49299
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBGCP4	Pathway Commons Protein-Protein Interactions	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25619
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857593
r7 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31936
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3476
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ES8	GDSC Cell Line Gene Expression Profiles	1.0	1.56761
BRD-K54453373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01611
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48383
Sarcoma_SARC_TCGA-IE-A4EI-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54379
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.80482
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K54686062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64334
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71871382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14084
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33393
K562_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167956
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34435
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAB3A_KO_GDS2483_700_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K70286959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77925
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98673
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO679	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91109
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LB1047-RCC	GDSC Cell Line Gene Expression Profiles	1.0	1.46124
Lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EB-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118606
gemfibrozil-5069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47368
MZT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K43017905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47016
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.42676
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70542
trifluoperazine-7420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3422
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63389
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24198
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
7q11.23 duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932045
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47896
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265925
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45703
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34637
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15076
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral hemisphere lipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39086
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839098
JURKAT	BioGPS Cell Line Gene Expression Profiles	1.0	2.02988
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.06372
Centrosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58267
nordihydroguaiaretic acid-6983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K37770214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37155
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HLF_LIVER	CCLE Cell Line Proteomics	1.0	3.59974
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29945
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58428
teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16236
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.875
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303387
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06346
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958721
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7098
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15387690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09434
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21824
GSE158834_10_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.75218
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50972
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46305
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31977
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGROV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.46939
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18756
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5963 (RAF1)	NURSA Protein Complexes	1.0	null
Mst2 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75539
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Histone H3-K14 acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903256
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38506
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43552
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75311902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58833
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1052
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04007
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1219
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872454
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68764
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28044
mexiletine-2364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64665523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03631
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.16518
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959008
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01527
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01688
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell cycle	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12439
GSE169155_1_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77853
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58233
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8311
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25387
NCI-H524	GDSC Cell Line Gene Expression Profiles	1.0	2.32378
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39912
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09711
BRD-K05940224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03022
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6983
GSE158834_1_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14691
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
morantel-7250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71177762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34969
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03291
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851958
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2251
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1627
mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0185
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39912
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27423
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5315
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25304254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5052
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.75133
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELA	BioGPS Cell Line Gene Expression Profiles	1.0	1.15192
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2337
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982313
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58506
sulfacetamide-1695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09719
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15677
MISP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89755
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22189
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54905
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20555
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958156
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1552
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982741
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33297
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965506
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00213
H9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051129
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.05105
Intrahepatic cholestasis of pregnancy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64145
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
praderwilliangelman	GeneRIF Biological Term Annotations	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925701
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6725
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2977
PMC6617737-13059_2019_1747_MOESM1_ESM.xlsx-Table_s7_szDMP_OLIG2-Unnamed_23_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
microtubule binding	GO Molecular Function Annotations 2015	1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Resveratrol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158044
BRD-K21743103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38339
A549_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163694
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66355
CRCGN016_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.66425
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1707
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A6UC-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9804
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.127
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-tubulin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
N2 (ESCO2)	NURSA Protein Complexes	1.0	null
BRD-K31584969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35946
Necrosis	CTD Gene-Disease Associations	1.0	1.5619
wortmannin-6959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Meiotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9328
Schizophrenia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967868
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3129
droperidol-5690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22925
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25639
NELFA-20434984-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43846
A549_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194616
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88089
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985561
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26972
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06926
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07548
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54184
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998037
STAT1	ENCODE Transcription Factor Targets	1.0	null
BRD-K76921877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38035
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13223
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule nucleation	GO Biological Process Annotations 2023	1.0	null
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.861677
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K88836117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13728
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47903820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98504
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930103
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44087
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39006
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59448
MZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74496
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XM-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11652878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55716
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
centrosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957247
Corpus callosum lipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15314
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3428-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
drofenine-3455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55535
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17167
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28254
Primary autosomal recessive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
AH-23848-6903	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97975
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K02066524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04837
A549_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130123
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23572
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19597
cetirizine-2468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K60267900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05527
