association	dataset	threshold value	standardized value
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46811
Trachea-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.280884
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34135
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00734359
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15264
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49942
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968255
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1127
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38341
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4733
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15105
LP1	DepMap CRISPR Gene Dependency	1.0	2.97752
Spleen	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.45901
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97479
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Azacitidine_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163028
LK2_LUNG	CCLE Cell Line Proteomics	1.0	4.67921
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.932044
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.753
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09085
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056199
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.327
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01084
Inflorescence stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	13.689
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16794
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22326
CHP126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84702
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961662
Perturb_7066_KO_Lrpprc_SRP110979	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.6886
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86796
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GE-25-DQ65_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272401
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39216
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14893
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-MXE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.852745
Sarcoma_SARC_TCGA-HB-A2OT-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAL1_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209274
Perturb_15036_KD_Ctcflos_SRP311201	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.93685
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10578
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42008
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Blood 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	13.004
Hepatitis C virus genotype 1b (isolate Con1)	Virus MINT Protein-Virus Interactions	1.0	null
Perturb_13752_KD_CREBBP_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.61083
Lidocaine (hydrochloride)_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0238176
DFCI024	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82735
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78252
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.218
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1502
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857905
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8125
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967947
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10228
GTEX-X5EB-1726-SM-4E3J7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0859
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU182	DepMap CRISPR Gene Dependency	1.0	3.71824
K562_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179148
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21991
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0211
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65274
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914166
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.07579
Bone_Marrow-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	1.03549
Perturb_2359_KD_TRIM25_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.10953
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49067
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal bone structure	IMPC Knockout Mouse Phenotypes	1.0	null
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.37715
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02068
Tofacitinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95651
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040665
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29806
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190599
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3316
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4233_KO_Pnky_SRP187847	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.2016
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983162
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44341
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64345
MYBL2	ChEA Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58324
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2102
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12731
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15849
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10528
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04578
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.72334
Perturb_2049_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.58075
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26129
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.844988
GSE225083_0_v_1_kras_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0799
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
D425	DepMap CRISPR Gene Dependency	1.0	2.86521
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.59035
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040132
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10289
HCC1806	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35311
DDX56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02165
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97791
A549_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0279151
STAT5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945723
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_9556_KO_IKKa_SRP111864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82201
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8193
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76516
single-organism process	GO Biological Process Annotations 2015	1.0	null
Perturb_1446_KO_Tmem173_SRP221603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.97945
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12486367-Supplementary_Data2.pdf-383-MAFB_MAFB	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142094
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936408
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18239
K562_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226824
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45107
HB-75-KT12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219036
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0441
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122239
HC-38-KI38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21137
BB-32-IZ10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636762
KMS21BM	CCLE Cell Line Gene Expression Profiles	1.0	1.90787
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3316
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054392
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289192
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02615
Leading edge of lamellipodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1369
GSE184884_7_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
18974375-TableS5b	GeneSigDB Published Gene Signatures	1.0	null
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.92521
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital disorder of glycosylation type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987585
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.86396
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84519
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1500_BREAST	CCLE Cell Line Proteomics	1.0	3.49541
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43948
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hydroxyurea_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00691897
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31597
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898851
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.65556
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10704
Perturb_12073_KD_Tgfb1_SRP067296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.83587
DUOX1	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968324
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914066
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21079
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07352
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46181
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46144
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27689
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12775
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07294
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858804
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6438015-13148_2019_651_MOESM7_ESM.xlsx-Sheet1-Table_S2_Genes_exhibiting_both_significantly_increased_promoter_methylation_and_significantly_lowered_expression_in_CRISPR_TET2-KO_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08147
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08483
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.04086
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969458
G-401	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42237
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42613
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK10_knockdown_116_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.33104
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35872
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
K562_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258297
GSE111102,GSE111105_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00950433
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910666
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.036
Perturb_12072_OE|KD_Tfap2a|Tgfb1_SRP067296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.56647
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74246
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32481
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34135
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.2984
K562_Ivosidenib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146265
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45752
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FD-29-MM50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332296
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35015
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07349
K562_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195138
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06517
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51644
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JHOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Type 2 diabetes mellitus_Endocrine Pancreas - Islet Cell of Langerhans - Beta Cell (MMHCC)_GSE6428	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.6298
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	0.428142
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01791
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11542
Perturb_7518_KD_TRDMT1_SRP217219	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4994
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.21141
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13857
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48055
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898939
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.16249
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16740_KO_Gcn5_SRP271119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.23028
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8118
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00846
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lateral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Lucanthone_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0124092
FBXO6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TR146	DepMap CRISPR Gene Dependency	1.0	2.17337
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09026
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12850_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.5395
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24866
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4509
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11424_KD_KIF4A_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.88615
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.231432
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90129
A549_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167436
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-00-WA10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335055
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929943
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07351
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52306
ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.223497
TAL1_megakaryocyte_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17292
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22299
Perturb_1057_KO_Bcl9/Bcl9l_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.49485
Perturb_10616_KO_Ttn_SRP136441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.36154
Perturb_7406_KD_HNRNPH1_SRP010280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.48499
K562_Lapatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015428
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03805
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.615873
ME-54-JY76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353794
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515141
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218673
K562_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166486
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959988
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
decreased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FLI1	ENCODE Transcription Factor Targets	1.0	null
K562_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182413
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912255
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06607
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.97
Perturb_16713_KO_Prkab1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.48923
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MEF2A-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.82193
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.5766
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15365_KO_Klf2_SRP064312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.22441
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6959
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58304
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
3978_HSPA5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.560584
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924894
A549_BMS-754807_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013862
Perturb_18606_KD_Lsm1_SRP327180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.93464
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75286
Perturb_8825_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Minodronic acid_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0207503
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41749
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53281
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607546
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytosolic creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
CBX2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90754
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1319
nes	HPA Cell Line Gene Expression Profiles	-1.0	-0.95756
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.153
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-HEK_and_SupT1_up_XBP1s_ATF6-S7_Data_List_of_genes_upregulated_in_both_HEK293DAX_and_SupT1DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32056
K562_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124464
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972606
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
5-Fluorouracil_A498	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0175995
Thioredoxin domain	InterPro Predicted Protein Domain Annotations	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1,4-DHNA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.51
K562_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167018
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFEB	ChEA Transcription Factor Targets	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0232428
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0822
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.00563
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28492
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77746
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64819
9837_WDR70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.604705
HS683	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17505
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50645
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_POU5F1_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22226
MCF7_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141902
SMARCA4	ChEA Transcription Factor Targets	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Perturb_4805_KO_Mapk1_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.30485
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.511355
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43732
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.40469
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2516
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857743
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06144
BB-28-MC54_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357947
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33443
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9761
GSE228619_0_v_1_cdh11_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1125_KO_Myc_SRP168941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.19075
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362732
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42322
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10491
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058124
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05314
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.26
Lidocaine (hydrochloride)_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0197334
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31016
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03851
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6698_KD_ALAL1_SRP214241	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48439
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879683
Liver Diseases	CTD Gene-Disease Associations	1.0	1.09011
Perturb_3232_KO_Pou2af1_SRP293293	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.57668
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906699
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860898
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.74451
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.80479
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924988
bp86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09164
CCNT2	ENCODE Transcription Factor Targets	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mannosyl-oligosaccharide 1,2-alpha-mannosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.798
K562_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160953
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58904
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11808
organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27639
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06834
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530361
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21631
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2465
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CI-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71418
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303198
STAT5A	Pathway Commons Protein-Protein Interactions	1.0	null
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0713
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Norepinephrine (hydrochloride)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0170552
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1006_KO_Bcl9l/Bcl9_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.32718
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92505
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01293
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.865011
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13732
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
K562_BMS-911543_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184095
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B-cell acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
MCF7_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014261
GSE140651,GSE140653_5_v_7_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84249
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44256
Perturb_1680_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.92646