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26532
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
located	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09305
BRD-K94962552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71609
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7758
CRCGN014_HEPG2_3H:D24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02505
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BRD4770_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0256916
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.834651
Smith-Magenis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH650_LUNG	CCLE Cell Line Proteomics	1.0	2.14111
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944357
Prestwick-864-3333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18344
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1615
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41064
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25801
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84836
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61586
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7155
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32699895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56871
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hMPV_72Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.931005
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22984
ZNF384	ENCODE Transcription Factor Targets	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0515
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_PFI-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106958
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16322
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44226
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53241408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35198
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92413
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958156
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0402
GSE158834_11_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90603
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25961
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11356
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.93297
gammatubulin	GeneRIF Biological Term Annotations	1.0	null
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995609
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
flavoxate-7405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.53089
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867392
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38031
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.14782
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97431
cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK115	CCLE Cell Line Gene Expression Profiles	1.0	1.46819
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825209
BL2032 (RFWD2)	NURSA Protein Complexes	1.0	null
scales	GeneRIF Biological Term Annotations	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6129
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017058
BRD-K60255752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79345
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34054
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32162
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K33462260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32418
BRD-A25243629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3825
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90025
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06323
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177091
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16337
SFPI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K77547131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27255
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.996816
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18227
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7421-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78788
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889667
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881822
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.256
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18756
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838357
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8791942-41398_2021_1766_MOESM10_ESM.xlsx-UniqueTD_NT_LPS_NT_LTA-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844804
Nebenkern	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.893346
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23995
Centrosome maturation	Reactome Pathways 2024	1.0	null
HUNS1	CCLE Cell Line Gene CNV Profiles	1.0	1.46447
BRD-K87213231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96237
A549_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033659
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.68363
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969963
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33031
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.95902
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66351990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17972
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1891
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Belinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019802
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01016
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43282617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15856
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.656
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.825247
ribavirin-6018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74662
PMC3189923-pone.0025991.s001.xlsx-CENPB-Unnamed_1_CENPB	Rummagene Transcription Factor Associations 2026	1.0	null
telenzepine-2388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.418
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89772
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-638	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cytoskeletal part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86484
A549_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192131
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28357
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24353
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK5RAP2	Pathway Commons Protein-Protein Interactions	1.0	null
A549_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138365
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30261
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6893
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19115
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50232
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04713
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
SEPHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2078
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851814
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10778
BRD-K64345025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96189
BRD-K31748787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98673
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03896
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59328
K562_Fedratinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181824
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392072
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13346
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04234
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K77834935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66164
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49817
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13978
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83573
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97515
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3744
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76269
subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.40202
CMK86	CCLE Cell Line Gene Expression Profiles	1.0	1.70924
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDKN2A	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21291
cell part	GO Cellular Component Annotations 2015	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15137
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64885
A549_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017131
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-0.985334
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19586
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93691
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3719
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170341
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.06042
A-Vietnam-1203-2004(H5N1)_2day-TNFRSF1BKO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84434
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dyscalculia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.592
Perturb_7226_KO_CDK8_SRP271652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863731
non-membrane-bounded organelle assembly	GO Biological Process Annotations 2023	1.0	null
KYSE30_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.03191
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13071687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38473
BRD-K05465626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75664
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10525
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.517583
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44407
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82757
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951234
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98149
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
MG-262-7068	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NEDD1	NURSA Protein-Protein Interactions	1.0	0.571353
bisoprolol-1287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sanguinarine-4168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.735
hsa-miR-2054	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K65796649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84196
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412999
cellular_component	GO Cellular Component Annotations 2015	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
M Phase	Reactome Pathways 2024	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02663
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCIH2444	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13429
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3244
securinine-2729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33616
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67141726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41959
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01228
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37203
sertaconazole-3550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124132
HIF1A_01_224	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65758
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1137
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0061
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK3_knockdown_110_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.71259
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14204
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD-16-KY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250146
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0762
planum polare, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.837718
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93357
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02248
SF3B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00676
Central precocious puberty	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188189
A549_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179781
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205963_0_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909234
TUBGCP6	NURSA Protein-Protein Interactions	1.0	0.418027
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K70861166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12951
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Thalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175679
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34982
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8093
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34113
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835517
A549_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150315
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183162
MCF7_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210401
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15575
7734_SEC13_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.571294
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992516
TWF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00102
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24081812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05277
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43262
STAT5A	ENCODE Transcription Factor Targets	1.0	null
troglitazone-6949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-378c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-A35871558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95213
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74323
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55061
quantitated	GeneRIF Biological Term Annotations	1.0	null
microtubule binding	GO Molecular Function Annotations 2023	1.0	null
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08932
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6161
A549_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197134
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.14681
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06093
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10964
hsa-miR-301a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
EB-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06867
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27368
brain	HPA Tissue Gene Expression Profiles	1.0	0.983237
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0319
A549_Cerdulatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213023
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05576
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917137
controlling	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75023
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01593
lincomycin-7411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
29-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12539
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	2.24878
NPTXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2449
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08662
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2945
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45404
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59146
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Panobinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0113999
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04899
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03537
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140607
BRD-K86986466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.702
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3051
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836769
hsa-miR-4265	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-dORF6_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.961148
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858715
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51385
Arp2/3 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.29
CRCGN016_MCF10A.TP53.M_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16391
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.851255
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151689
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-U02532950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80579
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HY-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51535480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79283
GSE132313_1_v_0_fosl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0632
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05795
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.09206
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-542-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99828
GATA4	ChEA Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.913064
domperidone-5701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3165	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3611
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.2767
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6617737-13059_2019_1747_MOESM1_ESM.xlsx-Table_s7_szDMP_OLIG2-Unnamed_22_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
microtubule organizing center	LOCATE Curated Protein Localization Annotations	1.0	null
spindle assembly	GO Biological Process Annotations 2025	1.0	null
medrysone-3603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RL952	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83039
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32869
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K65494150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16067
gamma-tubulin binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12934
microtubule organizing center part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214212_3_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93508
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46984
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061451
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05749
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929774
H4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.77143
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21668
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4981
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13859
GSE61117_0_v_1_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04441
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZT2B	NURSA Protein-Protein Interactions	1.0	0.112527
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.747
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.05423
A549_AR-42_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157478
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46311
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26697
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.950632
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-378i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886535
PC-14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76448
KU812	CCLE Cell Line Gene Expression Profiles	1.0	3.19563
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41328
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80244
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45258
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17784
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.982868
Right atrial isomerism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
depudecin-982	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
microtubule organizing center part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30937
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20842
Primary Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32342
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173201_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12407
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2412
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923997
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868462
BRD-K76015448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17044
Centrosomal corona	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10451
BRD-K76197651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0546
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874822
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9944
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55724
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45099
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9328
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20333
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34979
fenspiride-7298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1579
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34604755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05307
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49232
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00533
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.646
STUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48377
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05804
Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7728
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10115
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882536
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830137
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-45	GDSC Cell Line Gene Expression Profiles	1.0	1.72728
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46522
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1468
hsa-miR-4789-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
clozapine-4453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892325
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cell Cycle	Reactome Pathways 2024	1.0	null
LAMA-84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.736243
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoblast	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7099
metoclopramide-2315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4295	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163771
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JK-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Ruxolitinib_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134216
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881428
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991581
levodopa	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03069
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18612
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
A549_Dacinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117486
CREB1	ENCODE Transcription Factor Targets	1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6616
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.797462
BRD-K43435656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19833
K562_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137115
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1846
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2729
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25863
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12106
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microtubule organizing center	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.386
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71837
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80279
New mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.588
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25396
Silver-Russell syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30104
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental coordination disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
A549_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150993
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-257	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25563
A549_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157255
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33633
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K12743035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05977
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10131
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31056
trichostatin A-7555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57879743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08274
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4559
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.935854
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44034
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957247
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84777
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hydralazine-2349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Chromosome Deletion	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01303
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30349
A549_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224315
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4265
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955807
BRD-K19310540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2586
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypoxia_Astrocyte_GSE4483	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.792876