Perturb_6785_KD_USP42_ERP121305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.69715
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GB-57-XV52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340989
SIN3A	ENCODE Transcription Factor Targets	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.870601
K562_Roxadustat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175745
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63927
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1899
Perturb_11199_KD_Scap_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.2578
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22635
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thymus-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	11.8349
EGR1	ENCODE Transcription Factor Targets	1.0	null
POU5F1-18700969-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174118
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59479
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288473
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834093
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00731
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD5_02_48	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59337
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16037
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12077394-giaf035_giga-d-24-00380_original_submission.pdf-13-HMG20B_HMG20B	Rummagene Transcription Factor Associations 2026	1.0	null
17683608-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79282
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03013
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4953
K562_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109842
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.848113
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2015	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03735
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09501
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Prednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162154
superficial stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08834
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387984
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34544
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.338
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824599
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471676
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33162
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
K562_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168171
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04316
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20007
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50495
Perturb_14937_KD_Pnky_SRP053095	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44758
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39216
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31095
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03137
PNGase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.773
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9758_OE_Mbnl1_SRP354130	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19859
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.74536
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25787
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00126
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894159
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52237
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94336
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5205_MRPL21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.578083
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.012
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
DA-10-ZX00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200371
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ID-12-NA84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221092
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92457
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16746_KO_Ly6e_SRP250973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.2743
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
4066_IGF2BP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.618316
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.9982
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922221
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.30045
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Q9WMX2	Virus MINT Protein-Viral Protein Interactions	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60307
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916752
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3NA-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.45991
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830961
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04265
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870436
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0612
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31297
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894987
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5869_KD_Cpsf7_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.13725
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944989
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.90699
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6218
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.66
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64806
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.73777
esophagus	GTEx Tissue Gene Expression Profiles	-1.0	-0.829528
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168797_4_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6787
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00963612
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3697
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829885
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARS-CoV_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.02004
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09327
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4555
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MZ in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05029
STAT1	ENCODE Transcription Factor Targets	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054228
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05393
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intracellular signaling and cell migration supercomplex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23473
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21637
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05334
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31203
CTV1DM	DepMap CRISPR Gene Dependency	1.0	6.01243
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21379
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21973
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35672
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
9972_ZBTB16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.821569
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69151
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13987
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12663
K562_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226609
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982457
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73544
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65066
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15442
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Benztropine (mesylate)_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00797014
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-26a-5p	MiRTarBase microRNA Targets	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMO1	CCLE Cell Line Gene Expression Profiles	1.0	1.6863
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46683
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28101
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143282
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830355
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50058
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977373
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.325
K562_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184231
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02773
TCF12	ENCODE Transcription Factor Targets	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23803
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24042
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	0.996933
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959415
K562_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130602
Pyridoxine (hydrochloride)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0306412
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11606
UMUC1	DepMap CRISPR Gene Dependency	1.0	3.26602
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968324
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13832
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14652
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.090466
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86329
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37333
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855449
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14629
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448557
NCI-H716	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43537
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5030-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22705
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515882
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.473444
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265178
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60978
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1813
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15122
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08326
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13824
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222072
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.77618
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
A 803467	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2362_KD_ZNF581_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.79057
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.69926
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61744
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02943
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_3_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00938
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.7147
TRIM28	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.18454
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33396
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
PMC4790538__F3	PFOCR Pathway Figure Associations 2023	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3624
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10794
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	3.36167
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389455
FD-29-MM50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259568
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46166
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18772
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1202
TAF7	ENCODE Transcription Factor Targets	1.0	null
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051151
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74392
Tofacitinib_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0123002
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02581
MCF7_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155613
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01455
Mean spheric corpuscular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.01549
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7684
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
A4FUK	CCLE Cell Line Gene Expression Profiles	1.0	2.1541
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869027
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92053
increased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44258
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34033
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45285
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07532
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Plasma membrane	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79934
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2670_KD_ZMIZ1_SRP212150	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72228
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32056
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27684
OCIMY7	DepMap CRISPR Gene Dependency	1.0	6.3167
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.10233
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874482
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L2-22581777-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.625
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834703
Perturb_14899_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.63058
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1035_KO_Apoe_SRP197523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.13276
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053477
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06031
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01905
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856457
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01842
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.238068
CORL23_LUNG	CCLE Cell Line Proteomics	1.0	7.04039
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03174
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29504
GSE190555,GSE190557_2_v_3_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12370121-pone.0329101.s003.pdf-2-BATF_1_BATF	Rummagene Transcription Factor Associations 2026	1.0	null
B cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
K562_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172992
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17383
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15815
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SF295_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	4.01991
CREB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32338
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17401
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.64819
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_141_KD_Kdm5c_SRP255034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.30528
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5868_KD_Cpsf6_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.74024
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59631
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Azacitidine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127366
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01111
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898851
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.958002
K562_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171202
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.725352
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052231
Perturb_16579_KO_Crebbp_SRP174041	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08203
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17676
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75597
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.983694
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879011
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5043_KO_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.5033
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29454
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50533
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879496
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130944
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97368
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20029
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39681
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49656
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30537
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846284
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10139
Perturb_12792_KO_Tgfbr2_SRP133892	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.6548
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71687
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051308
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	3.88881
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARH-77 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20543
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19036
BL1730 (SPEN)	NURSA Protein Complexes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.192
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856286
HEPG2	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.00877
Perturb_8894_KD_YAP1/WWTR1_SRP151027	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.16802
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB4-20404135-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06425
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11739
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981186
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.673
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.840915
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSC43673	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
SPI1	ChEA Transcription Factor Targets	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42546
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Congenital disorder of glycosylation type IIb	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01871
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26214
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933098
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54274
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33347
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glycyrrhizic acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514454
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02332
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824366
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98644
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.39855
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36453
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIHA	CCLE Cell Line Gene CNV Profiles	1.0	1.62687
r5 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0159
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50754
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3251
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876768
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47933
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873891
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990225
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23505
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057277
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16037
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944935
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04638
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12054
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.936629
Testicular germ cell cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
20003503-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	2.0136
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31021
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3881
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.138
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09992
Meprin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78917
OPM2	CCLE Cell Line Gene Expression Profiles	1.0	1.3519
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99473
NCI-H2405	COSMIC Cell Line Gene Mutation Profiles	1.0	null
2624_EML2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.599421
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.2087
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04832
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.4106
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64789
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47102
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13970_KD_Hbs1l_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.6904
4695_LSM5_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.509692
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12935
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.33164
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836475
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29818
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS294T	DepMap CRISPR Gene Dependency	1.0	2.35607
IRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91427
ER ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988958
Perturb_12790_KO_Apoe_SRP124787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36658
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8789
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Raltitrexed_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175323
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dami cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07009
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.8791
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830961
medial parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07236
Smoking	DisGeNET Gene-Phenotype Associations	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.766228
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165569
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934428