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule organizing center	GO Cellular Component Annotations 2015	1.0	null
A549_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0331441
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12432
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984041
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04909
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_4507_KO_Farp1_SRP374413	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
genistein-6952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96970199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29592
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241887
GSE158834_11_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7754
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
microtubule minus-end binding	GO Molecular Function Annotations 2023	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42107
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22315
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.952968
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5081
BRD-K76114616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18539
8842_TFCP2L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.686137
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17806
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18753
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.852
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9228
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-29-PZ41_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204633
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03312
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883976
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8658
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06177
TGFBR2_knockout_294_GSE36778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.31775
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26714
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06189
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL4287 (PPP2R5A)	NURSA Protein Complexes	1.0	null
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06768
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22153
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04328
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.851044
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359056
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60855
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74705119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38704
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828622
MXI1	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
centrosome	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31445
EBC1	CCLE Cell Line Gene Expression Profiles	1.0	2.02167
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35799753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1489
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995152
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.47514
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9264
DCP1A	ChEA Transcription Factor Targets	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.457487
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4341
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894797
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K40917447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04774
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05792
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02346
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37957
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04253
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4486
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4601
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893061
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45817496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53941
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00001
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970019
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8277-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381999
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60136
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
diclofenac-5861	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.82024
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32433
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10343
p2 part of the zona limitans core population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11323
Caudolateral nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
hsa-miR-378f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE99687_3_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059832
GSE117643_1_v_0_irx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.00799
pimethixene-7426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE161846,GSE161849_1_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39841
A549_MLN8054_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145442
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93359
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841485
BRD-K23997756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04133
BRD-K83270266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01167
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05739
BL4938 (TRIM56)	NURSA Protein Complexes	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15108
CRCGN011_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76725
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13057
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34225
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxycycline-7195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834998
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892863
protein binding	GO Molecular Function Annotations 2015	1.0	null
mephenesin-2342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
CRCGN016_MCF10A.TP53.M_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30724
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
microtubule polymerization	GO Biological Process Annotations 2023	1.0	null
Mitotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19314
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177681
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86728
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21058
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4372
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
KLE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58033
Lung squamous cell carcinoma_LUSC_TCGA-33-4538-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02633
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.60149
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.95499
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.14564
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955416
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38615358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07743
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
gamma-tubulin complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
A549_Lapatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014621
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08496
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00218
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
UB-90-TA33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231741
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5595
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.908356
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826756
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60333
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35455
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10648
guanfacine-2634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842056
HS578T	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.36469
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958156
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980774
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1515
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587467
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843948
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33118
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30153
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spindles	GeneRIF Biological Term Annotations	1.0	null
Clumsiness - Motor Delay	DisGeNET Gene-Disease Associations	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03713
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95193
Sarcoma_SARC_TCGA-QQ-A8VF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2052	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8411
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45768
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2273
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.469
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27286
A549_Rigosertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155851
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87171
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ABCA1_OE_GDS2303_189_mouse_LDL receptor-deficient livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
Primary microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
MCF7_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147842
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00144
JHOS2_OVARY	CCLE Cell Line Proteomics	1.0	3.14958
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15137
BRD-K80290360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.601
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00649
BRD-K91998226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31369
Centrum semiovale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93933
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159302
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364597
KYSE-150	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K12111274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47381
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2453
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MW-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CAL-33	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51019
A549_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012048
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
K562_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146343
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259106
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97301
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01805
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.68093
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41112
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
A549_MC1568_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019394
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37945
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93125
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.541
A549_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0271715
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59826
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67478255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12697
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94924
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325069
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949392
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.391
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84074
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.87317
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97502
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912725
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0104274
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377369
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17182
BRD-K75844518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.785
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152558
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63126
hsa-miR-378d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K01467488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27667
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12092
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	3.31354
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77367
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54697
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29261
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.458
Intracellular signaling and cell migration supercomplex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69763
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33572
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.015
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
demeclocycline-4728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.24683
Sarcoma_SARC_TCGA-K1-A42W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86621
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-03-PW00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326863
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76811
CDH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12151
cancer	GWASdb SNP-Disease Associations	1.0	1.29323
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16832
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39251
IST-MES1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.74542
1-alkyl-2-acetylglycerophosphocholine esterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-378	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07311
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019167
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0097416
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12103
A549_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192076
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21289
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315651
BRD-K98953112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5692
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53739
hsa-miR-769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
17683608-TableS2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4769-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20758
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06908
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853774
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AURKB_knockdown_92_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50183
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	1.68278
BRD-K52124788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10119
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62305
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	2.21194
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201881
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9805
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KU1919_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.7792
Interphase microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.518
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17721
ZBTB33_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40234
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05926
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01592
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09546
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04058
BRD-K90127324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74271
A549_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154883
loxapine-5293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70284
HOXB4	ChEA Transcription Factor Targets	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mitotic	GeneRIF Biological Term Annotations	1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871027
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.50661
formation	GeneRIF Biological Term Annotations	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02877
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29271
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336376
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16206
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406865
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831035
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4322	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
poles	GeneRIF Biological Term Annotations	1.0	null
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71607
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23711
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.46603
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06185
CTCF	ENCODE Transcription Factor Targets	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323076
fenbendazole-2360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46941
Spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16967
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6162
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04469
BL5634 (AKAP12)	NURSA Protein Complexes	1.0	null
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963338
CRCGN016_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36437
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.911673
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305547
Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214308
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.36157
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30059
including	GeneRIF Biological Term Annotations	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34146
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44012257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45771
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242904
NR3C1	ENCODE Transcription Factor Targets	1.0	null
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04891
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.8525
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.403
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
a-USP9X (USP9X)	NURSA Protein Complexes	1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8553
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.88385
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEXN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59831227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10087
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1155
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primaquine-1343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10397
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.322
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93491540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63199
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6397
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92016
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06258
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	0.884737
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65578
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27133
BRD-K56572622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12106
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86707
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853579
CDK9_knockdown_104_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.60084
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40961
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.822353
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45162
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05378
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38342
CHD1	ENCODE Transcription Factor Targets	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52185
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859627
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9892
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAOV4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00628
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856525
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921993
genomic	GeneRIF Biological Term Annotations	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84043
5253409-844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.072
hecogenin-3457	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23995
intracellular organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
bufexamac-7413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46696
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22748
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86599
BRD-K94145457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2628
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8902
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838208
A549_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114189
FOXO3	ChEA Transcription Factor Targets	1.0	null
BRD-K69808609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75079
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3003
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.861664
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8
gamma-tubulin binding	GO Molecular Function Annotations 2025	1.0	null
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44162
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08448
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04307
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.186
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Entacapone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149617
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87675
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06768
SARS-BatSRBD_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40728
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16892
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2136
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18852
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11183
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57042334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16419
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0758
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3734
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
behavior	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191418
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	0.876563
SMARCA4	ChEA Transcription Factor Targets	1.0	null
BRD-K13402127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17649
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05975
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8604
supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.448441
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30224
MCF7_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00964567
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13828
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00604
EBF1	ENCODE Transcription Factor Targets	1.0	null
BCB000040-7493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71119
A549_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232311
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48366
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gamma-tubulin complex component protein	InterPro Predicted Protein Domain Annotations	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_PHA-680632_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141047
UMRC6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50592
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897772
psychological	GeneRIF Biological Term Annotations	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4668
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2215
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid-1639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mitotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.785
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6434
CRCGN015_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5961
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53834
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05257
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22462
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15431
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39925250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98302
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853729
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73405
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81323
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54522
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10434
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	2.162
hsa-miR-4475	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Plasma membrane	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.64036
thioguanosine-6643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43822
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0342
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
trichostatin A-6340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.35366
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838671
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37866
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20293