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52986
PMC10120406-JEM_20220962_DataS2.xlsx-Elf1_target-Data_S2_List_of_Elf1-target_genes_2_d_after_LPS_pIpC_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.548061
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852906
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08722
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943262
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.930984
CL-40	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.37257
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.02985
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472404
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403359
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.84432
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49557
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.05828
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.62575
Perturb_1795_KD_Bud13_SRP168625	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.97483
Tirabrutinib_NCI-H2122	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0285481
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950633
RF-04-GI28_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214584
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55341
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7245
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-E20_624_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845396
Perturb_12765_KO_Atg7_SRP273122	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92669
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0043
Perturb_12138_KD_OTX2_SRP347033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.96024
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48652
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13578_KD_Fem1b_SRP274135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41861
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9852698-mmc6.xlsx-ATF6_Mizuno-Gene_symbol_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.4202
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_16781_KD_Msi2_SRP061564	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.42731
XC-13-LW13_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259731
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10601
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11247
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256234
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331346
A549_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248772
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
ERBB2_druginhibition_6_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72176
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18259
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15117_KD_Rtn4_SRP278924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.43377
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133899
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ORC5	Pathway Commons Protein-Protein Interactions	1.0	null
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59594
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.327
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38667
decreased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6983-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07035
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933795
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26227
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61696
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1199
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sialuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892216
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7494
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892017
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8448_KD_ABL1_SRP212071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35227
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24568
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-14-TCF7L2_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9053
USF1	ENCODE Transcription Factor Targets	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90413
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.981095
HEL	DepMap CRISPR Gene Dependency	1.0	3.0162
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.957009
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95626
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5596
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.417
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23747
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42299
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853952
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUOX2	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.47479
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515423
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9244
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39972
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01247
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191378
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	3.06168
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28444
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.912
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17303
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59298
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216899
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5639-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG16L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1681
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97101
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73533
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847433
IALM_LUNG	CCLE Cell Line Proteomics	1.0	2.82768
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24604
A549_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216164
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66421
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CCP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35298
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20177
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.3674
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856148
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08033
Perturb_15364_KO_Mef2c/Mef2d_SRP064307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Hyperplasia	CTD Gene-Disease Associations	1.0	1.59778
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51524
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33911
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12036_KD_Prmt6_SRP131294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.82555
A549_TMP195_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170525
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPMI8226	DepMap CRISPR Gene Dependency	1.0	3.84822
K562_A-366_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154082
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09886
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67501
Lung adenocarcinoma_LUAD_TCGA-67-3774-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04762
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.65423
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0209
kidney disease	GWASdb SNP-Disease Associations	1.0	1.12155
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
TFEB-21752829-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79686
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.52543
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1281
Perturb_13982_KD_Hbs1l_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.08739
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832973
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89856
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.67075
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05676
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44643
ELK4	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85073
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16513
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989456
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836975
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Atrial heart septal defect 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
opm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19182
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19173
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07382
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51441
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0619
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12602
SMARCA4-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PATU8988T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637494
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4509
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11928
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16479
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72019
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97608
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4884-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.2104
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Benztropine (mesylate)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0216704
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08664
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7545
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.143
Perindopril (erbumine)_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0121071
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10228
Spleen-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	7.44523
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.91738
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Boc-4mesyloxypiperidine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
BD-83-QC82_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24969
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Macrolide transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9611
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927672
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7393
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14525_KO_Foxa2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.8565
PMC4790538__F3	PFOCR Pathway Figure Associations 2024	1.0	null
AA-57-FZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389504
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878554
A549_Ellagic acid_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152117
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51373
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58863
KRT15	Pathway Commons Protein-Protein Interactions	1.0	null
rj2.2.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
Perturb_2354_KD_FOXQ1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.88715
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962467
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IE-19-LI00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.632715
cellular response to stress	GO Biological Process Annotations 2015	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921613
Perturb_3017_KD_Ttn_SRP222910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.53489
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08097
esrra_19901197_kidney_lof_mouse_gpl1261_gse16623	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.10552
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830961
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.858415
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
G43417UB	GlyGen Glycosylated Proteins	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Infertility, Female	CTD Gene-Disease Associations	1.0	1.05349
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Talc_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0254446
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
K562_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130385
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89899
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.16203
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48298
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2250_KO_Piezo1_SRP355856	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.73984
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11148
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06279
biological regulation	GO Biological Process Annotations 2015	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16885
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1026-SM-4AD4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0019
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95317
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52232
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990853
GSE154577_13_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4668_KO_Wdr5/Trp53_SRP324834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.01255
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881707
CAKI2	DepMap CRISPR Gene Dependency	1.0	4.20677
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Red cell distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03871
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55401
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27758
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
Sunitinib_RKO	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00553087
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254615
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.12775
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28431
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973314
CDKN1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
isomerase activity	GO Molecular Function Annotations 2015	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7243
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28473
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14763
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	3.53426
16151515-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_8302_KD_RBM22_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.72006
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08404
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETC-206_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0146413
A549_Aurora A Inhibitor I_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.018258
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22824
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.4488
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4937
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85384
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0233
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
A549_BMS-911543_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130916
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37086
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7086_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.44166
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21172
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
GaMG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.1122
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13441
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2666
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01528
Perturb_11197_KD_Pten_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.2095
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37828
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175920_4_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89802
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54249
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34224
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43628
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.165
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896342
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27574
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.048017
HCoV-EMC2012_3Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.538
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34641
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895247
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166439
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01871
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05533
Cytosolic proteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.452
molecular_function	GO Molecular Function Annotations 2015	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08727
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mean reticulocyte volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68595
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09388
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78605
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10349_KD_Myc_ERP119985	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.53784
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.872085
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.13528
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6481-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.39056
MYOG	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23706
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874416
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835754
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE5	DepMap CRISPR Gene Dependency	1.0	3.11212
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01367
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0822
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8033
increased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13784_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3861
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68227
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.76969
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71298
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Thioredoxin-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37408
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03329
Perturb_6529_KO_YAP1/WWTR1_SRP212224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.96895
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851752
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A48D-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175929
7588_RTN2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542213
A549_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149196
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	2.2618
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08092
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0113
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK3_knockdown_110_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68827
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20329
9-ING-41_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0234363
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04654
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33556
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37881
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TC32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97362
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07804
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02573
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17024
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9576
CHD1	ENCODE Transcription Factor Targets	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.054023
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46674
K562_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164505
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909706
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51177
Perturb_15888_Mut_Tbx5_SRP306874	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96256
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00238
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.29085
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26018
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05234
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37459
Perturb_3533_OE_HLAG_SRP386253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
FLI1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Harringtonine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00925201
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.45737
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the solitary tract, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51857
NGP	DepMap CRISPR Gene Dependency	1.0	3.31143
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14963
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.31317
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.3373
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067975
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17423_KO_Cic_SRP126501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.66668
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26508
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oligosaccharyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33051
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77494
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40256
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43252
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8123
K562_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188989
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3881
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00933
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00633
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.741464
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4602
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031441
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18198
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.01578
Perturb_15291_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87513