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25387
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.63754
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.22394
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	1.13214
BRD-K16411174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11157
A549_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203433
BB-20-UU03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290214
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31197
LM-1685-253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K84266230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35351
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6287
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fasudil_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230035
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A51B-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFE184	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49025
BRD-K86232678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63224
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57604
hsa-miR-4318	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33022
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4968
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04528
BRD-K46085646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11774
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A02927672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54163
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
astemizole-4471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6161
Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.27067
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859668
gamma-tubulin ring complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53121826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45239
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
etanidazole-6211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01723
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12933
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143651
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.831825
MYCN	ChEA Transcription Factor Targets	1.0	null
A549_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184977
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
etamivan-7021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863312
A101D_SKIN	CCLE Cell Line Proteomics	1.0	2.24882
Perturb_15684_OE_Tlr7_SRP155370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.62529
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834914
CBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06881
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
gamma-tubulin complex	GO Cellular Component Annotations 2015	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15654
cytoplasmic microtubule organization	GO Biological Process Annotations 2025	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.62013
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915894
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.95919
GSE98973_3_v_0_sorafenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151221
A549_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134555
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.17959
CRCGN017_MCF10A.WT.HP_24H:N18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1502
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.457
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.808129
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.983237
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-A96308662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47402
K562_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145863
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49215099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62692
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36156445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90011
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162694
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70357895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85397
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55506
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35939
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.976234
E2F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tiletamine-6516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982299
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50471
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20396
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30414
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835051
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01592
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.4125
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29125
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.97976
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924002
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55372
MCF7_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126647
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nipa2	GeneRIF Biological Term Annotations	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10366
BRD-K62624148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03494
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47959
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03915
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09812
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_2015_KO_Slamf9_SRP199215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.82486
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10562
OLIG2	ChEA Transcription Factor Targets	1.0	null
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.86166
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1703_LUNG	CCLE Cell Line Proteomics	1.0	4.08333
points	GeneRIF Biological Term Annotations	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAUS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.909
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2981
A549_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0280458
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04441
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K19590405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15418
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4335
hsa-miR-522	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
A549_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151298
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35155
Recruitment of NuMA to mitotic centrosomes	Reactome Pathways 2024	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.3659
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.02634
A549_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195095
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830137
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22834
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79835
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15802_KD_METTL3_SRP373116	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36190163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04161
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57968
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24242
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0319
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72013
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26677
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66537
K562_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160903
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6672
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408139
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80368
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
letrozole-4824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
praderwilli	GeneRIF Biological Term Annotations	1.0	null
BL5030 (CHD6)	NURSA Protein Complexes	1.0	null
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.80871
gamma-tubulin large complex	GO Cellular Component Annotations 2015	1.0	null
BRD-A23193246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93678
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1219
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.64281
GSE131565_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dimethylfraxetin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
BRD-K85513726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51011
GSE182680,GSE182683_0_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chromosome 22q11.2 microduplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2136
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881118
HOXC9	ChEA Transcription Factor Targets	1.0	null
valproic acid-6999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.130221
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04650671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4974
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.188
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00791
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.9151
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.62504
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
g2/m transition of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83775
A549_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213119
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04182
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04197
BRD-K95443593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10992
BRD-K01853388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75216
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.82758
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.61404
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2875
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41043
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94921
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24329
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.00494
BL7526 (SOS2)	NURSA Protein Complexes	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02225
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.418
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	1.01393
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary ciliary dyskinesia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01746
Central nervous system lipoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20138
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2A_Deficiency_GDS5084_271_mouse_DN2 thymocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46768
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95114614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27054
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02841
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965074
BRD-K46961295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63867
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0064
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dyclonine-7423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63599
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.885
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173069
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36302
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31288
ZNF274	ChEA Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82425094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33846
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14114
A549_Tucidinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015803
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
sclc21h	HPA Cell Line Gene Expression Profiles	-1.0	-1.07763
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20838
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10778
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
A549_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178356
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2643
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1894
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84533
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10068
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6603
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.199993
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1081
BRD-K74948793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37485
8665_TAF5L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.653871
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.6532
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02885
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
Aster	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02791