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71198
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14624_KD_GOT1_SRP282058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.65985
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_18444_KD_YAP1/WWTR1/STING1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.21736
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_17562_KD_IRAK2_SRP396814	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.08918
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51759
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.327
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1386
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843732
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.985826
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187361
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71851
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869899
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210162
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98875
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.857631
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38856
decreased bone mineral content	IMPC Knockout Mouse Phenotypes	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320217
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41208
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.592529
PMC6138936-13059_2018_1512_MOESM2_ESM.xlsx-SE_H1-_MSC-Gene-symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44684
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939479
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39277
A549_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150875
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34092
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_SupT1_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATXN7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.7687
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1241
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	10.9174
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6673
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00836
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.029297
Zonisamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943191
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23734
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
K562_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.027231
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
NFE2L2-22581777-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106875
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27523
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01381
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3369_KO_Zc3h12a_SRP183512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.7278
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SMSCTR	DepMap CRISPR Gene Dependency	1.0	5.31141
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2-27304074-CHIP-SEQ-NSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.40666
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4706
A549_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129481
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0532
K562_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167017
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.610128
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03613
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86823
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FLT1_knockdown_111_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.04107
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34318
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12957
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32322
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147378
Egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971971
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37163
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00117
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08722
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878163
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845158
OCIM2	DepMap CRISPR Gene Dependency	1.0	5.62222
FOXA1-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65286
GD-71-OU80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22686
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.79316
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90522
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23229
MYC	ENCODE Transcription Factor Targets	1.0	null
LMO2	ChEA Transcription Factor Targets	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953236
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32115
A549_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213775
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57026
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998389
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.37011
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.295
A549_Raltitrexed_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011812
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.847718
Actonel	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975657
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175920_0_v_1_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25147
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83584
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40822
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61487
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30426
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26551
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.77288
4994_METTL16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.889253
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
5791_NR2E1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.558901
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9852698-mmc6.xlsx-ATF6_Nativio-Expression_levels_in_AD_samples_TPM_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9415_KD_Mecom_SRP356893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10085
A549_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161873
MCF7_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120626
PMC12881295-mmc8.docx-0-Genes_in_dataset_downstream_of_XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7299
MBD4	ENCODE Transcription Factor Targets	1.0	null
5927_OGDH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654559
E2F4	ENCODE Transcription Factor Targets	1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.07327
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SM-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1441_CDK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.613028
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39914
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889413
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13565_OE_Nfia_SRP077282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.3583
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00681
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15567
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07892
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838259
GSE175920_0_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.41704
CF-82-LL11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257354
GATA1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MN-01A-22R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.01767
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6895
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.63639
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10947
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933098
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.26132
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44624
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15363_KO_Mettl14_SRP262999	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22498
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52003
4554_LEPROTL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	2.03206
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964078
u26684	HPA Cell Line Gene Expression Profiles	1.0	0.90892
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01068
HT1197	DepMap CRISPR Gene Dependency	1.0	3.77917
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170915
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051467
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901675
BC-20-WA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235405
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32193
Perturb_15098_KD_PDHA1_SRP385600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.58148
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.59931
PMC8384902-mmc5.xlsx-H889_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145792
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47889
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.087
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30113
PDK1_knockout_265_GSE42187	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67941
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GD-73-ZF64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356707
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71261
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47821
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83995
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993071
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22961
BC-26-LE04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233544
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.30329
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Astrocytoma_CNS - Brain (MMHCC)_GSE4290	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.33691
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11859
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3316
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47587
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09252
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.635662
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.867803
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEPG2_LIVER	CCLE Cell Line Proteomics	1.0	3.26005
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.962851
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07333
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36234
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920878
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452969
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.982998
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8480_KD_CSDE1_SRP117243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.87041
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03917
mantle zone of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01476
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4163-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Decitabine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110058
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46301
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPB	Hub Proteins Protein-Protein Interactions	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Derlin-1 retrotranslocation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.21
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.917
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.611
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056003
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356733
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.44
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230405
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34904
GB-73-QS80_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217362
Lung adenocarcinoma_LUAD_TCGA-78-7153-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384445
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01424
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.26135
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9037
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS28BM	CCLE Cell Line Gene Expression Profiles	1.0	1.85556
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0822
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854674
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.30527
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91074
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
K562_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149689
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19554
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK9_druginhibition_183_GSE48258	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.127897
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15544
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17018
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05051
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.132764
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6011
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57326
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Quinestrol_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0106834
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intramolecular oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
increased thigmotaxis	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01326
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197753
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB4	ChEA Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954657
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75118
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6484-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02028
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832225
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56125
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051468
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053796
cellular process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18942
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08152
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.06625
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22725
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33051
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.01137
protein disulfide isomerase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149489
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99461
TBP	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8835
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06505
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.50872
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16075
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20923
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4344
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31435
Flumatinib (mesylate)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0289503
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.043933
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RT112	DepMap CRISPR Gene Dependency	1.0	4.18076
PMC8906867-pbio.3001569.s011.xlsx-HEK_and_SupT1_up_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASPC1	CCLE Cell Line Gene CNV Profiles	1.0	1.52961
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
9396_TTF1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654279
K562_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165456
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41194
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.38479
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21875
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SMARCA4-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6231
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23803
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08918
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.629172
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66047
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38969
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967428
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_SupT1_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_SupT1DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06354
A549_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154297
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16434
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83962
CADO-ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11402_KD_CPT1A_SRP076884	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66485
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992684
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91386
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041953
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5438
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
response to endoplasmic reticulum stress	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64701
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17432
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4982
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923461
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42709
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02201
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460495
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34275
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61721
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.44
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7821
A549_Nintedanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017098
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33688
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898851
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	2.20949
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.950947
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37355
Nuclear microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
NCIH1963	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90301
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6951_KO_Rbm20_SRP328560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.93923
FOXA2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11967
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54355
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252809
PMC12370121-pone.0329101.s003.pdf-2-BATF_BATF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0607
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLR23	DepMap CRISPR Gene Dependency	1.0	2.08215
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5177
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23913
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.73777
PMC6172027-elife-38795-fig2-data2.xlsx-XBP1_RNASeq_only-Gene_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
GSE73628_1_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17369
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848654
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9256
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.06422
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922263
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17001
K562_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01199
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.47904
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09547
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914444
WC-89-JT40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249586
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57405
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247196
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66863
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3621
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8508-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3215
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85964
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60671
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303591
Perturb_13113_KO|KD_Mbnl1/Mbnl2|Mbnl3_SRP045573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.84244
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00364
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47587
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54907
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8047-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5683_NKAP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.548429
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0197
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28172
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75605
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00659
KLF4	ChEA Transcription Factor Targets	1.0	null
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS620	CCLE Cell Line Gene Expression Profiles	1.0	1.43096
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00253
SKNBE2	CCLE Cell Line Gene Expression Profiles	-1.0	-3.43865
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.89722
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.526184
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39409
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19308
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20403
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86526
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0822
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51771
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endoplasmic reticulum	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A76A-01A-51R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.947918
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18138
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.725352
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2242
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	1.0	1.0805
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08039
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835654
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914613
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.8707
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61949
Perturb_6492_KO_Atrx_SRP323952	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
A549_Nintedanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148402
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0282
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2373
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EB-66-IH06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287742
Perturb_17869_KO_Sh2b3_SRP052872	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21691
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03983
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27132
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64773
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
NFIB-24661679-E16.5 LUNG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33704
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26941
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969458
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09005
Perturb_13071_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39848
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZW-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17886
GSE208254_4_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849117
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314501
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.44
EJM	CCLE Cell Line Gene Expression Profiles	1.0	2.75524
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8669-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08231
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39667
9962_ZBED2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.623287
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957851
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85659
Perturb_13296_OE_Pik3ca_SRP173204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.78433
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.431
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1199
cho/dhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
NFE2L2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931808
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gonadal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
AD-34-TG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208027
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850994
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
TCCPAN2_PANCREAS	CCLE Cell Line Proteomics	1.0	3.88881
K562_Maraviroc_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166634
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317535
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14634
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.876799
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.20704
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27986
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969458
UOK101	DepMap CRISPR Gene Dependency	1.0	4.07882
AF-73-HJ84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247037
TE14_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.32669
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210667_3_v_2_rfx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0449
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.896436
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16739_KO_Gcn5_SRP271119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.26323
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19S-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172295_4_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.492293
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2065
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23896
Hypertrophy	CTD Gene-Disease Associations	1.0	1.14713
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - PBMC - L3 - Plasma cell	HuBMAP Azimuth Cell Type Annotations	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.44
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00633
NOS3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24042
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830802
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.345
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35163
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4089
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01871
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34242
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045715
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IC-98-UO17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243234
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912189
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39987
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.962436
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48653
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09132
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12808
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2454
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829885
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.38597
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03122
pontine reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83982
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Q777G9	Virus MINT Protein-Viral Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.11907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00205
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04594
FF-54-JC89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217013
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.075597
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5179
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202352
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	CCLE Cell Line Gene Expression Profiles	1.0	1.60319
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899212
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37855
PML	ENCODE Transcription Factor Targets	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61949
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09205
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23281
Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	5.37213
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13896_KO_TLR3/MYD88_SRP332441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.55031
GSE135030_8_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLT4_knockdown_103_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.91267
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08349
A549_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157254
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Obatoclax Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0291837
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55651
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	2.39914
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12425
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917393
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86789
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9999
Testicular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28268
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Testicular cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906918
LP1	CCLE Cell Line Gene Expression Profiles	1.0	2.01719
NFYA	ENCODE Transcription Factor Targets	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06435
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2126
hESC_Derived_CD184+_Endoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.27891
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09101
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03676
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211829_9_v_1_tafasitamab_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03908
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959267
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357877
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.34197
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.905046
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00919
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11479
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0647
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51673
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975541
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05901
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75982
ZFX-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6837
Sarcoma_SARC_TCGA-DX-A3U5-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840188
SVGp12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4482
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4413
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15104
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916353
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.33081
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46857
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04666
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045854
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47258
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58083
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13695
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98579
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46795
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09626
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.4532
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189357
Salivary_Gland-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.418886
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19476
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36824
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32553
K562_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016442
Myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84672
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0678
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317208
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27543
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_9_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_4962_KO_Dot1l_SRP214101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.17367
A549_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136882
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944118
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Blood-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.266203
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71397
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07829
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0915
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936714
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4611
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17898
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41019
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2417
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27577
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27495
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42237
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33349
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03178
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665977
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43143
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.36411
BMS309403	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
PMC11991920-41556_2025_1639_MOESM10_ESM.xlsx-DEGs_MI_4-oxo_vs_MI_Ctrl_HSPCs-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.64061
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.45907
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-59-OG21_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448237
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29193
Perturb_15088_KO_Yap1/Wwtr1_SRP303521	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.45529
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.59319
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12543
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101169
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10160_ZNF121_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.539631
Perturb_4719_KO_Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DB-29-HQ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251027
POU5F1-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02982
Intine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.498
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90813
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40625
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96279
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02208
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040082
9751_VPS35_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512326
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19084
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053193
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	2.63487
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6857
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16663
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0822
GSE111102,GSE111105_8_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31965
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5460-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829815
Perturb_4456_KD_Mecp2_SRP125116	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46656
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947751
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5042_Mut_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.0505
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39813
Perturb_4714_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39492
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065481
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39187
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016776
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.327
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.39634
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476795
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.005
NR2F2	ENCODE Transcription Factor Targets	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17296
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
K562_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182171
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05073
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969011
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81439
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
A549_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178459
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14474
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873562
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6199
RD_SOFT_TISSUE	CCLE Cell Line Proteomics	1.0	4.01
RND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05142
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20402
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57767
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991962
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969867
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Rucaparib (phosphate)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0131545
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	2.30978
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43318
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09573
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884177
DMS273_LUNG	CCLE Cell Line Proteomics	1.0	2.00605
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26328
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00981
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22172
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.46224
G39188ZX	GlyGen Glycosylated Proteins	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38329
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23991
8222_SNRNP70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.52061
TAL1_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24227
VDR-20736230-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.02783
Perturb_16693_KO_Ly6e_SRP250973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.06883
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21941
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-82-TS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237378
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071982
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053135
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18978
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.114588
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015671
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951803
A549_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172187
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESRRB	ChEA Transcription Factor Targets	1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.636635
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03618
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50645
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.39702
K562_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250322
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL51	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88659
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3605
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SB290157	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
K562_MC1568_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153723
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4847
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-DS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278394
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.26582
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32098
A549_Tucidinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151791
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978044
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830961
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.917
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19018
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67809
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19664
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94626
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MM1-S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2405	CCLE Cell Line Gene CNV Profiles	1.0	1.36887
A549_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156899
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.79217
Perturb_14534_KO_Ptf1a/Gata4_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916512
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90242
Perturb_16536_KO_Ptger4_SRP238348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73347
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257505
K562_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185108
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HC-18-NB46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265562
4957_MED7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567825
TAL1	ENCODE Transcription Factor Targets	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.86006
Perturb_8689_KD_FAT1_SRP358313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56431
CAOV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142406
Adenocarcinoma of lung_Lung Tissue_GSE1037	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57262
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homeostatic process	GO Biological Process Annotations 2015	1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.49559
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880549
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34828
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55726
CDK2_knockdown_90_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.56149
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.097
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TAL1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55665
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61744
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.33067
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.08731
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40464
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865974
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34232
K562_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246167
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.989771
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844975
K562_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202917
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3725-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.64822
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06512
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23604
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
7166_RBM25_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.535703
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18771
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02773
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57261
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829158
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.887866
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.836728
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00294
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64658
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1434
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824402
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999015
4909_MCPH1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654502
KBM-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