MZT2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mitotic Prometaphase	Reactome Pathways 2024	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56767
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65913
CBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18791
cell cycle g2/m phase transition	GO Biological Process Annotations 2015	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.26
thioguanosine-4989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08864
BRD-A33119430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07647
U-266	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1139
carbenoxolone-3353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mitotic spindle assembly and cell cycle regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31071
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66964
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20981
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283392
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29583
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98986
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell division site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
cytoplasmic microtubule organization	GO Biological Process Annotations 2023	1.0	null
A549	CCLE Cell Line Gene CNV Profiles	1.0	1.37472
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01138
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839624
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15789
gamma-tubulin large complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35944
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.974884
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06422
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30209
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17152303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04749
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70814
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74678
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57882
A549_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216019
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95043
A549_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142438
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6764
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	2.50951
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3839
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58921
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02275
hydroxyprogesterone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60539
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051129
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843671
Autism	DisGeNET Gene-Disease Associations	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82101
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41893
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4395
centrosome	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855873
NCI-H322M	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922067
G2/M Transition	Reactome Pathways 2014	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.506
GSE246576,GSE246826_0_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143504
trifluoperazine-1004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10010414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71331
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.63463
JURLMK1	CCLE Cell Line Gene Expression Profiles	1.0	2.28096
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223331
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2A_KO_GSE43224_679_mouse_DN2 cells from WT and E2A-deficient murine fetal thymi	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.950369
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887117
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210505_0_v_1_sox1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382455
trifluoperazine-1165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19742
angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26734
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983205
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90144
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.24699
A549_Panobinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00985069
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80144
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11356
BRD-A23434937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59987
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35589
A549_RG108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197796
microtubule nucleation	GO Biological Process Annotations 2015	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.359
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0098
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0201
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67879
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22579
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38969544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18021
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34241
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33347
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
MCF7_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0113155
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9422
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4690-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.099
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12432
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.7221
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2109
K562_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146858
MEC2	CCLE Cell Line Gene Expression Profiles	1.0	1.51204
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BMS-911543_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196126
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46854
A549_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187439
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4291
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78814
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20645
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
Subparafascicular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29104
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.95731
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0246
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159068
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15321
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
A549_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.029571
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320731
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01818
BRD-K66841501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31159
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52904
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172714
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8146
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9736
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2972
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07572
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272305
BRD-K27263328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59511
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41033
BRD-K06532738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36063
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943672
trichostatin A-4526	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pt-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15321
MCF7_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141933
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.26941
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25975
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40121
hsa-miR-379	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38444
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30745
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16476
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33288
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BL-ATM (ATM)	NURSA Protein Complexes	1.0	null
A549_Pracinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00930443
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
K562_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236924
PMC10558344-mmc1.docx-3-ZNF670_ZNF670	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.03855
BRD-K98201103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47133
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2192
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7671_KD_NBAS_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.69946
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.266
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.978
Mitotic G2-G2/M phases	Reactome Pathways 2024	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
A549_Navitoclax_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119736
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04796
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39173
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-tubulin ring complex	GO Cellular Component Annotations 2015	1.0	null
Developmental Disabilities	HuGE Navigator Gene-Phenotype Associations	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.03043
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06574
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microtubule polymerization	GO Biological Process Annotations 2025	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.47606
Centrosome maturation	Reactome Pathways 2014	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7653
SC-58125-254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07345
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.273
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00148
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67923
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44921
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell Cycle, Mitotic	Reactome Pathways 2024	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10589
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.297276
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24045
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70896
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29709
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47476
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234988
tubulin binding	GO Molecular Function Annotations 2025	1.0	null
A549_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227005
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K14889526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33293
BRD-K79152256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46965
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_BREAST	CCLE Cell Line Proteomics	1.0	2.38225
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
homochlorcyclizine-7417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34763
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.671
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16589
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43485
u251mg	HPA Cell Line Gene Expression Profiles	1.0	1.62619
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24552
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.979759
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.219
A549_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162993
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14078
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.907
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35016
BRD-K68328788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34288
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01696
Perturb_5559_KO_Wdr26_SRP212064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.8994
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3143
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885268
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86589
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22315
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.87977
triamcinolone-7192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A87325732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08133
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29975
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10343
A549_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164687
diphenhydramine-7318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87441
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862828