ARID3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150762
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25867
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.994124
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-421_ChIP-Seq_H3K9me1_2_AR_differential_expression_upon_KDM3A_or_AR_knockdown_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ULK1_knockout_197_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48933
PMC3430588-1477-3155-10-16-S5.pdf-21-ZNF687_ZNF687	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11639743-mmc2.xlsx-LIN28B-gene_name_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38111
GABPA	ENCODE Transcription Factor Targets	1.0	null
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.975989
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
(S)-Crizotinib_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0127337
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153333
RXRA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uridine_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00879046
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8183
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4018
Perturb_13945_KD_CDK12_SRP168173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56936
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880371
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860007
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938794
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
efp1	GeneRIF Biological Term Annotations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356393
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57081
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48329
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_A549_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26136
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08884
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26703
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61949
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89794
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08409
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867946
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.08865
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5945
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941995
protein folding	GO Biological Process Annotations 2015	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.3641
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.06935
Lonafarnib_HT-29	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00412565
EARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57613
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00528
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.4465
ILF3-29590119-K562-HUMAN-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_16856_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.04202
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153189_1_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1027
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972338
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47464
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13786_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5878
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969925
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854391
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48276
K562_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168659
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.47508
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15538
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940534
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50968
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30086
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.60441
A549_Roxadustat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172369
A549_Meprednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196583
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HEL9217_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.08602
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2689
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31532
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641458
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38975
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975506
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endoplasmic reticulum part	GO Cellular Component Annotations 2015	1.0	null
STAT1_01_21	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.585
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7UA-06A-32R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57648
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73772
testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Belzutifan_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00831918
A549_FLLL32_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152258
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96081
SARS-BatSRBD_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57636
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09209
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06294
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34762
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DERL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06037
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08727
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90168
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.99426
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16037
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0926-SM-4DXSW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917232
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67371
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_HEK293DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ameloblastic layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04318
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5117
BD-48-ZT65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268285
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22102
A549_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020345
Levobupivacaine (hydrochloride)_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0170523
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08103
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955288
POLR2A_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14793
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17999
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172115
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29473
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47967
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45624
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0077
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149627
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845493
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40705
IC-05-AW29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.548792
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.264
cell redox homeostasis	GO Biological Process Annotations 2015	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.88294
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFIB-24661679-LUNG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0452
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.327
membrane region	GO Cellular Component Annotations 2015	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02395
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31462
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135974
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934428
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167078
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932651
HT-1376	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.725352
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07287
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828744
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99633
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26061
K562_Prednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225055
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.22434
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K562_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0207685
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32679
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01883
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04536
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.41495
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74787
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-67-WB79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318714
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7298_KD_PCIF1_SRP162223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3971
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172531
Perturb_4681_KO_Psip1/Hdgfl2_SRP153901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.66862
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31379
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glycyrrhizic acid_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0185421
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053063
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925988
Perturb_14641_KO_Lats1/Lats2_SRP189870	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78435
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.02451
YSCCC	DepMap CRISPR Gene Dependency	1.0	2.15365
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NYNRIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.054
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16972
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21231
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Alvespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153549
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2351_KD_CNBP_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.61247
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42242
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10528
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.62105
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39599
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.19665
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280012
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19634
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07704
SARS-BatSRBD_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13314
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55469
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09537
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905219
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73672
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836787
Perturb_4715_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_10214_KO_Csnk1a1_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.30707
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2587
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4626
7-Hydroxycoumarine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12294
A549_FLLL32_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206877
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37754
(Z)-Pugnac	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42465
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30041
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08805
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7874
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01515
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148252_8_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.493
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53802
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149635
MM1-R cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.960942
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00294
K562_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187447
W-13 HCl	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.92651
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918449
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908714
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11385
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357824
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02353
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27172
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832347
CNOT3	ChEA Transcription Factor Targets	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29514
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04226
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47544
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.292
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1576
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1294
K562_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221197
SNU308	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43176
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923366
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	2.91057
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49978
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10075
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45151
KRT18	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_4817_KO_Neil1_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.59137
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30921
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.275
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16764_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9634
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.84921
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11762_KO_Irgm1_ERP020504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.88807
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37642
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04437
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.2423
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924374
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12671
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558903
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.836
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56254
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3324
KYM1	DepMap CRISPR Gene Dependency	1.0	4.33833
gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.617311
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02853
3871_HNRNPL_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.736057
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02566
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Necrostatin 2	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4359
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74888
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319183
K562_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159118
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39629
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEPG2	CCLE Cell Line Gene CNV Profiles	1.0	1.683
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33933
TBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64093
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.135
PLK2_knockdown_87_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.55845
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1372
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13048
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05521
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14613
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.48362
NCIH1568_LUNG	CCLE Cell Line Proteomics	1.0	3.41549
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42481
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92821
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11526
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.728254
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46413
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735889
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1681_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.43283
Teratocarcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31524
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_TGX-221_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212924
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61128
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20504
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831479
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma renin activity levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85077
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20245
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7962
dbtrg05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02519
GSE178340_1_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166318
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896952
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Hrd1p ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
MCF7_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118452
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.05408
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
upper basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00929
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00836
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916878
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.07726
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.47778
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.838066
CHD1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826909
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.47839
4153_INTS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.596716
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.03419
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888882
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2413
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55472
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55121
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24587
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.43673
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09419
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07079
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6448
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05939
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57422
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66086
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31506
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969529
FOXA1	ENCODE Transcription Factor Targets	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05689
MZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08698
Perturb_4818_KO_Neil2_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73319
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919004
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209888
KB-88-OR49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330545
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.917
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10919
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0935
Perturb_16721_KO_Brca1_SRP094855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.0798
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230196
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34961
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZFX	ChEA Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88468
DE-73-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372744
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08441
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969369
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.546653
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Parvicellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15468
Perturb_8507_KO_Gata4_SRP277626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44499
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110932
K562_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214643
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054284
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11748
Perturb_2331_KD_SNRPB_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89937
715_AURKB_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.671652
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913827
4932_MED12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.692928
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899505
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00291
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46907
TASK1	DepMap CRISPR Gene Dependency	1.0	3.51861
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0043
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58585
lp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13226
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.40813
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24372
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1361
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28277
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19725
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998881
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903533
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.899437
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07506
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61985
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.455
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.50113
E2F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-90-AA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273203
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	0.380309
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10245
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04631
Perturb_10418_KD_Nuak1_ERP105467	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.13384
MAFF	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-157	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.819019
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58208
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178054
PMC12079334-ADVS-12-2501734-s002.pdf-154-ENSG00000006194_ZNF263	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59473
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
thioredoxinrelated	GeneRIF Biological Term Annotations	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	1.0	1.62028
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06201
GSE231891_1_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	3.13771
BE-66-UB12_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454063
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975378
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4720_KD_Tp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.81708
Lung squamous cell carcinoma_LUSC_TCGA-60-2712-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832717
A549_Ellagic acid_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145141
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01243
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
lung	GTEx Tissue Gene Expression Profiles	1.0	1.21001
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9099
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SG-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13946
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.03567
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163219
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6487-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37494
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0214
CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FUS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13564_OE_Nfia_SRP077282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.84549
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.84
Smoking Behaviors	DisGeNET Gene-Phenotype Associations	1.0	null
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31308
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08646
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25389
KMS26	CCLE Cell Line Gene Expression Profiles	1.0	1.68334
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
rostral secondary prosencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19418
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874509
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3772
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4733-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04824
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0280709
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32466
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862461
B cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
TAL1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_TGX-221_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154384
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42128
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE200352_9_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9852698-mmc4.xlsx-Selected_PERK_IRE1_ATF6_ERAD-gene_symbol_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL311	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70996
intramolecular oxidoreductase activity, transposing s-s bonds	GO Molecular Function Annotations 2015	1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882967
PMC8102188-41375_2021_1231_MOESM4_ESM.xlsx-t_som_AA_healthy-Unnamed_7_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FLI1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular homeostasis	GO Biological Process Annotations 2015	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50502
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870966
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.3242
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03905
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Resveratrol_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153311
HMGN3	ENCODE Transcription Factor Targets	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.104462
FLI1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
MEF2A-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21632
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49047
K562_AMG-900_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134605
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58087
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7781_KD_HNRNPU_SRP019270	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.5229
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978216
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62217
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0792
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889788
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
4371_KIAA1958_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510282
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_02_40	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58847
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Testicular cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1186
RFX5	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51527
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38323
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1884
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21895
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44411
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1081_KO_BACH1_SRP174544	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3853
Serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58825
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17018
GSE175920_4_v_1_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876679
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912843
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52871
PHF8	ENCODE Transcription Factor Targets	1.0	null
SARS-dORF6_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.85052
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899075
Perturb_11775_KO_83F24Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.74585
Anastrozole_AsPC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223876
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58025
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.887301
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IKBKB_knockdown_86_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.69657
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292655
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829505
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10528
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42579
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04442
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912984
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.988931
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.47933
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55819
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057948
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373593
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.31653
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994136
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65783
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13783
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92334
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34453
Perturb_9436_KO_Mapk14_SRP308388	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31647
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4961_KO_Dot1l_SRP214101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40779
HNF4A	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39345
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48852
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81216
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0627
Neoplasms	CTD Gene-Disease Associations	1.0	1.17399
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39506
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27177
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.24027
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16347
metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15713
A549_EED226_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155069
CDK9_knockdown_104_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.19186
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29806
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1116
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-85-OX77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404193
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03657
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.32428
Lonafarnib_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00448905
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.77157
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal bone structure	MGI Mouse Phenotype Associations 2023	1.0	null
K029AX_SKIN	CCLE Cell Line Proteomics	1.0	3.39351
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898851
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4136
Perturb_13298_OE_Pik3ca_SRP173204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.8789
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83425
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lidocaine (hydrochloride)_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0088615
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.96594
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952043
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
K562_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01722
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254191
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90265
Perturb_9130_KD_PHGDH_ERP020769	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.5391
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44198
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6857
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297732
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07428
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9023
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41712
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.158
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.39308
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17796
RPMI-8226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
r5 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09179
K562_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188006
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145495
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838306
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941679
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.17833
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10741_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.14177
increased circulating cholesterol level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829885
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73012
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RC-21-IF98_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204217
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	4.75185
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.102
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epstein-Barr virus (strain GD1)	Virus MINT Protein-Virus Interactions	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824503
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042156
Perturb_10778_KO_Xbp1_SRP051964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6881
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19176396-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18459
MEF2A	ChEA Transcription Factor Targets	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71458
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03508
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73717
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02744
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2C2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08277
STAT3	ENCODE Transcription Factor Targets	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.901393
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20246
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.959456
K562_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0262572
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Balsalazide (sodium hydrate)_SW 1088	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0215118
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14926
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00133
1129_SPOUT1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.13737
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39319
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_2539_KD_ZMIZ1_SRP212150	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.93374
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10528
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15273
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E5-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832968
Infigratinib_HepG2/C3A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00647762
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21801
A549_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159845
K562_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01846
MM1S	CCLE Cell Line Gene Expression Profiles	1.0	2.41414
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11461
A549_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014882
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7338
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871043
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.44
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862639
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02332
A549_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143123
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862825
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21916
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18074
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952996
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969458
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19749
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multicellular trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.679
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933692
A-CA-04-2009(H1N1)_12Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.57133
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982675
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.37208
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34931
TFAP2A	ChEA Transcription Factor Targets	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252886
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212881
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11804
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19074
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835654
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01059
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45163
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134905
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.996578
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.725352
Perturb_5482_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.91693
Nucleus of the solitary tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52644
Sperm head plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.762
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23138
ARNT_01_315	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.592
MCF7_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201577
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82586
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06967
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.382
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24608
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02606
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2860-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18952
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.682861
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89211
Perturb_5757_KO_C9orf72/Tmem173_SRP266242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.32448
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26642
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84236
ACAA1	Pathway Commons Protein-Protein Interactions	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
Perturb_12791_KO_Trem2_SRP124787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.41325
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920305
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1-26751641-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.386
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.38794
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0194851
IA-27-CK10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35572
Fatty Liver	CTD Gene-Disease Associations	1.0	1.56804
MCF7_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169466
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6454
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A4EO-06A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139123
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00338
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.074169
SOCS3	Pathway Commons Protein-Protein Interactions	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.862137
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04265
Perturb_17415_OE_Gata3_SRP150425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.78227
RPL39L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23337
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91074
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1822_KO_Irf5_SRP233379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.60116
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0077
binding	GO Molecular Function Annotations 2015	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44399
K562_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141234
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12659
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99039
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.68939
2925_FAM50A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533501
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.08169
GATA1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.1107
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09472
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6869
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4869
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06133
Perturb_1111_KD_Creb3l1_SRP255011	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70269
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24167
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907317
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92349
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97461
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825552
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.68954
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23193
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79291
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
RELA	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	1.35824
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79177
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	2.05692
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07203
Gefitinib_SW1417	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0135076
A549_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0094764
Perturb_2357_KD_PRRX1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.37268
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67815
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_18440_KD_CGAS_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.90002
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30706
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29272
Perturb_9416_KD_Mecom_SRP356893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.99059
CHUK_knockdown_108_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75727
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24866
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555274
Perturb_12899_KD_IRF3_SRP298451	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TBX5	ChEA Transcription Factor Targets	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11716
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00527
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGBC24TKB	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
u266	HPA Cell Line Gene Expression Profiles	1.0	1.59809
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168545
FD-35-PQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534299
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557128
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423504
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851181
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24359
VDR	ChEA Transcription Factor Targets	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.34779
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70327
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6299
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519296
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08035
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845396
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38108
EKVX	DepMap CRISPR Gene Dependency	1.0	3.43455
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33434
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76978
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.078