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45323
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Centrosome	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.386
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1788
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_GSK-LSD1 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128502
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0832
BRD-K46120925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03958
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03064
SETDB1	ENCODE Transcription Factor Targets	1.0	null
r74	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.26629
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867392
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945285
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866309
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6166
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1138
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8171
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915216
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
gsk3beta	GeneRIF Biological Term Annotations	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64625
H2461	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Miller-Dieker lissencephaly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23252
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7753
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308558
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03828
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.377
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29229
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87109
BRD-A26222320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5249
3869_HNRNPK_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.565353
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3563
capsaicin-5673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38256
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ketanserin-3209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838582
BRD-K27320944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29154
tubulin binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K81510336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48775
PMC7782698-41467_2020_20367_MOESM9_ESM.xlsx-Student_s_t-test_BP1_ILK_GFP-Gene_names_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0717
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25669
LGALS3BP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973463
Poisoning	CTD Gene-Disease Associations	1.0	1.2393
TAF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_ZM 447439_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160091
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37388
NUDHL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78892
CCNT2	ENCODE Transcription Factor Targets	1.0	null
BL8216 (PHRF1)	NURSA Protein Complexes	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2423
JL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40934
hsa-miR-3138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
A549_EED226_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202912
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29231
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hyoscyamine-2108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16829
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54872884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1686
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57757
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
spindle assembly	GO Biological Process Annotations 2023	1.0	null
K562_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161776
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4727-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874555
TUBGCP4	NURSA Protein-Protein Interactions	1.0	0.399436
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48029
Choline	CTD Gene-Chemical Interactions	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853842
A549_AR-42_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196196
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oculocutaneous albinism type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964101
ZBTB33_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17909
BRD-K44004565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05284
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	1.42365
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.44692
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28026
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prader Willi and Angelman syndrome	WikiPathways Pathways 2024	1.0	null
centrosome	LOCATE Curated Protein Localization Annotations	1.0	null
MCF7_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143371
S-propranolol-3523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.89546
Acute Myeloid Leukemia_LAML_TCGA-AB-2816-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8682
BRD-K72915114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13999
gamma-tubulin large complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70705
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880637
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3065
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
betonicine-6063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.07176
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00163
STOCK1N-28457-6864	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.122
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cyfip1	GeneRIF Biological Term Annotations	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22082
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30028
BRD-K78647367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45268
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PML	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.04867
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204588
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13417
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5168
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894543
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24564
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49161
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49484
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30562
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16881
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830746
GSE147626_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7582
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2282
SERPINH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1435
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11978
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11632
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96752
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_EED226_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144931
A549_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014165
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2772
K562_Entacapone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182776
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1239
ZBTB33_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule nucleation	GO Biological Process Annotations 2025	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0961
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06711
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94544
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167059
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2534
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00562
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77509
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79433629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20625
BRD-K54850621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99663
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29562
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
16,16-dimethylprostaglandin E2-6562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05319
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.793
PRICKLE3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01573
RELA	ENCODE Transcription Factor Targets	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09087
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50665
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.23157
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00755
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830137
Stipule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.153
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-1126-SM-48TZY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844559
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	205.938
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25352
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16593
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38244
A549_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162207
1141_CAAP1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.680672
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10422
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04666
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855164
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236003_0_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019522
Cell Cycle, Mitotic	Reactome Pathways 2014	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061747
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0843
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.661
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32073
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_G007-LK_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164265
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04714
TEAD4	ENCODE Transcription Factor Targets	1.0	null
KLF15_Deficiency_GDS2687_648_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8702
SIN3A	ENCODE Transcription Factor Targets	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.52864
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6866
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_8_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55109
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69266
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51553
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1159
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44251
BRD-K84792586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06404
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BL443 (EP300)	NURSA Protein Complexes	1.0	null
A549_Ruxolitinib_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207757
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00547
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01484
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931483
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42334
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01497
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
acetylcholine-gated channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.459
A549_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015734
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34509
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33675
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58509
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77087
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.845915
BRD-K01250897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37476
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Procentriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64186
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
A549_FLLL32_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249699
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76541957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07931
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974283
MCF7_Luminespib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00881049
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73187
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4067464-onc2013378x3.xls-Sheet1-Supplementary_Table_1_Top_1000_E2F4_Chip-Seq_targets_that_are_repressed_by_p53_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.216
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38207
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.643743
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3228
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23351
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FAM221A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34117