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948891
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14723
A549_Roxadustat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125645
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3363
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922458
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.942945
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37793
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX17	ChEA Transcription Factor Targets	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.902326
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03927
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01431
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11787
NFIB	ChEA Transcription Factor Targets	1.0	null
K562_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159108
Endoplasmic reticulum quality control compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053
BE-66-UB12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206707
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16037
HIPK2_defectivemutant_29_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5929
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.44675
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05852
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
TGFBR1_knockdown_102_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.42058
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.315714
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54798
A549_Daphnetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164815
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4553
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14895_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84045
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Fasudil_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137172
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827702
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054173
decreased locomotor activity	IMPC Knockout Mouse Phenotypes	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0573
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.974995
MCF7_Trichostatin A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00671435
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86181
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00096
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4115
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5828413__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06972
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46658
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832601
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40378
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04123
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932872
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34232
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871284
EW8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.82304
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0205086
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23739
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45398
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A549_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172859
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19354
Perturb_13822_OE_Efgr_SRP302970	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71384
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934647
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19694
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_mus musculus_gpl7509_gse14774	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7764-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Plant stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03582
Bladder-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	1.61686
A549_Selisistat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174449
Hesperidin_COLO 205	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0113164
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6952_KO_Rbm20_SRP328560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55807
Perturb_6131_KO_Sesn1/Sesn2_SRP294204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.54914
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3051
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29665
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052133
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2995
SPI1-23547873-NB4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SW982	DepMap CRISPR Gene Dependency	1.0	2.4006
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.977865
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.576178
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209194
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08497
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25099
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77387
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318635
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8357
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170466
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53201
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02908
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5328
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968324
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15184
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12191
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19828
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08888
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895017
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.84823
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837553
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198036,GSE198041_0_v_2_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.32725
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66123
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40182
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73103
JUN_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.288958
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07804
GSE120612_6_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pronephros	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18667
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74066
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20111
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198918
NCIH1650	DepMap CRISPR Gene Dependency	1.0	3.1566
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00916789
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62742
Inflammation	CTD Gene-Disease Associations	1.0	1.70988
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1743_KO_U2af1_SRP297129	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.0418
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-22-VC55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240704
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31789
decreased bone mineral content	MGI Mouse Phenotype Associations 2023	1.0	null
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.49826
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053604
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2964
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.085402
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9303
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991281
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871608
Phenylboronic acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.8902
MCF7_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128016
CREB1	ChEA Transcription Factor Targets	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08832
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.336704
K562_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156236
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Celecoxib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179269
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41697
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	1.54123
SETDB1_02_52	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5877
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3471
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35865
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887524
POU2F2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TPO	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414195
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12775
Rdw - Red Blood Cell Distribution Width Result	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-84-KP45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320981
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14578
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08652
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70471
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933098
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23138
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KELLY	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05574
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
RXRA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56481
EBF1	ENCODE Transcription Factor Targets	1.0	null
Pancreas-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	0.292629
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
partner	GeneRIF Biological Term Annotations	1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3787
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15609
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851783
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898851
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.085
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Red Cell Distribution Width Determination	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A549_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205478
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44694
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01429
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02389
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92573
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15663
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272637
K562_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195117
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.938856
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181635
MCF7_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136093
2,4-Dichlorophenol	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
3622_HADHB_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510467
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13125
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64751
NCI-H747	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8368_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.68232
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09994
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158339
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49126
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41998
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8761
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.224
GFI1B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36795
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201818
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935998
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3196
Weight	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
TAL1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88626
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05617
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74114
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04811
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tazemetostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159067
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.15754
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930039
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0336
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874358
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178439
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0879
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.182
GRANTA519	CCLE Cell Line Gene Expression Profiles	1.0	2.1111
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D2REFED4h_641_AR-D-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BF-29-LU75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204988
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4725_KO_Irx3_ERP116672	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.7292
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.12581
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51411
GSE84148,GSE96938_0_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25034
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.6189
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF	ChEA Transcription Factor Targets	1.0	null
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983615
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44258
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854551
Perturb_13568_KD_Kctd10_SRP292969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.91259
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138485
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.716
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00866
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27692
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08251
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17702
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12641
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.590977
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24614
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51601
AD-40-WB93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266167
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.035703
LU99	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50672
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555857
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82693
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49638
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14552
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.114
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8557
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.049
17284527-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11016
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28757
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040229
Perturb_9661_KD_circTTN1_SRP260174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.1488
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47035
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30078
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0007
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
CC-04-YT10_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2657
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893209
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.0361
PMC12077394-giaf035_giga-d-24-00380_revision_2.pdf-15-HMG20B_HMG20B	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38926
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10966
SNU308	CCLE Cell Line Gene Expression Profiles	1.0	1.49219
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vestibular nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12543
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40593
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25079
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225659
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phragmoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14687
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54212
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22152
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34033
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.84281
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48076
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914591
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21112
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23035
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04693
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49764
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5787
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6582
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983707
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-A5C4-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1515_KO_Ciao2b_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40077
A549_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148988
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Verapamil_HS-578T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0077962
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4717_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15717
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.69191
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.989276
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326512
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40727
PMC12077394-giaf035_giga-d-24-00380_revision_1.pdf-15-HMG20B_HMG20B	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36768
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28015
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.76526
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3a_DirectGene_CEBPA-Data3a_Genes_directly_regulated_by_CEBPA_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24465
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862445
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6964
PRICKLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23055
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269934
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Multiple myeloma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
A549_Decitabine_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117494
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18543
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12392
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827497
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1959
duox	GeneRIF Biological Term Annotations	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.031387
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0069
AKT1_knockdown_123_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.74208
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75116
Inferior salivatory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13374
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01288
KAT2B	ENCODE Transcription Factor Targets	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991217
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894851
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.04322
E2F4	ChEA Transcription Factor Targets	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873113
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01919
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.73804
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16532
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02264
A549_Tubastatin A HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133094
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
6708_PPWD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.717834
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.5335
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147519
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06586
Uterine corpus endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
CEBPD	ChEA Transcription Factor Targets	1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76627
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6343-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9962
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXM1	ENCODE Transcription Factor Targets	1.0	null
OV56_OVARY	CCLE Cell Line Proteomics	1.0	2.0667
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
Clozapine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.43
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922119
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.85305
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.122
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.744
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	1.96446
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28681
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.316
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.44139
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.381
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.59652
MELHO	CCLE Cell Line Gene CNV Profiles	1.0	1.53885
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23138
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20465
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35227
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.89
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943166
SPI1_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985075
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130429
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73964
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12871
Ebolavirus(EBOV)_2day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.99926
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475758
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2781
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214596,GSE214598_1_v_4_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.586
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01355
16397240-SuppTable9	GeneSigDB Published Gene Signatures	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76987
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040322
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944239